基本信息
陈懿  女  博导  中国科学院理化技术研究所
电子邮件: yichen@mail.ipc.ac.cn
通信地址: 中国科学院理化技术研究所
邮政编码: 100190

招生信息

   
招生专业
070303-有机化学
招生方向
有机化学

教育背景

1993-09--中国科学院感光化学研究所   博士
1988-09--江西师范大学化学系   硕士
1982-09--江西师范大学化学系   学士

工作经历

   
工作简历
2004-01~现在, 中国科学院理化技术研究所, 研究员
2001-07~现在, 中国科学院理化技术研究所, 副研
2000-01~现在, 英国Oxford大学分子科学中心, 博士后
1997-01~现在, 英国Sunderland大学化学系, 博士后
1993-09~现在, 中国科学院感光化学研究所, 博士
1988-09~现在, 江西师范大学化学系, 硕士
1982-09~现在, 江西师范大学化学系, 学士

教授课程

有机光化学
光化学绿色合成与催化
有机光化学(二)
有机光化学(一)
有机光化学(一)

专利与奖励

   
专利成果
( 1 ) 一种抗绿脓杆菌的药物组合物及其制备方法和用途, 2021, 第 1 作者, 专利号: CN112294807A

( 2 ) 一种提高天然产物抗菌活性的联合体系及其应用, 2019, 第 1 作者, 专利号: CN109700803A

( 3 ) 一种氟原子取代的氰基异佛尔酮苯乙烯化合物、晶体化合物及制备方法, 2017, 第 1 作者, 专利号: CN106946739A

( 4 ) 提高脱水穿心莲内酯水溶性、酯-水分配系数的方法及新型脱水穿心莲内酯、制备、应用, 2017, 第 1 作者, 专利号: CN106467508A

( 5 ) 1,3,5-三(4-N,N’-二烷基苯胺)苯类有机化合物及其合成方法, 2014, 第 1 作者, 专利号: CN103524355A

( 6 ) 由3,4-二芳基-2,5-二氢噻吩合成3,4-二芳基噻吩的方法, 2012, 第 1 作者, 专利号: CN101318951B

( 7 ) 杂环取代的2,5-二氢吡咯类光致变色化合物及其合成方法和用途, 2006, 第 5 作者, 专利号: CN1250543C

( 8 ) 噁唑取代俘精酰亚胺类光致变色化合物及其合成方法和用途, 2006, 第 4 作者, 专利号: CN1239500C

( 9 ) 双杂环取代的俘精酸酐类光致变色化合物及其合成方法和用途, 2003, 第 3 作者, 专利号: CN1446878A

出版信息

   
发表论文
(1) Two-Photon Fluorescent Probes for Amyloid-β Plaques Imaging In Vivo, MOLECULES, 2023, 第 1 作者
(2) Two-photon AIEgen based on dicyanoisophorone derivative: Synthesis, characterization and cells imaging, JOURNAL OF MOLECULAR STRUCTURE, 2022, 通讯作者
(3) Recent advances in AIEgens for three-photon fluorescence bioimaging, MATERIALS TODAY CHEMISTRY, 2022, 
(4) Circularly polarized luminescence based on small organic fluorophores, MATERIALS TODAY CHEMISTRY, 2022, 
(5) Recent Advances in Excimer-Based Fluorescence Probes for Biological Applications, MOLECULES, 2022, 通讯作者
(6) Recent progress in fluorescent aptasensors for the detection of aflatoxin B1 in food, ANALYTICAL METHODS, 2022, 通讯作者
(7) Evaluation of Apigenin Inhibiting Lactate Dehydrogenase Activity Based on CdTe Quantum Dots Fluorescence, JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 2021, 通讯作者
(8) Nanoscale metal organic frameworks inhibition of pyruvate kinase of M2, Nanoscale metal organic frameworks inhibition of pyruvate kinase of M2, 中国化学快报:英文版, 2021, 第 6 作者
(9) Recent progress in natural product-based inhibitor screening with enzymatic fluorescent probes, ANALYTICAL METHODS, 2021, 通讯作者
(10) Recent advances in fluorescent probes for extracellular pH detection and imaging, ANALYTICAL BIOCHEMISTRY, 2021, 通讯作者
(11) Fluorescent probes for detection and bioimaging of leucine aminopeptidase, MATERIALS TODAY CHEMISTRY, 2020, 
(12) Advances in fluorescent probes for detection and imaging of endogenous tyrosinase activity, ANALYTICAL BIOCHEMISTRY, 2020, 通讯作者
(13) Recent developments of fluorescent probes for detection and bioimaging of nitric oxide, NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2020, 通讯作者
(14) Design and construction of COX-2 specific fluorescent probes, MOLECULAR AND CELLULAR PROBES, 2019, 通讯作者
(15) Two/multi-photon induced up-conversion emission of dicyanoisophorone derivative, JOURNAL OF PHOTOCHEMISTRY & PHOTOBIOLOGY, A: CHEMISTRY, 2018, 第 3 作者
(16) Two-photon induced excimer emission of dicyanoisophorone derivative in crystal state, JOURNAL OF LUMINESCENCE, 2018, 通讯作者
