面向多通道耦合分子成像与精准医疗领域发展需求，以核磁共振成像（MRI）技术为核心，聚焦高性能、靶向特异响应性分子磁共振成像造影剂（对比剂）的设计、制备以及生物性能研究，探索新型磁共振成像造影剂分子在临床生物成像、基因诊疗临床监测等领域的性质应用，构筑基础科学研究与临床应用转化的桥梁。

关键词：磁共振成像、钆分子造影剂、多通道耦合成像与诊疗、基因诊疗、刺激响应光电功能金属有机材料、响应性超分子组装体、发光显示与器件、表界面修饰与组装、超分子自组装、超分子聚合物、电致变色、超分子单分子电子学与器件、大环化学。

每年招收硕士、博士研究生2-4名。

招生专业：有机化学-070303、无机化学-070301

招生方向：有机合成、功能配合物、金属有机、药物化学、超分子化学

课题组成员：

特别研究助理：刘明  博士（liuming@ucas.ac.cn）

博士后:  张阳  博士（yangzhang@ucas.ac.cn）

科研助理：王昱（wangyu204@mails.ucas.ac.cn）

博士在读：高京丕（gaojingpi24@mails.ucas.ac.cn）

硕士在读：周欣（15170076427@163.com）

*长期招聘特别研究助理、博士后、科研助理等岗位！

2013-09--2018-06   中国科学院化学研究所   博士研究生/博士
2009-09--2013-06   湘潭大学   本科/理学学士

  2024年5月入职中国科学院大学长聘教轨助理教授岗位，开展磁共振成像造影剂相关研究。2018年在中国科学院化学研究所钟羽武研究员课题组 获得理学博士学位 (有机化学专业)，并先后在美国犹他大学Peter J. Stang 超分子化学课题组，辛辛那提大学Yujie Sun有机/无机光电催化课题组，和西北大学Thomas J. Meade磁共振成像课题组从事博士后研究，在金属有机光电功能材料，超分子配位自组装，双光子介导的近红外光催化，以及生物酶响应分子钆类磁共振成像造影剂等多学科交叉领域具有丰富的研究经验与研究基础。系列研究成果发表于Nat. Commun., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Chem. Commun., Chem. Eur. J, Inorg. Chem.等权威学术期刊（> 38），申请发明专利三项等。

37. Ming Liu, Jingpi Gao, Yang Zhang, Xin Zhou, Yu Wang, Li Wu, Zhiyuan Tian, Jian-Hong Tang*, Recent Advances in Bioresponsive Macrocyclic Gadolinium(III) Complexes for MR Imaging and Therapy. Dalton Trans. 2025, in press.

36. Yan-Qin He, Jian-Hong Tang*, Anthracene-Based Endoperoxides as Self-Sensitized Singlet Oxygen Carriers for Hypoxic-Tumor Photodynamic Therapy. Adv. Healthcare Mater. 2025, 2403009.

https://doi.org/10.1002/adhm.202403009

35. Jian-Hong Tang⁺, Minrui Luo⁺, Wilhelmina Tsao, Emily Alexandria Waters, Giacomo Parigi, Claudio Luchinat, Thomas J. Meade*, MR Imaging Reveals Dynamic Aggregation of Multivalent Glycoconjugates in Aqueous Solution. Inorg. Chem. 2024, 63, 24662-24671.

https://doi.org/10.1021/acs.inorgchem.4c03878

34. Jingpi Gao, Ming Liu, Li Wu, Zhiyuan Tian*, Jian-Hong Tang*, Yujie Sun*, Activatable Two-Photon-Excited Molecular Fluorescent Probes for Near-Infrared Biosensing and Bioimaging. ACS Appl. Eng. Mater. 2024, 2(11), 2504–2520. 

https://doi.org/10.1021/acsaenm.4c00598

33. Kun Tang, Jiang-Yang Shao, Jikun Li, Shumu Li, Jian-Hong Tang, Ran Duan, Jiannian Yao and Yu-Wu Zhong*, Pyridine-terminated small molecular photocatalyst for water reduction. Chem 2024, 10, 1925-1939.

