基本信息
王国坤 男 博导 中国科学院天津工业生物技术研究所
电子邮件： wanggk@tib.cas.cn
通信地址： 天津市空港经济区西七道32号
邮政编码：
电子邮件： wanggk@tib.cas.cn
通信地址： 天津市空港经济区西七道32号
邮政编码：
研究领域
合成生物学驱动的功能性营养资源车间制造
围绕蛋白质资源短缺和机体健康保障的重大需求，以发酵高质蛋白和功能性天然产物为解决方案，通过发展基因组编辑工具和高通量筛选方法，结合大数据产生与分析，破译表型和基因型之间的联系，解构复杂生物代谢网络并进行系统重编程，定制高版本酵母菌株高效转化可再生原料合成功能性营养资源。
招生信息
招生专业
071005-微生物学
081703-生物化工
071010-生物化学与分子生物学
081703-生物化工
071010-生物化学与分子生物学
招生方向
基因组定向进化
酵母代谢工程
酵母代谢工程
教育背景
2012-09--2016-01 中国科学院大学 博士学位
工作经历
2022年10月-今，中国科学院天津工业生物技术研究所，研究员，博士研究生、硕士研究生指导教师
2021年6月-2022年9月，中国科学院天津工业生物技术研究所，副研究员，博士研究生、硕士研究生指导教师
2018年6月-2021年5月，丹麦科技大学，博士研究生、硕士研究生、本科生指导教师
2018年3月-2021年5月，丹麦科技大学，博士后研究员
2016年1月-2018年1月，查尔姆斯理工大学，博士后研究员
工作简历
2018-03~2021-05,丹麦科技大学, 博士后研究员
2016-01~2018-01,查尔姆斯理工大学, 博士后研究员
2016-01~2018-01,查尔姆斯理工大学, 博士后研究员
社会兼职
2025-02-19-今,第四届全国饲料评审委员会委员, 委员
2024-01-01-今,The Innovation期刊青年编辑, 青年编辑
2022-05-31-今,BMC Biotechnol.期刊编委, 编委
2024-01-01-今,The Innovation期刊青年编辑, 青年编辑
2022-05-31-今,BMC Biotechnol.期刊编委, 编委
专利与奖励
专利成果
[1] 张东远, 王国坤, 张运鹏. 利用重组载体在丝状真菌中筛选外源基因的方法. CN: CN105463009A, 2016-04-06.
[2] 宗志友, 高乐, 王国坤, 李晨, 崔超, 陈树林. 一种β-葡萄糖苷酶和β-葡萄糖苷酶突变体及应用. CN: CN104560917A, 2015-04-29.
[3] 宗志友, 宗志友, 高乐, 王国坤, 李晨, 崔超, 陈树林. 一种β-葡萄糖苷酶和β-葡萄糖苷酶突变体及应用. CN: CN104531637A, 2015-04-22.
[2] 宗志友, 高乐, 王国坤, 李晨, 崔超, 陈树林. 一种β-葡萄糖苷酶和β-葡萄糖苷酶突变体及应用. CN: CN104560917A, 2015-04-29.
[3] 宗志友, 宗志友, 高乐, 王国坤, 李晨, 崔超, 陈树林. 一种β-葡萄糖苷酶和β-葡萄糖苷酶突变体及应用. CN: CN104531637A, 2015-04-22.
出版信息
发表论文
[1] Rong, Weihe, Lin, Liangcai, Wang, Guokun. Nitroplasts suggest the creation of artificial nitrogen-fixing eukaryotes. TRENDS IN BIOTECHNOLOGY. 2024, 第 3 作者 通讯作者 42(8): 946-948, http://dx.doi.org/10.1016/j.tibtech.2024.06.002.
[2] Liu, Lu, Rong, Weihe, Du, Xiang, Yuan, Qianqian, Xu, Zhaoyu, Yu, Chang, Lu, Hongzhong, Wang, Yanfei, Zhu, Yan, Liu, Zhijia, Wang, Guokun. Integrating Experimental and Computational Analyses of Yeast Protein Profiles for Optimizing the Production of High-Quality Microbial Proteins. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY. 2024, 第 11 作者 通讯作者 http://dx.doi.org/10.1007/s12010-024-04995-3.
