Environmental analysis,  biosensor, sensor, chromatography-mass spectrometry, 
electrochemistry, electroanalysis, wearable device, rapid detection method
1. Electrochemical biosensors and rapid detection method
 Research and development of new nano-sensing materials,  exploitation  of miniaturized portable electrochemical sensors and biosensors, flexible devices and  methods for rapid detection of target objects. Developing biosensors and wearable devices such as enzyme sensors, nucleic acid sensors, nuclear receptor sensors and immunosensors  for the rapid detection and toxicity assessment of important targets in the fields of environmental protection, food safety, life and health.
2. Chromatography-mass spectrometry & Trace analysis   
 Developing analytical methods and equipments based on chromatography-mass spectrometry for high sensitivity target analysis and high through non-target screening,  Analytical and separation materials, Effect directed analysis, etc. Studying the environmental monitoring method, migration and transformation, bioaccumulation, toxic effects and health risks of persistent organic pollutants and new pollutants, etc.

• 2007.6-2009.10, Environment Assessment and Analysis Group (103 Group), Dalian Institute of Chemical Physics (DICP), CAS, Assistant Professor;
• 2009.10-2014.6, DICP, CAS, Associate Professor, Dalian, Liaoning Province;
• 2013.2-2014.2, University of California, Los Angeles, Visiting scholar, U.S.A.
• 2014.6-present, DICP, CAS, Professor

• First Prize of the China Analytical and Testing Association Science and Technology Award (CAIA), 2022;
• The MDPI Outstanding Contribution Award, 2022; 
• Second Prize of Science and Technology Progress Award, from the Government of Liaoning province, 2016;
• "First Award of Natural Science" from the Chinese Ministry of Education, 2013; 
• "Second Award of Environmental protection science and Technology" from Environmental Protection Administration of China, 2014;  
• First Prize of “Technology Invention Award”, from the Government of Dalian, 2014;
• "Science and Technology Progress Award" from the Measurement and Testing Institute of China,2014;
• "Lujiaxi Young Talent Award" of the Chinese Academy of Sciences, 2013; 
• Second Prize of Natural Science Academic Achievement, Liaoning Province Association for science and technology, 2012 ;
• Member of &Youth Innovation Promotion Association，CAS, 2012-2015;
• Youth Award of Excellence, the Knowledge Innovation Program of CAS, 2010; 
• Second prize of excellent academic thesis of Natural Science, Dalian Association for science and technology, 2012;

REPRESENTATIVE PUBLICATIONS:

Mengqiong Zhang, Guowen Wang, Jiping Chen, Xianbo Lu*. Single Atom Catalysts for Sensors, Trends in Analytical Chemistry, 2023, 169, 117399.

Kai Niu, Jiping Chen, Xianbo Lu*, Versatile biomimetic catalyst functionalized nanozymes for electrochemical sensing. Chemical Engineering Journal, 2023, 475, 146491. 

Pengcheng Sun, Kai Niu, Haiying Du*, Ruixin Li, Jiping Chen, Xianbo Lu*，Ultrasensitive Rapid Detection of Antibiotic Resistance Genes by Electrochemical Ratiometric Genosensor Based on 2D Monolayer Ti₃C₂@AuNPs，Biosensors and Bioelectronics, 2023, 240, 115643.

Wu, L.; Lu, X.; Wu, Y.; Huang, C.; Gu, C.; Tian, Y.; Ma, J., An electrochemical sensor based on synergistic enhancement effects between nitrogen-doped carbon nanotubes and copper ions for ultrasensitive determination of anti-diabetic metformin. The Science of the total environment 2023, 163120.

Kai Niu, Pengcheng Sun, Jiping Chen, Xianbo Lu*, Dense Conductive Metal-Organic Frameworks as Robust Electrocatalyst for Biosensing. Analytical Chemistry, 2022, 94, 17177–17185. https://doi.org/10.1021/acs.analchem.2c03766.

Kai Niu, Yuying Zhang, Jiping Chen，Xianbo Lu*, 2D Conductive Covalent Organic Frameworks with Abundant Carbonyl Groups for Electrochemical Sensing, ACS Sensors, 2022, 7, 3551–3559. https://doi.org/10.1021/acssensors.2c02014.

