1. 中草药活性成分的定向发现与制备方法学研究；

2. 中草药活性成分的分子结构、构效关系、作用机制研究；

3. 基于天然产物的新药研究。

热忱欢迎对天然药物化学/药物化学、有机合成、分析化学等领域感兴趣的学生报考本课题组研究生和联合培养学生。

070302-分析化学

药物分析化学
制药工程化学

2007-09--2012-06   兰州大学   硕博连读研究生/理学博士
2003-09--2007-06   山东大学   本科生/理学学士

2007年9月-2012年6月                  博士（有机化学）

                                                       化学化工学院/功能有机分子化学国家重点实验室

                                                       兰州大学

2003年9月-2007年6月                  学士（化学）

                                                       化学与化工学院

                                                       山东大学

有机化学 博士

2018年12月 至今：研究员，中科院兰州化物所

2015年11月− 2018年12月：副研究员，****，中科院兰州化物所

2014年12月-2015年9月：Postdoctoral Research Associate ，North Carolina A&T State University/North Carolina Research Campus，USA

2013年3月-2014年11月：Postdoctoral Research Fellow，Seoul National University，Korea

2012年9月-2013年2月：Postdoctoral Researcher，Chosun University，Korea

2014-12~2015-09,North Carolina A&T State University (USA), Postdoctoral Research Associate
2013-03~2014-11,Seoul National University（South Korea）, Postdoctoral Research Fellow
2012-09~2013-02,Chosun University（South Korea）, Postdoctoral Researcher

荣誉与奖励：

1.        2015年度甘肃省自然科学奖二等奖:重要中草药化学成分和生物活性研究(排名第二)

专利:

1.         杨军丽，师彦平，从中药千年健中制备具有抑制COX-2的mRNA表达活性倍半萜的方法，2017，申请号：201710078369.8。

2.        杨军丽，王伟峰，师彦平，一种快速、高选择性检测鸟氨酸的分析方法，2017，申请号：201710078829.7。

3.         Oh, W.K.; Yang, J.L.; Kim, E.; Lee, S.C. Composition comprising extract of Camellia japonica or oleanane triterpenes derivatives isolated therefrom for treating or preventing Corona virus related diseases. Korea government application number 10-2014-0109981. 

4.        Oh, W.K.; Yang, J.L.; Kim, E. Composition comprising ginsenosides for treating or preventing Cold, Avian influenza, or Swine influenza. Korea government application number 10-2013-0137867.

（1） 重要中草药化学成分和生物活性研究, 二等奖, 省级, 2015

[1] 杨军丽, 桑春艳. 具有抗胰腺癌活性的天然化合物及其分离方法及应用. CN: CN113999245A, 2022-02-01.
[2] 杨军丽, 高召兵, 郑月明, 孟宪华, 许海燕. 具有抗癫痫活性的化合物及其在制备抗癫痫药物中的应用. CN: CN113968837A, 2022-01-25.
[3] 杨军丽, 朱玲玲, 张瑛, 赵名. 倍半萜内酯类化合物在制备治疗肾性贫血药物中的应用. CN: CN113288893A, 2021-08-24.
[4] 杨军丽, 桑春艳, 孟宪华. 一种桉烷型倍半萜类化合物在制备抗胰腺癌药物中的应用. CN: CN113143913A, 2021-07-23.
[5] 杨军丽, 孟宪华, 王铖博. 一种绞股蓝活性成分达玛烷型三萜皂苷及其分离和应用. CN: CN113135978A, 2021-07-20.
[6] 杨军丽, 桑春艳, 孟宪华. 一种愈创木烷型倍半萜类化合物在制备治疗胰腺癌药物中的应用. CN: CN113082019A, 2021-07-09.
[7] 杨军丽, 王伟峰, 张瑛. 毛细管电泳酶抑制剂精准筛选中草药活性分子的方法. CN: CN112114022A, 2020-12-22.
[8] 强音, 杨军丽. 花椒叶总黄酮提取物在抗缺氧中的应用. CN: CN110327395A, 2019-10-15.
[9] 杨军丽, 孟宪华, 王伟峰. 一种具有抗高原缺氧功能的中药组合物. CN: CN110251550A, 2019-09-20.
[10] 杨军丽, 王君, 孟宪华, 师彦平. 一种绞股蓝中具有抗阿尔茨海默病的达玛烷型三萜皂苷. CN: CN108774282A, 2018-11-09.
[11] 杨军丽, 孟宪华, 师彦平. 一种枸杞中的酰胺类化合物及酰胺类化合物组分及其制备方法. CN: CN108484428A, 2018-09-04.
[12] 杨军丽, 孟宪华, 师彦平. 一种枸杞中具有的抗阿尔茨海默病的酰胺类化合物及酰胺类化合物组分. CN: CN108299227A, 2018-07-20.
[13] 杨军丽, 孟宪华, 师彦平. 具有SIRT 1抑制活性的糖苷类化合物及其制备方法. CN: CN107936070A, 2018-04-20.
[14] 杨军丽, 孟宪华, 师彦平. 一种利用花椒根枝提取物制备的足浴粉及其制备方法. CN: CN107233421A, 2017-10-10.
[15] 杨军丽, 师彦平. 用于抑制COX‑2的mRNA表达的倍半萜类化合物及其提取方法. CN: CN106905341A, 2017-06-30.
[16] 杨军丽, 王伟峰, 师彦平. 一种检测鸟氨酸的比色分析方法. CN: CN106680270A, 2017-05-17.
[17] 师彦平, 杨军丽. 从欧亚旋覆花中提取活性倍半萜内酯的方法. CN: CN103864736A, 2014-06-18.

