General
Kaiguang Yang Ph.D
Professor
Key Laboratory of Separation Science for Analytical Chemistry
Dalian Institute of Chemical Physics
Chinese Academy of Sciences
Research Areas
New techniques and methods of proteomics; Novel Materials for protein enrichment and separation; Molecular imprinting
Education
2007.9--2009.2 Lund University, joint Ph.D student
2003.9--2009.6 Sichuan University, Biomedical Engineering, Doctor
1999.9--2003.6 Chengdu University of Technology, Chemical Engineering, Bachelor
Experience
2009-2011, Dalian Institute of Chemical Physics, CAS, Assisstant Professor
2011-2015, Dalian Institute of Chemical Physics, CAS, Associate Professor
2015- Dalian Institute of Chemical Physics, CAS, Professor
Publications
Papers
(1) Surface sieving coordinated IMAC material for purification of His-tagged proteins, Analytica Chimica ACTA, 2018, 第 1 作者
(2) Proteomics Investigations into Serum Proteins Adsorbed by High-Flux and Low-Flux Dialysis Membranes, Proteomics-Clinical Application, 2017, 第 1 作者
(3) Aptamer-immobilized open tubular capillary column to capture circulating tumor cells for proteome analysis, Talanta, 2017, 第 1 作者
(4) Proteomic study provides new clues for complications of hemodialysis caused by dialysis membrane, Science Bulletin, 2017, 第 1 作者
(5) Multiepitope Templates Imprinted Particles for the Simultaneous Capture of Various Target Proteins, Anal. Chem., 2016, 第 1 作者
(6) Thermoresponsive Epitope Surface-Imprinted Nanoparticles for Specific Capture and Release of Target Protein from Human Plasma, ACS Appl. Mater. Interfaces, 2016, 第 1 作者
(7) Epitope imprinting enhanced IMAC (EI-IMAC) for highly selective purification of His-tagged protein, J. Mater. Chem. B, 2016, 第 1 作者
(8) Boronic Acid-Functionalized Particles with Flexible Three-Dimensional Polymer Branch for Highly Specific Recognition of Glycoproteins, ACS Appl. Mater. Interfaces, 2016, 第 1 作者
(9) Preparation of surface imprinted core-shell particles via a metal chelating strategy: specific recognition of porcine serum albumin, Microchim. Acta, 2016, 第 2 作者
(10) Clickable Periodic Mesoporous Organosilica Monolith for Highly Efficient Capillary Chromatographic Separation., Anal. Chem., 2016, 第 3 作者
(11) Surface-imprinted nanoparticles prepared with a His-tag-anchored epitope as the template, Anal. Chem., 2015, 第 2 作者
(12) An efficient approach to prepare boronate core-shell polymer nanoparticles for glycoprotein recognition via combined distillation precipitation polymerization and RAFT media precipitation polymerization, Chem Commun, 2015, 第 2 作者
(13) Dandelion-like core–shell silica microspheres with hierarchical pores, RSC Adv., 2015, 第 2 作者
(14) Glycoprotein recognition by water-compatible core-shell polymeric submicron particles, J. Mat. Chem. B, 2015, 第 3 作者
(15) Polyethyleneimine-modified graphene oxide nanocomposites for effective protein functionalization, Nanoscale, 2015, 第 3 作者
(16) Epitope imprinted polyethersulfone beads by self-assembly for target protein capture from the plasma proteome, Chem Commun, 2014, 第 1 作者
(17) Monodisperse Boronate Polymeric Particles Synthesized by a Precipitation Polymerization Strategy: Particle Formation and Glycoprotein Response from the Standpoint of the Flory-Huggins Model, ACS Appl. Mater. Interfaces, 2014, 第 3 作者
(18) Surface Protein Imprinted Core–Shell Particles for High Selective Lysozyme Recognition Prepared by Reversible Addition–Fragmentation Chain Transfer Strategy, ACS Appl. Mater. Interfaces, 2014, 第 1 作者
(19) Preparation of protein imprinted materials by hierarchical imprinting techniques and application in selective depletion of albumin from human serum, Sci Rep, 2014, 第 4 作者
(20) Transferrin recognition based on a protein imprinted material prepared by hierarchical imprinting technique, Microchim. Acta, 2013, 第 2 作者
(21) Hydrophilic immobilized trypsin reactor with magnetic graphene oxide as support for high efficient proteome digestion, J. Chromatogr. A, 2012, 第 2 作者
(22) Protein Imprinted Materials: Rational Design, Application and Challenges, Analytical and Bioanalytical Chemistry, 2012, 第 1 作者
(23) Preparing a metal-ion chelated immobilized enzyme reactor based on the polyacrylamide monolith grafted with polyethylenimine for a facile regeneration and high throughput tryptic digestion in proteomics, Analytical and Bioanalytical Chemistry, 2012, 通讯作者
(24) Boronic acid functionalized core-shell polymer nanoparticles for selective enrichment of glycopeptides, Chemistry - A European Journal, 2012, 第 3 作者
