General
Ying Zhang 
Email: zhangying@dicp.ac.cn
Telephone: 86-411-84379139
Address:  457 Zhongshan Road , Dalian 
Postcode: 116023

Research Areas

Biochemical engineering

Education

• B.S 1991.09 – 1995.07 Beijing University of Chemical Technology
 • Ph.D2001.09  2007. 05  Dalian Institute of Chemical Physics, Chinese
Academy of Sciences

Experience

   
Work Experience
Associate Professor in DICP, 
2011.10; Assistant Professor in DICP, 2007.11~2011.09

Publications

   
Papers

1 Ying Zhang, Wei Wang, etc. In vivo culture of encapsulated endostatin-CHO cells for systemic tumor inhibition. Human Gene Therapy. 18 (5): 474-481, 2007.

2 Ying Zhang, Wei Wang, etc. Tumor Anti-angiogenic Gene Therapy with Microencapsulated Recombinant CHO Cells. Annals of Biomedical Engineering. 35 (4): 605-614, 2007.

3 Ying Zhang, Wei Wang, etc. Optimization of Microencapsulated Recombinant CHO Cell Growth, Endostatin Production and Stability of Microcapsule in vivo. J Biomed Mater Res Part B: Appl Biomater 84B: 79-88, 2008.

4 Ying Zhang, Jing Zhou, etc. Optimization of the Seeding Density in Microencapsulated Recombinant CHO Cell Culture. Chem. Biochem. Eng. Q. 22 (1) : 105-111, 2008.

5 Qi Wen tao, Zhang Ying, etc. Optimization of the cell seeding density and modeling of cell growth and metabolism using themodified Gompertz model for microencapsulated animal cell culture. Biotechnology and Bioengineering. (93): 887-895, 2006.

6 Huaining Teng, Ying Zhang, etc. Inhibition of Tumor Growth in Mice by Endostatin Derived from Abdominal Transplanted Encapsulated Cell. Acta Biochim Biophys Sinica. 39 (4): 278-284, 2007.

7 Li N, Zhang Y*, Xiu ZL, Wang Y, Chen L, Wang SJ, Guo X, Ma XJ*.Thepreservation of islet with alginate encapsulation in the process of transportation. Biotechnology and Applied Biochemistry. 2015, 62 (4): 530-536.

8 Li N, Zhang Y*, Liu Y, Xiu ZL, Tan MQ, Li S, Guo X, Wang Y, Chen L, Song YZ, Yu WT, Lv GJ, Ma XJ*. Improvedislet purity by the hypertonic-hypotonic method. International Journal of Artificial Organs. 2015,37 (6): 477-485.

9 Li S, Zhang Y*, Chen L, Li N, Xie HG, Guo X, Zhao S, Yu WT, Lv Y, Lv GJ, Wu HJ*, Ma XJ. The relationship between the inflammatory response and cell adhesion on alginate-chitosan-alginate microcapsules after transplantation. Journal of biomedical materials research part A. 2015,103 (7): 2333-2343.

10 Deng F, Chen L, Zhang Y*, Zhao S, Wang Y, Li N, Li S, Guo X, Ma XJ. Development of a bioreactor based on magnetically stabilized fluidized bed for bioartificial liver. Bioprocess and biosystems engineering. 2015, 38 (12): 2369-2377.

11  Wang Y, Zhang Y*, Li N, Chen L, Zhang DM, Sun DS, Lv GJ, Yu WT, Guo X, Ma XJ*. Growth and Production of Microencapsulated recombinant CHO in a stirred tank bioreactor. Bioprocess and biosystems engineering. 2015,38 (7): 1303-1312.

12 Wang Y, Zhang Y*, Li N, Chen L, Zhang DM, Sun DS, Li S, Guo X, Ma XJ*. Stirring rate regulates the proliferation and metabolism of microencapsulated recombinant CHO cells. Biotechnology and  Applied Biochemistry.  2015, 62  (6): 833-839.

13 Huang PY, Zhang LD, Gao YM, He ZY, Yao D, Wu ZT, Cen J, Chen XT, Liu CC, Hu YP, Lai DM, Hu ZL, Chen L, Zhang Y, Cheng X, Ma XJ, Pan GY, Wang X, Hui LJ*. Direct Reprogramming of Human Fibroblasts to Functional and Expandable Hepatocytes. Cell Stem Cell. 2014,14: 370-384.

14 Chen L, Zhang Y*, Li S, Li N, Wang Y, Guo X, Zhao S, Yu WT, Sun GW, Liu Y, Ma XJ*. Effect of plasma components on the stability and permeability of microcapsule. Journal of Biomedical Materials Research: Part A. 2014, 102(7):  2408-2416.

15 Zhao W, Zhang Y*, Liu Y, Tan  MQ, Yu WT, Xie HG, Ma Ying, Sun GW, Lv  GJ, Zhao S, Ma XJ*. Oxygen diffusivity in alginate/chitosan microcapsules. Journal of Chemical Technology and Biotechnology. 2013, 88(3): 449-455.

16 Ma Y, Zhang Y*, Liu Y, Chen L, Zhao W, Sun GW, Li N, Wang Y, Guo X, Lv GJ, Ma XJ*. Investigation of alginate–ϵ-poly-L- lysine microcapsules for cell microencapsulation. Journal of  Biomedical Materials Research Part A. 2013, 101A (5): 1265-1273.

17 Ma Y, Zhang Y*, Wang Y, Wang QY, Tan MQ, Liu Y, Chen L, Li N, Yu WT, Ma XJ*. Study of the effect of membrane thickness on microcapsule strength, permeability, and cell proliferation. Journal of Biomedical Materials Research PartA. 2013,101A (4): 1007-1015.

18 Ma Y, Zhang Y*, Zhao S, Wang Y, Wang SR, Zhou Y, Li N, Xie HG, Yu WT, Liu Y, Wang W, Ma XJ*. Modeling and optimization of membrane preparation conditions of the alginate-based microcapsules with response surface methodology. Journal of Biomedical Materials Research Part A. 2012, 100A (4): 989-998.

19 Yu WTSong HYZheng GS Liu XD Zhang YMa XJ*. Study on membrane characteristics of alginate-chitosan microcapsule with cell growth. Journal of Membrane Science. 2011,337: 214-220.


Research Interests

Large scale culture of mammal cell, resarch of bioartificial liver