刘思金-中国科学院大学-UCAS

基本信息

刘思金男博导中国科学院生态环境研究中心
电子邮件： datadisussion@163.com
通信地址：北京市海淀区双清路18号
邮政编码： 100085

研究领域

环境医学与环境毒理学,主要内容包括：（1）环境污染物对血细胞损伤的分子机制；（2）环境肿瘤学及肿瘤进展的机理；（3）人工纳米材料的生物安全性。

招生信息

招生专业

083001-环境科学
0703Z1-化学生物学
071009-细胞生物学

招生方向

环境肿瘤学，纳米生物学
化学生物学，环境科学
环境医学与分子毒理学

教育背景

2001-09--2004-07 中科院遗传发育所博士

工作经历

工作简历

2008-02~2009-08,美国塔芙茨大学医学院, 讲师
2007-07~2008-01,美国哈佛大学医学院, 研究助理
2004-08~2007-06,美国麻省理工学院, 博士后

社会兼职

2012-02-27-今,国家环境与健康专家咨询委员会, 委员

教授课程

环境毒理学研究方法
科研实践Ⅱ
科研实践Ⅰ（环境科学进展讲座）
现代生物学技术在环境健康研究中的应用
环境污染与健康危害进展
环境与健康研究系列讲座
环境与健康研究进展

专利与奖励

奖励信息

（1）国家万人计划, 一等奖, 部委级, 2018
（2）国家青年科技领军人才, 一等奖, 部委级, 2017
（3）十四届中国青年科技奖, 国家级, 2016
（4）高登学术会议(Gordon conference)Nature Travel Award, 一等奖, 其他, 2015
（5）高登学术会议(Gordon conference)Nature Travel Award, 一等奖, 其他, 2015
（6）中国科学院青年科学家奖, 一等奖, 院级, 2015
（7）中国科学院青年科学家奖, 一等奖, 院级, 2015
（8）中国科学院青年科学家奖, 一等奖, 院级, 2015
（9） ****终期考评被评选为优秀, 一等奖, 院级, 2014
（10）中科院2013年度杰出科技成就奖, 一等奖, 院级, 2013
（11）第九届PTS青年科学家奖, 一等奖, 国家级, 2012
（12）美国骨与矿物质学会青年研究者奖, 一等奖, 其他, 2009

