基本信息
赵欣捷  女  硕导  中国科学院大连化学物理研究所
电子邮件: xj_zhao1@126.com
通信地址: 大连市中山路457号
邮政编码:

研究领域

代谢组学

招生信息

   
招生专业
070302-分析化学
招生方向
色谱,质谱,代谢组学

教育背景

2002-09--2009-01   中国科学院大连化学物理研究所   博士
1994-09--1998-07   大连理工大学   学士
学历
博士研究生
学位
博士学位

工作经历

   
工作简历
1998-08~现在, 中国科学院大连化学物理研究所, 副研究员

专利与奖励

   
专利成果
[1] 许国旺, 张雨晴, 赵欣捷, 刘心昱, 吕王洁, 胡春秀, 徐天润. 联合标志物及在诊断心房颤动中应用及诊断试剂或试剂盒. CN: CN115112776B, 2023-07-04.
[2] 许国旺, 张雨晴, 赵欣捷, 刘心昱, 吕王洁, 胡春秀, 徐天润. 联合标志物及在诊断心房颤动中应用及诊断试剂或试剂盒. CN: CN115112776A, 2022-09-27.
[3] 许国旺, 夏悦怡, 王肖肖, 马晨菲, 林晓惠, 路鑫, 赵春霞, 赵欣捷, 肖占敏. 基于液相色谱-高分辨质谱的石油分子表征数据处理方法. CN: CN114609258A, 2022-06-10.
[4] 许国旺, 李在芳, 夏悦怡, 张秀琼, 路鑫, 赵春霞, 赵欣捷. 一种植物中病虫害介导的植物抗性相关次生代谢物的鉴定方法. CN: CN114624340A, 2022-06-14.
[5] 许国旺, 王鑫欣, 亓彦鹏, 李在芳, 路鑫, 林晓惠, 赵春霞, 赵欣捷. 一种基于分子结构关联网络的规模化代谢组定性方法. CN: CN114609318A, 2022-06-10.
[6] 许国旺, 李在芳, 王鑫欣, 亓彦鹏, 路鑫, 林晓惠, 赵春霞, 赵欣捷. 一种代谢组深度注释方法. CN: CN114594171A, 2022-06-07.
[7] 许国旺, 王鑫欣, 王晓琳, 赵欣捷. 一组用于诊断儿童毛细支气管炎的联合标志物及其应用和检测试剂盒. CN: CN113552228A, 2021-10-26.
[8] 许国旺, 王鑫欣, 王晓琳, 赵欣捷. 一组用于诊断儿童哮喘病的联合标志物及其应用和检测试剂盒. CN: CN113552227A, 2021-10-26.
[9] 许国旺, 王砚凤, 轩秋慧, 欧阳瑒, 赵欣捷, 赵春霞, 路鑫. 一种组合标志物及其应用和检测试剂盒. CN: CN113155983A, 2021-07-23.
[10] 许国旺, 王砚凤, 轩秋慧, 欧阳瑒, 赵欣捷, 赵春霞, 路鑫. 一种组合标志物及其应用和检测试剂盒. CN: CN113155983B, 2023-04-11.
[11] 许国旺, 王利超, 赵欣捷, 刘心昱, 路鑫. 一种筛查糖尿病的联合型代谢标志物的应用及其试剂盒. CN: CN112903885A, 2021-06-04.
[12] 许国旺, 张秀琼, 李在芳, 郑福建, 赵春霞, 赵欣捷, 路鑫. 基于液相色谱-质谱的糖苷类化合物规模化定性方法. CN: CN112858492A, 2021-05-28.
[13] 许国旺, 轩秋慧, 欧阳瑒, 王砚凤, 赵欣捷, 胡春秀. 一种血清代谢标志物的用途及检测试剂盒. CN: CN112697889A, 2021-04-23.
[14] 许国旺, 轩秋慧, 欧阳瑒, 王砚凤, 赵欣捷, 胡春秀. 一种血清代谢标志物的用途及检测试剂盒. CN: CN112697889B, 2022-03-08.
[15] 许国旺, 欧阳瑒, 轩秋慧, 王砚凤, 赵欣捷. 用于糖尿病人群中视网膜病变诊断的联合标志物及试剂盒. CN: CN112198233A, 2021-01-08.
[16] 宁光, 王卫庆, 毕宇芳, 许国旺, 陆洁莉, 李勉, 赵欣捷, 王霜原, 徐瑜, 徐敏, 杜瑞, 王晓琳, 李琦. 胆汁酸联合标志物在制备用于预测或诊断糖尿病的检测试剂或检测物的用途. CN: CN110220987A, 2019-09-10.