[3] 王国坤, 蔺玉萍, 王钦宏, 吴信, 印遇龙, 马延和. 微生物蛋白制造的发展趋势与挑战. 科学通报[J]. 2023, 第 1 作者 通讯作者
[4] 蔡韬, 刘玉万, 朱蕾蕾, 苏浩, 王钰, 王国坤, 张玲玲, 朱之光, 盛翔, 毕昌昊, 马红武, 田朝光, 张学礼, 吴洽庆, 孙媛霞, 江会锋, 马延和, , , , , , , , , , , , , , , , , . 二氧化碳人工生物转化. 生物工程学报[J]. 2022, 第 6 作者38(11): 4101-4114, https://cjb.ijournals.cn/cjbcn/article/abstract/gc22114101?st=article_issue.
[5] Guokun Wang, Xin Wu, Yulong Yin. Synthetic biology-driven customization of functional feed resources. Trends in Biotechnology[J]. 2022, 第 1 作者 通讯作者 https://doi.org/10.1016/j.tibtech.2022.03.002.
[6] Steven A van der Hoek, Matej Rusnák, Guokun Wang, Lyubomir DimitrovStanchev, Luanade Fátima Alves, Mathew M. Jessop-Fabre, KalaivaniParamasivan, Irene HjorthJacobsen, Nikolaus Sonnenschein, José L.Martínez, Behrooz Darbani, Douglas B.Kell, IrinaBorodina. Engineering precursor supply for the high-level production of ergothioneine in Saccharomyces cerevisiae. Metabolic Engineering[J]. 2022, 第 3 作者https://doi.org/10.1016/j.ymben.2022.01.012.
[7] Wang, Guokun, Tavares, Aline, Schmitz, Simone, Franca, Lucas, Almeida, Hugo, Cavalheiro, Joao, Carolas, Ana, Ozmerih, Suleyman, Blank, Lars M, Ferreira, Bruno S, Borodina, Irina. An integrated yeast-based process for cis,cis-muconic acid production. BIOTECHNOLOGY AND BIOENGINEERING[J]. 2022, 第 1 作者119(2): 376-387, http://dx.doi.org/10.1002/bit.27992.
[8] Wang, Guokun, MollerHansen, Iben, Babaei, Mahsa, DAmbrosio, Vasil, Christensen, Hanne Bjerre, Darbani, Behrooz, Jensen, Michael Krogh, Borodina, Irina. Transportome-wide engineering of Saccharomyces cerevisiae. METABOLIC ENGINEERING[J]. 2021, 第 1 作者64: 52-63, http://dx.doi.org/10.1016/j.ymben.2021.01.007.
[9] Wang, Guokun, Kell, Douglas B, Borodina, Irina. Harnessing the yeast Saccharomyces cerevisiae for the production of fungal secondary metabolites. ESSAYS IN BIOCHEMISTRY[J]. 2021, 第 1 作者 通讯作者 65(2): 277-291, http://dx.doi.org/10.1042/EBC20200137.
[10] Wang, Guokun, Mattis Olofsson-Dolk, Frederik Gleerup Hansson, StefanoDonat, XiaolinLi, HongChang, Jian Cheng, Jonathan Dahli, Irina Borodina. Engineering Yeast Yarrowia lipolytica for Methanol Assimilation. ACS SYNTHETIC BIOLOGY[J]. 2021, 第 1 作者 通讯作者
[11] Kosiorowska, Katarzyna E, Polomska, Xymena, Wang, Guokun, Borodina, Irina, Mironczuk, Aleksandra M. Efficient biodegradation of aliphatic polyester by genetically engineered strains of the yeast Yarrowia lipolytica. INTERNATIONAL BIODETERIORATION & BIODEGRADATION[J]. 2021, 第 3 作者161: http://dx.doi.org/10.1016/j.ibiod.2021.105232.
