基本信息
卢宪波  男  博导  中国科学院大连化学物理研究所
电子邮件: xianbolu@dicp.ac.cn
通信地址: 大连市中山路457号生物楼103组
邮政编码: 116023

研究领域

   主要瞄准国家在生态环境、食品安全和生命健康领域的战略需求开展快速检测与痕量分析监测技术与设备研发。主要研究方向:


1.  生物传感器与快检方法

   研发新型纳米传感材料,研究纳米生物电化学,研制用于目标快速筛查和​效应评估的生物传感器与配套方法。研制用于环境、食品、体液中重要目标物快速筛查与检测的酶传感器、核酸传感器、微生物传感器和免疫传感器。

2. 色谱质谱与痕量分析

   针对复杂样品中痕量物质分析需求,研发基于色谱-质谱的高灵敏靶标检测方法和高通量非目标筛查方法,以及效应导向分析方法和样品前处理技术。研究持久性有机污染物和新型污染物的迁移转化、生物累积和健康风险。

3. 环境监测修复技术与设备

    研发地表和地下水、场地土壤、环境大气中重要目标物和关键指标监测技术与设备。开发与集成水质、土壤、大气中危害物修复关键技术与设备。



招生信息

欢迎化学、化工、环境、生物等相关专业的学生报考。

招生专业
070302-分析化学
070302-分析化学

教育背景

2005-02--2007-06   清华大学   博士研究生
2002-09--2007-06   中国科学技术大学   博士
学习简历

2002.9-2007.6 中国科学技术大学, 分析化学,博士 
2005.2-2007.6 清华大学,分析化学,  博士研究生

工作经历


2014.6-至今,中国科学院大连化学物理研究所,研究员。
2013.2-2014.2,美国加州大学洛杉矶分校(UCLA),公派访问学者。
2009.10-2014.6,中科院大连化学物理研究所,副研究员。 
2007.6-2009.9,中科院大连化学物理研究所,助理研究员。

学术兼职

2021-02-今,Biosensors,期刊编委

2020-12-今,中国环境科学学会POPs专委会, 委员

2018-12-今,  中国环境科学学会环境化学分会, 委员

科技奖励与个人荣誉


1.  辽宁省科技进步二等奖(2016年)
2.  国家环保部 环境保护科学技术奖二等奖 (2014年度)
3.  中科院卢嘉锡青年人才奖 (2013年) 
4.  大连市技术发明一等奖(2014年)
5.    教育部自然科学奖一等奖(2012年)
6.    中国计量测试学会科学技术进步奖(2014年度)
7.  大连化物所冠名奖-青年优秀奖(2010年) 
8.  辽宁省自然科学学术成果奖二等奖 (2012年) 
9.  大连市自然科学优秀学术论文二等奖(2012年,2015年)

出版信息

Kai Niu, Juan Gao, Lingxia Wu, Xianbo Lu,* Jiping Chen, Nitrogen-doped Graphdiyne as a Robust Electrochemical Biosensing Platform for Ultrasensitive Detection of Environmental Pollutants. Analytical Chemistry, 2021, https://doi.org/10.1021/acs.analchem.1c01800


Shuai Sun, Rong Cao, Jing Jin, Yichi Zhang, Yuan Gao, Xianbo Lu, Jiping Chen, Haijun Zhang, Accumulation characteristics and estimated dietary intakes of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and polychlorinated biphenyls in plant-origin foodstuffs from Chinese markets. Science of the Total Environment, 2021,775,145830.


Shuai Sun, Rong Cao, Xianbo Lu, Yichi Zhang, Yuan Gao, Jiping Chen, Haijun Zhang, Levels and patterns of polychlorinated dibenzo-p-dioxins and dibenzofurans and polychlorinated biphenyls in foodstuffs of animal origin from Chinese markets and implications of dietary exposure. Environmental Pollution, 2021, 273, 116344.


Dhanjai, Xianbo Lu*, Lingxia Wu, Jiping Chen, Yunfeng LuRobust Single Molecule Enzyme Nanocapsules for Electrochemical Biosensing with Significantly Improved Biosensor Stability, Analytical Chemistry, 2020, 92, 5830−5837.


Lingxia Wu, Xianbo Lu,* Kai Niu, Dhanjai, Jiping Chen. Tyrosinase nanocapsule based nano-biosensor for ultrasensitivity and rapid detection of bisphenol A with excellent stability in different application scenarios. Biosensors & Bioelectronics, 2020, 165, 112407.


