基本信息
陈懿  女  博导  中国科学院理化技术研究所
email: yichen@mail.ipc.ac.cn
address: 中国科学院理化技术研究所
postalCode: 100190

招生信息

   
招生专业
070303-有机化学
招生方向
有机化学

教育背景

1993-09--中国科学院感光化学研究所   博士
1988-09--江西师范大学化学系   硕士
1982-09--江西师范大学化学系   学士

工作经历

   
工作简历
2004-01~现在, 中国科学院理化技术研究所, 研究员
2001-07~现在, 中国科学院理化技术研究所, 副研
2000-01~现在, 英国Oxford大学分子科学中心, 研究助理
1997-01~现在, 英国Sunderland大学化学系, 博士后
1993-09~现在, 中国科学院感光化学研究所, 博士
1988-09~现在, 江西师范大学化学系, 硕士
1982-09~现在, 江西师范大学化学系, 学士

教授课程

有机光化学
光化学绿色合成与催化
有机光化学(二)
有机光化学(一)
有机光化学(一)

专利与奖励

   
专利成果
( 1 ) 一种抗绿脓杆菌的药物组合物及其制备方法和用途, 2021, 第 1 作者, 专利号: CN112294807A

( 2 ) 一种提高天然产物抗菌活性的联合体系及其应用, 2019, 第 1 作者, 专利号: CN109700803A

( 3 ) 一种氟原子取代的氰基异佛尔酮苯乙烯化合物、晶体化合物及制备方法, 2017, 第 1 作者, 专利号: CN106946739A

( 4 ) 提高脱水穿心莲内酯水溶性、酯-水分配系数的方法及新型脱水穿心莲内酯、制备、应用, 2017, 第 1 作者, 专利号: CN106467508A

( 5 ) 1,3,5-三(4-N,N’-二烷基苯胺)苯类有机化合物及其合成方法, 2014, 第 1 作者, 专利号: CN103524355A

( 6 ) 由3,4-二芳基-2,5-二氢噻吩合成3,4-二芳基噻吩的方法, 2012, 第 1 作者, 专利号: CN101318951B

( 7 ) 杂环取代的2,5-二氢吡咯类光致变色化合物及其合成方法和用途, 2006, 第 5 作者, 专利号: CN1250543C

( 8 ) 噁唑取代俘精酰亚胺类光致变色化合物及其合成方法和用途, 2006, 第 4 作者, 专利号: CN1239500C

( 9 ) 双杂环取代的俘精酸酐类光致变色化合物及其合成方法和用途, 2003, 第 3 作者, 专利号: CN1446878A

出版信息

   
发表论文
(1) Two-Photon Fluorescent Probes for Amyloid-�� Plaques Imaging In Vivo, MOLECULES, 2023, 第 1 作者
(2) Two-photon AIEgen based on dicyanoisophorone derivative: Synthesis, characterization and cells imaging, JOURNAL OF MOLECULAR STRUCTURE, 2022, 第 3 作者  通讯作者
(3) Recent advances in AIEgens for three-photon fluorescence bioimaging, MATERIALS TODAY CHEMISTRY, 2022, 
(4) Circularly polarized luminescence based on small organic fluorophores, MATERIALS TODAY CHEMISTRY, 2022, 
(5) Recent Advances in Excimer-Based Fluorescence Probes for Biological Applications, MOLECULES, 2022, 第 1 作者  通讯作者
(6) Recent progress in fluorescent aptasensors for the detection of aflatoxin B1 in food, ANALYTICAL METHODS, 2022, 第 1 作者  通讯作者
(7) Evaluation of Apigenin Inhibiting Lactate Dehydrogenase Activity Based on CdTe Quantum Dots Fluorescence, JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 2021, 第 8 作者  通讯作者
(8) Nanoscale metal organic frameworks inhibition of pyruvate kinase of M2, Chinese Chemical Letters, 2021, 第 6 作者
(9) Recent progress in natural product-based inhibitor screening with enzymatic fluorescent probes, ANALYTICAL METHODS, 2021, 第 1 作者  通讯作者
(10) Recent advances in fluorescent probes for extracellular pH detection and imaging, ANALYTICAL BIOCHEMISTRY, 2021, 第 1 作者  通讯作者
(11) Advances in fluorescent probes for detection and imaging of endogenous tyrosinase activity, ANALYTICAL BIOCHEMISTRY, 2020, 第 1 作者  通讯作者
(12) Fluorescent probes for detection and bioimaging of leucine aminopeptidase, MATERIALS TODAY CHEMISTRY, 2020, 
