基本信息
杨开广 男 博导 中国科学院大连化学物理研究所
电子邮件： yangkaiguang@dicp.ac.cn
通信地址： 辽宁省大连市中山路457号 大连化物所1810组
邮政编码： 116023
电子邮件： yangkaiguang@dicp.ac.cn
通信地址： 辽宁省大连市中山路457号 大连化物所1810组
邮政编码： 116023
研究领域
蛋白质组学新技术新方法；功能材料；载体交联；蛋白质复合物原位分析
教育背景
2007-09--2009-02 Lund University 联合培养博士生2003-09--2009-06 四川大学 博士1999-09--2003-06 成都理工大学 学士
专利与奖励
专利：
已授权发明专利103项。
获奖：
中国科学院“青年创新促进会”优秀会员（2022年）
大连化物所“张大煜青年学者”（2022年）
大连化物所冠名奖“青年优秀奖” （2016年）
代表性专利成果：
（ 1 ） 一种聚乙二醇偶联结合超滤离心分离富集糖肽的方法, 发明, 2011, 专利号: 201110104461.X
（ 2 ） 一种亲水性金属离子固定化亲和纳米磁球的制备方法, 发明, 2011, 专利号: 201110103667.0
（ 3 ） 多种蛋白质肽段同时印迹聚合物微球材料及其制备和应用, 发明, 2016, 专利号: 201310240284.7
（ 4 ） 基于RAFT策略蛋白质表面分子印迹材料及制备和应用, 发明, 2016, 专利号: 201310240303.6
（ 5 ） 一种生物样品纯化的装置及其应用, 发明, 2017, 专利号: 201310237476.2
（ 6 ） 一种聚合物纳米微球的制备方法, 发明, 2017, 专利号: 201410040748.4
（ 7 ） 一种核壳结构的聚合物微球及其制备和应用, 发明, 2018, 专利号: 201410749219.1
（ 8 ） 一种有机无机杂化微球颗粒及其制备和应用, 发明, 2018, 专利号: 201410748234.4
（ 9 ） 基于质谱的氧连接氮乙酰葡糖胺修饰糖蛋白质的分析方法, 发明, 2019, 专利号: 201410397766.8
（ 10 ） 赖氨酸氮连接磷酸化翻译后修饰富集和鉴定的方法, 发明, 2019, 专利号: 201610396820.6
出版信息
申请人已在Nature Communications, Advanced Materials, Science Bulletin, Small, Anal. Chem.，ACS Appl. Mater.Interfaces，Nanoscale，Macromolecules，Chem. Commun.，等杂志发表SCI 文章104余篇，他引2700 余次，H 因子34(截至2024年5月24日)。
发表论文
[1] Chen, Yuwan, Zhou, Wen, Xia, Yufei, Zhang, Weijie, Zhao, Qun, Li, Xinwei, Gao, Hang, Liang, Zhen, Ma, Guanghui, Yang, Kaiguang, Zhang, Lihua, Zhang, Yukui. Targeted cross-linker delivery for the in situ mapping of protein conformations and interactions in mitochondria. NATURE COMMUNICATIONS[J]. 2023, 第 10 作者 通讯作者 14(1): http://dx.doi.org/10.1038/s41467-023-39485-3.[2] Li, Xinwei, Chen, Yuwan, Jiang, Jing, Zhou, Wen, Gao, Hang, Zhao, Qun, Liang, Zhen, Cao, Xupeng, Yang, Kaiguang, Zhang, Lihua, Zhang, Yukui. Crosslinker Nanocarriers Delivery to Chloroplasts for In Vivo Mapping of Photosynthetic Membrane Protein Complexes in Living Chlamydomonas reinhardtii Cells. ANALYTICAL CHEMISTRY. 2023, 第 9 作者 通讯作者 http://dx.doi.org/10.1021/acs.analchem.3c01009.[3] Ma, Baofu, Zhang, Kun, Sun, Zhen, Pan, Hui, Yang, Kaiguang, Jiang, Bo, Zhao, Baofeng, Liang, Zhen, Zhang, Yukui, Zhang, Lihua. Pushpin-like nanozyme for plasmon-enhanced tumor targeted therapy. ACTA BIOMATERIALIA[J]. 2023, 第 5 作者158: 673-685, http://dx.doi.org/10.1016/j.actbio.2022.12.069.[4] Zhou, Wen, Sui, Zhigang, Liu, Jianhui, He, Yingyun, Yuan, Huiming, Sun, Yue, Liang, Zhen, Yang, Kaiguang, Zhang, Lihua, Zhang, Yukui. High-Sensitivity Detection toward SARS-CoV-2 S1 Glycoprotein by Parallel Reaction Monitoring Mass Spectrometry. ANALYTICAL CHEMISTRY[J]. 2023, 第 8 作者 通讯作者 95(23): 8752-8757, http://dx.doi.org/10.1021/acs.analchem.2c05770.[5] Liu, Lukuan, Liu, Jianhui, Zhou, Wen, Sui, Zhigang, Liu, Jing, Yang, Kaiguang, Zhang, Lihua, Liang, Zhen, Zhang, Yukui. An artificial antibody for exosome capture by dull template imprinting technology. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2022, 第 6 作者 通讯作者 10(35): 6655-6663, http://dx.doi.org/10.1039/d2tb00494a.[6] Chu, Hongwei, Zhao, Qun, Liu, Ju, Yang, Kaiguang, Wang, Yanlei, Liu, Jianhui, Zhang, Kun, Zhao, Baofeng, He, Hongyan, Zheng, Yong, Zhong, Shijun, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. Ionic Liquid-Based Extraction System for In-Depth Analysis of Membrane Protein Complexes. ANALYTICAL CHEMISTRY[J]. 2022, 第 4 作者94(2): 758-767, http://dx.doi.org/10.1021/acs.analchem.1c03195.[7] 周雯, 杨开广, 张丽华, 梁振, 张玉奎. 基于成簇的规则间隔短回文重复序列的严重急性呼吸综合征冠状病毒2检测的最新进展. 色谱[J]. 2022, 第 2 作者40(9): 773-781, http://lib.cqvip.com/Qikan/Article/Detail?id=7108017435.[8] Wang, ZiXuan, Chu, HongWei, Yang, KaiGuang, Zhao, BaoFeng, Liang, Zhen, Zhang, LiHua, Zhang, YuKui. Label-Free Quantitative Proteomics Analysis of the Sorafenib Resistance in HepG2 Cells. JOURNAL OF ANALYSIS AND TESTING. 2021, 第 3 作者[9] Li, Yilan, Yang, Kaiguang, Yuan, Huiming, Zhang, Weijie, Sui, Zhigang, Wang, Nan, Lin, Hongli, Zhang, Lihua, Zhang, Yukui. Surface Nanosieving Polyether Sulfone Particles with Graphene Oxide Encapsulation for the Negative Isolation toward Extracellular Vesicles. ANALYTICAL CHEMISTRY[J]. 2021, 第 2 作者93(50): 16835-16844, [10] 周雯, 杨开广, 赵宝锋, 张丽华, 张玉奎. 活性氧刺激响应纳米载体. 色谱[J]. 2021, 第 2 作者39(2): 118-124, http://lib.cqvip.com/Qikan/Article/Detail?id=7103766298.[11] Chu, Hongwei, Zhao, Qun, Liu, Ju, Yang, Kaiguang, Wang, Yanlei, Liu, Jianhui, Zhang, Kun, Zhao, Baofeng, He, Hongyan, Zheng, Yong, Zhong, Shijun, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. Ionic Liquid-Based Extraction System for In-Depth Analysis of Membrane Protein Complexes. ANALYTICAL CHEMISTRY[J]. 