基本信息
俞飚  男  博导  中国科学院上海有机化学研究所
电子邮件: byu@sioc.ac.cn
通信地址: 上海市徐汇区零陵路345号1-306室
邮政编码: 200032

研究领域

具有重要生理活性的复杂寡糖、糖缀合物及其它天然产物的全合成、合成方法学和化学生物学。

招生信息

   
招生专业
070303-有机化学
招生方向
生命有机化学,糖化学

教育背景

1992-09--1995-07 中科院上海有机所 博士
1989-09--1992-07 中科院上海有机所 硕士
1985-09--1989-07 北京大学技术物理系 学士

工作经历

   
工作简历
1999-12--今 中科院上海有机所 研究员
1997-09--1999-11 中科院上海有机所 副研究员
1996-09--1997-08 中科院上海有机所 助理研究员
1995-09--1996-08 美国纽约大学化学系 博士后
社会兼职
2013-09--今 上海科技大学,教授
2010-09--今 上海高校E-化学生物学研究院,特聘研究员
2009-09--今 华东理工大学,特聘讲座教授
2004-09--今 中国科学技术大学,博师生导师

教授课程

天然产物合成的战略与战术
化学小分子全合成与化学生物学
现代有机合成与设计

专利与奖励

   
奖励信息
(1) 张树政糖科学杰出成就奖, 一等奖, 其他, 2019
(2) Fellow of the Royal Society of Chemistry, 其他, 2016
(3) “万人计划”第一批科技创新领军人才, , 部委级, 2014
(4) 中科院朱李月华优秀教师奖, 部委级, 2014
(5) 上海市首届青年科技杰出贡献奖, 一等奖, 省级, 2013
(6) 创新人才推进计划中青年科技创新领军人才, 部委级, 2013
(7) 上海市自然科学牡丹奖, 一等奖, 省级, 2012
(8) 国家自然科学奖, 二等奖, 国家级, 2010
(9) 上海市自然科学奖, 二等奖, 省级, 2006
专利成果
( 1 ) 一种原人参三醇类人参皂苷的制备方法, 发明, 2012, 第 1 作者, 专利号: 201210090482.5
( 2 ) 糖基聚醚、制备方法及用途, 发明, 2012, 第 1 作者, 专利号: CN101792524B
( 3 ) 虎眼万年青OSW-1 皂甙的无A、B 环的双环类似物,合成方法 和用途, 发明, 2010, 第 1 作者, 专利号: CN101089008B
( 4 ) 3-芳基-8-羟基色原酮-7-O-alpha-D-呋喃阿拉伯糖苷化 合物及其合成方法和用途, 发明, 2011, 第 1 作者, 专利号: 200810035318.8
( 5 ) 一种糖胺聚糖类化合物N,O-同时硫酸化的方法及其反应中间体, 发明, 2015, 第 1 作者, 专利号: ZL201510023345.3
( 6 ) 用于防治神经退行性疾病的新化合物及其应用, 发明, 2018, 第 2 作者, 专利号: 201810118796.9
( 7 ) 神经退行性疾病的治疗药物及其应用, 发明, 2018, 第 2 作者, 专利号: 201810616404.1
( 8 ) 一种视黄酸类化合物、其制备方法、中间体及应用, 发明, 2016, 第 2 作者, 专利号: 201610310944.8
( 9 ) 果同尼皂苷F及其衍生物的中间体, 制备方法和用途及果同尼皂苷F衍生物, 发明, 2014, 第 1 作者, 专利号: ZL201410045279.5

