General
Education
Ph.D., 2009, Bioinformatics, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei, China
M.S., 2007, Bioinformatics, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei, China
B.S., 2003, Aquaculture, Nanjing Agricultural University, Nanjing, Jiangsu, China
Experience
1. Assistant professor, 2013-2015
Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei, China
2. Associate professor, 2013-2015
Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei, China
Work Experience
1. Assistant professor, 2013-2015
Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei, China
2. Associate professor, 2013-2015
Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei, China
3. PostDoc, 2014,-2015
University of Michigan, Ann Arbor, USA
Publications
（1） Single-cell transcriptome sequencing of rumen ciliates provides insight into their molecular adaptations to the anaerobic and carbohydrate-rich rumen microenvironment, Molecular phylogenetics and evolution, 2020, 第 7 作者
（2） Sexual cell cycle initiation is regulated by CDK19 and CYC9 in Tetrahymena thermophila, Journal of Cell Science, 2020, 第 5 作者
（3） Proteomic identification and expression of oral apparatus constituents in cell regeneration of giant ciliate Stentor coeruleus (strain WHEL), Gene, 2020, 第 5 作者
（4） Tetrahymena Comparative Genomics Database (TCGD): a community resource for Tetrahymena, Database, 2019, 第 8 作者
（5） Insights into the origin and evolution of Peritrichia (Oligohymenophorea, Ciliophora) based on analyses of morphology and phylogenomics, Molecular phylogenetics and evolution, 2019, 第 3 作者
（6） RNAi-dependent Polycomb repression controls transposable elements in Tetrahymena, Genes & development, 2019, 第 2 作者
（7） Hidden genomic evolution in a morphospecies—The landscape of rapidly evolving genes in Tetrahymena, PLoS biology, 2019, 第 1 作者
（8） Exploration of Genetic Variations through Single‐cell Whole‐genome Sequencing in the Model Ciliate Tetrahymena thermophila, Journal of Eukaryotic Microbiology, 2019, 第 3 作者
（9） 进展中的原生动物学研究:热点领域与新格局, Progress of protozoological studies in China: Hot spots and new patterns, 中国科学:生命科学, 2019, 第 1 作者
（10） xploration of Genetic Variations through Single‐cell Whole‐genome Sequencing in the Model Ciliate Tetrahymena thermophila, Journal of Eukaryotic Microbiology, 2019, 第 3 作者
（11） EOGD: the Euplotes octocarinatus genome database, BMC Genomics, 2018, 第 4 作者
（12） A DP-like transcription factor protein interacts with E2fl1 to regulate meiosis in Tetrahymena thermophila, Cell cycle, 2018, 第 5 作者
（13） Pseudocohnilembus persalinus genome database-the first genome database of facultative scuticociliatosis pathogens, BMC genomics, 2018, 第 5 作者
（14） A germline-limited piggyBac transposase gene is required for precise excision in Tetrahymena genome rearrangement, Nucleic Acids Research, 2017, 第 4 作者
（15） Dissecting relative contributions of cis-and trans-determinants to nucleosome distribution by comparing Tetrahymena macronuclear and micronuclear chromatin, Nucleic Acids Research, 2016, 第 1 作者
（16） Epidermal growth factor-induced stimulation of proliferation and gene expression changes in the hypotrichous ciliate, Stylonychia lemnae, Gene, 2016, 通讯作者
（17） 四膜虫功能基因组数据库增量更新 2016-生活史和减数分裂转录组及磷酸化蛋白组资源建设, 基因组学与应用生物学, 2016, 通讯作者
（18） Tracing the structural evolution of eukaryotic ATP binding cassette transporter superfamily, Scientific reports, 2015, 第 1 作者
（19） Genome of the facultative scuticociliatosis pathogen Pseudocohnilembus persalinus provides insight into its virulence through horizontal gene transfer, Scientific reports, 2015, 第 1 作者
（20） The genome of the myxosporean Thelohanellus kitauei shows adaptations to nutrient acquisition within its fish host, Genome biology and evolution, 2014, 第 2 作者
（21） Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation, Genes & development, 2013, 第 2 作者
（22） Tetrahymena functional genomics database (TetraFGD): an integrated resource for Tetrahymena functional genomics, Database, 2013, 第 1 作者
（23） Transcriptome analysis of the model protozoan, Tetrahymena thermophila, using deep RNA sequencing, PLoS One, 2012, 第 1 作者
