基本信息
陈祖昕  男    中国科学院深圳先进技术研究院
电子邮件: zx.chen3@siat.ac.cn
通信地址: 深圳南山区西丽大学城学苑大道1068号
邮政编码:

招生信息

   
招生专业
071006-神经生物学
招生方向
成瘾,戒烟药物研发,血糖调控,尼古丁 与 糖尿病

教育背景

2014-03--2019-01   美国纽约西奈山医学院   博士后
2010-05--2014-02   马克斯普朗克佛罗里达神经科学研究所   博士联合培养
2008-12--2010-05   马克斯普朗克生物物理化学研究所   博士联合培养
2007-09--2013-12   华中科技大学   博士学位
2003-09--2007-07   华中科技大学   学士

工作经历

   
工作简历
2019-01~现在, 中国科学院深圳先进技术研究院, 副研究员

专利与奖励

   
专利成果
[1] 陈祖昕, 刘欣安. 米非司酮干预和治疗尼古丁成瘾的用途. CN: CN114652730A, 2022-06-24.
[2] 刘子俊, 刘欣安, 王立平, 陈祖昕. 基于声表面波技术的便携式精准可视化雾化递送设备. CN: CN114470433A, 2022-05-13.
[3] 刘子俊, 刘欣安, 王立平, 陈祖昕. 基于声表面波技术的便携式精准可视化雾化递送设备. CN: CN114470433A, 2022-05-13.
[4] 刘子俊, 刘欣安, 王立平, 陈祖昕. 基于声表面波技术的便携式精准可视化雾化递送设备. CN: CN114470433A, 2022-05-13.
[5] 陈祖昕, 刘欣安, 莫之准. 一种评估尼古丁成瘾程度或评估待测药物对于尼古丁成瘾程度的影响的方法. CN: CN114432461A, 2022-05-06.
[6] 陈祖昕, 刘欣安, 莫之准. 一种评估尼古丁成瘾程度或评估待测药物对于尼古丁成瘾程度的影响的方法. CN: CN114432461A, 2022-05-06.
[7] 刘欣安, 陈祖昕, 王立平. 一种电子烟器具. CN: CN113491351A, 2021-10-12.
[8] 刘欣安, 王立平, 汤佳航, 徐智彬, 陈祖昕. 一种烟弹及电子烟. CN: CN113491350A, 2021-10-12.
[9] 陈祖昕, 刘欣安, 莫之准, 韩亚宁, 王立平. 一种雾化物奖赏性和成瘾性的评估设备和评估方法. CN: CN112730738A, 2021-04-30.
[10] 蒋蓝萍, 姚诗琪, 刘欣安, 陈祖昕, 王立平. 动物饮水选择实验装置. CN: CN211353481U, 2020-08-28.

