代谢组学

   

070302-分析化学

色谱，质谱，代谢组学

2002-09--2009-01   中国科学院大连化学物理研究所   博士
1994-09--1998-07   大连理工大学   学士

博士研究生

博士学位

   

1998-08~现在, 中国科学院大连化学物理研究所, 副研究员

   

[1] 许国旺, 张雨晴, 赵欣捷, 刘心昱, 吕王洁, 胡春秀, 徐天润. 联合标志物及在诊断心房颤动中应用及诊断试剂或试剂盒. CN: CN115112776B, 2023-07-04.
[2] 许国旺, 张雨晴, 赵欣捷, 刘心昱, 吕王洁, 胡春秀, 徐天润. 联合标志物及在诊断心房颤动中应用及诊断试剂或试剂盒. CN: CN115112776A, 2022-09-27.
[3] 许国旺, 夏悦怡, 王肖肖, 马晨菲, 林晓惠, 路鑫, 赵春霞, 赵欣捷, 肖占敏. 基于液相色谱-高分辨质谱的石油分子表征数据处理方法. CN: CN114609258A, 2022-06-10.
[4] 许国旺, 李在芳, 夏悦怡, 张秀琼, 路鑫, 赵春霞, 赵欣捷. 一种植物中病虫害介导的植物抗性相关次生代谢物的鉴定方法. CN: CN114624340A, 2022-06-14.
[5] 许国旺, 王鑫欣, 亓彦鹏, 李在芳, 路鑫, 林晓惠, 赵春霞, 赵欣捷. 一种基于分子结构关联网络的规模化代谢组定性方法. CN: CN114609318A, 2022-06-10.
[6] 许国旺, 李在芳, 王鑫欣, 亓彦鹏, 路鑫, 林晓惠, 赵春霞, 赵欣捷. 一种代谢组深度注释方法. CN: CN114594171A, 2022-06-07.
[7] 许国旺, 王鑫欣, 王晓琳, 赵欣捷. 一组用于诊断儿童毛细支气管炎的联合标志物及其应用和检测试剂盒. CN: CN113552228A, 2021-10-26.
[8] 许国旺, 王鑫欣, 王晓琳, 赵欣捷. 一组用于诊断儿童哮喘病的联合标志物及其应用和检测试剂盒. CN: CN113552227A, 2021-10-26.
[9] 许国旺, 王砚凤, 轩秋慧, 欧阳瑒, 赵欣捷, 赵春霞, 路鑫. 一种组合标志物及其应用和检测试剂盒. CN: CN113155983A, 2021-07-23.
[10] 许国旺, 王砚凤, 轩秋慧, 欧阳瑒, 赵欣捷, 赵春霞, 路鑫. 一种组合标志物及其应用和检测试剂盒. CN: CN113155983B, 2023-04-11.
[11] 许国旺, 王利超, 赵欣捷, 刘心昱, 路鑫. 一种筛查糖尿病的联合型代谢标志物的应用及其试剂盒. CN: CN112903885A, 2021-06-04.
[12] 许国旺, 张秀琼, 李在芳, 郑福建, 赵春霞, 赵欣捷, 路鑫. 基于液相色谱-质谱的糖苷类化合物规模化定性方法. CN: CN112858492A, 2021-05-28.
[13] 许国旺, 轩秋慧, 欧阳瑒, 王砚凤, 赵欣捷, 胡春秀. 一种血清代谢标志物的用途及检测试剂盒. CN: CN112697889A, 2021-04-23.
[14] 许国旺, 轩秋慧, 欧阳瑒, 王砚凤, 赵欣捷, 胡春秀. 一种血清代谢标志物的用途及检测试剂盒. CN: CN112697889B, 2022-03-08.
[15] 许国旺, 欧阳瑒, 轩秋慧, 王砚凤, 赵欣捷. 用于糖尿病人群中视网膜病变诊断的联合标志物及试剂盒. CN: CN112198233A, 2021-01-08.
[16] 宁光, 王卫庆, 毕宇芳, 许国旺, 陆洁莉, 李勉, 赵欣捷, 王霜原, 徐瑜, 徐敏, 杜瑞, 王晓琳, 李琦. 胆汁酸联合标志物在制备用于预测或诊断糖尿病的检测试剂或检测物的用途. CN: CN110220987A, 2019-09-10.
