裴为华-中国科学院大学-UCAS

基本信息

裴为华男博导中国科学院半导体研究所
电子邮件： peiwh@semi.ac.cn
通信地址：北京市清华东路甲35号
邮政编码：

研究领域

研究方向主要为神经接口和脑机交互，研究用于记录或干预神经活动的器件和相关技术。通过微纳加工和表面功能修饰，研究电极与组织界面特性与提取信号信噪比之间的对应关系。在此基础上，研制高通量、高性能的植入式神经微电极传感阵列器件；研究满足在体环境下使用的便捷式脑电传感材料、器件和对应的安放及信号读出系统。探索和开发新的神经信号感知和干预方法及相关技术。在国内外发表相关论文50 余篇，授权发明专利11 项。

招生信息

神经接口技术属于交叉学科，研究内容涉及材料科学、电化学技术、电子科学与技术、微纳加工等多学科。欢迎有相关专业背景的青年才俊加入！

招生专业

080903-微电子学与固体电子学
083100-生物医学工程
085208-电子与通信工程

招生方向

神经接口器件及应用
便携式生理传感器

教育背景

2007-11--2012-12 中国科学院半导体研究所副研究员
2002-09--2005-05 中国科学院半导体研究所博士

工作经历

工作简历

2013-01~现在, 中国科学院半导体研究所, 研究员
2005-06~2007-11,中国科学院导体研究所, 助理研究员

教授课程

硅微机械传感器
光电子与微电子集成
硅微机械加工
生物芯片技术前沿

专利与奖励

奖励信息

（1）便携式人体生理信号检测系统研发及应该, 二等奖, 省级, 2012

专利成果

[1] 裴为华, 吴晓婷, 王阳. 一种兼顾电生理信号记录的微型荧光成像系统. CN: CN113456089A, 2021-10-01.
[2] 裴为华, 李亚民, 王阳, 陈茹茹. 一种无线闭环控制系统及方法. CN: CN113082536A, 2021-07-09.
[3] 裴为华, 王阳, 邢立化, 魏春蓉. 柔性电极导入装置. CN: CN112999511A, 2021-06-22.
[4] 裴为华, 刘智多, 陈弘达. 基于角膜接触镜的光学眼压检测设备及制备、使用方法. CN: CN111407227B, 2021-06-18.
[5] 王毅军, 田森, 裴为华, 张熙, 陈弘达. 可穿戴脑电疲劳监测系统. CN: CN112515680A, 2021-03-19.
[6] 裴为华, 魏春蓉. U型柔性电极植入系统及其制备方法. CN: CN112386262A, 2021-02-23.
[7] 裴为华, 李亚民, 王阳, 吴晓婷. 多光源钙离子荧光检测方法及系统. CN: CN112089401A, 2020-12-18.
[8] 裴为华, 魏春蓉. 多维度提取神经元信号的柔性神经电极植入系统. CN: CN112022154A, 2020-12-04.
[9] 裴为华, 窦智强, 刘智多, 王阳. 基于微流体技术的变电容式眼压传感器及其系统. CN: CN112022088A, 2020-12-04.
[10] 裴为华, 查爱华, 吴晓婷, 王毅军, 田森. 入发式脑电帽. CN: CN212066710U, 2020-12-04.
[11] 裴为华, 魏春蓉. 柔性电极植入系统. CN: CN111990995A, 2020-11-27.
[12] 裴为华, 吴晓婷, 邢潇. 一种脑电电极头戴. CN: CN111887842A, 2020-11-06.
[13] 裴为华, 刘智多, 陈弘达. 基于角膜接触镜光栅的穿戴式眼压检测装置和检测方法. CN: CN111345777A, 2020-06-30.
[14] 裴为华, 查爱华, 吴晓婷, 王毅军, 田森. 保持接触部位长效润湿的电极及设备. CN: CN111281381A, 2020-06-16.
[15] 王思凯, 刘鸣, 张旭, 裴为华, 陈弘达. 基于加速度计和陀螺仪的人体呼吸情况采集贴及制备方法. CN: CN111248922A, 2020-06-09.