32. Heike E. Daldrup-Link*, Vidyani Suryadevara, Yasemin Tanyildizi, Kerem Nernekli, Jian-Hong Tang & Thomas J. Meade, Musculoskeletal imaging of senescence. Skelet. Radiol. 2024, 53, 1879–1887.

31. Jian-Hong Tang⁺, Hao Li⁺, Chaonan Yuan, Giacomo Parigi, Claudio Luchinat, and Thomas J. Meade*, Molecular Engineering of Self-Immolative Bioresponsive MR Probes. J. Am. Chem. Soc. 2023, 145(18), 10045–10050. 

30. Jian-Hong Tang*, Yu-Wu Zhong*, Anthracene-Containing Metallacycles and Metallacages: Structures, Properties, and Applications. Inorganics 2022, 10(7), 88.

29. Jian-Hong Tang⁺, Guanqun Han⁺, Guodong Li, Kaili Yan, Yujie Sun*, Near-infrared light photocatalysis enabled by a ruthenium complex-integrated metal–organic framework via two-photon absorption. iScience 2022, 25 (4), 104064.

28. Si-Hai Wu*, Rong Yang, Bin Sun, Jian-Hong Tang, Zhong-Liang Gong, Junjie Ma, Lianhui Wang, Jieqing Liu, Dian-Xue Ma, Jiang-Yang Shao* and Yu-Wu Zhong*, Dual-Emissive Tris-Heteroleptic Ruthenium Complexes: Tuning the DNA-Triggered Ratiometric Emission Response by Ancillary Ligands. Inorg. Chem. 2021, 60 (19), 14810–14819.

27. Zhong-Qiu Li⁺, Jian-Hong Tang⁺, Yan-Qin He, Zhong-Liang Gong, Jiang-Yang Shao, and Yu-Wu Zhong*, Ionic Organic Microcrystals with Bright Deep-Blue Luminescence and Acid/Base Vapor Response. Cryst. Growth Des. 2021, 21 (3), 1854–1860.

26. Yanrong Li*, Sreehari Surendran Rajasree, Ga Young Lee, Jierui Yu, Jian-Hong Tang, Ruidong Ni, Guigen Li, Kendall. N. Houk, Pravas Deria*, and Peter J. Stang*, Anthracene–Triphenylamine-Based Platinum(II) Metallacages as Synthetic Light-Harvesting Assembly. J. Am. Chem. Soc. 2021, 143 (7), 2908–2919. 

25. Si-Hai Wu*, Jiang-Yang Shao, Zifeng Zhao, Junjie Ma, Rong Yang, Na Chen, Jian-Hong Tang*, Zuqiang Bian, and Yu-Wu Zhong*, Ligand Engineering toward Deep Blue Emission in Nonplanar Terdentate Platinum(II) Complexes. Organometallics 2021, 40 (2), 156–165.

24. Jian-Hong Tang, Yujie Sun*, Visible-Light-Driven Organic Transformations Integrated with H₂ Production on Semiconductors. Mater. Adv. 2020, 1, 2155-2162. 

23. Jian-Hong Tang, Yujie Sun*, Interfacing metals and compounds for enhanced hydrogen evolution from water splitting. MRS Bulletin. 2020, 45, 548-554. 

22. Zhi-Juan Li, Jian-Hong Tang, Jiang-Yang Shao, Yu-Wu Zhong*, Near-Infrared Electrochromism of Multilayer Films of an N∧C∧N-Pincer Tri-Ru(II) Complex. Eur. J. Inorg. Chem. 2020, 30, 2882-2888.

21. Yan-Qin He, Jian-Hong Tang, Zhong-Qiu Li, Yu-Wu Zhong*, Syntheses and pH-responsive emissions of pyrid-2-yl-appended para-phenylene oligomers. Tetrahedron. 2020, 76, 131695. 