专利成果

（ 1 ）一种噻唑烷酮类化合物及其在制备治疗铁紊乱相关疾病药物中的应用, 实用新型, 2014, 第 2 作者, 专利号: 201410698860.7

出版信息

发表论文

[1] Qi, Zijuan, Huang, Xiaofeng, Jing, Jiajun, Feng, Wenya, Xu, Ming, Yan, Li, Gao, Ming, Liu, Sijin, Yu, XueFeng. Amino-modified IONPs potentiates ferroptotic cell death due to the release of Fe ion in the lysosome. JOURNAL OF ENVIRONMENTAL SCIENCES[J]. 2025, 第 8 作者150: 1-13, http://dx.doi.org/10.1016/j.jes.2024.01.034.
[2] Liang, Qiuju, Jing, Jiajun, He, Huiming, Huang, Xiaofeng, Liu, Jianing, Wang, Mingjun, Qi, Zijuan, Zhang, Li e, Huang, Ziang, Yan, Yuanliang, Liu, Sijin, Gao, Ming, Zou, Yunfeng. Manganese induces podocyte injury through regulating MTDH/ALKBH5/ NLRP10 axis: Combined analysis at epidemiology and molecular biology levels. ENVIRONMENT INTERNATIONAL[J]. 2024, 第 11 作者187: http://dx.doi.org/10.1016/j.envint.2024.108672.
[3] Yang, Qiuyuan, Wu, Yue, Liu, Wei, Ou, Xiaojuan, Zhang, Wei, Wang, Jianning, Chang, Yanzhong, Wang, Fudi, Gao, Ming, Liu, Sijin. Zonated iron deposition in the periportal zone of the liver is associated with selectively enhanced lipid synthesis. LIVER INTERNATIONAL[J]. 2024, 第 10 作者44(2): 589-602, http://dx.doi.org/10.1111/liv.15807.
[4] Yu Su, Bin Wang, Xin Tong, Shuchuan Peng, Sijin Liu, Baoshan Xing, Rong Ji. Steam disinfection enhances bioaccessibility of metallic nanoparticles in nano-enabled silicone-rubber baby bottle teats, pacifiers, and teethers. JOURNAL OF ENVIRONMENTAL SCIENCES. 2024, 第 5 作者136: 161-171, http://dx.doi.org/10.1016/j.jes.2022.08.001.
[5] Su, Yu, Wang, Bin, Tong, Xin, Peng, Shuchuan, Liu, Sijin, Xing, Baoshan, Ji, Rong. Steam disinfection enhances bioaccessibility of metallic nanoparticles in nano-enabled silicone-rubber baby bottle teats, pacifiers, and teethers. JOURNAL OF ENVIRONMENTAL SCIENCES[J]. 2024, 第 5 作者136(2): 161-171, http://dx.doi.org/10.1016/j.jes.2022.08.001.
[6] Qi, Yu, Liu, Xiaoxue, Chen, Yucai, Wu, Yue, Sun, Yu, Liu, Xiaoyu, Bao, Qingdong, Zhang, Jingjing, Yuan, Gongqiang, Wang, Ting, Sun, Xiaolei, Liu, Sijin, Gao, Hua. Enhanced Intrusion of Exogenous Airborne Fine Particles toward Eyes in Humans and Animals: Where Damaged Blood-Ocular Barrier Plays a Crucial Role. ENVIRONMENTAL SCIENCE & TECHNOLOGY[J]. 2024, 第 12 作者  通讯作者  58(31): 13636-13647, http://dx.doi.org/10.1021/acs.est.4c01791.
[7] Wu Yue, Yang Tingyun, Yan Bo, Ai Youwei, Chen Fang, Ma Juan, Liu Sijin. ZNT1 Involves Cuproptosis through Regulating MTF1-conduced Expression of MT1X under Copper Overload. ASIAN JOURNAL OF ECOTOXICOLOGY[J]. 2024, 第 7 作者19(4): 53-70, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=7792693&detailType=1.
[8] Liu, Wei, Wu, Yue, Wei, Huaiqing, Ma, Juan, Feng, Wenya, Yang, Qiuyuan, Zhang, Shuping, Ganz, Tomas, Liu, Sijin. Lactate administration improves laboratory parameters in murine models of iron overload. BLOOD. 2024, 第 9 作者  通讯作者  143(11): 1045-1049, http://dx.doi.org/10.1182/blood.2023021695.
[9] 马婉琪, 张娜, 刘思金, 张书平. 重金属砷、镉和铅对树突状细胞的差异化功能损伤. 环境化学[J]. 2024, 第 3 作者43(5): 1474-1483, http://lib.cqvip.com/Qikan/Article/Detail?id=7112278635.
[10] Wang, Pingping, Duan, Fangfang, Lv, Yanwei, Man, Siliang, Liu, Sijin, Liu, Yajun. Long- and Intermediate-Term Ambient Particulate Pollution Is Associated with Increased Osteoarthritis Risk: A Population-Based Prospective Analysis. ENVIRONMENTAL SCIENCE & TECHNOLOGY[J]. 2024, 第 5 作者  通讯作者  58(22): 9536-9547, http://dx.doi.org/10.1021/acs.est.3c10893.
[11] Huang, Xiaofeng, Yang, Renjun, Qi, Zijuan, Wang, Xudong, Yin, Nuoya, Faiola, Francesco, Liu, Sijin, Gao, Ming. Downregulation of m 6 A demethylase ALKBH5 promotes AuNP-induced neural stem cell quiescence via regulating ID4 expression. ENVIRONMENTAL SCIENCE-NANO[J]. 2023, 第 7 作者10(3): 843-854, http://dx.doi.org/10.1039/d2en00734g.