(17) Synthesis of 9,10-distyrylanthracene derivative and its one- and two-photon induced emission in solid state, JOURNAL OF PHOTOCHEMISTRY & PHOTOBIOLOGY, A: CHEMISTRY, 2018, 第 3 作者
(18) Two/multi-photon induced up-conversion emission of dicyanoisophorone derivative, JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2018, 通讯作者
(19) Synthesis of 9,10-distyrylanthracene derivative and its one- and two-photon induced emission in solid state, JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2018, 通讯作者
(20) An efficient photorelease of Zn2+ with turn-on fluorescence monitoring, JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2017, 通讯作者
(21) A fluorescent dye with large Stokes shift and high stability: synthesis and application to live cell imaging, RSC ADVANCES, 2017, 通讯作者
(22) One-pot synthesis of a near-infrared fluorophore for living cells imaging, DYES AND PIGMENTS, 2017, 通讯作者
(23) A fluorescent dye with large Stokes shift and high stability: synthesis and application to living cells imaging, RSC Adv, 2017, 通讯作者
(24) Oligo-polyethene glycol (PEG)-modified 14-deoxy-11,12-didehydroandrographolide derivatives: synthesis, solubility and anti-bacterial activity, TETRAHEDRON, 2016, 通讯作者
(25) Regio-selective pegylation of 14-deoxy-11,12-didehydroandrographolide and their biological evaluation, TETRAHEDRON, 2016, 通讯作者
(26) Excited-state intramolecular single and double proton transfer emission of 2,5-bis(benzoxazol-2-yl)thiophene-3,4-diol, DYES AND PIGMENTS, 2016, 通讯作者
(27) Two-photon pumped emission of polymeric thin film doped with dicyanopyranone derivative, RSC ADVANCES, 2015, 通讯作者
(28) Red fluorescence thin film based on a strong pushepull dicyanoisophorone system, Dyes and Pigments, 2015, 通讯作者
(29) Red fluorescence thin film based on a strong push–pull dicyanoisophorone system, DYES AND PIGMENTS, 2015, 通讯作者
(30) 2,5-双(对二甲氨基苯乙烯基)吡嗪的双光子诱导荧光性质, Two-photon-induced Fluorescence of 2,5-Bis (4-dimethylaminostyryl) pyrazine, 影像科学与光化学, 2015, 第 2 作者
(31) Synthesis of a water soluble red fluorescent dye and its application toliving cells imaging, DYES AND PIGMENTS, 2015, 通讯作者
(32) Photorelease of La3+ with turn-on fluorescent detection, JOURNAL OF PHOTOCHEMISTRY & PHOTOBIOLOGY, A: CHEMISTRY, 2014, 第 3 作者
(33) Photorelease of La3+ with turn-on fluorescent detection, JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2014, 通讯作者
(34) A highly stable and water-soluble fluorescent dye for fluorescence imaging of living cells, JOURNAL OF MATERIALS CHEMISTRY B, 2014, 通讯作者
(35) Photoactivatable turn-on fluorescence based on the photo-cleavage of the C-Br bond in 1,2-bis(5-(bromoethyl)benzoxazol-2-yl)ethane, NEW JOURNAL OF CHEMISTRY, 2014, 通讯作者
(36) Synthesis and fluorescence of dicyanoisophorone derivatives, DYES AND PIGMENTS, 2013, 通讯作者
(37) Synthesis and photophysical properties of thiolactone derivatives, TETRAHEDRON, 2013, 通讯作者
(38) Synthesis and fluorescence of dicyanoisophorone derivatives, DYES AND PIGMENTS, 2013, 通讯作者
(39) Force-induced cleavage of C–O bond in photochromic naphthopyrans, MATERIALS CHEMISTRY AND PHYSICS, 2013, 通讯作者
(40) Synthesis and photophysical properties of thiolactone derivatives, TETRAHEDRON, 2013, 通讯作者
(41) One-pot synthesis of N, N, N, N-tetraethyl-9H-xanthene-3,6-diamine and its conversion to pyronine B, DYES AND PIGMENTS, 2013, 通讯作者
(42) Selective photoconversion of photochromic diarylethenes and their properties, NEW JOURNAL OF CHEMISTRY, 2012, 通讯作者