[12] SaezSaez, Javier, Wang, Guokun, Marella, Eko Roy, Sudarsan, Suresh, Pastor, Marc Cernuda, Borodina, Irina. Engineering the oleaginous yeast Yarrowia lipolytica for high-level resveratrol production. METABOLIC ENGINEERING[J]. 2020, 第 2 作者 通讯作者 62: 51-61, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672257/.
[13] Marella, Eko Roy, Dahlin, Jonathan, Dam, Marie Inger, ter Horst, Jolanda, Christensen, Hanne Bjerre, Sudarsan, Suresh, Wang, Guokun, Holkenbrink, Carina, Borodina, Irina. A single-host fermentation process for the production of flavor lactones from non-hydroxylated fatty acids. METABOLIC ENGINEERING[J]. 2020, 第 7 作者61: 427-436, http://dx.doi.org/10.1016/j.ymben.2019.08.009.
[14] Wang, Guokun, Ozmerih, Suleyman, Guerreiro, Rogerio, Meireles, Ana C, Carolas, Ana, Milne, Nicholas, Jensen, Michael K, Ferreira, Bruno S, Borodina, Irina. Improvement of cis,cis-Muconic Acid Production in Saccharomyces cerevisiae through Biosensor-Aided Genome Engineering. ACS SYNTHETIC BIOLOGY[J]. 2020, 第 1 作者9(3): 634-646, http://dx.doi.org/10.1021/acssynbio.9b00477.
[15] Rzechonek, Dorota A, Szczepanczyk, Mateusz, Wang, Guokun, Borodina, Irina, Miroriczuk, Aleksandra M. HOG-Independent Osmoprotection by Erythritol in Yeast Yarrowia lipolytica. GENES[J]. 2020, 第 3 作者11(12): http://dx.doi.org/10.3390/genes11121424.
[16] Wang, Guokun, Bjork, Sara M, Huang, Mingtao, Liu, Quanli, Campbell, Kate, Nielsen, Jens, Joensson, Haakan N, Petranovic, Dina. RNAi expression tuning, microfluidic screening, and genome recombineering for improved protein production in Saccharomyces cerevisiae. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2019, 第 1 作者116(19): 9324-9332, http://dx.doi.org/10.1073/pnas.1820561116.
[17] Dahlin, Jonathan, Holkenbrink, Carina, Morella, Eko Roy, Wang, Guokun, Liebal, Ulf, Lieven, Christian, Weber, Dieter, McCloskey, Douglas, Ebert, Birgitta E, Herrgard, Markus J, Blank, Lars Mathias, Borodina, Irina. Multi-Omics Analysis of Fatty Alcohol Production in Engineered Yeasts Saccharomyces cerevisiae and Yarrowia lipolytica. FRONTIERS IN GENETICS[J]. 2019, 第 4 作者10: https://doaj.org/article/d7a1629f41254da3b65667bd3d89fa8c.
[18] Huang, Mingtao, Wang, Guokun, Qin, Jiufu, Petranovic, Dina, Nielsen, Jens. Engineering the protein secretory pathway of Saccharomyces cerevisiae enables improved protein production. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2018, 第 2 作者115(47): E11025-E11032, http://dx.doi.org/10.1073/pnas.1809921115.
[19] Wang, Guokun, Jia, Wendi, Chen, Na, Zhang, Ke, Wang, Lixian, Lv, Pin, He, Ronglin, Wang, Min, Zhang, Dongyuan. A GFP-fusion coupling FACS platform for advancing the metabolic engineering of filamentous fungi. BIOTECHNOLOGY FOR BIOFUELS[J]. 2018, 第 1 作者11(1): https://doaj.org/article/349a278e9e614f0a9f4c715cb7504ba8.
[20] Wang, Guokun, Huang, Mingtao, Nielsen, Jens. Exploring the potential of Saccharomyces cerevisiae for biopharmaceutical protein production. CURRENT OPINION IN BIOTECHNOLOGY. 2017, 第 1 作者48: 77-84, http://dx.doi.org/10.1016/j.copbio.2017.03.017.