2021, 第 4 作者[12] Hu, Yechen, Jiang, Hao, Zhao, Baofeng, Yang, Kaiguang, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. Quantitative proteomics of epigenetic histone modifications in MCF-7 cells under estradiol stimulation. ANALYTICAL METHODS[J]. 2021, 第 4 作者13(4): 469-476, http://dx.doi.org/10.1039/d0ay02146f.[13] Deng, Nan, Chen, Yuanbo, Liang, Zhen, Bian, Yangyang, Wang, Bing, Sui, Zhigang, Zhang, Xiaodan, Yang, Kaiguang, Zhang, Lihua, Zhang, Yukui. Ampholine immobilized polymer microspheres for increasing coverage of human urinary proteome. TALANTA[J]. 2020, 第 8 作者215: http://dx.doi.org/10.1016/j.talanta.2020.120931.[14] Sun, Mingwei, Liang, Yu, Li, Yang, Yang, Kaiguang, Zhao, Baofeng, Yuan, Huiming, Li, Xiao, Zhang, Xiaodan, Liang, Zhen, Shan, Yichu, Zhang, Lihua, Zhang, Yukui. Comprehensive Analysis of Protein N-Terminome by Guanidination of Terminal Amines. ANALYTICAL CHEMISTRY[J]. 2020, 第 4 作者92(1): 567-572, https://www.webofscience.com/wos/woscc/full-record/WOS:000506719400033.[15] 周雯, 杨开广, 赵宝锋, 张丽华, 张玉奎. 活性氧刺激响应纳米载体. 色谱. 2020, 第 2 作者118-124, https://nxgp.cnki.net/kcms/detail?v=3uoqIhG8C46NmWw7YpEsKMypi3qVj28LEUDxQXHYyS3fbyEOrIfBzJ9ZGvXuXMTJdt94RmuLHeRHLJC-FkxMhZc1qMGXZOlM&uniplatform=NZKPT.[16] Lukuan Liu, Chengyong Dong, Xinwei Li, Senwu Li, Baofu Ma, Baofeng Zhao, Xiao Li, Zhen Liang, Kaiguang Yang, Lihua Zhang, Yukui Zhang. Antibody‐Free Hydrogel with the Synergistic Effect of Cell Imprinting and Boronate Affinity: Toward the Selective Capture and Release of Undamaged Circulating Tumor Cells. Small[J]. 2020, 第 9 作者 通讯作者 16(7): https://www.doi.org/10.1002/smll.201904199.[17] Yang, Kaiguang, Li, Senwu, Liu, Lukuan, Chen, Yuwan, Zhou, Wen, Pei, Jiaqi, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. Epitope Imprinting Technology: Progress, Applications, and Perspectives toward Artificial Antibodies. ADVANCED MATERIALS[J]. 2019, 第 1 作者31(50): https://www.webofscience.com/wos/woscc/full-record/WOS:000481819300001.[18] Liu, Lukuan, Yang, Kaiguang, Li, Senwu, Zhang, Lihua, Zhang, Yukui. Poly(ether sulfone) nanoparticles and controllably modified nanoparticles obtained through temperature-dependent cryogelation. JOURNAL OF APPLIED POLYMER SCIENCE[J]. 2019, 第 2 作者136(20): http://www.corc.org.cn/handle/1471x/2372793.[19] Liang, Yantao, Wang, Long, Wang, Zengmeng, Zhao, Jiulong, Yang, Qingwei, Wang, Min, Yang, Kaiguang, Zhang, Lihua, Jiao, Nianzhi, Zhang, Yongyu. Metagenomic Analysis of the Diversity of DNA Viruses in the Surface and Deep Sea of the South China Sea. FRONTIERS IN MICROBIOLOGY[J]. 2019, 第 7 作者10: https://doaj.org/article/9559b54a7d8f44b69ae50aaa07a607f7.[20] Liu, Lukuan, Yang, Kaiguang, Gao, Hang, Li, Xiao, Chen, Yuanbo, Zhang, Lihua, Peng, Xiaojun, Zhang, Yukui. Artificial Antibody with Site-Enhanced Multivalent Aptamers for Specific Capture of Circulating Tumor Cells. ANALYTICAL CHEMISTRY[J]. 2019, 第 2 作者91(4): 2591-2594, http://cas-ir.dicp.ac.cn/handle/321008/165976.[21] 杨开广, 李森武, 刘路宽, 陈玉宛, 周雯, 张丽华, 张玉奎. 抗原决定基印迹材料及其应用. 科学通报[J]. 2019, 第 1 作者1368-1379, https://www.sciengine.com/doi/10.1360/N972018-01033.[22] 刘路宽, 杨开广, 梁振, 张丽华, 张玉奎. 循环肿瘤细胞捕获方法的研究进展. 色谱[J]. 2019, 第 2 作者37(4): 358-366, http://lib.cqvip.com/Qikan/Article/Detail?id=7001511997.[23] Liu, Lukuan, Yang, Kaiguang, Dai, Zhongpeng, Liang, Zhen, Zhang, Lihua, Peng, Xiaojun, Zhang, Yukui. Cell-imprinted polydimethylsiloxane for the selective cell adhesion. CHINESE CHEMICAL LETTERS[J]. 2019, 第 2 作者30(3): 672-675, http://lib.cqvip.com/Qikan/Article/Detail?id=7001849614.[24] Hou, Rui, Li, Yilan, Sui, Zhigang, Yuan, Huiming, Yang, Kaiguang, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. Advances in exosome isolation methods and their applications in proteomic analysis of biological samples. ANALYTICAL AND BIOANALYTICAL CHEMISTRY. 2019, 第 5 作者411(21): 5351-5361, [25] Lukuan Liu, Kaiguang Yang, Zhongpeng Dai, Zhen Liang, Lihua Zhang, Xiaojun Peng, Yukui Zhang. Cell-imprinted polydimethylsiloxane for the selective cell adhesion. 中国化学快报:英文版[J]. 2019, 第 2 作者30(3): 672-675, http://lib.cqvip.com/Qikan/Article/Detail?id=7001849614.[26] Wu, Qiong, Jiang, Bo, Weng, Yejing, Liu, Jianxi, Li, Senwu, Hu, Yechen, Yang, Kaiguang, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. 3-Carboxybenzoboroxole Functionalized Polyethylenimine Modified Magnetic Graphene Oxide Nanocomposites for Human Plasma Glycoproteins Enrichment under Physiological Conditions. ANALYTICAL CHEMISTRY[J]. 2018, 第 7 作者90(4): 2671-2677, http://cas-ir.dicp.ac.cn/handle/321008/168820.