
杨军丽 男 研究员 博导 中国科学院兰州化学物理研究所
电子邮件: yangjl@licp.cas.cn
通信地址: 兰州市天水中路18号
邮政编码: 730000
研究领域
1. 中草药活性成分的定向发现与制备方法学研究;
2. 中草药活性成分的分子结构、构效关系、作用机制研究;
3. 基于天然产物的新药研究。
招生信息
招生专业
招生方向
制药工程化学
教育背景
2003-09--2007-06 山东大学 本科生/理学学士
学历
2007年9月-2012年6月 博士(有机化学)
化学化工学院/功能有机分子化学国家重点实验室
兰州大学
2003年9月-2007年6月 学士(化学)
化学与化工学院
山东大学
学位
工作经历
2018年12月 至今:研究员,中科院兰州化物所
2015年11月− 2018年12月:副研究员,****,中科院兰州化物所
2014年12月-2015年9月:Postdoctoral Research Associate ,North Carolina A&T State University/North Carolina Research Campus,USA
2013年3月-2014年11月:Postdoctoral Research Fellow,Seoul National University,Korea
2012年9月-2013年2月:Postdoctoral Researcher,Chosun University,Korea
工作简历
2013-03~2014-11,Seoul National University(South Korea), Postdoctoral Research Fellow
2012-09~2013-02,Chosun University(South Korea), Postdoctoral Researcher
专利与奖励
荣誉与奖励:
1. 2015年度甘肃省自然科学奖二等奖:重要中草药化学成分和生物活性研究(排名第二)
专利:
1. 杨军丽,师彦平,从中药千年健中制备具有抑制COX-2的mRNA表达活性倍半萜的方法,2017,申请号:201710078369.8。
2. 杨军丽,王伟峰,师彦平,一种快速、高选择性检测鸟氨酸的分析方法,2017,申请号:201710078829.7。
3. Oh, W.K.; Yang, J.L.; Kim, E.; Lee, S.C. Composition comprising extract of Camellia japonica or oleanane triterpenes derivatives isolated therefrom for treating or preventing Corona virus related diseases. Korea government application number 10-2014-0109981.
4. Oh, W.K.; Yang, J.L.; Kim, E. Composition comprising ginsenosides for treating or preventing Cold, Avian influenza, or Swine influenza. Korea government application number 10-2013-0137867.
奖励信息
专利成果
[2] 杨军丽, 高召兵, 郑月明, 孟宪华, 许海燕. 具有抗癫痫活性的化合物及其在制备抗癫痫药物中的应用. CN: CN113968837A, 2022-01-25.
[3] 杨军丽, 朱玲玲, 张瑛, 赵名. 倍半萜内酯类化合物在制备治疗肾性贫血药物中的应用. CN: CN113288893A, 2021-08-24.
[4] 杨军丽, 桑春艳, 孟宪华. 一种桉烷型倍半萜类化合物在制备抗胰腺癌药物中的应用. CN: CN113143913A, 2021-07-23.
[5] 杨军丽, 孟宪华, 王铖博. 一种绞股蓝活性成分达玛烷型三萜皂苷及其分离和应用. CN: CN113135978A, 2021-07-20.
[6] 杨军丽, 桑春艳, 孟宪华. 一种愈创木烷型倍半萜类化合物在制备治疗胰腺癌药物中的应用. CN: CN113082019A, 2021-07-09.
[7] 杨军丽, 王伟峰, 张瑛. 毛细管电泳酶抑制剂精准筛选中草药活性分子的方法. CN: CN112114022A, 2020-12-22.
[8] 强音, 杨军丽. 花椒叶总黄酮提取物在抗缺氧中的应用. CN: CN110327395A, 2019-10-15.
[9] 杨军丽, 孟宪华, 王伟峰. 一种具有抗高原缺氧功能的中药组合物. CN: CN110251550A, 2019-09-20.
[10] 杨军丽, 王君, 孟宪华, 师彦平. 一种绞股蓝中具有抗阿尔茨海默病的达玛烷型三萜皂苷. CN: CN108774282A, 2018-11-09.
[11] 杨军丽, 孟宪华, 师彦平. 一种枸杞中的酰胺类化合物及酰胺类化合物组分及其制备方法. CN: CN108484428A, 2018-09-04.
[12] 杨军丽, 孟宪华, 师彦平. 一种枸杞中具有的抗阿尔茨海默病的酰胺类化合物及酰胺类化合物组分. CN: CN108299227A, 2018-07-20.
[13] 杨军丽, 孟宪华, 师彦平. 具有SIRT 1抑制活性的糖苷类化合物及其制备方法. CN: CN107936070A, 2018-04-20.
[14] 杨军丽, 孟宪华, 师彦平. 一种利用花椒根枝提取物制备的足浴粉及其制备方法. CN: CN107233421A, 2017-10-10.
[15] 杨军丽, 师彦平. 用于抑制COX‑2的mRNA表达的倍半萜类化合物及其提取方法. CN: CN106905341A, 2017-06-30.
[16] 杨军丽, 王伟峰, 师彦平. 一种检测鸟氨酸的比色分析方法. CN: CN106680270A, 2017-05-17.
[17] 师彦平, 杨军丽. 从欧亚旋覆花中提取活性倍半萜内酯的方法. CN: CN103864736A, 2014-06-18.
出版信息
1. Xian-Hua Meng, Kai Wang, Tian Chai, Zhi-Ying Guo, Ming Zhao, Jun-Li Yang*. Ingenane and jatrophane diterpenoids from Euphorbia kansui and their antiproliferative effects, Phytochemistry, 2020, 172, 112257.
2. Wei-Feng Wang, Jun-Li Yang*. Advances in Screening Enzyme Inhibitors by Capillary Electrophoresis. Electrophoresis, 2019, 40(16-17), 2075–2083.
3. Yu-Zhu Ding, Wei-Feng Wang, Tian Chai, Yin Qiang, Yan-Ping Shi, Jun-Li Yang*. Ratiometric Target-Triggered Fluorescence Silicon Nanoparticles Probe for Quantitative Visulization of Tyrosinase Activity. Talanta, 2019, 197, 113-121.