出版信息

   
发表论文
[1] Ming Chu, Ruoxi Wang, Xiaoyuan Jing, Ding Li, Guofeng Fu, Jingjing Deng, Zhibin Xu, Jing Zhao, Zhang Liu, Qiming Fan, Lanjie Pei, Zhi Zeng, Chuan Liu, Zuxin Chen, Jin Lu, Xinan Liu. Conventional and multi-omics assessments of subacute inhalation toxicity due to propylene glycol and vegetable glycerin aerosol produced by electronic cigarettes. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY[J]. 2024, 271: 116002-, https://doaj.org/article/5fbed57729e54fb2bdbfc129bab6ffe8.
[2] Xinli Xu, Shuidiao Zheng, Jiayan Ren, Zixuan Li, 刘欣安, 陈祖昕. Hypothalamic CRF neurons facilitate brain reward function. Current Biology[J]. 2024, [3] Axiang Li, Weifen Li, Tahir Ali, Canyu Yang, Zizhen Liu, Ruyan Gao, Kaiwu He, Xinan Liu, Zuxin Chen, ZhiJian Yu, Tao Li, Shupeng Li. A novel dopamine D2 receptor-NR2B protein complex might contribute to morphine use disorders. EUROPEAN JOURNAL OF PHARMACOLOGY. 2023, 961: http://dx.doi.org/10.1016/j.ejphar.2023.176174.
[4] Zuxin Chen, Xinan Liu, Paul J Kenny. Central and peripheral actions of nicotine that influence blood glucose homeostasis and the development of diabetes. PHARMACOLOGICAL RESEARCH[J]. 2023, 194: 106860-, http://dx.doi.org/10.1016/j.phrs.2023.106860.
[5] Xiaoyuan Jing, Feng Hong, Yinfang Xie, Yutong Xie, Feng Shi, Ruoxi Wang, Liping Wang, Zuxin Chen, Xinan Liu. Dose-dependent action of cordycepin on the microbiome-gut-brain-adipose axis in mice exposed to stress. BIOMEDICINE & PHARMACOTHERAPY. 2023, 168: http://dx.doi.org/10.1016/j.biopha.2023.115796.
[6] Xianglian Jia, Shanping Chen, Xulin Li, Sijue Tao, Juan Lai, Haoran Liu, Kang Huang, Ye Tian, Pengfei Wei, Fan Yang, Zhonghua Lu, Zuxin Chen, Xinan Liu, Fuqiang Xu, Liping Wang. Divergent neurocircuitry dissociates two components of the stress response: glucose mobilization and anxiety-like behavior. CELL REPORTS. 2022, 41(6): http://dx.doi.org/10.1016/j.celrep.2022.111586.
[7] Jia, Shuhui, Guo, Xuantong, Chen, Zuxin, Li, Shupeng, Liu, Xinan. The roles of the circadian hormone melatonin in drug addiction. PHARMACOLOGICAL RESEARCHnull. 2022, 183: http://dx.doi.org/10.1016/j.phrs.2022.106371.
[8] Chu, Ming, Fu, Guofeng, Deng, Jingjing, Wang, Ruoxi, Fan, Qiming, Chen, Zuxin, Lu, Jin, Liu, XinAn. Evaluation of the inhalation toxicity of arecoline benzoate aerosol in rats. JOURNAL OF APPLIED TOXICOLOGY[J]. 2022, 42(8): 1396-1410, http://dx.doi.org/10.1002/jat.4303.
[9] Muhammad, Fahim, Fan, Bufang, Wang, Ruoxi, Ren, Jiayan, Jia, Shuhui, Wang, Liping, Chen, Zuxin, Liu, XinAn. The Molecular Gut-Brain Axis in Early Brain Development. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESnull. 2022, 23(23): http://dx.doi.org/10.3390/ijms232315389.
[10] Xu, Zhibin, Tian, Ye, Li, A Xiang, Tang, Jiahang, Jing, XiaoYuan, Deng, Chunshan, Mo, Zhizhun, Wang, Jiaxuan, Lai, Juan, Liu, Xuemei, Guo, Xuantong, Li, Tao, Li, Shupeng, Wang, Liping, Lu, Zhonghua, Chen, Zuxin, Liu, Xinan. Menthol Flavor in E-Cigarette Vapor Modulates Social Behavior Correlated With Central and Peripheral Changes of Immunometabolic Signalings. FRONTIERS IN MOLECULAR NEUROSCIENCE[J]. 2022, 15: http://dx.doi.org/10.3389/fnmol.2022.800406.