1.        Xian-Hua Meng, Kai Wang, Tian Chai, Zhi-Ying Guo, Ming Zhao, Jun-Li Yang*. Ingenane and jatrophane diterpenoids from Euphorbia kansui and their antiproliferative effects, Phytochemistry, 2020, 172, 112257.

2.        Wei-Feng Wang, Jun-Li Yang*. Advances in Screening Enzyme Inhibitors by Capillary Electrophoresis. Electrophoresis, 2019, 40(16-17), 2075–2083.

3.        Yu-Zhu Ding, Wei-Feng Wang, Tian Chai, Yin Qiang, Yan-Ping Shi, Jun-Li Yang^*. Ratiometric Target-Triggered Fluorescence Silicon Nanoparticles Probe for Quantitative Visulization of Tyrosinase Activity. Talanta, 2019, 197, 113-121.

4.        Wei-Feng Wang, Jun-Li Yang*, Yan-Ping Shi. Quality Evaluation of Six Bioactive Constituents in Goji Berry based on Capillary Electrophoresis Field Amplified Sample Stacking. Electrophoresis, 2018, 39(16), 2117-2124.

5.        Wei-Feng Wang, Yin Qiang, Xian-Hua Meng, Jun-Li Yang*, Yan-Ping Shi. Ultrasensitive Colorimetric Assay Melamine based on in situ Reduction to Formation of CQDs-Silver Nanocomposite. Sensors and Actuators B: Chemical, 2018, 260, 808-815.

6.        Jun Wang, Jun-Li Yang,* Pan-Pan Zhou, Xian-Hua Meng, Yan-Ping Shi. Further New Gypenosides from Jiaogulan (Gynostemma pentaphyllum). Journal of Agricultural and Food Chemistry, 2017, 65(29), 5926–5934.

7.        Yin Qiang, Wei-Feng Wang, Basanta Dhodary, Jun-Li Yang*. Zeolitic Imidazolate Framework 8 (Zif-8) Reinforced Macroporous Resin D101 for Selective Solid-Phase Extraction of 1-Naphthol and 2-Naphthol from Phenol Compounds. Electrophoresis, 2017, 38(13-14), 1685–1692.

8.        Jun Wang, Ming Zhao, Xiang Cheng, Ying Han, Tong Zhao, Ming Fan, Lingling Zhu,* Jun-Li Yang,* Dammarane-Type Saponins from Gynostemma pentaphyllum prevent hypoxia-induced neural injury through activation of ERK, Akt and CREB pathways, Journal of Agricultural and Food Chemistry, 2020, 68, 1, 193-205.

9.        Jun Wang, Thi Kim Quy Ha, Yan-Ping Shi, Won Keun Oh*, Jun-Li Yang*, Hypoglycemic Triterpenes from Gynostemma pentaphyllum. Phytochemistry, 2018, 155, 171-181.

10.    Xuan Qi, Wei-Feng Wang, Jun Wang, Jun-Li Yang *, Yan-Ping Shi *. Highly Selective Colorimetric Detection of Putrescine in Fish Products Using O-Phthalaldehyde Derivatization Reaction. Food Chemistry, 2018, 259, 245-250.

11.    Xian-Fei Zhang, Juan Chen, Jun-Li Yang*, Yan-Ping Shi*. UPLC-MS/MS Analysis for Antioxidant Components of Lycii Fructus based on Spectrum-effect Relationship. Talanta, 2018, 180, 389-395.

12.    Lei-Lei Liu, Thi Kim Quy Ha, Wei Ha, Won Keun Oh, Jun-Li Yang*, Yan-Ping Shi*. Sesquiterpenoids with Various Carbocyclic Skeletons from the Flowers of Chrysanthemum indicum. Journal of Natural Products, 2017, 80 (2), 298–307.

13.    Junli Yang, Pei Wang, Wenbin Wu, Yantao Zhao, Emmanuel Idehen, Shengmin Sang*. Steroidal Saponins in Oat Bran. Journal of Agricultural and Food Chemistry, 2016, 64(7), 1549-1556.

14.    Jun-Li Yang, Thi Kim Quy Ha, Basanta Dhodary, Kuk-Hwa Kim, Junsoo Park, Chul-Ho Lee, Young-Choong Kim, Won Keun Oh*. Dammarane Triterpenes as Potential SIRT1 Activators from the Leaves of Panax Ginseng. Journal of Natural Products, 2014, 77(7), 1615-1623.

15.    Jun-Li Yang, Yan-Ping Shi*. Cycloartane-type Triterpenoids and Sesquiterpenoids from the Resinous Eudates of Commiphora opobalsamum. Phytochemistry, 2012, 76, 124-132.

16.    Jun-Li Yang, Thi Kim Quy Ha, Basanta Dhodary, Euisun Pyo, Ngoc Hieu Nguyen, Hyomoon Cho, Eunhee Kim, Won Keun Oh*. Oleanane Triterpenes from the Flowers of Camellia japonica Inhibit Porcine Epidemic Diarrhea Virus (PEDV) Replication. Journal of Medicinal Chemistry, 2015, 58(3), 1268-1280.