(13) Recent developments of fluorescent probes for detection and bioimaging of nitric oxide, NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2020, 第 1 作者  通讯作者
(14) Design and construction of COX-2 specific fluorescent probes, MOLECULAR AND CELLULAR PROBES, 2019, 第 1 作者  通讯作者
(15) Two/multi-photon induced up-conversion emission of dicyanoisophorone derivative, JOURNAL OF PHOTOCHEMISTRY & PHOTOBIOLOGY, A: CHEMISTRY, 2018, 第 3 作者
(16) Two-photon induced excimer emission of dicyanoisophorone derivative in crystal state, JOURNAL OF LUMINESCENCE, 2018, 第 3 作者  通讯作者
(17) Synthesis of 9,10-distyrylanthracene derivative and its one- and two-photon induced emission in solid state, JOURNAL OF PHOTOCHEMISTRY & PHOTOBIOLOGY, A: CHEMISTRY, 2018, 第 3 作者
(18) Two/multi-photon induced up-conversion emission of dicyanoisophorone derivative, JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2018, 第 3 作者  通讯作者
(19) Synthesis of 9,10-distyrylanthracene derivative and its one- and two-photon induced emission in solid state, JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2018, 第 3 作者  通讯作者
(20) An efficient photorelease of Zn2+ with turn-on fluorescence monitoring, JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2017, 第 2 作者  通讯作者
(21) A fluorescent dye with large Stokes shift and high stability: synthesis and application to live cell imaging, RSC ADVANCES, 2017, 第 4 作者  通讯作者
(22) One-pot synthesis of a near-infrared fluorophore for living cells imaging, DYES AND PIGMENTS, 2017, 第 3 作者  通讯作者
(23) A fluorescent dye with large Stokes shift and high stability: synthesis and application to living cells imaging, RSC Adv, 2017, 第 1 作者  通讯作者
(24) Oligo-polyethene glycol (PEG)-modified 14-deoxy-11,12-didehydroandrographolide derivatives: synthesis, solubility and anti-bacterial activity, TETRAHEDRON, 2016, 第 2 作者  通讯作者
(25) Regio-selective pegylation of 14-deoxy-11,12-didehydroandrographolide and their biological evaluation, TETRAHEDRON, 2016, 第 3 作者  通讯作者
(26) Excited-state intramolecular single and double proton transfer emission of 2,5-bis(benzoxazol-2-yl)thiophene-3,4-diol, DYES AND PIGMENTS, 2016, 第 2 作者  通讯作者
(27) Two-photon pumped emission of polymeric thin film doped with dicyanopyranone derivative, RSC ADVANCES, 2015, 第 2 作者  通讯作者
(28) Red fluorescence thin film based on a strong pushepull dicyanoisophorone system, Dyes and Pigments, 2015, 第 1 作者  通讯作者
(29) Red fluorescence thin film based on a strong push���pull dicyanoisophorone system, DYES AND PIGMENTS, 2015, 第 3 作者  通讯作者
(30) 2,5-双(对二甲氨基苯乙烯基)吡嗪的双光子诱导荧光性质, Two-photon-induced Fluorescence of 2,5-Bis (4-dimethylaminostyryl) pyrazine, 影像科学与光化学, 2015, 第 2 作者
(31) Synthesis of a water soluble red fluorescent dye and its application toliving cells imaging, DYES AND PIGMENTS, 2015, 第 4 作者  通讯作者
