070303-有机化学

有机小分子催化，不对称催化，可见光催化

2013-09--2016-07   中国科学院化学研究所   博士学位
2010-09--2013-07   中国科学院昆明植物研究所   硕士学位
2006-09--2010-07   云南农业大学   学士学位

   

2016-07~现在, 中国科学院化学研究所, 助理研究员/副研究员
2013-09~2016-07,中国科学院化学研究所, 博士学位
2010-09~2013-07,中国科学院昆明植物研究所, 硕士学位
2006-09~2010-07,云南农业大学, 学士学位

有机化学
有机化学习题课
前沿化学实验
有机化学习题课-2

   

（1） 化学所优秀职工, 研究所（学校）, 2019
（2） 青年科学奖特别优秀奖, , 研究所（学校）, 2019

（ 1 ） 一种制备手性α-酰氧基-β，γ-不饱和酯类化合物的方法, 2022, 第 2 作者, 专利号: CN115477583A

（ 2 ） 一种手性胺类化合物及其制备方法, 2022, 第 3 作者, 专利号: CN115340514A

（ 3 ） 一种氮杂*酮化合物及其制备方法, 2018, 第 2 作者, 专利号: CN108623610A

   

（1） Iminoacylation of Alkenes via Photoredox N-Heterocyclic Carbene Catalysis, ORGANIC LETTERS, 2023, 通讯作者
（2） Distal p-benzylic deuteration via N-heterocyclic carbene catalyzed ring opening of p-cyclopropylbenzaldehydes, ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 第 3 作者
（3） Enantioselective N-Heterocyclic Carbene Catalyzed alpha-Oxidative Coupling of Enals with Carboxylic Acids Using an Iodine(III) Reagent, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 通讯作者
（4） Bifunctional NHC-Catalyzed Remote Enantioselective Mannich-type Reaction of 5-(Chloromethyl)furfural via Trienolate Intermediates, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 通讯作者
（5） Biomimetic asymmetric catalysis, Biomimetic asymmetric catalysis, SCIENCE CHINA-CHEMISTRY, 2023, 第 3 作者
（6） Cooperative N-Heterocyclic Carbene/Nickel-Catalyzed Hydroacylation of 1,3-Dienes with Aldehydes in Water, ACS CATALYSIS, 2022, 第 3 作者
（7） ε-Benzylation via Cooperative Photoredox and N-Heterocyclic Carbene Catalysis, JOURNAL OF ORGANIC CHEMISTRY, 2022, 通讯作者
（8） Photoredox cooperative N-heterocyclic carbene/palladium-catalysed alkylacylation of alkenes, NATURE COMMUNICATIONS, 2022, 第 4 作者
（9） NHC/Copper-Cocatalyzed 4+3 Annulations of Salicylaldehydes with Aziridines for the Synthesis of 1,4-Benzoxazepinones, ORGANIC LETTERS, 2020, 第 2 作者
（10） N-Heterocyclic Carbene Catalyzed Photooxidation: Intramolecular Cross Dehydrogenative Coupling of Tetrahydroisoquinoline-Tethered Aldehydes, ADVANCED SYNTHESIS & CATALYSIS, 2020, 第 1 作者
（11） Bifunctional N-Heterocyclic Carbenes Derived from L-Pyroglutamic Acid and Their Applications in Enantioselective Organocatalysis, ACCOUNTS OF CHEMICAL RESEARCH, 2020, 第 2 作者
（12） N-Heterocyclic carbene/photo-cocatalyzed oxidative Smiles rearrangement: synthesis of aryl salicylates from O-aryl salicylaldehydes, CHEMICAL COMMUNICATIONS, 2020, 第 3 作者
（13） Bifunctional N-heterocyclic carbene catalyzed 3+4 annulation of enals with azadienes: enantioselective synthesis of benzofuroazepinones, ORGANICCHEMISTRYFRONTIERS, 2019, 第 2 作者
（14） Visible-Light-Driven N-Heterocyclic Carbene Catalyzed gamma- and epsilon-Alkylation with Alkyl Radicals, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 通讯作者
（15） Visible-Light-Promoted Oxo-difluoroalkylation of Alkenes with DMSO as the Oxidant, JOURNAL OF ORGANIC CHEMISTRY, 2019, 第 2 作者
（16） N-Heterocyclic Carbene Catalyzed Synthesis of Dihydroxybenzophenones from -Methylenals and Aurones, CHEMISTRY-A EUROPEAN JOURNAL, 2019, 第 3 作者
（17） (Dynamic) Kinetic Resolution of Enamines/Imines: Enantioselective N-Heterocyclic Carbene Catalyzed 3+3 Annulation of Bromoenals and Enamines/Imines, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 第 2 作者
（18） Oxidative N-Heterocyclic Carbene-Catalyzed 8+2 Annulation of Tropone and Aldehydes: Synthesis of Cycloheptatriene-Fused Furanones, ADVANCED SYNTHESIS & CATALYSIS, 2019, 第 2 作者
（19） Visible light mediated oxidative lactonization of 2-methyl-1,1 '-biaryls for the synthesis of benzocoumarins, ORGANIC & BIOMOLECULAR CHEMISTRY, 2019, 第 2 作者
（20） Enantioselective n-heterocyclic carbene-catalyzed synthesis of spirocyclic oxindole-benzofuroazepinones, JOURNAL OF ORGANIC CHEMISTRY, 2018, 第 1 作者