[1] 杨军丽, 李沛霖, 翟小雪, 王君, 朱祥, 赵林, 尤霜, 桑春艳. Two Ferulic Acid Derivatives Inhibit Neuroinflammatory Response in Human HMC3 Microglial Cells via NF-κB Signaling Pathway. MOLECULES[J]. 2023, 28(28): 2080-, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004133/.
[2] Zhang, Ying, Nsanzamahoro, Stanislas, Wang, ChengBo, Wang, WeiFeng, Yang, JunLi. Screening of prolyl hydroxylase 2 inhibitors based on quantitative strategy of peptides. JOURNAL OF CHROMATOGRAPHY A[J]. 2022, 1679: http://dx.doi.org/10.1016/j.chroma.2022.463411.
[3] Ma, LiMei, Wang, Kai, Meng, XianHua, Zheng, YiDan, Wang, ChengBo, Chai, Tian, Naghavi, Mohammad Reza, Sang, ChunYan, Yang, JunLi. Terpenoids from Nardostachys jatamansi and their cytotoxic activity against human pancreatic cancer cell lines. PHYTOCHEMISTRY[J]. 2022, 200: http://dx.doi.org/10.1016/j.phytochem.2022.113228.
[4] Zhang, Ying, Zhao, Ming, Wang, ChengBo, Wang, Yu, Nsanzamahoro, Stanislas, Zhu, LingLing, Wang, WeiFeng, Yang, JunLi. Screening prolyl hydroxylase domain 2 inhibitory activity of traditional Chinese medicine by CZE-UV. ELECTROPHORESIS[J]. 2022, 43(15): 1601-1610, https://www.doi.org/10.1002/elps.202200028.
[5] Jiaotai Shi, Chengbo Wang, Chunyan Sang, Stanislas Nsanzamahoro, Tian Chai, Jun Wang, Aimei Yang, Junli Yang, Ramun Morknien, Dalia M Kopustinskiene. Tabersonine Inhibits the Lipopolysaccharide-Induced Neuroinflammatory Response in BV2 Microglia Cells via the NF- κ B Signaling Pathway. MOLECULES. 2022, 27(21): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654763/.
[6] 杨军丽. Gyosaponins (GPs) Alleviate Hypoxia-induced Injury in PC12 Cells and Enhance Tolerance to Anoxia in C57BL/6 Mice. Journal of Food Biochemistry[J]. 2022, [7] Geng, Yanan, Yang, Junli, Cheng, Xiang, Han, Ying, Yan, Feng, Wang, Chengbo, Jiang, Xiufang, Meng, Xianhua, Fan, Ming, Zhao, Ming, Zhu, Lingling. A bioactive gypenoside (GP-14) alleviates neuroinflammation and blood brain barrier (BBB) disruption by inhibiting the NF-?B signaling pathway in a mouse high-altitude cerebral edema (HACE) model. INTERNATIONAL IMMUNOPHARMACOLOGY[J]. 2022, 107: http://dx.doi.org/10.1016/j.intimp.2022.108675.
[8] YiDan Zheng, LiMei Ma, JinJian Lu, Tian Chai, Mohammad Reza Naghavi, JunYi Ma, ChunYan Sang, JunLi Yang. Nardoguaianone L Isolated from Nardostachys jatamansi Improved the Effect of Gemcitabine Chemotherapy via Regulating AGE Signaling Pathway in SW1990 Cells. MOLECULES[J]. 2022, 27: https://doaj.org/article/e1e47be14d9b40dfaee9ec0ab31c32ae.
[9] 杨军丽. 12. Cytotoxic Dammarane Triterpenoids from the Hydrolyzate of Gynostemma pentaphyllum. Phytochemistry Letters[J]. 2021, 46(-): 136-142, [10] Zhang, Ying, Zhong, HaiYang, Nsanzamahoro, Stanislas, Yao, XiaoJun, Wang, WeiFeng, Yang, JunLi. An online target and rapid screening method for alpha-glucosidase inhibitors based on capillary electrophoresis. ELECTROPHORESIS[J]. 2021, 42(11): 1221-1228, http://dx.doi.org/10.1002/elps.202000354.
[11] Nsanzamahoro, Stanislas, Zhang, Ying, Wang, WeiFeng, Ding, YuZhu, Shi, YanPing, Yang, JunLi. Fluorescence "turn-on" of silicon-containing nanoparticles for the determination of resorcinol. MICROCHIMICA ACTA[J]. 2021, 188(2): 46-, https://www.webofscience.com/wos/woscc/full-record/WOS:000612848400001.
[12] 杨军丽. 10. α-Glucosidase-Triggered Reaction for Fluorometric and Colorimetric Assays Based on the Formation of Silicon-Containing Nanoparticles. Analytical Chemistry[J]. 2021, 93(46): 15412-15419, [13] Nsanzamahoro, Stanislas, Wang, WeiFeng, Zhang, Ying, Shi, YanPing, Yang, JunLi. Synthesis of orange-emissive silicon nanoparticles as "off-on" fluorescence probe for sensitive and selective detection of L-methionine and copper. TALANTA[J]. 2021, 231: 122369-, http://dx.doi.org/10.1016/j.talanta.2021.122369.
[14] Wang, Kai, Meng, XianHua, Chai, Tian, Wang, ChengBo, Sang, ChunYan, Wang, WeiFeng, Shang, XianYi, Yang, JunLi. Chemical constituents from the fruits of Zanthoxylum bungeanum and their chemotaxonomic significance. BIOCHEMICAL SYSTEMATICS AND ECOLOGY[J]. 2021, 99: http://dx.doi.org/10.1016/j.bse.2021.104356.
[15] Chai, Tian, Meng, XianHua, Wang, ChengBo, Wang, Kai, Ma, LiMei, Shi, YanPing, Yang, JunLi. Narjatamolide, an Unusual Homoguaiane Sesquiterpene Lactone from Nardostachys jatamansi. JOURNAL OF ORGANIC CHEMISTRY[J]. 2021, 86(16): 11006-11010, http://dx.doi.org/10.1021/acs.joc.0c02446.