[11] Jia, Xianglian, Liu, Xinan, Shi, Yan, Yao, Shiqi, Zhong, Xin, Tian, Ye, Tian, Qing, Chen, Zuxin, Wang, Liping. Profiling of key brain nuclei involved in CNS control of stress and glucose homeostasis. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2020, 521(2): 441-448, http://dx.doi.org/10.1016/j.bbrc.2019.10.072.
[12] Duncan, Alexander, Heyer, Mary P, Ishikawa, Masago, Caligiuri, Stephanie P B, Liu, Xinan, Chen, Zuxin, Di Bonaventura, Maria Vittoria Micioni, Elayouby, Karim S, Ables, Jessica L, Howe, William M, Bali, Purva, Fillinger, Clementine, Williams, Maya, OConnor, Richard M, Wang, Zichen, Lu, Qun, Kamenecka, Theodore M, Maayan, Avi, ONeill, Heidi C, IbanezTallon, Ines, Geurts, Aron M, Kenny, Paul J. Habenular TCF7L2 links nicotine addiction to diabetes. NATURE[J]. 2019, 574(7778): 372-+, [13] Stefan Passlick, Ek Raj Thapaliya, Zuxin Chen, Matthew T Richers, Graham C R EllisDavies. Optical probing of acetylcholine receptors on neurons in the medial habenula with a novel caged nicotine drug analogue. THE JOURNAL OF PHYSIOLOGY[J]. 2018, 596(22): 5307-5318, [14] Chen, Zuxin, Kenny, Paul J. Endocannabinoid Signaling in the Habenula Regulates Adaptive Responses to Stress. BIOLOGICAL PSYCHIATRYnull. 2018, 84(8): 553-554, http://dx.doi.org/10.1016/j.biopsych.2018.08.001.
[15] Tuesta, Luis M, Chen, Zuxin, Duncan, Alexander, Fowler, Christie D, Ishikawa, Masago, Lee, Brian R, Liu, XinAn, Lu, Qun, Cameron, Michael, Hayes, Matthew R, Kamenecka, Theodore M, Pletcher, Matthew, Kenny, Paul J. GLP-1 acts on habenular avoidance circuits to control nicotine intake. NATURE NEUROSCIENCE[J]. 2017, 20(5): 708-+, [16] Chen, Zuxin, Das, Brati, Nakamura, Yukihiro, DiGregorio, David A, Young, Samuel M, Jr. Ca2+ Channel to Synaptic Vesicle Distance Accounts for the Readily Releasable Pool Kinetics at a Functionally Mature Auditory Synapse. JOURNAL OF NEUROSCIENCE[J]. 2015, 35(5): 2083-2100, http://dx.doi.org/10.1523/JNEUROSCI.2753-14.2015.
[17] Chen, Zuxin, Kenny, Paul J. Running on Empty: Leptin Signaling in VTA Regulates Reward from Physical Activity. CELL METABOLISMnull. 2015, 22(4): 540-541, http://dx.doi.org/10.1016/j.cmet.2015.09.021.
[18] Chen, Zuxin, Cooper, Benjamin, Kalla, Stefan, Varoqueaux, Frederique, Young, Samuel M, Jr. The Munc13 Proteins Differentially Regulate Readily Releasable Pool Dynamics and Calcium-Dependent Recovery at a Central Synapse. JOURNAL OF NEUROSCIENCE[J]. 2013, 33(19): 8336-8351, https://www.webofscience.com/wos/woscc/full-record/WOS:000318775200023.
[19] Montesinos, Monica S, Chen, Zuxin, Young, Samuel M, Jr. pUNISHER: a high-level expression cassette for use with recombinant viral vectors for rapid and long term in vivo neuronal expression in the CNS. JOURNAL OF NEUROPHYSIOLOGY[J]. 2011, 106(6): 3230-3244, https://www.webofscience.com/wos/woscc/full-record/WOS:000298345000041.
[20] Mingcong Chen, Zuxin Chen, Xiao Xiao, Libing Zhou, Rao Fu, Xian Jiang, Mao Pang, Jianxun Xia. Corticospinal circuit neuroplasticity may involve silent synapses: Implications for functional recovery facilitated by neuromodulation after spinal cord injury. IBRO NEUROSCIENCE REPORTS. http://dx.doi.org/10.1016/j.ibneur.2022.08.005.