(32) Photorelease of La3+ with turn-on fluorescent detection, JOURNAL OF PHOTOCHEMISTRY & PHOTOBIOLOGY, A: CHEMISTRY, 2014, 第 3 作者
(33) Photorelease of La3+ with turn-on fluorescent detection, JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2014, 第 3 作者  通讯作者
(34) A highly stable and water-soluble fluorescent dye for fluorescence imaging of living cells, JOURNAL OF MATERIALS CHEMISTRY B, 2014, 第 3 作者  通讯作者
(35) Photoactivatable turn-on fluorescence based on the photo-cleavage of the C-Br bond in 1,2-bis(5-(bromoethyl)benzoxazol-2-yl)ethane, NEW JOURNAL OF CHEMISTRY, 2014, 第 3 作者  通讯作者
(36) Synthesis and fluorescence of dicyanoisophorone derivatives, DYES AND PIGMENTS, 2013, 第 2 作者  通讯作者
(37) Synthesis and photophysical properties of thiolactone derivatives, TETRAHEDRON, 2013, 第 2 作者  通讯作者
(38) Synthesis and fluorescence of dicyanoisophorone derivatives, DYES AND PIGMENTS, 2013, 第 2 作者  通讯作者
(39) Force-induced cleavage of C���O bond in photochromic naphthopyrans, MATERIALS CHEMISTRY AND PHYSICS, 2013, 第 2 作者  通讯作者
(40) Synthesis and photophysical properties of thiolactone derivatives, TETRAHEDRON, 2013, 第 2 作者  通讯作者
(41) One-pot synthesis of N, N, N, N-tetraethyl-9H-xanthene-3,6-diamine and its conversion to pyronine B, DYES AND PIGMENTS, 2013, 第 2 作者  通讯作者
(42) Selective photoconversion of photochromic diarylethenes and their properties, NEW JOURNAL OF CHEMISTRY, 2012, 第 2 作者  通讯作者
(43) Photoconversion of a Protonated Diarylethene Derivative, JOURNAL OF PHYSICAL CHEMISTRY A, 2012, 第 4 作者  通讯作者
(44) Modulation of absorption and fluorescence of photochromic diarylethene by intramolecular hydrogen bond, JOURNAL OF PHYSICAL ORGANIC CHEMISTRY, 2012, 第 2 作者  通讯作者
(45) Photo-controlled metal-ion (Zn2+ and Cd2+) release in aqueous Tween-20 micelle solution, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2012, 第 2 作者  通讯作者
(46) Mercury ion induced activation of the CeO bond in a photo-responsive spiropyran, Dyes and Pigments, 2011, 第 1 作者  通讯作者
(47) Construction and Properties of a Phototriggered Cd2+ Release System, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2011, 第 2 作者  通讯作者
(48) Colorimetric probing of Hg2+ in both solution and thin film, ANALYTICAL METHODS, 2011, 第 2 作者  通讯作者
(49) Modification of a photochromic 3-aryl-3-(a-naphthalene)-3H-naphtho[2,1-b] pyran system with a fast fading speed in solution and in a rigid polymer matrix, Journal of Materials Chemistry, 2011, 第 1 作者  通讯作者
(50) 新型二芳基乙烯光致变色化合物的制备及其应用基础研究, 影像科学与光化学, 2011, 第 2 作者
(51) Modulation of color change and photocyclization of diarylethene with metal complex, JOURNAL OF PHYSICAL ORGANIC CHEMISTRY, 2011, 第 2 作者  通讯作者
(52) Mercury ion induced activation of the C-O bond in a photo-responsive spiropyran, DYES AND PIGMENTS, 2011, 第 2 作者  通讯作者