[12] Liu, Shuang, Dong, Jingcun, Fang, Xiaolong, Yan, Xueting, Zhang, He, Hu, Yu, Zhu, Qingqing, Li, Ruibin, Liu, Qian, Liu, Sijin, Liao, Chunyang, Jiang, Guibin. Nanoscale Zinc-Based Metal-Organic Frameworks Induce Neurotoxicity by Disturbing the Metabolism of Catecholamine Neurotransmitters. ENVIRONMENTAL SCIENCE & TECHNOLOGY[J]. 2023, 第 10 作者57(3): 5380-5390,
[13] Ren, Quanzhong, Ma, Juan, Li, Xiaobo, Meng, Qingtao, Wu, Shenshen, Xie, Yusa, Qi, Yu, Liu, Sijin, Chen, Rui. Intestinal Toxicity of Metal Nanoparticles: Silver Nanoparticles Disorder the Intestinal Immune Microenvironment. ACS APPLIED MATERIALS & INTERFACES[J]. 2023, 第 8 作者15(23): 27774-27788, http://dx.doi.org/10.1021/acsami.3c05692.
[14] Huang, Xiaofeng, Yang, Renjun, Qi, Zijuan, Wang, Xudong, Yin, Nuoya, Faiola, Francesco, Liu, Sijin, Gao, Ming. Downregulation of m(6)A demethylase ALKBH5 promotes AuNP-induced neural stem cell quiescence via regulating ID4 expression. ENVIRONMENTAL SCIENCE-NANO[J]. 2023, 第 7 作者10(3): 843-854,
[15] Ren, Jiayu, Zhang, Shupin, Liu, Sijin. Significance and implications of nanoparticle-biological corona fingerprints in diagnosis, prognosis, and therapeutics for diverse disorders. NANOSCALE. 2023, 第 3 作者  通讯作者  15(27): 11422-11433, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:001016148200001.
[16] Qi, Yu, Chen, Yucai, Xia, Tian, Lynch, Iseult, Liu, Sijin. Extra-Pulmonary Translocation of Exogenous Ambient Nanoparticles in the Human Body. ACS NANO[J]. 2023, 第 5 作者  通讯作者  17(1): 12-19,
[17] Ren, Jiayu, Bao, Qingdong, Yang, Yang, Tang, Yuanqi, Zhang, Na, Liu, Guoliang, Zhang, Shuping, Gao, Hua, Liu, Sijin. Nano-eco interactions: a crucial principle for nanotoxicity evaluation. ENVIRONMENTAL SCIENCE-NANO. 2023, 第 9 作者10(12): 3253-3270, http://dx.doi.org/10.1039/d3en00617d.
[18] Yang, Qiuyuan, Wu, Yue, Liu, Wei, Ou, Xiaojuan, Zhang, Wei, Wang, Jianning, Chang, Yanzhong, Wang, Fudi, Gao, Ming, Liu, Sijin. Zonated iron deposition in the periportal zone of the liver is associated with selectively enhanced lipid synthesis. LIVER INTERNATIONAL[J]. 2023, 第 10 作者null(null):
[19] Xu, Lining, Wang, Xudong, Wang, Ruixia, Liu, Sijin, Xu, Ming. Engineered Macrophages: A Safe-by-Design Approach for the Tumor Targeting Delivery of Sub-5 nm Gold Nanoparticles. SMALL[J]. 2023, 第 4 作者19(1):
[20] Xu, Xiaojie, Goros, Ria A, Dong, Zheng, Meng, Xin, Li, Guangle, Chen, Wei, Liu, Sijin, Ma, Juan, Zuo, Yi Y. Microplastics and Nanoplastics Impair the Biophysical Function of Pulmonary Surfactant by Forming Heteroaggregates at the Alveolar-Capillary Interface. ENVIRONMENTAL SCIENCE & TECHNOLOGY[J]. 2023, 第 7 作者57(50): 21050-21060, http://dx.doi.org/10.1021/acs.est.3c06668.
[21] Xu, Lining, Xu, Ming, Sun, Xing, Feliu, Neus, Feng, Liuxing, Parak, Wolfgang J, Liu, Sijin. Quantitative Comparison of Gold Nanoparticle Delivery via the Enhanced Permeation and Retention (EPR) Effect and Mesenchymal Stem Cell (MSC)-Based Targeting. ACS Nano[J]. 2023, 第 7 作者  通讯作者  17(3): 2039-2052, http://dx.doi.org/10.1021/acsnano.2c07295.
[22] Qiu, Jiahuang, Guo, Yifan, Wang, Shunhao, Ren, Quanzhong, Dong, Zheng, Gao, Ming, Ma, Juan, Chen, Shuguang, Liu, Sijin. Newly identified lncRNA-45 promotes breast cancer metastasis through activating the mTOR signaling pathway. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2023, 第 9 作者640(null): 40-49,
[23] Niu, Panhong, Wu, Yuelan, Zeng, Fanxing, Zhang, Shuping, Liu, Sijin, Gao, Hua. Development of nanodrug-based eye drops with good penetration properties and ROS responsiveness for controllable release to treat fungal keratitis. NPG ASIA MATERIALS[J]. 2023, 第 5 作者15(1): http://dx.doi.org/10.1038/s41427-023-00478-9.
