图文多模态大模型，视觉基座大模型，大模型的临床应用，影像组学，多组学

对大模型基础算法研究及其临床应用有浓厚兴趣的同学，欢迎加入课题组。

081104-模式识别与智能系统
083100-生物医学工程
0812J3-生物信息学

智能生物医学影像
影像组学与多组学
医学影像大模型

2014-07--2019-06   中国科学院大学   博士学位

   

2021-07~现在, 中国科学院自动化研究所, 副研究员
2019-07~2021-07,中国科学院自动化研究所, 助理研究员

2024-04-30-今,Lancet Digital Health, 审稿人
2023-06-15-今,海峡两岸医药卫生交流协会肿瘤学分会, 青年副主任委员
2023-06-08-今,中国人工智能学会智能光学成像专业委员会, 委员
2023-01-01-今,IEEE JBHI, 审稿人
2023-01-01-今,Digestive Liver Disease, 审稿人
2023-01-01-今,Advanced Science, 审稿人
2022-12-31-今,《iLiver》期刊, 青年编委
2022-07-29-今,《工医艺的可视计算（英文）》期刊, 青年编委

   

（1） Evolving strategies in the diagnosis and treatment of HIV-associated neurocognitive disorders, REVIEWS IN THE NEUROSCIENCES, 2025, 第 2 作者
（2） Noninvasive prognostic classification of ITH in HCC with multi-omics insights and therapeutic implications, SCIENCE ADVANCES, 2025, 第 3 作者
（3） Multi-omics synergy in oncology: Unraveling the complex interplay of radiomic, genoproteomic, and pathological data, Intelligent Oncology, 2024, 第 9 作者  通讯作者
（4） Adaptive Multiphase Liver Tumor Segmentation With Multiscale Supervision, IEEE SIGNAL PROCESSING LETTERS, 2024, 第 4 作者  通讯作者
（5） Large scale models in radiology: revolutionizing the future of medical imaging, Radiology Science, 2024, 第 4 作者
（6） 影像组学创新技术驱动肝脏外科发展, Radiomics innovation drives the development of hepatic surgery, 中国医学前沿杂志:电子版, 2022, 第 4 作者
（7） Advances in artificial intelligence techniques drive the application of radiomics in the clinical research of hepatocellular carcinoma, Advances in artificial intelligence techniques drive the application of radiomics in the clinical research of hepatocellular carcinoma, 国际肝胆健康(英文), 2022, 第 1 作者
（8） Radiomics-Based Preoperative Prediction of Lymph Node Metastasis in Intrahepatic Cholangiocarcinoma Using Contrast-Enhanced Computed Tomography, ANNALS OF SURGICAL ONCOLOGY, 2022, 第 4 作者
（9） ASO Visual Abstract: Radiomics-Based Preoperative Prediction of Lymph Node Metastasis in Intrahepatic Cholangiocarcinoma Using Contrast-Enhanced Computed Tomography, ANNALS OF SURGICAL ONCOLOGY, 2022, 第 4 作者
（10） CT-based radiomics to predict development of macrovascular invasion in hepatocellular carcinoma:A multicenter study, CT���based radiomics to predict development of macrovascular invasion in hepatocellular carcinoma: A multicenter study, HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL, 2022, 第 1 作者
（11） A multi-scale, multi-region and attention mechanism-based deep learning framework for prediction of grading in hepatocellular carcinoma, MEDICAL PHYSICS, 2022, 第 1 作者
（12） Predicting microvascular invasion in hepatocellular carcinoma: A dual-institution study on gadoxetate disodium-enhanced MRI, LIVER INTERNATIONAL, 2022, 第 2 作者
（13） Advances in artificial intelligence techniques drive the application of radiomics in the clinical research of hepatocellular carcinoma, ILIVER, 2022, 第 1 作者
（14） Radiomics: A radiological evidence-based artificial intelligence technique to facilitate personalized precision medicine in hepatocellular carcinoma, DIGESTIVE AND LIVER DISEASE, 2022, 第 1 作者
（15） 多组学技术及其在肝细胞癌中的临床应用：当前进展与未来机遇, Multi-Omics and Its Clinical Application in Hepatocellular Carcinoma:Current Progress and Future Opportunities, 中国医学科学杂志:英文版, 2021, 第 4 作者
（16） Multi-Omics and Its Clinical Application in Hepatocellular Carcinoma: Current Progress and Future Opportunities, CHINESE MEDICAL SCIENCES JOURNAL, 2021, 第 4 作者
（17） The Role of Imaging in the Detection and Management of COVID-19: A Review, IEEE REVIEWS IN BIOMEDICAL ENGINEERING, 2021, 第 14 作者
（18） Prediction of Microvascular Invasion in Hepatocellular Carcinoma via Deep Learning: A Multi-Center and Prospective Validation Study, CANCERS, 2021, 第 1 作者
（19） Radiomics diagnosed histopathological growth pattern in prediction of response and 1-year progression free survival for colorectal liver metastases patients treated with bevacizumab containing chemotherapy, EUROPEAN JOURNAL OF RADIOLOGY, 2021, 第 7 作者
（20） A model based on clinico-biochemical characteristics and deep learning features from MR images for assessing necroinflammatory activity in chronic hepatitis B, JOURNAL OF VIRAL HEPATITIS, 2021, 第 3 作者
（21） Deep learning-based radiomics predicts response to chemotherapy in colorectal liver metastases, MEDICAL PHYSICS, 2021, 第 1 作者
（22） Radiomics in liver diseases: Current progress and future opportunities, LIVER INTERNATIONAL, 2020, 第 1 作者
（23） NONINVASIVE PREDICTION OF RECURRENCE-FREE SURVIVAL AFTER SURGICAL RESECTION IN INTRAHEPATIC CHOLANGIOCARCINOMA: A MULTICENTER RADIOMICS STUDY, HEPATOLOGY, 2020, 第 1 作者
（24） Improving B-mode ultrasound diagnostic performance for focal liver lesions using deep learning: A multicentre study, EBIOMEDICINE, 2020, 第 2 作者
（25） Radiomics Based on MRI as a Biomarker to Guide Therapy by Predicting Upgrading of Prostate Cancer From Biopsy to Radical Prostatectomy, JOURNAL OF MAGNETIC RESONANCE IMAGING, 2020, 第 3 作者