出版信息

   
发表论文
[1] Zhu, Dapeng, Geng, Mingyu, Yu, Biao. Total Synthesis of Starfish Cyclic Steroid Glycosides. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2022, 61(24): http://dx.doi.org/10.1002/anie.202203239.
[2] 俞飚. Tri(N‑carbazolyl)phosphine Gold(I) Complexes: Structural and Catalytic Activity Studies. Inorganic Chemistry[J]. 2022, [3] 俞飚. A Stereoselective Glycosylation Approach to the Construction of 1,2-trans-β-d-Glycosidic Linkages and Convergent Synthesis of Saponins. Chemistry - A European Journal[J]. 2022, [4] 俞飚. GeCl2·Dioxane−AgBF4 Catalyzed Activation of Glycosyl Fluorides for Glycosylation. Organic Letters[J]. 2022, [5] 俞飚. Chemical Synthesis of a Colanic Acid Hexasaccharide. Organic Letters[J]. 2022, [6] 俞飚. Total syntheses of wentilactones A and B, and related norditerpene dilactones. Chemical Communications[J]. 2022, [7] 俞飚. Total Synthesis and Stereochemistry Assignment of Nucleoside Antibiotic A-94964. Angewandte Chemie International Edition[J]. 2022, [8] Xu, Peng, Yu, Biao. Chemical synthesis of saponins: An update. ADVANCES IN CARBOHYDRATE CHEMISTRY AND BIOCHEMISTRY, VOL 79[J]. 2021, 79: 1-62, [9] Nicolardi, Simone, Joseph, A Abragam, Zhu, Qian, Shen, Zhengnan, PardoVargas, Alonso, Chiodo, Fabrizio, Molinaro, Antonio, Silipo, Alba, van der Burgt, Yuri E M, Yu, Biao, Seeberger, Peter H, Wuhrer, Manfred. Analysis of Synthetic Monodisperse Polysaccharides by Wide Mass Range Ultrahigh-Resolution MALDI Mass Spectrometry. ANALYTICAL CHEMISTRY[J]. 2021, 93(10): 4666-4675, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034773/.
[10] Elgehama, Ahmed, Sun, Lijun, Yu, Biao, Guo, Wenjie, Xu, Qiang. Selective targeting of the androgen receptor-DNA binding domain by the novel antiandrogen SBF-1 and inhibition of the growth of prostate cancer cells. INVESTIGATIONAL NEW DRUGS[J]. 2021, 39(2): 442-457, http://dx.doi.org/10.1007/s10637-020-01050-w.
[11] Wang, Ziqiang, Wei, Bingcheng, Mu, Tong, Xu, Peng, Yu, Biao. Facile Synthesis of Saikosaponins. MOLECULES[J]. 2021, 26(7): http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000638726800001.
[12] Yu, Biao, Wang, Shengyang. Solving the Structural Puzzles of Amipurimycin and Miharamycins Enabled by Stereodivergent Total Synthesis. CHEMICAL RECORD[J]. 2021, 21(11): 3015-3028, http://dx.doi.org/10.1002/tcr.202100057.
[13] Tang, Yu, Reddy, D Prabhakar, Yu, Biao. A dehydrative glycosylation protocol mediated by nonafluorobutanesulfonyl fluoride (NfF). TETRAHEDRON[J]. 2021, 78: http://dx.doi.org/10.1016/j.tet.2020.131800.
[14] Fu, Jiqiang, Xu, Peng, Yu, Biao. Total Synthesis of Nucleoside Antibiotics Amicetin, Plicacetin, and Cytosaminomycin A-D. CHINESE JOURNAL OF CHEMISTRY[J]. 2021, 39(10): 2679-2684, http://dx.doi.org/10.1002/cjoc.202100284.
[15] Mu, Tong, Xu, Peng, Yu, Biao. Facile Synthesis of Oleanane-type Pentacyclic Triterpenoids Bearing Hydroxy Groups on D/E Rings. ASIAN JOURNAL OF ORGANIC CHEMISTRY[J]. 2021, 10(7): 1752-1755, http://dx.doi.org/10.1002/ajoc.202100316.
[16] Wang, Yingjie, Yu, Biao. Total Syntheses of Aturanosides A and B. ORGANIC LETTERS[J]. 2021, 23(17): 6680-6684, http://dx.doi.org/10.1021/acs.orglett.1c02244.
[17] Liu, YanHua, Xia, YuNong, Gulzar, Tayyab, Wei, Bingcheng, Li, Haotian, Zhu, Dapeng, Hu, Zhifei, Xu, Peng, Yu, Biao. Facile access to C-glycosyl amino acids and peptides via Ni-catalyzed reductive hydroglycosylation of alkynes. NATURE COMMUNICATIONS[J]. 2021, 12(1): http://dx.doi.org/10.1038/s41467-021-25127-z.
[18] Cui, Zhaomeng, Liu, Yang, Wan, Wei, Xu, Yuyan, Hu, Yehui, Ding, Meng, Dou, Xin, Wang, Ruina, Li, Hailing, Meng, Yongmei, Li, Wei, Jiang, Wei, Li, Zengxia, Li, Yiming, Tan, Minjia, Ma, Dengke K, Ding, Yu, Liu, Jun O, Luo, Cheng, Yu, Biao, Tang, Qiqun, Dang, Yongjun. Ethacrynic acid targets GSTM1 to ameliorate obesity by promoting browning of white adipocytes. PROTEINCELL[J]. 2021, 12(6): 493-501, http://dx.doi.org/10.1007/s13238-020-00717-7.
[19] Chen, Jianpeng, Tang, Yu, Yu, Biao. A Mild Glycosylation Protocol with Glycosyl 1-Methylimidazole-2-carboxylates as Donors. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY[J]. 2021, 2021(30): 4333-4344, http://dx.doi.org/10.1002/ejoc.202100677.
[20] Xu Weichang, Liu Wei, Li Xiang, Xu Peng, Yu Biao. Synthesis of Oligosaccharides Relevant to the Substrates of Heparanase via Dehydrative Glycosylation. ACTA CHIMICA SINICA[J]. 2020, 78(8): 767-777, https://www.webofscience.com/wos/woscc/full-record/WOS:000567070900008.
[21] Prabhakar Reddy, D, Yu, Biao. Total Synthesis of Macrocyclic Dysoxylactam A. CHEMISTRY-AN ASIAN JOURNAL[J]. 2020, 15(16): 2467-2469, https://www.webofscience.com/wos/woscc/full-record/WOS:000548270100001.
[22] Zhao, Yachen, Wang, Shengyang, Yu, Biao. Dimerization of aldosuloses and aldonolactones into branched higher carbon sugars. CHEMICAL COMMUNICATIONS[J]. 2020, 56(13): 2020-2022, https://www.webofscience.com/wos/woscc/full-record/WOS:000514651200020.
[23] Zhou, Jintong, Zheng, Li, Hei, Zhoufei, Li, Wei, Wang, Jing, Yu, Biao, Fang, Pengfei. Atomic Resolution Analyses of Isocoumarin Derivatives for Inhibition of Lysyl-tRNA Synthetase. ACS CHEMICAL BIOLOGY[J]. 2020, 15(4): 1016-1025, https://www.webofscience.com/wos/woscc/full-record/WOS:000526890700027.
[24] 许伟长, 刘威, 李祥, 徐鹏, 俞飚. 脱水糖苷化方法合成肝素酶底物寡糖. 化学学报[J]. 2020, 78(8): 767-777, http://lib.cqvip.com/Qikan/Article/Detail?id=7103148088.
