损伤修复机制，组织工程和器官再生，免疫治疗

   

071006-神经生物学
0710J6-再生医学
083100-生物医学工程

损伤修复机制;组织工程和器官再生;免疫治疗

2009-03--2009-08   美国加州大学戴维斯分校   访问学者
1999-04--2004-06   阿伯丁大学   博士
1997-01--1999-03   日本滨松医科大学   访问学者
1995-09--1998-08   中国医科大学眼科   硕士
1989-09--1995-08   中国医科大学   本科

1989/09-1995/06    中国中国医科大学   医疗系           本科（M.D.）

1995/09-1998/06    中国中国医科大学   眼科学           硕士（M.Sc.）

1999/09-2004/06    英国阿伯丁大学     生物医学科学     博士（Ph.D.）

07/2019-至今  中国科学院深圳先进技术研究院，研究员

08/2017-至今  英国卡迪夫大学口腔学院，副院长

10/2009-至今  英国卡迪夫大学口腔学院，再生医学终身教授

10/2009-至今  英国卡迪夫大学附属威尔士医院眼科，英国医师协会注册医师

10/2005-至今  英国皇家学会大学研究员（URF Fellow，the Royal Society）

10/2007-09/2009   英国阿伯丁大学生命科学和医学学院，副教授

03/2009-08/2009   美国加州大学戴维斯分校，访问学者

10/2005-10/2010   英国阿伯丁大学附属阿伯丁皇家医院，英国医师协会注册医师

12/2004-01/2005   美国约翰霍普金斯大学 Peter Devreotes实验室，访问学者

03/2003-06/2003   加拿大多伦多大学Josef Penninger实验室，访问学者

04/1999-09/2005   英国阿伯丁大学生命科学和医学学院，博士后。

01/1997-03/1999   日本滨松医科大学，访问学者

   

[1] 宋冰. 一种电信号通过调节皮肤DCs/LCs提呈至T细胞而调控集体免疫反应的方法. CN202010016434.6, 2020-01-08.
[2] 李建一, 宋冰, 殷涛, 刘志鹏, 李颖. 用于促进自体移植脂肪瓣再生的电刺激设备. 中国: CN108031002A, 2018-05-15.
[3] 于艳秋, 宋冰, 吕亚楠, 荣耀星, 邓雯雯, 时兆田, 张停停, 李秀文. 一种诱导牙髓间充质干细胞分化为神经细胞的方法. 中国: CN104726406B, 2018-05-01.

   