4. Wei-Feng Wang, Jun-Li Yang*, Yan-Ping Shi. Quality Evaluation of Six Bioactive Constituents in Goji Berry based on Capillary Electrophoresis Field Amplified Sample Stacking. Electrophoresis, 2018, 39(16), 2117-2124.
5. Wei-Feng Wang, Yin Qiang, Xian-Hua Meng, Jun-Li Yang*, Yan-Ping Shi. Ultrasensitive Colorimetric Assay Melamine based on in situ Reduction to Formation of CQDs-Silver Nanocomposite. Sensors and Actuators B: Chemical, 2018, 260, 808-815.
6. Jun Wang, Jun-Li Yang,* Pan-Pan Zhou, Xian-Hua Meng, Yan-Ping Shi. Further New Gypenosides from Jiaogulan (Gynostemma pentaphyllum). Journal of Agricultural and Food Chemistry, 2017, 65(29), 5926–5934.
7. Yin Qiang, Wei-Feng Wang, Basanta Dhodary, Jun-Li Yang*. Zeolitic Imidazolate Framework 8 (Zif-8) Reinforced Macroporous Resin D101 for Selective Solid-Phase Extraction of 1-Naphthol and 2-Naphthol from Phenol Compounds. Electrophoresis, 2017, 38(13-14), 1685–1692.
8. Jun Wang, Ming Zhao, Xiang Cheng, Ying Han, Tong Zhao, Ming Fan, Lingling Zhu,* Jun-Li Yang,* Dammarane-Type Saponins from Gynostemma pentaphyllum prevent hypoxia-induced neural injury through activation of ERK, Akt and CREB pathways, Journal of Agricultural and Food Chemistry, 2020, 68, 1, 193-205.
9. Jun Wang, Thi Kim Quy Ha, Yan-Ping Shi, Won Keun Oh*, Jun-Li Yang*, Hypoglycemic Triterpenes from Gynostemma pentaphyllum. Phytochemistry, 2018, 155, 171-181.
10. Xuan Qi, Wei-Feng Wang, Jun Wang, Jun-Li Yang *, Yan-Ping Shi *. Highly Selective Colorimetric Detection of Putrescine in Fish Products Using O-Phthalaldehyde Derivatization Reaction. Food Chemistry, 2018, 259, 245-250.
11. Xian-Fei Zhang, Juan Chen, Jun-Li Yang*, Yan-Ping Shi*. UPLC-MS/MS Analysis for Antioxidant Components of Lycii Fructus based on Spectrum-effect Relationship. Talanta, 2018, 180, 389-395.
12. Lei-Lei Liu, Thi Kim Quy Ha, Wei Ha, Won Keun Oh, Jun-Li Yang*, Yan-Ping Shi*. Sesquiterpenoids with Various Carbocyclic Skeletons from the Flowers of Chrysanthemum indicum. Journal of Natural Products, 2017, 80 (2), 298–307.
13. Junli Yang, Pei Wang, Wenbin Wu, Yantao Zhao, Emmanuel Idehen, Shengmin Sang*. Steroidal Saponins in Oat Bran. Journal of Agricultural and Food Chemistry, 2016, 64(7), 1549-1556.
14. Jun-Li Yang, Thi Kim Quy Ha, Basanta Dhodary, Kuk-Hwa Kim, Junsoo Park, Chul-Ho Lee, Young-Choong Kim, Won Keun Oh*. Dammarane Triterpenes as Potential SIRT1 Activators from the Leaves of Panax Ginseng. Journal of Natural Products, 2014, 77(7), 1615-1623.
15. Jun-Li Yang, Yan-Ping Shi*. Cycloartane-type Triterpenoids and Sesquiterpenoids from the Resinous Eudates of Commiphora opobalsamum. Phytochemistry, 2012, 76, 124-132.
16. Jun-Li Yang, Thi Kim Quy Ha, Basanta Dhodary, Euisun Pyo, Ngoc Hieu Nguyen, Hyomoon Cho, Eunhee Kim, Won Keun Oh*. Oleanane Triterpenes from the Flowers of Camellia japonica Inhibit Porcine Epidemic Diarrhea Virus (PEDV) Replication. Journal of Medicinal Chemistry, 2015, 58(3), 1268-1280.
发表论文
[2] 杨军丽, 李沛霖, 翟小雪, 王君, 朱祥, 赵林, 尤霜, 桑春艳. Two Ferulic Acid Derivatives Inhibit Neuroinflammatory Response in Human HMC3 Microglial Cells via NF-κB Signaling Pathway. MOLECULES[J]. 2023, 第 1 作者28(28): 2080, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10004133/.
[3] Zhang, Ying, Nsanzamahoro, Stanislas, Wang, ChengBo, Wang, WeiFeng, Yang, JunLi. Screening of prolyl hydroxylase 2 inhibitors based on quantitative strategy of peptides. JOURNAL OF CHROMATOGRAPHY A[J]. 2022, 第 5 作者 通讯作者 1679: http://dx.doi.org/10.1016/j.chroma.2022.463411.
[4] Ma, LiMei, Wang, Kai, Meng, XianHua, Zheng, YiDan, Wang, ChengBo, Chai, Tian, Naghavi, Mohammad Reza, Sang, ChunYan, Yang, JunLi. Terpenoids from Nardostachys jatamansi and their cytotoxic activity against human pancreatic cancer cell lines. PHYTOCHEMISTRY[J]. 2022, 第 9 作者 通讯作者 200: http://dx.doi.org/10.1016/j.phytochem.2022.113228.
[5] Zhang, Ying, Zhao, Ming, Wang, ChengBo, Wang, Yu, Nsanzamahoro, Stanislas, Zhu, LingLing, Wang, WeiFeng, Yang, JunLi. Screening prolyl hydroxylase domain 2 inhibitory activity of traditional Chinese medicine by CZE-UV. ELECTROPHORESIS[J]. 2022, 第 8 作者 通讯作者 43(15): 1601-1610, https://www.doi.org/10.1002/elps.202200028.
[6] Jiaotai Shi, Chengbo Wang, Chunyan Sang, Stanislas Nsanzamahoro, Tian Chai, Jun Wang, Aimei Yang, Junli Yang, Ramun Morknien, Dalia M Kopustinskiene. Tabersonine Inhibits the Lipopolysaccharide-Induced Neuroinflammatory Response in BV2 Microglia Cells via the NF- κ B Signaling Pathway. MOLECULES. 2022, 第 8 作者27(21): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654763/.
