The aspects of our research interests are designing, synthesizing, and utilizing new molecular systems for stimuli-responsive and biological applications. 

1. Molecular agents for bio-imaging and therapeutic applications (magnetic resonance imaging, multimodal, fluorescence, gene therapy, tumor imaging, activity-based sensing, gadolinium(III) probe).

2. Sustainable photocatalysis enabled by near infrared light irradiation (near-infrared, two-photon absorption, triplet−triplet annihilation upconversion, photoredox catalysis, ruthenium, osmium, iridium).

3.Smart-responsive complexes and polymers (supramolecular electronics; self-assembly; organometallic materials; multi redox-center systems; electro-transfer; mixed-valence compounds; polypyridyl complexes; cyclometalated complexes; ruthenium; triarylamines; near-infrared; electrochromism; electropolymerization)

37. Ming Liu, Jingpi Gao, Yang Zhang, Xin Zhou, Yu Wang, Li Wu, Zhiyuan Tian, Jian-Hong Tang*, Recent Advances in Bioresponsive Macrocyclic Gadolinium(III) Complexes for MR Imaging and Therapy. Dalton Trans. 2025, in press.

36. Yan-Qin He, Jian-Hong Tang*, Anthracene-Based Endoperoxides as Self-Sensitized Singlet Oxygen Carriers for Hypoxic-Tumor Photodynamic Therapy. Adv. Healthcare Mater. 2025, 2403009.

https://doi.org/10.1002/adhm.202403009

35. Jian-Hong Tang⁺, Minrui Luo⁺, Wilhelmina Tsao, Emily Alexandria Waters, Giacomo Parigi, Claudio Luchinat, Thomas J. Meade*, MR Imaging Reveals Dynamic Aggregation of Multivalent Glycoconjugates in Aqueous Solution. Inorg. Chem. 2024, 63, 24662-24671.

https://doi.org/10.1021/acs.inorgchem.4c03878

34. Jingpi Gao, Ming Liu, Li Wu, Zhiyuan Tian*, Jian-Hong Tang*, Yujie Sun*, Activatable Two-Photon-Excited Molecular Fluorescent Probes for Near-Infrared Biosensing and Bioimaging. ACS Appl. Eng. Mater. 2024, 2(11), 2504–2520. 

https://doi.org/10.1021/acsaenm.4c00598

33. Kun Tang, Jiang-Yang Shao, Jikun Li, Shumu Li, Jian-Hong Tang, Ran Duan, Jiannian Yao and Yu-Wu Zhong*, Pyridine-terminated small molecular photocatalyst for water reduction. Chem 2024, 10, 1925-1939.

32. Heike E. Daldrup-Link*, Vidyani Suryadevara, Yasemin Tanyildizi, Kerem Nernekli, Jian-Hong Tang & Thomas J. Meade, Musculoskeletal imaging of senescence. Skelet. Radiol. 2024, 53, 1879–1887.

31. Jian-Hong Tang⁺, Hao Li⁺, Chaonan Yuan, Giacomo Parigi, Claudio Luchinat, and Thomas J. Meade*, Molecular Engineering of Self-Immolative Bioresponsive MR Probes. J. Am. Chem. Soc. 2023, 145(18), 10045–10050. 

30. Jian-Hong Tang*, Yu-Wu Zhong*, Anthracene-Containing Metallacycles and Metallacages: Structures, Properties, and Applications. Inorganics 2022, 10(7), 88.

29. Jian-Hong Tang⁺, Guanqun Han⁺, Guodong Li, Kaili Yan, Yujie Sun*, Near-infrared light photocatalysis enabled by a ruthenium complex-integrated metal–organic framework via two-photon absorption. iScience 2022, 25 (4), 104064.

28. Si-Hai Wu*, Rong Yang, Bin Sun, Jian-Hong Tang, Zhong-Liang Gong, Junjie Ma, Lianhui Wang, Jieqing Liu, Dian-Xue Ma, Jiang-Yang Shao* and Yu-Wu Zhong*, Dual-Emissive Tris-Heteroleptic Ruthenium Complexes: Tuning the DNA-Triggered Ratiometric Emission Response by Ancillary Ligands. Inorg. Chem. 2021, 60 (19), 14810–14819.

27. Zhong-Qiu Li⁺, Jian-Hong Tang⁺, Yan-Qin He, Zhong-Liang Gong, Jiang-Yang Shao, and Yu-Wu Zhong*, Ionic Organic Microcrystals with Bright Deep-Blue Luminescence and Acid/Base Vapor Response. Cryst. Growth Des. 2021, 21 (3), 1854–1860.