[16] JunLi Yang. An on-Line Target and Rapid Screening Method for α-Glucosidase Inhibitors based on Capillary Electrophoresis. Electrophoresis. 2021, [17] Meng, XianHua, Chai, Tian, Shi, YanPing, Yang, JunLi. Bungsteroid A: One Unusual C-34 Pentacyclic Steroid Analogue from Zanthoxylum bungeanum Maxim. JOURNAL OF ORGANIC CHEMISTRY[J]. 2020, 85(16): 10806-10812, https://www.webofscience.com/wos/woscc/full-record/WOS:000563754800043.
[18] Cho, HyoMoon, Ha, ThiKimQuy, Doan, ThiPhuong, Dhodary, Basanta, An, JinPyo, Lee, BaWool, Yang, JunLi, Oh, WonKeun. Neuroprotective Effects of Triterpenoids from Camellia japonica against Amyloid beta-Induced Neuronal Damage. JOURNAL OF NATURAL PRODUCTS[J]. 2020, 83(7): 2076-2086, https://www.webofscience.com/wos/woscc/full-record/WOS:000555517000004.
[19] 张美荣, 杨军丽, 姜侃, 师彦平. 藏药镰荚棘豆中黄酮类化学成分的研究. 中药材[J]. 2020, 43(1): 71-75, http://lib.cqvip.com/Qikan/Article/Detail?id=7102874961.
[20] 孟宪华, 尚贤毅, 杨军丽. 青花椒中酚类化学成分及其抗氧化活性. 中草药[J]. 2020, 51(8): 2095-2101, http://lib.cqvip.com/Qikan/Article/Detail?id=7101767327.
[21] Wang, Jun, Zhao, Ming, Cheng, Xiang, Han, Ying, Zhao, Tong, Fan, Ming, Zhu, Lingling, Yang, JunLi. Dammarane-Type Saponins from Gynostemma pentaphyllum Prevent Hypoxia-Induced Neural Injury through Activation of ERK, Akt, and CREB Pathways. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2020, 68(1): 193-205, http://dx.doi.org/10.1021/acs.jafc.9b06659.
[22] Tao, Luyao, Bi, Xiuru, Zhang, Liping, Chen, Gexin, Zhao, Peiqing, Yang, JunLi, Meng, Xu. Na-doped OMS-2-catalzyed highly selective aerobic oxidation of ethyl lactate to ethyl pyruvate under mild conditions. APPLIED CATALYSIS A-GENERAL[J]. 2020, 605(605): http://dx.doi.org/10.1016/j.apcata.2020.117813.
[23] Li, CaiHong, Yang, JunLi. Wolfberry extracts inhibit A beta(1-42) aggregation and rescue memory loss of AD drosophila. FOOD SCIENCE AND HUMAN WELLNESS[J]. 2020, 9(1): 64-70, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000520851800009.
[24] Meng, XianHua, Wang, Kai, Chai, Tian, Guo, ZhiYing, Zhao, Ming, Yang, JunLi. Ingenane and jatrophane diterpenoids from Euphorbia kansui and their antiproliferative effects. PHYTOCHEMISTRY[J]. 2020, 172(-): http://dx.doi.org/10.1016/j.phytochem.2020.112257.
[25] CaiHong Li, JunLi Yang. Wolfberry extracts inhibit Aβ1-42 aggregation and rescue memory loss of AD drosophila. 食品科学与人类健康[J]. 2020, 9(1): 64-70, http://lib.cqvip.com/Qikan/Article/Detail?id=7103850210.
[26] Zhang, MeiRong, Jiang, Kan, Yang, JunLi, Shi, YanPing. Flavonoids as key bioactive components of Oxytropis falcata bunge, a traditional anti-inflammatory and analgesic Tibetan medicine. NATURAL PRODUCT RESEARCH[J]. 2020, 34(23): 3335-3352, https://www.webofscience.com/wos/woscc/full-record/WOS:000594432300005.
[27] Wang, Jun, Li, CaiHong, Farimani, Mahdi Moridi, Yang, JunLi. Dammarane-type saponins from Gynostemma pentaphyllum and their potential anti-AD activity. PHYTOCHEMISTRY LETTERS[J]. 2019, 31: 147-154, http://dx.doi.org/10.1016/j.phytol.2019.03.022.
[28] Yang, JunLi, Trong Tuan Dao, Tran Thi Hien, Zhao, YaMin, Shi, YanPing. Further sesquiterpenoids from the rhizomes of Homalomena occulta and their anti-inflammatory activity. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS[J]. 2019, 29(10): 1162-1167, http://dx.doi.org/10.1016/j.bmcl.2019.03.031.
[29] JunLi Yang, LeiLei Liu, YanPing Shi. Two New Eudesmane Sesquiterpenoids from the Flowers of Chrysanthemum indicum. 应用天然产物(英文)[J]. 2019, 9(2): 145-148, http://lib.cqvip.com/Qikan/Article/Detail?id=7105123614.
[30] Thi Kim Quy Ha, Ha Thanh Tung Pham, Cho, Hyo Moon, Van On Tran, Yang, JunLi, Jung, DaWoon, Williams, Darren R, Oh, Won Keun. 12,23-Dione dammarane triterpenes from Gynostemma longipes and their muscle cell proliferation activities via activation of the AMPK pathway. SCIENTIFIC REPORTS[J]. 2019, 9(1): https://doaj.org/article/4414e2b03d8e41a8a13597eb79759011.
[31] Wang, YanMing, Zhao, JianQiang, Yang, JunLi, Idong, Pema Tsering, Mei, LiJuan, Tao, YanDuo, Shi, YanPing. Antioxidant and alpha-glucosidase inhibitory ingredients identified from Jerusalem artichoke flowers. NATURAL PRODUCT RESEARCH[J]. 2019, 33(4): 584-588, [32] Ding, YuZhu, Wang, WeiFeng, Chai, Tian, Qiang, Yin, Shi, YanPing, Yang, JunLi. Ratiometric target-triggered fluorescent silicon nanoparticles probe for quantitative visualization of tyrosinase activity. TALANTA[J]. 2019, 197: 113-121, http://210.77.64.217/handle/362003/24922.
