1.   生物医用材料；

2.  表面纳米化和纳米结构效应 ；

3.   抗菌材料；

4.   纳米材料。

材料和化学相关的博士/硕士研究生

083100-生物医学工程
0805J1-纳米科学与技术

生物材料表面改性
基于材料界面性能的细胞行为调控
骨替换和再生材料

2004-09--2009-07   中国科学院上海硅酸盐研究所   博士
2000-09--2004-07   天津城建大学   本科

博士研究生

博士

   

2020-12~现在, 中国科学院深圳先进技术研究院, 研究员
2015-06~2020-12,中国科学院深圳先进技术研究院, 副研究员
2013-06~2015-06,西班牙CIC biomaGUNE生物材料研究中心, 博士后
2009-10~2012-12,澳大利亚悉尼大学（the University of Sydney）, 博士后
2009-07~2009-10,中国科学院上海硅酸盐研究所, 助理研究员

2023-07-23-今,中国生物材料学会生物材料表界面工程分会, 委员
2022-06-30-今,Materials, 期刊编委
2022-06-22-今,Biofunctional Materials, 期刊编委
2019-04-29-今,波兰科学基金合作专家（FN-SOP）,
2017-12-01-今,"Alliance for Design and Application in Tissue Engineering" International Partner,
2016-03-31-2019-03-31,中国医促会骨科生物材料学组委员暨骨科分会委员,

   

