Fungal functional Genomics and Fungal biotechnology for industrial protein and biobased chemicals production.

2005-2009 Postdoc,  University of California at Berkeley

2009.12-  Professor, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences

1. Xue Pei, Junqi Zhao, Pengli Cai, Wenliang Sun, Jie Ren, Qiaqing Wu, Shihong Zhang, Chaoguang Tian*. Heterologous expression of a GH3 β-glucosidase from Neurospora crassa in Pichia pastoris with high purity and its application in the hydrolysis of soybean isoflavone glycosides. Protein Expression and Purification, 2016, vol 116, 75-84

2. Xue Pei, Feiyu Fan, Liangcai Lin, Yong Chen, Wenliang Sun, Shihong Zhang and Chaoguang Tian*. Involvement of the adaptor protein 3 complex in lignocellulase secretion in Neurospora crassa revealed by comparative genomic screening. Biotechnology for Biofuels (2015) 8:124

3. Feiyu Fan，Guoli Ma，Jingen Li，Qian liu，J.Philipp Benz，Chaoguang Tian* and Yanhe Ma：Genome-wide analysis of the endoplasmic reticulum stress response during lignocellulase production in Neurospora crassa. Biotechnology for Biofuels 2015 ,8:66.

4. Jingen Li, Jing Xu, Pengli Cai, Bang Wang, Yanhe Ma, J Philipp Benz and Chaoguang Tian*. The functional analysis of two related L-arabinose transporters from filamentous fungi reveals promising characteristics for improved pentose utilization in yeast . Applied and Environmental Microbiology, 2015, vol 81, 12:4062-4070.

5. Bang Wang, Pengli Cai, Wenliang Sun, Jingen Li, Chaoguang Tian*, Yanhe Ma. A transcriptomic    analysis of Neurospora crassa using five major crop residues and the novel role of the sporulation regulator rca-1 in lignocellulase production. Biotechnology for Biofuels. 2015, 8:21.

     6.  Junqi Zhao, Chao Guo, Chaoguang Tian* and Yanhe Ma. Heterologous Expression and   

Characterization of a GH3β-Glucosidase from Thermophilic Fungi Myceliophthora thermophila in Pichia pastoris. Appl Biochem Biotechnol. DOI 10.1007/s12010-015-1759-z

7. Qian Liu, Jingen Li, Shenghua Ying, Juanjuan Wang, Wenliang Sun, Chaoguang Tian and Mingguo Feng. Unveiling equal importance of two 14-3-3 proteins for morphogenesis, conidiation, stress tolerance and virulence of an insect pathogen. Environmental Microbiology. 2015. 

8. Pengli Cai, Bang Wang, Jingxiao Ji, Yongsheng Jiang, Li Wan, Chaoguang Tian,* and Yanhe Ma.The Putative Cellodextrin Transporter-like Protein CLP1 Is Involved in Cellulase Induction in Neurospora crassa. Journal of Biological Chemistry. 2015 290:788-796.

9. Jingen Li, Liangcai Lin, Huiyan Li, Chaoguang Tian＊ and Yanhe Ma. Transcriptional comparison of the filamentous fungus Neurospora crassa growing on three major monosaccharides D-glucose, D-xylose and L-arabinose. Biotechnology for Biofuels. 2014. 7:31.

10. Pengli Cai, Ruimeng Gu, Bang Wang, Jingen Li, Li Wan, Chaoguang Tian,* and Yanhe Ma. Evidence of a critical role for cellodextrin transporter 2 (CDT-2) in both cellulose and hemicellulose degradation and utilization in Neurospora crassa. Plos One. 2014. 9(2): e89330.

10. Bang Wang, Lina Lu, Hexin Lv, Huifeng Jiang, Ge Qu, Chaoguang Tian* and Yanhe Ma. The transcriptome landscape of Prochlorococcus MED4 and the factors for stabilizing the core genome. BMC Microbiology 2014, 14:11

11. Hexin Lv, Ge Qu, Xizhen Qi, Lina Lu, Chaoguang Tian* and Yanhe Ma. Transcriptome Analysis of Chlamydomonas reinhardtii during the Process of Lipid Accumulation. Genomics. 2013 doi: 10.1016/j.ygeno.2013.01.004.