Lingxia Wu, Juan Gao, Xianbo Lu,* Changshui Huang, Dhanjai, Jiping Chen, Graphdiyne: a new promising member of 2D all-carbon nanomaterial as robust electrochemical enzyme biosensor platform. Carbon, 2020, 156, 568-575.


Jun Tan, Xianbo Lu,*, Lei Fu, Guoshun Yang, Jiping Chen, Quantification of Cl-PAHs and their parent compounds in fish by improved ASE method and stable isotope dilution GC-MS, Ecotoxicology and Environmental Safety, 2019, 186, 109775.


Dhanjai*, Ankita Sinha, Samuel M. Mugo, Xianbo Lu*, Jiping Chen*, Molecular imprinted polymer-based biosensors for the detection of pharmaceutical contaminants in the environment, Elsevier Inc., Tools, Techniques and Protocols for Monitoring Environmental Contaminants, Chapter 17, 2019: p371-389.


Dhanjai, PutrakumarBalla, AnkitaSinha, LingxiaWu, XianboLu, DongqinTan, JipingChen, Co3O4 nanoparticles supported mesoporous carbon framework interface for glucose biosensing, Talanta, 2019, 203,112–121.


 Tan, Dongqin ; Jin, Jing ; Wang, Longxing ; He, Xiaolin; Guo, Cuicui; Dhanjai Dhanjai; Lu, Xianbo; Chen, Jiping, Quantification of bisphenol A and its selected analogs in serum using pre-column derivatization with high-performance liquid chromatography and tandem mass spectrometry, JOURNAL OF SEPARATION SCIENCE, 2019, 42, 991-998.


Lei Fu, Xianbo Lu,* Kai Niu, Jun Tan, Jiping Chen, Bioaccumulation and human health implications of essential and toxic metals in freshwater products of Northeast China, Science of the Total Environment, 2019, 673, 768–776.


王金成,樊芸,卢宪波,张海军,陈吉平.固相萃取高效液相色谱法同时测定自来水中氯代多环芳烃和多环芳烃,环境化学201837(9), 19871993


A. Sinha, Dhanjai, H. Zhao, Y. Huang, Xianbo Lu, J. Chen, R. Jain, MXene: An Emerging Material for Sensing and Biosensing, TRAC-Trends in Analytical Chemistry, 2018, 105, 424-435.  


Lei Fu, Xianbo Lu*, Jun Tan, Haijun Zhang, Yichi Zhang, Shuqiu Wang, Jiping Chen, Bioaccumulation and human health risks of OCPs and PCBs in freshwater products of Northeast China, Environmental Pollution2018, 242, 1527-1534.


Lingxia Wu, Xianbo Lu*, Dhanjai, Zhongshuai Wu, Yanfeng Dong, Xiaohui Wang, Shuanghao Zheng, Jiping Chen, 2D transition metal carbide MXene as a robust biosensing platform for enzyme immobilization and ultrasensitive detection of phenolBiosensors and Bioelectronics, 2018, 107, 69–75.


Dhanjaia, Ankita Sinhab, Xianbo Lu,* Lingxia Wu, Dongqin Tan, Yun Li, Jiping Chen, Rajeev Jain, Voltammetric Sensing of Biomolecules at Carbon Based Electrode Interfaces: A Review, TRAC-Trends in Analytical Chemistry, 2018, 98, 174-189.


Dhanjai; Ankita Sinha; Lingxia Wu; Xianbo Lu;* Jiping Chen; Rajeev Jain, Advances in Sensing and Biosensing of Bisphenols: A Review, Analytica Chimica Acta, 2018, 998, 1-27.


Dongqin Tan, Jing Jin, Longxing Wang, Xueqin Zhao, Cuicui Guo, Xiaoli Sun, Dhanjai, Xianbo Lu, Jiping Chen, Ammonium hydroxide enhancing electrospray response and boosting sensitivity of bisphenol A and its analogs, Talanta, 2018, 182, 590–594.


Rasel Das, Chad D. Vecitis, Agnes Schulze, Bin Cao, Ahmad Fauzi Ismail, Xianbo Lu, Jiping Chen, Seeram Ramakrishna, Recent Advances of Nanomaterials for Water Protection and Monitoring, Chemical Society Reviews, 2017, 46, 6946-7020 


Zhang Y C, Zhang H J, Wang S Q, Gao Yuan, Lu Xianbo, Chen Jiping. Indicator role of zucchini (Cucurbita pepo L.) for the pollution levels of persistent organochlorines in soils. Asian Journal of Ecotoxicology, 2017, 12(4): 145-151


Lei Fu, Xianbo Lu,* Jun Tan, Longxing Wang, Jiping Chen, Multiresidue determination and potential risks of emerging pesticides in aquatic products from Northeast China by LC-MS/MS,Journal of Environmental Sciences, 2018, 63C116-125.


