General

Dr. Junfa Yin, 

Research Center for Eco-Environmental Sciences, 

Chinese Academy of Sciences

Email: jfyin@rcees.ac.cn
Telephone: 010-62849611
Address: 18 Shuangqing Road, Haidian District, Beijing
Postcode: 100085

Research Areas

1. Environmental analytical chemistry ( Liquid Chromatography-Mass Spectrometry)

2. High selectivity and sensitivity detection of DNA damage

3. Development and application of functional materials and environmental nanomaterials

Publications

(1) Citrate-functionalized osmium nanoparticles with peroxidase-like specific activity for highly efficient degradation of phenolic pollutants, CHEMICAL ENGINEERING JOURNAL, 2023, 通讯作者

(2) Magnetic multi-enzyme cascade combined with liquid chromatography tandem mass spectrometry for fast DNA digestion and quantitative analysis of 5-hydroxymethylcytosine in genome of human bladder cancer T24 cells induced by tetrachlorobenzoquinone, JOURNAL OF CHROMATOGRAPHY A, 2022, 通讯作者

(3) Selective extraction and detection of beta-agonists in swine urine for monitoring illegal use in livestock breeding, FOOD CHEMISTRY, 2020, 第 3 作者

(4) Immobilized Multi-Enzyme Cascade Reactor, PROGRESS IN CHEMISTRY, 2020, 通讯作者

(5) 固定化多酶级联反应器, Immobilized Multi-Enzyme Cascade Reactor, 化学进展, 2020, 第 5 作者

(6) Bioaccumulation and transfer characteristics of dechlorane plus in human adipose tissue and blood stream and the underlying mechanisms, SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 第 1 作者

(7) Fluorescent imaging of cytoplasmic nucleolin in live cells by a functionalized-engineered aptamer, CHEMICAL COMMUNICATIONS, 2020, 第 1 作者

(8) Profiling of epigenetic DNA modifications by advanced liquid chromatography-mass spectrometry technologies, TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2019, 第 3 作者

(9) Liquid chromatography- mass spectrometry for analysis of DNA damages induced by environmental exposure, TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2019, 第 1 作者

(10) Profiling of epigenetic DNA modifications by advanced liquid chromatography-mass spectrometry technologies, TRENDS IN ANALYTICAL CHEMISTRY, 2019, 第 3 作者

(11) Chemical etching of pH- sensitive aggregationinduced emission- active gold nanoclusters for ultra- sensitive detection of cysteine, NANOSCALE, 2019, 第 4 作者

(12) Elevated 8-oxo-7,8-dihydro-2 '-deoxyguanosine in genome of T24 bladder cancer cells induced by halobenzoquinones, JOURNAL OF ENVIRONMENTAL SCIENCES, 2018, 第 2 作者

(13) Multienzyme cascade bioreactor for a 10 min digestion of genomic dna into single nucleosides and quantitative detection of structural dna modifications in cellular genomic dna, ACS APPLIED MATERIALS & INTERFACES, 2018, 第 1 作者

(14) A multi-enzyme cascade bioreactor for ten-minute digestion of genomic DNA into single nucleosides and quantitative detection of structural DNA modifications in cellular genomic DNA, ACS Applied Materials & Interfaces, 2018, 第 1 作者

(15) Detection of 8-hydroxydeoxyguanosine (8-OHdG) as a biomarker of oxidative damage in peripheral leukocyte DNA by UHPLC–MS/MS, JOURNAL OF CHROMATOGRAPHY B, 2017, 第 3 作者

(16) 级联固定化酶反应器的制备及在核酸修饰分析中的应用, 第21届全国色谱学术报告会及仪器展览会会议论文集, 2017, 第 1 作者

(17) Oxidative stress and immunotoxicity induced by graphene oxide in zebrafish, AQUATIC TOXICOLOGY, 2016, 第 2 作者

(18) 高效液相色谱法测定细胞内的三种能量代谢物, 中国化学会第十一届全国生物医药色谱及相关技术学术交流会(大会特邀报告及墙报)论文摘要集, 2016, 第 3 作者

(19) Three-Enzyme Cascade Bioreactor for Rapid Digestion of Genomic DNA into Single Nucleosides, ANALYTICAL CHEMISTRY, 2016, 第 1 作者

(20) 分子印迹纳米材料用于DNA损伤的荧光成像分析, 第二十届全国色谱学术报告会及仪器展览会, 2015, 第 1 作者

(21) 级联固定化酶微反应器的制备及用于DNA损伤分析, 第二十届全国色谱学术报告会及仪器展览会, 2015, 第 5 作者

(22) 有机-无机杂化毛细管整体基质DNA微酶反应器的制备与应用, 第二十届全国色谱学术报告会及仪器展览会, 2015, 第 3 作者

(23) A fluorophore-conjugated ascorbic acid functions for the visualization of sodium vitamin C transporters in living cells, ANALYTICAL METHODS, 2015, 第 1 作者

(24) 荧光修饰抗坏血酸酯的合成及细胞中SVCTs成像分析, 第二十届全国色谱学术报告会及仪器展览会, 2015, 第 4 作者

(25) Plastic antibody for DNA damages: Fluorescent imaging of BPDE-dG adducts in genomic DNA, Analyst, 2013, 第 1 作者

(26) Study of cytotoxic effects of single-walled carbon nanotubes functionalized with different chemical groups on human MCF7 cells, CHEMOSPHERE, 2013, 第 4 作者

(27) 在线MISPE-HPLC技术用于河水中双酚A类污染物的测定, 第七届全国环境化学学术大会, 2013, 第 1 作者

(28) Polyvinyl Pyrrolidone Promotes DNA Cleavage by a ROS-Independent and Depurination Mechanism, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2013, 第 5 作者