[17] 许国旺, 王利超, 苏本哲, 赵欣捷, 曾仲大, 李超, 路鑫, 林晓慧. 一种拟靶向代谢组学分析的离子对挑选方法. CN: CN110579555A, 2019-12-17.
[18] 许国旺, 郑思佳, 赵欣捷, 王晴晴, 王晓琳. 一种用于诊断膀胱癌的联合标志物及试剂盒和应用. CN: CN109709220A, 2019-05-03.
[19] 许国旺, 周洋, 赵欣捷, 路鑫. 一种用于评价2型糖尿病的格列齐特适用性的血清组合标志物及其检测试剂盒. CN: CN109682909A, 2019-04-26.
[20] 许国旺, 邵亚平, 赵欣捷. 用于诊断前列腺癌的尿样组合标志物及检测试剂盒. CN: CN108344830B, 2020-10-16.
[21] 许国旺, 邵亚平, 赵欣捷. 用于诊断前列腺癌的尿样组合标志物及检测试剂盒和方法. CN: CN108344830A, 2018-07-31.
[22] 夏庆友, 许国旺, 陈全梅, 刘心昱, 赵萍, 孙艳慧, 赵欣捷. 甘氨酸或其代谢调节剂在提高家蚕丝产量中的应用及其方法. CN: CN103983726A, 2014-08-13.
[23] 许国旺, 李艳杰, 赵欣捷, 侯丽辉. 用于诊断多囊卵巢综合征的联合标志物、试剂盒和系统. CN: CN104777242A, 2015-07-15.
[24] 许国旺, 李佳, 赵欣捷, 陈世礼, 曾仲大, 路鑫. 一种脂质代谢网络动态研究的方法. CN: CN104063570A, 2014-09-24.
[25] 许国旺, 李佳, 赵欣捷, 路鑫. 基于液相色谱-质谱联用的大规模血浆鞘脂轮廓分析方法. CN: CN103884782A, 2014-06-25.
[26] 许国旺, 陈世礼, 李艳杰, 李佳, 赵欣捷, 路鑫. 一种用于微量组织中代谢物组和脂质组同时提取分析的方法. CN: CN103776911A, 2014-05-07.
[27] 尹沛源, 雷纳·莱曼, 黄强, 周丽娜, 赵欣捷, 路鑫, 许国旺. 一种判断用于科学研究的血液样本采集质量的方法. CN: CN103728379A, 2014-04-16.
[28] 孔宏伟, 王晓琳, 赵欣捷, 王文昭, 许国旺. 一种检测血中GCDCS和GCDCA的试剂盒. CN: CN102798672A, 2012-11-28.
[29] 许国旺, 李方楼, 赵欣捷. 一种硝化苯硼酸亲和色谱预柱及其制备和应用. CN: CN1939568A, 2007-04-04.
[30] 许国旺, 明平文, 杨凌, 刘中民, 张卓然, 赵春霞, 马磊, 许磊, 齐越, 孙承林, 韩秀文, 陈研, 曲振平, 缪少军, 郑丛龙, 赵欣捷, 杜逊甫, 刘波, 孔宏伟, 王畅, 叶芬, 胡刚, 刘宇新, 刘页, 张涛, 黄向阳, 包信和. 过滤、吸附及灭活病毒的纳米催化材料的快速筛选方法. CN: CN1261763C, 2006-06-28.
[31] 叶芬, 许国旺, 赵欣捷. 微量和痕量一氧化碳、二氧化碳气相色谱分析流程. CN: CN1384356A, 2002-12-11.
[32] 修正佳, 许国旺, 赵欣捷, 孔宏伟, 路鑫. 一种用于白酒质量监测的气相色谱毛细管柱其制备及应用. CN: CN1356548A, 2002-07-03.
[33] 叶芬, 路鑫, 赵欣捷, 孔宏伟, 许国旺. 一种工业色谱仪模拟系统. CN: CN1356547A, 2002-07-03.
[34] 路鑫, 张桐枫, 赵欣捷, 许国旺. 一种液氨催化制低级脂肪胺反应过程产物的分析方法. CN: CN1331414A, 2002-01-16.
[35] 叶芬, 孔宏伟, 路鑫, 赵欣捷, 许国旺. 一种甲苯歧化与烷基转移反应产物的在线分析方法. CN: CN1167951C, 2004-09-22.
[36] 叶芬, 路鑫, 赵欣捷, 孔宏伟, 许国旺. 对二甲苯液相催化氧化制对苯二甲酸反应过程产物分析方法. CN: CN1298102A, 2001-06-06.