(43) Photoconversion of a Protonated Diarylethene Derivative, JOURNAL OF PHYSICAL CHEMISTRY A, 2012, 通讯作者
(44) Modulation of absorption and fluorescence of photochromic diarylethene by intramolecular hydrogen bond, JOURNAL OF PHYSICAL ORGANIC CHEMISTRY, 2012, 通讯作者
(45) Photo-controlled metal-ion (Zn2+ and Cd2+) release in aqueous Tween-20 micelle solution, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2012, 通讯作者
(46) Mercury ion induced activation of the CeO bond in a photo-responsive spiropyran, Dyes and Pigments, 2011, 通讯作者
(47) Construction and Properties of a Phototriggered Cd2+ Release System, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2011, 通讯作者
(48) Modification of a photochromic 3-aryl-3-(a-naphthalene)-3H-naphtho[2,1-b] pyran system with a fast fading speed in solution and in a rigid polymer matrix, Journal of Materials Chemistry, 2011, 通讯作者
(49) Colorimetric probing of Hg2+ in both solution and thin film, ANALYTICAL METHODS, 2011, 通讯作者
(50) Modulation of color change and photocyclization of diarylethene with metal complex, JOURNAL OF PHYSICAL ORGANIC CHEMISTRY, 2011, 通讯作者
(51) 新型二芳基乙烯光致变色化合物的制备及其应用基础研究, 影像科学与光化学, 2011, 第 2 作者
(52) Mercury ion induced activation of the C-O bond in a photo-responsive spiropyran, DYES AND PIGMENTS, 2011, 通讯作者
(53) Construction of multi-level fluorescent switch using photochromic diarylethene and fluorescent dye, DYES AND PIGMENTS, 2011, 通讯作者
(54) Selective photochromism and solvatochromism of a diarylethene with different bridge units, JOURNAL OF MATERIALS CHEMISTRY, 2011, 通讯作者
(55) Modification of a photochromic 3-aryl-3-(alpha-naphthalene)-3H-naphtho2,1-bpyran system with a fast fading speed in solution and in a rigid polymer matrix, JOURNAL OF MATERIALS CHEMISTRY, 2011, 通讯作者
(56) Rapid fading of 3H-naphtho2,1-bpyrans with protonation of N,N-disubstituted group, JOURNAL OF MATERIALS CHEMISTRY, 2011, 通讯作者
(57) Carbon dioxide and water as a key for unlocking photochromism of diarylethene derivative, JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2010, 通讯作者
(58) A strategy for the design of photochromic naphthopyrans with large optical density at photosteady state and fast fading speed at ambient temperature in the dark, JOURNAL OF MATERIALS CHEMISTRY, 2010, 通讯作者
(59) Simple and rapid detection of aromatic amines using a thin layer chromatography plate, ANALYTICAL METHODS, 2010, 通讯作者
(60) 'locking and unlocking control' of photochromism of naphthopyran derivative, JOURNAL OF PHYSICAL ORGANIC CHEMISTRY, 2010, 通讯作者
(61) Photo-controlled zn2+ release system with dual binding-sites and turn-on fluorescence, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2010, 通讯作者
(62) Construction and properties of multi-addressable switching system based on a photochromic diarylethene, JOURNAL OF MATERIALS CHEMISTRY, 2009, 通讯作者
(63) Lewis acid and base triggered molecular switch, JOURNAL OF MATERIALS CHEMISTRY, 2009, 通讯作者
(64) The Photochromism and Fluorescence of Diarylethenes with a Imidazole Bridge Unit: A Strategy for the Design of Turn-on Fluorescent Diarylethene System, JOURNAL OF PHYSICAL CHEMISTRY A, 2009, 通讯作者
(65) A bifunctional metal probe with independent signal outputs and regulable detection limits, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2009, 通讯作者