[7] 杨军丽. Gyosaponins (GPs) Alleviate Hypoxia-induced Injury in PC12 Cells and Enhance Tolerance to Anoxia in C57BL/6 Mice. Journal of Food Biochemistry[J]. 2022, 第 1 作者
[8] 马丽, 王嘉霖, 柴甜, 王铖博, 孟宪华, 杨军丽. 甘遂中的新三萜及其抗氧化活性. 中草药[J]. 2022, 第 6 作者53(8): 2269-2273, http://lib.cqvip.com/Qikan/Article/Detail?id=7107162210.
[9] 马丽, 孟宪华, 杨军丽. 甘遂化学成分、药理活性和临床应用研究进展. 天然产物研究与开发[J]. 2022, 第 3 作者34(4): 699-712, http://lib.cqvip.com/Qikan/Article/Detail?id=7107082802.
[10] 刘建飞, 巩媛, 杨军丽, 邸多隆. 枸杞属植物中生物碱类成分研究进展. 科学通报[J]. 2022, 第 3 作者67(4): 332-350, http://lib.cqvip.com/Qikan/Article/Detail?id=7106752359.
[11] Geng, Yanan, Yang, Junli, Cheng, Xiang, Han, Ying, Yan, Feng, Wang, Chengbo, Jiang, Xiufang, Meng, Xianhua, Fan, Ming, Zhao, Ming, Zhu, Lingling. A bioactive gypenoside (GP-14) alleviates neuroinflammation and blood brain barrier (BBB) disruption by inhibiting the NF-?B signaling pathway in a mouse high-altitude cerebral edema (HACE) model. INTERNATIONAL IMMUNOPHARMACOLOGY[J]. 2022, 第 2 作者107: http://dx.doi.org/10.1016/j.intimp.2022.108675.
[12] YiDan Zheng, LiMei Ma, JinJian Lu, Tian Chai, Mohammad Reza Naghavi, JunYi Ma, ChunYan Sang, JunLi Yang. Nardoguaianone L Isolated from Nardostachys jatamansi Improved the Effect of Gemcitabine Chemotherapy via Regulating AGE Signaling Pathway in SW1990 Cells. MOLECULES[J]. 2022, 第 8 作者27: https://doaj.org/article/e1e47be14d9b40dfaee9ec0ab31c32ae.
[13] 杨军丽. 12. Cytotoxic Dammarane Triterpenoids from the Hydrolyzate of Gynostemma pentaphyllum. Phytochemistry Letters[J]. 2021, 第 1 作者46(-): 136-142,
[14] Zhang, Ying, Zhong, HaiYang, Nsanzamahoro, Stanislas, Yao, XiaoJun, Wang, WeiFeng, Yang, JunLi. An online target and rapid screening method for alpha-glucosidase inhibitors based on capillary electrophoresis. ELECTROPHORESIS[J]. 2021, 第 6 作者 通讯作者 42(11): 1221-1228, http://dx.doi.org/10.1002/elps.202000354.
[15] Nsanzamahoro, Stanislas, Zhang, Ying, Wang, WeiFeng, Ding, YuZhu, Shi, YanPing, Yang, JunLi. Fluorescence "turn-on" of silicon-containing nanoparticles for the determination of resorcinol. MICROCHIMICA ACTA[J]. 2021, 第 6 作者 通讯作者 188(2): 46, https://www.webofscience.com/wos/woscc/full-record/WOS:000612848400001.
[16] 杨军丽. 10. α-Glucosidase-Triggered Reaction for Fluorometric and Colorimetric Assays Based on the Formation of Silicon-Containing Nanoparticles. Analytical Chemistry[J]. 2021, 第 1 作者93(46): 15412-15419,
[17] Nsanzamahoro, Stanislas, Wang, WeiFeng, Zhang, Ying, Shi, YanPing, Yang, JunLi. Synthesis of orange-emissive silicon nanoparticles as "off-on" fluorescence probe for sensitive and selective detection of L-methionine and copper. TALANTA[J]. 2021, 第 5 作者 通讯作者 231: 122369, http://dx.doi.org/10.1016/j.talanta.2021.122369.
[18] Wang, Kai, Meng, XianHua, Chai, Tian, Wang, ChengBo, Sang, ChunYan, Wang, WeiFeng, Shang, XianYi, Yang, JunLi. Chemical constituents from the fruits of Zanthoxylum bungeanum and their chemotaxonomic significance. BIOCHEMICAL SYSTEMATICS AND ECOLOGY[J]. 2021, 第 8 作者 通讯作者 99: http://dx.doi.org/10.1016/j.bse.2021.104356.
[19] Chai, Tian, Meng, XianHua, Wang, ChengBo, Wang, Kai, Ma, LiMei, Shi, YanPing, Yang, JunLi. Narjatamolide, an Unusual Homoguaiane Sesquiterpene Lactone from Nardostachys jatamansi. JOURNAL OF ORGANIC CHEMISTRY[J]. 2021, 第 7 作者 通讯作者 86(16): 11006-11010, http://dx.doi.org/10.1021/acs.joc.0c02446.
[20] JunLi Yang. An on-Line Target and Rapid Screening Method for α-Glucosidase Inhibitors based on Capillary Electrophoresis. Electrophoresis. 2021, 第 1 作者 通讯作者
[21] 刘建飞, 巩媛, 杨军丽, 邸多隆. 枸杞属植物中生物碱类成分研究进展. 科学通报[J]. 2021, 第 3 作者67(66): 1-19, https://t.cnki.net/kcms/detail?v=3uoqIhG8C46NmWw7YpEsKHTPvOGrUOOqX1coEOzL8AFzMEF_Swq8Fs2j8d1-lfospb0XA3fnzzglHhogtDCKlE1_fg1NwFEW.
[22] 马丽梅, 杨军丽. 羌活药材的化学成分和药理活性研究进展. 中草药[J]. 2021, 第 2 作者52(19): 6111-6120, http://lib.cqvip.com/Qikan/Article/Detail?id=7106078343.
