MD ABDUL MAZID Researcher/Principal Investigator
Guangzhou Institutes of Biomedicine and Health (GIBH)
Email:mazid@gibh.ac.cn
Phone number:+8613622756579
Address:No. 190 Kaiyuan Avenue, Huangpu District, Guangzhou
Research Areas
Totipotency & pluripotency, Modeling human & NHP embryonic development and lineage specifications, Regenerative medicine, Cell therapy, Organoids
Admission Information
Admission Specialties: Cell Biology, Biochemistry and Molecular Biology, Bioinformatics, Biomedicine
Research Directions: Totipotency & Pluripotency, Human and Non-human Primate Early Embryonic Development, Construction of Specialized Lineage Models, Regenerative Medicine, Cell Therapy, Organoids
Education Experience
2014-09--2020-01 Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences Ph.D. in Science
2007-01--2008-06 University of Rajshahi, Bangladesh Master of Science
2003-01--2006-12 University of Rajshahi, Bangladesh Bachelor of Science
Publications
- Md. Abdul Mazid#*, Carl Ward#, Zhiwei Luo#, Chuanyu Liu#, Yunpan Li, Yiwei Lai, Liang Wu, Jinxiu Li, Wenqi Jia, Yu Jiang, Hao Liu, Lixin Fu, Yueli Yang, David P. Ibañez, Junjian Lai, Xiaoyu Wei, Juan An, Pengcheng Guo, Yue Yuan, Qiuting Deng, Yang Wang, Ying Liu, Fei Gao, Junwen Wang, Shahriar Zaman, Baoming Qin, Guangming Wu, Patrick H. Maxwell, Xun Xu, Longqi Liu*, Wenjuan Li*, Miguel A. Esteban* (2022). Rolling back of human pluripotent stem cells to an 8-cell embryo-like stage. Nature 605, 315-324. (Impact Factor = 55). #First author, *Corresponding author.
- Jing Cao#, Wenjuan Li#, Jie Li#, Md. Abdul Mazid#, Chunyang Li#, Yu Jiang#, Wenqi Jia#, Zhaodi Liao, Shiyu Sun, Jiqiang Fu, Yan Wang, Yong Lu, Yuting Xu, Yanhong Nie, Xinyan Bian, Changshan Gao, Xiaotong Zhang, Liansheng Zhang, Yunpan Li, Lixin Fu, Hao Liu, Junjian Lai, Yang Wang, Yue Yuan, Yiwei Lai, Longqi Liu, Xiaolong Wang, Qiang Sun*, Miguel A. Esteban*, Zhen Liu* (2023). Live Birth of Chimeric Macaque Monkey with High Contribution from Homologous Embryonic Stem Cells. Cell 186, 4996–5014. (Impact Factor = 48.9). #First author, *Corresponding author.
- Yueli Yang#, Wenqi Jia#, Zhiwei Luo, Yunpan Li, Hao Liu, Lixin Fu, Jinxiu Li, Yu Jiang, Junjian Lai, Haiwei Li, Babangida Jabir Saeed, Yi Zou, Yuan Lv, Liang Wu, Ting Zhou, Yongli Shan, Chuanyu Liu, Yiwei Lai, Longqi Liu, Andrew P. Hutchins, Miguel A. Esteban*, Md. Abdul Mazid*, Wenjuan Li* (2024). VGLL1 cooperates with TEAD4 to control human trophectoderm lineage specification. Nature Communications 15, 583. (Impact Factor = 17.20). #First author, *Corresponding author.
- Mazid Md. Abdul#, David P. Ibañez, Ping Zhao, Hao Liu, Xiaofen Zhong, Yingying Li, Meng Zhang, Wenjuan Li, Yunpan Li, Carl Ward, Shuhan Chen, Dongye Wang, Baoming Qin, Miguel A. Esteban, Xiwei Wang*, Wenxia Fan*, Zhiwei Luo (2019). Generation of an induced pluripotent stem cell line (GIBHi003-A) from a Parkinson's disease patient with mutant PINK1 (p. I368N). Stem Cell Research, 41. (Impact Factor = 0.8). #First author, *Corresponding author.
- Juan Zhang#*, Lamisa Ataei, Kirti Mittal, Liang Wu, Lauren Caldwell, Linh Huynh, Shahil Sarajideen, Kevin Tse, Marie-Michelle Simon, Md. Abdul Mazid, David P. Cook, Daniel Trcka, Tony Kwan, Michael M. Hoffman, Jeffrey L. Wrana, Miguel A. Esteban, Miguel Ramalho-Santos* (2025). LINE1 and PRC2 control nucleolar organization and repression of the 8C state in human ESCs. Dev Cell. 60(2), 186-203. (Impact Factor = 10.70). #First author, *Corresponding author.