   

[1] Han Bao, Jinhui Zhao, Xinjie Zhao, Chunxia Zhao, Xin Lu, Guowang Xu. Prediction of plant secondary metabolic pathways using deep transfer learning. BMC BIOINFORMATICS[J]. 2023, 24(1): 1-13, http://dx.doi.org/10.1186/s12859-023-05485-9.
[2] Lv, Wangjie, Zeng, Zhongda, Zhang, Yuqing, Wang, Qingqing, Wang, Lichao, Zhang, Zhaoxuan, Shi, Xianzhe, Zhao, Xinjie, Xu, Guowang. Comprehensive metabolite quantitative assay based on alternate metabolomics and lipidomics analyses. ANALYTICA CHIMICA ACTA[J]. 2022, 1215: [3] Hu, Chunxiu, Hoene, Miriam, Plomgaard, Peter, Hansen, Jakob S, Zhao, Xinjie, Li, Jia, Wang, Xiaolin, Clemmesen, Jens O, Secher, Niels H, Haering, Hans U, Lehmann, Rainer, Xu, Guowang, Weigert, Cora. Muscle-Liver Substrate Fluxes in Exercising Humans and Potential Effects on Hepatic Metabolism. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM[J]. 2020, 105(4): https://www.webofscience.com/wos/woscc/full-record/WOS:000525950100100.
[4] Xuan, Qiuhui, Zheng, Fujian, Yu, Di, Ouyang, Yang, Zhao, Xinjie, Hu, Chunxiu, Xu, Guowang. Rapid lipidomic profiling based on ultra-high performance liquid chromatography-mass spectrometry and its application in diabetic retinopathy. ANALYTICAL AND BIOANALYTICAL CHEMISTRY[J]. 2020, 412(15): 3585-3594, http://dx.doi.org/10.1007/s00216-020-02632-6.
[5] Sobhi, Hany F, Zhao, Xinjie, Plomgaard, Peter, Hoene, Miriam, Hansen, Jakob S, Karus, Benedikt, Niess, Andreas M, Haering, Hans U, Lehmann, Rainer, Adams, Sean H, Xu, Guowang, Weigert, Cora. Identification and regulation of the xenometabolite derivatives cis- and trans-3,4-methylene-heptanoylcarnitine in plasma and skeletal muscle of exercising humans. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM[J]. 2020, 318(5): E701-E709, https://www.webofscience.com/wos/woscc/full-record/WOS:000533521000013.
[6] Lv, Wangjie, Wang, Lichao, Xuan, Qiuhui, Zhao, Xinjie, Liu, Xinyu, Shi, Xianzhe, Xu, Guowang. Pseudotargeted Method Based on Parallel Column Two- Dimensional Liquid Chromatography-Mass Spectrometry for Broad Coverage of Metabolome and Lipidome. ANALYTICAL CHEMISTRY[J]. 2020, 92(8): 6043-6050, https://www.webofscience.com/wos/woscc/full-record/WOS:000527779200054.
[7] Zheng, Fujian, Zhao, Xinjie, Zeng, Zhongda, Wang, Lichao, Lv, Wangjie, Wang, Qingqing, Xu, Guowang. Development of a plasma pseudotargeted metabolomics method based on ultra-high-performance liquid chromatography-mass spectrometry. NATURE PROTOCOLS[J]. 2020, 15(8): 2519-2537, https://www.webofscience.com/wos/woscc/full-record/WOS:000543028200001.
[8] Chen, Di, Zhao, Xinjie, Sui, Zhigang, Niu, Huan, Chen, Luonan, Hu, Cheng, Xuan, Qiuhui, Hou, Xuhong, Zhang, Rong, Zhou, Lina, Li, Yanli, Yuan, Huiming, Zhang, Yukui, Wu, Jiarui, Zhang, Lihua, Wu, Renan, Piao, HaiLong, Xu, Guowang, Jia, Weiping. A multi-omics investigation of the molecular characteristics and classification of six metabolic syndrome relevant diseases. THERANOSTICS[J]. 2020, 10(5): 2029-2046, https://www.webofscience.com/wos/woscc/full-record/WOS:000508008300004.
