发表论文
[1] Biomolecules. 2024, 通讯作者 [2] nt. J. Mol. Sci.. 2023, 通讯作者 [3] Stem Cells. 2022, 通讯作者 [4] Oxidative Medicine and Cellular Longevity. 2022, 通讯作者 [5] Cell Proliferation. 2022, 通讯作者 [6] Int. J. Mol. Sci.. 2022, 通讯作者 [7] Signal Transduction and Targeted Therapy. 2022, 通讯作者 [8] Frontiers in Cellular Neuroscience. 2022, 通讯作者 [9] Wang, Qinying, Dong, Xiaoxu, Hu, Tingting, Qu, Chao, Lu, Jing, Zhou, Yue, Li, Jinsong, Pei, Gang. Constitutive Activity of Serotonin Receptor 6 Regulates Human Cerebral Organoids Formation and Depression-like Behaviors. STEM CELL REPORTS[J]. 2021, 第 8 作者 通讯作者 16(1): 75-88, http://dx.doi.org/10.1016/j.stemcr.2020.11.015.[10] Yi Li, Jing Lu, Xin Cao, Hongwei Zhao, Longfei Gao, Peng Xia, Gang Pei. A Newly Synthesized Rhamnoside Derivative Alleviates Alzheimer’s Amyloid-β-Induced Oxidative Stress, Mitochondrial Dysfunction, and Cell Senescence through Upregulating SIRT3. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY[J]. 2020, 第 7 作者2020: [11] Zhou, Yue, Duan, Yanhong, Huang, Shichao, Zhou, Xuan, Zhou, Lishuang, Hu, Tingting, Yang, Yongfeng, Lu, Jing, Ding, Kan, Guo, Dean, Cao, Xiaohua, Pei, Gang. Polysaccharides from Lycium barbarum ameliorate amyloid pathology and cognitive functions in APP/PS1 transgenic mice. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2020, 第 12 作者 通讯作者 144: 1004-1012, http://dx.doi.org/10.1016/j.ijbiomac.2019.09.177.[12] Pei Gang. Correction for: A novel rhamnoside derivative PL402 up-regulates matrix metalloproteinase 3/9 to promote Aβ degradation and alleviates Alzheimer’s-like pathology. Aging. 2020, 第 1 作者 通讯作者 [13] Wang, Qinying, Dong, Xiaoxu, Lu, Jing, Hu, Tingting, Pei, Gang. Constitutive activity of a G protein-coupled receptor, DRD1, contributes to human cerebral organoid formation. STEM CELLS[J]. 2020, 第 5 作者 通讯作者 38(5): 653-665, http://dx.doi.org/10.1002/stem.3156.[14] An, Yuqian, Zhang, Hong, Huang, Shichao, Pei, Gang. PL201, a Reported Rhamnoside Against Alzheimer's Disease Pathology, Alleviates Neuroinflammation and Stimulates Nrf2 Signaling. FRONTIERS IN IMMUNOLOGY[J]. 2020, 第 4 作者 通讯作者 11: https://doaj.org/article/cf14383ebb234478bc1ea395e2d3fb96.[15] Gao, Longfei, Zhang, Zhen, Lu, Jing, Pei, Gang. Mitochondria Are Dynamically Transferring Between Human Neural Cells and Alexander Disease-Associated GFAP Mutations Impair the Astrocytic Transfer. FRONTIERS IN CELLULAR NEUROSCIENCE[J]. 2019, 第 4 作者 通讯作者 13: https://doaj.org/article/30d0ea6ce48d4a5783af38421ec91d5a.[16] Pei Gang. An analog derived from phenylpropanoids ameliorates Alzheimer’s diseaseelike pathology and protects mitochondrial function. Neurobiology of Aging. 2019, 第 1 作者 通讯作者 [17] Gao, Longfei, Huang, Shichao, Zhang, Hong, Hua, Wei, Xin, Shunmei, Cheng, Lin, Guan, Wuqiang, Yu, Yongchun, Mao, Ying, Pei, Gang. Suppression of glioblastoma by a drug cocktail reprogramming tumor cells into neuronal like cells. SCIENTIFIC REPORTS[J]. 2019, 第 10 作者 通讯作者 9(1): https://doaj.org/article/486d1e106e8541d3a7870790ae3e1646.