Natural Products Chemsitry, Organic Chemistry

09.2007-06.2012                           Ph.D.  Organic Chemistry

                                                       College of Chemistry and Chemical Engineering

                                                       Lanzhou University

                                                       Lanzhou, P.R. China

09.2003-06.2007                           B.Sc.  Chemistry

                                                       School of Chemistry and Chemical Engineering

                                                       Shandong University

                                                       Jinan, P.R. China

POSTDOCTORAL TRAINING:

12.2014-09.2015                            Postdoctoral Research Associate

                                                       Center for Excellence in Post-Harvest Technologies

                                                       North Carolina A&T State University

                                                       North Carolina Research Campus

                                                       Kannapolis, NC 28081, USA

03.2013-11.2014                            Postdoctoral Researcher

                                                       College of Pharmacy

                                                       Seoul National University

                                                       Seoul, Republic of Korea

09.2012-02.2013                            Postdoctoral Researcher

                                                       College of Pharmacy

                                                       Chosun University

                                                       Gwangju, Republic of Korea

ACADEMIC APPOINTMENTS:

11.2015— 12.2018                       Associate Professor

Winner of CAS Pioneer Hundred Talents Program

                                                      Lanzhou Institute of Chemical Physics, CAS

12.2018 — present                      Full Professor

1.        Xian-Hua Meng, Kai Wang, Tian Chai, Zhi-Ying Guo, Ming Zhao, Jun-Li Yang*. Ingenane and jatrophane diterpenoids from Euphorbia kansui and their antiproliferative effects, Phytochemistry, 2020, 172, 112257.

2.        Wei-Feng Wang, Jun-Li Yang*. Advances in Screening Enzyme Inhibitors by Capillary Electrophoresis. Electrophoresis, 2019, 40(16-17), 2075–2083.

3.        Yu-Zhu Ding, Wei-Feng Wang, Tian Chai, Yin Qiang, Yan-Ping Shi, Jun-Li Yang*. Ratiometric Target-Triggered Fluorescence Silicon Nanoparticles Probe for Quantitative Visulization of Tyrosinase Activity. Talanta, 2019, 197, 113-121.

4.        Wei-Feng Wang, Jun-Li Yang*, Yan-Ping Shi. Quality Evaluation of Six Bioactive Constituents in Goji Berry based on Capillary Electrophoresis Field Amplified Sample Stacking. Electrophoresis, 2018, 39(16), 2117-2124.

5.        Wei-Feng Wang, Yin Qiang, Xian-Hua Meng, Jun-Li Yang*, Yan-Ping Shi. Ultrasensitive Colorimetric Assay Melamine based on in situ Reduction to Formation of CQDs-Silver Nanocomposite. Sensors and Actuators B: Chemical, 2018, 260, 808-815.

6.        Jun Wang, Jun-Li Yang,* Pan-Pan Zhou, Xian-Hua Meng, Yan-Ping Shi. Further New Gypenosides from Jiaogulan (Gynostemma pentaphyllum). Journal of Agricultural and Food Chemistry, 2017, 65(29), 5926–5934.

7.        Yin Qiang, Wei-Feng Wang, Basanta Dhodary, Jun-Li Yang*. Zeolitic Imidazolate Framework 8 (Zif-8) Reinforced Macroporous Resin D101 for Selective Solid-Phase Extraction of 1-Naphthol and 2-Naphthol from Phenol Compounds. Electrophoresis, 2017, 38(13-14), 1685–1692.

8.        Jun Wang, Ming Zhao, Xiang Cheng, Ying Han, Tong Zhao, Ming Fan, Lingling Zhu,* Jun-Li Yang,* Dammarane-Type Saponins from Gynostemma pentaphyllum prevent hypoxia-induced neural injury through activation of ERK, Akt and CREB pathways, Journal of Agricultural and Food Chemistry, 2020, 68, 1, 193-205.

9.        Jun Wang, Thi Kim Quy Ha, Yan-Ping Shi, Won Keun Oh*, Jun-Li Yang*, Hypoglycemic Triterpenes from Gynostemma pentaphyllum. Phytochemistry, 2018, 155, 171-181.

10.    Xuan Qi, Wei-Feng Wang, Jun Wang, Jun-Li Yang *, Yan-Ping Shi *. Highly Selective Colorimetric Detection of Putrescine in Fish Products Using O-Phthalaldehyde Derivatization Reaction. Food Chemistry, 2018, 259, 245-250.

11.    Xian-Fei Zhang, Juan Chen, Jun-Li Yang*, Yan-Ping Shi*. UPLC-MS/MS Analysis for Antioxidant Components of Lycii Fructus based on Spectrum-effect Relationship. Talanta, 2018, 180, 389-395.

12.    Lei-Lei Liu, Thi Kim Quy Ha, Wei Ha, Won Keun Oh, Jun-Li Yang*, Yan-Ping Shi*. Sesquiterpenoids with Various Carbocyclic Skeletons from the Flowers of Chrysanthemum indicum. Journal of Natural Products, 2017, 80 (2), 298–307.

13.    Junli Yang, Pei Wang, Wenbin Wu, Yantao Zhao, Emmanuel Idehen, Shengmin Sang*. Steroidal Saponins in Oat Bran. Journal of Agricultural and Food Chemistry, 2016, 64(7), 1549-1556.

14.    Jun-Li Yang, Thi Kim Quy Ha, Basanta Dhodary, Kuk-Hwa Kim, Junsoo Park, Chul-Ho Lee, Young-Choong Kim, Won Keun Oh*. Dammarane Triterpenes as Potential SIRT1 Activators from the Leaves of Panax Ginseng. Journal of Natural Products, 2014, 77(7), 1615-1623.

15.    Jun-Li Yang, Yan-Ping Shi*. Cycloartane-type Triterpenoids and Sesquiterpenoids from the Resinous Eudates ofCommiphora opobalsamum. Phytochemistry, 2012, 76, 124-132.

16.    Jun-Li Yang, Thi Kim Quy Ha, Basanta Dhodary, Euisun Pyo, Ngoc Hieu Nguyen, Hyomoon Cho, Eunhee Kim, Won Keun Oh*. Oleanane Triterpenes from the Flowers of Camellia japonica Inhibit Porcine Epidemic Diarrhea Virus (PEDV) Replication. Journal of Medicinal Chemistry, 2015, 58(3), 1268-1280.

1. New analytical methods for rapid discovery of bioactive natural compounds from herbs.

2. Purification and structure determination of bioactive components from herbs.

3. New lead compounds construction based on natural compounds.

已指导学生

祁轩  硕士研究生  070303-有机化学  

王君  博士研究生  070302-分析化学  

现指导学生

李彩虹  硕士研究生  070302-分析化学  

马丽梅  硕士研究生  070302-分析化学  

陶璐瑶  硕士研究生  085235-制药工程  

丁玉竹  博士研究生  070302-分析化学  

马丽  硕士研究生  070302-分析化学  

王凯  博士研究生  070302-分析化学  

张瑛  博士研究生  070302-分析化学