• Soil Environmental Chemistry
• Environmental Computational Chemistry
• Computational Toxicology

• PhD, Soil Science, Institute of Soil Science, Chinese academy of Sciences (CAS), 2004-2007
• M.S., Physical Chemistry, Nanjing University of Science and Technology (NJUST), 2001-2004
• B.E., Chemical Engineering and Technology, Shandong University of Technology (SDUT), 1997-2001

   

• Associate professor, Institute of Soil Science, Chinese academy of Sciences (CAS), 2012-Currently
• Assistant professor, Institute of Soil Science, Chinese academy of Sciences (CAS), 2010-2011
• Postdoctoral Fellow, School of Environment, Nanjing University, 2007-2009

• Award for 4th Outstanding Young Scientist by Chinese Society of Soil Science, 2014
• Annual Award for Science & Technology by Institute of Soil Science, CAS, 2020
• First Prize of the Eighteenth Science & Technology Award by Chinese Society of Soil Science, 2023
• Award for Excellence in Supervision of M.S. Thesis by Ministry of Education, Juangsu Province, 2023

   

Major publications in the recent five years

[1].   Chenggang Gu*, Lezu Shen, Zhengyuan Gao, Xiuli Fan, Xinglun Yang, Zunyao Wang, Cheng Sun, Fang Wang, Xin Jiang. Unveiling the structural requirements for congener-specific biodegradation of polybrominated diphenyl ethers by Burkholderia xenovorans LB400: A combined QSAR study. Environmental Research 2026, 302: 124632.

[2].   Lezu Shen, Chenggang Gu*, Zhengyuan Gao, Xiuli Fan, Xinglun Yang, Dongyun Yan, Zunyao Wang, Cheng Sun, Huan He, Shaogui Yang, Xin Jiang. Computational mapping of CYP450 metabolism for Benzotriazole UV absorbers: Biotransformation pathways, mechanisms and environmental implications demonstrated with UV-P. Ecotoxicology and Environmental Safety 2026, 314: 120052.

[3].   Xiuli Fan, Chenggang Gu*, Zhengyuan Gao, Lezu Shen, Dongyun Yan, Huan He, Xinglun Yang, Yang Song, Mao Ye, Fang Wang, Xin Jiang. Novel regulatory mechanisms of carboxylesterase by soil organic matter: Correlative insights into enzymatic activation and pollutant degradation via multi-spectral and molecular dynamics approaches. J. Hazard. Mater. 2025, 499: 140315.

[4].   Xiuli Fan, Chenggang Gu*, Zhengyuan Gao, Lezu Shen, Xinglun Yang, Yang Song, Yongrong Bian, Qingfeng Xu, Fang Wang, Xin Jiang. Active binding mechanism to superoxide dismutase and toxicological implication for environmentally prevalent phthalates and their hydrolytic products: Coupling in vitro bioassay with molecular dynamics simulation. Int. J. Biol. Macromol. 2025, 311: 143607.

[5].   Xiuli Fan, Chenggang Gu*, Lezu Shen, Zhengyuan Gao, Xinglun Yang, Yongrong Bian, Fang Wang, Xin Jiang. Theoretical insights into the binding of mono/di-ethyl phthalates to superoxide dismutase and associated structural changes impairing antioxidant activity: A coupled molecular docking and dynamics simulation approach. Sci. Total Environ. 2025, 983: 179667.

[6].   Gao ZY, Gu CG*, Fan XL, Shen LZ, Jin ZH, Wang F, Jiang X. Biochemical insights into the biodegradation mechanism of typical sulfonylureas herbicides and association with active enzymes and physiological response of fungal microbes: A multi-omics approach. Environ. Int. 2024, 190: 108906.

[7].   Fan X.L., Gu C.G.*, Jin Z.H., Cai J., Bian Y.R., Wang F., Chen H., Jiang X. Major biotransformation of phthalic acid esters in Eisenia fetida: Mechanistic insights and association with catalytic enzymes and intestinal symbionts. Environ. Int. 2023, 171: 107712.

[8].   Gu C.G.*, Wang L., Jin Z.H., Fan X.L., Gao Z.Y., Yang X.L., Sun C., Jiang X. Congener-specificity, dioxygenation dependency and association with enzyme binding for biodegradation of polybrominated diphenyl ethers by typical aerobic bacteria: Experimental and theoretical studies. Chemosphere 2023, 314: 137697.

[9].   Gu C.G.*, Jin Z.H., Fan X.L., Ti Q.Q., Yang X.L., Sun C., Jiang X.^* Comparative evaluation and prioritization of key influences on biodegradation of 2,2′,4,4′-tetrabrominated diphenyl ether by bacterial isolate B.xenovorans LB400. J. Environ. Manage. 2023 331:117320

[10].Jin Z.H., Gu C.G. *, Fan X.L., Cai J., Bian Y.R., Song Y., Sun C., Jiang X. Novel insights into the predominant factors affecting the bioavailability of polycyclic aromatic hydrocarbons in industrial contaminated areas using PLS-developed model. Chemosphere 2023, 319: 138033.