[24] Liu, Shuang, Dong, Jingcun, Fang, Xiaolong, Yan, Xueting, Zhang, He, Hu, Yu, Zhu, Qingqing, Li, Ruibin, Liu, Qian, Liu, Sijin, Liao, Chunyang, Jiang, Guibin. Nanoscale Zinc-Based Metal-Organic Frameworks Induce Neurotoxicity by Disturbing the Metabolism of Catecholamine Neurotransmitters. ENVIRONMENTAL SCIENCE & TECHNOLOGY[J]. 2023, 第 10 作者57(3): 5380-5390, http://dx.doi.org/10.1021/acs.est.2c09740.
[25] Huang, Xiaofeng, Yang, Renjun, Qi, Zijuan, Wang, Xudong, Yin, Nuoya, Faiola, Francesco, Liu, Sijin, Gao, Ming. Downregulation of m(6)A demethylase ALKBH5 promotes AuNP-induced neural stem cell quiescence via regulating ID4 expression. ENVIRONMENTAL SCIENCE-NANO[J]. 2023, 第 7 作者10(3): 843-854, http://dx.doi.org/10.1039/d2en00734g.
[26] Xu, Lining, Xu, Ming, Sun, Xing, Feliu, Neus, Feng, Liuxing, Parak, Wolfgang J, Liu, Sijin. Quantitative Comparison of Gold Nanoparticle Delivery via the Enhanced Permeation and Retention (EPR) Effect and Mesenchymal Stem Cell (MSC)-Based Targeting. ACS Nano[J]. 2023, 第 11 作者17(3): 2039-2052, http://dx.doi.org/10.1021/acsnano.2c07295.
[27] Qi, Yu, Chen, Yucai, Yan, Xu, Liu, Wei, Ma, Li, Liu, Yongchun, Ma, Qingxin, Liu, Sijin. Co-Exposure of Ambient Particulate Matter and Airborne Transmission Pathogens: The Impairment of the Upper Respiratory Systems. ENVIRONMENTAL SCIENCE & TECHNOLOGY[J]. 2022, 第 8 作者56(22): 1-10, http://dx.doi.org/10.1021/acs.est.2c03856.
[28] Zhu, Jianqiang, Fu, Qingfeng, Wang, Shunhao, Ren, Liting, Feng, Wenya, Wei, Shuting, Zhang, Zhihong, Xu, Yong, Ganz, Tomas, Liu, Sijin. Palladium Nanoplate-Based IL-6 Receptor Antagonists Ameliorate Cancer-Related Anemia and Simultaneously Inhibit Cancer Progression. NANO LETTERS[J]. 2022, 第 10 作者  通讯作者  22(2): 751-760, http://dx.doi.org/10.1021/acs.nanolett.1c04260.
[29] Gao, Ming, Qi, Zijuan, Deng, Min, Huang, Hongyang, Xu, Zhijie, Guo, Guijie, Jing, Jiajun, Huang, Xiaofeng, Xu, Ming, Kloeber, Jake A, Liu, Sijin, Huang, Jinzhou, Lou, Zhenkun, Han, Jinxiang. The deubiquitinase USP7 regulates oxidative stress through stabilization of HO-1. ONCOGENE[J]. 2022, 第 11 作者41(33): 4018-4027, http://dx.doi.org/10.1038/s41388-022-02403-w.
[30] Bai, Xuan, Lam, Sin Man, Nie, Pengcheng, Xu, Ming, Liu, Sijin, Shui, Guanghou, Hu, Guoqing. Lipidomic analysis probes lipid coronas on hydrophilic nanoparticles from natural lung surfactant. Environmental Science: Nano[J]. 2022, 第 5 作者9(11): 4150-4161, http://dx.doi.org/10.1039/d2en00653g.
[31] Feng, Wenya, Qi, Zijuan, Dong, Zheng, Liu, Wei, Xu, Ming, Gao, Ming, Liu, Sijin. LncRNA MT1DP promotes cadmium-induced DNA replication stress by inhibiting chromatin recruitment of SMARCAL1. SCIENCE OF THE TOTAL ENVIRONMENT[J]. 2022, 第 7 作者807: http://dx.doi.org/10.1016/j.scitotenv.2021.151078.
[32] Liu, Wei, Wu, Yue, Zhang, Na, Liu, Sijin, Zhou, Li. Disordered Maternal and Fetal Iron Metabolism Occurs in Preterm Births in Human. DISEASE MARKERS[J]. 2022, 第 4 作者2022: http://dx.doi.org/10.1155/2022/1664474.
[33] Li, Yifan, Zhu, Qingqing, Bi, Shihao, Zhou, Qunfang, Liang, Yong, Liu, Sijin, Liao, Chunyang. Associations between concentrations of typical ultraviolet filter benzophenones in indoor dust and human hair from China: A human exposure study. SCIENCE OF THE TOTAL ENVIRONMENT[J]. 2022, 第 6 作者841: http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000822963300003.
[34] Wang, Weichao, Liu, Xian, Zhang, Changwen, Sheng, Fei, Song, Shanjun, Li, Penghui, Dai, Shaoqing, Wang, Bin, Lu, Dawei, Zhang, Luyao, Yang, Xuezhi, Zhang, Zhihong, Liu, Sijin, Zhang, Aiqian, Liu, Qian, Jiang, Guibin. Identification of two-dimensional copper signatures in human blood for bladder cancer with machine learning. CHEMICAL SCIENCE[J]. 2022, 第 13 作者13(6): 1648-1656, http://dx.doi.org/10.1039/d1sc06156a.