Kai Niu, Zicheng Zuo, Xianbo Lu*, Lili Zou, Jiping Chen，Ultrathin graphdiyne nanosheets confining Cu quantum dots as robust electrocatalyst for biosensing featuring remarkably enhanced activity and stability. Biosensors and Bioelectronics 2022, 205,114111. https://doi.org/10.1016/j.bios.2022.114111  

Pengcheng Sun, Kai Niu, Haiying Du *, Ruixin Li , Jiping Chen, and Xianbo Lu*, Sensitive Electrochemical Biosensor for Rapid Screening of Tumor Biomarker TP53 Gene Mutation Hotspot. Biosensors, 2022, 12, 658.

Kai Niu, Juan Gao, Lingxia Wu, Xianbo Lu,* Jiping Chen, Nitrogen-doped Graphdiyne as a Robust Electrochemical Biosensing Platform for Ultrasensitive Detection of Environmental Pollutants. Analytical Chemistry, 2021, https://doi.org/10.1021/acs.analchem.1c01800

Shuai Sun, Rong Cao, Jing Jin, Yichi Zhang, Yuan Gao, Xianbo Lu, Jiping Chen, Haijun Zhang, Accumulation characteristics and estimated dietary intakes of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and polychlorinated biphenyls in plant-origin foodstuffs from Chinese markets. Science of the Total Environment, 2021,775,145830.

Shuai Sun, Rong Cao, Xianbo Lu, Yichi Zhang, Yuan Gao, Jiping Chen, Haijun Zhang, Levels and patterns of polychlorinated dibenzo-p-dioxins and dibenzofurans and polychlorinated biphenyls in foodstuffs of animal origin from Chinese markets and implications of dietary exposure. Environmental Pollution, 2021, 273, 116344.

Wu, L.;Lu, X.;*Niu, K.; Dhanjai; Chen, J., Tyrosinase nanocapsule based nano-biosensor for ultrasensitive and rapid detection of bisphenol A with excellent stability in different application scenarios.Biosens Bioelectron2020,165, 112407.

Wu, L.; Gao, J.;Lu, X.;*Huang, C.; Dhanjai; Chen, J., Graphdiyne: A new promising member of 2D all-carbon nanomaterial as robust electrochemical enzyme biosensor platform.Carbon2020,156, 568-575.

Dhanjai;Lu, X.;*Wu, L.; Chen, J.; Lu, Y., Robust Single-Molecule Enzyme Nanocapsules for Biosensing with Significantly Improved Biosensor Stability.Analytical Chemistry2020,92(8), 5830-5837.

Tan, J.;Lu, X.;*Fu, L.; Yang, G.; Chen, J., Quantification of Cl-PAHs and their parent compounds in fish by improved ASE method and stable isotope dilution GC-MS.Ecotoxicology and Environmental Safety2019,186.

Tan, D.; Jin, J.; Wang, L.; He, X.; Guo, C.; Dhanjai;Lu, X.;*Chen, J., Quantification of bisphenol A and its selected analogs in serum using pre-column derivatization with high-performance liquid chromatography and tandem mass spectrometry.Journal of Separation Science2019,42(5), 991-998.

Fu, L.;Lu, X.;*Niu, K.; Tan, J.; Chen, J., Bioaccumulation and human health implications of essential and toxic metals in freshwater products of Northeast China.Science of the Total Environment2019,673, 768-776.

Dhanjai; Balla, P.; Sinha, A.; Wu, L.;Lu, X.;*Tan, D.; Chen, J., Co3O4 nanoparticles supported mesoporous carbon framework interface for glucose biosensing.Talanta2019,203, 112-121.

Wu, L.;Lu, X.;*Dhanjai; Wu, Z.-S.; Dong, Y.; Wang, X.; Zheng, S.; Chen, J., 2D transition metal carbide MXene as a robust biosensing platform for enzyme immobilization and ultrasensitive detection of phenol.Biosensors & Bioelectronics2018,107, 69-75.

Tan, D.; Jin, J.; Wang, L.; Zhao, X.; Guo, C.; Sun, X.; Dhanjai;Lu, X.;Chen, J., Ammonium hydroxide enhancing electrospray response and boosting sensitivity of bisphenol A and its analogs.Talanta2018,182, 590-594.

Sinha, A.; Dhanjai; Zhao, H.; Huang, Y.;Lu, X.;*Chen, J.; Jain, R., MXene: An emerging material for sensing and biosensing.Trac-Trends in Analytical Chemistry2018,105, 424-435.

Fu, L.;Lu, X.;*Tan, J.; Zhang, H.; Zhang, Y.; Wang, S.; Chen, J., Bioaccumulation and human health risks of OCPs and PCBs in freshwater products of Northeast China.Environmental Pollution2018,242, 1527-1534.