（26） Multiparametric MRI-Based Radiomics for Prostate Cancer Screening With PSA in 4-10 ng/mL to Reduce Unnecessary Biopsies, JOURNAL OF MAGNETIC RESONANCE IMAGING, 2020, 第 3 作者
（27） 影像组学研究进展及其在肝癌中的临床应用, Research progress and clinical application of radiomics in hepatocellular carcinoma, 中国科学: 生命科学, 2020, 第 2 作者
（28） A radiomics-based biomarker for cytokeratin 19 status of hepatocellular carcinoma with gadoxetic acid-enhanced MRI, EUROPEAN RADIOLOGY, 2020, 第 3 作者
（29） DEEP LEARNING RADIOMICS FOR PREOPERATIVE PREDICTION OF MICROVASCULAR INVASION IN HEPATOCELLULAR CARCINOMA: A MULTICENTER AND PROSPECTIVE VALIDATION STUDY, HEPATOLOGY, 2020, 第 1 作者
（30） Identification of Predominant Histopathological Growth Patterns of Colorectal Liver Metastasis by Multi-Habitat and Multi-Sequence Based Radiomics Analysis, FRONTIERS IN ONCOLOGY, 2020, 第 3 作者
（31） MRI-Based Radiomics Signature: A Potential Biomarker for Identifying Glypican 3-Positive Hepatocellular Carcinoma, JOURNAL OF MAGNETIC RESONANCE IMAGING, 2020, 第 3 作者
（32） Accurate Preoperative Distinction of Intracranial Hemangiopericytoma From Meningioma Using a Multihabitat and Multisequence-Based Radiomics Diagnostic Technique, FRONTIERS IN ONCOLOGY, 2020, 第 1 作者
（33） Preoperative radiomics nomogram for microvascular invasion prediction in hepatocellular carcinoma using contrast-enhanced ct, EUROPEAN RADIOLOGY, 2019, 第 2 作者
（34） Radiomics Facilitates Candidate Selection for Irradiation Stents Among Patients With Unresectable Pancreatic Cancer, FRONTIERS IN ONCOLOGY, 2019, 第 4 作者
（35） Development and validation of a radiomics-based method for macrovascular invasion prediction in hepatocellular carcinoma with prognostic implication, MEDICAL IMAGING 2019: COMPUTER-AIDED DIAGNOSIS, 2019, 第 1 作者
（36） Prediction of Histopathologic Growth Patterns of Colorectal Liver Metastases with a Noninvasive Imaging Method, ANNALS OF SURGICAL ONCOLOGY, 2019, 第 2 作者
（37） Prediction early recurrence of hepatocellular carcinoma eligible for curative ablation using a Radiomics nomogram, CANCER IMAGING, 2019, 第 6 作者
（38） CT radiomics may predict the grade of pancreatic neuroendocrine tumors: a multicenter study, EUROPEAN RADIOLOGY, 2019, 第 4 作者
（39） Development and validation of a radiomics-based method for macrovascular invasion prediction in hepatocellular carcinoma with prognostic implication, 2019, 第 11 作者
（40） Pretreatment prediction of immunoscore in hepatocellular cancer: a radiomics-based clinical model based on Gd-EOB-DTPA-enhanced MRI imaging, EUROPEAN RADIOLOGY, 2019, 第 3 作者
（41） Selection Between Liver Resection Versus Transarterial Chemoembolization in Hepatocellular Carcinoma: A Multicenter Study, CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, 2019, 第 2 作者
（42） Non-invasive genotype prediction of chromosome 1p/19q co-deletion by development and validation of an MRI-based radiomics signature in lower-grade gliomas, MEDICAL IMAGING 2019: COMPUTER-AIDED DIAGNOSIS, 2019, 第 6 作者
（43） The Applications of Radiomics in Precision Diagnosis and Treatment of Oncology: Opportunities and Challenges, THERANOSTICS, 2019, 第 4 作者
（44） A multi-sequence and habitat-based MRI radiomics signature for preoperative prediction of MGMT promoter methylation in astrocytomas with prognostic implication, EUROPEAN RADIOLOGY, 2019, 第 1 作者
（45） Radiomics analysis enables recurrence prediction for hepatocellular carcinoma after liver transplantation, EUROPEAN JOURNAL OF RADIOLOGY, 2019, 第 4 作者
（46） A radiomics nomogram may improve the prediction of idh genotype for astrocytoma before surgery, EUROPEAN RADIOLOGY, 2019, 第 3 作者
（47） A Radiomics Nomogram for Preoperative Prediction of Microvascular Invasion in Hepatocellular Carcinoma, LIVER CANCER, 2019, 第 3 作者
（48） Preoperative prediction of microvascular invasion in hcc using radiomics on multisequence gadoxetic acid-enhanced mr images, CANCER RESEARCH, 2018, 第 1 作者
（49） Non-invasive genotype prediction of chromosome 1p/19q co-deletion by development and validation of an mri-based radiomics signature in lower-grade gliomas, JOURNAL OF NEURO-ONCOLOGY, 2018, 第 8 作者
（50） Mr-based radiomics signature as surrogate of hepatic venous pressure gradient for clinically significant portal hypertension in advanced chronic liver disease: a prospective multicenter study, HEPATOLOGY, 2018, 第 12 作者
（51） Radiomics analysis allows for precise prediction of epilepsy in patients with low-grade gliomas, NEUROIMAGE-CLINICAL, 2018, 第 7 作者
（52） Diagnostic Accuracy of Radiomics-based Hepatic Venous Pressure Gradient for Clinically Significant Portal Hypertension in Cirrhosis, HEPATOLOGY, 2017, 第 9 作者
（53） Radiomics analysis enables response prediction for hepatocellular carcinoma after liver transplantation, EUROPEAN JOURNAL OF RADIOLOGY, 第 4 作者