[25] 胡志飞, 徐鹏, 魏炳成, 俞飚. 苯丙素苷Acteoside,Isoacteoside和Ligupurpuroside J的全合成. 高等学校化学学报[J]. 2020, 41(8): 1708-1720, http://lib.cqvip.com/Qikan/Article/Detail?id=7102518317.
[26] Hu, Zhifei, Xu, Peng, Wei, Bingcheng, Yu, Biao. Total Synthesis of Phenylpropanoid Glycosides, Acteoside, Isoacteoside and Ligupurpuroside J. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE[J]. 2020, 41(8): 1708-1720, http://dx.doi.org/10.7503/cjcu20200266.
[27] Zhang, Liangzhong, Xu, Peng, Liu, Benzhang, Yu, Biao. Chemical Synthesis of Fucosylated Chondroitin Sulfate Oligosaccharides. JOURNAL OF ORGANIC CHEMISTRY[J]. 2020, 85(24): 15908-15919, https://www.webofscience.com/wos/woscc/full-record/WOS:000609003400014.
[28] 胡志飞, 徐鹏, 俞飚. 一条合成毛蕊花苷的新路线. 有机化学[J]. 2020, 40(10): 3439-3445, http://lib.cqvip.com/Qikan/Article/Detail?id=7103355114.
[29] Wang, Fei, Zhang, WenHe, Zhao, Juan, Kang, WenJia, Wang, Shengyang, Yu, Biao, Pan, HaiXue, Tang, GongLi. Characterization of Miharamycin Biosynthesis Reveals a Hybrid NRPS-PKS to Synthesize High-Carbon Sugar from a Complex Nucleoside. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2020, 142(13): 5996-6000, https://www.webofscience.com/wos/woscc/full-record/WOS:000526393700017.
[30] Zhou, Jintong, Huang, Zhenghui, Zheng, Li, Hei, Zhoufei, Wang, Zhiyong, Yu, Biao, Jiang, Lubin, Wang, Jing, Fang, Pengfei. Inhibition of Plasmodium falciparum Lysyl-tRNA synthetase via an anaplastic lymphoma kinase inhibitor. NUCLEIC ACIDS RESEARCH[J]. 2020, 48(20): 11566-11576, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672456/.
[31] Shao, Xiaofei, Wang, Xiaobo, Zhu, Kaidi, Dang, Yongjun, Yu, Biao. Synthesis of Sea Cucumber Saponins with Antitumor Activities. JOURNAL OF ORGANIC CHEMISTRY[J]. 2020, 85(19): 12080-12096, https://www.webofscience.com/wos/woscc/full-record/WOS:000577156600008.
[32] Sun, Lijun, Zhu, Di, Beverborg, Laura Olde Groote, Wang, Ruina, Dang, Yongjun, Ma, Mingming, Li, Wei, Yu, Biao. Synthesis and Antiproliferative Activities of OSW-1 Analogues Bearing 2 ''-O-p-Acylaminobenzoyl Residues. CHINESE JOURNAL OF CHEMISTRY[J]. 2020, 38(10): 1091-1097, https://www.webofscience.com/wos/woscc/full-record/WOS:000550535200001.
[33] Qian Zhu, Zhengnan Shen, Fabrizio Chiodo, Simone Nicolardi, Antonio Molinaro, Alba Silipo, Biao Yu. Chemical synthesis of glycans up to a 128-mer relevant to the O-antigen of Bacteroides vulgatus. NATURE COMMUNICATIONS[J]. 2020, 11(1): http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000607072900008.
[34] Li, Wei, Yu, Biao, Baker, DC. Temporary ether protecting groups at the anomeric center in complex carbohydrate synthesis. ADVANCES IN CARBOHYDRATE CHEMISTRY AND BIOCHEMISTRY, VOL 77null. 2020, 77: 1-69, https://www.webofscience.com/wos/woscc/full-record/WOS:000610756800002.
[35] Biao Yu. Coinage Metal (Bisfluorosulfonyl)imide Complexes: Preparation, Characterization, and Catalytic Applications Yu Tang. Asian Journal of Inorganic Chemistry. 2020, [36] Yin, Xuejian, Li, Wei, Yu, Biao. Synthesis of Pashinintide A, a Natural Cyclic Hexapeptide Supposedly Capable of Forming a Complex with Sucrose. ASIAN JOURNAL OF ORGANIC CHEMISTRY[J]. 2020, 9(1): 53-56, http://dx.doi.org/10.1002/ajoc.201900663.
[37] Mu, Tong, Wei, Bingcheng, Zhu, Dapeng, Yu, Biao. Site-selective C-H hydroxylation of pentacyclic triterpenoids directed by transient chiral pyridine-imino groups. NATURE COMMUNICATIONS[J]. 2020, 11(1): http://dx.doi.org/10.1038/s41467-020-18138-9.
[38] Hu, Zhifei, Xu, Peng, Yu, Biao. A New Approach to the Synthesis of Acteoside. CHINESE JOURNAL OF ORGANIC CHEMISTRY[J]. 2020, 40(10): 3439-3445, http://dx.doi.org/10.6023/cjoc202004052.
[39] Wang, Shengyang, Zhang, Qingju, Zhao, Yachen, Sun, Jiansong, Kang, Wenjia, Wang, Fei, Pan, Haixue, Tang, Gongli, Yu, Biao. The Miharamycins and Amipurimycin: their Structural Revision and the Total Synthesis of the Latter. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2019, 58(31): 10558-10562, http://dx.doi.org/10.1002/anie.201905723.
[40] Huang, Shichao, Cao, Xin, Zhou, Yue, Shi, Fuchun, Xin, Shunmei, He, Shufang, An, Yuclian, Gao, Longfei, Yang, Yongfeng, Yu, Biao, Pei, Gang. An analog derived from phenylpropanoids ameliorates Alzheimer's disease-like pathology and protects mitochondrial function. NEUROBIOLOGY OF AGING[J]. 2019, 80: 187-195, http://dx.doi.org/10.1016/j.neurobiolaging.2019.05.002.
[41] Hu, Zhifei, Tang, Yu, Yu, Biao. Glycosylation with 3,5-Dimethyl-4-(2 '-phenylethynylphenyl)phenyl (EPP) Glycosides via a Dearomative Activation Mechanism. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2019, 141(12): 4806-4810, https://www.webofscience.com/wos/woscc/full-record/WOS:000462950800005.
[42] Ehianeta, Teddy Stephen, Shen, Dacheng, Xu, Peng, Yu, Biao. Synthesis of spirostanol saponins via gold(I)-catalyzed glycosylation in the presence of Ga(OTf)(3), In(OTf)(3), or HOTf. CHINESE JOURNAL OF CHEMISTRY[J]. 2019, 37(8): 827-833, https://www.webofscience.com/wos/woscc/full-record/WOS:000475948400012.