- Jinxiu Li#, Lixin Fu#, Yunpan Li#, Wei Sun, Yao Yi, Wenqi Jia, Haiwei Li, Hao Liu, Pengcheng Guo, Yang Wang, Yue Shen, Xiuqing Zhang, Yuan Lv, Baoming Qin, Wenjuan Li, Chuanyu Liu, Longqi Liu, Md Abdul Mazid, Yiwei Lai, Miguel A Esteban, Yu Jiang*, Liang Wu* (2024). A single-cell chromatin accessibility dataset of human primed and naïve pluripotent stem cell-derived teratoma. Sci Data.11(1), 725. (Impact Factor = 6.90). #First author, *Corresponding author.
- Jiantao Shi#, Qing Chen, Jianheng Lai, Jieying Zhu, Ran Zhang, Md Abdul Mazid, Dongwei Li, Huanxing Su*, Dajiang Qin* (2024). Impact of c-JUN deficiency on thalamus development in mice and human neural models. Cell Biosci. 14(1),149. (Impact Factor = 9.606). #First author, *Corresponding author.
- Jiaowei Wang#, Wenguang Xie#, Nan Li#, Wenjuan Li#, Zhishuai Zhang#, Nana Fan, Zhen Ouyang, Yu Zhao, Chengdan Lai, Hao Li, Mengqi Chen, Longquan Quan, Yunpan Li, Yu Jiang, Wenqi Jia, Lixin Fu, Md. Abdul Mazid, Yanling Zhu, Patrick H. Maxwell, Guangjin Pan*, Miguel A. Esteban*, Zhen Dai*, and Liangxue Lai* (2023). Generation of a Humanized Mesonephros in Pigs from Induced Pluripotent Stem Cells via Embryo Complementation. Cell Stem Cell 30(9), 1235-1245. (Impact Factor = 21.80). #First author, *Corresponding author.
- Jie Li#, Qingyuan Zhu#, Jing Cao#, Ying Liu#, Yong Lu#, Yining Sun, Qian Li, Yiming Huang, Shenshen Shang, Xinyan Bian, Chunyang Li, Liansheng Zhang, Yan Wang, Yanhong Nie, Jiqiang Fu, Wenjuan Li, Md. Abdul Mazid, Yu Jiang, Wenqi Jia, Xiaolong Wang, Yidi Sun, Miguel A. Esteban, Qiang Sun*, Fan Zhou*, Zhen Liu* (2023). Cynomolgus monkey embryo model captures gastrulation and early pregnancy. Cell Stem Cell 30(4), 362-377. (Impact Factor = 21.80). #First author, *Corresponding author.
- Isaac A. Babarinde, Gang Ma, Yuhao Li, Boping Deng, Zhiwei Luo, Hao Liu, Mazid Md. Abdul, Carl Ward, Minchun Chen, Xiuling Fu, Liyang Shi, Martha Duttlinger, Jiangping He, Li Sun, Wenjuan Li, Qiang Zhuang, Guoqing Tong, Jon Frampton, Jean-Baptiste Cazier, Jiekai Chen, Ralf Jauch, Miguel A. Esteban and Andrew P. Hutchins (2021). Transposable element sequence fragments incorporated into coding and noncoding transcripts modulate the transcriptome of human pluripotent stem cells. Nucleic Acids Research, 49(16). (Impact Factor = 16.80). #First author, *Corresponding author.
- Li Chen, Qiaoqiao Tong, Xiaowen Chen, Penglei Jiang, Hua Yu, Qianbing Zhao, Lingang Sun, Chao Liu, Bin Gu, Yuping Zheng, Lijiang Fei, Xiao Jiang, Wenjuan Li, Giacomo Volpe, Mazid MD. Abdul, Guoji Guo, Jin Zhang, Pengxu Qian, Qiming Sun, Dante Neculai, Miguel A. Esteban, Chen Li, Feiqiu Wen and Junfeng Ji (2021). PHC1 maintains pluripotency by organizing genome-wide chromatin interactions of the Nanog locus. Nature Communications, 12(1). (Impact Factor = 17.20). #First author, *Corresponding author.
- Zhang M, Lai Y, Krupalnik V, Zhou J, Guo P, Xu Y, Yu Z, Guo X, Liu L, Li W, Abdul M M, Ma G, Li N, Fu X, Lv Y, Wang L, Tariq M, Luo Z, Zhang H, Huang Y, Qin X, Chen S, Wang D, Ward C, Zhang X, He M, Ibañez DP, Liu H, Li Y, Kanwal S, Zhou J, Feng Y, Di Vicino U, Bao X, Wu G, Schambach A, Wang H, Gao F, Qin B, Hutchins AP, Hartmann C, Cosma MP, Yan Q, Chen R, Volpe G, Hanna JH, and Esteban MA (2020). β-Catenin safeguards the ground state of mouse pluripotency by strengthening the robustness of the transcriptional apparatus. Science Advances, 6(29). (Impact Factor = 14.10). #First author, *Corresponding author.