[9] Ju, Ran, Liu, Xinyu, Zheng, Fujian, Zhao, Xinjie, Lu, Xin, Zeng, Zhongda, Lin, Xiaohui, Xu, Guowang. Removal of false positive features to generate authentic peak table for high-resolution mass spectrometry-based metabolomics study. ANALYTICA CHIMICA ACTA[J]. 2019, 1067: 79-87, http://cas-ir.dicp.ac.cn/handle/321008/165512.
[10] Yan, Min, Qi, Huan, Xia, Tian, Zhao, Xinjie, Wang, Wen, Wang, Zhichao, Lu, Chang, Ning, Zhen, Chen, Huan, Li, Tongming, Tekcham, Dinesh Singh, Liu, Xiumei, Liu, Jing, Chen, Di, Liu, Xiaolong, Xu, Guowang, Piao, Hailong. Metabolomics profiling of metformin-mediated metabolic reprogramming bypassing AMPK alpha. METABOLISM-CLINICAL AND EXPERIMENTAL[J]. 2019, 91: 18-29, https://www.webofscience.com/wos/woscc/full-record/WOS:000470301900003.
[11] Shao, Yaping, Ye, Guozhu, Ren, Shancheng, Piao, HaiLong, Zhao, Xinjie, Lu, Xin, Wang, Fubo, Ma, Wang, Li, Jia, Yin, Peiyuan, Xia, Tian, Xu, Chuanliang, Yu, Jane J, Sun, Yinghao, Xu, Guowang. Metabolomics and transcriptomics profiles reveal the dysregulation of the tricarboxylic acid cycle and related mechanisms in prostate cancer. INTERNATIONAL JOURNAL OF CANCER[J]. 2018, 143(2): 396-407, http://dx.doi.org/10.1002/ijc.31313.
[12] Wang, Shujie, Deng, Yuying, Xie, Xiaoyan, Ma, Jing, Xu, Min, Zhao, Xinjie, Gu, Weiqiong, Hong, Jie, Wang, Weiqing, Xu, Guowang, Ning, Guang, Gu, Yanyun, Zhang, Yifei. Plasma bile acid changes in type 2 diabetes correlated with insulin secretion in two-step hyperglycemic clamp. JOURNAL OF DIABETES[J]. 2018, 10(11): 874-885, http://cas-ir.dicp.ac.cn/handle/321008/166938.
[13] Zhou, Yang, Hu, Cheng, Zhao, Xinjie, Luo, Ping, Lu, Jingyi, Li, Qing, Chen, Miao, Yan, Dandan, Lu, Xin, Kong, Hongwei, Jia, Weiping, Xu, Guowang. Serum Metabolomics Study of Gliclazide-Modified-Release-Treated Type 2 Diabetes Mellitus Patients Using a Gas Chromatography-Mass Spectrometry Method. JOURNAL OF PROTEOME RESEARCH[J]. 2018, 17(4): 1575-1585, http://cas-ir.dicp.ac.cn/handle/321008/169160.
[14] Zhao, Xinjie, Zeng, Zhongda, Chen, Aiming, Lu, Xin, Zhao, Chunxia, Hu, Chunxiu, Zhou, Lina, Liu, Xinyu, Wang, Xiaolin, Hou, Xiaoli, Ye, Yaorui, Xu, Guowang. Comprehensive Strategy to Construct In-House Database for Accurate and Batch Identification of Small Molecular Metabolites. ANALYTICAL CHEMISTRY[J]. 2018, 90(12): 7635-7643, https://www.webofscience.com/wos/woscc/full-record/WOS:000436028800074.
[15] Xuan, Qiuhui, Hu, Chunxiu, Yu, Di, Wang, Lichao, Zhou, Yang, Zhao, Xinjie, Li, Qi, Hou, Xiaoli, Xu, Guowang. Development of a High Coverage Pseudotargeted Lipidomics Method Based on Ultra-High Performance Liquid Chromatography-Mass Spectrometry. ANALYTICAL CHEMISTRY[J]. 2018, 90(12): 7608-7616, http://dx.doi.org/10.1021/acs.analchem.8b01331.
[16] Wang, Lichao, Su, Benzhe, Zeng, Zhongda, Li, Chao, Zhao, Xinjie, Lv, Wangjie, Xuan, Qiuhui, Ouyang, Yang, Zhou, Lina, Yin, Peiyuan, Peng, Xiaojun, Lu, Xin, Lin, Xiaohui, Xu, Guowang. Ion-Pair Selection Method for Pseudotargeted Metabolomics Based on SWATH MS Acquisition and Its Application in Differential Metabolite Discovery of Type 2 Diabetes. ANALYTICAL CHEMISTRY[J]. 2018, 90(19): 11401-11408, http://cas-ir.dicp.ac.cn/handle/321008/166944.