[27] Han, Shuai, Yang, Kaiguang, Zhu, Hong, Liu, Jianhui, Zhang, Lihua, Zhao, Jiuyang. Proteomics investigation of the changes in serum proteins after high- and low-flux hemodialysis. RENAL FAILURE[J]. 2018, 第 2 作者40(1): 506-513, http://cas-ir.dicp.ac.cn/handle/321008/166966.[28] Li, Senwu, Yang, Kaiguang, Liu, Lukuan, Zhao, Baofeng, Chen, Yuanbo, Li, Xiao, Zhang, Lihua, Zhang, Yukui. Surface sieving coordinated IMAC material for purification of His-tagged proteins. ANALYTICA CHIMICA ACTA[J]. 2018, 第 2 作者997: 9-15, http://dx.doi.org/10.1016/j.aca.2017.10.021.[29] Shao, Wenya, Liu, Jianxi, Liang, Yu, Yang, Kaiguang, Min, Yi, Zhang, Xiaodan, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. "Thiol-ene" grafting of silica particles with three-dimensional branched copolymer for HILIC/cation-exchange chromatographic separation and N-glycopeptide enrichment. ANALYTICAL AND BIOANALYTICAL CHEMISTRY[J]. 2018, 第 4 作者410(3): 1019-1027, http://cas-ir.dicp.ac.cn/handle/321008/168532.[30] Liu, Lukuan, Yang, Kaiguang, Zhu, Xudong, Liang, Yu, Chen, Yuanbo, Fang, Fei, Zhao, Qun, Zhang, Lihua, Zhang, Yukui. Aptamer-immobilized open tubular capillary column to capture circulating tumor cells for proteome analysis. TALANTA[J]. 2017, 第 2 作者175: 189-193, http://dx.doi.org/10.1016/j.talanta.2017.07.041.[31] Yang, Kaiguang, Liu, Jianhui, Sun, Jingdi, Zhou, Yuan, Zhao, Qun, Li, Senwu, Liu, Lukuan, Zhang, Lihua, Zhao, Jiuyang, Zhang, Yukui. Proteomic study provides new clues for complications of hemodialysis caused by dialysis membrane. SCIENCE BULLETIN[J]. 2017, 第 1 作者62(18): 1251-1255, http://dx.doi.org/10.1016/j.scib.2017.08.026.[32] Han, Shuai, Yang, Kaiguang, Sun, Jingdi, Liu, Jianhui, Zhang, Lihua, Zhao, Jiuyang. Proteomics Investigations into Serum Proteins Adsorbed by High-Flux and Low-Flux Dialysis Membranes. PROTEOMICS CLINICAL APPLICATIONS[J]. 2017, 第 2 作者11(11-12): http://cas-ir.dicp.ac.cn/handle/321008/168442.[33] Chen, Yuanbo, Deng, Nan, Wu, Ci, Liang, Yu, Jiang, Bo, Yang, Kaiguang, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. Aptamer functionalized hydrophilic polymer monolith with gold nanoparticles modification for the sensitive detection of human alpha-thrombin. TALANTA[J]. 2016, 第 6 作者154: 555-559, http://cas-ir.dicp.ac.cn/handle/321008/170974.[34] Li, Senwu, Yang, Kaiguang, Zhao, Baofeng, Li, Xiao, Liu, Lukuan, Chen, Yuanbo, Zhang, Lihua, Zhang, Yukui. Epitope imprinting enhanced IMAC (EI-IMAC) for highly selective purification of His-tagged protein (vol 4, pg 1960, 2016). JOURNAL OF MATERIALS CHEMISTRY B. 2016, 第 2 作者4(15): 2739-2739, http://cas-ir.dicp.ac.cn/handle/321008/170734.[35] Li, Senwu, Yang, Kaiguang, Deng, Nan, Min, Yi, Liu, Lukuan, Zhang, Lihua, Zhang, Yukui. Thermoresponsive Epitope Surface-Imprinted Nanoparticles for Specific Capture and Release of Target Protein from Human Plasma. ACS APPLIED MATERIALS & INTERFACES[J]. 2016, 第 2 作者8(9): 5747-5751, http://cas-ir.dicp.ac.cn/handle/321008/148410.[36] Shao, Wenya, Liu, Jianxi, Yang, Kaiguang, Liang, Yu, Weng, Yejing, Li, Senwu, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. Hydrogen-bond interaction assisted branched copolymer HILIC material for separation and N-glycopeptides enrichment. TALANTA[J]. 2016, 第 3 作者158: 361-367, http://dx.doi.org/10.1016/j.talanta.2016.05.034.[37] Liu, Jianxi, Yang, Kaiguang, Shao, Wenya, Qu, Yanyan, Li, Senwu, Wu, Qi, Zhang, Lihua, Zhang, Yukui. Boronic Acid-Functionalized Particles with Flexible Three-Dimensional Polymer Branch for Highly Specific Recognition of Glycoproteins. ACS APPLIED MATERIALS & INTERFACES[J]. 2016, 第 2 作者8(15): 9552-9556, http://dx.doi.org/10.1021/acsami.6b01829.[38] Wu, Ci, Liang, Yu, Yang, Kaiguang, Min, Yi, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. Clickable Periodic Mesoporous Organosilica Monolith for Highly Efficient Capillary Chromatographic Separation. ANALYTICAL CHEMISTRY[J]. 2016, 第 3 作者88(3): 1521-1525, http://cas-ir.dicp.ac.cn/handle/321008/148420.[39] Liu, Lukuan, Yang, Kaiguang, Zhang, Lihua, Zhang, Yukui. Protein-imprinted material for the treatment of antibiotic-resistant bacteria. SCIENCE BULLETIN[J]. 2016, 第 2 作者61(24): 1890-1891, http://dx.doi.org/10.1007/s11434-016-1207-7.[40] Nan Deng, Bo Jiang, Yuanbo Chen, Zhen Liang, Lihua Zhang, Yu Liang, Kaiguang Yang, Yukui Zhang. Aptamer-conjugated gold functionalized graphene oxide nanocomposites for human α-thrombin specific recognition. JOURNAL OF CHROMATOGRAPHY A. 2016, 第 7 作者1427: 16-21, http://dx.doi.org/10.1016/j.chroma.2015.12.018.