(53) Construction of multi-level fluorescent switch using photochromic diarylethene and fluorescent dye, DYES AND PIGMENTS, 2011, 第 2 作者  通讯作者
(54) Modification of a photochromic 3-aryl-3-(alpha-naphthalene)-3H-naphtho2,1-bpyran system with a fast fading speed in solution and in a rigid polymer matrix, JOURNAL OF MATERIALS CHEMISTRY, 2011, 第 2 作者  通讯作者
(55) Selective photochromism and solvatochromism of a diarylethene with different bridge units, JOURNAL OF MATERIALS CHEMISTRY, 2011, 第 2 作者  通讯作者
(56) Rapid fading of 3H-naphtho2,1-bpyrans with protonation of N,N-disubstituted group, JOURNAL OF MATERIALS CHEMISTRY, 2011, 第 2 作者  通讯作者
(57) Carbon dioxide and water as a key for unlocking photochromism of diarylethene derivative, JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2010, 第 2 作者  通讯作者
(58) A strategy for the design of photochromic naphthopyrans with large optical density at photosteady state and fast fading speed at ambient temperature in the dark, JOURNAL OF MATERIALS CHEMISTRY, 2010, 第 2 作者  通讯作者
(59) Simple and rapid detection of aromatic amines using a thin layer chromatography plate, ANALYTICAL METHODS, 2010, 第 2 作者  通讯作者
(60) 'locking and unlocking control' of photochromism of naphthopyran derivative, JOURNAL OF PHYSICAL ORGANIC CHEMISTRY, 2010, 第 2 作者  通讯作者
(61) Photo-controlled zn2+ release system with dual binding-sites and turn-on fluorescence, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2010, 第 2 作者  通讯作者
(62) Construction and properties of multi-addressable switching system based on a photochromic diarylethene, JOURNAL OF MATERIALS CHEMISTRY, 2009, 第 2 作者  通讯作者
(63) Lewis acid and base triggered molecular switch, JOURNAL OF MATERIALS CHEMISTRY, 2009, 第 2 作者  通讯作者
(64) A bifunctional metal probe with independent signal outputs and regulable detection limits, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2009, 第 2 作者  通讯作者
(65) 光致变色二芳基乙烯抗疲劳特性实验研究, Experimental Measurement of Fatigue Resistance of a Photochromic Diarylethene, 光子学报, 2009, 第 5 作者
(66) The Photochromism and Fluorescence of Diarylethenes with a Imidazole Bridge Unit: A Strategy for the Design of Turn-on Fluorescent Diarylethene System, JOURNAL OF PHYSICAL CHEMISTRY A, 2009, 第 2 作者  通讯作者
(67) Phototriggered metal-ion release from phenolic schiff bases: a system for metal-ion photodelivery, CHEMPHYSCHEM, 2009, 第 2 作者  通讯作者
(68) Kinetic characterization of photoinduced anisotropy in diarylethene film, OPTICS COMMUNICATIONS, 2009, 第 5 作者
(69) Photochromic Properties of Naphthopyrans - PMMA Thin Film, MOLECULAR CRYSTALS AND LIQUID CRYSTALS, 2009, 第 2 作者  通讯作者
(70) A light-modulated chemosensor for methanol with ratiometry and colorimetry, ANALYTICA CHIMICA ACTA, 2009, 第 2 作者  通讯作者