Lidong Wu, Xianbo Lu*, Xiaochen Fu, Lingxia Wu, Huan Liu. Gold Nanoparticles dotted Reduction Graphene Oxide Nanocomposite Based Electrochemical Aptasensor for Selective, Rapid, Sensitive and Congener-Specific PCB77 Detection. Scientific Reports, 2017, 7, 5191.


Haijun Zhang, Xianbo Lu, Yichi Zhang, Xindong Ma, Shuqiu Wang, Hongxu Tian, Jiping Chen, Bioaccumulation of Organochlorine Pesticides and Polychlorinated Biphenyls by Loaches Living in Rice Paddy Fields of Northeast China, Environmental Pollution2016, 216, 893-901.


 Xianbo Lu*, Xue Wang, Lidong Wu, Lingxia Wu, Dhanjai, Lei Fu, Yuan Gao, Jiping Chen*Response characteristics of bisphenols on metal-organic framework based tyrosinase nanosensor ACS Applied Materials & Interfaces, 2016, 8 (25), 16533–16539.


Yuan Gao, Haijun Zhang, Lili Zou, Ping Wu, Zhengkun Yu, Xianbo Lu, and Jiping Chen, Quantification of Short-Chain Chlorinated Paraffins by Deuterodechlorination Combined with Gas Chromatography-Mass Spectrometry, Environmental Science & Technology, 2016, 50, 3746–3753.


 Xue Wang,Xianbo Lu,*, Lidong Wu, Yi wang, Jiping Chen*, 3D Metal-Organic Framework as Highly Efficient Biosensing Platform for Ultrasensitive and Rapid Detection of Bisphenol A,Biosensors and Bioelectronics,2015, 65, 295-301.

Lidong Wu, Xianbo Lu*, Xue Wang, Yi Song, Jiping Chen*, An Electrochemical Deoxyribonucleic Acid Biosensor for Rapid Genotoxicity Screening of Chemicals, Analytical Methods, 2015, 7, 3347-3352.
Xianbo Lu*, Xue Wang, Jing Jin, Qing Zhang, Jiping Chen*, Electrochemical biosensing platform based on amino acid ionic liquid functionalized graphene for ultrasensitive biosensing applications. Biosensors and Bioelectronics 2014, 62, 134-139.

Xue Wang, Xianbo Lu, Jiping Chen, Development of biosensor technologies for analysis of environmental contaminants, Trends in Environmental Analytical Chemistry, 2014, 2, 25-32.

Xue Wang, Xianbo Lu*, Lidong Wu, Jiping Chen, Direct electrochemical tyrosinase biosensor based on mesoporous carbon and Co3O4 nanorods for rapid detection of phenolic pollutants. ChemElectroChem, 2014, 1, 808-816. 

 Lidong Wu, Xianbo Lu*, Haijun Zhang, Jiping Chen*, Amino Acid Ionic Liquid Modified Mesoporous Carbon: A New Tailor-made Nanostructure Biosensing Platform, Chemsuschem, 2012, 5, 1918-1925. 

Lidong Wu, Dehui Deng, Jing Jin, Xianbo Lu*, Jiping Chen. Nanographene-based Tyrosinase Biosensor for Rapid Detection of Bisphenol A, Biosensors and Bioelectronics, 2012, 35, 193-199. 

Lidong Wu, Xianbo Lu, Jing Jin, Haijun Zhang, Jiping Chen, Electrochemical DNA biosensor for screening of chlorinated benzenepollutants. Biosensors and Bioelectronics, 2011, 26, 4040-4045. 

Yun Fan, Xianbo Lu, Yuwen Ni, Haijun Zhang, Meiwen Zhu, Yun Li and Jiping Chen, Catalytic destruction of chlorinated aromatic pollutants over mesoporous CuxMg1-xAl2O4 spinel oxides , Applied Catalysis B: Environmental, 2011, 101, 606-612. 

YunFan, Xianbo Lu, Yuwen Ni, Haijun Zhang, Liangzhang, Jiping Chen, ChenlinSun. Destruction of Polychlorinated Aromatic Compounds by Spinel-Type Complex Oxides. Environ. Sci. Technol. 2010, 44, 3079-3084. 