[23] Stanislas Nsanzamahoro, 师彦平, 杨军丽. -glucosidase- triggered reaction for fluorometric and colorimetric assay based on formation of silicon-containing nanoparticles. Analytical Chemistry[J]. 2021, 第 3 作者 通讯作者 93: 15412-15419,
[24] 李春丽, 孟宪华, 尚贤毅, 赵娅敏, 杨军丽. 花椒化学成分及其抗氧化活性. 中草药[J]. 2021, 第 5 作者52(10): 2869-2875, http://lib.cqvip.com/Qikan/Article/Detail?id=7104879206.
[25] Meng, XianHua, Chai, Tian, Shi, YanPing, Yang, JunLi. Bungsteroid A: One Unusual C-34 Pentacyclic Steroid Analogue from Zanthoxylum bungeanum Maxim. JOURNAL OF ORGANIC CHEMISTRY[J]. 2020, 第 4 作者 通讯作者 85(16): 10806-10812, https://www.webofscience.com/wos/woscc/full-record/WOS:000563754800043.
[26] Cho, HyoMoon, Ha, ThiKimQuy, Doan, ThiPhuong, Dhodary, Basanta, An, JinPyo, Lee, BaWool, Yang, JunLi, Oh, WonKeun. Neuroprotective Effects of Triterpenoids from Camellia japonica against Amyloid beta-Induced Neuronal Damage. JOURNAL OF NATURAL PRODUCTS[J]. 2020, 第 7 作者83(7): 2076-2086, https://www.webofscience.com/wos/woscc/full-record/WOS:000555517000004.
[27] 张美荣, 杨军丽, 姜侃, 师彦平. 藏药镰荚棘豆中黄酮类化学成分的研究. 中药材[J]. 2020, 第 2 作者43(1): 71-75, http://lib.cqvip.com/Qikan/Article/Detail?id=7102874961.
[28] 孟宪华, 尚贤毅, 杨军丽. 青花椒中酚类化学成分及其抗氧化活性. 中草药[J]. 2020, 第 3 作者51(8): 2095-2101, http://lib.cqvip.com/Qikan/Article/Detail?id=7101767327.
[29] Wang, Jun, Zhao, Ming, Cheng, Xiang, Han, Ying, Zhao, Tong, Fan, Ming, Zhu, Lingling, Yang, JunLi. Dammarane-Type Saponins from Gynostemma pentaphyllum Prevent Hypoxia-Induced Neural Injury through Activation of ERK, Akt, and CREB Pathways. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2020, 第 8 作者 通讯作者 68(1): 193-205, http://dx.doi.org/10.1021/acs.jafc.9b06659.
[30] Tao, Luyao, Bi, Xiuru, Zhang, Liping, Chen, Gexin, Zhao, Peiqing, Yang, JunLi, Meng, Xu. Na-doped OMS-2-catalzyed highly selective aerobic oxidation of ethyl lactate to ethyl pyruvate under mild conditions. APPLIED CATALYSIS A-GENERAL[J]. 2020, 第 6 作者 通讯作者 605(605): http://dx.doi.org/10.1016/j.apcata.2020.117813.
[31] Li, CaiHong, Yang, JunLi. Wolfberry extracts inhibit A beta(1-42) aggregation and rescue memory loss of AD drosophila. FOOD SCIENCE AND HUMAN WELLNESS[J]. 2020, 第 2 作者 通讯作者 9(1): 64-70, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000520851800009.
[32] Meng, XianHua, Wang, Kai, Chai, Tian, Guo, ZhiYing, Zhao, Ming, Yang, JunLi. Ingenane and jatrophane diterpenoids from Euphorbia kansui and their antiproliferative effects. PHYTOCHEMISTRY[J]. 2020, 第 6 作者 通讯作者 172(-): http://dx.doi.org/10.1016/j.phytochem.2020.112257.
[33] CaiHong Li, JunLi Yang. Wolfberry extracts inhibit Aβ1-42 aggregation and rescue memory loss of AD drosophila. 食品科学与人类健康[J]. 2020, 第 2 作者9(1): 64-70, http://lib.cqvip.com/Qikan/Article/Detail?id=7103850210.
[34] Zhang, MeiRong, Jiang, Kan, Yang, JunLi, Shi, YanPing. Flavonoids as key bioactive components of Oxytropis falcata bunge, a traditional anti-inflammatory and analgesic Tibetan medicine. NATURAL PRODUCT RESEARCH[J]. 2020, 第 3 作者34(23): 3335-3352, https://www.webofscience.com/wos/woscc/full-record/WOS:000594432300005.
[35] Wang, Jun, Li, CaiHong, Farimani, Mahdi Moridi, Yang, JunLi. Dammarane-type saponins from Gynostemma pentaphyllum and their potential anti-AD activity. PHYTOCHEMISTRY LETTERS[J]. 2019, 第 4 作者 通讯作者 31: 147-154, http://dx.doi.org/10.1016/j.phytol.2019.03.022.
[36] Yang, JunLi, Trong Tuan Dao, Tran Thi Hien, Zhao, YaMin, Shi, YanPing. Further sesquiterpenoids from the rhizomes of Homalomena occulta and their anti-inflammatory activity. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS[J]. 2019, 第 1 作者29(10): 1162-1167, http://dx.doi.org/10.1016/j.bmcl.2019.03.031.
[37] JunLiYang, LeiLeiLiu, YanPingShi. Two New Eudesmane Sesquiterpenoids from the Flowers ofChrysanthemum indicum. Natural Products and Bioprospecting[J]. 2019, 第 1 作者9(2): 145-148, http://npb.kib.ac.cn/EN/10.1007/s13659-019-0199-9.
[38] Thi Kim Quy Ha, Ha Thanh Tung Pham, Cho, Hyo Moon, Van On Tran, Yang, JunLi, Jung, DaWoon, Williams, Darren R, Oh, Won Keun. 12,23-Dione dammarane triterpenes from Gynostemma longipes and their muscle cell proliferation activities via activation of the AMPK pathway. SCIENTIFIC REPORTS[J]. 2019, 第 5 作者9(1): https://doaj.org/article/4414e2b03d8e41a8a13597eb79759011.