Fu, L.;Lu, X.;*Tan, J.; Wang, L.; Chen, J., Multiresidue determination and potential risks of emerging pesticides in aquatic products from Northeast China by LC-MS/MS.Journal of Environmental Sciences2018,63, 116-125.

Dhanjai; Sinha, A.; Wu, L.;Lu, X.;*Chen, J.; Jain, R., Advances in sensing and biosensing of bisphenols: A review.Analytica Chimica Acta2018,998, 1-27.

Dhanjai; Sinha, A.; Wu, L.;Lu, X.;*Chen, J.; Jain, R., Advances in sensing and biosensing of bisphenols: A review (vol 998, pg 1, 2018).Analytica Chimica Acta2018,1029, 125-129.

Dhanjai; Sinha, A.;Lu, X.;*Wu, L.; Tan, D.; Li, Y.; Chen, J.; Jain, R., Voltammetric sensing of biomolecules at carbon based electrode interfaces: A review.Trac-Trends in Analytical Chemistry2018,98, 174-189.

Wu, L.; Lu, X.;* Fu, X.; Wu, L.; Liu, H., Gold Nanoparticles dotted Reduction Graphene Oxide Nanocomposite Based Electrochemical Aptasensor for Selective, Rapid, Sensitive and Congener-Specific PCB77 Detection.Scientific Reports2017,7.

Das, R.; Vecitis, C. D.; Schulze, A.; Cao, B.; Ismail, A. F.;Lu, X.;Chen, J.; Ramakrishna, S., Recent advances in nanomaterials for water protection and monitoring.Chemical Society Reviews2017,46(22), 6946-7020.

Zhang, H.;Lu, X.;*Zhang, Y.; Ma, X.; Wang, S.; Ni, Y.; Chen, J., Bioaccumulation of organochlorine pesticides and polychlorinated biphenyls by loaches living in rice paddy fields of Northeast China.Environmental Pollution2016,216, 893-901.

Lu, X.;*Wang, X.; Wu, L.; Wu, L.; Dhanjai; Fu, L.; Gao, Y.; Chen, J.*, Response Characteristics of Bisphenols on a Metal-Organic Framework-Based Tyrosinase Nanosensor.Acs Applied Materials & Interfaces2016,8(25), 16533-16539.

Gao, Y.; Zhang, H.; Zou, L.; Wu, P.; Yu, Z.;Lu, X.;Chen, J., Quantification of Short-Chain Chlorinated Paraffins by Deuterodechlorination Combined with Gas Chromatography-Mass Spectrometry.Environmental Science & Technology2016,50(7), 3746-3753.

Wu, L.;Lu, X.;*Wang, X.; Song, Y.; Chen, J., An electrochemical deoxyribonucleic acid biosensor for rapid genotoxicity screening of chemicals.Analytical Methods2015,7(8), 3347-3352.

Wang, X.;Lu, X.;*Wu, L.; Chen, J.,* 3D metal-organic framework as highly efficient biosensing platform for ultrasensitive and rapid detection of bisphenol A.Biosensors & Bioelectronics2015,65, 295-301.

Wang, X.;Lu, X.;*Wu, L.; Chen, J., Direct Electrochemical Tyrosinase Biosensor based on Mesoporous Carbon and Co3O4 Nanorods for the Rapid Detection of Phenolic Pollutants.Chemelectrochem2014,1(4), 808-816.

Wang, X.;Lu, X.;Chen, J., Development of biosensor technologies for analysis of environmental contaminants.Trends in Environmental Analytical Chemistry2014,2, 25-32.

Lu, X.;*Wang, X.; Jin, J.; Zhang, Q.; Chen, J.,* Electrochemical biosensing platform based on amino acid ionic liquid functionalized graphene for ultrasensitive biosensing applications.Biosensors & Bioelectronics2014,62, 134-139.

Teng, M.; Zhang, H.; Fu, Q.; Lu, X.;* Chen, J.; Wei, F., Irrigation-induced pollution of organochlorine pesticides and polychlorinated biphenyls in paddy field ecosystem of Liaohe River Plain, China.Chinese Science Bulletin2013,58(15), 1751-1759.

Wu, L.;Lu, X.;*Zhang, H.; Chen, J., Amino Acid Ionic Liquid Modified Mesoporous Carbon: A Tailor-made Nanostructure Biosensing Platform.Chemsuschem2012,5(10), 1918-1925.

Wu, L.; Deng, D.; Jin, J.;Lu, X.;*Chen, J.,* Nano-graphene-based tyrosinase biosensor for rapid detection of bisphenol A.Biosensors & Bioelectronics2012,35(1), 193-199.