[16] 徐淮良, 裴为华, 苏越, 王飞, 詹学鹏, 张雪莲, 张旭, 陈弘达. 一种解码大脑活动的针状高密度电极阵列的制备方法. CN: CN109962013A, 2019-07-02.
[17] 裴为华, 王飞, 刘智多, 邢潇, 陈弘达. 能抑制光噪声的微电极、采用其的电路及其制备方法. CN: CN109911839A, 2019-06-21.
[18] 裴为华, 徐淮良, 苏越, 杨晓伟. 神经光电极及其制备方法. CN: CN109820481A, 2019-05-31.
[19] 裴为华, 徐淮良, 苏越, 吴晓婷. 神经元活动检测方法及探测系统. CN: CN109793502A, 2019-05-24.
[20] 耿照新, 苏玥, 吕晓庆, 裴为华, 陈弘达. 自吸纳米压印制备金属纳米结构的方法. CN: CN109609907A, 2019-04-12.
[21] 吕晓庆, 耿照新, 裴为华, 陈弘达. 基于LSPR的多通道微流控传感芯片及其制作方法. CN: CN108380249A, 2018-08-10.
[22] 裴为华, 邢潇, 孙雪梅, 刘智多, 陈弘达. 取向碳纳米管自粘附干电极及其制备工艺. CN: CN108294747A, 2018-07-20.
[23] 裴为华, 解宇星, 邢潇, 陈弘达. 基于光纤的多记录点透明光电极. CN: CN106291813A, 2017-01-04.
[24] 裴为华, 张贺, 郭旭宏, 陈弘达. 可用于动态心电测量的柔性心电电极及制作方法. CN: CN105615874A, 2016-06-01.
[25] 裴为华, 邢潇, 郭旭宏, 陈弘达. 一种集中供湿的脑电帽及柔性微渗电极结构. CN: CN105411584A, 2016-03-23.
[26] 裴为华, 陈远方, 郭旭宏, 陈弘达. 用于脑电信号记录的韧性爪式干电极及制备方法. CN: CN104799853A, 2015-07-29.
[27] 裴为华, 国冬梅, 陈远方, 张贺, 陈弘达. 增强聚对二甲苯薄膜与金属层粘附性的方法. CN: CN104404475A, 2015-03-11.
[28] 裴为华, 陈远方, 归强, 陈弘达. 基于有机晶体管的植入式柔性传感器及制备方法. CN: CN104330440A, 2015-02-04.
[29] 胡晓晖, 张旭, 刘鸣, 裴为华, 陈弘达. 一种多感官集成的电子皮肤及其制造方法. CN: CN104251751A, 2014-12-31.
[30] 裴为华, 张贺, 王宇, 陈远方, 陈弘达. 在柔性衬底表面制作硬质微针阵列的方法. CN: CN104140075A, 2014-11-12.
[31] 裴为华, 赵珊珊, 归强, 陈弘达. 一种用于组装神经元微电极阵列的电极排针. CN: CN103768709A, 2014-05-07.
[32] 张旭, 韩建强, 刘鸣, 裴为华, 陈弘达. 一种硅神经电极混合集成器件的制造方法. CN: CN103750833A, 2014-04-30.
[33] 裴为华, 归强, 陈三元, 陈远方, 陈弘达. 制备MSM结构CZT探测器的方法. CN: CN103165757A, 2013-06-19.
[34] 裴为华, 陈三元, 归强, 陈弘达. 纳米刻蚀印章及利用其进行纳米刻蚀的方法. CN: CN103145092A, 2013-06-12.
[35] 裴为华, 陈三元, 归强, 陈弘达. 制备硅基微电极的方法. CN: CN103101878A, 2013-05-15.
[36] 裴为华, 陈远方, 陈南晖, 归强, 陈弘达. 用于视网膜修复或功能的全透明柔性电极. CN: CN102988132A, 2013-03-27.
[37] 裴为华, 陈远方, 归强, 陈弘达. 制作基于微针阵列皮肤干电极的方法. CN: CN102988039A, 2013-03-27.
[38] 裴为华, 陈三元, 归强, 李雷, 陈弘达. 用于神经元刺激及电信号记录的光电极阵列及制备方法. CN: CN102830138A, 2012-12-19.
