Email: liu_xingguo@gibh.ac.cn
Telephone: 020-32015225
Mobile phone:
Address:NO.190, Kaiyuan avenue, Sceince partk, guangzhou, China
Postcode: 510530
Research Areas
The function of cellular signal in the modulation of stem cell fates
The pathogenesis of human mitochondrial diseases and stem cell treatment
Education
2002-2007：Bioscience and technology Institute, Tsinghua University, Ph.D.
Experience
Work Experience
2007-2010: Thomas Jefferson University, post doctor
Honors & Distinctions
2012, Natural science outstanding youth of Guangdong province
2011, One hundred person project of the Chinese academy of sciences
2011, Young scientists award of the international institute of physics
Publications
Papers
1. Ying, Z., Chen K., Zheng L., …& Liu, X*. (2016). Transient activation of mitoflashes modulates Nanog at the early phase of somatic cell reprogramming. Cell Metabolism, 23(1): 220-226.
2. Li, S., Guo, J., Ying, Z., ... & Liu, X*. (2015). Valproic acid‐induced hepatotoxicity in alpers syndrome is associated with mitochondrial permeability transition pore opening‐dependent apoptotic sensitivity in an induced pluripotent stem cell model. Hepatology, 61(5), 1730-1739.
3. Wu, Y., Chen, K., Liu, X., ... & Liu, X*. (2015). Srebp‐1 Interacts with c‐Myc to Enhance Somatic Cell Reprogramming. Stem Cells, 34(1): 83-92.
4. Yang, L., Long, Q., Liu, J., ... & Liu, X*. (2015). Mitochondrial fusion provides an ‘initial metabolic complementation’ controlled by mtDNA. Cellular and Molecular Life Sciences, 72(13):2585-2598.
5. Long, Q., Zhao, D., Fan, W., ... & Liu, X*. (2015). Modeling of Mitochondrial Donut Formation. Biophysical Journal, 109(5), 892-899.
6. Bao, F., Shi, H., Long, Q., …& Liu, X*. (2016). Mitochondrial Membrane Potential-dependent Endoplasmic Reticulum Fragmentation is an Important Step in Neuritic Degeneration. CNS Neuroscience & Therapeutics APR 15 2016 | DOI: 10.1111/cns.12547.
7. Liu, W., Long, Q., Chen, K., ... & Liu, X*. (2013). Mitochondrial metabolism transition cooperates with nuclear reprogramming during induced pluripotent stem cell generation. Biochemical and Biophysical Research Communications, 431(4), 767-771.
8. Liu, X., Weaver, D., Shirihai, O., & Hajnóczky, G. (2009). Mitochondrial ‘kiss‐and‐run’: interplay between mitochondrial motility and fusion–fission dynamics. The EMBO Journal, 28(20), 3074-3089.
9. Liu, X., & Hajnoczky, G. (2011). Altered fusion dynamics underlie unique morphological changes in mitochondria during hypoxia–reoxygenation stress. Cell Death & Differentiation, 18(10), 1561-1572.
10. Weaver, D., Eisner, V., Liu, X., … & Hajnóczky, G. (2014). Distribution and apoptotic function of outer membrane proteins depend on mitochondrial fusion. Molecular Cell, 54(5), 870-878. (co-first author)
11. Liu, X., & Hajnóczky, G. (2009). Ca2+-dependent regulation of mitochondrial dynamics by the Miro–Milton complex. The International Journal of Biochemistry & Cell Biology, 41(10), 1972-1976.
12. Twig, G., Liu, X., Liesa, M., ... & Shirihai, O. S. (2010). Biophysical properties of mitochondrial fusion events in pancreatic β-cells and cardiac cells unravel potential control mechanisms of its selectivity. American Journal of Physiology-Cell Physiology, 299(2), C477-C487. (co-first author)
13. Wu, Y., Li, Y., Zhang, H., ... Liu, X.,… & Pei, D. (2015). Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming. Nature Cell Biology, 17(6), 715-725.
Conferences
Attending Domestic and national conferences for many tmes.