[17] Yu, Di, Zhou, Lina, Xuan, Qiuhui, Wang, Lichao, Zhao, Xinjie, Lu, Xin, Xu, Guowang. Strategy for Comprehensive Identification of Acylcarnitines Based on Liquid Chromatography-High-Resolution Mass Spectrometry. ANALYTICAL CHEMISTRY[J]. 2018, 90(9): 5712-5718, http://cas-ir.dicp.ac.cn/handle/321008/167204.
[18] Li, Zaifang, Zhao, Chunxia, Zhao, Xinjie, Xia, Yueyi, Sun, Xiaoshan, Xie, Wenyan, Ye, Yaorui, Lu, Xin, Xu, Guowang. Deep Annotation of Hydroxycinnamic Acid Amides in Plants Based on Ultra-High-Performance Liquid Chromatography-High-Resolution Mass Spectrometry and Its In Silico Database. ANALYTICAL CHEMISTRY[J]. 2018, 90(24): 14321-14330, http://cas-ir.dicp.ac.cn/handle/321008/166358.
[19] Feng, Xiaoling, Chen, Lu, Li, Na, Zhao, Yan, Han, Qimao, Wang, Xiaolin, Wang, Wei, Ma, Liping, Zhao, Xinjie. Metabolomics biomarker analysis of threatened abortion in polycystic ovary syndrome: a clinical discovery study. RSC ADVANCES[J]. 2017, 7(83): 52923-52929, http://cas-ir.dicp.ac.cn/handle/321008/169274.
[20] Fu, Yanqing, Zhou, Zhihui, Kong, Hongwei, Lu, Xin, Zhao, Xinjie, Chen, Yihui, Chen, Jia, Wu, Zeming, Xu, Zhiliang, Zhao, Chunxia, Xu, Guowang. Nontargeted Screening Method for Illegal Additives Based on Ultrahigh-Performance Liquid Chromatography-High-Resolution Mass Spectrometry. ANALYTICAL CHEMISTRY[J]. 2016, 88(17): 8870-8877, http://cas-ir.dicp.ac.cn/handle/321008/170202.
[21] Yang, Jun, Zhao, Xinjie, Lu, Xin, Lin, Xiaohui, Xu, Guowang. A data preprocessing strategy for metabolomics to reduce the mask effect in data analysis. FRONTIERS IN MOLECULAR BIOSCIENCES[J]. 2015, 2: https://doaj.org/article/248ceff9166b44b9ba953be34194dae6.
[22] Chen, Quanmei, Liu, Xinyu, Zhao, Ping, Sun, Yanhui, Zhao, Xinjie, Xiong, Ying, Xu, Guowang, Xia, Qingyou. GC/MS-based metabolomic studies reveal key roles of glycine in regulating silk synthesis in silkworm, Bombyx mori. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY[J]. 2015, 57: 41-50, http://dx.doi.org/10.1016/j.ibmb.2014.12.007.
[23] Liu, Xinyu, Zheng, Peng, Zhao, Xinjie, Zhang, Yuqing, Hu, Chunxiu, Li, Jia, Zhao, Jieyu, Zhou, Jingjing, Xie, Peng, Xu, Guowang. Discovery and Validation of Plasma Biomarkers for Major Depressive Disorder Classification Based on Liquid Chromatography-Mass Spectrometry. JOURNAL OF PROTEOME RESEARCH[J]. 2015, 14(5): 2322-2330, http://cas-ir.dicp.ac.cn/handle/321008/146252.
[24] Shao, Yaping, Zhu, Bin, Zheng, Ruiyin, Zhao, Xinjie, Yin, Peiyuan, Lu, Xin, Jiao, Binghua, Xu, Guowang, Yao, Zhenzhen. Development of Urinary Pseudotargeted LC-MS-Based Metabolomics Method and Its Application in Hepatocellular Carcinoma Biomarker Discovery. JOURNAL OF PROTEOME RESEARCH[J]. 2015, 14(2): 906-916, http://dx.doi.org/10.1021/pr500973d.
[25] Huang, Yan, Chen, Guoyou, Liu, Xinyu, Shao, Yaping, Gao, Peng, Xin, Chenchen, Cui, Zhenze, Zhao, Xinjie, Xu, Guowang. Serum Metabolomics Study and Eicosanoid Analysis of Childhood Atopic Dermatitis Based on Liquid Chromatography-Mass Spectrometry. JOURNAL OF PROTEOME RESEARCH[J]. 2014, 13(12): 5715-5723, http://cas-ir.dicp.ac.cn/handle/321008/144196.
[26] Zhao, Xinjie, Chen, Jihong, Ye, Lei, Xu, Guowang. Serum Metabolomics Study of the Acute Graft Rejection in Human Renal Transplantation Based on Liquid Chromatography-Mass Spectrometry. JOURNAL OF PROTEOME RESEARCH[J]. 2014, 13(5): 2659-2667, http://cas-ir.dicp.ac.cn/handle/321008/144490.