[33] Wang, WeiFeng, Yang, JunLi. Advances in screening enzyme inhibitors by capillary electrophoresis. ELECTROPHORESISnull. 2019, 40(16-17): 2075-2083, https://www.webofscience.com/wos/woscc/full-record/WOS:000478750500007.
[34] Li, CaiHong, Meng, XianHua, Huong, Dang Lan, Oh, Won Keun, Wang, WeiFeng, Yang, JunLi. Quantitative visualization and detection of acetylcholinesterase activity and its inhibitor based on the oxidation character of ultrathin MnO2 nanosheets. ANALYTICAL METHODS[J]. 2019, 11(38): 4931-4938, [35] JunLi Yang. Ratiometric Target-Triggered Fluorescence Silicon Nanoparticles Probe for Quantitative Visulization of Tyrosinase Activity. Talanta. 2019, [36] 张弦飞, 杨军丽, 陈娟, 师彦平. 超高效合相色谱-串联质谱法快速测定枸杞中甜菜碱含量. 色谱[J]. 2018, 36(5): 417-424, http://lib.cqvip.com/Qikan/Article/Detail?id=675273824.
[37] Zhang, XianFei, Chen, Juan, Yang, JunLi, Shi, YanPing. UPLC-MS/MS analysis for antioxidant components of Lycii Fructus based on spectrum-effect relationship. TALANTA[J]. 2018, 180: 389-395, http://dx.doi.org/10.1016/j.talanta.2017.12.078.
[38] Wang, WeiFeng, Qiang, Yin, Meng, XianHua, Yang, JunLi, Shi, YanPing. Ultrasensitive colorimetric assay melamine based on in situ reduction to formation of CQDs-silver nanocomposite. SENSORS AND ACTUATORS B-CHEMICAL[J]. 2018, 260: 808-815, http://dx.doi.org/10.1016/j.snb.2018.01.108.
[39] 王君, 孟宪华, 王伟峰, 赵晓博, 李彩虹, 杨军丽, 师彦平. 抗AD活性天然化合物的结构与功能. 中国科学:化学[J]. 2018, 48(12): 1452-1465, http://lib.cqvip.com/Qikan/Article/Detail?id=6100232596.
[40] Qi, Xuan, Wang, WeiFeng, Wang, Jun, Yang, JunLi, Shi, YanPing. Highly selective colorimetric detection of putrescine in fish products using o-phthalaldehyde derivatization reaction. FOOD CHEMISTRY[J]. 2018, 259: 245-250, http://dx.doi.org/10.1016/j.foodchem.2018.03.131.
[41] Wang, WeiFeng, Qiang, Yin, Meng, XianHua, Yang, JunLi, Shi, YanPing. Ultrasensitive colorimetric assay melamine based on in situ reduction to formation of CQDs-silver nanocomposite. SENSORS AND ACTUATORS B-CHEMICAL[J]. 2018, 260: 808-815, http://dx.doi.org/10.1016/j.snb.2018.01.108.
[42] Wang, WeiFeng, Yang, JunLi, Shi, YanPing. Quality evaluation of six bioactive constituents in goji berry based on capillary electrophoresis field amplified sample stacking. ELECTROPHORESIS[J]. 2018, 39(16): 2117-2124, http://210.77.64.217/handle/362003/24657.
[43] Wang, Jun, Ha, Thi Kim Quy, Shi, YanPing, Oh, Won Keun, Yang, JunLi. Hypoglycemic triterpenes from Gynostemma pentaphyllum. PHYTOCHEMISTRY[J]. 2018, 155(155): 171-181, http://dx.doi.org/10.1016/j.phytochem.2018.08.008.
[44] Zhang Xianfei, Yang Junli, Chen Juan, Shi Yanping. 超高效合相色谱-串联质谱法快速测定枸杞中甜菜碱含量. 色谱[J]. 2018, 36(5): 417-424, http://lib.cqvip.com/Qikan/Article/Detail?id=675273824.
[45] Wang, Jun, Yang, JunLi, Zhou, PanPan, Meng, XianHua, Shi, YanPing. Further New Gypenosides from Jiaogulan (Gynostemma pentaphyllum). JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2017, 65(29): 5926-5934, http://ir.licp.ac.cn/handle/362003/22440.
[46] Kim Ji Won, Ha ThiKimQuy, Cho Hyomoon, Kim Eunhee, Shim Sang Hee, Yang JunLi, Oh Won Keun. Antiviral escin derivatives from the seeds of Aesculus turbinata Blume (Japanese horse chestnut). BIOORGANIC & MEDICINAL CHEMISTRY LETTERS[J]. 2017, [47] Wang, YanMing, Zhao, JianQiang, Yang, JunLi, Tao, YanDuo, Mei, LiJuan, Shi, YanPing. Chemical constituents from Ligularia purdomii (Turrill) Chittenden. BIOCHEMICAL SYSTEMATICS AND ECOLOGY[J]. 2017, 72: 8-11, http://dx.doi.org/10.1016/j.bse.2017.03.007.
[48] Jiang, HaiLong, Yang, JunLi, Shi, YanPing. Optimization of ultrasonic cell grinder extraction of anthocyanins from blueberry using response surface methodology. ULTRASONICS SONOCHEMISTRY[J]. 2017, 34: 325-331, http://dx.doi.org/10.1016/j.ultsonch.2016.06.003.
[49] Kim, Ji Won, Ha, ThiKimQuy, Cho, Hyomoon, Kim, Eunhee, Shim, Sang Hee, Yang, JunLi, Oh, Won Keun. Antiviral escin derivatives from the seeds of Aesculus turbinata Blume (Japanese horse chestnut). BIOORGANIC & MEDICINAL CHEMISTRY LETTERS[J]. 2017, 27(13): 3019-3025, http://dx.doi.org/10.1016/j.bmcl.2017.05.022.
[50] Wang, Pei, Yang, Junli, Yerke, Aaron, Sang, Shengmin. Avenacosides: Metabolism, and potential use as exposure biomarkers of oat intake. MOLECULAR NUTRITION & FOOD RESEARCH[J]. 2017, 61(7): https://www.webofscience.com/wos/woscc/full-record/WOS:000404730400013.