26. Yanrong Li*, Sreehari Surendran Rajasree, Ga Young Lee, Jierui Yu, Jian-Hong Tang, Ruidong Ni, Guigen Li, Kendall. N. Houk, Pravas Deria*, and Peter J. Stang*, Anthracene–Triphenylamine-Based Platinum(II) Metallacages as Synthetic Light-Harvesting Assembly. J. Am. Chem. Soc. 2021, 143 (7), 2908–2919. 

25. Si-Hai Wu*, Jiang-Yang Shao, Zifeng Zhao, Junjie Ma, Rong Yang, Na Chen, Jian-Hong Tang*, Zuqiang Bian, and Yu-Wu Zhong*, Ligand Engineering toward Deep Blue Emission in Nonplanar Terdentate Platinum(II) Complexes. Organometallics 2021, 40 (2), 156–165.

24. Jian-Hong Tang, Yujie Sun*, Visible-Light-Driven Organic Transformations Integrated with H₂ Production on Semiconductors. Mater. Adv. 2020, 1, 2155-2162. 

23. Jian-Hong Tang, Yujie Sun*, Interfacing metals and compounds for enhanced hydrogen evolution from water splitting. MRS Bulletin. 2020, 45, 548-554. 

22. Zhi-Juan Li, Jian-Hong Tang, Jiang-Yang Shao, Yu-Wu Zhong*, Near-Infrared Electrochromism of Multilayer Films of an N∧C∧N-Pincer Tri-Ru(II) Complex. Eur. J. Inorg. Chem. 2020, 30, 2882-2888.

21. Yan-Qin He, Jian-Hong Tang, Zhong-Qiu Li, Yu-Wu Zhong*, Syntheses and pH-responsive emissions of pyrid-2-yl-appended para-phenylene oligomers. Tetrahedron. 2020, 76, 131695. 

20. Xiao Shang,   Jian-Hong Tang,   Bin Dong* and  Yujie Sun*, Recent advances of nonprecious and bifunctional electrocatalysts for overall water splitting. Sustain. Energ. Fuels. 2020, 4, 3211-3228. 

19. Yan-Qin He, Werner Fudickar, Jian-Hong Tang*, Heng Wang, Xiaopeng Li, Jun Han, Zhengping Wang, Min Liu, Yu-Wu Zhong, Torsten Linker* and Peter J. Stang*, Capture and Release of Singlet Oxygen in Coordination-Driven Self-Assembled Organoplatinum(II) Metallacycles. J. Am. Chem. Soc. 2020, 142, 5, 2601-2608. 

18. Zhao Chen⁺, Jian-Hong Tang⁺, Wenzhuo Chen, Yao Xu, Heng Wang, Zhe Zhang, Hajar Sepehrpour, Gui-Juan Cheng, Xiaopeng Li, Pingshan Wang, Yue Sun,* and Peter J. Stang*, Temperature and Mechanical Force Responsive Self-Assembled Rhomboidal Metallacycle, Organometallics, 2019, 38, 4244-4249. 

17. Jian-Hong Tang⁺, Yueqi Li⁺, Qingqing Wu⁺, Songjun Hou, Zixiao Wang, Kun Tang, Yue Sun, Hui Wang, Heng Wang, Xiaopeng Li, Jiannian Yao, Colin J. Lambert*, Nongjian Tao*, Yu-Wu Zhong* and Peter J. Stang*, Single-molecule level control of host-guest interactions in metallocycle-C₆₀ complexes, Nat. Commun., 2019, 10, 4599. (Editor’s highlights)

16. Jian-Hong Tang⁺, Ruidong Ni⁺, Yan-Qin He⁺, Ryan T. Vanderlinden, Yanrong Li, Bingbing Shi, Zhong-Yu Li, Heng Wang,* Xiaopeng Li, Yue Sun,* Yu-Wu Zhong,* and Peter J. Stang*, Metal−Organic Pt(II) Hexagonal-Prism Macrocycles and Their Photophysical Properties, Inorg. Chem, 2019, 58, 13376-13381.

15. Bingbing Shi, Zhixuan Zhou, Ryan T. Vanderlinden, Jian-Hong Tang, Guocan, Yu*, Koushik Acharyya, Peter J. Stang*, Spontaneous Supramolecular Polymerization Driven by Discrete Platinum Metallacycle-Based Host–Guest Complexation, J. Am. Chem. Soc. 2019, 141, 11837-11841.

14. Bingbing Shi, Yuezhou Liu, Huangtianzhi Zhu, Ryan T. Vanderlinden, Liqing Shangguan, Ruidong Ni, Koushik Acharyya, Jian-Hong Tang, Zhixuan Zhou, Xiaopeng Li, Feihe Huang*, Peter J. Stang*, Spontaneous Formation of a Cross-Linked Supramolecular Polymer Both in the Solid State and in Solution, Driven by Platinum(II) Metallacycle-Based Host−Guest Interactions, J. Am. Chem. Soc. 2019, 141, 6494−6498.