Xianbo Lu, Yi Xiao, Zhibin Lei, Jiping Chen*, Haijun Zhang, Yuwen Ni, Qing Zhang. A promising electrochemical biosensing platform based on graphitized ordered mesoporous carbon. Journal of Materials Chemistry, 2009, 19, 4707-4714. 

Xianbo Lu, Jiping Chen*, et al., Graphitized macroporous carbon microarray with hierarchical mesopores as host for the fabrication of electrochemical biosensor. Biosensors and Bioelectronics. 2009, 25, 244-247. 

Xianbo Lu, Haijun Zhang, Yuwen Ni, Qing Zhang, Jiping Chen*,Porous nanosheet-based ZnO microspheres for the construction of direct electrochemical biosensors. Biosensors and Bioelectronics. 2008, 24, 93-98. 

Xianbo Lu, Jianhua Zhou, et al.,“Room temperature ionic liquid based polystyrene nanofibers with superhydrophobility and conductivity produced by electrospinning Chem. Mater. 2008, 20, 3420-3424. 

Xianbo Lu, Jianhua Zhou, Wu Lu, Qing Liu, Jinghong Li. Carbon nanofiber-based composite for the construction of mediator-free biosensors. Biosensors and Bioelectronics. 2008, 23, 1236-1243. 

Xianbo Lu, Guifu Zou, Jinghong Li. Hemoglobin entrapped within a layered spongy Co3O4 based nanocomposite featuring direct electron transfer and peroxidase activity. Journal of Materials Chemistry. 2007, 17, 1427-1432. 

Xianbo Lu, Zhenhai Wen, Jinghong Li. Hydroxyl-containing antimony oxide bromide nanorods combined with chitosan for biosensors. Biomaterials. 2006, 27, 5740-5747. 

Xianbo Lu, Jianqiang Hu, Xin Yao, Zhouping Wang, Jinghong Li. Composite system based on Chitosan and Room Temperature Ionic Liquid: Direct electrochemistry and electrocatalysis of Hemoglobin. Biomacromolecules. 2006, 7, 975-980. 

Xianbo Lu, Qian Zhang, Ling Zhang, Jinghong Li. Direct electron transfer of horseradish peroxidase and its biosensor based on chitosan and room temperature ionic liquid. Electrochem. Commun., 2006, 8(5), 874-878. 

 Xianbo Lu, Shouguo Wu, Li Wang, Zhenxi Su. Solid-state amperometric hydrogen sensor based on polymer electrolyte membrane fuel cell. Sensor Actuator B-Chem., 2005, 107(2), 812-817.

Jianhua Zhou, Xianbo Lu, Jianqiang Hu, Jinghong Li. Reversible immobilization and direct electron transfer of Cytochrome c on pH sensitive polymer interface. Chem-Eur. J., 2007, 13(10), 2847-2853. 

Zhang, Haijun,Sufang,Yu, Ying,Ni, Yuwen,Lu, Xianbo,Tian, Yuzeng,Chen, Jiping. Retention of Nonionic Organic Compounds on Thermally Treated Soils. Environmental Science & Technology, 2010, 44, 3677-3682. 

Zhou, J.H., Liu, J., Wang, G., Lu, X.B., Wen, Z.H., and Li, J.H., Poly(N-isopropylacrylamide) interfaces with dissimilar thermo-responsive behavior for controlling ion permeation and immobilization. Advanced Functional Materials, 2007. 17(16), 3377-3382.

Zhou, J.H., Wang, G., Hu, J.Q., Lu, X.B.,  Li, J.H., Temperature, ionic strength and pH induced electrochemical switching of smart polymer interfaces. Chemical Communications, 2006(46), 4820-4822. 

Qing Liu, Xianbo Lu, Jun Li, Xin Yao, Jinghong Li. Direct electrochemistry of glucose oxidase and electrochemical biosensing of glucose on quantum dots/carbon nanotubes electrodes. Biosens. Bioelectron., 2007, 22(12), 3203-3209.

发表著作
(1) Molecular imprinted polymer-based biosensors for the detection of pharmaceutical contaminants in the environment, Tools, Techniques and Protocols for Monitoring Environmental Contaminants, Elsevier Inc, 2019-06, 第 4 作者
代表性成果 (2012年国家批准)
国家一级标准物质GBW10069 贻贝中有机氯农药和多氯联苯标准物质。
标准物质定级证书:证字第1247。