[18] Xin Wang, Gang Pei. Visualization of Alzheimer’s Disease Related α-/β-/γ-Secretase Ternary Complex by Bimolecular Fluorescence Complementation Based Fluorescence Resonance Energy Transfer. FRONTIERS IN MOLECULAR NEUROSCIENCE[J]. 2018, 第 2 作者11: https://doaj.org/article/62596de022a544af8494577e14345c68.[19] Wang, Xin, Wang, Congcong, Pei, Gang. α-secretase ADAM10 physically interacts with β-secretase BACE1 in neurons and regulates CHL1 proteolysis. JOURNAL OF MOLECULAR CELL BIOLOGY[J]. 2018, 第 3 作者 通讯作者 10(5): 411-422, http://dx.doi.org/10.1093/jmcb/mjy001.[20] Yang, Wenjuan, Zhou, Keyan, Zhou, Yue, An, Yuqian, Hu, Tingting, Lu, Jing, Huang, Shichao, Pei, Gang. Naringin Dihydrochalcone Ameliorates Cognitive Deficits and Neuropathology in APP/PS1 Transgenic Mice. FRONTIERS IN AGING NEUROSCIENCE[J]. 2018, 第 8 作者 通讯作者 10: https://doaj.org/article/458504f1bac7439dbccdd740958d36f5.[21] Pei Gang. NF-kB directly regulates b-arrestin-1 expression and forms a negative feedback circuit in TNF-a–induced cell death. The FASEB Journal. 2018, 第 1 作者 通讯作者 [22] Jing Lu, Xiaohang Li, Qinying Wang, Gang Pei. Dopamine D2 receptor and β-arrestin 2 mediate Amyloid-β elevation induced by anti-parkinson's disease drugs, levodopa and piribedil, in neuronal cells.. PLOSONE[J]. 2017, 第 4 作者12(3): https://doaj.org/article/f3911f37ff0f4a848d47f658b9e6b0ab.[23] Huang, Shichao, Mao, Jianxin, Ding, Kan, Zhou, Yue, Zeng, Xianglu, Yang, Wenjuan, Wang, Peipei, Zhao, Cun, Yao, Jian, Xia, Peng, Pei, Gang. Polysaccharides from Ganoderma lucidum Promote Cognitive Function and Neural Progenitor Proliferation in Mouse Model of Alzheimer's Disease. STEM CELL REPORTS[J]. 2017, 第 11 作者 通讯作者 8(1): 84-94, http://dx.doi.org/10.1016/j.stemcr.2016.12.007.[24] Gao, Longfei, Guan, Wuqiang, Wang, Min, Wang, Huihan, Yu, Jiali, Liu, Qing, Qiu, Binlong, Yu, Yongchun, Ping, Yifang, Bian, Xiuwu, Shen, Li, Pei, Gang. Direct Generation of Human Neuronal Cells from Adult Astrocytes by Small Molecules. STEM CELL REPORTS[J]. 2017, 第 12 作者 通讯作者 8(3): 538-547, https://doaj.org/article/33929677d0d249d7a0a939129f32301e.[25] Cai, Qing, Li, Yuanyuan, Pei, Gang. Polysaccharides from Ganoderma lucidum attenuate microglia-mediated neuroinflammation and modulate microglial phagocytosis and behavioural response. JOURNAL OF NEUROINFLAMMATION[J]. 2017, 第 3 作者 通讯作者 14(1): http://dx.doi.org/10.1186/s12974-017-0839-0.[26] Guo, Ao, Huang, Shichao, Yu, Jiali, Wang, Huihan, Li, Haisen, Pei, Gang, Shen, Li. Single-Cell Dynamic Analysis of Mitosis in Haploid Embryonic Stem Cells Shows the Prolonged Metaphase and Its Association with Self-diploidization. STEM CELL REPORTS[J]. 2017, 第 6 作者 通讯作者 8(5): 1124-1134, https://doaj.org/article/7e9202fe3b264851ace70ff8940ace3d.[27] Li, Xiaohang, Wang, Qinying, Hu, Tingting, Wang, Ying, Zhao, Jian, Lu, Jing, Pei, Gang. A tricyclic antidepressant, amoxapine, reduces amyloid- ß generation through multiple serotonin receptor 6-mediated targets. SCIENTIFIC REPORTS[J]. 2017, 第 7 作者 通讯作者 7(1): http://dx.doi.org/10.1038/s41598-017-04144-3.[28] Congcong Wang, Xianglu Zeng, Zhaocai Zhou, Jian Zhao, Gang Pei. β-arrestin-1 contributes to brown fat function and directly interacts with PPARα and PPARγ. SCIENTIFIC REPORTS. 