[21] Wang, Guokun, Xiong, Xiaochao, Ghogare, Rishikesh, Wang, Pengdong, Meng, Yonghong, Chen, Shulin. Exploring fatty alcohol-producing capability of Yarrowia lipolytica. BIOTECHNOLOGY FOR BIOFUELS[J]. 2016, 第 1 作者9(1): http://dx.doi.org/10.1186/s13068-016-0512-3.
[22] Wang, Guokun, Wang, Haijun, Xiong, Xiaochao, Chen, Shulin, Zhang, Dongyuan. Mitochondria thioredoxin's backup role in oxidative stress resistance in Trichoderma reesei. MICROBIOLOGICAL RESEARCH[J]. 2015, 第 1 作者171: 32-38, http://dx.doi.org/10.1016/j.micres.2015.01.005.
[23] Wang, Guokun, Lv, Pin, He, Ronglin, Wang, Haijun, Wang, Lixian, Zhang, Dongyuan, Chen, Shulin. Protein disulfide isomerase homolog TrPDI2 contributing to cellobiohydrolase production in Trichoderma reesei. ENZYME AND MICROBIAL TECHNOLOGY[J]. 2015, 第 1 作者77: 21-28, http://dx.doi.org/10.1016/j.enzmictec.2015.05.004.
[24] Wang, Guokun, Zhang, Dongyuan, Chen, Shulin. Effect of earlier unfolded protein response and efficient protein disposal system on cellulase production in Rut C30. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY[J]. 2014, 第 1 作者30(10): 2587-2595, http://124.16.173.210/handle/834782/1330.
[25] Feng, Yanan, Zhang, Meng, Guo, Qifang, Wang, Guokun, Gong, Jiangfeng, Xu, Ying, Wang, Wei. Manipulation of monoubiquitin improves chilling tolerance in transgenic tobacco (Nicotiana tabacum). PLANT PHYSIOLOGY AND BIOCHEMISTRY[J]. 2014, 第 4 作者75: 138-144, http://dx.doi.org/10.1016/j.plaphy.2013.11.003.
[26] 张粲, 高乐, 赫荣琳, 王国坤, 于俊杰, 武改红, 张东远. 桧状青霉原生质体制备和再生的研究. 基因组学与应用生物学[J]. 2014, 第 4 作者33(1): 57-62, http://lib.cqvip.com/Qikan/Article/Detail?id=50283101.
[27] Tian, Fengxia, Gong, Jiangfeng, Zhang, Jin, Feng, Yanan, Wang, Guokun, Guo, Qifang, Wang, Wei. Overexpression of monoubiquitin improves photosynthesis in transgenic tobacco plants following high temperature stress. PLANT SCIENCE[J]. 2014, 第 5 作者226: 92-100, http://dx.doi.org/10.1016/j.plantsci.2014.03.006.
[28] Tian, Fengxia, Gong, Jiangfeng, Zhang, Jin, Zhang, Meng, Wang, Guokun, Li, Aixiu, Wang, Wei. Enhanced stability of thylakoid membrane proteins and antioxidant competence contribute to drought stress resistance in the tasg1 wheat stay-green mutant. JOURNAL OF EXPERIMENTAL BOTANY[J]. 2013, 第 5 作者64(6): 1509-1520, http://dx.doi.org/10.1093/jxb/ert004.
[29] Tian, F X, Gong, J F, Wang, G P, Wang, G K, Fan, Z Y, Wang, W. Improved drought resistance in a wheat stay-green mutant tasg1 under field conditions. BIOLOGIA PLANTARUM[J]. 2012, 56(3): 509-515, http://dx.doi.org/10.1007/s10535-012-0049-7.
[30] Wang, GuoKun, Zhang, Meng, Gong, JiangFeng, Guo, QiFang, Feng, YaNan, Wang, Wei. Increased gibberellin contents contribute to accelerated growth and development of transgenic tobacco overexpressing a wheat ubiquitin gene. PLANT CELL REPORTS[J]. 2012, 第 1 作者31(12): 2215-2227, https://www.webofscience.com/wos/woscc/full-record/WOS:000310951600008.
