基本信息
刘宽庆  男  博导  中国科学院天津工业生物技术研究所
电子邮件: liukq@tib.cas.cn
通信地址: 天津空港经济区西七道32号
邮政编码: 300308

研究领域

  1. 微生物合成生物学
  2. 微生物代谢工程学
  3. 分子生物学和生物化学

教育背景

2009-08--2015-05   贝勒医学院   博士
2007-08--2009-07   宾夕法尼亚州立大学   硕士
2003-09--2007-07   中国农业大学   学士

工作经历

2021-12--现在,中国科学院天津工业生物技术研究所,研究员

2015-09--2021-11, 德克萨斯大学西南医学中心, 博士后


出版信息

   
发表论文
[1] Scarborough, Anna M, Flaherty, Juliana N, Hunter, Olga, V, Liu, Kuanqing, Kumar, Ashwani, Xing, Chao, Tu, Benjamin P, Conrad, Nicholas K. SAM homeostasis is regulated by CFIm-mediated splicing of MAT2A. ELIFE[J]. 2021, 10: https://doaj.org/article/ac2b0adbe78347f28a8d8a053ebe0d0d.
[2] Liu, Kuanqing, Santos, Daniel A, Hussmann, Jeffrey A, Wang, Yun, Sutter, Benjamin M, Weissman, Jonathan S, Tu, Benjamin P. Regulation of translation by methylation multiplicity of 18S rRNA. CELL REPORTS[J]. 2021, 34(10): 108825-108825, http://dx.doi.org/10.1016/j.celrep.2021.108825.
[3] Kuanqing Liu, Benjamin M Sutter, Benjamin P Tu. Autophagy sustains glutamate and aspartate synthesis in Saccharomyces cerevisiae during nitrogen starvation. NATURE COMMUNICATIONS[J]. 2021, 12(1): http://dx.doi.org/10.1038/s41467-020-20253-6.
[4] Anderson, Brent W, Liu, Kuanqing, Wolak, Christine, Dubiel, Katarzyna, She, Fukang, Satyshur, Kenneth A, Keck, James L, Wang, Jue D. Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction. ELIFE[J]. 2019, 8: https://doaj.org/article/a0342011588d4272a5a29fd9a4d5eaf5.
[5] Weiss, Cordelia A, Hoberg, Jakob A, Liu, Kuanqing, Tu, Benjamin P, Winkler, Wade C. Single-Cell Microscopy Reveals That Levels of Cyclic di-GMP Vary among Bacillus subtilis Subpopulations. JOURNAL OF BACTERIOLOGY[J]. 2019, 201(16): [6] Orr, Mona W, Weiss, Cordelia A, Severin, Geoffrey B, Turdiev, Husan, Kim, SooKyoung, Turdiev, Asan, Liu, Kuanqing, Tu, Benjamin P, Waters, Christopher M, Winkler, Wade C, Lee, Vincent T. A Subset of Exoribonucleases Serve as Degradative Enzymes for pGpG in c-di-GMP Signaling. JOURNAL OF BACTERIOLOGY[J]. 2018, 200(24): https://www.webofscience.com/wos/woscc/full-record/WOS:000451219500002.
[7] Pendleton, Kathryn E, Chen, Beibei, Liu, Kuanqing, Hunter, Olga V, Xie, Yang, Tu, Benjamin P, Conrad, Nicholas K. The U6 snRNA m(6)A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention. CELL[J]. 2017, 169(5): 824-+, http://dx.doi.org/10.1016/j.cell.2017.05.003.
[8] Li, Wenting, Bouveret, Emmanuelle, Zhang, Yan, Liu, Kuanqing, Wang, Jue D, Weisshaar, James C. Effects of amino acid starvation on RelA diffusive behavior in live Escherichia coli. MOLECULAR MICROBIOLOGY[J]. 2016, 99(3): 571-585, https://www.webofscience.com/wos/woscc/full-record/WOS:000369156200010.
