LIU Ningning Principle investigator, Professor
Address：NO.1 West Beichen Road, Chaoyang District, Beijing 100101, China
E-mail：liunn@im.ac.cn or nnliu01@hotmail.com
Research Areas
1. Immune microenvironment regulatory mechanism of chronic infection to HCC.
2. Hepatic glucose and lipid metabolism during liver fibrosis, cirrhosis to hepatocellular carcinoma.
Education
2011-2014 Ph.D. Institute of Microbiology, University of Chinese Academy of Sciences
Experience
Work Experience
2022.11- Professor, Institute of Microbiology, CAS, China
2021-2022 Instructor, UT Southwestern Medical Center, USA
2017-2021 Postdoctoral Associate, University of Minnesota, USA
2014-2017 Assistant professor, Institute of Microbiology, Chinese Academy of Sciences, China
Publications
1. Ningning Liu, Clifford J. Steer, and Guisheng Song. MicroRNA-15a/16-1 Prevent Hepatocellular Carcinoma by Disrupting the Communication between Kupffer Cells and Regulatory T Cells. Gastroenterology, 2022. PMID: 34678217.
2. Ningning Liu, Xiaomei Wang, Clifford J. Steer, and Guisheng Song. MicroRNA-206 Promotes the Recruitment of CD8+ T Cells by Driving M1 Phase Polarization of Kupffer Cells. Gut, 2022. PMID: 34706869.
3. Ningning Liu, Clifford J Steer, Guisheng Song. MicroRNA-206 Enhances Antitumor Immunity by Disrupting the Communication between Malignant Hepatocytes and Tregs in c-Myc Mice. Hepatology, 2022. PMID: 34606648.
4. Ningning Liu*, Tianpeng Zhang*, Clifford J Steer, Guisheng Song. MicroRNA-378a-3p prevents initiation and growth of colorectal cancer by fine tuning polyamine synthesis. Cell & Bioscience, 2023. PMID: 36457036. *co-first author.
5. Ningning Liu*, Qi Liu*, Xiaohai Yang*, Fang Zhang, Xinda Li, Yuanwu Ma, Feifei Guan, Xin Zhao, Zhiwei Li, Lianfeng Zhang, and Xin Ye. Hepatitis B Virus-Upregulated LNC-HUR1 Promotes Cell Proliferation and Tumorigenesis by Blocking p53 Activity. Hepatology, 2018. PMID: 29790592. *co-first author.
6. Ningning Liu*, Jinfang Zhang*, Xiaohai Yang, Tong Jiao, Xin Zhao, Wenxia Li, Jianhua Zhu, Pu Yang, Jianping Jin, Jirun Peng, Zhiwei Li, and Xin Ye. HDM2 Promotes NEDDylation of Hepatitis B Virus HBx to Enhance its Stability and Function. Journal of Virology, 2017. PMID: 28592528. *co-first author.
7. Ningning Liu, Tong Jiao, Yan Huang, Wenjun Liu, Zhiwei Li, and Xin Ye. Hepatitis B Virus Regulates Apoptosis and Tumorigenesis through the MicroRNA-15a-Smad7-Transforming Growth Factor Beta Pathway. Journal of Virology, 2015. PMID: 25540364.
8. Ningning Liu, Jinfang Zhang, Tong Jiao, Zhiwei Li, and Xin Ye. Hepatitis B Virus Inhibits Apoptosis of Hepatoma Cells by Sponging the MicroRNA-15a/16 Cluster. Journal of Virology, 2013. PMID: 24089558.