[39] Wang, YanMing, Zhao, JianQiang, Yang, JunLi, Idong, Pema Tsering, Mei, LiJuan, Tao, YanDuo, Shi, YanPing. Antioxidant and alpha-glucosidase inhibitory ingredients identified from Jerusalem artichoke flowers. NATURAL PRODUCT RESEARCH[J]. 2019, 第 3 作者33(4): 584-588,
[40] Ding, YuZhu, Wang, WeiFeng, Chai, Tian, Qiang, Yin, Shi, YanPing, Yang, JunLi. Ratiometric target-triggered fluorescent silicon nanoparticles probe for quantitative visualization of tyrosinase activity. TALANTA[J]. 2019, 第 6 作者 通讯作者 197: 113-121, http://210.77.64.217/handle/362003/24922.
[41] Wang, WeiFeng, Yang, JunLi. Advances in screening enzyme inhibitors by capillary electrophoresis. ELECTROPHORESIS. 2019, 第 2 作者 通讯作者 40(16-17): 2075-2083, https://www.webofscience.com/wos/woscc/full-record/WOS:000478750500007.
[42] Li, CaiHong, Meng, XianHua, Huong, Dang Lan, Oh, Won Keun, Wang, WeiFeng, Yang, JunLi. Quantitative visualization and detection of acetylcholinesterase activity and its inhibitor based on the oxidation character of ultrathin MnO2 nanosheets. ANALYTICAL METHODS[J]. 2019, 第 6 作者 通讯作者 11(38): 4931-4938,
[43] JunLi Yang. Ratiometric Target-Triggered Fluorescence Silicon Nanoparticles Probe for Quantitative Visulization of Tyrosinase Activity. Talanta. 2019, 第 1 作者 通讯作者
[44] 张弦飞, 杨军丽, 陈娟, 师彦平. 超高效合相色谱-串联质谱法快速测定枸杞中甜菜碱含量. 色谱[J]. 2018, 第 2 作者36(5): 417-424, http://lib.cqvip.com/Qikan/Article/Detail?id=675273824.
[45] Zhang, XianFei, Chen, Juan, Yang, JunLi, Shi, YanPing. UPLC-MS/MS analysis for antioxidant components of Lycii Fructus based on spectrum-effect relationship. TALANTA[J]. 2018, 第 3 作者 通讯作者 180: 389-395, http://dx.doi.org/10.1016/j.talanta.2017.12.078.
[46] Wang, WeiFeng, Qiang, Yin, Meng, XianHua, Yang, JunLi, Shi, YanPing. Ultrasensitive colorimetric assay melamine based on in situ reduction to formation of CQDs-silver nanocomposite. SENSORS AND ACTUATORS B-CHEMICAL[J]. 2018, 第 4 作者 通讯作者 260: 808-815, http://dx.doi.org/10.1016/j.snb.2018.01.108.
[47] 王君, 孟宪华, 王伟峰, 赵晓博, 李彩虹, 杨军丽, 师彦平. 抗AD活性天然化合物的结构与功能. 中国科学:化学[J]. 2018, 第 6 作者48(12): 1452-1465, http://lib.cqvip.com/Qikan/Article/Detail?id=6100232596.
[48] Qi, Xuan, Wang, WeiFeng, Wang, Jun, Yang, JunLi, Shi, YanPing. Highly selective colorimetric detection of putrescine in fish products using o-phthalaldehyde derivatization reaction. FOOD CHEMISTRY[J]. 2018, 第 4 作者 通讯作者 259: 245-250, http://dx.doi.org/10.1016/j.foodchem.2018.03.131.
[49] Wang, WeiFeng, Qiang, Yin, Meng, XianHua, Yang, JunLi, Shi, YanPing. Ultrasensitive colorimetric assay melamine based on in situ reduction to formation of CQDs-silver nanocomposite. SENSORS AND ACTUATORS B-CHEMICAL[J]. 2018, 第 4 作者 通讯作者 260: 808-815, http://dx.doi.org/10.1016/j.snb.2018.01.108.
[50] Wang, WeiFeng, Yang, JunLi, Shi, YanPing. Quality evaluation of six bioactive constituents in goji berry based on capillary electrophoresis field amplified sample stacking. ELECTROPHORESIS[J]. 2018, 第 11 作者39(16): 2117-2124, http://210.77.64.217/handle/362003/24657.
[51] Wang, Jun, Ha, Thi Kim Quy, Shi, YanPing, Oh, Won Keun, Yang, JunLi. Hypoglycemic triterpenes from Gynostemma pentaphyllum. PHYTOCHEMISTRY[J]. 2018, 第 5 作者 通讯作者 155(155): 171-181, http://dx.doi.org/10.1016/j.phytochem.2018.08.008.
[52] Zhang Xianfei, Yang Junli, Chen Juan, Shi Yanping. 超高效合相色谱-串联质谱法快速测定枸杞中甜菜碱含量. 色谱[J]. 2018, 第 2 作者36(5): 417-424, http://lib.cqvip.com/Qikan/Article/Detail?id=675273824.
[53] Wang, Jun, Yang, JunLi, Zhou, PanPan, Meng, XianHua, Shi, YanPing. Further New Gypenosides from Jiaogulan (Gynostemma pentaphyllum). JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2017, 第 2 作者 通讯作者 65(29): 5926-5934, http://ir.licp.ac.cn/handle/362003/22440.
[54] Kim Ji Won, Ha ThiKimQuy, Cho Hyomoon, Kim Eunhee, Shim Sang Hee, Yang JunLi, Oh Won Keun. Antiviral escin derivatives from the seeds of Aesculus turbinata Blume (Japanese horse chestnut). BIOORGANIC & MEDICINAL CHEMISTRY LETTERS[J]. 2017, 第 6 作者
[55] Wang, YanMing, Zhao, JianQiang, Yang, JunLi, Tao, YanDuo, Mei, LiJuan, Shi, YanPing. Chemical constituents from Ligularia purdomii (Turrill) Chittenden. BIOCHEMICAL SYSTEMATICS AND ECOLOGY[J]. 2017, 第 3 作者72: 8-11, http://dx.doi.org/10.1016/j.bse.2017.03.007.
[56] Jiang, HaiLong, Yang, JunLi, Shi, YanPing. Optimization of ultrasonic cell grinder extraction of anthocyanins from blueberry using response surface methodology. ULTRASONICS SONOCHEMISTRY[J]. 2017, 第 2 作者 通讯作者 34: 325-331, http://dx.doi.org/10.1016/j.ultsonch.2016.06.003.