(25) A novel organic-inorganic hybrid monolith for trypsin immobilization, Sci. China-Life Sci., 2011, 第 3 作者
(26) Urea free and more efficient sample preparation method for mass spectrometry based protein identification via combining the formic acid-assisted chemical cleavage and trypsin digestion, Talanta, 2011, 通讯作者
(27) Preparation of a new type of affinity materials combining metal coordination with molecular imprinting, Chemical Communications, 2011, 第 2 作者
(28) Macroporous molecularly imprinted monolithic polymer columns for protein recognition by liquid chromatography, Journal of separation science, 2010, 第 3 作者
(29) Self-Assembly Molecularly Imprinted Nanofiber for 4-HA Recognition, Analytical Letters, 2010, 第 3 作者
(30) One-Pot Synthesis of Hydrophilic Molecularly Imprinted Nanoparticles, Macromolecules, 2009, 第 1 作者
(31) Molecularly imprinted porous polysulfone particles for the binding and recognition of bisphenol A, Desalination, 2009, 第 1 作者
(32) BPA transfer rate increase using molecular imprinted polyethersulfone hollow fiber membrane., J. Membr. Sci., 2008, 第 4 作者
(33) Effect of the template molecules and nonsolvent additives on the recognition property of molecular imprinted polyethersulforte particles., J. Appl. Polym. Sci., 2008, 第 4 作者
(34) Preparation and selective binding characterization of bisphenol a imprinted polyethersulfone particles, J. Appl. Polym. Sci., 2007, 第 1 作者
(35) DNA-loaded porous polyethersulfone particles for environmental applications I. Preparation, J. Appl. Polym. Sci., 2005, 第 3 作者
(36) DNA-loaded porous polyethersulfone particles for environmental applications II. Utilization, J. Appl. Polym. Sci., 2005, 第 2 作者
(37) Characterization of DNA-loaded porous polyethersulfone particles prepared by phase inversion technique., Colloid Journal, 2005, 第 2 作者
(38) Molecularly imprinted polyethersulfone microspheres for the binding and recognition of bisphenol A, Anal. Chim. Acta, 2005, 第 1 作者
(39) Preparation of DNA-encapsulated polyethersulfone hollow microspheres for organic compounds and heavy metal ions removal, Desalination, 2005, 第 1 作者
(40) DNA-modified porous polysulfone microspheres for selective removal of endocrine disruptors, Chemical Journal of Chinese Universities-Chinese, 2005, 第 2 作者
(41) Preparation of DNA hybrid polyethersulfone microspheres for endocrine disruptor removal, Key Engineering Materials, 2005, 第 2 作者
(42) DNA-immobilized porous polysulfone beads for organic compounds and heavy metal ion removal., Desalination, 2004, 第 2 作者
(43) Preparation of porous polysulfone beads for selective removal of endocrine disruptors, Separation and Purification Technology, 2004, 第 3 作者
(2) Proteomics Investigations into Serum Proteins Adsorbed by High-Flux and Low-Flux Dialysis Membranes, Proteomics-Clinical Application, 2017, 第 1 作者
(3) Aptamer-immobilized open tubular capillary column to capture circulating tumor cells for proteome analysis, Talanta, 2017, 第 1 作者
(4) Proteomic study provides new clues for complications of hemodialysis caused by dialysis membrane, Science Bulletin, 2017, 第 1 作者
(5) Multiepitope Templates Imprinted Particles for the Simultaneous Capture of Various Target Proteins, Anal. Chem., 2016, 第 1 作者
(6) Thermoresponsive Epitope Surface-Imprinted Nanoparticles for Specific Capture and Release of Target Protein from Human Plasma, ACS Appl. Mater. Interfaces, 2016, 第 1 作者
(7) Epitope imprinting enhanced IMAC (EI-IMAC) for highly selective purification of His-tagged protein, J. Mater. Chem. B, 2016, 第 1 作者
(8) Boronic Acid-Functionalized Particles with Flexible Three-Dimensional Polymer Branch for Highly Specific Recognition of Glycoproteins, ACS Appl. Mater. Interfaces, 2016, 第 1 作者
(9) Preparation of surface imprinted core-shell particles via a metal chelating strategy: specific recognition of porcine serum albumin, Microchim. Acta, 2016, 第 2 作者
(10) Clickable Periodic Mesoporous Organosilica Monolith for Highly Efficient Capillary Chromatographic Separation., Anal. Chem., 2016, 第 3 作者
(11) Surface-imprinted nanoparticles prepared with a His-tag-anchored epitope as the template, Anal. Chem., 2015, 第 2 作者
(12) An efficient approach to prepare boronate core-shell polymer nanoparticles for glycoprotein recognition via combined distillation precipitation polymerization and RAFT media precipitation polymerization, Chem Commun, 2015, 第 2 作者
(13) Dandelion-like core–shell silica microspheres with hierarchical pores, RSC Adv., 2015, 第 2 作者
(14) Glycoprotein recognition by water-compatible core-shell polymeric submicron particles, J. Mat. Chem. B, 2015, 第 3 作者