[35] Dong, Jingcun, Li, Guoliang, Gao, Jia, Zhang, He, Bi, Shihao, Liu, Sijin, Liao, Chunyang, Jiang, Guibin. Catalytic degradation of brominated flame retardants in the environment: New techniques and research highlights. SCIENCE OF THE TOTAL ENVIRONMENT. 2022, 第 6 作者848: http://dx.doi.org/10.1016/j.scitotenv.2022.157695.
[36] Gao, Ming, Qi, Zijuan, Feng, Wenya, Huang, Hongyang, Xu, Zhijie, Dong, Zheng, Xu, Ming, Han, Jinxiang, Kloeber, Jake A, Huang, Jinzhou, Lou, Zhenkun, Liu, Sijin. m6A demethylation of cytidine deaminase APOBEC3B mRNA orchestrates arsenic-induced mutagenesis. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2022, 第 12 作者  通讯作者  298(2): http://dx.doi.org/10.1016/j.jbc.2022.101563.
[37] Qi, Zijuan, Huang, Xiaofeng, Feng, Wenya, Dong, Zheng, Xu, Ming, Cui, Yazhou, Xia, Tian, Liu, Sijin, Gao, Ming, Han, Jinxiang. Significance of m6A regulation in environmental health and safety (EHS) assessment: MWCNTs induced pulmonary toxicity through m6A modifications of mitophagy-related genes. NANO TODAY[J]. 2022, 第 8 作者46: http://dx.doi.org/10.1016/j.nantod.2022.101624.
[38] Qin, Xinyi, Zhuang, Yuan, Ma, Juan, Liu, Sijin, Shi, Baoyou. Enhanced toxicity effects of iron particles together with PFOA in drinking water. ENVIRONMENTAL POLLUTION[J]. 2022, 第 4 作者311: http://dx.doi.org/10.1016/j.envpol.2022.119919.
[39] Yan, Xu, Qi, Yu, Ren, Liting, Ma, Juan, Xu, Ming, Xia, Tian, Liu, Sijin. Silver nanoclusters show advantages in macrophage tracing in vivo and modulation of anti-tumor immuno-microenvironment. JOURNAL OF CONTROLLED RELEASE[J]. 2022, 第 7 作者  通讯作者  348: 470-482, http://dx.doi.org/10.1016/j.jconrel.2022.06.006.
[40] Su, Yu, Hu, Xi, Tang, Hongjie, Lu, Kun, Li, Huimin, Liu, Sijin, Xing, Baoshan, Ji, Rong. Steam disinfection releases micro(nano)plastics from silicone-rubber baby teats as examined by optical photothermal infrared microspectroscopy (vol 17, pg 76, 2022). NATURE NANOTECHNOLOGY. 2022, 第 6 作者17(6): 672-672, http://dx.doi.org/10.1038/s41565-022-01155-8.
[41] Qi, Yu, Chen, Yucai, Xia, Tian, Lynch, Iseult, Liu, Sijin. Extra-Pulmonary Translocation of Exogenous Ambient Nanoparticles in the Human Body. ACS NANO[J]. 2022, 第 5 作者  通讯作者  17(1): 1-8, http://dx.doi.org/10.1021/acsnano.2c09299.
[42] Qi, Yu, Chen, Yucai, Yan, Xu, Liu, Wei, Ma, Li, Liu, Yongchun, Ma, Qingxin, Liu, Sijin. Co-Exposure of Ambient Particulate Matter and Airborne Transmission Pathogens: The Impairment of the Upper Respiratory Systems. ENVIRONMENTAL SCIENCE & TECHNOLOGY[J]. 2022, 第 8 作者56(22): 1-10, http://dx.doi.org/10.1021/acs.est.2c03856.
[43] Zhu, Jianqiang, Fu, Qingfeng, Wang, Shunhao, Ren, Liting, Feng, Wenya, Wei, Shuting, Zhang, Zhihong, Xu, Yong, Ganz, Tomas, Liu, Sijin. Palladium Nanoplate-Based IL-6 Receptor Antagonists Ameliorate Cancer-Related Anemia and Simultaneously Inhibit Cancer Progression. NANO LETTERS[J]. 2022, 第 11 作者22(2): 751-760, http://dx.doi.org/10.1021/acs.nanolett.1c04260.
[44] Gao, Ming, Qi, Zijuan, Deng, Min, Huang, Hongyang, Xu, Zhijie, Guo, Guijie, Jing, Jiajun, Huang, Xiaofeng, Xu, Ming, Kloeber, Jake A, Liu, Sijin, Huang, Jinzhou, Lou, Zhenkun, Han, Jinxiang. The deubiquitinase USP7 regulates oxidative stress through stabilization of HO-1. ONCOGENE[J]. 2022, 第 0 作者41(33): 4018-4027, http://dx.doi.org/10.1038/s41388-022-02403-w.
[45] Bai, Xuan, Lam, Sin Man, Nie, Pengcheng, Xu, Ming, Liu, Sijin, Shui, Guanghou, Hu, Guoqing. Lipidomic analysis probes lipid coronas on hydrophilic nanoparticles from natural lung surfactant. ENVIRONMENTAL SCIENCE-NANO[J]. 2022, 第 5 作者9(11): 4150-4161, http://dx.doi.org/10.1039/d2en00653g.