[1] Liu, Hong, Zhang, Zhancheng, Zhou, Shenli, Liu, Xianfang, Li, Guodong, Song, Bing, Xu, Wei. Claudin-1/4 as directly target gene of HIF-1 alpha can feedback regulating HIF-1 alpha by PI3K-AKT-mTOR and impact the proliferation of esophageal squamous cell though Rho GTPase and p-JNK pathway. CANCER GENE THERAPY[J]. 2022, 29(6): 665-682, http://dx.doi.org/10.1038/s41417-021-00328-2.
[2] Udduttula, Anjaneyulu, Li, Jian, Ma, Zhen, Teng, Bin, Zhang, Jian, V, Ferreira, Ana M, Gentile, Piergiorgio, Wang, Guocheng, Zhao, Xiaobing, Ren, PeiGen. A novel apatite-inspired Sr-5(PO4)(2)SiO4 plasma-sprayed coating on Ti alloy promoting biomineralization, osteogenesis and angiogenesis. CERAMICS INTERNATIONAL[J]. 2022, 48(8): 10979-10989, http://dx.doi.org/10.1016/j.ceramint.2021.12.317.
[3] Li, Yaling, Wu, Yutong, Gao, Yali, Niu, Xueli, Li, Jingyi, Tang, Mingsui, Fu, Chang, Qi, Ruiqun, Song, Bing, Chen, Hongduo, Gao, Xinghua, Yang, Ying, Guan, Xiuhao. Machine-learning based prediction of prognostic risk factors in patients with invasive candidiasis infection and bacterial bloodstream infection: a singled centered retrospective study. BMC INFECTIOUS DISEASES[J]. 2022, 22(1): https://doaj.org/article/323b287a31cf42b9826936dfca62f28b.
[4] YaLing Li, XueLi Niu, YaLi Gao, XiuHao Guan, Bing Song, JingYi Li, MingSui Tang. LncRNA BASP1‐AS1 interacts with YBX1 to regulate Notch transcription and drives the malignancy of melanoma. CANCER SCIENCE,112,11(2021-09-29). 2021, http://gooa.las.ac.cn/external/index?type=-1&pid=1788744.
[5] Bing Song, Yu Gu, Wenkai Jiang, Ying Li, Wayne Nishio Ayre, Zhipeng Liu, Tao Yin, Christopher Janetopoulos, Miho Iijima, Peter Devreotes, Min Zhao. Electric signals counterbalanced posterior vs anterior PTEN signaling in directed migration of Dictyostelium. CELL & BIOSCIENCE[J]. 2021, 11(1): 1-18, http://dx.doi.org/10.1186/s13578-021-00580-x.
[6] Song Bing. A 5-year review of invasive fungal infection at an academic medical centre. Frontiers in Cellular and Infection Microbiology. 2020, [7] Li, YaLing, Gao, YaLi, Niu, XueLi, Wu, YuTong, Du, YiMei, Tang, MingSui, Li, JingYi, Guan, XiuHao, Song, Bing. Identification of Subtype-Specific Metastasis-Related Genetic Signatures in Sarcoma. FRONTIERS IN ONCOLOGY[J]. 2020, 10: https://doaj.org/article/c35a85f695bc416a886df4e5a0a75b87.
[8] Yali Gao, Yaling Li, Xueli Niu, Yutong Wu, Xiuhao Guan, Yuxiao Hong, Hongduo Chen, Bing Song. Identification and Validation of Prognostically Relevant Gene Signature in Melanoma. BIOMED RESEARCH INTERNATIONAL[J]. 2020, 2020: https://doaj.org/article/a7b2c5c6accb4b7a8090bd333b4ee221.
[9] Cheng, WenXiang, Huang, Huan, Chen, JianHai, Zhang, TianTian, Zhu, GuoYuan, Zheng, ZhengTan, Lin, JieTao, Hu, YiPing, Zhang, Yong, Bai, XueLing, Wang, Yan, Xu, ZhanWang, Song, Bing, Mao, YiYing, Yang, Fei, Zhang, Peng. Genistein inhibits angiogenesis developed during rheumatoid arthritis through the IL-6/JAK2/STAT3/VEGF signalling pathway. JOURNAL OF ORTHOPAEDIC TRANSLATION[J]. 2020, 22: 92-100, http://dx.doi.org/10.1016/j.jot.2019.07.007.
[10] Yiping Hu, Tiantian Zhang, Jingqin Chen, WenXiang Cheng, Jianhai Chen, Zhengtan Zheng, Jietao Lin, Guoyuan Zhu, Yong Zhang, Xueling Bai, Yan Wang, Bing Song, Qingwen Wang, Ling Qin, Peng Zhang. Downregulation of Hypoxia-Inducible Factor-1α by RNA Interference Alleviates the Development of Collagen-Induced Arthritis in Rats. MOLECULAR THERAPY - NUCLEIC ACIDS[J]. 2020, 19: 1330-1342, [11] Liu, Peng, Kong, Lingming, Liang, Keke, Wu, Yunhao, Jin, Haoyi, Song, Bing, Tan, Xiaodong. Identification of dissociation factors in pancreatic Cancer using a mass spectrometry-based proteomic approach. BMC CANCER[J]. 2020, 20(1): http://dx.doi.org/10.1186/s12885-020-6522-3.