(71) 二芳基乙烯光致各向异性动态特性研究, Dynamic properties of photoinduced anisotropy of diarylethene, 物理学报, 2008, 第 5 作者
(72) Dynamic properties of photoinduced anisotropy of diarylethene, ACTA PHYSICA SINICA, 2008, 第 5 作者
(73) Construction and photoswitching properties of fluorescent diarylethenes, JOURNAL OF MATERIALS CHEMISTRY, 2007, 第 2 作者  通讯作者
(74) Oxidation of 3,4-diaryl-2,5-dihydrothiophenes to 3,4-diarylthiophenes using CuBr2: Simple and efficient preparation of 3,4-diarylthiophenes, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2007, 第 2 作者
(75) Synthesis and photophysical properties of 1,4-bis(4,5-diarylimidazol) benzene dyes, JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2007, 第 2 作者  通讯作者
(76) Electrochemical switch based on the photoisomerization of a diarylethene derivative, JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 2007, 第 3 作者  通讯作者
(77) One-pot oxidation and bromination of 3,4-diaryl-2,5-dihydrothiophenes using Br-2: Synthesis and application of 3,4-diaryl-2,5-dibromothiophenes, JOURNAL OF ORGANIC CHEMISTRY, 2007, 第 2 作者  通讯作者
(78) A selective, fluorescent probe for Hg2+ detection in aqueous solution, JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2007, 第 2 作者  通讯作者
(79) Combination of fluorescent switch and electrochemical switch based on a photochromic diarylethene, NEW JOURNAL OF CHEMISTRY, 2006, 第 2 作者  通讯作者
(80) 双色俘精酸酐薄膜的双波长图像光存储, 光学学报, 2005, 第 3 作者
(81) 含S,N杂环戊烯桥头的二芳烯光致变色化合物的合成及性质研究, Synthesis and Properties of Diarylethenes with S, N-Hetercyclopentene Bridging Units, 感光科学与光化学, 2005, 第 2 作者
(82) 吡咯俘精酸酐的光致各向异性研究, Photoinduced Anisotropy in Pyrrylfulgide/PMMA Film, 光子学报, 2004, 第 8 作者
(83) 吲哚俘精酰胺的偏振全息图像光存储实验研究, Polarization holographic image storage with indolylfulgimide, 物理学报, 2004, 第 3 作者
(84) 有机光致变色材料——吡咯俘精酸酐的并行光存储实验, 科学通报, 2003, 第 3 作者
(85) 共轭读出法消除光致变色材料全息记录中的相位畸变, Phase Aberration Correction Using Conjugated Wave Reconstruction in Holography of Photochromic Material, 光子学报, 2003, 第 3 作者
(86) 光敏变色双呋喃俘精酸酐的合成及其在平行图象存储中的应用, 中国科学:B辑, 2003, 第 2 作者
(87) 光致变色双呋喃俘精酸酐的合成及其在平行图像存储中的应用, 中国科学. B辑, 化学, 2003, 第 2 作者
(88) 可擦写俘精酸酐/PMMA薄膜的全息记录特性研究, 光子学报, 2003, 第 7 作者
(89) 吡咯俘精酸酐的图像光存储特性, Optical Image Storage Using Pyrryl Fulgide, 光学学报, 2003, 第 8 作者
(90) 双光子光化学, Development of Twophoton-photochemistry Development, 山西大学学报:自然科学版, 2002, 第 4 作者
(91) 氧Weng盐分子在受限制体系中的电荷转移和发光行为, 感光科学与光化学, 1997, 第 1 作者
(92) 室温下氧Wong盐非极性溶剂中聚集体的研究, 高等学校化学学报, 1997, 第 1 作者

科研活动

   
科研项目
( 1 ) 抗光漂白有机红光染料的制备及其在活细胞成像中的应用研究, 负责人, 国家任务, 2016-01--2019-12
( 2 ) 多光子三维金属微纳结构加工基础研究, 参与, 国家任务, 2012-01--2015-12
( 3 ) EUV光刻胶材料配方工艺及放大研究, 参与, 国家任务, 2011-01--2013-12
( 4 ) 光驱动金属离子释放分子体系与反应机理, 负责人, 国家任务, 2011-01--2013-12
( 5 ) 多阶光存储记录材料与记录特性, 负责人, 地方任务, 2011-01--2012-12
( 6 ) 光子束超衍射纳米技术与应用基础研究, 参与, 国家任务, 2010-10--2014-09