[39] 汤戎昱, 裴为华, 归强, 李雷, 陈弘达. 微电极阵列传感器. CN: CN202522538U, 2012-11-07.
[40] 裴为华, 赵辉, 王宇, 陈三元, 汤戎昱, 陈远方, 陈弘达. 制作立体神经微电极的方法. CN: CN102512151A, 2012-06-27.
[41] 裴为华, 王宇, 陈弘达. 柔性皮肤表面干电极及制备方法. CN: CN102499667A, 2012-06-20.
[42] 汤戎昱, 裴为华",null,null,"陈弘达. 微电极阵列传感器. CN: CN102495121A, 2012-06-13.
[43] 王娟, 裴为华, 郭凯, 陈弘达. 阵列化图形细胞的电调控方法. CN: CN102286646A, 2011-12-21.
[44] 陈弘达, 张旭, 裴为华, 黄北举. 采用T型电容网络反馈结构的CMOS生理信号放大器. CN: CN102158178A, 2011-08-17.
[45] 陈弘达, 李晓倩, 裴为华, 郭凯, 王宇. 用于记录神经活动电信号的柔性探针电极及其植入工具. CN: CN101884530A, 2010-11-17.
[46] 裴为华, 王宇, 郭凯, 归强, 王淑静, 朱琳, 陈弘达. 用于皮下药物注射的基于柔性基底的微针阵列及其制法. CN: CN101879336A, 2010-11-10.
[47] 陈弘达, 朱琳, 陈雄斌, 裴为华, 刘博, 杨宇, 董赞, 关宁. 一种利用半导体照明进行通信的系统及方法. CN: CN101867412A, 2010-10-20.
[48] 李艳, 杨富华, 裴为华. 以光刻胶为掩膜对二氧化硅进行深刻蚀的方法. CN: CN101852893A, 2010-10-06.
[49] 陈弘达, 朱琳, 裴为华, 张旭. 使用硅阵列孔装配微丝电极阵列的方法. CN: CN101543406B, 2010-09-15.
[50] 裴为华, 王宇, 郭凯, 陈弘达. 长期记录生理电信号的侵入式斜针无痛皮肤干电极器件. CN: CN101716073A, 2010-06-02.
[51] 裴为华, 陈海峰, 崔世钢, 张若昕, 陈弘达. 一种制作皮肤干电极的方法. CN: CN101322645A, 2008-12-17.
[52] 裴为华, 陈弘达, 朱琳, 张旭, 郭凯, 王淑静, 陈海峰. 带位置稳定结构的针状神经微电极. CN: CN201135436Y, 2008-10-22.
[53] 陈弘达, 张若昕, 裴为华, 隋小红. 硅V形槽板及利用硅V形槽板装配微丝电极阵列的方法. CN: CN101112309A, 2008-01-30.
[54] 陈弘达, 裴为华, 毛陆虹, 吴荣汉, 杜云, 唐君, 邓晖, 梁琨. 大规模光电集成RCE探测器面阵器件. CN: CN100349299C, 2007-11-14.
[55] 陈弘达, 吴荣汉, 杜云, 毛陆虹, 唐君, 裴为华, 梁琨. 基于激子效应的多量子阱光调制器/探测器列阵. CN: CN1319175C, 2007-05-30.
[56] 陈弘达, 隋晓红, 裴为华. CMOS电路与MEMS微电极的单片集成化方法. CN: CN1915797A, 2007-02-21.
[57] 陈弘达, 裴为华. 半导体薄片材料的横向研磨方法. CN: CN1815695A, 2006-08-09.
[58] 陈弘达, 申荣铉, 毛陆虹, 唐君, 裴为华, 高鹏. 应用自聚焦透镜阵列的并行光发射模块及制作方法. CN: CN1665086A, 2005-09-07.
[59] 陈弘达, 裴为华, 唐君, 申荣铉, 孙增辉, 贾九春. 利用光掩模板作无源对准的方法. CN: CN1661476A, 2005-08-31.
[60] 陈弘达, 申荣铉, 毛陆虹, 唐君, 裴为华, 高鹏, 崔增文. 垂直腔面发射激光器列阵的并行光发射模块及制作方法. 中国: CN1530681, 2004-09-22.

