Our research focuses on engineering microbe to produce natural material and bioactive polymers including protein, polysaccharides, polyesters, and polyamides, et al. 

1997-2001 College of Life Science, Shanxi University, China

2001-2004 Institute of Zoology, Chinese Academy of Sciences, China

2010-2013 Institute of Microbiology, Chinese Academy of Sciences, China

1.  Wenqin Bai, Cameron J. Sargent, Jeong-Mo Choi, Rohit V. Pappu, Fuzhong Zhang*. Covalently-assembled single-chain protein nanostructures with ultra-high stability. Nature Communications. 2019, 10, 3317.

2.  Wenqin Bai, Weitao Geng, Shaojie Wang and Fuzhong Zhang*. Biosynthesis, regulation, and engineering of microbially produced branched biofuels. Biotechnology for Biofuels. 2019, 12:84

3.  Wenqin Bai, Yi-Shu Tai, Jingyu Wang, Jilong Wang, Pooja Jambunathan, Kevin J. Fox, Kechun Zhang*. Engineering Nonphosphorylative Metabolism to Synthesize Mesaconate from D-Xylose and L-Arabinose in Escherichia coli. Metabolic Engineering, 2016 (38): 285–292

4.  Wenqin Bai*, Yufan Cao, Jun Liu, Qinhong Wang, Zhenhu Jia. Improvement of alkalophilicity of an alkaline xylanase Xyn11A-LC from Bacillus sp. SN5 by random mutation and Glu135 saturation mutagenesis. BMC Biotechnology, 2016(16):77

5.  Wenqin Bai, Yanfen Xue, Yueju Zhao, Qinhong Wang, Yanhe Ma*. Structural insight into and mutational analysis of family 11 xylanases: implications for mechanisms of higher pH catalytic adaptation. PLoS One. 2015, Jul 10, 10(7):e0132834.

6.  Wenqin Bai, Yanfen Xue, Cheng Zhou, Yanhe Ma*. Cloning, expression and characterization of an alkali-tolerant xylanase from alkalophilic Bacillus sp. SN5. Biotechnol Appl Biochem. 2015, 62(2):208-17

7.  Wenqin Bai, Cheng Zhou, Yanfen Xue, Chunhsiang Huang, Ruiting Guo, Yanhe Ma*. Three-dimensional structure of an alkaline xylanase Xyn11A-LC from alkalophilic Bacillus sp. SN5 and improvement of its thermal performance by introducing arginines substitutions. Biotechnol Lett. 2014, 36(7):1495-501.

8.  Wenqin Bai, Yanfen Xue, Cheng Zhou, Yanhe Ma*. Cloning, expression and characterization of a novel salt-tolerant xylanase from Bacillus sp. SN5. Biotechnol Lett. 2012, 34(11):2093-9.

1 . Characterization and application of a alkali-tolerant xylanase. ZL201110317121.5 

2 . Characterization and application of a novel salt-tolerant xylanase. ZL201110317110.7

3.  Characterization and application of a bacterial strain  with methyl parathion mineralizing activity. ZL200410081019X

​

现指导学生

高佳琪  博士研究生  071010-生物化学与分子生物学