[51] Wang Jun, Yang JunLi, Zhou PanPan, Meng XianHua, Shi YanPing. Further New Gypenosides from Jiaogulan ( Gynostemma pentaphyllum ). JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2017, [52] Wang, YanMing, Zhao, JianQiang, Yang, JunLi, Tao, YanDuo, Mei, LiJuan, Shi, YanPing. Separation of antioxidant and -glucosidase inhibitory flavonoids from the aerial parts of Asterothamnus centrali-asiaticus. NATURAL PRODUCT RESEARCH[J]. 2017, 31(12): 1365-1369, http://210.75.249.4/handle/363003/6830.
[53] Yang, Jun Li, Thi Kim Quy Ha, Lee, Ba Wool, Kim, Jinwoong, Oh, Won Keun. PTP1B inhibitors from the seeds of Iris sanguinea and their insulin mimetic activities via AMPK and ACC phosphorylation. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS[J]. 2017, 27(22): 5076-5081, http://dx.doi.org/10.1016/j.bmcl.2017.09.031.
[54] Nguyen PhiHung, Choi Hong Seok, Ha Thi Kim Quy, Seo Ji Yeon, Yang JunLi, Jung DaWoon, Williams Darren R, Oh WonKeun. Anthraquinones from Morinda longissima and their insulin mimetic activities via AMP-activated protein kinase (AMPK) activation. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS[J]. 2017, [55] Qiang, Yin, Wang, WeiFeng, Dhodary, Basanta, Yang, JunLi. Zeolitic imidazolate framework 8 (ZIF-8) reinforced macroporous resin D101 for selective solid-phase extraction of 1-naphthol and 2-naphthol from phenol compounds. ELECTROPHORESIS[J]. 2017, 38(13-14): 1685-1692, https://www.webofscience.com/wos/woscc/full-record/WOS:000406724100004.
[56] Zhao, XiaoBo, Ha, Wei, Jiang, Kan, Chen, Juan, Yang, JunLi, Shi, YanPing. Efficient synthesis of camptothecin propargylamine derivatives in water catalyzed by macroporous adsorption resin-supported gold nanoparticles. GREEN CHEMISTRY[J]. 2017, 19(5): 1399-1406, http://www.irgrid.ac.cn/handle/1471x/1181113.
[57] Liu, LeiLei, Ha, Thi Kim Quy, Ha, Wei, Oh, Won Keun, Yang, JunLi, Shi, YanPing. Sesquiterpenoids with Various Carbocyclic Skeletons from the Flowers of Chrysanthemum indicum. JOURNAL OF NATURAL PRODUCTS[J]. 2017, 80(2): 298-307, http://www.irgrid.ac.cn/handle/1471x/1181105.
[58] Liu, DongMei, Yang, JunLi, Ha, Wei, Chen, Juan, Shi, YanPing. Kinetics and inhibition study of tyrosinase by pressure mediated microanalysis. ANALYTICAL BIOCHEMISTRY[J]. 2017, 525: 54-59, http://dx.doi.org/10.1016/j.ab.2017.02.020.
[59] Zhang, XianFei, Yang, JunLi, Chen, Juan, Shi, YanPing. Optimization of a Decoction Process for an Herbal Formula Using a Response Surface Methodology. JOURNAL OF AOAC INTERNATIONAL[J]. 2017, 100(6): 1776-1784, http://ir.licp.ac.cn/handle/362003/22857.
[60] Ji Won Kim, ThiKimQuy Ha, Hyomoon Cho, Eunhee Kim, Sang Hee Shim, 杨军丽, Won Keun Oh. Antiviral escin derivatives from the seeds of Aesculus turbinata Blume (Japanese horse chestnut). BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS[J]. 2017, 27(13): 3019-3025, http://dx.doi.org/10.1016/j.bmcl.2017.05.022.
[61] Yang, Jun Li, Thi Kim Quy Ha, Dhodary, Basanta, Seo, Ji Yeon, Kim, Hyunju, Park, Junsoo, Oh, Won Keun. 3,4-seco-28-Nor-oleanane triterpenes from Camellia japonica protect from neurotoxicity in a rotenone model of Parkinson's disease. TETRAHEDRON[J]. 2016, 72(23): 3240-3249, http://dx.doi.org/10.1016/j.tet.2016.04.045.
[62] Wang, YanMing, Zhao, JianQiang, Zhou, ShuangYan, Yang, JunLi, Yao, XiaoJun, Tao, YanDuo, Mei, LiJuan, Shi, YanPing. New sesquiterpenes and benzofuran derivatives from the aerial parts of Asterothamnus centrali-asiaticus. TETRAHEDRON[J]. 2016, 72(32): 4910-4917, http://dx.doi.org/10.1016/j.tet.2016.06.061.
[63] Yang, ChunYan, Ha, Wei, Lin, Yong, Jiang, Kan, Yang, JunLi, Shi, YanPing. Polyphenols Isolated from Xanthoceras sorbifolia Husks and Their Anti-Tumor and Radical-Scavenging Activities. MOLECULES[J]. 2016, 21(12): http://www.irgrid.ac.cn/handle/1471x/1143176.
[64] Wang, YanMing, Zhao, JianQiang, Yang, JunLi, Tao, YanDuo, Mei, LiJuan, Shi, YanPing. Isolation and Identification of Saponins from the Natural Pasturage Asterothamnus centrali-asiaticus Employing Preparative Two-Dimensional Reversed-Phase Liquid Chromatography/Hydrophilic Interaction Chromatography. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2016, 64(24): 4950-4957, http://210.75.249.4/handle/363003/6481.