[27] Zhao, Xinjie, Xu, Fang, Qi, Bing, Hao, Songli, Li, Yanjie, Li, Yan, Zou, Lihong, Lu, Caixia, Xu, Guowang, Hou, Lihui. Serum Metabolomics Study of Polycystic Ovary Syndrome Based on Liquid Chromatography-Mass Spectrometry. JOURNAL OF PROTEOME RESEARCH[J]. 2014, 13(2): 1101-1111, http://cas-ir.dicp.ac.cn/handle/321008/145531.
[28] Li, Yanjie, Song, Xue, Zhao, Xinjie, Zou, Lijuan, Xu, Guowang. Serum metabolic profiling study of lung cancer using ultra high performance liquid chromatography/quadrupole time-of-flight mass spectrometry. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES[J]. 2014, 966: 147-153, http://dx.doi.org/10.1016/j.jchromb.2014.04.047.
[29] Li Jia, Miriam Hoene, Zhao Xinjie, Chen Shili, Hai Wei, HansUlrich H, ring, Lin Xiaohui, Ceng Zhongda, Cora Weigert, Rainer Lehmann, Xu Guowang. Stable isotope-assisted lipidomics combined with nontargeted isotopomer filtering, a tool to unravel the complex dynamics of lipid metabolism. ANALYTICAL CHEMISTRY[J]. 2013, 85(9): 4651-, http://159.226.238.44/handle/321008/119636.
[30] Yin, Peiyuan, Peter, Andreas, Franken, Holger, Zhao, Xinjie, Neukamm, Sabine S, Rosenbaum, Lars, Lucio, Marianna, Zell, Andreas, Haering, HansUlrich, Xu, Guowang, Lehmann, Rainer. Preanalytical Aspects and Sample Quality Assessment in Metabolomics Studies of Human Blood. CLINICAL CHEMISTRY[J]. 2013, 59(5): 833-845, http://www.irgrid.ac.cn/handle/1471x/858656.
[31] Li, Jia, Hu, Chunxiu, Zhao, Xinjie, Dai, Weidong, Chen, Shili, Lu, Xin, Xu, Guowang. Large-scaled human serum sphingolipid profiling by using reversed-phase liquid chromatography coupled with dynamic multiple reaction monitoring of mass spectrometry: Method development and application in hepatocellular carcinoma. JOURNAL OF CHROMATOGRAPHY A[J]. 2013, 1320: 103-110, http://dx.doi.org/10.1016/j.chroma.2013.10.064.
[32] Chen, Shili, Yin, Peiyuan, Zhao, Xinjie, Xing, Wenbin, Hu, Chunxiu, Zhou, Lina, Xu, Guowang. Serum lipid profiling of patients with chronic hepatitis B, cirrhosis, and hepatocellular carcinoma by ultra fast LC/IT-TOF MS. ELECTROPHORESIS[J]. 2013, 34(19): 2848-2856, http://dx.doi.org/10.1002/elps.201200629.
[33] Chen, Shili, Hoene, Miriam, Li, Jia, Li, Yanjie, Zhao, Xinjie, Haering, HansUlrich, Schleicher, Erwin D, Weigert, Cora, Xu, Guowang, Lehmann, Rainer. Simultaneous extraction of metabolome and lipidome with methyl tert-butyl ether from a single small tissue sample for ultra-high performance liquid chromatography/mass spectrometry. JOURNAL OF CHROMATOGRAPHY A[J]. 2013, 1298: 9-16, http://dx.doi.org/10.1016/j.chroma.2013.05.019.
[34] Wolf, Magnus, Chen, Shili, Zhao, Xinjie, Scheler, Mika, Irmler, Martin, Staiger, Harald, Beckers, Johannes, de Angelis, Martin Hrabe, Fritsche, Andreas, Haring, HansUlrich, Schleicher, Erwin D, Xu, Guowang, Lehmann, Rainer, Weigert, Cora. Production and Release of Acylcarnitines by Primary Myotubes Reflect the Differences in Fasting Fat Oxidation of the Donors. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM[J]. 2013, 98(6): E1137-E1142, http://www.irgrid.ac.cn/handle/1471x/858644.

   

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