[17] 许国旺, 王利超, 苏本哲, 赵欣捷, 曾仲大, 李超, 路鑫, 林晓慧. 一种拟靶向代谢组学分析的离子对挑选方法. CN: CN110579555A, 2019-12-17.
[18] 许国旺, 郑思佳, 赵欣捷, 王晴晴, 王晓琳. 一种用于诊断膀胱癌的联合标志物及试剂盒和应用. CN: CN109709220A, 2019-05-03.
[19] 许国旺, 周洋, 赵欣捷, 路鑫. 一种用于评价2型糖尿病的格列齐特适用性的血清组合标志物及其检测试剂盒. CN: CN109682909A, 2019-04-26.
[20] 许国旺, 邵亚平, 赵欣捷. 用于诊断前列腺癌的尿样组合标志物及检测试剂盒. CN: CN108344830B, 2020-10-16.
[21] 许国旺, 邵亚平, 赵欣捷. 用于诊断前列腺癌的尿样组合标志物及检测试剂盒和方法. CN: CN108344830A, 2018-07-31.
[22] 夏庆友, 许国旺, 陈全梅, 刘心昱, 赵萍, 孙艳慧, 赵欣捷. 甘氨酸或其代谢调节剂在提高家蚕丝产量中的应用及其方法. CN: CN103983726A, 2014-08-13.
[23] 许国旺, 李艳杰, 赵欣捷, 侯丽辉. 用于诊断多囊卵巢综合征的联合标志物、试剂盒和系统. CN: CN104777242A, 2015-07-15.
[24] 许国旺, 李佳, 赵欣捷, 陈世礼, 曾仲大, 路鑫. 一种脂质代谢网络动态研究的方法. CN: CN104063570A, 2014-09-24.
[25] 许国旺, 李佳, 赵欣捷, 路鑫. 基于液相色谱-质谱联用的大规模血浆鞘脂轮廓分析方法. CN: CN103884782A, 2014-06-25.
[26] 许国旺, 陈世礼, 李艳杰, 李佳, 赵欣捷, 路鑫. 一种用于微量组织中代谢物组和脂质组同时提取分析的方法. CN: CN103776911A, 2014-05-07.
[27] 尹沛源, 雷纳·莱曼, 黄强, 周丽娜, 赵欣捷, 路鑫, 许国旺. 一种判断用于科学研究的血液样本采集质量的方法. CN: CN103728379A, 2014-04-16.
[28] 孔宏伟, 王晓琳, 赵欣捷, 王文昭, 许国旺. 一种检测血中GCDCS和GCDCA的试剂盒. CN: CN102798672A, 2012-11-28.
[29] 许国旺, 李方楼, 赵欣捷. 一种硝化苯硼酸亲和色谱预柱及其制备和应用. CN: CN1939568A, 2007-04-04.
[30] 许国旺, 明平文, 杨凌, 刘中民, 张卓然, 赵春霞, 马磊, 许磊, 齐越, 孙承林, 韩秀文, 陈研, 曲振平, 缪少军, 郑丛龙, 赵欣捷, 杜逊甫, 刘波, 孔宏伟, 王畅, 叶芬, 胡刚, 刘宇新, 刘页, 张涛, 黄向阳, 包信和. 过滤、吸附及灭活病毒的纳米催化材料的快速筛选方法. CN: CN1261763C, 2006-06-28.
[31] 叶芬, 许国旺, 赵欣捷. 微量和痕量一氧化碳、二氧化碳气相色谱分析流程. CN: CN1384356A, 2002-12-11.
[32] 修正佳, 许国旺, 赵欣捷, 孔宏伟, 路鑫. 一种用于白酒质量监测的气相色谱毛细管柱其制备及应用. CN: CN1356548A, 2002-07-03.
[33] 叶芬, 路鑫, 赵欣捷, 孔宏伟, 许国旺. 一种工业色谱仪模拟系统. CN: CN1356547A, 2002-07-03.
[34] 路鑫, 张桐枫, 赵欣捷, 许国旺. 一种液氨催化制低级脂肪胺反应过程产物的分析方法. CN: CN1331414A, 2002-01-16.
[35] 叶芬, 孔宏伟, 路鑫, 赵欣捷, 许国旺. 一种甲苯歧化与烷基转移反应产物的在线分析方法. CN: CN1167951C, 2004-09-22.
[36] 叶芬, 路鑫, 赵欣捷, 孔宏伟, 许国旺. 对二甲苯液相催化氧化制对苯二甲酸反应过程产物分析方法. CN: CN1298102A, 2001-06-06.