[65] Yang, Junli, Wang, Pei, Wu, Wenbin, Zhao, Yantao, Idehen, Emmanuel, Sang, Shengmin. Steroidal Saponins in Oat Bran. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2016, 64(7): 1549-1556, http://dx.doi.org/10.1021/acs.jafc.5b06071.
[66] Jiang, HaiLong, Ha, Wei, Yang, JunLi, Shi, YanPing. New sesquiterpene polyol esters from the root bark of Pseudolarix kaempferi. PHYTOCHEMISTRY LETTERS[J]. 2016, 17: 1-5, http://dx.doi.org/10.1016/j.phytol.2016.06.004.
[67] JunLi Yang. New sesquiterpene polyol esters from the root barks of Pseudolarix kaempferi. Phytochemistry Letters. 2016, [68] Yang, JunLi, ThiKimQuy Ha, Dhodary, Basanta, Pyo, Euisun, Ngoc Hieu Nguyen, Cho, Hyomoon, Kim, Eunhee, Oh, Won Keun. Oleanane Triterpenes from the Flowers of Camellia japonica Inhibit Porcine Epidemic Diarrhea Virus (PEDV) Replication. JOURNALOFMEDICINALCHEMISTRY[J]. 2015, 58(3): 1268-1280, https://www.webofscience.com/wos/woscc/full-record/WOS:000349573800019.
[69] Yang, JunLi, Dhodary, Basanta, Ha, Thi Kim Quy, Kim, Jinwoong, Kim, Eunhee, Oh, Won Keun. Three new coumarins from Saposhnikovia divaricata and their porcine epidemic diarrhea virus (PEDV) inhibitory activity. TETRAHEDRON[J]. 2015, 71(28): 4651-4658, http://dx.doi.org/10.1016/j.tet.2015.04.092.
[70] Yang, JunLi, Ha, ThiKimQuy, Dhodary, Basanta, Kim, KukHwa, Park, Junsoo, Lee, ChulHo, Kim, YoungChoong, Oh, WonKeun. Dammarane Triterpenes as Potential SIRT1 Activators from the Leaves of Panax ginseng. JOURNAL OF NATURAL PRODUCTS[J]. 2014, 77(7): 1615-1623, https://www.webofscience.com/wos/woscc/full-record/WOS:000339604300010.
[71] Yang, JunLi, Shi, YanPing. Cycloartane-type triterpenoids and sesquiterpenoids from the resinous exudates of Commiphora opobalsamum. PHYTOCHEMISTRY[J]. 2012, 76: 124-132, http://dx.doi.org/10.1016/j.phytochem.2012.01.004.
[72] Liu Leilei, Wang Rui, Yang Junli, Shi Yanping. Five New Sesquiterpenoids from Chrysanthemum indicum. 中国化学：英文版[J]. 2012, 30(6): 1255-1260, http://lib.cqvip.com/Qikan/Article/Detail?id=42601396.
[73] Jiang, HaiLong, Luo, XiaoHong, Wang, XiaoZheng, Yang, JunLi, Yao, XiaoJun, Crews, Phillip, Valeriote, Frederick A, Wu, QuanXiang. New isocoumarins and alkaloid from Chinese insect medicine, Eupolyphaga sinensis Walker. FITOTERAPIA[J]. 2012, 83(7): 1275-1280, http://dx.doi.org/10.1016/j.fitote.2012.06.005.
[74] Liu Leilei, Wang Rui, Yang Junli, Shi Yanping. Five New Sesquiterpenoids from Chrysanthemum indicum. CHINESE JOURNAL OF CHEMISTRY[J]. 2012, 30(6): 1255-1260, http://lib.cqvip.com/Qikan/Article/Detail?id=42601396.
[75] Yang, JunLi, Shi, YanPing. Structurally Diverse Terpenoids from the Rhizomes of Cyperus rotundus L.. PLANTA MEDICA[J]. 2012, 78(1): 59-64, http://www.irgrid.ac.cn/handle/1471x/1030184.
[76] Liu, LeiLei, Yang, JunLi, Shi, YanPing. Sesquiterpenoids and other constituents from the flower buds of Tussilago farfara. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH[J]. 2011, 13(10): 920-929, http://www.irgrid.ac.cn/handle/1471x/521118.
[77] Yang, JunLi, Liu, LeiLei, Shi, YanPing. Limonoids and Quinoline Alkaloids from Dictamnus dasycarpus. PLANTA MEDICA[J]. 2011, 77(3): 271-276, http://www.irgrid.ac.cn/handle/1471x/521115.
[78] Gong, HaiQun, Wu, QuanXiang, Liu, LeiLei, Yang, JunLi, Wang, Rui, Shi, YanPing. Sesquiterpenoids from the Aerial Parts of Inula japonica. HELVETICA CHIMICA ACTA[J]. 2011, 94(7): 1269-1276, http://dx.doi.org/10.1002/hlca.201000417.
[79] Yang, JunLi, Wang, Rui, Liu, LeiLei, Shi, YanPing. Sesquiterpenoids from Inula britannica. PLANTA MEDICA[J]. 2011, 77(4): 362-367, http://www.irgrid.ac.cn/handle/1471x/521116.
[80] 龚海群, 武全香, 刘磊磊, 杨军丽, 王瑞, 师彦平. Sesquiterpenoids from the aerial parts of Inula japonica. HEIVETICA CHIMICA ACTA[J]. 2011, 94: 1269-1276, http://www.irgrid.ac.cn/handle/1471x/521117.
[81] Liu, LeiLei, Wang, Rui, Yang, JunLi, Shi, YanPing. Diversity of Sesquiterpenoids from Carpesium cernuum. HELVETICA CHIMICA ACTA[J]. 2010, 93(3): 595-601, http://www.irgrid.ac.cn/handle/1471x/516053.
[82] Yang, JunLi, Liu, LeiLei, Wang, BinGui, Shi, YanPing. Secondary metabolites from Grateloupia turuturu and their chemotaxonomic significance. BIOCHEMICAL SYSTEMATICS AND ECOLOGY[J]. 2010, 38(4): 850-852, http://dx.doi.org/10.1016/j.bse.2010.07.015.
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1.     国家重点研发计划 “基于中伊传统草药的抗AD药物候选化合物研究”（主持，2018YFE0182500）