（1） Synergistic Photocatalytic and Photothermal Antibacterial Activity of (In, Nb) and (Al, Nb) Co‐Doped TiO2 Ceramics, ADVANCED NANOBIOMED RESEARCH, 2023, 通讯作者
（2） Fe-Doped Carbon Dots as NIR-II Fluorescence Probe for In Vivo Gastric Imaging and pH Detection, ADVANCED SCIENCE, 2023, 通讯作者
（3） Antisenescence ZIF-8/Resveratrol Nanoformulation with Potential for Enhancement of Bone Fracture Healing in the Elderly, ACS BIOMATERIALS SCIENCE & ENGINEERING, 2023, 通讯作者
（4） In-situ growth of vertical graphene on titanium by PECVD for rapid sterilization under near-infrared light, CARBON, 2022, 第 7 作者
（5） Nanotopographic features induced by plasma flame modulate the osteoinductivity of titanium alloy, MATERIALS LETTERS, 2022, 通讯作者
（6） NIR-Responsive TiO2 Biometasurfaces: Toward In Situ Photodynamic Antibacterial Therapy for Biomedical Implants, ADVANCED MATERIALS, 2022, 通讯作者
（7） Silicon incorporation into hydroxyapatite nanocarrier counteracts the side effects of vancomycin for efficient chronic osteomyelitis treatment, CHEMICAL ENGINEERING JOURNAL, 2021, 通讯作者
（8） Strontium modulates osteogenic activity of bone cement composed of bioactive borosilicate glass particles by activating Wnt/beta-catenin signaling pathway (vol 5, pg 334, 2020), BIOACTIVE MATERIALS, 2021, 第 10 作者
（9） The synergistic strategies for the immuno-oncotherapy with photothermal nanoagents, WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, 2021, 第 3 作者
（10） Nanosurfacing Ti alloy by weak alkalinity-activated solid-state dewetting (AAD) and its biointerfacial enhancement effect, MATERIALSHORIZONS, 2021, 通讯作者
（11） Recent advances in surface manipulation using micro-contact printing for biomedical applications, SMART MATERIALS IN MEDICINE, 2021, 第 8 作者
（12） Corrigendum to "Enhancement and orchestration of osteogenesis and angiogenesis by a dual-modular design of growth factors delivery scaffolds and 26SCS decoration" Biomaterials 232 (2020) 119645, BIOMATERIALS, 2021, 第 6 作者
（13） Strontium modulates osteogenic activity of bone cement composed of bioactive borosilicate glass particles by activating Wnt/β-catenin signaling pathway, Strontium modulates osteogenic activity of bone cement composed of bioactive borosilicate glass particles by activating Wnt/β-catenin signaling pathway, 生物活性材料, 2020, 第 10 作者
（14） Aligned Biofunctional Electrospun PLGA-LysoGM1 Scaffold for Traumatic Brain Injury Repair, ACS BIOMATERIALS SCIENCE & ENGINEERING, 2020, 第 8 作者
（15） Electron transfer correlated antibacterial activity of biocompatible graphene Nanosheets-TiO2 coatings, CARBON, 2020, 通讯作者
（16） Bispecific T-cell engager (BiTE) immunotherapy of ovarian cancer based on MIL-88A MOF/MC gene delivery system, APPLIED MATERIALS TODAY, 2020, 通讯作者
（17） Enhancement and orchestration of osteogenesis and angiogenesis by a dual-modular design of growth factors delivery scaffolds and 26SCS decoration, BIOMATERIALS, 2020, 通讯作者
（18） Strontium modulates osteogenic activity of bone cement composed of bioactive borosilicate glass particles by activating Wnt/beta-catenin signaling pathway, BIOACTIVE MATERIALS, 2020, 第 10 作者
（19） MODULATION OF THE MICRO/NANOTOPOGRAPHY OF PLASMA-SPRAYED BIOMEDICAL COATINGS FOR ENHANCED OSTEOGENIC ACTIVITY, SURFACE REVIEW AND LETTERS, 2019, 通讯作者
（20） Strong mineralization ability of strontium zinc silicate: Formation of a continuous biomorphic mineralized layer with enhanced osteogenic activity, COLLOIDS AND SURFACES B-BIOINTERFACES, 2019, 通讯作者
（21） Potential of niobium-based thin films as a protective and osteogenic coating for dental implants: The role of the nonmetal elements, MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2019, 通讯作者
（22） 钛种植体表面CuO和Nb2O5共掺杂TiO2涂层的制备及抗菌性能和生物相容性, Preparation of CuO and Nb2O5 Co-doped TiO2 Coating on Titanium Implants and Its Antibacterial Properties and Biocompatibility, 中国表面工程, 2019, 第 5 作者
（23） Sol-gel derived nanosized Sr5(PO4)2SiO4 powder with enhanced in vitro osteogenesis and angiogenesis for bone regeneration applications, CERAMICS INTERNATIONAL, 2019, 第 4 作者
（24） Antibacterial Mesoporous Titania Films with Embedded Gentamicin and Surface Modified with Bone Morphogenetic Protein 2 to Promote Osseointegration in Bone Implants, ADVANCEDMATERIALSINTERFACES, 2019, 第 7 作者
（25） Ca、Ag掺杂对TiO2涂层结构、体外矿化和抗菌性能的影响, Effect of Ca and Ag Doping on Structure, In-vitro Mineralization, and Anti-Bacterial Properties of TiO2 Coatings, 硅酸盐学报, 2019, 第 5 作者
（26） Potential of niobium-based thin films as a protective and osteogenic coating for dental implants: The role of the nonmetal elements, MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2019, 通讯作者