- Yunpan Li, David P. Ibanez, Wenxia Fan, Ping Zhao, Shuhan Chen, Mazid Md. Abdul, Yu Jiang, Lixin Fu, Zhiwei Luo, Zhenhua Liu, Yueli Yang, Jifeng Guo, Giacomo Volpe, Shahzina Kanwal, Dongye Wang, Beisha Tang and Wenjuan Li (2020). Generation of an induced pluripotent stem cell line (GIBHi004-A) from a Parkinson's disease patient with mutant DJ-1/PARK7 (p.L10P). Stem Cell Research, 46. (Impact Factor = 0.8). #First author, *Corresponding author.
- Meng Zhang, David P. Ibañez, Wenxia Fan, Hao Liu, Xiaofen Zhong, Xiwei Wang, Yingying Li, Mazid Md. Abdul, Wenjuan Li, Yunpan Li, Carl Ward, Shuhan Chen, Dongye Wang, Baoming Qin, Miguel A. Esteban, Ping Zhao, Zhiwei Luo (2019). Generation of a PARK2 homozygous knockout induced pluripotent stem cell line (GIBHi002-A-1) with two common. Stem Cell Research, 41. (Impact Factor = 0.8). #First author, *Corresponding author.
- He, J, Fu, X, Zhang, M, He, F, Li, W, Abdul, M. M, Zhou, J, Sun, L, Chang, C, Li, Y, Liu, H, Wu, K, Babarinde, I. A, Zhuang, Q, Loh, Y. H, Chen, J, Esteban, M. A, … Hutchins, A. P. (2019). Transposable elements are regulated by context specific patterns of chromatin marks in mouse embryonic stem cells. Nature Communications, 10(1), 34. (Impact Factor = 17.20). #First author, *Corresponding author.
- Zhuang Qiang, Li Wenjuan, Benda Christina, Huang Zhijian, Ahmed Tanveer, Liu Ping, Guo Xiangpeng, Ibañez David P, Luo Zhiwei, Zhang Meng, Abdul Mazid Md, Yang Zhongzhou, Yang Jiayin, Huang Yinghua, Zhang Hui, Huang Dehao, Zhou Jianguo, Zhong Xiaofen, Zhu Xihua, Fu Xiuling, Fan Wenxia, Liu Yulin, Xu Yan, Ward Carl, Khan Muhammad Jadoon, Kanwal Shahzina, Mirza Bushra, Tortorella Micky D, Tse Hung-Fat, Chen Jiayu, Qin Baoming, Bao Xichen, Gao Shaorong, Hutchins Andrew P, Esteban Miguel A, (2018). NCoR/SMRT co repressors cooperate with c-MYC to create an epigenetic barrier to somatic cell reprogramming. Nature Cell Biology, 20, 400-412. (Impact Factor = 22.60). #First author, *Corresponding author.
Patents
(1) Culture Medium and Method for Directed Differentiation of Monkey Naïve Pluripotent Stem Cells into Hypoblast-like Cells, Invention Patent, 2026, 1st Author, Patent No.: 2026105021219
(2) Culture Medium and Method for Directed Differentiation of Naïve Pluripotent Stem Cells into Amnion-like Cells, Invention Patent, 2026, 1st Author, Patent No.: 2026102134145
(3) EMBRYO-LIKE MODEL, AND CONSTRUCTION METHOD THEREFOR AND USE THEREOF, Invention Patent, 2023, 3rd Author, Patent No.: PCT/CN2023/118079
(4) Media and Methods for Producing Human Cells and Tissues from Teratoma, Organoids and Embryoid Bodies, Invention Patent, 2022, 3rd Author, Patent No.: PCT/CN2022/081499
(5) Culture Medium and Method for Producing Human Cells and Tissues from Teratoma, Organoids and Embryoid Bodies, Invention Patent, 2022, 3rd Author, Patent No.: 202211317527.8
(6) Culture Medium and Method for Establishing and Maintaining Early Embryo-like Cells, Invention Patent, 2020, 2nd Author, Patent No.: 202011256758.3
(7) Media and Methods for Establishing and Maintaining Early Embryo-Like Cells, Invention Patent, 2020, 2nd Author, Patent No.: PCT/CN2020/128091
Conferences
(1)From Decay to Renewal: Harnessing the Potentials of Human Totipotent and Pluripotent Cells for Rejuvenation 2025-04-06
(2)Stem Cell Research and Medical Innovation 15th Singapore Stem Cell Society Symposium 2023-12-08
Honors & Distinctions
Talent/Honors
- 2022: National Foreign Expert Individual Program
- 2022: Elite Talent of Huangpu District & Guangzhou Development District
- 2020: CAS President's International Fellowship Initiative (CAS-PIFI) – Special Talent
Student Awards
- 2018–2019: Excellence in Student Award, Guangzhou Institutes of Biomedicine and Health
- 2014: CAS-TWAS President's Fellowship
- 2006–2007: UGC Janata Bank Excellence Scholarship
- 2003–2006: Excellence Scholarship, University of Rajshahi, Bangladesh