[9] Liu, Kuanqing, Myers, Angela R, Pisithkul, Tippapha, Claas, Kathy R, Satyshur, Kenneth A, AmadorNoguez, Daniel, Keck, James L, Wang, Jue D. Molecular Mechanism and Evolution of Guanylate Kinase Regulation by (p)ppGpp. MOLECULAR CELL[J]. 2015, 57(4): 735-749, http://dx.doi.org/10.1016/j.molcel.2014.12.037.
[10] Gaca, Anthony O, Kudrin, Pavel, ColomerWinter, Cristina, Beljantseva, Jelena, Liu, Kuanqing, Anderson, Brent, Wang, Jue D, Rejman, Dominik, Potrykus, Katarzyna, Cashel, Michael, Hauryliuk, Vasili, Lemos, Jose A. From (p)ppGpp to (pp)pGpp: Characterization of Regulatory Effects of pGpp Synthesized by the Small Alarmone Synthetase of Enterococcus faecalis. JOURNAL OF BACTERIOLOGY[J]. 2015, 197(18): 2908-2919, https://www.webofscience.com/wos/woscc/full-record/WOS:000360712700002.
[11] Liu, Kuanqing, Bittner, Alycia N, Wang, Jue D. Diversity in (p)ppGpp metabolism and effectors. CURRENT OPINION IN MICROBIOLOGYnull. 2015, 24: 72-79, http://dx.doi.org/10.1016/j.mib.2015.01.012.
[12] Gaca, Anthony O, Kajfasz, Jessica K, Miller, James H, Liu, Kuanqing, Wang, Jue D, Abranches, Jacqueline, Lemos, Jose A. Basal Levels of (p)ppGpp in Enterococcus faecalis: the Magic beyond the Stringent Response. MBIO[J]. 2013, 4(5): https://www.webofscience.com/wos/woscc/full-record/WOS:000326881800027.
[13] Kriel, Allison, Bittner, Alycia N, Kim, Sok Ho, Liu, Kuanqing, Tehranchi, Ashley K, Zou, Winnie Y, Rendon, Samantha, Chen, Rui, Tu, Benjamin P, Wang, Jue D. Direct Regulation of GTP Homeostasis by (p)ppGpp: A Critical Component of Viability and Stress Resistance. MOLECULAR CELL[J]. 2012, 48(2): 231-241, http://dx.doi.org/10.1016/j.molcel.2012.08.009.
[14] Hartzell, Annette, Chen, Chun, Lewis, Carrie, Liu, Kuanqing, Reynolds, Stanley, Dudley, Edward G. Escherichia coli O157:H7 of Genotype Lineage-Specific Polymorphism Assay 211111 and Clade 8 Are Common Clinical Isolates Within Pennsylvania. FOODBORNE PATHOGENS AND DISEASE[J]. 2011, 8(7): 763-768, https://www.webofscience.com/wos/woscc/full-record/WOS:000292284800002.
[15] Liu, K, Knabel, S J, Dudley, E G. rhs Genes Are Potential Markers for Multilocus Sequence Typing of Escherichia coli O157:H7 Strains. APPLIED AND ENVIRONMENTAL MICROBIOLOGY[J]. 2009, 75(18): 5853-5862, https://www.webofscience.com/wos/woscc/full-record/WOS:000269608000014.
[16] 田洪涛, 万红兵, 刘宽庆, 山丽杰, 李雅乾, 袁耀武. 酸奶冻干发酵剂制备中保加利亚乳杆菌不同菌株特性的研究. 中国乳品工业[J]. 2006, 34(12): 4-6, [17] 郝彦玲, 朱本忠, 栾春光, 刘宽庆, 罗云波. 向日葵种子特异性启动子Ha ds10 G1的克隆及其功能验证. 农业生物技术学报[J]. 2006, 14(6): 922-925,