General
Biao Yu   Full Professor
Shanghai Institute of Organic Chemistry

Email: byu@mail.sioc.ac.cn
Telephone: 2154925131
Address: Room 1-306, 345 Lingling Road. 
Postcode: 200032

Research Areas

Total Synthesis, Synthetic Methodology, and Chemical Biology of biologically significant oligosaccharides, glycoconjugates, and other natural products, especially the glycosaminoglycans of mammal, antibiotics of microbe, glycosides of plants and marine species. And Chemistry of the Traditional Chinese Medicine.

Education

1992-1995: Ph.D. in Organic Chemistry;
1989-1992: M.S. in Organic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
1985-1989: B.S. in Nuclear Chemistry, Peking University

Experience

   
Work Experience
1999.12–present: Professor;
1997.9–2000.11: Associate Professor;
1996.9–1997.8: Assistant Professor, Shanghai Institute of Organic Chemistry,
Chinese Academy of Sciences
1995.9–1996.8: Postdoc, Dept. of Chemistry, New York University

Publications

   
Papers

(1) Total Synthesis of Linckosides A and B, the Representative Starfish Polyhydroxysteroid Glycosides with Neuritogenic Activities. Dapeng Zhu, Biao Yu, J. Am. Chem. Soc. 2015137, 15098-15101.

(2) Total synthesis of periploside A, a unique pregnane hexasaccharide with potent immunosuppressive effects. Xiaheng Zhang, Yu Zhou, Jianping Zuo, Biao Yu, Nat. Commun. 2015, 6, 5879.
(3) A Modular Approach to the Total Synthesis of Tunicamycins. Jiakun Li, Biao Yu, Angew. Chem. Int. Ed. 2015, 54, 6618-6621.
(4) Molecular matchmaking between the popular 'weight loss' herb Hoodia gordonii and GPR119, a potential drug target for metabolic disorder. S. Zhang, Y. Ma, J. Ma, B. Yu, X. Xie, Proc. Natl. Acad. Sci. USA 2014, 111, 14571-14576.
(5) Total synthesis of nucleoside antibiotic A201A. S. Nie, W. Li, B. Yu, J. Am. Chem. Soc. 2014, 136, 4157-4160.
(6) Mechanistic insights into the gold(I)-catalyzed activation of glycosyl ortho-alkynylbenzoates for glycosidation Y. Tang, J. Li, Y. Zhu, Y. Li, B. Yu, J. Am. Chem. Soc. 2013, 135, 18396-18405.
(7) Synthetic access toward the diverse ginsenosides. J. Yu, J. Sun, Y. Niu, R. Li, J. Liao, F. Zhang, B. Yu, Chem. Sci. 2013, 4, 3899-3905.
(8) Assembly of naturally occurring glycosides, evolved tactics and glycosylation methods. B. Yu, J. Sun, X. Yang, Acc. Chem. Res. 2012, 45, 1227-1236.
(9) An efficient approach to the synthesis of nucleosides, gold(I)-catalyzed N-glycosylation of pyrimidines and purines with glycosyl ortho-alkynylbenzoates. Q. Zhang, J. Sun, Y. Zhu, F. Zhang, B. Yu, Angew. Chem. Int. Ed. 2011, 50, 4933-4936.
(10) Total synthesis of landomycin A, a potent antitumor angucycline antibiotic. X. Yang, B. Fu, B. Yu, J. Am. Chem. Soc. 2011, 133, 12433-12435.

Conferences

Chairman, The 24th International Society of Heterocyclic Chemistry Congress (ISHC-24), 2013.
Chairman, The 3rd Asian Community of Glycoscience and Glycotechnology (ACGG), 2011.

Students

已指导学生

王一兵  博士研究生  070303-有机化学  

陈友喜  博士研究生  070303-有机化学  

李瑶  博士研究生  070303-有机化学  

曹文杰  博士研究生  070303-有机化学  

许伟长  博士研究生  070303-有机化学  

杨飞  博士研究生  070303-有机化学  

杨晓瑜  博士研究生  070303-有机化学  

马玉勇  博士研究生  070303-有机化学  

徐鹏  博士研究生  070303-有机化学  

张夏衡  博士研究生  070303-有机化学  

朱玉根  博士研究生  070303-有机化学  

马君君  硕士研究生  085238-生物工程  

代元伟  博士研究生  070303-有机化学  

唐宇  博士研究生  070303-有机化学  

邵文博  博士研究生  070303-有机化学  

朱大鹏  博士研究生  070303-有机化学  

沈大成  硕士研究生  070303-有机化学  

现指导学生

刘超  硕士研究生  070303-有机化学  

沈铮男  博士研究生  070303-有机化学  

陈小平  博士研究生  070303-有机化学  

郭政  硕士研究生  070303-有机化学  

尹雪健  硕士研究生  070303-有机化学  

张良忠  硕士研究生  070303-有机化学  

付纪强  硕士研究生  070303-有机化学  

王英杰  硕士研究生  070303-有机化学  

邵笑飞  硕士研究生  070303-有机化学  

王生阳  博士研究生  070303-有机化学  

张浩亮  博士研究生  070303-有机化学  

沈仁增  博士研究生  070303-有机化学  

曾长根  博士研究生  070303-有机化学