[57] Kim, Ji Won, Ha, ThiKimQuy, Cho, Hyomoon, Kim, Eunhee, Shim, Sang Hee, Yang, JunLi, Oh, Won Keun. Antiviral escin derivatives from the seeds of Aesculus turbinata Blume (Japanese horse chestnut). BIOORGANIC & MEDICINAL CHEMISTRY LETTERS[J]. 2017, 第 6 作者27(13): 3019-3025, http://dx.doi.org/10.1016/j.bmcl.2017.05.022.
[58] Wang, Pei, Yang, Junli, Yerke, Aaron, Sang, Shengmin. Avenacosides: Metabolism, and potential use as exposure biomarkers of oat intake. MOLECULAR NUTRITION & FOOD RESEARCH[J]. 2017, 第 2 作者61(7): https://www.webofscience.com/wos/woscc/full-record/WOS:000404730400013.
[59] Wang Jun, Yang JunLi, Zhou PanPan, Meng XianHua, Shi YanPing. Further New Gypenosides from Jiaogulan ( Gynostemma pentaphyllum ). JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2017, 第 2 作者
[60] Wang, YanMing, Zhao, JianQiang, Yang, JunLi, Tao, YanDuo, Mei, LiJuan, Shi, YanPing. Separation of antioxidant and -glucosidase inhibitory flavonoids from the aerial parts of Asterothamnus centrali-asiaticus. NATURAL PRODUCT RESEARCH[J]. 2017, 第 3 作者31(12): 1365-1369, http://210.75.249.4/handle/363003/6830.
[61] Yang, Jun Li, Thi Kim Quy Ha, Lee, Ba Wool, Kim, Jinwoong, Oh, Won Keun. PTP1B inhibitors from the seeds of Iris sanguinea and their insulin mimetic activities via AMPK and ACC phosphorylation. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS[J]. 2017, 第 1 作者27(22): 5076-5081, http://dx.doi.org/10.1016/j.bmcl.2017.09.031.
[62] Nguyen PhiHung, Choi Hong Seok, Ha Thi Kim Quy, Seo Ji Yeon, Yang JunLi, Jung DaWoon, Williams Darren R, Oh WonKeun. Anthraquinones from Morinda longissima and their insulin mimetic activities via AMP-activated protein kinase (AMPK) activation. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS[J]. 2017, 第 5 作者
[63] Qiang, Yin, Wang, WeiFeng, Dhodary, Basanta, Yang, JunLi. Zeolitic imidazolate framework 8 (ZIF-8) reinforced macroporous resin D101 for selective solid-phase extraction of 1-naphthol and 2-naphthol from phenol compounds. ELECTROPHORESIS[J]. 2017, 第 4 作者 通讯作者 38(13-14): 1685-1692, https://www.webofscience.com/wos/woscc/full-record/WOS:000406724100004.
[64] Zhao, XiaoBo, Ha, Wei, Jiang, Kan, Chen, Juan, Yang, JunLi, Shi, YanPing. Efficient synthesis of camptothecin propargylamine derivatives in water catalyzed by macroporous adsorption resin-supported gold nanoparticles. GREEN CHEMISTRY[J]. 2017, 第 5 作者19(5): 1399-1406, http://www.irgrid.ac.cn/handle/1471x/1181113.
[65] Liu, LeiLei, Ha, Thi Kim Quy, Ha, Wei, Oh, Won Keun, Yang, JunLi, Shi, YanPing. Sesquiterpenoids with Various Carbocyclic Skeletons from the Flowers of Chrysanthemum indicum. JOURNAL OF NATURAL PRODUCTS[J]. 2017, 第 5 作者 通讯作者 80(2): 298-307, http://www.irgrid.ac.cn/handle/1471x/1181105.
[66] Liu, DongMei, Yang, JunLi, Ha, Wei, Chen, Juan, Shi, YanPing. Kinetics and inhibition study of tyrosinase by pressure mediated microanalysis. ANALYTICAL BIOCHEMISTRY[J]. 2017, 第 2 作者525: 54-59, http://dx.doi.org/10.1016/j.ab.2017.02.020.
[67] Zhang, XianFei, Yang, JunLi, Chen, Juan, Shi, YanPing. Optimization of a Decoction Process for an Herbal Formula Using a Response Surface Methodology. JOURNAL OF AOAC INTERNATIONAL[J]. 2017, 第 2 作者100(6): 1776-1784, http://ir.licp.ac.cn/handle/362003/22857.
[68] Ji Won Kim, ThiKimQuy Ha, Hyomoon Cho, Eunhee Kim, Sang Hee Shim, 杨军丽, Won Keun Oh. Antiviral escin derivatives from the seeds of Aesculus turbinata Blume (Japanese horse chestnut). BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS[J]. 2017, 第 6 作者27(13): 3019-3025, http://dx.doi.org/10.1016/j.bmcl.2017.05.022.
[69] Yang, Jun Li, Thi Kim Quy Ha, Dhodary, Basanta, Seo, Ji Yeon, Kim, Hyunju, Park, Junsoo, Oh, Won Keun. 3,4-seco-28-Nor-oleanane triterpenes from Camellia japonica protect from neurotoxicity in a rotenone model of Parkinson's disease. TETRAHEDRON[J]. 2016, 第 1 作者72(23): 3240-3249, http://dx.doi.org/10.1016/j.tet.2016.04.045.
[70] Wang, YanMing, Zhao, JianQiang, Zhou, ShuangYan, Yang, JunLi, Yao, XiaoJun, Tao, YanDuo, Mei, LiJuan, Shi, YanPing. New sesquiterpenes and benzofuran derivatives from the aerial parts of Asterothamnus centrali-asiaticus. TETRAHEDRON[J]. 2016, 第 4 作者72(32): 4910-4917, http://dx.doi.org/10.1016/j.tet.2016.06.061.
[71] Yang, ChunYan, Ha, Wei, Lin, Yong, Jiang, Kan, Yang, JunLi, Shi, YanPing. Polyphenols Isolated from Xanthoceras sorbifolia Husks and Their Anti-Tumor and Radical-Scavenging Activities. MOLECULES[J]. 2016, 第 5 作者 通讯作者 21(12): http://www.irgrid.ac.cn/handle/1471x/1143176.