（27） 3D Printing of Mechanically Stable Calcium-Free Alginate-Based Scaffolds with Tunable Surface Charge to Enable Cell Adhesion and Facile Biofunctionalization, ADVANCED FUNCTIONAL MATERIALS, 2019, 第 8 作者
（28） Microstructure Evolution of Plasma- Sprayed MoSi2 Coating at RT-1200 degrees C in Air, JOURNAL OF THERMAL SPRAY TECHNOLOGY, 2018, 第 3 作者
（29） Enhanced osteogenic activity of ti alloy implants by modulating strontium configuration in their surface oxide layers., RSC ADVANCES, 2018, 第 6 作者
（30） Application of MBG as a coating material on mechanically stronger but less degradable ceramic scaffolds for enhanced osteogenesis, MATERIALS LETTERS, 2018, 通讯作者
（31） 抗菌元素对纳米TiO2涂层结构和性能的影响, Influence of Antibacterial Elements on the Structure and Properties of Nanostructured Ti02 Coatings, 表面技术, 2018, 第 7 作者
（32） Strontium incorporation improves the bone-forming ability of scaffolds derived from porcine bone., COLLOIDS AND SURFACES B-BIOINTERFACES, 2018, 第 5 作者
（33） Layered titanates with fibrous nanotopographic features as reservoir for bioactive ions to enhance osteogenesis, APPLIED SURFACE SCIENCE, 2018, 通讯作者
（34） Bioinspired titanium coatings: self-assembly of collagen-alginate films for enhanced osseointegration, JOURNAL OF MATERIALS CHEMISTRY B, 2016, 第 2 作者
（35） Nb-C Nanocomposite Films with Enhanced Biocompatibility and Mechanical Properties for Hard-Tissue Implant Applications, ACS APPLIED MATERIALS & INTERFACES, 2015, 通讯作者
（36） Synergistic effects of hierarchical hybrid micro/nanostructures on the biological properties of Ti-based orthopaedic implants, RSC Advances, 2015, 通讯作者
（37） Enhancing orthopedic implant biocompatibility: refining the nanotopography, Nanomedicine, 2015, 第 1 作者
（38） Interfacial Reaction-Driven Formation of Silica Carbonate Biomorphs with Subcellular Topographical Features and Their Biological Activity, ACS APPLIED MATERIALS & INTERFACES, 2015, 通讯作者
（39） Refining nanotopographical features on bone implant surfaces by altering surface chemical compositions, RSC ADVANCES, 2014, 通讯作者
（40） Ordered HAp nanoarchitecture formed on HAp/TCP bioceramics by ‘nanocarving’ and mineralization deposition and its potential use for guiding cell behavior, Journal of Materials Chemistry B, 2013, 第 1 作者
（41） Delicate Refinement of Surface Nanotopography by Adjusting TiO2 Coating Chemical Composition for Enhanced Interfacial Biocompatibility, ACS APPLIED MATERIALS & INTERFACES, 2013, 通讯作者
（42） Activation and promotion of adipose tissue-derived mesenchymal stem cells by tumour necrosis factor-alpha preconditioning for bone tissue engineering, Journal of Cellular Physiology, 2013, 第 1 作者
（43） The synergistic effect of hierarchical micro/nano-topography and bioactive ions for enhanced osseointegration, BIOMATERIALS, 2013, 第 2 作者
（44） Baghdadite Ceramics Modulate the Crosstalk between Human Adipose Stem Cells and Osteoblasts for Bone Regeneration, Tissue Engineering A, 2013, 第 1 作者
（45） A facile method to in situ formation of hydroxyapatite single crystal architecture for enhanced osteoblast adhesion, JOURNAL OF MATERIALS CHEMISTRY, 2012, 第 1 作者
（46） Bone biomimetic microenvironment induces osteogenic differentiation of adipose tissue-derived mesenchymal stem cells, NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2012, 第 3 作者
（47） Porous scaffolds with tailored reactivity modulate in-vitro osteoblast responses, MATERIALS SCIENCE & ENGINEERING C, 2012, 第 1 作者
（48） Short-term Exposure to Tumour Necrosis Factor-alpha Enables Human Osteoblasts to Direct Adipose Tissue-Derived Mesenchymal Stem Cells into Osteogenic Differentiation, STEMCELLSANDDEVELOPMENT, 2012, 第 1 作者
（49） Nanostructured glass–ceramic coatings for orthopaedic applications, JOURNAL OF THE ROYAL SOCIETY INTERFACE, 2011, 第 1 作者
（50） Enhanced effects of nano-scale topography on the bioactivity and osteoblast behaviors of micron rough ZrO 2 coatings, COLLOIDS AND SURFACES B-BIOINTERFACES, 2011, 第 1 作者
（51） Microstructure, bioactivity and osteoblast behavior of monoclinic zirconia coating with nanostructured surface, ACTA BIOMATERIALIA, 2010, 第 1 作者
（52） Functional Coatings or Films for Hard-Tissue Applications, MATERIALS, 2010, 第 1 作者
（53） Plasma-sprayed CaTiSiO5 ceramic coating on Ti-6Al-4V with excellent bonding strength, stability and cellular bioactivity, JOURNAL OF THE ROYAL SOCIETY INTERFACE, 2009, 第 4 作者
（54） 等离子喷涂纳米氧化锆涂层研究进展, Research Progress in Plasma Sprayed Nanostructured Zirconia Coatings, 中国表面工程, 2009, 第 3 作者
（55） In vitro bioactivity and phase stability of plasma-sprayed nanostructured 3Y-TZP coatings, ACTA BIOMATERIALIA, 2009, 第 1 作者
（56） Phase composition and in-vitro bioactivity of plasma sprayed calcia stabilized zirconia coatings, SURFACE & COATINGS TECHNOLOGY, 2008, 第 1 作者