[41] Deng, Nan, Jiang, Bo, Chen, Yuanbo, Liang, Zhen, Zhang, Lihua, Liang, Yu, Yang, Kaiguang, Zhang, Yukui. Aptamer-conjugated gold functionalized graphene oxide nanocomposites for human alpha-thrombin specific recognition. JOURNAL OF CHROMATOGRAPHY A[J]. 2016, 第 7 作者1427: 16-21, http://cas-ir.dicp.ac.cn/handle/321008/148426.[42] Fang, Fei, Zhao, Qun, Sui, Zhigang, Liang, Yu, Jiang, Hao, Yang, Kaiguang, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. Glycan Moieties as Bait to Fish Plasma Membrane Proteins. ANALYTICAL CHEMISTRY[J]. 2016, 第 6 作者88(10): 5065-5071, http://dx.doi.org/10.1021/acs.analchem.6b01082.[43] Yang, Kaiguang, Li, Senwu, Liu, Jianxi, Liu, Lukuan, Zhang, Lihua, Zhang, Yukui. Multiepitope Templates Imprinted Particles for the Simultaneous Capture of Various Target Proteins. ANALYTICAL CHEMISTRY[J]. 2016, 第 1 作者88(11): 5621-5625, http://dx.doi.org/10.1021/acs.analchem.6b01247.[44] 李沁然, 杨开广, 梁玉, 江波, 刘健熙, 张丽华, 梁振, 张玉奎. Surface Protein Imprinted Core−Shell Particles for High Selective. ACS APPLIED MATERIALS & INTERFACES[J]. 2016, 第 2 作者6: 21954, http://cas-ir.dicp.ac.cn/handle/321008/148325.[45] Li, Senwu, Yang, Kaiguang, Zhao, Baofeng, Li, Xiao, Liu, Lukuan, Chen, Yuanbo, Zhang, Lihua, Zhang, Yukui. Epitope imprinting enhanced IMAC (EI-IMAC) for highly selective purification of His-tagged protein. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2016, 第 2 作者4(11): 1960-1967, http://cas-ir.dicp.ac.cn/handle/321008/148415.[46] Li, Qinran, Yang, Kaiguang, Li, Senwu, Liu, Lukuan, Zhang, Lihua, Liang, Zhen, Zhang, Yukui. Preparation of surface imprinted core-shell particles via a metal chelating strategy: specific recognition of porcine serum albumin. MICROCHIMICA ACTA[J]. 2016, 第 2 作者183(1): 345-352, http://cas-ir.dicp.ac.cn/handle/321008/148438.[47] 陈远波, 邓楠, 吴慈, 梁玉, 江波, 杨开广, 梁振, 张丽华, 张玉奎. Aptamer Functionalized Hydrophilic Polymer Monolith with Gold Nanoparticles Modification for Zhodification for the Sensitive Detection of Human Alpha-thrombin. TALANTA[J]. 2016, 第 6 作者154: 555, http://cas-ir.dicp.ac.cn/handle/321008/148423.[48] Liu, Jianxi, Yang, Kaiguang, Shao, Wenya, Li, Senwu, Wu, Qi, Zhang, Shen, Qu, Yanyan, Zhang, Lihua, Zhang, Yukui. Synthesis of Zwitterionic Polymer Particles via Combined Distillation Precipitation Polymerization and Click Chemistry for Highly Efficient Enrichment of Glycopeptide. ACS APPLIED MATERIALS & INTERFACES[J]. 2016, 第 2 作者8(34): 22018-22024, http://cas-ir.dicp.ac.cn/handle/321008/170092.[49] Weng, Yejing, Jiang, Bo, Yang, Kaiguang, Sui, Zhigang, Zhang, Lihua, Zhang, Yukui. Polyethyleneimine-modified graphene oxide nanocomposites for effective protein functionalization. NANOSCALE[J]. 2015, 第 3 作者7(34): 14284-14291, http://cas-ir.dicp.ac.cn/handle/321008/143725.[50] Wu, Shuaibin, Zhang, Hongfei, Yang, Kaiguang, Ma, Junfeng, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. A rapid protein sample preparation method based on organic-aqueous microwave irradiation technique. SCIENCE CHINA. CHEMISTRY[J]. 2015, 第 3 作者58(3): 526-531, http://159.226.238.44/handle/321008/143707.[51] Qu, Yanyan, Liu, Jianxi, Yang, Kaiguang, Wu, Qi, Shan, Yichu, Zhang, Lihua, Liang, Zhen, Zhang, Yukui. Glycoprotein recognition by water-compatible core-shell polymeric submicron particles. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2015, 第 3 作者3(19): 3927-3930, http://159.226.238.44/handle/321008/143714.[52] Min, Yi, Yang, Kaiguang, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. Dandelion-like core-shell silica microspheres with hierarchical pores. RSC ADVANCES[J]. 2015, 第 2 作者5(33): 26269-26272, http://159.226.238.44/handle/321008/143711.[53] Liu, Jianxi, Yang, Kaiguang, Qu, Yanyan, Li, Senwu, Wu, Qi, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. An efficient approach to prepare boronate core-shell polymer nanoparticles for glycoprotein recognition via combined distillation precipitation polymerization and RAFT media precipitation polymerization. CHEMICAL COMMUNICATIONS[J]. 2015, 第 2 作者51(18): 3896-3898, http://159.226.238.44/handle/321008/143717.[54] Li, Senwu, Yang, Kaiguang, Liu, Jianxi, Jiang, Bo, Zhang, Lihua, Zhang, Yukui. Surface-Imprinted Nanoparticles Prepared with a His-Tag-Anchored Epitope as the Template. ANALYTICAL CHEMISTRY[J]. 2015, 第 2 作者87(9): 4617-4620, http://159.226.238.44/handle/321008/143715.[55] Jiang, Bo, Yang, Kaiguang, Zhang, Lihua, Liang, Zhen, Peng, Xiaojun, Zhang, Yukui. Dendrimer-grafted graphene oxide nanosheets as novel support for trypsin immobilization to achieve fast on-plate digestion of proteins. TALANTA[J]. 2014, 第 2 作者122: 278-284, http://dx.doi.org/10.1016/j.talanta.2014.01.056.