[31] Hui, Zhen, Tian, FengXia, Wang, Guokun, Wang, GuiPing, Wang, Wei. The antioxidative defense system is involved in the delayed senescence in a wheat mutant tasg1. PLANT CELL REPORTS[J]. 2012, 第 3 作者31(6): 1073-1084, http://dx.doi.org/10.1007/s00299-012-1226-z.
[32] 王国坤, 田风霞, 宫江峰, 王玮. 泛素/26S蛋白酶体系统介导的细胞程序化死亡. 生命科学[J]. 2011, 第 1 作者23(1): 26-31, http://lib.cqvip.com/Qikan/Article/Detail?id=36775821.
[2] Liu, Lu, Rong, Weihe, Du, Xiang, Yuan, Qianqian, Xu, Zhaoyu, Yu, Chang, Lu, Hongzhong, Wang, Yanfei, Zhu, Yan, Liu, Zhijia, Wang, Guokun. Integrating Experimental and Computational Analyses of Yeast Protein Profiles for Optimizing the Production of High-Quality Microbial Proteins. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY. 2024, 第 11 作者 通讯作者 http://dx.doi.org/10.1007/s12010-024-04995-3.
[3] 王国坤, 蔺玉萍, 王钦宏, 吴信, 印遇龙, 马延和. 微生物蛋白制造的发展趋势与挑战. 科学通报[J]. 2023, 第 1 作者 通讯作者
[4] 蔡韬, 刘玉万, 朱蕾蕾, 苏浩, 王钰, 王国坤, 张玲玲, 朱之光, 盛翔, 毕昌昊, 马红武, 田朝光, 张学礼, 吴洽庆, 孙媛霞, 江会锋, 马延和, , , , , , , , , , , , , , , , , . 二氧化碳人工生物转化. 生物工程学报[J]. 2022, 第 6 作者38(11): 4101-4114, https://cjb.ijournals.cn/cjbcn/article/abstract/gc22114101?st=article_issue.
[5] Guokun Wang, Xin Wu, Yulong Yin. Synthetic biology-driven customization of functional feed resources. Trends in Biotechnology[J]. 2022, 第 1 作者 通讯作者 https://doi.org/10.1016/j.tibtech.2022.03.002.
[6] Steven A van der Hoek, Matej Rusnák, Guokun Wang, Lyubomir DimitrovStanchev, Luanade Fátima Alves, Mathew M. Jessop-Fabre, KalaivaniParamasivan, Irene HjorthJacobsen, Nikolaus Sonnenschein, José L.Martínez, Behrooz Darbani, Douglas B.Kell, IrinaBorodina. Engineering precursor supply for the high-level production of ergothioneine in Saccharomyces cerevisiae. Metabolic Engineering[J]. 2022, 第 3 作者https://doi.org/10.1016/j.ymben.2022.01.012.
[7] Wang, Guokun, Tavares, Aline, Schmitz, Simone, Franca, Lucas, Almeida, Hugo, Cavalheiro, Joao, Carolas, Ana, Ozmerih, Suleyman, Blank, Lars M, Ferreira, Bruno S, Borodina, Irina. An integrated yeast-based process for cis,cis-muconic acid production. BIOTECHNOLOGY AND BIOENGINEERING[J]. 2022, 第 1 作者119(2): 376-387, http://dx.doi.org/10.1002/bit.27992.
[8] Wang, Guokun, MollerHansen, Iben, Babaei, Mahsa, DAmbrosio, Vasil, Christensen, Hanne Bjerre, Darbani, Behrooz, Jensen, Michael Krogh, Borodina, Irina. Transportome-wide engineering of Saccharomyces cerevisiae. METABOLIC ENGINEERING[J]. 2021, 第 1 作者64: 52-63, http://dx.doi.org/10.1016/j.ymben.2021.01.007.
[9] Wang, Guokun, Kell, Douglas B, Borodina, Irina. Harnessing the yeast Saccharomyces cerevisiae for the production of fungal secondary metabolites. ESSAYS IN BIOCHEMISTRY[J]. 2021, 第 1 作者 通讯作者 65(2): 277-291, http://dx.doi.org/10.1042/EBC20200137.