出版信息

发表论文

[1] 杨鑫泽, 裴为华, 刘媛媛. Chemical polymerization of conducting polymer poly(3,4-ethylenedioxythiophene) onto neural microelectrodes. Sensors and Actuators A: Physical[J]. 2023, 9: [2] Wang, Yang, Wang, Qifan, Zheng, Ruichen, Xu, Xinxiu, Yang, Xinze, Gui, Qiang, Yang, Xiaowei, Wang, Yijun, Cui, He, Pei, Weihua. Flexible multichannel electrodes for acute recording in nonhuman primates. MICROSYSTEMS & NANOENGINEERING[J]. 2023, 9(1): http://dx.doi.org/10.1038/s41378-023-00550-y.
[3] Yang Wang, Xinze Yang, Xiwen Zhang, Yijun Wang, Weihua Pei. Implantable intracortical microelectrodes: reviewing the present with a focus on the future. 微系统与纳米工程(英文)[J]. 2023, 9(1): 37-53, http://lib.cqvip.com/Qikan/Article/Detail?id=7109694041.
[4] Miao Yuan, Zhiduo Liu, Xiaoting Wu, Haoyang Gou, Yugui Zhang, Xin Ning, Weijun Li, Zhaohui Yao, Yijun Wang, Weihua Pei, Hongda Chen. High-sensitive microfluidic contact lens sensor for intraocular pressure visualized monitoring. SENSORS AND ACTUATORS: A. PHYSICAL[J]. 2023, 354: http://dx.doi.org/10.1016/j.sna.2023.114250.
[5] Zhang, Hengjie, Jiang, Biyi, Cheng, Chuantong, Huang, Beiju, Zhang, Huan, Chen, Run, Xu, Jiayi, Huang, Yulong, Chen, Hongda, Pei, Weihua, Chai, Yang, Zhou, Feichi. A Self-Rectifying Synaptic Memristor Array with Ultrahigh Weight Potentiation Linearity for a Self-Organizing-Map Neural Network. NANO LETTERS[J]. 2023, 23(8): 3107-3115, http://dx.doi.org/10.1021/acs.nanolett.2c03624.
[6] Qin, Fangbo, Xu, De, Zhang, Dapeng, Pei, Weihua, Han, Xinyong, Yu, Shan. Automated Hooking of Biomedical Microelectrode Guided by Intelligent Microscopic Vision. IEEE-ASME TRANSACTIONS ON MECHATRONICS. 2023, http://dx.doi.org/10.1109/TMECH.2023.3248112.
[7] Fang, Weihao, Lv, Xiaoqing, Ma, Zhengtai, Liu, Jian, Pei, Weihua, Geng, Zhaoxin. A Flexible Terahertz Metamaterial Biosensor for Cancer Cell Growth and Migration Detection. MICROMACHINES[J]. 2022, 13(4): http://dx.doi.org/10.3390/mi13040631.
[8] Fang, Weihao, Ma, Zhengtai, Lv, Xiaoqing, Liu, Jian, Pei, Weihua, Geng, Zhaoxin. Flexible terahertz metamaterial biosensor for label-free sensing of serum tumor marker modified on a non-metal area. OPTICS EXPRESS[J]. 2022, 30(10): 16630-16643, http://dx.doi.org/10.1364/OE.454647.
[9] Pei, Weihua, Wu, Xiaoting, Zhang, Xiang, Zha, Aihua, Tian, Sen, Wang, Yijun, Gao, Xiaorong. A Pre-Gelled EEG Electrode and Its Application in SSVEP-Based BCI. IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING[J]. 2022, 30: 843-850, http://dx.doi.org/10.1109/TNSRE.2022.3161989.
[10] Yamin Li, Shengwei Xu, Yang Wang, Yiming Duan, Qianli Jia, Jingyu Xie, Xiaowei Yang, Yiding Wang, Yuchuan Dai, Gucheng Yang, Miao Yuan, Xiaoting Wu, Yilin Song, Mixia Wang, Hongda Chen, Yijun Wang, Xinxia Cai, Weihua Pei. Wireless Closed-Loop Optical Regulation System for Seizure Detection and Suppression In Vivo. Frontiers in Nanotechnology[J]. 2022, 4: https://doaj.org/article/290a974142b042de9d40d58c04fa565b.