[43] Sun, Lijun, Wang, Ruina, Wang, Xiaobo, Dang, Yongjun, Li, Wei, Yu, Biao. Synthesis and antiproliferative activities of OSW-1 analogues bearing 2-acylamino-xylose residues. ORGANIC CHEMISTRY FRONTIERS[J]. 2019, 6(14): 2385-2391, [44] Hu, Zhifei, Silipo, Alba, Li, Wei, Molinaro, Antonio, Yu, Biao. Synthesis of Forsythenethoside A, a Neuroprotective Macrocyclic Phenylethanoid Glycoside, and NMR Analysis of Conformers. JOURNAL OF ORGANIC CHEMISTRY[J]. 2019, 84(21): 13733-13743, [45] Shao Wenbo, An Quanlin, Cao Xin, Yu Biao. Efficient Synthesis of Representative Flavone-7-O-Glycosides. ACTA CHIMICA SINICA[J]. 2019, 77(10): 999-1007, [46] Yu, Biao. Tackling the challenge of glycosylation in the syntheses of complex natural glycosides. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETYnull. 2019, 258: https://www.webofscience.com/wos/woscc/full-record/WOS:000525055502112.
[47] 邵文博, 安泉林, 曹鑫, 俞飚. 灯盏花甲素、乙素等天然黄酮-7-O-糖苷的合成. 化学学报[J]. 2019, 77(10): 999-1007, http://lib.cqvip.com/Qikan/Article/Detail?id=7100438764.
[48] Zhu, Dapeng, Geng, Mingyu, Yang, Fuzhu, Yu, Biao. Strategies on the construction of 1,2-branched trans-beta-glycosidic linkages and their applications in the synthesis of saponins. JOURNAL OF CARBOHYDRATE CHEMISTRYnull. 2019, 38(7-8): 494-508, http://dx.doi.org/10.1080/07328303.2019.1642345.
[49] Kang, WenJia, Pan, HaiXue, Wang, Shengyang, Yu, Biao, Hua, Huiming, Tang, GongLi. Identification of the Amipurimycin Gene Cluster Yields Insight into the Biosynthesis of C9 Sugar Nucleoside Antibiotics. ORGANIC LETTERS[J]. 2019, 21(9): 3148-3152, [50] Tang, Yu, Yu, Biao. Coinage Metal (Bisfluorosulfonyl)imide Complexes: Preparation, Characterization, and Catalytic Applications. EUROPEAN JOURNAL OF INORGANIC CHEMISTRY. 2019, [51] Xiao, Guozhi, Shao, Xiaofei, Zhu, Dapeng, Yu, Biao. Chemical synthesis of marine saponins. NATURAL PRODUCT REPORTS[J]. 2019, 36(5): 769-787, [52] Shan, Yunlong, Gao, Yuan, Jin, Wei, Fan, Minmin, Wang, Ying, Gu, Yanhong, Shan, Chenxiao, Sun, Lijun, Li, Xin, Yu, Biao, Luo, Qiong, Xu, Qiang. Targeting HIBCH to reprogram valine metabolism for the treatment of colorectal cancer. CELL DEATH & DISEASE[J]. 2019, 10(8): http://dx.doi.org/10.1038/s41419-019-1832-6.
[53] Zhang, Xiaheng, Yu, Biao. Tackling the Challenge of the Total Synthesis of Periploside A. SYNLETT[J]. 2018, 29(13): 1683-1692, https://www.webofscience.com/wos/woscc/full-record/WOS:000440447700006.
[54] Liu, Chao, Ma, Yuyong, Pei, Chengfeng, Li, Wei, Yu, Biao. A Glycal Approach to the Synthesis of Pregnane Glycoside P57. CHINESE JOURNAL OF CHEMISTRY[J]. 2018, 36(11): 1007-1010, http://lib.cqvip.com/Qikan/Article/Detail?id=676786828.
[55] Yu, Biao. Gold(I)-Catalyzed Glycosylation with Glycosyl o-Alkynylbenzoates as Donors. ACCOUNTS OF CHEMICAL RESEARCHnull. 2018, 51(2): 507-516, https://www.webofscience.com/wos/woscc/full-record/WOS:000426014500032.
[56] Chao Liu, Yuyong Ma, Chengfeng Pei, Wei Li, Biao Yu. A Glycal Approach to the Synthesis of Pregnane Glycoside P57. 中国化学:英文版[J]. 2018, 36(11): 1007-1010, http://lib.cqvip.com/Qikan/Article/Detail?id=676786828.
[57] Shen Renzeng, Cao Xin, Yu Biao. Total Synthesis of Dammarane-Type Saponins Ginsenoside Re and Notoginsenoside R-1. ACTA CHIMICA SINICA[J]. 2018, 76(4): 278-285, https://www.webofscience.com/wos/woscc/full-record/WOS:000442405200004.
[58] Wang, Shengyang, Sun, Jiansong, Zhang, Qingju, Cao, Xin, Zhao, Yachen, Tang, Gongli, Yu, Biao. Amipurimycin: Total Synthesis of the Proposed Structures and Diastereoisomers. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2018, 57(11): 2884-2888, https://www.webofscience.com/wos/woscc/full-record/WOS:000426490700021.
[59] Shen, Renzeng, Laval, Stephane, Cao, Xin, Yu, Biao. Synthesis of Delta(20)-Ginsenosides Rh-4, (20E)-Rh-3, Rg(6), and Rk(1): A General Approach To Access Dehydrated Ginsenosides. JOURNAL OF ORGANIC CHEMISTRY[J]. 2018, 83(5): 2601-2610, https://www.webofscience.com/wos/woscc/full-record/WOS:000426803300010.
[60] Pei, Jian, Lu, XiaoBing, Yu, Biao, Yu, ZhiXiang. Organic Chemistry for the Future. ASIAN JOURNAL OF ORGANIC CHEMISTRYnull. 2018, 7(3): 489-489, https://www.webofscience.com/wos/woscc/full-record/WOS:000428351700001.
[61] Junwei Chen, Xin Cao, Quanlin An, Yao Zhang, Ke Li, Wenting Yao, Fuchun Shi, Yanfang Pan, Qiong Jia, Wenwen Zhou, Fang Yang, Fuxiang Wei, Ning Wang, Biao Yu. Inhibition of cancer stem cell like cells by a synthetic retinoid. NATURE COMMUNICATIONS[J]. 2018, 9(1): https://doaj.org/article/b6f1e3d96dae479b89a8288224c3c159.
[62] Shen Renzeng, Cao Xin, Yu Biao. Total Synthesis of Dammarane-Type Saponins Ginsenoside Re and Notoginsenoside R-1. ACTA CHIMICA SINICA[J]. 2018, 76(4): 278-285, http://dx.doi.org/10.6023/A17120544.
[63] Biao Yu. Total Synthesis of the Proposed Structures and Diastereoisomers.. Angew. Chem. Int. Ed.. 2018, [64] Li, Wei, Yu, Biao. Gold-catalyzed glycosylation in the synthesis of complex carbohydrate-containing natural products. CHEMICAL SOCIETY REVIEWSnull. 2018, 47(21): 7954-7984, https://www.webofscience.com/wos/woscc/full-record/WOS:000448662800007.
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[141] Zhang, Jian, Shi, Hefang, Ma, Yuyong, Yu, Biao. Expeditious synthesis of saponin P57, an appetite suppressant from Hoodia plants. CHEMICAL COMMUNICATIONS[J]. 2012, 48(69): 8679-8681, http://www.irgrid.ac.cn/handle/1471x/681937.
[142] Li, Wanshuai, Song, Ran, Fang, Xianying, Wang, Lu, Chen, Wei, Tang, Pingping, Yu, Biao, Sun, Yang, Xu, Qiang. SBF-1, a synthetic steroidal glycoside, inhibits melanoma growth and metastasis through blocking interaction between PDK1 and AKT3. BIOCHEMICAL PHARMACOLOGY[J]. 2012, 84(2): 172-181, http://dx.doi.org/10.1016/j.bcp.2012.04.006.