（21） Switchable Decarboxylative Heck-Type Reaction and Oxo-alkylation of Styrenes with N-Hydroxyphthalimide Esters under Photocatalysis, ORGANIC LETTERS, 2018, 通讯作者
（22） Enantioselective Synthesis of Cyclic alpha-Aminophosphonates through N-Heterocyclic Carbene-Catalyzed 4+2 Annulation of Enals with alpha-Iminophosphonates, ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2018, 第 2 作者
（23） N-Heterocyclic Carbene-Catalyzed Annulation of alpha-Chloroaldehydes with gamma-/delta-Amino-alpha,beta-Unsaturated Ketones: Enantioselective Synthesis of Pyrrolidones and Piperidones, CHEMISTRY-A EUROPEAN JOURNAL, 2018, 第 4 作者
（24） 4+2 and 3+2 Annulations of alpha-Chloroaldehydes and Dithioesters: Synthesis of 1,4-Oxathiin-2(3H)-ones and 1,3-Oxathioles, ADVANCED SYNTHESIS & CATALYSIS, 2017, 第 2 作者
（25） Formylation or methylation: what determines the chemoselectivity of the reaction of amine, CO2, and hydrosilane catalyzed by 1,3,2-diazaphospholene?, CHEMICAL SCIENCE, 2017, 第 2 作者
（26） N-Heterocyclic Carbene-Catalyzed Synthesis of Multi-Substituted Benzenes from Enals and alpha-Cyano-beta-methylenones, ADVANCED SYNTHESIS & CATALYSIS, 2016, 第 2 作者
（27） N-Heterocyclic carbene-catalyzed 4+2 annulation of alpha,beta-unsaturated carboxylic acids: enantioselective synthesis of dihydropyridinones and spirocyclic oxindolodihydropyridinones, ORGANIC CHEMISTRY FRONTIERS, 2016, 第 4 作者
（28） Bronsted Acid-Catalyzed Synthesis of N-Arylindoles from 2-Vinylanilines and Quinones, CHEMISTRY-AN ASIAN JOURNAL, 2016, 第 2 作者
（29） N-Heterocyclic carbene-catalyzed 3+3 cyclocondensation of bromoenals with aldimines: highly enantioselective synthesis of dihydropyridinones, CHEMICAL COMMUNICATIONS, 2015, 通讯作者
（30） N-Heterocyclic Carbene Catalyzed Generation and 4+2 Annulation of Unsubstituted Dienolate - Enantioselective Synthesis of Spirocyclic Oxindolodihydropyranones, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2015, 第 3 作者
（31） Bifunctional N-Heterocyclic Carbene Catalyzed 3+4 Annulation of Enals and Aurones, CHEMISTRY-A EUROPEAN JOURNAL, 2015, 第 2 作者
（32） N-Heterocyclic carbene-catalyzed 2+3 cyclocondensation of alpha-chloroaldehydes with azomethine imines, CHEMICAL COMMUNICATIONS, 2015, 第 1 作者
（33） Structure and bioactivity of triterpenoids from the stems of Schisandra sphenanthera, ARCHIVES OF PHARMACAL RESEARCH, 2014, 第 8 作者
（34） Bifunctional N-Heterocyclic Carbene-Catalyzed Highly Enantioselective Synthesis of Spirocyclic Oxindolo-beta-lactams, ORGANIC LETTERS, 2014, 第 2 作者
（35） N-Heterocyclic Carbene Catalyzed Cyclocondensation of alpha,beta-Unsaturated Carboxylic Acids: Enantioselective Synthesis of Pyrrolidinone and Dihydropyridinone Derivatives, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2014, 第 2 作者
（36） Nortriterpenoids from Schisandra chinensis and their absolute configurational assignments by electronic circular dichroism study, TETRAHEDRON, 2014, 第 6 作者
（37） New Lignans from the Leaves and Stems of Schisandra chinensis and Their Anti-HIV-1 Activities, CHINESE JOURNAL OF CHEMISTRY, 2014, 第 7 作者
（38） Six new lignans from the leaves and stems of Schisandra sphenanthera, FITOTERAPIA, 2013, 第 6 作者
（39） Four new lignans from the leaves and stems of Schisandra propinqua var. sinensis, NATURAL PRODUCTS AND BIOPROSPECTING, 2013, 第 7 作者
（40） Phenolic constituents from Parakmeria yunnanensis and their anti-HIV-1 activity, ARCHIVES OF PHARMACAL RESEARCH, 2013, 第 4 作者
（41） Ultrasonic Energy Transference Based on an MEMS ZnO Film Array, Ultrasonic Energy Transference Based on an MEMS ZnO Film Array, CHINESE PHYSICS LETTERS, 2012, 第 9 作者
（42） Four new indole alkaloids from Plantago asiatica, NATURAL PRODUCTS AND BIOPROSPECTING, 2012, 第 1 作者
（43） Kadcoccitones A and B, Two New 6/6/5/5-Fused Tetracyclic Triterpenoids from Kadsura coccinea, ORGANIC LETTERS, 2012, 第 5 作者