[72] Wang, YanMing, Zhao, JianQiang, Yang, JunLi, Tao, YanDuo, Mei, LiJuan, Shi, YanPing. Isolation and Identification of Saponins from the Natural Pasturage Asterothamnus centrali-asiaticus Employing Preparative Two-Dimensional Reversed-Phase Liquid Chromatography/Hydrophilic Interaction Chromatography. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2016, 第 3 作者64(24): 4950-4957, http://210.75.249.4/handle/363003/6481.
[73] Yang, Junli, Wang, Pei, Wu, Wenbin, Zhao, Yantao, Idehen, Emmanuel, Sang, Shengmin. Steroidal Saponins in Oat Bran. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2016, 第 1 作者64(7): 1549-1556, http://dx.doi.org/10.1021/acs.jafc.5b06071.
[74] Jiang, HaiLong, Ha, Wei, Yang, JunLi, Shi, YanPing. New sesquiterpene polyol esters from the root bark of Pseudolarix kaempferi. PHYTOCHEMISTRY LETTERS[J]. 2016, 第 3 作者 通讯作者 17: 1-5, http://dx.doi.org/10.1016/j.phytol.2016.06.004.
[75] JunLi Yang. New sesquiterpene polyol esters from the root barks of Pseudolarix kaempferi. Phytochemistry Letters. 2016, 第 1 作者 通讯作者
[76] Yang, JunLi, ThiKimQuy Ha, Dhodary, Basanta, Pyo, Euisun, Ngoc Hieu Nguyen, Cho, Hyomoon, Kim, Eunhee, Oh, Won Keun. Oleanane Triterpenes from the Flowers of Camellia japonica Inhibit Porcine Epidemic Diarrhea Virus (PEDV) Replication. JOURNALOFMEDICINALCHEMISTRY[J]. 2015, 第 1 作者58(3): 1268-1280, https://www.webofscience.com/wos/woscc/full-record/WOS:000349573800019.
[77] Yang, JunLi, Dhodary, Basanta, Ha, Thi Kim Quy, Kim, Jinwoong, Kim, Eunhee, Oh, Won Keun. Three new coumarins from Saposhnikovia divaricata and their porcine epidemic diarrhea virus (PEDV) inhibitory activity. TETRAHEDRON[J]. 2015, 第 1 作者71(28): 4651-4658, http://dx.doi.org/10.1016/j.tet.2015.04.092.
[78] Yang, JunLi, Ha, ThiKimQuy, Dhodary, Basanta, Kim, KukHwa, Park, Junsoo, Lee, ChulHo, Kim, YoungChoong, Oh, WonKeun. Dammarane Triterpenes as Potential SIRT1 Activators from the Leaves of Panax ginseng. JOURNAL OF NATURAL PRODUCTS[J]. 2014, 第 1 作者77(7): 1615-1623, https://www.webofscience.com/wos/woscc/full-record/WOS:000339604300010.
[79] Yang, JunLi, Shi, YanPing. Cycloartane-type triterpenoids and sesquiterpenoids from the resinous exudates of Commiphora opobalsamum. PHYTOCHEMISTRY[J]. 2012, 第 1 作者76: 124-132, http://dx.doi.org/10.1016/j.phytochem.2012.01.004.
[80] Liu Leilei, Wang Rui, Yang Junli, Shi Yanping. Five New Sesquiterpenoids from Chrysanthemum indicum. 中国化学:英文版[J]. 2012, 第 3 作者30(6): 1255-1260, http://lib.cqvip.com/Qikan/Article/Detail?id=42601396.
[81] Jiang, HaiLong, Luo, XiaoHong, Wang, XiaoZheng, Yang, JunLi, Yao, XiaoJun, Crews, Phillip, Valeriote, Frederick A, Wu, QuanXiang. New isocoumarins and alkaloid from Chinese insect medicine, Eupolyphaga sinensis Walker. FITOTERAPIA[J]. 2012, 第 4 作者83(7): 1275-1280, http://dx.doi.org/10.1016/j.fitote.2012.06.005.
[82] Liu Leilei, Wang Rui, Yang Junli, Shi Yanping. Five New Sesquiterpenoids from Chrysanthemum indicum. CHINESE JOURNAL OF CHEMISTRY[J]. 2012, 第 3 作者30(6): 1255-1260, http://lib.cqvip.com/Qikan/Article/Detail?id=42601396.
[83] Yang, JunLi, Shi, YanPing. Structurally Diverse Terpenoids from the Rhizomes of Cyperus rotundus L.. PLANTA MEDICA[J]. 2012, 第 1 作者78(1): 59-64, http://www.irgrid.ac.cn/handle/1471x/1030184.
[84] Qiang, Yin, Yang, ZhongDuo, Yang, JunLi, Gao, Kun. Sesquiterpenoids from the Root Tubers of Lindera aggregata. PLANTA MEDICA[J]. 2011, 第 3 作者77(14): 1610-1616, https://www.webofscience.com/wos/woscc/full-record/WOS:000295806000010.
[85] Liu, LeiLei, Yang, JunLi, Shi, YanPing. Sesquiterpenoids and other constituents from the flower buds of Tussilago farfara. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH[J]. 2011, 第 2 作者13(10): 920-929, http://www.irgrid.ac.cn/handle/1471x/521118.
[86] Yang, JunLi, Liu, LeiLei, Shi, YanPing. Limonoids and Quinoline Alkaloids from Dictamnus dasycarpus. PLANTA MEDICA[J]. 2011, 第 1 作者77(3): 271-276, http://www.irgrid.ac.cn/handle/1471x/521115.
[87] Gong, HaiQun, Wu, QuanXiang, Liu, LeiLei, Yang, JunLi, Wang, Rui, Shi, YanPing. Sesquiterpenoids from the Aerial Parts of Inula japonica. HELVETICA CHIMICA ACTA[J]. 2011, 第 4 作者94(7): 1269-1276, http://dx.doi.org/10.1002/hlca.201000417.