20. Xiao Shang,   Jian-Hong Tang,   Bin Dong* and  Yujie Sun*, Recent advances of nonprecious and bifunctional electrocatalysts for overall water splitting. Sustain. Energ. Fuels. 2020, 4, 3211-3228. 

19. Yan-Qin He, Werner Fudickar, Jian-Hong Tang*, Heng Wang, Xiaopeng Li, Jun Han, Zhengping Wang, Min Liu, Yu-Wu Zhong, Torsten Linker* and Peter J. Stang*, Capture and Release of Singlet Oxygen in Coordination-Driven Self-Assembled Organoplatinum(II) Metallacycles. J. Am. Chem. Soc. 2020, 142, 5, 2601-2608.

18. Zhao Chen⁺, Jian-Hong Tang⁺, Wenzhuo Chen, Yao Xu, Heng Wang, Zhe Zhang, Hajar Sepehrpour, Gui-Juan Cheng, Xiaopeng Li, Pingshan Wang, Yue Sun,* and Peter J. Stang*, Temperature and Mechanical Force Responsive Self-Assembled Rhomboidal Metallacycle, Organometallics, 2019, 38, 4244-4249. 

17. Jian-Hong Tang⁺, Yueqi Li⁺, Qingqing Wu⁺, Songjun Hou, Zixiao Wang, Kun Tang, Yue Su, Hui Wang, Heng Wang, Xiaopeng Li, Jiannian Yao, Colin J. Lambert*, Nongjian Tao*, Yu-Wu Zhong* and Peter J. Stang*, Single-molecule level control of host-guest interactions in metallocycle-C₆₀ complexes, Nat. Commun., 2019, 10, 4599. (Editor’s highlights). 

16. Jian-Hong Tang⁺, Ruidong Ni⁺, Yan-Qin He⁺, Ryan T. Vanderlinden, Yanrong Li, Bingbing Shi, Zhong-Yu Li, Heng Wang,* Xiaopeng Li, Yue Sun,* Yu-Wu Zhong,* and Peter J. Stang*, Metal−Organic Pt(II) Hexagonal-Prism Macrocycles and Their Photophysical Properties, Inorg. Chem, 2019, 58, 13376-13381.

15. Bingbing Shi, Zhixuan Zhou, Ryan T. Vanderlinden, Jian-Hong Tang, Guocan, Yu*, Koushik Acharyya, Peter J. Stang*, Spontaneous Supramolecular Polymerization Driven by Discrete Platinum Metallacycle-Based Host–Guest Complexation, J. Am. Chem. Soc. 2019, 141, 11837-11841.

14. Bingbing Shi, Yuezhou Liu, Huangtianzhi Zhu, Ryan T. Vanderlinden, Liqing Shangguan, Ruidong Ni, Koushik Acharyya, Jian-Hong Tang, Zhixuan Zhou, Xiaopeng Li, Feihe Huang*, Peter J. Stang*, Spontaneous Formation of a Cross-Linked Supramolecular Polymer Both in the Solid State and in Solution, Driven by Platinum(II) Metallacycle-Based Host−Guest Interactions, J. Am. Chem. Soc. 2019, 141, 6494−6498.

13. Jiang-Yang Shao, Bin-Bin Cui, Jian-Hong Tang, Yu-Wu Zhong*, Resistive memory switching of transition-metal complexes controlled by ligand design, Coord. Chem. Rev. 2019, 393, 21−36.

12. Jian-Hong Tang⁺, Yue Sun⁺, Zhong-Liang Gong, Zhong-Yu Li, Zhixuan Zhou, Heng Wang, Xiaopeng Li, Manik Lal Saha*, Yu-Wu Zhong* and Peter J. Stang*, Temperature-Responsive Fluorescent Organoplatinum(II) Metallacycles, J. Am. Chem. Soc. 2018, 140, 7723-7729.