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[146] Li, Yali, Mo, Huaping, Lian, Gaoyan, Yu, Biao. Revisit of the phenol O-glycosylation with glycosyl imidates, BF3 center dot OEt2 is a better catalyst than TMSOTf. CARBOHYDRATE RESEARCH[J]. 2012, 363: 14-22, http://www.irgrid.ac.cn/handle/1471x/681948.
[147] Yang, Fei, Zhu, Yugen, Yu, Biao. A dramatic concentration effect on the stereoselectivity of N-glycosylation for the synthesis of 2 '-deoxy-beta-ribonucleosides. CHEMICAL COMMUNICATIONS[J]. 2012, 48(56): 7097-7099, http://dx.doi.org/10.1039/c2cc33155a.
[148] Yang, Weizhun, Sun, Jiansong, Yang, Zhongyi, Han, Wei, Zhang, WeiDong, Yu, Biao. Efficient synthesis of kaempferol 3,7-O-bisglycosides via successive glycosylation with glycosyl ortho-alkynylbenzoates and trifluoroacetimidates. TETRAHEDRON LETTERS[J]. 2012, 53(22): 2773-2776, http://dx.doi.org/10.1016/j.tetlet.2012.03.103.
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[150] Zhang, Jigang, Cao, Wenjie, Tian, Junmian, Yue, Rongcai, Li, Li, Guo, Baoyu, Shan, Lei, Yu, Biao, Zhang, Weidong. Evaluation of novel saponins from Psammosilene tunicoides and their analogs as immunomodulators. INTERNATIONAL IMMUNOPHARMACOLOGY[J]. 2012, 14(1): 21-26, http://dx.doi.org/10.1016/j.intimp.2012.06.006.
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[153] Yang, Fei, Wang, Qiaoling, Yu, Biao. ortho-Alkynylphenyl thioglycosides as a new type of glycosylation donors under the catalysis of Au(I) complexes. TETRAHEDRON LETTERS[J]. 2012, 53(39): 5231-5234, http://dx.doi.org/10.1016/j.tetlet.2012.07.059.
[154] Yu, Jun, Sun, Jiansong, Yu, Biao. Construction of Interglycosidic N-O Linkage via Direct Glycosylation of Sugar Oximes. ORGANIC LETTERS[J]. 2012, 14(15): 4022-4025, http://dx.doi.org/10.1021/ol301863j.
[155] Yang, Xiaoyu, Fu, Boqiao, Yu, Biao. Total Synthesis of Landomycin A, a Potent Antitumor Angucycline Antibiotic. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2011, 133(32): 12433-12435, http://dx.doi.org/10.1021/ja205339p.
[156] Cao, Wenjie, Yu, Biao. A Recyclable Polystyrene-Supported Gold(I) Catalyst. ADVANCED SYNTHESIS & CATALYSIS[J]. 2011, 353(11-12): 1903-1907, http://dx.doi.org/10.1002/adsc.201100133.
[157] Li, Yan, Sun, Jiansong, Yu, Biao. Efficient Synthesis of Lupane-Type Saponins via Gold(I)-Catalyzed Glycosylation with Glycosyl ortho-Alkynylbenzoates as Donors. ORGANIC LETTERS[J]. 2011, 13(20): 5508-5511, http://www.irgrid.ac.cn/handle/1471x/587867.
[158] Qingju Zhang, Jiansong Sun, Yugen Zhu, Fuyi Zhang, Biao Yu. An Efficient Approach to the Synthesis of Nucleosides: Gold(I)-Catalyzed N-Glycosylation of Pyrimidines and Purines with Glycosyl ortho-Alkynyl Benzoates†. ANGEW. CHEM.-INT. EDIT.[J]. 2011, 50(21): 4933-4936, http://www.irgrid.ac.cn/handle/1471x/587864.
[159] Li, Yali, Sun, Jiansong, Gong, Yanqing, Yu, Biao. Synthesis of Oligomeric 4-(Glycosyloxy)benzoate Macrocyclic Glycosides. JOURNALOFORGANICCHEMISTRY[J]. 2011, 76(10): 3654-3663, http://www.irgrid.ac.cn/handle/1471x/587860.
[160] Zhu, Yugen, Yu, Biao. Characterization of the Isochromen-4-yl-gold(I) Intermediate in the Gold(I)-Catalyzed Glycosidation of Glycosyl ortho-Alkynylbenzoates and Enhancement of the Catalytic Efficiency Thereof. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2011, 50(36): 8329-8332, http://dx.doi.org/10.1002/anie.201103409.
[161] Ma, Yuyong, Li, Zhongzhen, Shi, Hefang, Zhang, Jian, Yu, Biao. Assembly of Digitoxin by Gold(I)-Catalyzed Glycosidation of Glycosyl o-Alkynylbenzoates. JOURNAL OF ORGANIC CHEMISTRY[J]. 2011, 76(23): 9748-9756, http://www.irgrid.ac.cn/handle/1471x/587870.
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[163] Li, Yan, Yang, Weizhun, Ma, Yuyong, Sun, Jiansong, Shan, Lei, Zhang, WeiDong, Yu, Biao. Synthesis of Kaempferol 3-O-2 '',3 ''- and 2 '',4 ''-Di-O-(E)-p-coumaroyl-alpha-L-rhamnopyranosides. SYNLETT[J]. 2011, 915-918, http://www.irgrid.ac.cn/handle/1471x/587862.
[164] Ma, Yuyong, Lian, Gaoyan, Li, Yao, Yu, Biao. Identification of 3,6-di-O-acetyl-1,2,4-O-orthoacetyl-alpha-D-glucopyranose as a direct evidence for the 4-O-acyl group participation in glycosylation. CHEMICAL COMMUNICATIONS[J]. 2011, 47(26): 7515-7517, http://dx.doi.org/10.1039/c1cc11680k.
[165] Chan, Judy YuetWa, Koon, Johnny ChiMan, Liu, Xiaozhou, Detmar, Michael, Yu, Biao, Kong, SiuKai, Fung, KwokPui. Polyphyllin D, a steroidal saponin from Paris polyphylla, inhibits endothelial cell functions in vitro and angiogenesis in zebrafish embryos in vivo. JOURNAL OF ETHNOPHARMACOLOGY[J]. 2011, 137(1): 64-69, http://www.irgrid.ac.cn/handle/1471x/587868.
[166] Liao, Jinxi, Sun, Jiansong, Niu, Yiming, Yu, Biao. Synthesis of ginsenoside Rh2 and chikusetsusaponin-LT8 via gold(I)-catalyzed glycosylation with a glycosyl ortho-alkynylbenzoate as donor. TETRAHEDRON LETTERS[J]. 2011, 52(24): 3075-3078, http://dx.doi.org/10.1016/j.tetlet.2011.04.003.
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[169] Yang, You, Liu, Tian, Yang, Yongliang, Wu, Qingyue, Yang, Qing, Yu, Biao. Synthesis, Evaluation, and Mechanism of N,N,N-Trimethyl-D-glucosamine-(1 -> 4)-chitooligosaccharides as Selective Inhibitors of Glycosyl Hydrolase Family 20 beta-N-Acetyl-D-hexosaminidases. CHEMBIOCHEM[J]. 2011, 12(3): 457-467, http://www.irgrid.ac.cn/handle/1471x/587858.
