General
   

Research Areas

Microalgal Biology and Biotechnology

Education

2006       Ph.D.  Hydrobiology, Institute of Hydrobiology,Chinese Academy of Sciences, Wuhan, China.

            2001         B.S.  Biology, Wuhan University, Wuhan, China.


Experience

2014-Now            Professor, Institute of Hydrobiology, Chinese Academy of Sciences

2010-2014        Assistant Research Professor, Arizona State University.

2006-2010        Postdoctoral Research Associate, Arizona State University.

2001-2006        Research Associate, Institute of Hydrobiology, Chinese Academy of Sciences


Publications

  Zhen Zhang, Baobei Wang, Qiang Hu, Milton Sommerfeld, Yuanguang Li and Danxiang Han (2016). A new paradigm for producing astaxanthin from the unicellular green alga Haematococcus pluvialis. Biotechnology & Bioengineering, 2016, 9999

 Jin Liu, Danxiang Han, Kangsup Yoon, Qiang Hu, Yantao Li (2016) Characterization of type 2 diacylglycerol acyltransferase in Chlamydomonas reinhardtii reveals their distinct substrate specificities and function in triacylglycerol biosynthesis. Plant Journal 86:3-19

Jing Jia, Danxiang Han*, Henri G. Gerken, Yantao Li, Milton Sommerfeld, Qiang Hu, Jian Xu*. Molecular mecahnisms for  photosynthetic carbon partitioning into storage neutral lipids in Nannochloropsis oceanica under nitrogen-depletion conditions. Algal Research, 2015, 66-77 (Co-Corresponding author)

Guanqun Chen, Baobei Wang, Danxiang Han, Milton Sommerfeld, Yinghua Lu, Feng Chen and Qiang Hu (2015) Molecular mechanisms of the coordination between astaxanthin and fatty acid biosynthesis in Haematococcus pluvialis (Chlorophyceae). The Plant Journal  81(1):95-107 (Co-first author)

Baobei Wang, Zhen Zhang, Qiang Hu, Milton Sommerfeld, Yinghua Lu and Danxiang Han (2014) Cellular capacities for high-light acclimation and changing lipid profiles across life cycle stages of the green alga Haematococcus pluvialis. PLoS One 9(9): e106679

YunhoGwak, Yong-sic Hwang, Baobei Wang, Minju Kim, JooyeonJeong, Choul-Gyun Lee, Qiang Hu, Danxiang Han* & EonSeon Jin* (2014) Comparative analyses of lipidomes and transcriptomes reveals a concerted action of multiple defensive systems against photooxidative stress in Haematococcus pluvialis. Journal of Experimental Botany65: 4317-4334  (Co-Corresponding Author)

Li, J., Han, D.,Wang D., Ning, K., Jia, J., et al (2013) Choreography of transcriptomes and lipidomes of Nannochloropsis reveals the mechanisms of oleaginousness in microalgae. Plant Cell26: 1645-1665 (Co-First Author)

Wang, D., Ning, K., Li, J., Han, D., Wang H., et al (2014) Nannochloropsis phylogenome revealed evolution ofmicroalgal oleaginous traits. Plos Genetics 10: e1004094

Han, D., Li, Y. & Hu, Q. (2013) Astaxanthin in microalgae: Biosynthesis pathways, regulation and biotechnological applications. Algae 28: 131-147

Yoon, K.S., Han, D., Li, Y. Sommerfeld, M. & Hu Q. (2012) Phospholipid:diacylglycerol acyltransferase is a multifunctional enzyme involved in membrane lipid turnover and degradation while synthesizing triacylglycerol in the unicellular green microalga Chlamydomonas reinhardtii. Plant Cell 24: 3708-24 (Co-First Author)

Wang, J., Han, D., Sommerfeld, M. & Hu, Q. (2012) Effect of initial biomass density on growth and astaxanthin production of Haematococcus pluvialis in an outdoor photobioreactor. Journal of Applied Phycology DOI: 10.1007/S10811-012-9859-4

Han, D., Wang, J., Sommerfeld, M. & Hu, Q. (2012) Susceptibility and protective mechanisms of motile and non-motile cells of Haematococcus pluvialis (Chlorophyceae) to photooxidative stress. Journal of Phycology 48:693-705


Research Interests

Use multiple techniques including molecular and cellular biology, plant physiological and biochemical tools to address fundamental and applied biological questions in algae related to algae-based biofuels and chemicals. The current research interests are identification and characterization of the genes and their regulation in lipid synthesis, and understanding of the biogenesis of lipid bodies, and genetic engineering of microalgae for biofuels and high-value products


Students

已指导学生

曹黎  硕士研究生  071004-水生生物学  

李中泽  博士研究生  071007-遗传学  

郭晓烨  硕士研究生  071004-水生生物学  

顾小松  博士研究生  071004-水生生物学  

祝棉棉  硕士研究生  071004-水生生物学  

现指导学生

严海龙  博士研究生  071004-水生生物学  

肖玲  硕士研究生  071004-水生生物学  

邹松  博士研究生  071004-水生生物学  

冯晓云  硕士研究生  086000-生物与医药  

徐全  博士研究生  071004-水生生物学  

陈桥红  博士研究生  071004-水生生物学