[11].Yang L.F., Han W.J., Zhao W.*, Gu C.G.*, Xu Z.H., Jiang X. Mono-/multiadsorption of chlorobenzene compounds on biochar: influence of the properties of the chlorobenzene molecules and biochar. J. Soils Sediments 2023, 23: 2120-2135.

[12].Fan X.L., Gu C.G.*, Cai J., Zhong M., Bian Y.R., Jiang X. Mechanistic insights into primary biotransformation of diethyl phthalate in earthworm and significant SOD inhibitory effect of esterolytic products. Chemosphere 2022, 288: 132491.

[13].Gu C.G.*, Fan X.L., Ti Q.Q., Yang X.L., Bian Y.R., Sun C., Jiang X. Mechanistic insight into hydroxylation of 2,2',4,4'-tetrabromodiphenyl ether during biodegradation by typical aerobic bacteria: Experimental and computational studies. J. Hazard. Mater. 2021, 416: 126132.

[14].Gu C.G., Cai J., Fan X.L., Bian Y.R., Yang X.L., Xia Q.Y., Sun C., Jiang X.* Theoretical investigation of AhR binding property with relevant structural requirements for AhR-mediated toxicity of polybrominated diphenyl ethers. Chemosphere 2020, 249: 126554.

[15].Fan X.L., Gu C.G.*, Cai J., Bian Y.R., Yang X.L., Sun C., Jiang X. Study on active response of superoxide dismutase and relevant binding interaction with bioaccumulated phthalates and key metabolites in Eisenia fetida. Ecotoxicol. Environ. Safe. 2021, 223: 112559.

[16].Ti Q.Q., Gu C.G.*, Cai J., Fan X.L., Zhang Y.P., Bian Y.R., Sun C., Jiang X. Understanding the role of bacterial cellular adsorption, accumulation and bioavailability regulation by biosurfactant in affecting biodegradation efficacy of polybrominated diphenyl ethers. J. Hazard. Mater. 2020, 393: 122382.

[17].Tang J.P., Rong X., Jin D.C., Gu C.G.*, Chen A.W., Luo, S. Biodegradation of phthalate esters in four agricultural soils: Main influencing factors and mechanisms. Int. Biodeterior. Biodegrad. 2020, 147: 104867.

[18].Cai J., Gu C.G.*, Ti Q.Q., Liu C., Bian Y.R., Sun C., Jiang X. Mechanistic studies of congener-specific adsorption and bioaccumulation of polycyclic aromatic hydrocarbons and phthalates in soil by novel QSARs. Environ. Res. 2019, 179: 108838.

[19].Ti Q.Q., Gu C.G.*, Liu C., Cai J., Bian Y.R., Yang X.L., Song Y., Wang F., Sun C., Jiang X. Comparative evaluation of influence of aging, soil properties and structural characteristics on bioaccessibility of polychlorinated biphenyls in soil. Chemosphere 2018, 210: 941-948.

[20].Wang Y., Wang F., Xiang L.L., Gu C.G.,  Redmile-Gordon M.,  Sheng H.J., Wang Z.Q.,  Fu Y.H.,  Bian Y.R., Jiang X. Risk Assessment of Agricultural Plastic Films Based on Release Kinetics of Phthalate Acid Esters. Environ. Sci. Technol. 2021, 55(6): 3676-3685.

[21].Li X.N., Song Y., Bian Y.R., Gu C.G., Yang X.L., Wang F., Jiang X. Insights into the mechanisms underlying efficient Rhizodegradation of PAHs in biochar-amended soil: From microbial communities to soil metabolomics. Environ. Int. 2020, 144: 105995.

• Biological Processes and Toxicological Impacts of Emerging Contaminants
• Enzyme Metabolic Processes and Mechanisms
• Microbial Degradation and Mechanisms
• Mechanism-Facilitaed Developments of Quantitative Structure-Activity Relationships

已指导学生

程吟文  硕士研究生  077601-环境科学  

朱梦荣  硕士研究生  077601-环境科学  

刘畅  硕士研究生  077601-环境科学  

提清清  硕士研究生  077601-环境科学  

蔡君  硕士研究生  077601-环境科学  

范秀丽  硕士研究生  077601-环境科学  

金志华  硕士研究生  077601-环境科学  

现指导学生

沈乐祖  硕士研究生  077601-环境科学  

张如静  硕士研究生  077601-环境科学  

Major Hosting Research Projects

• 2011.01-2013.12, National Natural Science Foundation of China-Youth Program (41001335）
• 2011.07-2014.07, Natural Science Foundation of Jiangsu Province（BK2011886）
• 2014.01-2017.12, National Natural Science Foundation of China-General Program（21377138）
• 2020.01-2023.12, National Natural Science Foundation of China-General Program（41977356）
• 2024.01-2027.12, National Natural Science Foundation of China-General Program（42377406）
• 2021.09-2026.08, Strategic Priority Research Program (Category A) of CAS (XDA28030501）
• 2023.12-2027.11, National Key Research & Development Program of China-subproject (2023YFC3706700)
• 2020.11-2024.10，National Key Research & Development Program of China-subproject（2020YFC1808602）
• 2018.12-2022.11，National Key Research & Development Program of China-subproject（2018YFC1801005）
• 2016.01-2020.12，National Key Research & Development Program of China-subproject（2016YFD0800204