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[181] Yang, Fei, Lian, Gaoyan, Yu, Biao. Synthesis of raphanuside, an unusual oxathiane-fused thioglucoside isolated from the seeds of Raphanus sativus L.. CARBOHYDRATE RESEARCH[J]. 2010, 345(2): 309-314, http://dx.doi.org/10.1016/j.carres.2009.11.020.
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[184] Chen, Chen, Yu, Biao. Efficient synthesis of Idraparinux, the anticoagulant pentasaccharide. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS[J]. 2009, 19(14): 3875-3879, http://dx.doi.org/10.1016/j.bmcl.2009.03.155.
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[188] Yang, You, Li, Yao, Yu, Biao. Total Synthesis and Structural Revision of TMG-chitotriomycin, a Specific Inhibitor of Insect and Fungal beta-N-Acetylglucosaminidases. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2009, 131(34): 12076-+, http://www.irgrid.ac.cn/handle/1471x/587838.
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[190] Tang, Pingping, Yu, Biao. Total Synthesis of Candicanoside A, a Rearranged Cholestane Disaccharide, and Its 4 ''-O-(p-Methoxybenzoate) Congener. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY[J]. 2009, 2009(2): 259-269, http://www.irgrid.ac.cn/handle/1471x/587843.
[191] Liao, Jinxi, Sun, Jiansong, Yu, Biao. Effective synthesis of nucleosides with glycosyl trifluoroacetimidates as donors. TETRAHEDRON LETTERS[J]. 2008, 49(34): 5036-5038, http://dx.doi.org/10.1016/j.tetlet.2008.06.042.
[192] 李瑶, 杨友, 俞飚. An efficient glycosylation protocol with glycosyl ortho-alkynylbenzoates as donors under the catalysis of Ph3PAuOTf. TETRAHEDRON LETT.[J]. 2008, 49(22): 3604-3608, http://ir.sioc.ac.cn/handle/331003/19081.
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[194] Wei, Guo, Yu, Biao. Isoflavone glycosides: Synthesis and evaluation as alpha-glucosidase inhibitors. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY[J]. 2008, 2008(18): 3156-3163, http://www.irgrid.ac.cn/handle/1471x/587828.
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[198] Yan CunYu, Yu Biao, Liu ShuYing, Cui Meng, Song FengRui, Liu ZhiQiang. Characterization of synthetic heparin-like compounds by negative electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY[J]. 2008, 36(7): 910-914, http://www.corc.org.cn/handle/1471x/2386993.
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[210] Yu, Biao, Zhang, Yichun, Tang, Pingping. Carbohydrate chemistry in the total synthesis of Saponins. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY[J]. 2007, 2007(31): 5145-5161, http://ir.sioc.ac.cn/handle/331003/19067.
[211] 李英霞, 张一纯, 郭甜甜, 管华诗, 郝妍, 俞飚. Synthesis of the cytotoxic gitogenin 3β-O-2-O-(α-L-rhamnopyranosyl) -β-D-galactopyranoside and its congeners.. SYNTHESIS[J]. 2006, 775-782, http://ir.sioc.ac.cn/handle/331003/19045.
[212] Li, Yuwen, Wei, Guo, Yu, Biao. Aryl C-glycosylation of phenols with glycosyl trifluoroacetimidates. CARBOHYDRATE RESEARCH[J]. 2006, 341(16): 2717-2722, http://dx.doi.org/10.1016/j.carres.2006.08.022.
[213] 李玉文, 魏国, 俞飚. Aryl C-glycosylation of phenols with glycosyl trifluoroacetimidates.. CARBOHYDR. RES.[J]. 2006, 341(16): 2717-2722, http://ir.sioc.ac.cn/handle/331003/19043.
[214] Li, Ming, Yu, Biao. Facile conversion of spirostan saponin into furostan saponin: Synthesis of methyl protodioscin and its 26-thio-analogue. ORGANIC LETTERS[J]. 2006, 8(13): 2679-2682, http://202.127.28.38/handle/331003/19035.
[215] Zhu, Cunsheng, Peng, Wenjie, Li, Yuwen, Han, Xiuwen, Yu, Biao. Synthesis of 3-O-(beta-D-xylopyranosyl-(1 -> 2)-beta-D-glucopyranosyl)-3 '-O-(beta-D-glucopyranosyl)tamarixetin, the putative structure of aescuflavoside A from the seeds of Aesculus chinensis. CARBOHYDRATE RESEARCH[J]. 2006, 341(8): 1047-1051, http://159.226.238.44/handle/321008/140159.
[216] 周映, 林峰, 陈建芳, 俞飚. Toward synthesis of the regular sequence of heparin: synthesis of two tetrasaccharide precursors acid; one pot. CARBOHYDR. RES.[J]. 2006, 341(10): 1619-1629, http://ir.sioc.ac.cn/handle/331003/19033.
[217] Peng WenJie, Han XiuWen, Yu Biao. Synthesis of C-aryl-flavonold derivatives via Suzuki-Miyaura coupling reaction. CHINESE JOURNAL OF CHEMISTRY[J]. 2006, 24(9): 1154-1162, http://159.226.238.44/handle/321008/98027.
[218] Zhou, Ying, Lin, Feng, Chen, Jianfang, Yu, Biao. Toward synthesis of the regular sequence of heparin: synthesis of two tetrasaccharide precursors. CARBOHYDRATE RESEARCH[J]. 2006, 341(10): 1619-1629, http://dx.doi.org/10.1016/j.carres.2006.02.020.
[219] 史炳峰, 汤平平, Xiaoyi Hu, Jun O. Liu, 俞飚. OSW saponins: facile synthesis toward a new type of structures with potent antitumo. J. ORG. CHEM.[J]. 2005, 70(25): 10354-10367, http://ir.sioc.ac.cn/handle/331003/19021.
[220] 张照军, 俞飚. Total synthesis of the antiallergic naphtho -α-pyrone tetraglucoside, cassiaside C^2 isolated from cassia seeds. J. ORG. CHEM.[J]. 2003, 68(16): 6309-6313, http://ir.sioc.ac.cn/handle/331003/18971.
[221] 汪红仪, 余伯阳, 俞飚, 惠永正. 激光共聚焦显微镜比较观察甾体皂苷Trilliuo、Lc253、Lc239对培养心肌细胞内Ca^2+i的作用. 中国天然药物[J]. 2003, 1(1): 41-43, http://lib.cqvip.com/Qikan/Article/Detail?id=7990445.
[222] 汪红仪, 余伯阳, 俞飚, 惠永正. Comparsion of intracellular Ca~2+ patterns affected by steriod saponin trilliuo, Lc253 and Lc239 in cultured cardiomyocytes revealed by confocal microscopy. CHIN. J. NAT. MED.[J]. 2003, 1(1): 41-43, http://ir.sioc.ac.cn/handle/331003/18969.