(66) 光致变色二芳基乙烯抗疲劳特性实验研究, Experimental Measurement of Fatigue Resistance of a Photochromic Diarylethene, 光子学报, 2009, 第 5 作者
(67) Phototriggered metal-ion release from phenolic schiff bases: a system for metal-ion photodelivery, CHEMPHYSCHEM, 2009, 通讯作者
(68) Kinetic characterization of photoinduced anisotropy in diarylethene film, OPTICS COMMUNICATIONS, 2009, 第 5 作者
(69) Photochromic Properties of Naphthopyrans - PMMA Thin Film, MOLECULAR CRYSTALS AND LIQUID CRYSTALS, 2009, 通讯作者
(70) A light-modulated chemosensor for methanol with ratiometry and colorimetry, ANALYTICA CHIMICA ACTA, 2009, 通讯作者
(71) 二芳基乙烯光致各向异性动态特性研究, Dynamic properties of photoinduced anisotropy of diarylethene, 物理学报, 2008, 第 5 作者
(72) Dynamic properties of photoinduced anisotropy of diarylethene, ACTA PHYSICA SINICA, 2008, 第 5 作者
(73) Oxidation of 3,4-diaryl-2,5-dihydrothiophenes to 3,4-diarylthiophenes using CuBr2: Simple and efficient preparation of 3,4-diarylthiophenes, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2007, 第 2 作者
(74) Synthesis and photophysical properties of 1,4-bis(4,5-diarylimidazol) benzene dyes, JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2007, 通讯作者
(75) Electrochemical switch based on the photoisomerization of a diarylethene derivative, JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 2007, 通讯作者
(76) One-pot oxidation and bromination of 3,4-diaryl-2,5-dihydrothiophenes using Br-2: Synthesis and application of 3,4-diaryl-2,5-dibromothiophenes, JOURNAL OF ORGANIC CHEMISTRY, 2007, 通讯作者
(77) A selective, fluorescent probe for Hg2+ detection in aqueous solution, JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2007, 通讯作者
(78) Construction and photoswitching properties of fluorescent diarylethenes, JOURNAL OF MATERIALS CHEMISTRY, 2007, 通讯作者
(79) Combination of fluorescent switch and electrochemical switch based on a photochromic diarylethene, NEW JOURNAL OF CHEMISTRY, 2006, 通讯作者
(80) 双色俘精酸酐薄膜的双波长图像光存储, 光学学报, 2005, 第 3 作者
(81) 含S,N杂环戊烯桥头的二芳烯光致变色化合物的合成及性质研究, Synthesis and Properties of Diarylethenes with S, N-Hetercyclopentene Bridging Units, 感光科学与光化学, 2005, 第 2 作者
(82) 吡咯俘精酸酐的光致各向异性研究, Photoinduced Anisotropy in Pyrrylfulgide/PMMA Film, 光子学报, 2004, 第 8 作者
(83) 吲哚俘精酰胺的偏振全息图像光存储实验研究, Polarization holographic image storage with indolylfulgimide, 物理学报, 2004, 第 3 作者
(84) 有机光致变色材料——吡咯俘精酸酐的并行光存储实验, 科学通报, 2003, 第 3 作者
(85) 共轭读出法消除光致变色材料全息记录中的相位畸变, Phase Aberration Correction Using Conjugated Wave Reconstruction in Holography of Photochromic Material, 光子学报, 2003, 第 3 作者
(86) 光敏变色双呋喃俘精酸酐的合成及其在平行图象存储中的应用, 中国科学:B辑, 2003, 第 2 作者
(87) 光致变色双呋喃俘精酸酐的合成及其在平行图像存储中的应用, 中国科学. B辑, 化学, 2003, 第 2 作者
(88) 可擦写俘精酸酐/PMMA薄膜的全息记录特性研究, 光子学报, 2003, 第 7 作者
(89) 吡咯俘精酸酐的图像光存储特性, Optical Image Storage Using Pyrryl Fulgide, 光学学报, 2003, 第 8 作者
(90) 双光子光化学, Development of Twophoton-photochemistry Development, 山西大学学报:自然科学版, 2002, 第 4 作者
(91) 氧Weng盐分子在受限制体系中的电荷转移和发光行为, 感光科学与光化学, 1997, 第 1 作者
(92) 室温下氧Wong盐非极性溶剂中聚集体的研究, 高等学校化学学报, 1997, 第 1 作者

科研活动

   
科研项目
( 1 ) 光子束超衍射纳米技术与应用基础研究, 参与, 国家任务, 2010-10--2014-09
( 2 ) EUV光刻胶材料配方工艺及放大研究, 参与, 国家任务, 2011-01--2013-12
( 3 ) 多光子三维金属微纳结构加工基础研究, 参与, 国家任务, 2012-01--2015-12
( 4 ) 光驱动金属离子释放分子体系与反应机理, 负责人, 国家任务, 2011-01--2013-12
( 5 ) 多阶光存储记录材料与记录特性, 负责人, 地方任务, 2011-01--2012-12
( 6 ) 抗光漂白有机红光染料的制备及其在活细胞成像中的应用研究, 负责人, 国家任务, 2016-01--2019-12