[10] Wang, Guokun, Mattis Olofsson-Dolk, Frederik Gleerup Hansson, StefanoDonat, XiaolinLi, HongChang, Jian Cheng, Jonathan Dahli, Irina Borodina. Engineering Yeast Yarrowia lipolytica for Methanol Assimilation. ACS SYNTHETIC BIOLOGY[J]. 2021, 第 1 作者 通讯作者
[11] Kosiorowska, Katarzyna E, Polomska, Xymena, Wang, Guokun, Borodina, Irina, Mironczuk, Aleksandra M. Efficient biodegradation of aliphatic polyester by genetically engineered strains of the yeast Yarrowia lipolytica. INTERNATIONAL BIODETERIORATION & BIODEGRADATION[J]. 2021, 第 3 作者161: http://dx.doi.org/10.1016/j.ibiod.2021.105232.
[12] SaezSaez, Javier, Wang, Guokun, Marella, Eko Roy, Sudarsan, Suresh, Pastor, Marc Cernuda, Borodina, Irina. Engineering the oleaginous yeast Yarrowia lipolytica for high-level resveratrol production. METABOLIC ENGINEERING[J]. 2020, 第 2 作者 通讯作者 62: 51-61, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672257/.
[13] Marella, Eko Roy, Dahlin, Jonathan, Dam, Marie Inger, ter Horst, Jolanda, Christensen, Hanne Bjerre, Sudarsan, Suresh, Wang, Guokun, Holkenbrink, Carina, Borodina, Irina. A single-host fermentation process for the production of flavor lactones from non-hydroxylated fatty acids. METABOLIC ENGINEERING[J]. 2020, 第 7 作者61: 427-436, http://dx.doi.org/10.1016/j.ymben.2019.08.009.
[14] Wang, Guokun, Ozmerih, Suleyman, Guerreiro, Rogerio, Meireles, Ana C, Carolas, Ana, Milne, Nicholas, Jensen, Michael K, Ferreira, Bruno S, Borodina, Irina. Improvement of cis,cis-Muconic Acid Production in Saccharomyces cerevisiae through Biosensor-Aided Genome Engineering. ACS SYNTHETIC BIOLOGY[J]. 2020, 第 1 作者9(3): 634-646, http://dx.doi.org/10.1021/acssynbio.9b00477.
[15] Rzechonek, Dorota A, Szczepanczyk, Mateusz, Wang, Guokun, Borodina, Irina, Miroriczuk, Aleksandra M. HOG-Independent Osmoprotection by Erythritol in Yeast Yarrowia lipolytica. GENES[J]. 2020, 第 3 作者11(12): http://dx.doi.org/10.3390/genes11121424.
[16] Wang, Guokun, Bjork, Sara M, Huang, Mingtao, Liu, Quanli, Campbell, Kate, Nielsen, Jens, Joensson, Haakan N, Petranovic, Dina. RNAi expression tuning, microfluidic screening, and genome recombineering for improved protein production in Saccharomyces cerevisiae. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2019, 第 1 作者116(19): 9324-9332, http://dx.doi.org/10.1073/pnas.1820561116.
[17] Dahlin, Jonathan, Holkenbrink, Carina, Morella, Eko Roy, Wang, Guokun, Liebal, Ulf, Lieven, Christian, Weber, Dieter, McCloskey, Douglas, Ebert, Birgitta E, Herrgard, Markus J, Blank, Lars Mathias, Borodina, Irina. Multi-Omics Analysis of Fatty Alcohol Production in Engineered Yeasts Saccharomyces cerevisiae and Yarrowia lipolytica. FRONTIERS IN GENETICS[J]. 2019, 第 4 作者10: https://doaj.org/article/d7a1629f41254da3b65667bd3d89fa8c.