（24） Tetrahymena Gene Expression Database (TGED): a resource of microarray data and co-expression analyses for Tetrahymena, Science China Life sciences, 2011, 第 1 作者
（25） Gene network landscape of the ciliate Tetrahymena thermophila, PloS one, 2011, 第 1 作者
（26） Genome-wide identification and evolution of ATP-binding cassette transporters in the ciliate Tetrahymena thermophila: A case of functional divergence in a multigene family, BMC evolutionary biology, 2010, 第 1 作者
（2） Sexual cell cycle initiation is regulated by CDK19 and CYC9 in Tetrahymena thermophila, Journal of Cell Science, 2020, 第 5 作者
（3） Proteomic identification and expression of oral apparatus constituents in cell regeneration of giant ciliate Stentor coeruleus (strain WHEL), Gene, 2020, 第 5 作者
（4） Tetrahymena Comparative Genomics Database (TCGD): a community resource for Tetrahymena, Database, 2019, 第 8 作者
（5） Insights into the origin and evolution of Peritrichia (Oligohymenophorea, Ciliophora) based on analyses of morphology and phylogenomics, Molecular phylogenetics and evolution, 2019, 第 3 作者
（6） RNAi-dependent Polycomb repression controls transposable elements in Tetrahymena, Genes & development, 2019, 第 2 作者
（7） Hidden genomic evolution in a morphospecies—The landscape of rapidly evolving genes in Tetrahymena, PLoS biology, 2019, 第 1 作者
（8） Exploration of Genetic Variations through Single‐cell Whole‐genome Sequencing in the Model Ciliate Tetrahymena thermophila, Journal of Eukaryotic Microbiology, 2019, 第 3 作者
（9） 进展中的原生动物学研究:热点领域与新格局, Progress of protozoological studies in China: Hot spots and new patterns, 中国科学:生命科学, 2019, 第 1 作者
（10） xploration of Genetic Variations through Single‐cell Whole‐genome Sequencing in the Model Ciliate Tetrahymena thermophila, Journal of Eukaryotic Microbiology, 2019, 第 3 作者
（11） EOGD: the Euplotes octocarinatus genome database, BMC Genomics, 2018, 第 4 作者
（12） A DP-like transcription factor protein interacts with E2fl1 to regulate meiosis in Tetrahymena thermophila, Cell cycle, 2018, 第 5 作者
（13） Pseudocohnilembus persalinus genome database-the first genome database of facultative scuticociliatosis pathogens, BMC genomics, 2018, 第 5 作者
（14） A germline-limited piggyBac transposase gene is required for precise excision in Tetrahymena genome rearrangement, Nucleic Acids Research, 2017, 第 4 作者
（15） Dissecting relative contributions of cis-and trans-determinants to nucleosome distribution by comparing Tetrahymena macronuclear and micronuclear chromatin, Nucleic Acids Research, 2016, 第 1 作者
（16） Epidermal growth factor-induced stimulation of proliferation and gene expression changes in the hypotrichous ciliate, Stylonychia lemnae, Gene, 2016, 通讯作者
（17） 四膜虫功能基因组数据库增量更新 2016-生活史和减数分裂转录组及磷酸化蛋白组资源建设, 基因组学与应用生物学, 2016, 通讯作者
（18） Tracing the structural evolution of eukaryotic ATP binding cassette transporter superfamily, Scientific reports, 2015, 第 1 作者
（19） Genome of the facultative scuticociliatosis pathogen Pseudocohnilembus persalinus provides insight into its virulence through horizontal gene transfer, Scientific reports, 2015, 第 1 作者
（20） The genome of the myxosporean Thelohanellus kitauei shows adaptations to nutrient acquisition within its fish host, Genome biology and evolution, 2014, 第 2 作者
（21） Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation, Genes & development, 2013, 第 2 作者
（22） Tetrahymena functional genomics database (TetraFGD): an integrated resource for Tetrahymena functional genomics, Database, 2013, 第 1 作者
（23） Transcriptome analysis of the model protozoan, Tetrahymena thermophila, using deep RNA sequencing, PLoS One, 2012, 第 1 作者
（24） Tetrahymena Gene Expression Database (TGED): a resource of microarray data and co-expression analyses for Tetrahymena, Science China Life sciences, 2011, 第 1 作者
（25） Gene network landscape of the ciliate Tetrahymena thermophila, PloS one, 2011, 第 1 作者
（26） Genome-wide identification and evolution of ATP-binding cassette transporters in the ciliate Tetrahymena thermophila: A case of functional divergence in a multigene family, BMC evolutionary biology, 2010, 第 1 作者
Research Interests
Evolutionary genomics of protozoan
Students
现指导学生
李晨薇 硕士研究生 085238-生物工程