[223] 俞飚, 王平. Efficient synthesis of the hexasaccharide fragment of landomycin A: Using phenyl 2,3-0-Thionocarbonyl-1-thio-glycosides as 2-deoxy-β-glycoside. ORG. LETT.[J]. 2002, 4(11): 1919-1922, http://ir.sioc.ac.cn/handle/331003/18953.
[224] 韩秀文, 刘秀梅, 俞飚, 邢国文, 惠永正, 包信和. Total assignment of NMR spectral of the synthesized mono-and diacyl derivatives of diosgenyl saponins. MAGN. RESON. CHEM.[J]. 2002, 40(12): 789-792, http://ir.sioc.ac.cn/handle/331003/18945.
[225] 俞飚, 陶厚朝. Glycosyl trifluoroacetimidate. 2. Synthesis of dioscin and xiebai saponin I. J. ORG. CHEM.[J]. 2002, 67(25): 9099-9102, http://ir.sioc.ac.cn/handle/331003/18949.
[226] 朱向明, 曾文彬, 俞飚, 惠永正. 皂素皂苷脂肪链中甲基绝对构型的确定. 化学学报[J]. 2001, 59(10): 1653-1659, http://ir.sioc.ac.cn/handle/331003/18941.
[227] 唐于平, 俞飚, 胡杰, 吴弢, 惠永正. The chemical constituents from the bulbs of ornithogalum caudatum. J. CHIN. PHARMACEUT. SCI.[J]. 2001, 10(4): 169-172, http://ir.sioc.ac.cn/handle/331003/18943.
[228] 杨尊义, 俞飚. Stereoselective synthesis of 2-S-phenyl-2-deoxy-β-glycosides using phenyl 2,3-O-Thionocarbonyl-1-thioglycoside donors via 1,2-migration and concurrent glycosidation. ORG. LETT.[J]. 2001, 3(3): 377-379, http://ir.sioc.ac.cn/handle/331003/18921.
[229] 杨尊义, 俞飚. Stereoselective synthesis of 2-S-ethyl(phenyl)-2-thio-β-glucopyranosides via 1,2-migration and concurrent glycosidation of ehtyl(phenyl)2,3-orthoester-1-thio-α-mannopyranosides. CARBOHYDR. RES.[J]. 2001, 333(1): 105-114, http://ir.sioc.ac.cn/handle/331003/18925.
[230] 朱向明, 俞飚, 惠永正. 葡萄糖醛酸苷合成进展. 有机化学[J]. 2000, 20(2): 146-154, http://ir.sioc.ac.cn/handle/331003/18911.
[231] 马兴泉, 俞飚, 惠永正, 肖东, 丁健. Synthesis of glycosides bearing the disaccharide of OSW-1 or its 1→4 linked analogue and their antitumor activities.. CARBOHYDR. RES.[J]. 2000, 329(3): 495-505, http://ir.sioc.ac.cn/handle/331003/18899.
[232] 张剑波, 俞飚, 惠永正. 双糖链甾体皂甙的研究进展. 有机化学[J]. 2000, 20(5): 663-668, http://ir.sioc.ac.cn/handle/331003/18913.
[233] 杨尊义, 林文彬, 俞飚. Rearrangement of sugar 1,2-orthoester to glycosidec product: a mechanistic implication. CARBOHYDR. RES.[J]. 2000, 329(4): 879-884, http://ir.sioc.ac.cn/handle/331003/18915.
[234] 于海, 俞飚, 吴向阳, 惠永正, 韩秀文. Synthesis of a group of diosgenyl saponins with a combined use of glycosyl trichloroacetimidate and thioglycoside. J. CHEM. SOC.-PERKIN TRANS. 1[J]. 2000, 1445-1453, http://ir.sioc.ac.cn/handle/331003/18905.
[235] 于海, 韩秀文, 刘秀梅, 俞飚, 惠永正, 包信和. NMR Studies on synthesized diosgenyl saponins. MAGN. RESON. CHEM.[J]. 2000, 38(8): 704-706, http://ir.sioc.ac.cn/handle/331003/18907.
[236] 朱向明, 俞飚, 惠永正. Di-O-benzoyl-α-D-xylopyranoside and its X-ray structure.. CHIN. J. CHEM.[J]. 2000, 18(1): 72-75, http://ir.sioc.ac.cn/handle/331003/18909.
[237] 刘美正, 俞飚, 吴向阳, 惠永正, 冯国培. Synthesis of 25(R)-ruscogenin-1-yl-β-D-xylopyranosyl-(1→3)-β-Dglucopyranosyl-(1→2)-β-D-fucopyranoside.. CARBOHYDR. RES.[J]. 2000, 329(4): 745-754, http://ir.sioc.ac.cn/handle/331003/18917.
[238] 俞飚, 杨尊义. A novel and expeditious approach to the stereoselective synthesis of 2-S-ethyl(phenyl)-2-deoxy-β-glycosides, ready precursors to 2-Deoxy-β-glycosides.. TETRAHEDRON LETT.[J]. 2000, 41(16): 2961-2964, http://ir.sioc.ac.cn/handle/331003/18901.
[239] 韩秀文, 于海, X.M. Liu, X. Bao, 俞飚, 李川, 惠永正. Complete ^1H and ^13C NMR assignments of diosgenyl saponins. MAGN. RESON. CHEM.[J]. 1999, 37(2): 140-144, http://ir.sioc.ac.cn/handle/331003/18881.
[240] 卢寿福, 鸥阳琴琴, 郭忠武, 俞飚, 惠永正. Synthesis of propyl O-(α-L-rhamnopyranosyl)-(1→ 3)-2,4- di-O-(2s-methylbutyryl)-α-L-rhamnopyranosyl-(1→ 2)-(3-O- acetyl-β-D-glucopyranosyl)-(1→2)-β-D-fucopyranoside, the tetrasaccharide moiety of Tricolorin A. CHIN. J. CHEM.[J]. 1998, 16(1): 0078-0089, http://ir.sioc.ac.cn/handle/331003/18865.
[241] 刘美正, 俞飚, 惠永正. First total synthesis of 25(R)-ruscogenin-1-yl β -D- xylopyranosyl-(1→3)-β-Dglucopyranosyl-(1→)-β- Dfucopyranoside, an ophiopogonis saponin from the tuber of liriope muscari (Decne.). TETRAHEDRON LETT.[J]. 1998, 39: 0415-0418, http://ir.sioc.ac.cn/handle/331003/18875.
[242] 卢寿福, 欧阳琴琴, 郭忠武, 俞飚, 惠永正. An efficient one-step methyl esterificaiton of carboxylic acid and deacetylation of alcohol under BF3.OEt2-MeOH. CHIN. CHEM. LETT.[J]. 1997, 8(10): 0843-0844, http://ir.sioc.ac.cn/handle/331003/18855.
[243] 卢寿福, 欧阳琴琴, 郭忠武, 俞飚, 惠永正. First total synthesis of tricolorin A. ANGEW. CHEM.-INT. EDIT.[J]. 1997, 36(21): 2344-2346, http://ir.sioc.ac.cn/handle/331003/18853.
[244] 俞飚, 惠永正. Supramolecular assemblies from single-chainhydrocarbon fluorocarbon hydrid bolaamphiphiles. CHIN. J. CHEM.[J]. 1996, 14(2): 0171-0179, http://ir.sioc.ac.cn/handle/331003/18849.
[245] 俞飚. 双端头基碳氢碳氟杂化单链兼亲分子聚集体的研究. 1995, http://ir.sioc.ac.cn/handle/331003/6565.
[246] 俞飚, 惠永正. Stereospecific synthesis of α-D-fructofuranosides: synthesis of the oligo-fructan diastereoisomers. CHIN. CHEM. LETT.[J]. 1993, 4(4): 285-286, http://ir.sioc.ac.cn/handle/331003/18837.
[247] Shichao Huang, Xin Cao, Yue zhou, Fuchun Shi, Shunmei Xin, Shufang He, Yuqian An, Longfei Gao, Yongfeng Yang, Biao Yu, Gang Pei. An analogue derived from phenylpropanoids ameliorates Alzheimer’s disease-like pathology and protects mitochondrial function. NEUROBIOLOGY OF AGING. http://dx.doi.org/10.1016/j.neurobiolaging.2019.05.002.