2016, 第 5 作者6: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908412/.[29] Xiaohang Li, Jin Cui, Yang Yu, Wei Li, Yujun Hou, Xin Wang, Dapeng Qin, Cun Zhao, Xinsheng Yao, Jian Zhao, Gang Pei. Traditional Chinese Nootropic Medicine Radix Polygalae and Its Active Constituent Onjisaponin B Reduce β-Amyloid Production and Improve Cognitive Impairments.. PLOS ONE[J]. 2016, 第 11 作者11(3): https://doaj.org/article/9f58d7c4a527488080f9447dac9ed2a7.[30] Jing Lu, Jin Cui, Xiaohang Li, Xin Wang, Yue Zhou, Wenjuan Yang, Ming Chen, Jian Zhao, Gang Pei. An Anti-Parkinson's Disease Drug via Targeting Adenosine A2A Receptor Enhances Amyloid-β Generation and γ-Secretase Activity.. PLOS ONE[J]. 2016, 第 9 作者11(11): https://doaj.org/article/48132f9baa3f4822b81c1fba09bb0da0.[31] Cai, Qing, Li, Yuanyuan, Mao, Jianxin, Pei, Gang. Neurogenesis-Promoting Natural Product α-Asarone Modulates Morphological Dynamics of Activated Microglia. FRONTIERS IN CELLULAR NEUROSCIENCE[J]. 2016, 第 4 作者 通讯作者 10: http://dx.doi.org/10.3389/fncel.2016.00280.[32] Hu, Wenxiang, Qiu, Binlong, Guan, Wuqiang, Wang, Qinying, Wang, Min, Li, Wei, Gao, Longfei, Shen, Lu, Huang, Yin, Xie, Gangcai, Zhao, Hanzhi, Jin, Ying, Tang, Beisha, Yu, Yongchun, Zhao, Jian, Pei, Gang. Direct Conversion of Normal and Alzheimer's Disease Human Fibroblasts into Neuronal Cells by Small Molecules. CELL STEM CELL[J]. 2015, 第 16 作者17(2): 204-212, http://dx.doi.org/10.1016/j.stem.2015.07.006.[33] Cheng, Lin, Gao, Longfei, Guan, Wuqiang, Mao, Jianxin, Hu, Wenxiang, Qiu, Binlong, Zhao, Jian, Yu, Yongchun, Pei, Gang. Direct conversion of astrocytes into neuronal cells by drug cocktail. CELL RESEARCH. 2015, 第 9 作者 通讯作者 25(11): 1269-1272, https://www.webofscience.com/wos/woscc/full-record/WOS:000365049100012.[34] Pei Gang. γ- Secretase modulators and inhibitors induce different conformational changes of presenilin 1 revealed by FLIM and FRET.. J Alzheimers Dis. 2015, 第 1 作者 通讯作者 [35] Mao, Jianxin, Huang, Shichao, Liu, Shangfeng, Feng, XiaoLin, Yu, Miao, Liu, Junjun, Sun, Yi Eve, Chen, Guoliang, Yu, Yang, Zhao, Jian, Pei, Gang. A herbal medicine for Alzheimer's disease and its active constituents promote neural progenitor proliferation. AGING CELL[J]. 2015, 第 11 作者 通讯作者 14(5): 784-796, https://www.doi.org/10.1111/acel.12356.[36] 裴钢. Generation of Neural Progenitor Cells by Chemical Cocktails and Hypoxia. CELL RES. 2014, 第 1 作者24(6): 665-679, [37] Hou, Yujun, Wang, Ying, Zhao, Jian, Li, Xiaohang, Cui, Jin, Ding, Jianqing, Wang, Ying, Zeng, Xianglu, Ling, Yun, Shen, Xiaoheng, Chen, Shengdi, Huang, Chenggang, Pei, Gang. Smart Soup, a Traditional Chinese Medicine Formula, Ameliorates Amyloid Pathology and Related Cognitive Deficits. PLOS ONE[J]. 2014, 第 13 作者9(11): https://doaj.org/article/0708c7a1da344fce8f3ef59526839164.