（1） Bioceramics for skeletal bone regeneration, Woodhead Publishing, 2014-08, 第 1 作者

   

（ 1 ） 新型仿生骨材料的关键技术研发, 负责人, 地方任务, 2016-01--2018-01
（ 2 ） 新型高骨诱导活性人工关节涂层的研发, 负责人, 地方任务, 2017-01--2018-12
（ 3 ） 华南生物医用材料与植入器械创新示范基地, 负责人, 国家任务, 2017-07--2020-12
（ 4 ） 组织工程骨仿生活化及快速血管化研究, 负责人, 地方任务, 2017-06--2020-06
（ 5 ） 生物活性陶瓷表面微环境预调制及其对巨噬细胞行为和骨再生的影响机制, 负责人, 国家任务, 2019-01--2022-12
（ 6 ） 钛合金表面原位介孔化及生长因子负载的促骨整合作用研究, 负责人, 地方任务, 2018-05--2021-04
（ 7 ） 生物材料与组织工程制品调控的免疫微环境对组织再生的影响及机制研究, 参与, 国家任务, 2018-09--2021-06
（ 8 ） 医用聚醚醚酮表面免疫反应时序调控及其促组织修复研究, 参与, 国家任务, 2022-01--2025-12
（ 9 ） 特异占取S蛋白侵染位点的纳米材料设计及其抗新冠研究, 负责人, 国家任务, 2021-10--2023-09

（1）Accelerated bone formation by bioactive ions and growth factor delivery   2019-10-14
（2）Nano-topographic modification of biomaterials for enhanced biological responses   2019-06-05
（3）Surface modification of biomaterials for enhanced biological performance   2018-12-06
（4）基于界面反应的生物形态碳酸锶晶体的形成及其对生物活性的影响研究   中国生物材料大会   2015-11-19
（5）Nobium-Carbon nanocomposite films for orthopaedic implant applications   2015-10-24
（6）Novel method to in-situ formation of hydroxyapatite single crystal architecture for enhanced bioactivity   2012-08-28
（7） Biomimetic single crystal surface Engineering of Bioceramics for enhanced wettability and osteoblast attachment   2012-06-01

The University of Sydney, Australia-Prof. Hala Zreiqat

CIC biomaGUNE, Spain-Prof. Sergio Moya

School of Engineering, Universidad Militar Nueva Granada, Colombia-Prof. Willian Aperador

NanoBioMedical Center, Adam Mickiewicz University, Poland-Prof. Emmerson Coy

Centro de Investigación en Química Aplicada (CIQA), Mexico-Prof. Ron Ziolo

深圳第二人民医院，第四军医大学，上海长海医院

已指导学生

卢丹萍  硕士研究生  085204-材料工程  

邱实  硕士研究生  085204-材料工程  

现指导学生

纪佳雯  硕士研究生  085600-材料与化工  

徐正江  博士研究生  0703Z1-化学生物学  

芮昊  硕士研究生  086000-生物与医药  

罗锦妍  硕士研究生  085600-材料与化工  

丘才杰（常州大学）；

陈晓艺（中科大纳米学院）；

孙伟（中科大纳米学院）；

吴犇（常州大学）。

​

本科生学术培养（课题选择,指导及论文写作）： 

·           悉尼大学工作期间：  一名悉尼大学honor student（已毕业）

·           目前:               一名Tecnun Universidad de Navarra本科生。

博士生学术培养（课题选择，指导及论文写作）： 

·           悉尼大学工作期间:   一名泰国Qiang Mai大学交换培养学生，骨水泥性能优化研究 (已毕业）。

·           目前:               一名CIC biomaGUNE博士研究生，采用LBL技术在医用钛合金表面构建三维无极有机杂化仿生结构以促进骨组织再生。