(15) Polyethyleneimine-modified graphene oxide nanocomposites for effective protein functionalization, Nanoscale, 2015, 第 3 作者
(16) Epitope imprinted polyethersulfone beads by self-assembly for target protein capture from the plasma proteome, Chem Commun, 2014, 第 1 作者
(17) Monodisperse Boronate Polymeric Particles Synthesized by a Precipitation Polymerization Strategy: Particle Formation and Glycoprotein Response from the Standpoint of the Flory-Huggins Model, ACS Appl. Mater. Interfaces, 2014, 第 3 作者
(18) Surface Protein Imprinted Core–Shell Particles for High Selective Lysozyme Recognition Prepared by Reversible Addition–Fragmentation Chain Transfer Strategy, ACS Appl. Mater. Interfaces, 2014, 第 1 作者
(19) Preparation of protein imprinted materials by hierarchical imprinting techniques and application in selective depletion of albumin from human serum, Sci Rep, 2014, 第 4 作者
(20) Transferrin recognition based on a protein imprinted material prepared by hierarchical imprinting technique, Microchim. Acta, 2013, 第 2 作者
(21) Hydrophilic immobilized trypsin reactor with magnetic graphene oxide as support for high efficient proteome digestion, J. Chromatogr. A, 2012, 第 2 作者
(22) Protein Imprinted Materials: Rational Design, Application and Challenges, Analytical and Bioanalytical Chemistry, 2012, 第 1 作者
(23) Preparing a metal-ion chelated immobilized enzyme reactor based on the polyacrylamide monolith grafted with polyethylenimine for a facile regeneration and high throughput tryptic digestion in proteomics, Analytical and Bioanalytical Chemistry, 2012, 通讯作者
(24) Boronic acid functionalized core-shell polymer nanoparticles for selective enrichment of glycopeptides, Chemistry - A European Journal, 2012, 第 3 作者
(25) A novel organic-inorganic hybrid monolith for trypsin immobilization, Sci. China-Life Sci., 2011, 第 3 作者
(26) Urea free and more efficient sample preparation method for mass spectrometry based protein identification via combining the formic acid-assisted chemical cleavage and trypsin digestion, Talanta, 2011, 通讯作者
(27) Preparation of a new type of affinity materials combining metal coordination with molecular imprinting, Chemical Communications, 2011, 第 2 作者
(28) Macroporous molecularly imprinted monolithic polymer columns for protein recognition by liquid chromatography, Journal of separation science, 2010, 第 3 作者
(29) Self-Assembly Molecularly Imprinted Nanofiber for 4-HA Recognition, Analytical Letters, 2010, 第 3 作者
(30) One-Pot Synthesis of Hydrophilic Molecularly Imprinted Nanoparticles, Macromolecules, 2009, 第 1 作者
(31) Molecularly imprinted porous polysulfone particles for the binding and recognition of bisphenol A, Desalination, 2009, 第 1 作者
(32) BPA transfer rate increase using molecular imprinted polyethersulfone hollow fiber membrane., J. Membr. Sci., 2008, 第 4 作者
(33) Effect of the template molecules and nonsolvent additives on the recognition property of molecular imprinted polyethersulforte particles., J. Appl. Polym. Sci., 2008, 第 4 作者
(34) Preparation and selective binding characterization of bisphenol a imprinted polyethersulfone particles, J. Appl. Polym. Sci., 2007, 第 1 作者
(35) DNA-loaded porous polyethersulfone particles for environmental applications I. Preparation, J. Appl. Polym. Sci., 2005, 第 3 作者
(36) DNA-loaded porous polyethersulfone particles for environmental applications II. Utilization, J. Appl. Polym. Sci., 2005, 第 2 作者
(37) Characterization of DNA-loaded porous polyethersulfone particles prepared by phase inversion technique., Colloid Journal, 2005, 第 2 作者
(38) Molecularly imprinted polyethersulfone microspheres for the binding and recognition of bisphenol A, Anal. Chim. Acta, 2005, 第 1 作者
(39) Preparation of DNA-encapsulated polyethersulfone hollow microspheres for organic compounds and heavy metal ions removal, Desalination, 2005, 第 1 作者
(40) DNA-modified porous polysulfone microspheres for selective removal of endocrine disruptors, Chemical Journal of Chinese Universities-Chinese, 2005, 第 2 作者
(41) Preparation of DNA hybrid polyethersulfone microspheres for endocrine disruptor removal, Key Engineering Materials, 2005, 第 2 作者
(42) DNA-immobilized porous polysulfone beads for organic compounds and heavy metal ion removal., Desalination, 2004, 第 2 作者
(43) Preparation of porous polysulfone beads for selective removal of endocrine disruptors, Separation and Purification Technology, 2004, 第 3 作者
Research Interests
New techniques and methods of proteomics; Novel Materials for protein enrichment and separation; Molecular imprinting; Cancer; Precision Medicine; Bioenergy