[38] 裴钢. Beta-arrestin1 regulates γ-secretase complex assembly and modulates amyloid-β pathology. CELL RES. 2013, 第 1 作者23(3): 351-365, [39] Pei Gang. Deficiency of b-arrestin1 ameliorates collagen-induced arthritis with impaired TH17 cell differentiation.. PNAS. 2013, 第 1 作者 通讯作者 [40] Hu, Wenxiang, Zhao, Jian, Pei, Gang. Activation of Aryl Hydrocarbon Receptor (AhR) by Tranilast, an Anti-allergy Drug, Promotes miR-302 Expression and Cell Reprogramming. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2013, 第 3 作者 通讯作者 288(32): 22972-22984, http://dx.doi.org/10.1074/jbc.M113.475624.[41] Yue, Rui, Li, Haisen, Liu, Huan, Li, Yuanyuan, Wei, Bin, Gao, Ge, Jin, Yi, Liu, Tingxi, Wei, Liping, Du, Jiulin, Pei, Gang. Thrombin Receptor Regulates Hematopoiesis and Endothelial-to-Hematopoietic Transition. DEVELOPMENTAL CELL[J]. 2012, 第 11 作者 通讯作者 22(5): 1092-1100, http://dx.doi.org/10.1016/j.devcel.2012.01.025.[42] 裴钢. {beta}arrestin1 represses adipogenesis and inflammatary responses through its interaction with PPAR{gamma}. J BIOL CHEM. 2011, 第 1 作者286: 28403-28413, [43] Pei Gang. βarrestin1 represses diet-induced obesity. J Biol Chem. 2011, 第 1 作者 通讯作者 [44] Chen, Taotao, Shen, Li, Yu, Jie, Wan, Hongjiang, Guo, Ao, Chen, Jiekai, Long, Yuan, Zhao, Jian, Pei, Gang. Rapamycin and other longevity-promoting compounds enhance the generation of mouse induced pluripotent stem cells. AGING CELL[J]. 2011, 第 9 作者 通讯作者 10(5): 908-911, https://www.doi.org/10.1111/j.1474-9726.2011.00722.x.[45] Shen, Li, Gao, Ge, Zhang, Ying, Zhang, He, Ye, Zhiqiang, Huang, Shichao, Huang, Jinyan, Kang, Jiuhong. A single amino acid substitution confers enhanced methylation activity of mammalian Dnmt3b on chromatin DNA. NUCLEIC ACIDS RESEARCH[J]. 2010, 38(18): 6054-6064, http://dx.doi.org/10.1093/nar/gkq456.[46] Chen, Taotao, Yuan, Detian, Wei, Bin, Jiang, Jing, Kang, Jiuhong, Ling, Kun, Gu, Yijun, Li, Jinsong, Xiao, Lei, Pei, Gang. E-Cadherin-Mediated Cell-Cell Contact Is Critical for Induced Pluripotent Stem Cell Generation. STEM CELLS[J]. 2010, 第 10 作者 通讯作者 28(8): 1315-1325, https://www.doi.org/10.1002/stem.456.[47] Teng, Lin, Zhao, Jian, Wang, Feifei, Ma, Lan, Pei, Gang. A GPCR/secretase complex regulates β- and γ-secretase specificity for Aβ production and contributes to AD pathogenesis. CELL RESEARCH[J]. 2010, 第 5 作者 通讯作者 20(2): 138-153, http://dx.doi.org/10.1038/cr.2010.3.[48] 裴钢. β-Arrestin1 regulates zebrafish hematopoiesis through binding to YY1 and relieving polycomb group repression. CELL. 2009, 第 1 作者139(3): 535-546, http://dx.doi.org/10.1016/j.cell.2009.08.038.[49] 裴钢. MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis. NAT IMMUNOL. 2009, 第 1 作者10: 1252 –1259, [50] 裴钢. Deficiency of a barrestin2 signal complex contributes to insulin resistance. NATURE. 2009, 第 1 作者457: 1146-1149, [51] Li Haisen, Yue Rui, Wei Bin, Gao Ge, Du Jiulin, Pei Gang. Lysophosphatidic acid acts as a nutrient-derived developmental cue to regulate early hematopoiesis. THE EMBO JOURNAL. 第 6 作者33(12): 1383-1396, http://www.irgrid.ac.cn/handle/1471x/850734.[52] Wei Bin, Pei Gang. microRNAs: critical regulators in Th17 cells and players in diseases. CELLULAR AND MOLECULAR IMMUNOLOGY[J]. 第 2 作者7(3): 175-181, https://www.webofscience.com/wos/woscc/full-record/WOS:000277282200003.