2.    中国科学院“率先行动****”人才项目：“植物源活性天然产物的快速发现与应用”（主持）

3.    国家自然科学基金面上项目“基于超滤质谱和超低温探头NMR技术的三种花椒属植物中SIRT1抑制剂的快速发现及其抗肿瘤活性研究”（ 主持，81673325）

（ 1 ） 中国科学院率先行动“****”项目, 主持, 部委级, 2015-11--2018-12
（ 2 ） 基于超滤质谱和超低温探头NMR技术的三种花椒属植物中SIRT1抑制剂的快速发现及其抗肿瘤活性研究, 主持, 国家级, 2017-01--2020-12
（ 3 ） "一带一路”民族药研发与产业化合作, 参与, 部委级, 2016-01--2020-12
（ 4 ） 中韩药用植物抗衰老活性分子研究, 主持, 国家级, 2017-07--2019-06
（ 5 ） 甘肃花椒活性成分发现与宏量制备关键技术一带一路国际科技合作研究, 参与, 省级, 2018-07--2020-06
（ 6 ） 中科院2019年度特别交流计划项目“中亚植物药研究（A类）”, 主持, 部委级, 2019-01--2020-12
（ 7 ） 基于西北特色植物资源的改善认知损伤的药物筛选与评价, 主持, 研究所（学校）, 2019-01--2021-12

（1）Bioactive Natural Compounds from Plants in Northwestern China   天然药物活性成分结构与功能国际研讨会   2019-06-06
（2）中药萜类化学成分发现与活性评价   中国化学会第十届全国有机化学学术会议   杨军丽   2017-12-19
（3）Chemical Constitutes and Biological Activities of TCMs   第十二届天然化合物化学国际研讨会   2017-09-06
（4）Chemical Constitutes and Biological Activities on TCMs    第五届可食和药用植物资源及功能成分国际学术研讨会   2016-11-04
（5）Bioactive Natural Products from Medicinal Plants   天然产物分离分析新技术国际学术研讨会   2016-11-04
（6）植物源天然化合物的发现与生物活性研究   中国化学会第十一届全国天然有机化学学术会议   2016-09-25

已指导学生

祁轩  硕士研究生  070303-有机化学  

王君  博士研究生  070302-分析化学  

现指导学生

李彩虹  硕士研究生  070302-分析化学  

马丽梅  硕士研究生  070302-分析化学  

陶璐瑶  硕士研究生  085235-制药工程  

丁玉竹  博士研究生  070302-分析化学  

马丽  硕士研究生  070302-分析化学  

王凯  博士研究生  070302-分析化学  

张瑛  博士研究生  070302-分析化学