电子邮件： tian_cg@tib.cas.cn
通信地址： 天津空港经济区西七道32号
邮政编码： 300308
研究领域
真菌合成生物学研究组主要以丝状真菌为体系，以合成生物学理念为指导，利用生物设计和基因组编辑技术构建通用性丝状真菌底盘细胞，并结合各类组学、分子遗传学和代谢工程技术构建以生物质为原料，生产工业蛋白质和大宗化学品的高效细胞工厂。
招生信息
按计划招收硕士和博士研究生(具体见每年研究所招生计划); 包括国际留学生(入学前, 需要申请到TWAS或其他相应奖学金).
招生专业
招生方向
教育背景
工作经历
2005-2009 美国加州大学伯克利分校 博士后
2009.12-至今 中国科学院天津工业生物所 研究员
教授课程
专利与奖励
专利成果
出版信息
1. Liu Q, Li J, Gao R, Li J, Ma G, Tian C*. CLR-4, a novel conserved transcription factor for cellulase gene expression in ascomycete fungi. Mol Microbiol, 2019, 111: 2, 373-394
2. Gu S, Li J, Chen B, Sun T, Liu Q, Xiao D, Tian C*. Metabolic engineering of the thermophilic lamentous fungus Myceliophthora thermophila to produce fumaric acid. Biotechnol Biofuels, 2018, 11: 323
3. Lin L, Sun Z, Li J, Chen Y, Liu Q, Sun W, Tian C*. Disruption of gul-1 decreased the culture viscosity and improved protein secretion in the filamentous fungus Neurospora crassa. Microb Cell Fact, 2018, 17 (1): 96
4. Xu G, Li J, Liu Q, Sun W, Jiang M, Tian C*. Transcriptional analysis of Myceliophthora thermophila on soluble starch and role of regulator AmyR on polysaccharide degradation. Bioresour Technol, 2018, 265: 558-562
5. Wang B, Li J, Gao J, Cai P, Han X, Tian C*. Identification and Characterization of the Glucose Dual-Affinity Transport System in Neurospora crassa: Pleiotropic Roles in Nutrient Transport, Signaling, and Carbon Catabolite Repression. Biotechnol Biofuels, 2017, 10: 17
6. Liu Q, Gao R, Li J, Lin L, Zhao J, Sun W, Tian C*. Development of a genome-editing CRISPR/Cas9 system in thermophilic fungal Myceliophthora species and its application to hyper-cellulase production strain engineering. Biotechnol Biofuels, 2017, 10: 1
7. Fan F, Ma G, Li J, Liu Q, Benz JP, Tian C*, Ma Y. Genome-wide analysis of the endoplasmic reticulum stress response during lignocellulase production in Neurospora crassa. Biotechnol Biofuels. 2015, 8: 66
8. Li J, Xu J, Cai P, Wang B, Ma Y, Benz JP*, Tian C*. The functional analysis of two related L-arabinose transporters from filamentous fungi reveals promising characteristics for improved pentose utilization in yeast. Appl Environ Microbiol, 2015, 81 (12): 4062-4070
9. Wang B, Cai P, Sun W, Li J, Tian C*, Ma Y. A transcriptomic analysis of Neurospora crassa using five major crop residues and the novel role of the sporulation regulator rca-1 in lignocellulase production. Biotechnol Biofuels, 2015, 8: 21
10. Xu J, Li J, Lin L, Liu Q, Sun W, Huang B, Tian C*. Development of genetic tools for Myceliophthora thermophila. BMC Biotechnol, 2015, 15: 35
11. Pei X, Fan F, Lin L, Chen Y, Sun W, Zhang S*, Tian C*. Involvement of the adaptor protein 3 complex in lignocellulase secretion in Neurospora crassa revealed by comparative genomic screening. Biotechnol Biofuels, 2015, 8: 124
12. Cai P, Wang B, Ji J, Jiang Y, Wan L, Tian C*, Ma Y. The Putative Cellodextrin Transporter-like Protein CLP1 Is Involved in Cellulase Induction in Neurospora crassa. J Biol Chem, 2015, 290: 788-796