[56] Yang, Kaiguang, Liu, Jianxi, Li, Senwu, Li, Qinran, Wu, Qi, Zhou, Yuan, Zhao, Qun, Deng, Nan, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. Epitope imprinted polyethersulfone beads by self-assembly for target protein capture from the plasma proteome. CHEMICAL COMMUNICATIONS[J]. 2014, 第 1 作者50(67): 9521-9524, http://cas-ir.dicp.ac.cn/handle/321008/144465.[57] 李森武, 杨开广, 张丽华, 张玉奎. His-tag as an anchor for epitope-oriented surface imprinting. the 8th international conference on molecular imprinting. 2014, 第 2 作者http://cas-ir.dicp.ac.cn/handle/321008/143644.[58] Li, Qinran, Yang, Kaiguang, Liang, Yu, Jiang, Bo, Liu, Jianxi, Zhang, Lihua, Liang, Zhen, Zhang, Yukui. Surface Protein Imprinted Core-Shell Particles for High Selective Lysozyme Recognition Prepared by Reversible Addition-Fragmentation Chain Transfer Strategy. ACS APPLIED MATERIALS & INTERFACES[J]. 2014, 第 2 作者6(24): 21954-21960, http://cas-ir.dicp.ac.cn/handle/321008/145522.[59] 刘健熙, 杨开广, 张丽华, 张玉奎. HYDROPHILIC BORONIC ACID FUNCTIONAL CORE-SHELL PARTICLES FOR PH-RESPONSIVE RECOGNITION OF GLYCOPROTEINS BASED ON ‘THIOL-ENE’ CHEMISTRY. 30th International Symposium on Microscale Bioseparations. 2014, 第 2 作者http://cas-ir.dicp.ac.cn/handle/321008/143650.[60] 江波, 杨开广, 张丽华, 梁振, 张玉奎. CONTROL SYNTHESIS OF GO/FE3O4/AU/PEG COMPOSITES FOR THE HIGHLY SELECTIVE ENRICHMENT OF N-LINKED GLYCOPEPTIDES FROM BIOLOGICAL SAMPLES. 30th international symposium on microscale bioseparations. 2014, 第 2 作者http://cas-ir.dicp.ac.cn/handle/321008/143651.[61] 杨开广, 刘健熙, 李森武, 李沁然, 吴琪, 张丽华, 张玉奎. Protein imprinted materials for the target protein capture in human plasma proteome. the 8th international conference on molecular imprinting. 2014, 第 1 作者http://cas-ir.dicp.ac.cn/handle/321008/143645.[62] 杨开广, 李森武, 张丽华, 张玉奎. Protein imprinted materials in the proteomics study. the 8th international conference on molecular imprinting. 2014, 第 1 作者http://cas-ir.dicp.ac.cn/handle/321008/143646.[63] Liu, Jinxiang, Deng, Qiliang, Tao, Dingyin, Yang, Kaiguang, Zhang, Lihua, Liang, Zhen, Zhang, Yukui. Preparation of protein imprinted materials by hierarchical imprinting techniques and application in selective depletion of albumin from human serum. SCIENTIFIC REPORTS[J]. 2014, 第 4 作者4(1): http://cas-ir.dicp.ac.cn/handle/321008/144458.[64] Liu, Jianxi, Qu, Yanyan, Yang, Kaiguang, Wu, Qi, Shan, Yichu, Zhang, Lihua, Liang, Zhen, Zhang, Yukui. Monodisperse Boronate Polymeric Particles Synthesized by a Precipitation Polymerization Strategy: Particle Formation and Glycoprotein Response from the Standpoint of the Flory-Huggins Model. ACS APPLIED MATERIALS & INTERFACES[J]. 2014, 第 3 作者6(3): 2059-2066, http://cas-ir.dicp.ac.cn/handle/321008/144460.[65] 李沁然, 杨开广, 李森武, 刘键熙, 张丽华, 梁振, 张玉奎. 可逆加成-断裂链转移策略制备可识别转铁蛋白的抗原决定基印迹微球. 色谱[J]. 2014, 第 2 作者32(10): 1029-1033, http://lib.cqvip.com/Qikan/Article/Detail?id=662825445.[66] Zhao, Qun, Fang, Fei, Liang, Yu, Yuan, Huiming, Yang, Kaiguang, Wu, Qi, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. 1-Dodecyl-3-Methylimidazolium Chloride-Assisted Sample Preparation Method for Efficient Integral Membrane Proteome Analysis. ANALYTICAL CHEMISTRY[J]. 2014, 第 5 作者86(15): 7544-7550, http://cas-ir.dicp.ac.cn/handle/321008/144459.[67] 杨开广, 李沁然, 刘晋湘, 李森武, 张丽华, 刘健熙. PROTEIN IMPRINTED MATERIALS FOR THE TARGET PROTEIN CAPTURE IN THE PROTEOMIC SAMPLE. 30th international symposium on microscale bioseparations. 2014, 第 1 作者http://cas-ir.dicp.ac.cn/handle/321008/143652.[68] Deng, Nan, Zhu, Guijie, Chen, Yuanbo, Wu, Qi, Liang, Zhen, Sui, Zhigang, Zhang, Lihua, Yang, Kaiguang, Zhang, Yukui. Decrease of dynamic range of proteins in human plasma by ampholine immobilized polymer microspheres. ANALYTICA CHIMICA ACTA[J]. 2014, 第 8 作者826: 43-50, http://dx.doi.org/10.1016/j.aca.2014.04.004.[69] Jiang, Bo, Liang, Yu, Wu, Qi, Jiang, Hao, Yang, Kaiguang, Zhang, Lihua, Liang, Zhen, Peng, Xiaojun, Zhang, Yukui. New GO-PEI-Au-L-Cys ZIC-HILIC composites: synthesis and selective enrichment of glycopeptides. NANOSCALE[J]. 2014, 第 5 作者6(11): 5616-5619, http://cas-ir.dicp.ac.cn/handle/321008/144466.[70] Deng, Nan, Liang, Zhen, Liang, Yu, Sui, Zhigang, Zhang, Liyuan, Wu, Qi, Yang, Kaiguang, Zhang, Lihua, Zhang, Yukui. Aptamer Modified Organic Inorganic Hybrid Silica Monolithic Capillary Columns for Highly Selective Recognition of Thrombin (vol 84, pg 10186, 2012). ANALYTICAL CHEMISTRY. 2013, 第 7 作者85(7): 3794-3794, https://www.webofscience.com/wos/woscc/full-record/WOS:000317173200049.[71] 江波, 杨开广, 梁振, 张丽华, 张玉奎. Boronic acid functionalized graphene oxide composites for specific recognition of N-linked glycopeptides. 