   

（ 1 ） 光促进的氮杂环卡宾催化偶联及加成反应研究, 负责人, 国家任务, 2018-01--2020-12
（ 2 ） 基于自由基中间体的卡宾催化反应, 参与, 国家任务, 2017-01--2020-12
（ 3 ） 氮杂环卡宾催化远端不对称反应研究, 负责人, 国家任务, 2021-01--2024-12

（1）双功能硫脲-卡宾催化不对称ε-Michael加成反应研究   中国化学会第33届学术年会   韩旭，代磊，徐园园，张钊飞，高中华，叶松   2023-06-17
（2）Visible light mediated oxo-difluoroalkylation of simple alkenes with DMSO as oxidant   中国化学会第二届全国有机自由基化学会议   夏子豪，高中华，代磊，叶松   2020-04-12
（3）N-Heterocyclic Carbene Catalyzed [3+4] Annulation of Enals and Azadienes: Enantioselective Synthesis of Bioactive Benzofuroazepinones   中国化学会第12届全国天然有机化学学术会议   高中华，陈坤泉，张岩，孔令梅，李艳，叶松   2018-07-28
（4）氮杂环卡宾催化β,β-双取代烯醛与不饱和亚胺的[4 + 3]环加成反应   中国化学会第31届学术年会   高中华，陈坤泉，张岩，叶松   2018-05-05