Lu, X.;* Chen, J.; Wang, S.; Zou, L.; Tian, Y.; Ni, Y.; Su, F., Preparation and certification of mussel reference material for organochlorine pesticides and polychlorinated biphenyls using isotope dilution-high resolution mass spectrometry.Se pu = Chinese journal of chromatography2012,30(9), 915-21.

Zhao, X.; Zhang, H.; Ni, Y.; Lu, X.; Zhang, X.; Su, F.; Fan, J.; Guan, D.; Chen, J., Polybrominated diphenyl ethers in sediments of the Daliao River Estuary, China: Levels, distribution and their influencing factors.Chemosphere2011,82(9), 1262-1267.

Wu, L.;Lu, X.;*Jin, J.; Zhang, H.; Chen, J., Electrochemical DNA biosensor for screening of chlorinated benzene pollutants.Biosensors & Bioelectronics2011,26(10), 4040-4045.

 Jin, J.; Zhang, Z.; Li, Y.; Lu, X.; Wu, L.; Chen, J., Preparation, characterization and application of octadecyl modified magnesium oxide microspheres.Analytica Chimica Acta2011,693(1-2), 54-61.

Jin, J.; Li, Y.; Zhang, Z.; Su, F.; Qi, P.;Lu, X.;Chen, J., The selective cleanup of complex matrices and simultaneous separation of benzo a pyrene by solid-phase extraction with MgO microspheres as sorbents.Journal of Chromatography A2011,1218(51), 9149-9154.

Fan, Y.;Lu, X.;Ni, Y.; Zhang, H.; Zhu, M.; Li, Y.; Chen, J., Catalytic destruction of chlorinated aromatic pollutants over mesoporous CuxMg1-xAl2O4 spinel oxides.Applied Catalysis B-Environmental2011,101(3-4), 606-612.

Zhu, H.-Y.; Lu, X.-B.; Tian, Y.-Z.; Chen, J.-P., Phosphonium Ionic Liquids as Stationary Phases in Gas Chromatography.Chinese Journal of Analytical Chemistry2010,38(7), 1003-1006.

 Zhu, H.; Lu, X.; Tang, F.; Chen, J., Progress of the application of ionic liquid in stationary phase of gas chromatography.Metallurgical Analysis2010,30(7), 24-29.

37.   Zhang, H.; Zhao, X.; Ni, Y.; Lu, X.; Chen, J.; Su, F.; Zhao, L.; Zhang, N.; Zhang, X., PCDD/Fs and PCBs in sediments of the Liaohe River, China: Levels, distribution, and possible sources.Chemosphere2010,79(7), 754-762.

Zhang, H.; Zhao, S.; Yu, Y.; Ni, Y.;Lu, X.; Tian, Y.; Chen, J., Retention of Nonionic Organic Compounds on Thermally Treated Soils.Environmental Science & Technology2010,44(10), 3677-3682.

 Jin, J.; Zhang, Z.; Li, Y.; Qi, P.; Lu, X.; Wang, J.; Chen, J.; Su, F., Enrichment of polycyclic aromatic hydrocarbons in seawater with magnesium oxide microspheres as a solid-phase extraction sorbent.Analytica Chimica Acta2010,678(2), 183-188.

Fan, Y.; Lu, X.; Ni, Y.; Zhang, H.; Zhao, L.; Chen, J.; Sun, C., Destruction of Polychlorinated Aromatic Compounds by Spinel-Type Complex Oxides.Environmental Science & Technology2010,44(8), 3079-3084.

Lu, X.; Xiao, Y.; Lei, Z.; Chen, J.; Zhang, H.; Ni, Y.; Zhang, Q., A promising electrochemical biosensing platform based on graphitized ordered mesoporous carbon.Journal of Materials Chemistry2009,19(27), 4707-4714.

Lu, X.; Xiao, Y.; Lei, Z.; Chen, J., Graphitized macroporous carbon microarray with hierarchical mesopores as host for the fabrication of electrochemical biosensor.Biosensors & Bioelectronics2009,25(1), 244-247.

Jin, J.; Zhang, Z.; Ma, H.; Lu, X.; Chen, J.; Zhang, Q.; Zhang, H.; Ni, Y., Surface modification of spherical magnesium oxide with ethylene glycol.Materials Letters2009,63(17), 1514-1516.

Zhang, H.; Ni, Y.; Chen, J.; Su, F.; Lu, X.; Zhao, L.; Zhang, Q.; Zhang, X., Polychlorinated dibenzo-p-dioxins and dibenzofurans in soils and sediments from Daliao River Basin, China.Chemosphere2008,73(10), 1640-1648.