22nd international symposium on glycoconjugates. 2013, 第 2 作者366, http://159.226.238.44/handle/321008/120130.[72] Li, Qinran, Yang, Kaiguang, Liu, Jinxiang, Zhang, Lihua, Liang, Zhen, Zhang, Yukui. Transferrin recognition based on a protein imprinted material prepared by hierarchical imprinting technique. MICROCHIMICA ACTA[J]. 2013, 第 2 作者180(15-16): 1379-1386, http://www.irgrid.ac.cn/handle/1471x/858176.[73] 乔晓强, 周愿, 侯春彦, 张晓丹, 杨开广, 张丽华, 张玉奎. 溴化1-丁基，3-（3-氨丙基）咪唑用于羧基衍生：潜在应用于肽段的高灵敏度质谱鉴定. 中国科学: 生命科学[J]. 2013, 第 5 作者43(1): 96, http://159.226.238.44/handle/321008/119611.[74] 刘健熙, 杨开广, 曲焱焱, 张丽华, 梁振, 张玉奎. An efficient approach to prepare boronic acid functional core-shell polymer nanoparticles for enrichment of glycoproteins viaRAFTmedia precipitation polymerization. 22nd international symposium on glycoconjugates. 2013, 第 2 作者365, http://159.226.238.44/handle/321008/120132.[75] Qiao XiaoQiang, Zhou Yuan, Hou ChunYan, Zhang XiaoDan, Yang KaiGuang, Zhang LiHua, Zhang YuKui. 1-(3-Aminopropyl)-3-butylimidazolium bromide for carboxyl group derivatization: potential applications in high sensitivity peptide identification by mass spectrometry. SCIENCE CHINA-LIFE SCIENCES[J]. 2013, 第 5 作者56(3): 240-245, http://159.226.238.44/handle/321008/137821.[76] 曲焱焱, 翁叶靖, 杨开广, 张丽华, 张丽华, 张玉奎. Tandem dimethyl and solid-phase 18O stable isotope labeling for N-glycoproteome quantitation. 22nd international symposium on glycoconjugates. 2013, 第 3 作者367, http://159.226.238.44/handle/321008/120127.[77] 杨开广, 刘建熙, 李沁然, 张丽华, 张玉奎. Protein imprinted materials for Proteomic Study. 7TH INTERNATIONAL CONFERENCE ON MOLECULARLY IMPRINTED POLYMERS SCIENCE AND TECHNOLOGY. 2012, 第 1 作者62, http://159.226.238.44/handle/321008/117085.[78] Qu Yanyan, Liu Jianxi, Yang Kaiguang, Yuan Huiming, Zhang Lihua, Liang Zhen, Zhang Yukui. Boronic Acid Functionalized Core-shell Polymer Nanoparticles for Selective Enrichment of Glycopeptides. ASIA OCEANIA HUMAN PROTEOME ORGANIZATION 6TH CONGRESS. 2012, 第 3 作者282, http://159.226.238.44/handle/321008/117093.[79] Yang, Kaiguang, Zhang, Lihua, Liang, Zhen, Zhang, Yukui. Protein-imprinted materials: rational design, application and challenges. ANALYTICAL AND BIOANALYTICAL CHEMISTRY[J]. 2012, 第 1 作者403(8): 2173-2183, http://www.irgrid.ac.cn/handle/1471x/721602.[80] Wu, Shuaibin, Zhang, Lei, Yang, Kaiguang, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. Preparing a metal-ion chelated immobilized enzyme reactor based on the polyacrylamide monolith grafted with polyethylenimine for a facile regeneration and high throughput tryptic digestion in proteomics. ANALYTICAL AND BIOANALYTICAL CHEMISTRY[J]. 2012, 第 11 作者402(2): 703-710, http://www.irgrid.ac.cn/handle/1471x/721704.[81] 曲焱焱, 刘建熙, 杨开广, 张丽华, 梁振, 张玉奎. Boronic Acid Functionalized Core-Shell Polymer Nanoparticles Prepared by Distillation Precipitation Polymerization for Selective Enrichment of Glycopeptides. 38TH INTERNATIONAL SYMPOSIUM ON HIGH PERFORMANCE LIQUID PHASE SEPARATIONS AND RELATED TECHNIQUES. 2012, 第 3 作者256, http://159.226.238.44/handle/321008/117087.[82] 张丽媛, 张丽华, 梁振, 杨开广, 张玉奎. Novel Functionalized Materials for Phosphopeptides Enrichment with Improved Selectivity and Binding Capacity. 38TH INTERNATIONAL SYMPOSIUM ON HIGH PERFORMANCE LIQUID PHASE SEPARATIONS AND RELATED TECHNIQUES. 2012, 第 4 作者274, http://159.226.238.44/handle/321008/117086.[83] Zhang, Liyuan, Liang, Zhen, Yang, Kaiguang, Xia, Simin, Wu, Qi, Zhang, Lihua, Zhang, Yukui. Mesoporous TiO2 aerogel for selective enrichment of phosphopeptides in rat liver mitochondria. ANALYTICA CHIMICA ACTA[J]. 2012, 第 3 作者729: 26-35, http://dx.doi.org/10.1016/j.aca.2012.04.005.[84] Zhang, Liyuan, Zhao, Qun, Liang, Zhen, Yang, Kaiguang, Sun, Liangliang, Zhang, Lihua, Zhang, Yukui. Synthesis of adenosine functionalized metal immobilized magnetic nanoparticles for highly selective and sensitive enrichment of phosphopeptides. CHEMICAL COMMUNICATIONS[J]. 2012, 第 4 作者48(50): 6274-6276, http://www.irgrid.ac.cn/handle/1471x/721355.[85] Deng, Nan, Liang, Zhen, Liang, Yu, Sui, Zhigang, Zhang, Liyuan, Wu, Qi, Yang, Kaiguang, Zhang, Lihua, Zhang, Yukui. Aptamer Modified Organic-Inorganic Hybrid Silica Monolithic Capillary Columns for Highly Selective Recognition of Thrombin. ANALYTICAL CHEMISTRY[J]. 2012, 第 7 作者84(23): 10186-10190, http://159.226.238.44/handle/321008/142981.[86] Jiang, Bo, Yang, Kaiguang, Zhao, Qun, Wu, Qi, Liang, Zhen, Zhang, Lihua, Peng, Xiaojun, Zhang, Yukui. Hydrophilic immobilized trypsin reactor with magnetic graphene oxide as support for high efficient proteome digestion. JOURNAL OF CHROMATOGRAPHY A[J]. 