[46] Feng, Wenya, Qi, Zijuan, Dong, Zheng, Liu, Wei, Xu, Ming, Gao, Ming, Liu, Sijin. LncRNA MT1DP promotes cadmium-induced DNA replication stress by inhibiting chromatin recruitment of SMARCAL1. SCIENCE OF THE TOTAL ENVIRONMENT[J]. 2022, 第 7 作者807: http://dx.doi.org/10.1016/j.scitotenv.2021.151078.
[47] Liu, Wei, Wu, Yue, Zhang, Na, Liu, Sijin, Zhou, Li. Disordered Maternal and Fetal Iron Metabolism Occurs in Preterm Births in Human. DISEASE MARKERS[J]. 2022, 第 4 作者2022: http://dx.doi.org/10.1155/2022/1664474.
[48] Li, Yifan, Zhu, Qingqing, Bi, Shihao, Zhou, Qunfang, Liang, Yong, Liu, Sijin, Liao, Chunyang. Associations between concentrations of typical ultraviolet filter benzophenones in indoor dust and human hair from China: A human exposure study. SCIENCE OF THE TOTAL ENVIRONMENT[J]. 2022, 第 6 作者841:
[49] Wang, Weichao, Liu, Xian, Zhang, Changwen, Sheng, Fei, Song, Shanjun, Li, Penghui, Dai, Shaoqing, Wang, Bin, Lu, Dawei, Zhang, Luyao, Yang, Xuezhi, Zhang, Zhihong, Liu, Sijin, Zhang, Aiqian, Liu, Qian, Jiang, Guibin. Identification of two-dimensional copper signatures in human blood for bladder cancer with machine learning. CHEMICAL SCIENCE[J]. 2022, 第 13 作者13(6): 1648-1656, http://dx.doi.org/10.1039/d1sc06156a.
[50] Gao, Ming, Qi, Zijuan, Feng, Wenya, Huang, Hongyang, Xu, Zhijie, Dong, Zheng, Xu, Ming, Han, Jinxiang, Kloeber, Jake A, Huang, Jinzhou, Lou, Zhenkun, Liu, Sijin. m6A demethylation of cytidine deaminase APOBEC3B mRNA orchestrates arsenic-induced mutagenesis. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2022, 第 11 作者298(2): http://dx.doi.org/10.1016/j.jbc.2022.101563.
[51] Qi, Zijuan, Huang, Xiaofeng, Feng, Wenya, Dong, Zheng, Xu, Ming, Cui, Yazhou, Xia, Tian, Liu, Sijin, Gao, Ming, Han, Jinxiang. Significance of m6A regulation in environmental health and safety (EHS) assessment: MWCNTs induced pulmonary toxicity through m6A modifications of mitophagy-related genes. NANO TODAY[J]. 2022, 第 8 作者46: http://dx.doi.org/10.1016/j.nantod.2022.101624.
[52] Qin, Xinyi, Zhuang, Yuan, Ma, Juan, Liu, Sijin, Shi, Baoyou. Enhanced toxicity effects of iron particles together with PFOA in drinking water. ENVIRONMENTAL POLLUTION[J]. 2022, 第 4 作者311: http://dx.doi.org/10.1016/j.envpol.2022.119919.
[53] Yan, Xu, Qi, Yu, Ren, Liting, Ma, Juan, Xu, Ming, Xia, Tian, Liu, Sijin. Silver nanoclusters show advantages in macrophage tracing in vivo and modulation of anti-tumor immuno-microenvironment. JOURNAL OF CONTROLLED RELEASE[J]. 2022, 第 11 作者348: 470-482, http://dx.doi.org/10.1016/j.jconrel.2022.06.006.
[54] Su, Yu, Hu, Xi, Tang, Hongjie, Lu, Kun, Li, Huimin, Liu, Sijin, Xing, Baoshan, Ji, Rong. Steam disinfection releases micro(nano)plastics from silicone-rubber baby teats as examined by optical photothermal infrared microspectroscopy (vol 17, pg 76, 2022). NATURE NANOTECHNOLOGY. 2022, 第 6 作者17(6): 672-672, http://dx.doi.org/10.1038/s41565-022-01155-8.
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[509] Liu, SiJin, Cai, ZiWei, Liu, YaJun, Dong, MeiYu, Sun, LiQiu, Hu, GuoFa, Wei, YingYun, Lao, WeiDe. Role of nucleostemin in growth regulation of gastric cancer, liver cancer and other malignancies. WORLD JOURNAL OF GASTROENTEROLOGY[J]. 2004, 第 1 作者10(9): 1246-1249, http://lib.cqvip.com/Qikan/Article/Detail?id=9792591.
[510] 刘思国, 魏影允, 胡国法, 高虹, 刘思金, 劳为德. 人α-乳白蛋白在转基因小鼠乳汁中的动态表达图貌. 中国科学：C辑[J]. 2003, 第 5 作者33(4): 317-322, http://lib.cqvip.com/Qikan/Article/Detail?id=8191596.
[511] 刘思国, 魏影允, 胡国法, 高虹, 刘思金, 劳为德. 人α-乳白蛋白在转基因小鼠乳汁中的动态表达图貌. 中国科学：C辑[J]. 2003, 第 5 作者33(4): 317-322, http://lib.cqvip.com/Qikan/Article/Detail?id=8191596.
[512] 刘思金, 胡国法, 刘思国, 魏影允, 薛延, 劳为德. 人类骨桥蛋白（hOPN）在细胞增殖中的功能研究. 高技术通讯[J]. 2003, 第 1 作者13(2): 25-28,40, http://lib.cqvip.com/Qikan/Article/Detail?id=7464357.