[12] Jiang, Wenkai, Wang, Diya, Alraies, Amr, Liu, Qian, Zhu, Bangfu, Sloan, Alastair J, Ni, Longxing, Song, Bing. Wnt-GSK3/-Catenin Regulates the Differentiation of Dental Pulp Stem Cells into Bladder Smooth Muscle Cells. STEM CELLS INTERNATIONAL[J]. 2019, 2019: https://doaj.org/article/2faf80471e174b06b2fef05955cfa38f.
[13] Song Bing. Potential immunomodulatory effects of SCAP on Treg conversion in tissue regeneration for regenerative endodontic treatment. International Endodontic Journal. 2019, [14] Qiao, Shupei, Liu, Yi, Han, Fengtong, Guo, Mian, Hou, Xiaolu, Ye, Kangruo, Deng, Shuai, Shen, Yijun, Zhao, Yufang, Wei, Haiying, Song, Bing, Yao, Lifen, Tian, Weiming. An Intelligent Neural Stem Cell Delivery System for Neurodegenerative Diseases Treatment. ADVANCED HEALTHCARE MATERIALS[J]. 2018, 7(12): https://www.webofscience.com/wos/woscc/full-record/WOS:000435764200007.
[15] Song Bing. Microfluidic Encapsulation Supports TStem Ce11 Viability, Proliferation, and Neuronal Differentiation. Tissue Eng Part C. 2018, [16] Zhang, Gaofeng, Edmundson, Mathew, Telezhkin, Vsevolod, Gu, Yu, Wei, Xiaoqing, Kemp, Paul J, Song, Bing. The Role of Kv1.2 Channel in Electrotaxis Cell Migration. JOURNAL OF CELLULAR PHYSIOLOGY[J]. 2016, 231(6): 1375-1384, https://www.webofscience.com/wos/woscc/full-record/WOS:000370736600020.
[17] Song Bing. Heat increased the editing efficiency of human papillomavirus E2 gene by inducing upregulation of APOBEC3A and 3G.. JInvest Dermatol.. 2016, [18] Xiaoqing Wei, AlastairSloan, Julia Oni, Longxing Ni, Amr Alraies, Meena Agarwal, Vijay Gudla, Bing Song, Wenkai Jiang, Qian Liu. Bladder Smooth Muscle Cells Differentiation from Dental Pulp Stem Cells: Future Potential for Bladder Tissue Engineering. HINDAWI PUBLISHING CORPORATION. 2016, http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201902223684147ZK.
[19] Song Bing. Inhibition of HSP90 Promotes Neural Stem Cel1 Survival from Oxidative Stress through Attenuating NF-KB/p65 Activation.. Oxidative Medicine and Cellular Longevity. 2016, [20] Ng, Wai Siene, Binley, Katie, Song, Bing, Morgan, James E. Use of magnetic nanoparticles and oscillating magnetic field for non-viral gene transfer into mouse cornea. LANCETnull. 2015, 385: 75-75, https://www.webofscience.com/wos/woscc/full-record/WOS:000360570500075.
[21] Haan, Niels, Zhu, Bangfu, Wang, Jian, Wei, Xiaoqing, Song, Bing. Crosstalk between macrophages and astrocytes affects proliferation, reactive phenotype and inflammatory response, suggesting a role during reactive gliosis following spinal cord injury. JOURNAL OF NEUROINFLAMMATION[J]. 2015, 12(1): http://dx.doi.org/10.1186/s12974-015-0327-3.
[22] Mehrban N. Functionalized a-Helical Peptide Hydrogels for Neural Tissue Engineering.. 2015, http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201804200006561LZ.
[23] Song Bing. Polarized macrophages have distinct effects on embryonic spinal-cord-derived neural stem cells after grafting to injured sites of spinal cord. Mol Ther.. 2015, [24] Zhang Gaofeng, Gu Yu, Begum Rumena, Chen Hongduo, Gao Xinghua, McGrath John A., Parsons Maddy, Song Bing. Kindlin-1 Regulates Keratinocyte Electrotaxis. THE JOURNAL OF INVESTIGATIVE DERMATOLOGY. 136(11): 2229-2239, http://dx.doi.org/10.1016/j.jid.2016.05.129.

   

（ 1 ） 国家“****”创新人才长期项目, 主持, 国家级, 2019-09--2024-08

（1）Can Stem Cells Sense and Respond to Electric Signals During Tissue Repair?   2018-05-09
（2）Electrical stimulation regulated neural regeneration & repair   2016-06-16
（3）Neuronal and smooth muscle differentiation from dental pulp stem cells   2016-06-11
（4）co-chair   2015-05-22