2012, 第 2 作者1254: 8-13, http://dx.doi.org/10.1016/j.chroma.2012.07.030.[87] 杨开广, 张丽华, 张玉奎. 蛋白质分离和鉴定的新技术新方法研究进展. 郑州轻工业学院学报：自然科学版[J]. 2012, 第 1 作者27(5): 1-7, http://lib.cqvip.com/Qikan/Article/Detail?id=44273370.[88] Qu, Yanyan, Liu, Jianxi, Yang, Kaiguang, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. Boronic Acid Functionalized Core-Shell Polymer Nanoparticles Prepared by Distillation Precipitation Polymerization for Glycopeptide Enrichment. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2012, 第 3 作者18(29): 9056-9062, http://www.irgrid.ac.cn/handle/1471x/721422.[89] Liu, Jinxiang, Yang, Kaiguang, Deng, Qiliang, Li, Qinran, Zhang, Lihua, Liang, Zhen, Zhang, Yukui. Preparation of a new type of affinity materials combining metal coordination with molecular imprinting. CHEMICAL COMMUNICATIONS[J]. 2011, 第 2 作者47(13): 3969-3971, http://www.irgrid.ac.cn/handle/1471x/456668.[90] Zhang, Liyuan, Wang, Hui, Liang, Zhen, Yang, Kaiguang, Zhang, Lihua, Zhang, Yukui. Facile preparation of monolithic immobilized metal affinity chromatography capillary columns for selective enrichment of phosphopeptides. JOURNAL OF SEPARATION SCIENCE[J]. 2011, 第 4 作者34(16-17): 2122-2130, http://www.irgrid.ac.cn/handle/1471x/456667.[91] 江波, 杨开广, 张丽华, 梁振, 彭小军, 张玉奎. Covalent Bonding Fe3o4 Nanoparticles on Graphene Oxide and Used as Substrate for Microwave-assisted Digestion of Protein. 37TH INTERNATIONAL SYMPOSIUM ON HIGH-PERFORMANCE LIQUID PHASE SEPARATIONS AND RELATED TECHNIQUES. 2011, 第 2 作者479, http://159.226.238.44/handle/321008/117400.[92] WU ShuaiBin, MA JunFeng, YANG KaiGuang, LIU JinXiang, LIANG Zhen, ZHANG LiHua, ZHANG YuKui. A novel organic-inorganic hybrid monolith for trypsin immobilization. 中国科学：生命科学英文版[J]. 2011, 第 3 作者54(1): 54-59, http://lib.cqvip.com/Qikan/Article/Detail?id=36441417.[93] 吴帅斌, 张磊, 杨开广, 梁振, 张丽华, 张玉奎. Rapid regeneration of metal ion chelated immobilized enzyme reactor for high throughput digestion. 37TH INTERNATIONAL SYMPOSIUM ON HIGH-PERFORMANCE LIQUID PHASE SEPARATIONS AND RELATED TECHNIQUES. 2011, 第 3 作者477, http://159.226.238.44/handle/321008/117402.[94] Sun, Liangliang, Zhao, Qun, Zhu, Guijie, Zhou, Yuan, Wang, Tingting, Shan, Yichu, Yang, Kaiguang, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. Octyl-functionalized hybrid magnetic mesoporous microspheres for enrichment of low-concentration peptides prior to direct analysis by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. RAPID COMMUNICATIONS IN MASS SPECTROMETRY[J]. 2011, 第 7 作者25(9): 1257-1265, http://www.irgrid.ac.cn/handle/1471x/456671.[95] 刘键熙, 曲焱焱, 杨开广, 吴琪, 张丽华, 张玉奎. Boronic Acid Functionalized Core-shell Polymer Nanoparticles for Selective Enrichment of Glycopeptides. 37TH INTERNATIONAL SYMPOSIUM ON HIGH-PERFORMANCE LIQUID PHASE SEPARATIONS AND RELATED TECHNIQUES. 2011, 第 3 作者402-0, http://159.226.238.44/handle/321008/116003.[96] Qiao, Xiaoqiang, Sun, Liangliang, Chen, Lingfan, Zhou, Yuan, Yang, Kaiguang, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. Piperazines for peptide carboxyl group derivatization: effect of derivatization reagents and properties of peptides on signal enhancement in matrix-assisted laser desorption/ionization mass spectrometry. RAPID COMMUNICATIONS IN MASS SPECTROMETRY[J]. 2011, 第 5 作者25(5): 639-646, http://www.irgrid.ac.cn/handle/1471x/456676.[97] 李沁然, 杨开广, 刘晋湘, 张丽华, 梁振, 张玉奎. Preparation and Application of Surface Imprintiong Particles with Metal Chelating for Recognition of Albumin. 37TH INTERNATIONAL SYMPOSIUM ON HIGH-PERFORMANCE LIQUID PHASE SEPARATIONS AND RELATED TECHNIQUES. 2011, 第 2 作者398, http://159.226.238.44/handle/321008/117408.[98] 杨开广, 刘键熙, 曲焱焱, 张丽华, 张玉奎. Preparation of epitope imprinted polyethersulfone particles through self-assembly for protein recognition. THE 11TH ASIAN CONFERENCE ON ANALYTICAL SCIENCES. 2011, 第 1 作者67, http://159.226.238.44/handle/321008/117382.[99] Wu, Shuaibin, Sun, Liangliang, Ma, Junfeng, Yang, Kaiguang, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. High throughput tryptic digestion via poly (acrylamide-co-methylenebisacrylamide) monolith based immobilized enzyme reactor. TALANTA[J]. 2011, 第 4 作者83(5): 1748-1753, http://dx.doi.org/10.1016/j.talanta.2010.12.011.[100] 杨开广, 刘键熙, 曲焱焱, 张丽华, 梁振, 张玉奎. Fabrication of Epitope Imprinted Polyethersulfone Particles through Self-assembly for Protein Recogintion. 37TH INTERNATIONAL SYMPOSIUM ON HIGH-PERFORMANCE LIQUID PHASE SEPARATIONS AND RELATED TECHNIQUES. 2011, 第 1 作者476, http://159.226.238.44/handle/321008/117403.