[513] 刘思金, 劳为德. 骨桥蛋白的研究进展. 国外医学：老年医学分册[J]. 2003, 第 1 作者24(5): 232-236, http://lib.cqvip.com/Qikan/Article/Detail?id=8445507.
[514] 贾桂英, 刘思金, 刘亚军. 雌激素缺乏致细胞因子水平变化对骨代谢的影响. 中国临床康复[J]. 2003, 第 2 作者7(24): 3362-3363, http://lib.cqvip.com/Qikan/Article/Detail?id=8447837.
[515] 刘思金, 贾桂英, 薛延, 王芊, 刘亚军, 劳为德. 淫羊藿总黄酮对体外培养的人成骨样细胞增殖和骨形成功能的影响. 中国新药杂志[J]. 2003, 第 1 作者12(6): 432-435, http://lib.cqvip.com/Qikan/Article/Detail?id=8093193.
[516] 高虹, 刘思国, 刘思金, 魏影允, 胡国法, 张传生, 劳为德. 嵌合分子VEGF^＋的构建、表达及其抗血管生成和抗肿瘤活性. 中国生物工程杂志[J]. 2003, 第 3 作者23(3): 62-66, http://lib.cqvip.com/Qikan/Article/Detail?id=7587543.
[517] 刘思国, 魏影允, 胡国法, 高虹, 刘思金, 劳为德. ��-��. 中国科学：C辑[J]. 2003, 第 5 作者33(4): 317-322, http://lib.cqvip.com/Qikan/Article/Detail?id=8191596.
[518] 刘思国, 魏影允, 胡国法, 高虹, 刘思金, 劳为德. ��-��. 中国科学：C辑[J]. 2003, 第 5 作者33(4): 317-322, http://lib.cqvip.com/Qikan/Article/Detail?id=8191596.
[519] 刘思金, 胡国法, 刘思国, 魏影允, 薛延, 劳为德. ��hOPN��. 高技术通讯[J]. 2003, 第 1 作者13(2): 25-28,40, http://lib.cqvip.com/Qikan/Article/Detail?id=7464357.
[520] 贾桂英, 刘思金, 刘亚军. ��. 中国临床康复[J]. 2003, 第 2 作者7(24): 3362-3363, http://lib.cqvip.com/Qikan/Article/Detail?id=8447837.
[521] 刘思金, 劳为德. ��. 国外医学：老年医学分册[J]. 2003, 第 1 作者24(5): 232-236, http://lib.cqvip.com/Qikan/Article/Detail?id=8445507.
[522] 刘思金, 贾桂英, 薛延, 王芊, 刘亚军, 劳为德. ��. 中国新药杂志[J]. 2003, 第 1 作者12(6): 432-435, http://lib.cqvip.com/Qikan/Article/Detail?id=8093193.
[523] 高虹, 刘思国, 刘思金, 魏影允, 胡国法, 张传生, 劳为德. ��VEGF^��. 中国生物工程杂志[J]. 2003, 第 3 作者23(3): 62-66, http://lib.cqvip.com/Qikan/Article/Detail?id=7587543.
[524] 刘思金, 韦庆申, 陈星飚, 刘亚军, 王红霞, 王芊, 薛延. 阿化磷酸钠对人成骨样细胞增殖和分化的影响. 中国新药杂志[J]. 2002, 第 1 作者11(7): 543-546, http://lib.cqvip.com/Qikan/Article/Detail?id=6554619.
[525] 陈星飚, 刘思金, 薛延. 月经初潮早晚对女大学生骨骼生长发育与骨量的影响. 中国运动医学杂志[J]. 2002, 第 2 作者21(1): 54-56, http://lib.cqvip.com/Qikan/Article/Detail?id=5860729.
[526] 刘思金, 韦庆申, 陈星飚, 刘亚军, 王红霞, 王芊, 薛延. ��. 中国新药杂志[J]. 2002, 第 1 作者11(7): 543-546, http://lib.cqvip.com/Qikan/Article/Detail?id=6554619.
[527] 陈星飚, 刘思金, 薛延. ��. 中国运动医学杂志[J]. 2002, 第 2 作者21(1): 54-56, http://lib.cqvip.com/Qikan/Article/Detail?id=5860729.
[528] Xinyi Qin, Yuan Zhuang, Juan Ma, Sijin Liu, Baoyou Shi. Enhanced toxicity effects of iron particles together with PFOA in drinking water. ENVIRONMENTAL POLLUTION. 第 4 作者http://dx.doi.org/10.1016/j.envpol.2022.119919.
[529] Zijuan Qi, Xiaofeng Huang, Wenya Feng, Zheng Dong, Ming Xu, Yazhou Cui, Tian Xia, Sijin Liu, Ming Gao, Jinxiang Han. Significance of m6A Regulation in Environmental Health and Safety (EHS) Assessment: MWCNTs Induced Pulmonary Toxicity through m6A Modifications of Mitophagy-Related Genes. NANO TODAY. 第 8 作者http://dx.doi.org/10.1016/j.nantod.2022.101624.
[530] Jie Zhang, Sijin Liu, Jinxiang Han, Zhe Wang, Shuping Zhang. Developmental toxicity of silver nanoparticles: Calls for more attention and research efforts. MATERIALS & DESIGN. 第 2 作者http://dx.doi.org/10.1016/j.matdes.2021.109611.
[531] Xinyi Qin, Yuan Zhuang, Juan Ma, Sijin Liu, Baoyou Shi. Enhanced toxicity effects of iron particles together with PFOA in drinking water. ENVIRONMENTAL POLLUTION. 第 4 作者http://dx.doi.org/10.1016/j.envpol.2022.119919.
[532] Zijuan Qi, Xiaofeng Huang, Wenya Feng, Zheng Dong, Ming Xu, Yazhou Cui, Tian Xia, Sijin Liu, Ming Gao, Jinxiang Han. Significance of m6A Regulation in Environmental Health and Safety (EHS) Assessment: MWCNTs Induced Pulmonary Toxicity through m6A Modifications of Mitophagy-Related Genes. NANO TODAY. 第 8 作者http://dx.doi.org/10.1016/j.nantod.2022.101624.
[533] Jie Zhang, Sijin Liu, Jinxiang Han, Zhe Wang, Shuping Zhang. Developmental toxicity of silver nanoparticles: Calls for more attention and research efforts. MATERIALS & DESIGN. 第 2 作者http://dx.doi.org/10.1016/j.matdes.2021.109611.