[88] Yang, JunLi, Wang, Rui, Liu, LeiLei, Shi, YanPing. Sesquiterpenoids from Inula britannica. PLANTA MEDICA[J]. 2011, 第 1 作者77(4): 362-367, http://www.irgrid.ac.cn/handle/1471x/521116.
[89] 龚海群, 武全香, 刘磊磊, 杨军丽, 王瑞, 师彦平. Sesquiterpenoids from the aerial parts of Inula japonica. HEIVETICA CHIMICA ACTA[J]. 2011, 第 4 作者94: 1269-1276, http://www.irgrid.ac.cn/handle/1471x/521117.
[90] Liu, LeiLei, Wang, Rui, Yang, JunLi, Shi, YanPing. Diversity of Sesquiterpenoids from Carpesium cernuum. HELVETICA CHIMICA ACTA[J]. 2010, 第 3 作者93(3): 595-601, http://www.irgrid.ac.cn/handle/1471x/516053.
[91] Yang, JunLi, Liu, LeiLei, Wang, BinGui, Shi, YanPing. Secondary metabolites from Grateloupia turuturu and their chemotaxonomic significance. BIOCHEMICAL SYSTEMATICS AND ECOLOGY[J]. 2010, 第 1 作者38(4): 850-852, http://dx.doi.org/10.1016/j.bse.2010.07.015.
[92] Yang, JunLi, Wang, Rui, Liu, LeiLei, Shi, YanPing. Phytochemicals and biological activities of Saussurea species. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH. 2010, 第 1 作者12(2): 162-175, https://www.webofscience.com/wos/woscc/full-record/WOS:000277569800012.
[93] Liu, LeiLei, Yang, JunLi, Shi, YanPing. Phytochemicals and Biological Activities of Pulicaria Species. CHEMISTRY & BIODIVERSITY. 2010, 第 2 作者7(2): 327-349, https://www.webofscience.com/wos/woscc/full-record/WOS:000275184800005.
[94] 刘磊磊, 王瑞, 杨军丽, 师彦平. Diversity of Sesquiterpenoids from Carpesium cernuum. HELV. CHIM. ACTA[J]. 2010, 第 3 作者93: 595-601, http://www.irgrid.ac.cn/handle/1471x/516053.
[95] 王瑞, 杨军丽, 刘磊磊, 师彦平. 西部特色中药倍半萜和二萜成分的研究. 中国化学会第八届天然有机化学学术研讨会论文集. 2010, 第 2 作者91, http://www.irgrid.ac.cn/handle/1471x/521195.
[96] Yang, JunLi, Liu, LeiLei, Shi, YanPing. Phytochemicals and Biological Activities of Gentiana Species. NATURAL PRODUCT COMMUNICATIONS. 2010, 第 1 作者5(4): 649-664, https://www.webofscience.com/wos/woscc/full-record/WOS:000276598500032.
[97] Yang, JunLi, Liu, LieLie, Shi, YanPing. Britanlins A-D, four novel sesquiterpenoids from Inula britannica. TETRAHEDRON LETTERS[J]. 2009, 第 1 作者50(46): 6315-6317, http://dx.doi.org/10.1016/j.tetlet.2009.08.129.
[98] 杨军丽, 刘磊磊, 师彦平. Britanlins A-D, four novel sesquiterpenoids from Inula britannica. TETRAHEDRON LETT.[J]. 2009, 第 1 作者50: 6315-6317, http://dx.doi.org/10.1016/j.tetlet.2009.08.129.
[99] JiaLin Wang, XianHua Meng, YiDan Zheng, ChunYan Sang, WeiFeng Wang, JunYi Ma, ThiKimQuy Ha, YaMin Zhao, JunLi Yang. (±)-Ferulasin, unusual sesquiterpene chromones from Ferula sinkiangensis. TETRAHEDRON. 第 9 作者http://dx.doi.org/10.1016/j.tet.2022.132953.
科研活动
1. 国家重点研发计划 “基于中伊传统草药的抗AD药物候选化合物研究”(主持,2018YFE0182500)
2. 中国科学院“率先行动****”人才项目:“植物源活性天然产物的快速发现与应用”(主持)
3. 国家自然科学基金面上项目“基于超滤质谱和超低温探头NMR技术的三种花椒属植物中SIRT1抑制剂的快速发现及其抗肿瘤活性研究”( 主持,81673325)
科研项目
( 2 ) 基于超滤质谱和超低温探头NMR技术的三种花椒属植物中SIRT1抑制剂的快速发现及其抗肿瘤活性研究, 主持, 国家级, 2017-01--2020-12
( 3 ) "一带一路”民族药研发与产业化合作, 参与, 部委级, 2016-01--2020-12
( 4 ) 中韩药用植物抗衰老活性分子研究, 主持, 国家级, 2017-07--2019-06
( 5 ) 甘肃花椒活性成分发现与宏量制备关键技术一带一路国际科技合作研究, 参与, 省级, 2018-07--2020-06
( 6 ) 中科院2019年度特别交流计划项目“中亚植物药研究(A类)”, 主持, 部委级, 2019-01--2020-12
( 7 ) 基于西北特色植物资源的改善认知损伤的药物筛选与评价, 主持, 研究所(学校), 2019-01--2021-12
参与会议
(2)中药萜类化学成分发现与活性评价 中国化学会第十届全国有机化学学术会议 杨军丽 2017-12-19
(3)Chemical Constitutes and Biological Activities of TCMs 第十二届天然化合物化学国际研讨会 2017-09-06
(4)Chemical Constitutes and Biological Activities on TCMs 第五届可食和药用植物资源及功能成分国际学术研讨会 2016-11-04
(5)Bioactive Natural Products from Medicinal Plants 天然产物分离分析新技术国际学术研讨会 2016-11-04
(6)植物源天然化合物的发现与生物活性研究 中国化学会第十一届全国天然有机化学学术会议 2016-09-25
指导学生
已指导学生
祁轩 硕士研究生 070303-有机化学
王君 博士研究生 070302-分析化学
现指导学生
李彩虹 硕士研究生 070302-分析化学
马丽梅 硕士研究生 070302-分析化学
陶璐瑶 硕士研究生 085235-制药工程
丁玉竹 博士研究生 070302-分析化学
马丽 硕士研究生 070302-分析化学
王凯 博士研究生 070302-分析化学
张瑛 博士研究生 070302-分析化学