[101] Zhang, Liyuan, Xu, Jin, Sun, Liangliang, Ma, Junfeng, Yang, Kaiguang, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. Zirconium oxide aerogel for effective enrichment of phosphopeptides with high binding capacity. ANALYTICAL AND BIOANALYTICAL CHEMISTRY[J]. 2011, 第 5 作者399(10): 3399-3405, http://www.irgrid.ac.cn/handle/1471x/456675.[102] 邓楠, 张丽华, 杨开广, 张丽华, 张玉奎. Organci-Inorganic Hybrid Silica Monolith Based Covalently Bonded Aptamer Affinity Chromatography Column for Thrombin Detection. 37TH INTERNATIONAL SYMPOSIUM ON HIGH-PERFORMANCE LIQUID PHASE SEPARATIONS AND RELATED TECHNIQUES. 2011, 第 3 作者405, http://159.226.238.44/handle/321008/117284.[103] Wu ShuaiBin, Ma JunFeng, Yang KaiGuang, Liu JinXiang, Liang Zhen, Zhang LiHua, Zhang YuKui. A novel organic-inorganic hybrid monolith for trypsin immobilization. SCIENCE CHINA-LIFE SCIENCES[J]. 2011, 第 3 作者54(1): 54-59, http://www.irgrid.ac.cn/handle/1471x/456681.[104] Wu, Shuaibin, Yang, Kaiguang, Liang, Zhen, Zhang, Lihua, Zhang, Yukui. Urea free and more efficient sample preparation method for mass spectrometry based protein identification via combining the formic acid-assisted chemical cleavage and trypsin digestion. TALANTA[J]. 2011, 第 2 作者 通讯作者 86(待补充): 429-435, http://dx.doi.org/10.1016/j.talanta.2011.08.052.[105] Liu, Jinxiang, Deng, Qiliang, Yang, Kaiguang, Zhang, Lihua, Liang, Zhen, Zhang, Yukui. Macroporous molecularly imprinted monolithic polymer columns for protein recognition by liquid chromatography. JOURNAL OF SEPARATION SCIENCE[J]. 2010, 第 3 作者33(17-18): 2757-2761, http://159.226.238.44/handle/321008/103559.[106] 杨开广, 刘晋湘, 李沁然, 梁振, 张丽华, 张玉奎. Selective Depletion of High Abundance Proteins from Human Plasma by Imprinting Techniques. mip2010: the 6th international conference on molecular imprinting. 2010, 第 1 作者附2/2, http://159.226.238.44/handle/321008/114126.[107] 吴帅宾, 马俊锋, 杨开广, 刘晋湘, 梁振, 张丽华, 张玉奎. 基于环氧功能基团的杂化硅胶固定化酶反应器. 中国科学：生命科学[J]. 2010, 第 3 作者874-879, http://lib.cqvip.com/Qikan/Article/Detail?id=35553912.[108] Cao, Fuming, Liao, Jia, Yang, Kaiguang, Bai, Pengli, Wei, Qiang, Zhao, Changsheng. Self-Assembly Molecularly Imprinted Nanofiber for 4-HA Recognition. ANALYTICAL LETTERS[J]. 2010, 第 3 作者43(17): 2790-2797, http://www.corc.org.cn/handle/1471x/1911291.[109] Yang, Kaiguang, Berg, Martin Mingarini, Zhao, Changsheng, Ye, Lei. One-Pot Synthesis of Hydrophilic Molecularly Imprinted Nanoparticles. MACROMOLECULES[J]. 2009, 第 1 作者42(22): 8739-8746, http://dx.doi.org/10.1021/ma901761z.[110] 邓启良, 刘晋湘, 杨开广, 梁振, 张丽华, 张玉奎. Molecularly imprinted macroporous monolith columns for protein separation. post-genome technologies(ifpt6). 2009, 第 3 作者377/1, http://159.226.238.44/handle/321008/113630.[111] Yang, Kaiguang, Ma, Jiaojiao, Zhou, Hui, Li, Bingquan, Yu, Binyu, Zhao, Changsheng. Molecularly imprinted porous polysulfone particles for the binding and recognition of bisphenol A. DESALINATION[J]. 2009, 第 1 作者245(1-3): 232-245, http://www.corc.org.cn/handle/1471x/1993819.[112] Yu, Binyu, Zhang, Xinlan, He, Jie, Yang, Kaiguang, Zhao, Changsheng. Effect of the template molecules and nonsolvent additives on the recognition property of molecular imprinted polyethersulforte particles. JOURNAL OF APPLIED POLYMER SCIENCE[J]. 2008, 第 4 作者108(6): 3859-3866, https://www.webofscience.com/wos/woscc/full-record/WOS:000255339200055.[113] Zhao, Changsheng, Yu, Binyu, Qian, Bosi, Wei, Qiang, Yang, Kaiguang, Zhang, Aimin. BPA transfer rate increase using molecular imprinted polyethersulfone hollow fiber membrane. JOURNAL OF MEMBRANE SCIENCE[J]. 2008, 第 5 作者310(1-2): 38-43, http://dx.doi.org/10.1016/j.memsci.2007.10.042.[114] Yang, Kaiguang, Li, Bingquan, Zhou, Hui, Ma, Jiaojiao, Bai, Pengli, Zhao, Changsheng. Preparation and selective binding characterization of bisphenol a imprinted polyethersulfone particles. JOURNAL OF APPLIED POLYMER SCIENCE[J]. 2007, 第 1 作者106(4): 2791-2799, http://www.corc.org.cn/handle/1471x/1994178.[115] Mao, M, Liu, ZB, Wang, T, Yu, BY, Wen, X, Yang, KG, Zhao, CS. 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发表著作
（1） 蛋白质组学研究-概念、技术及应用, Proteome Research--Concepts, Technology and Application, 科学出版社, 2010-05, 第 5 作者
科研活动
科研项目
（ 1 ） 用于血浆高丰度蛋白质选择性去除的多抗原决定基表面印迹磁球的研究, 主持, 国家级, 2011-01--2013-12（ 2 ） 基于相反转自组装技术的蛋白质 C-末端肽印迹材料制备及机理研究, 主持, 国家级, 2014-01--2017-12（ 3 ） 针对细胞识别的人工抗体材料制备及其在循环肿瘤细胞捕获中的应用, 主持, 国家级, 2016-01--2019-12（ 4 ） 蛋白质组富集分离与修饰鉴定的关键技术研究与开发, 参与, 国家级, 2012-01--2015-12（ 5 ） 质谱鉴定新方法研究, 参与, 国家级, 2016-07--2019-12（ 6 ） 中国科学院青年创新促进会第七批会员资助, 主持, 部委级, 2017-01--2020-12（ 7 ） 基于交联剂跨膜靶向转运载体的细胞内蛋白质复合物原位靶向分析方法, 主持, 国家级, 2019-01--2022-12