[11] Wei, Chunrong, Wang, Yang, Pei, Weihua, Han, Xinyong, Lin, Longnian, Liu, Zhiduo, Ming, Gege, Chen, Ruru, Wu, Pingping, Yang, Xiaowei, Zheng, Li, Wang, Yijun. Distributed implantation of a flexible microelectrode array for neural recording. MICROSYSTEMS & NANOENGINEERING[J]. 2022, 8(1): http://dx.doi.org/10.1038/s41378-022-00366-2.
[12] Su, Yue, Geng, Zhaoxin, Lv, Xiaoqing, Fang, Weihao, Wang, Shicai, Ma, Zhengtai, Pei, Weihua. Self-referenced plasmonic biosensor with gold grating on thin gold film. AIP ADVANCES[J]. 2021, 11(3): https://doaj.org/article/3991545985d64c258d5573a36b83b72e.
[13] Zhang, Hengjie, Cheng, Chuantong, Huang, Beiju, Zhang, Huan, Chen, Run, Huang, Yulong, Chen, Hongda, Pei, Weihua. Research on Pt/NiOx/WO3-x:Ti/W Multijunction Memristors with Synaptic Learning and Memory Functions. JOURNAL OF PHYSICAL CHEMISTRY LETTERS[J]. 2021, 12(14): 3600-3606, http://dx.doi.org/10.1021/acs.jpclett.1c00704.
[14] Liu, Zhiduo, Wang, Gang, Ye, Chen, Sun, Hongyan, Pei, Weihua, Wei, Chunrong, Dai, Wen, Dou, Zhiqiang, Sun, Qingyu, Lin, ChengTe, Wang, Yijun, Chen, Hongda, Shen, Guozhen. An Ultrasensitive Contact Lens Sensor Based On Self-Assembly Graphene For Continuous Intraocular Pressure Monitoring. ADVANCED FUNCTIONAL MATERIALS[J]. 2021, 31(29): http://dx.doi.org/10.1002/adfm.202010991.
[15] Su, Yue, Geng, Zhaoxin, Fang, Weihao, Lv, Xiaoqing, Wang, Shicai, Ma, Zhengtai, Pei, Weihua. Route to Cost-Effective Fabrication of Wafer-Scale Nanostructure through Self-Priming Nanoimprint. MICROMACHINES[J]. 2021, 12(2): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911382/.
[16] 吴晓婷, 裴为华, 王毅军, 陈弘达. 应用于脑机接口的便捷式头皮电极. 人工智能[J]. 2021, 16-25, http://lib.cqvip.com/Qikan/Article/Detail?id=7106431316.
[17] Dou, Zhiqiang, Tang, Jun, Liu, Zhiduo, Sun, Qigong, Wang, Yang, Li, Yamin, Yuan, Miao, Wu, Huijuan, Wang, Yijun, Pei, Weihua, Chen, Hongda. Wearable Contact Lens Sensor for Non-Invasive Continuous Monitoring of Intraocular Pressure. MICROMACHINES[J]. 2021, 12(2): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910926/.
[18] 荆彦锋, 李亚民, 杨晓伟, 裴为华. 应用于光遗传的双光通道32记录点植入式光电极. 半导体光电[J]. 2021, 42(4): 479-482, http://lib.cqvip.com/Qikan/Article/Detail?id=7105731385.
[19] Wu, Pingping, Wei, Chunrong, Yang, Wenjie, Lin, Longnian, Pei, Weihua, Wang, Jingxia, Jiang, Lei. Rewritable PEDOT Film Based on Water-Writing and Electroerasing. ACS APPLIED MATERIALS & INTERFACES[J]. 2021, 13(34): 41220-41230, http://dx.doi.org/10.1021/acsami.1c09531.
[20] Gang Cao, Chuantong Cheng, Hengjie Zhang, Huan Zhang, Run Chen, Beiju Huang, Xiaobing Yan, Weihua Pei, Hongda Chen. The application of halide perovskites in memristors. 半导体学报:英文版[J]. 2020, 41(5): 44-59, http://lib.cqvip.com/Qikan/Article/Detail?id=7101662438.
[21] 李亚民, 王阳, 陈弘达, 王毅军, 刘媛媛, 裴为华. 植入式光电极器件发展. 物理化学学报[J]. 2020, 36(12): 18-29, https://nxgp.cnki.net/kcms/detail?v=3uoqIhG8C46NmWw7YpEsKMypi3qVj28LEUDxQXHYyS3fbyEOrIfBzJaVMyFN_dY1uMof4rZ9y0FKOH_aeanMBB_exUrqoFQQ&uniplatform=NZKPT.
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发表著作