12. Samuel T. Coradetti, James P. Craig, Yi Xiong, Teresa Shock, Chaoguang Tian, and N. Louise Glass.  Conserved and essential transcription factors for cellulase gene expression in ascomycete fungi. PNAS 2012 doi/10.1073

13. Monika Schmoll, Chaoguang Tian, Jianping Sun, Doris Tisch, N. Louise Glass. Unravelling the molecular basis for light modulated cellulase gene expression-the rôle of photoreceptors in Neurospora crassa. BMC Genomics 2012, 13:127

14. Jianping Sun, Chaoguang Tian, Spencer Diamond,  Louise Glass. Deciphering transcriptional regulatory mechanisms associated with hemicellulose degradation in Neurospora crassa.  Eukaryotic Cell 2012/doi: 10.1128/

15. Chaoguang Tian, Jingyi Li, N. Louise Glass. Exploring the bZIP transcription factor regulatory network in Neurospora crassa.  Microbiology  2011. doi:10.1099

16. Jonathan M. Galazka, Chaoguang Tian, William T. Beeson, Bruno Martinez, N. Louise Glass and Jamie H. D. Cate. Cellodextrin Transport in Yeast for Improved Biofuel Production.  Science. 2010. 330:84-86

17. Chaoguang Tian, William Beeson, Anthony Iavarone, Jianping Sun, Michael Marletta, Jamie Cate and Louise Glass. Systems analysis of plant cell wall degradation by the model filamentous fungus Neurospora crassa. PNAS 2009 vol. 106 no. 52 22157-22162 

18. Elizabeth Hutchison; Sarah Brown; Chaoguang Tian; N Louise Glass. Transcriptional profiling and functional analysis of heterokaryon incompatibility in Neurospora crassa reveals that reactive oxygen species, but not metacaspases, are associated with programmed cell death. Microbiology  2009;155(9):3957-70.

19. Arnaldo Videira; Takao Kasuga; Chaoguang Tian; Catarina Lemos; Ana Castro; N Louise Glass. Transcriptional analysis of the response of Neurospora crassa to phytosphingosine reveals links to mitochondrial function. Microbiology 2009;155 (9):3134-41.

20. Chaoguang Tian, Takao Kasuga, Matthew S.Sachs, N.Louise Glass*. Transcriptional profiling of cross pathway control in Neurospora crassa:  Comparative analysis of the Gcn4p and CPC1 regulons   Eukaryotic cell  2007 6: 1018-1029.

21. Jay Dunlap et. al., Enabling a community to dissect an organism: overview of the  Neurospora functional genomics project. Adv Genet. 2007 ; 57 :49-96

22. Takao Kasuga, Jeffrey P. Townsend, Chaoguang Tian, Luz B. Gilbert, Gertrud Mannhaupt, John W. Taylor and N. Louise Glass^*   Long-oligomer microarray profiling in Neurospora crassa reveals the transcriptional program underlying biochemical and physiological events of conidial germination. Nucleic Acids Research 2005 33(20):6469-6485

23. Xiong, Y., Liu, T., Tian, C., Sun, S., Li, J., Chen, M. (2005) Transcription factors in rice: a genome-wide comparative analysis between monocots and eudicots. Plant Molecular Biology. 59(1):191-203

24. Tian, C., Xiong, Y., Liu, T., Deng, W., Sun, S., Li, J., Chen, M. (2005) Evidence for An Ancient Whole Genome Duplication Event in Rice and Other Cereals. Acta Genetica Sinica.  32:519-527

   25. Tian, C., Wan, P., Sun, S., Li, J., and Chen, M. (2004) Genome-Wide Analysis of the GRAS Gene Family in Rice and Arabidopsis.

    Plant Molecular Biology.  54(4): 519-532

   26. Yu, J. et al. (2002) A draft sequence of rice genome (Oryza sativa L. ssp. indica)

   Science 296: 79-92