科研活动

科研项目

（ 1 ）典型有机磷农药和重金属的联合毒性效应与作用机理, 负责人, 国家任务, 2011-01--2013-12
（ 2 ）持久性有机污染物的分子毒理学研究, 负责人, 中国科学院计划, 2009-09--2013-12
（ 3 ）多氯联苯(PCBs)暴露对乳腺癌肿瘤转移的影响及相关分子机制的研究, 负责人, 国家任务, 2011-01--2013-12
（ 4 ）纳米银的胚胎发育毒性机理研究, 负责人, 国家任务, 2012-01--2015-12
（ 5 ）人工纳米材料环境效应的分子作用机制研究, 负责人, 国家任务, 2014-01--2018-12
（ 6 ）典型污染物对肿瘤细胞增殖与转移的影响机制, 负责人, 中国科学院计划, 2014-07--2019-06
（ 7 ）环境污染物的毒理与健康效应, 负责人, 国家任务, 2015-01--2018-12
（ 8 ）高环境暴露风险金属纳米材料的胚胎发育毒性, 负责人, 国家任务, 2017-01--2021-12
（ 9 ）大气细颗粒物肺内转化对其毒性的影响机制, 负责人, 国家任务, 2020-01--2024-12
（ 10 ）大气细颗粒物与肺内生物分子的相互作用及损伤机制, 负责人, 中国科学院计划, 2020-01--2022-12
（ 11 ）大气细颗粒物重塑肺内免疫微环境并改变机体对病毒感染敏感性的作用机制, 负责人, 国家任务, 2022-01--2024-12

参与会议

（1）Biotransformation of graphene oxide in lung fluids significantly alters its inherent properties and in vitro and in vivo bio-interactions    第255届美国化学会年会   2018-08-23
（2）Molybdenum disulfide (MoS2)/graphene oxide (GO) nanocomposites show favorable lung targeting and enhanced drug loading/tumor-killing efficacy with desirable biocompatibility    第255届美国化学会年会   2018-08-22
（3）重金属等污染物的毒性靶点识别与毒性通路    2018环境与健康学术会议   2018-08-14
（4）重金属等污染物的毒性靶点识别与毒性通路    2018环境与健康学术会议   2018-08-14
（5）石墨烯的毒性机制与转化毒理研究    第二届全国环境纳米技术及生物效应学术研讨会（2018）   2018-06-18
（6）石墨烯的毒性机制与转化毒理研究    第二届全国环境纳米技术及生物效应学术研讨会（2018）   2018-06-18
（7）Silver nanoparticles repress hemoglobin transcription through an epigenetic mechanism: altering the methylation status of histone 3   2015-12-15
（8）Environmental pollutants, iron metabolism, and cancer risk   2015-11-15
（9）Silver Nanoparticles Induced RNA Polymerase-Silver Binding and RNA Transcription Inhibition in Erythroid Progenitor Cells   2013-08-12

指导学生

已指导学生

张书平博士研究生 083001-环境科学

王立新博士研究生 083001-环境科学

王哲博士研究生 083001-环境科学

王雷硕士研究生 430130-环境工程

王小岩博士研究生 083001-环境科学

郭文丽博士研究生 083001-环境科学

刘静博士研究生 083001-环境科学

张洁博士研究生 083001-环境科学

高婕硕士研究生 083001-环境科学

马娟博士研究生 083001-环境科学

吴亚坤博士研究生 083001-环境科学

陈禹男硕士研究生 077601-环境科学

尹春阳博士研究生 070303-有机化学

陈永久博士研究生 083001-环境科学

汪顺浩博士研究生 070303-有机化学

申心铭硕士研究生 085238-生物工程

任泉仲硕士研究生 077601-环境科学

现指导学生

杨秋源博士研究生 083001-环境科学

刘伟博士研究生 083001-环境科学

闫旭博士研究生 083001-环境科学

冯文雅博士研究生 070303-有机化学

王瑞霞博士研究生 083001-环境科学

丘嘉煌博士研究生 083001-环境科学

徐立宁博士研究生 083001-环境科学

陈誉才硕士研究生 086000-生物与医药

董政博士研究生 083001-环境科学