Lu, X.; Zhou, J.; Zhao, Y.; Qiu, Y.; Li, J., Room temperature ionic liquid based polystyrene nanofibers with superhydrophobicity and conductivity produced by electrospinning.Chemistry of Materials2008,20(10), 3420-3424.

Lu, X.; Zhou, J.; Lu, W.; Liu, Q.; Li, J., Carbon nanofiber-based composites for the construction of mediator-free biosensors.Biosensors & Bioelectronics2008,23(8), 1236-1243.

Lu, X.; Zhang, H.; Ni, Y.; Zhang, Q.; Chen, J., Porous nanosheet-based ZnO microspheres for the construction of direct electrochemical biosensors.Biosensors & Bioelectronics2008,24(1), 93-98.

Zhou, J.; Lu, X.; Hu, J.; Li, J., Reversible immobilization and direct electron transfer of cytochrome c on a pH-sensitive polymer interface.Chemistry-a European Journal2007,13(10), 2847-2853.

 Zhou, J.; Liu, J.; Wang, G.; Lu, X.; Wen, Z.; Li, J., Poly(N-isopropylacrylamide) interfaces with dissimilar thermo-responsive behavior for controlling ion permeation and immobilization.Advanced Functional Materials2007,17(16), 3377-3382.

Zhang, Q.; Zhang, L.; Liu, B.; Lu, X.; Li, J., Assembly of quantum dots-mesoporous silicate hybrid material for protein immobilization and direct electrochemistry.Biosensors & Bioelectronics2007,23(5), 695-700.

 Zhang, L.; Zhang, Q.; Lu, X.; Li, J., Direct electrochemistry and electrocatalysis based on film of horseradish peroxidase intercalated into layered titanate nano-sheets.Biosensors & Bioelectronics2007,23(1), 102-106.

  Lu, X.; Zou, G.; Li, J., Hemoglobin entrapped within a layered spongy Co3O4 based nanocomposite featuring direct electron transfer and peroxidase activity.Journal of Materials Chemistry2007,17(14), 1427-1432.

 Liu, Q.; Lu, X.; Li, J.; Yao, X.; Li, J., Direct electrochemistry of glucose oxidase and electrochemical biosensing of glucose on quantum dots/carbon nanotubes electrodes.Biosensors & Bioelectronics2007,22(12), 3203-3209.

 Zhou, J.; Wang, G.; Hu, J.; Lu, X.; Li, J., Temperature, ionic strength and pH induced electrochemical switching of smart polymer interfaces.Chemical Communications 2006, (46), 4820-4822.

 Lu, X. B.; Hu, J. Q.; Yao, X.; Wang, Z. P.; Li, J. H., Composite system based on chitosan and room-temperature ionic liquid: Direct electrochemistry and electrocatalysis of hemoglobin.Biomacromolecules 2006,7(3), 975-980.

  Lu, X.; Zhang, Q.; Zhang, L.; Li, J., Direct electron transfer of horseradish peroxidase and its biosensor based on chitosan and room temperature ionic liquid.Electrochemistry Communications 2006,8(5), 874-878.

  Lu, X.; Wen, Z.; Li, J., Hydroxyl-containing antimony oxide bromide nanorods combined with chitosan for biosensors.Biomaterials 2006,27(33), 5740-5747.

Lu, X. B.; Wu, S. G.; Wang, L.; Su, Z. X., Solid-state amperometric hydrogen sensor based on polymer electrolyte membrane fuel cell.Sensors and Actuators B-Chemical 2005,107(2), 812

Dr. Lu holds more than 10 authorized invention patents.

Dhanjai*, Ankita Sinha, Samuel M. Mugo, Xianbo Lu*, Jiping Chen*, Molecular imprinted polymer-based biosensors for the detection of pharmaceutical contaminants in the environment, Elsevier Inc., Tools, Techniques and Protocols for Monitoring Environmental Contaminants, Chapter 17, 2019: p371-389.

Hu, Jianqiang; Liu, Juan; Lu, Xianbo; Lu, Wu; Zhou, Jianhua ; Li, Jinghong; editor:Carlson, ED, “THREE-DIMENSIONAL CONTROLLABLE SUBMICRON GOLD FILMS: SULFHYDRYL-CONTAINING MOLECULAR ASSEMBLY AND CONTROLLABLE SURFACE PLASMON RESONANCE AND ELECTROCATALYSIS PROPERTIES”, ENCYCLOPEDIA OF NANOTECHNOLOGY, VOLS 1 AND 2, 2009: 547-560