11. Jian-Hong Tang, Zhenfeng Cai, Dong Yan, Kun Tang, Jiang-Yang Shao, Chuanlang Zhan, Dong Wang, Yu-Wu Zhong*, Li-Jun Wan, Jiannian Yao, A Molecular Quadripod as a Noncovalent Interfacial Coupling Reagent for Forming Immobilized Coordination
Assemblies, J. Am. Chem. Soc. 2018, 140, 12337-12340.

10. Rui Li, Zhong-Liang Gong, Jian-Hong Tang, Meng-Jia Sun, Jiang-Yang Shao, Yu-Wu Zhong* and Jiannian Yao, Triarylamines with branched multi-pyridine groups: modulation of emission properties by structural variation, solvents, and tris(pentafluorophenyl)borane. Sci. China Chem. 2018, 61(5), 545-556.

9. Jian-Hong Tang, Tian-Ge Sun, Jiang-Yang Shao, Zhong-Liang Gong and Yu-Wu Zhong*, Resistive memory devices based on a triphenylamine-decorated non-precious cobalt(II) bis-terpyridine complex, Chem. Commun. 2017, 53, 11925-11928.

8. Jian-Hong Tang, Jiang-Yang Shao, Yan-Qin He, Si-Hai Wu, Jiannian Yao, Yu-Wu Zhong*, Transition from a Metal-Localized Mixed-Valence Compound to a Fully Delocalized and Bridge-Biased Electrophore in a Ruthenium-Amine-Ruthenium Tricenter System, Chem. Eur. J. 2016, 22(30), 10341-10345.

7. Jian-Hong Tang, Yan-Qin He, Jiang-Yang Shao, Zhong-Liang Gong, Yu-Wu Zhong*, Multistate Redox Switching and Near-Infrared Electrochromism Based on a Star-Shaped Triruthenium Complex with a Triarylamine Core, Sci. Rep. 2016, 6, 35253.

6. Jian-Hong Tang, Chang-Jiang Yao, Bin-Bin Cui and Yu-Wu Zhong*, Ruthenium-Amine Conjugated Organometallic Materials for Multistate Near-IR Electrochromism and Information Storage, Chem. Rec. 2016, 16(2), 754-767.

5. Bin-Bin Cui, Jian-Hong Tang, Yu-Wu Zhong*, Resistive Memory Materials Based on Transition-Metal Complexes, Acta Chim. Sinica 2016, 74(9), 726-733. 

4. Zhongliang Gong , Changjiang Yao , Jiangyang Shao , Haijing Nie , Jianhong Tang, Zhong Yuwu*, Redox-responsive cyclometalated ruthenium and osmium complexes, Sci. Sin. Chim. 2016, 46(10), 1093-1100. 

3. You-Ming Zhang, Fanyuan Meng, Jian-Hong Tang, Yafei Wang, Caifa You, Hua Tan, Yu Liu, Yu-Wu Zhong*, Shijian Su* and Weiguo Zhu*, Achieving near-infrared emission in platinum(II) complexes by using an extended donor–acceptor-type ligand, Dalton Trans. 2016, 45, 5071-5080. 

2. Bin-Bin Cui⁺, Jian-Hong Tang⁺, Jiannian Yao, and Yu-Wu Zhong*, A Molecular Platform for Multistate Near-Infrared Electrochromism and Flip-Flop, Flip-Flap-Flop, and Ternary Memory, Angew. Chem. Int. Ed. 2015, 54(32), 9192-9197.

1. Jian-Hong Tang, Si-Hai Wu, Jiang-Yang Shao, Hai-Jing Nie, Yu-Wu Zhong,* Ruthenium-Amine Electronic Coupling Bridged through Phen-1,3-diyl Versus Phen-1,4-diyl: Reverse of the Charge Transfer Direction, Organometallics 2013, 32(16), 4564-4570.