科研活动

   
科研项目
( 1 ) 复杂核苷类抗生素ampurimycin及miharamycin的全合成研究, 参与, 国家级, 2014-01--2017-12
( 2 ) 糖基转移酶抑制剂衣霉素(Tunicamycin)的全合成和多样性合成研究, 主持, 国家级, 2014-01--2017-12
( 3 ) 复杂糖缀合物的合成及高效糖苷化方法的研究, 主持, 国家级, 2015-01--2019-12
( 4 ) 天然产物的化学生物学, 主持, 国家级, 2017-01--2022-12
( 5 ) 复杂糖缀物[6-deoxy-L-Altp]n和amipurimycin 1的鉴定,合成和动力学研究, 主持, 国家级, 2016-01--2018-12
( 6 ) 蛋白质糖基化的化学标记与功能调控, 参与, 国家级, 2018-05--2023-04
( 7 ) 针对蛋白质糖基化的特异化学探针, 主持, 国家级, 2018-05--2023-04
( 8 ) 聚糖和糖缀合物的程式化合成和多功能解析, 主持, 部委级, 2019-09--2024-09
( 9 ) 新型抗生素Amycolamicin的全合成和构效关系研究, 主持, 国家级, 2019-01--2022-12
( 10 ) 破译磷酸乙醇胺转移酶MCR-1(一种粘菌素抗性蛋白)的作用机制及开发过渡态抑制剂, 主持, 国家级, 2019-01--2022-12
( 11 ) 深海动植物药物先导化合物的规模化全合成与优化, 主持, 国家级, 2018-08--2021-12
( 12 ) 重要复杂天然产物的高效全合成, 主持, 部委级, 2018-06--2020-12
参与会议
(1) 大会主席,第24届国际杂环化学会议,2013-09,俞飚
(2) 大会主席,第三届亚洲糖化学会议,2011-10,俞飚

指导学生

已指导学生

王一兵  博士研究生  070303-有机化学  

陈友喜  博士研究生  070303-有机化学  

李瑶  博士研究生  070303-有机化学  

曹文杰  博士研究生  070303-有机化学  

许伟长  博士研究生  070303-有机化学  

杨飞  博士研究生  070303-有机化学  

杨晓瑜  博士研究生  070303-有机化学  

马玉勇  博士研究生  070303-有机化学  

徐鹏  博士研究生  070303-有机化学  

张夏衡  博士研究生  070303-有机化学  

朱玉根  博士研究生  070303-有机化学  

马君君  硕士研究生  085238-生物工程  

代元伟  博士研究生  070303-有机化学  

现指导学生

唐宇  博士研究生  070303-有机化学  

邵文博  博士研究生  070303-有机化学  

刘超  硕士研究生  070303-有机化学  

沈铮男  硕士研究生  070303-有机化学  

沈大成  硕士研究生  070303-有机化学  

朱大鹏  博士研究生  070303-有机化学  

陈小平  博士研究生  070303-有机化学  

郭政  硕士研究生  070303-有机化学  

尹雪健  硕士研究生  070303-有机化学  

张良忠  硕士研究生  070303-有机化学  

付纪强  硕士研究生  070303-有机化学  

王生阳  博士研究生  070303-有机化学  

张浩亮  博士研究生  070303-有机化学  

沈仁增  博士研究生  070303-有机化学  

曾长根  博士研究生  070303-有机化学