13. Jiang-Yang Shao, Bin-Bin Cui, Jian-Hong Tang, Yu-Wu Zhong*, Resistive memory switching of transition-metal complexes controlled by ligand design, Coord. Chem. Rev. 2019, 393, 21−36.

12. Jian-Hong Tang⁺, Yue Sun⁺, Zhong-Liang Gong, Zhong-Yu Li, Zhixuan Zhou, Heng Wang, Xiaopeng Li, Manik Lal Saha*, Yu-Wu Zhong* and Peter J. Stang*, Temperature-Responsive Fluorescent Organoplatinum(II) Metallacycles, J. Am. Chem. Soc. 2018, 140, 7723-7729.

11. Jian-Hong Tang, Zhenfeng Cai, Dong Yan, Kun Tang, Jiang-Yang Shao, Chuanlang Zhan, Dong Wang, Yu-Wu Zhong*, Li-Jun Wan, Jiannian Yao, A Molecular Quadripod as a Noncovalent Interfacial Coupling Reagent for Forming Immobilized Coordination

Assemblies, J. Am. Chem. Soc. 2018, 140, 12337-12340.

10. Rui Li, Zhong-Liang Gong, Jian-Hong Tang, Meng-Jia Sun, Jiang-Yang Shao, Yu-Wu Zhong* and Jiannian Yao, Triarylamines with branched multi-pyridine groups: modulation of emission properties by structural variation, solvents, and tris(pentafluorophenyl)borane. Sci. China Chem. 2018, 61(5), 545-556.

9. Jian-Hong Tang, Tian-Ge Sun, Jiang-Yang Shao, Zhong-Liang Gong and Yu-Wu Zhong*, Resistive memory devices based on a triphenylamine-decorated non-precious cobalt(II) bis-terpyridine complex, Chem. Commun. 2017, 53, 11925-11928.

8. Jian-Hong Tang, Jiang-Yang Shao, Yan-Qin He, Si-Hai Wu, Jiannian Yao, Yu-Wu Zhong*, Transition from a Metal-Localized Mixed-Valence Compound to a Fully Delocalized and Bridge-Biased Electrophore in a Ruthenium-Amine-Ruthenium Tricenter System, Chem. Eur. J. 2016, 22(30), 10341-10345.

7. Jian-Hong Tang, Yan-Qin He, Jiang-Yang Shao, Zhong-Liang Gong, Yu-Wu Zhong*, Multistate Redox Switching and Near-Infrared Electrochromism Based on a Star-Shaped Triruthenium Complex with a Triarylamine Core, Sci. Rep. 2016, 6, 35253.

6. Jian-Hong Tang, Chang-Jiang Yao, Bin-Bin Cui and Yu-Wu Zhong*, Ruthenium-Amine Conjugated Organometallic Materials for Multistate Near-IR Electrochromism and Information Storage, Chem. Rec. 2016, 16(2), 754-767.

5. Bin-Bin Cui, Jian-Hong Tang, Yu-Wu Zhong*, Resistive Memory Materials Based on Transition-Metal Complexes, Acta Chim. Sinica 2016, 74(9), 726-733. 

4. Zhongliang Gong , Changjiang Yao , Jiangyang Shao , Haijing Nie , Jianhong Tang, Zhong Yuwu*, Redox-responsive cyclometalated ruthenium and osmium complexes, Sci. Sin. Chim. 2016, 46(10), 1093-1100. 

3. You-Ming Zhang, Fanyuan Meng, Jian-Hong Tang, Yafei Wang, Caifa You, Hua Tan, Yu Liu, Yu-Wu Zhong*, Shijian Su* and Weiguo Zhu*, Achieving near-infrared emission in platinum(II) complexes by using an extended donor–acceptor-type ligand, Dalton Trans. 2016, 45, 5071-5080. 

2. Bin-Bin Cui⁺, Jian-Hong Tang⁺, Jiannian Yao, and Yu-Wu Zhong*, A Molecular Platform for Multistate Near-Infrared Electrochromism and Flip-Flop, Flip-Flap-Flop, and Ternary Memory, Angew. Chem. Int. Ed. 2015, 54(32), 9192-9197.

1. Jian-Hong Tang, Si-Hai Wu, Jiang-Yang Shao, Hai-Jing Nie, Yu-Wu Zhong,* Ruthenium-Amine Electronic Coupling Bridged through Phen-1,3-diyl Versus Phen-1,4-diyl: Reverse of the Charge Transfer Direction, Organometallics 2013, 32(16), 4564-4570.