（1） electrode array for neural interface, Springer, 2017-12, 第 2 作者

科研活动

科研项目

（ 1 ）在体神经信号采集系统及集成技术研究, 主持, 国家级, 2011-01--2014-12
（ 2 ）光电极及其在神经电刺激与记录中的应用基础研究, 主持, 国家级, 2013-01--2015-12
（ 3 ）纳米修饰的植入电极材料及器件, 主持, 国家级, 2012-01--2014-12
（ 4 ）新型神经微电极阵列制备技术, 主持, 部委级, 2014-06--2016-12
（ 5 ）角膜接触镜式无线眼压监测系统关键技术研究, 主持, 国家级, 2017-01--2021-12
（ 6 ）在体神经信息微纳电极器件及集成技术基础研究, 参与, 国家级, 2011-01--2015-10
（ 7 ）用于神经接口的纳米光电传感机理及器件研究, 参与, 国家级, 2013-01--2017-12
（ 8 ）在体微纳光电器件与芯片集成技术及应用, 主持, 国家级, 2017-07--2022-06
（ 9 ）仿生假肢手感知与控制的神经信息解析和交互技术, 参与, 国家级, 2018-07--2022-12
（ 10 ）神经信号检测和调控新技术, 主持, 部委级, 2019-01--2019-12

参与会议

（1）THREE-DIMENSIONAL GRAPHENE AS SENSING ELEMENT FOR INTRAOCULAR PRESSURE MONITORING   Zhiduo Liu   2019-03-14
（2）Design of High-Density Electrodes for EEG Acquisition   2018-07-21
（3）Microelectrode,a key device for neuro interface   中德前言论坛   Weihua Pei   2013-05-23

合作情况

清华大学医学院神经工程实验室高小榕教授

清华大学生物医学工程系洪波教授

上海交通大学生物医学工程系蓝宁教授

华东师范大学脑功能基因组学研究所林龙年教授