（1） Radiomics in medical imaging—detection, extraction and segmentation, Springer, 2017-10, 第 5 作者
（2） Radiomics and Its Clinical Application: Artificial Intelligence and Medical Big Data, Elsevier, 2021-07, 第 4 作者

   

（ 1 ） 消化肿瘤多维度信息HFRT动态数据库平台的构建和应用, 负责人, 国家任务, 2023-01--2025-12
（ 2 ） 多维组学和病理特征交互的肝细胞癌影像预后分型关键问题研究, 负责人, 国家任务, 2023-01--2027-12
（ 3 ） 靶向FABP4的载药纳米成像探针在胆管癌淋巴结转移的诊断与治疗中的应用研究, 负责人, 地方任务, 2023-01--2026-12
（ 4 ） 融合超声影像组学和lncRNA转录组学多维信息辅助中晚期肝癌精准诊疗的方法研究, 负责人, 国家任务, 2023-01--2027-12
（ 5 ） 肝癌肝移植诊疗关键分子智能可视化研究, 负责人, 国家任务, 2022-01--2025-12
（ 6 ） 常见恶性肿瘤多维度早诊精准成像技术的研发, 负责人, 国家任务, 2022-01--2024-12
（ 7 ） 基于多模态影像组学和液态活检多组学的肝门胆管癌人工智能辅助HAIC疗效预测和评效模型研究, 负责人, 国家任务, 2022-01--2025-12
（ 8 ） 肝癌智能化精准外科的共性关键技术体系的建立, 负责人, 国家任务, 2021-01--2025-12
（ 9 ） 基于深度学习影像组学的肝细胞癌微血管侵犯预测研究, 负责人, 国家任务, 2021-01--2023-12
（ 10 ） 基于深度学习影像组学方法的脑膜瘤病理分级及增值指数预测研究, 负责人, 地方任务, 2020-07--2023-06
（ 11 ） 多模态深度学习网络构建用于术前预测肝癌微血管侵犯, 负责人, 国家任务, 2020-01--2024-12

现指导学生

林佳沛  硕士研究生  081104-模式识别与智能系统