(29) Capillary Monolithic Bioreactor of Immobilized Snake Venom Phosphodiesterase for Mass Spectrometry Based Oligodeoxynucleotide Sequencing, ANALYTICAL CHEMISTRY, 2012, 第 3 作者

(30) 基于整体柱微酶反应器的DNA测序方法研究, 中国化学会第28届学术年会, 2012, 第 3 作者

(31) 分子印迹纳米材料用于BPDE-DNA加合物的高灵敏检测, 全国生物医药色谱及相关技术学术交流会, 2012, 第 1 作者

(32) Size-dependent toxicity of nano-C60 aggregates: More sensitive indication by apoptosis-related Bax translocation in cultured human cells., Environm. Sci. & Technol., 2012, 

(33) Size-Dependent Toxicity of Nano-C-60 Aggregates: More Sensitive Indication by Apoptosis-Related Bax Translocation in Cultured Human Cell, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2012, 第 3 作者

(34) Interaction of Human Serum Album and C-60 Aggregates in Solution, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2011, 第 3 作者

(35) 基于适配体的有机聚合物HPLC整体柱对靶蛋白的提取, 第六届全国环境化学学术大会论文集, 2011, 第 2 作者

(36) 基于固定化微酶反应器的DNA测序方法的研究, 第六届全国环境化学学术大会论文集, 2011, 第 2 作者

(37) MISPE-HPLC法用于水中痕量阿特拉津的测定, 第六届全国环境化学学术大会论文集, 2011, 第 1 作者

(38) Dummy molecularly imprinted polymer for selective screening of trace bisphenols in river water, ANALYTICAL METHODS, 2011, 第 1 作者

(39) Molecularly imprinted nanotubes for enantioselective drug delivery and controlled release, CHEMICALCOMMUNICATIONS, 2010, 通讯作者

(40) Inhibition of polymerase activity by pristine fullerene nanoparticles can be mitigated by abundant proteins, CHEMICAL COMMUNICATIONS, 2010, 第 3 作者

(41) 替代模板分子印迹技术在环境污染物痕量分析中的应用, 2010年全国生物医药色谱学术交流会论文集, 2010, 第 1 作者

(42) Molecularly imprinted nanotubes for enantio-selective drug delivery and controlled release (Cover), Chemical Communications, 2010, 第 1 作者

(43) Fluorescently Imaged Particle Counting Immunoassay for Sensitive Detection of DNA Modifications, ANALYTICAL CHEMISTRY, 2010, 第 4 作者

(44) Pseudo-template molecularly imprinted polymer for selective screening of trace beta-lactam antibiotics in river and tap water, JOURNAL OF CHROMATOGRAPHY A, 2010, 第 1 作者

(45) Fabrication and fluorescence imaging of human low-density lipoprotein coatings for highly efficient capillary electrophoresis separation of basic proteins, ELECTROPHORESIS, 2009, 第 1 作者

(46) Improved preparation and identification of aristolochic acid-DNA adducts by solid-phase extraction with liquid chromatography-tandem mass spectrometry, JOURNAL OF ENVIRONMENTAL SCIENCES, 2009, 第 4 作者

(47) Interaction Between Water-soluble Hydroxylated Single-wall Carbon Nanotubes and Human Serum Albumin, CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2009, 第 2 作者

(48) Highly sensitive detection of human thrombin in serum by affinity capillary electrophoresis/laser-induced fluorescence polarization using aptamers as probes, JOURNAL OF CHROMATOGRAPHY A, 2009, 第 5 作者

(49) 水溶性羟基化单壁碳纳米管与人血清白蛋白之间的相互作用研究, Interaction Between Water-soluble Hydroxylated Single-wall Carbon Nanotubes and Human Serum Albumin, 高等学校化学学报, 2009, 第 2 作者

(50) Improved preparation and identification of aristolochic acid-DNA adducts by solid-phase extraction with liquid chromatography-tandem mass spectrometry, JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA, 2009, 第 4 作者

(51) p- tert-Butylcalix8arene-bonded silica monoliths for liquid chromatography, JOURNAL OF CHROMATOGRAPHY A, 2008, 第 1 作者

(52) Focusing and stabilization of bis-intercalating dye-DNA complexes for high-sensitive CE-LIF DNA analysis, ELECTROPHORESIS, 2008, 第 3 作者

(53) Preparation, identification and analysis of stereoisomeric anti-benzo apyrene diol epoxide–deoxyguanosine adducts using phenyl liquid chromatography with diode array, fluorescence and tandem mass spectrometry detection, JOURNAL OF CHROMATOGRAPHY A, 2008, 第 2 作者

(54) 脂蛋白涂层毛细管电色谱法的应用, 2008年全国生物医药色谱交流会论文集, 2008, 第 1 作者

(55) Macroporous polymer monoliths fabricated by using a metal-organic coordination gel template, CHEMICAL COMMUNICATIONS, 2007, 第 1 作者

(56) Molecularly imprinted solid-phase extraction for rapid screening of mycophenolic acid in human plasma, JOURNAL OF CHROMATOGRAPHY B, 2006, 第 1 作者

(57) Purification and determination of stachyose in Chinese artichoke ( Stachys Sieboldii Miq.) by high-performance liquid chromatography with evaporative light scattering detection, TALANTA, 2006, 第 1 作者

(58) Rapid and efficient chiral separation of nateglinide and its l-enantiomer on monolithic molecularly imprinted polymers, JOURNAL OF CHROMATOGRAPHY A, 2005,  第 1 作者

Students

已指导学生

宋媛媛  硕士研究生  070302-分析化学  

徐田  硕士研究生  077601-环境科学  

陈少坤  硕士研究生  085229-环境工程  

现指导学生

贾蒙  硕士研究生  085700-资源与环境