[18] Huang, Mingtao, Wang, Guokun, Qin, Jiufu, Petranovic, Dina, Nielsen, Jens. Engineering the protein secretory pathway of Saccharomyces cerevisiae enables improved protein production. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2018, 第 2 作者115(47): E11025-E11032, http://dx.doi.org/10.1073/pnas.1809921115.
[19] Wang, Guokun, Jia, Wendi, Chen, Na, Zhang, Ke, Wang, Lixian, Lv, Pin, He, Ronglin, Wang, Min, Zhang, Dongyuan. A GFP-fusion coupling FACS platform for advancing the metabolic engineering of filamentous fungi. BIOTECHNOLOGY FOR BIOFUELS[J]. 2018, 第 1 作者11(1): https://doaj.org/article/349a278e9e614f0a9f4c715cb7504ba8.
[20] Wang, Guokun, Huang, Mingtao, Nielsen, Jens. Exploring the potential of Saccharomyces cerevisiae for biopharmaceutical protein production. CURRENT OPINION IN BIOTECHNOLOGY. 2017, 第 1 作者48: 77-84, http://dx.doi.org/10.1016/j.copbio.2017.03.017.
[21] Wang, Guokun, Xiong, Xiaochao, Ghogare, Rishikesh, Wang, Pengdong, Meng, Yonghong, Chen, Shulin. Exploring fatty alcohol-producing capability of Yarrowia lipolytica. BIOTECHNOLOGY FOR BIOFUELS[J]. 2016, 第 1 作者9(1): http://dx.doi.org/10.1186/s13068-016-0512-3.
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发表著作
（1） Engineering Biology for Microbial Biosynthesis of Plant-Derived Bioactive Compounds, Elsevier, 2024-03, 第 其他 作者
科研活动
科研项目
（ 1 ） 饲用蛋白高效表达底盘细胞创制, 负责人, 中国科学院计划, 2023-10--2026-09
（ 2 ） 酵母细胞工厂高耐受植物多酚的分子基础探究与再造, 负责人, 国家任务, 2023-01--2026-12
（ 3 ） 功能性饲用蛋白合成生物学, 负责人, 国家任务, 2023-01--2025-12
（ 4 ） 功能性饲用蛋白合成生物学（国家引才青年项目配套）, 负责人, 中国科学院计划, 2023-01--2025-12
（ 5 ） 甲基营养型酵母的设计构建及生产高质单细胞蛋白应用, 负责人, 地方任务, 2021-06--2024-05
（ 2 ） 酵母细胞工厂高耐受植物多酚的分子基础探究与再造, 负责人, 国家任务, 2023-01--2026-12
（ 3 ） 功能性饲用蛋白合成生物学, 负责人, 国家任务, 2023-01--2025-12
（ 4 ） 功能性饲用蛋白合成生物学（国家引才青年项目配套）, 负责人, 中国科学院计划, 2023-01--2025-12
（ 5 ） 甲基营养型酵母的设计构建及生产高质单细胞蛋白应用, 负责人, 地方任务, 2021-06--2024-05
参与会议
（1）合成生物学推动绿色养殖发展 第六届农业生态前沿青年论坛 2021-10-16
（2）开发酵母细胞工厂生产蛋白、营养品及化工品 2021年中国生物工程学会第五届青年科技论坛 2021-07-04
（3）Exploring the potential of yeast cell factories for the production of protein, nutraceutical and chemical 2021-05-19
（4）Exploring the potential of yeast cell factories for the production of protein, nutraceutical and chemical 三峡大学第一届合成生物学前沿论坛 2020-10-18
（2）开发酵母细胞工厂生产蛋白、营养品及化工品 2021年中国生物工程学会第五届青年科技论坛 2021-07-04
（3）Exploring the potential of yeast cell factories for the production of protein, nutraceutical and chemical 2021-05-19
（4）Exploring the potential of yeast cell factories for the production of protein, nutraceutical and chemical 三峡大学第一届合成生物学前沿论坛 2020-10-18
指导学生
现指导学生
周弘艺 硕士研究生 086000-生物与医药
史智慧 博士研究生 071010-生物化学与分子生物学
刘松奇 硕士研究生 086000-生物与医药