出版信息

   
发表论文
[1] Han Bao, Jinhui Zhao, Xinjie Zhao, Chunxia Zhao, Xin Lu, Guowang Xu. Prediction of plant secondary metabolic pathways using deep transfer learning. BMC BIOINFORMATICS[J]. 2023, 第 3 作者24(1): 1-13, http://dx.doi.org/10.1186/s12859-023-05485-9.
[2] Analytical Chemistry. 2022,   通讯作者  
[3] Lv, Wangjie, Zeng, Zhongda, Zhang, Yuqing, Wang, Qingqing, Wang, Lichao, Zhang, Zhaoxuan, Shi, Xianzhe, Zhao, Xinjie, Xu, Guowang. Comprehensive metabolite quantitative assay based on alternate metabolomics and lipidomics analyses. ANALYTICA CHIMICA ACTA[J]. 2022, 第 8 作者  通讯作者  1215: 
[4] Zheng, Fujian, You, Lei, Qin, Wangshu, Ouyang, Runze, Lv, Wangjie, Guo, Lei, Lu, Xin, Li, Enyou, Zhao, Xinjie, Xu, Guowang. MetEx: A Targeted Extraction Strategy for Improving the Coverage and Accuracy of Metabolite Annotation in Liquid Chromatography-High-Resolution Mass Spectrometry Data. ANALYTICAL CHEMISTRY[J]. 2022, 第 9 作者  通讯作者  94(24): 8561-8569, http://dx.doi.org/10.1021/acs.analchem.1c04783.
[5] 李在芳, 郑福建, 夏悦怡, 张秀琼, 王鑫欣, 赵春霞, 赵欣捷, 路鑫, 许国旺. 基于修饰组和探针分子的重要途径代谢物筛选和注释新方法. 色谱[J]. 2022, 第 7 作者40(9): 788-796, http://lib.cqvip.com/Qikan/Article/Detail?id=7108017437.
[6] Obesity. 2021,   通讯作者  
[7] 张晗, 侯丽辉, 张春兰, 赵欣捷, 许国旺, 刘颖华. 基于代谢组学探索多囊卵巢综合征合并非酒精性脂肪性肝病的病因学研究. 中国妇幼保健[J]. 2021, 第 4 作者36(11): 2473-2478, http://lib.cqvip.com/Qikan/Article/Detail?id=7104915685.
[8] Ouyang, Yang, Qiu, Gaokun, Zhao, Xinjie, Su, Benzhe, Feng, Disheng, Lv, Wangjie, Xuan, Qiuhui, Wang, Lichao, Yu, Di, Wang, Qingqing, Lin, Xiaohui, Wu, Tangchun, Xu, Guowang. Metabolome-Genome-Wide Association Study (mGWAS) Reveals Novel Metabolites Associated with Future Type 2 Diabetes Risk and Susceptibility Loci in a Case-Control Study in a Chinese Prospective Cohort. GLOBAL CHALLENGES[J]. 2021, 第 3 作者5(4): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025395/.
[9] Zheng, Sijia, Zhang, Xiuqiong, Li, Zaifang, Hoene, Miriam, Fritsche, Louise, Zheng, Fujian, Li, Qi, Fritsche, Andreas, Peter, Andreas, Lehmann, Rainer, Zhao, Xinjie, Xu, Guowang. Systematic, Modifying Group-Assisted Strategy Expanding Coverage of Metabolite Annotation in Liquid Chromatography-Mass Spectrometry-Based Nontargeted Metabolomics Studies. ANALYTICAL CHEMISTRY[J]. 2021, 第 11 作者  通讯作者  93(31): 10916-10924, http://dx.doi.org/10.1021/acs.analchem.1c01715.
[10] Wang, Lichao, Zhang, Yinan, Liu, Xinyu, Zhao, Xinjie, Ouyang, Yang, Qiu, Gaokun, Lv, Wangjie, Zheng, Fujian, Wang, QingQing, Lu, Xin, Peng, Xiaojun, Wu, Tangchun, Lehmann, Rainer, Wang, Congrong, Jia, Weiping, Xu, Guowang. Metabolite Triplet in Serum Improves the Diagnostic Accuracy of Prediabetes and Diabetes Screening. JOURNAL OF PROTEOME RESEARCH[J]. 2021, 第 4 作者20(1): 1005-1014, https://www.webofscience.com/wos/woscc/full-record/WOS:000605145400087.
[11] Zhang, Yuqing, Xie, Yunpeng, Lv, Wangjie, Hu, Chunxiu, Xu, Tianrun, Liu, Xinyu, Zhang, Rongfeng, Xu, Guowang, Xia, Yunlong, Zhao, Xinjie. A high throughput lipidomics method and its application in atrial fibrillation based on 96-well plate pretreatment and liquid chromatography-mass spectrometry. JOURNAL OF CHROMATOGRAPHY A[J]. 2021, 第 10 作者  通讯作者  1651: http://dx.doi.org/10.1016/j.chroma.2021.462271.
[12] Lu, Jieli, Wang, Shuangyuan, Li, Mian, Gao, Zhengnan, Xu, Yu, Zhao, Xinjie, Hu, Chunyan, Zhang, Yi, Liu, Ruixin, Hu, Ruying, Shi, Lixin, Zheng, Ruizhi, Du, Rui, Su, Qing, Wang, Jiqiu, Chen, Yuhong, Yu, Xuefeng, Yan, Li, Wang, Tiange, Zhao, Zhiyun, Wang, Xiaolin, Li, Qi, Qin, Guijun, Wan, Qin, Chen, Gang, Xu, Min, Dai, Meng, Zhang, Di, Tang, Xulei, Wang, Guixia, Shen, Feixia, Luo, Zuojie, Qin, Yingfen, Chen, Li, Huo, Yanan, Li, Qiang, Ye, Zhen, Zhang, Yinfei, Liu, Chao, Wang, Youmin, Wu, Shengli, Yang, Tao, Deng, Huacong, Li, Donghui, Lai, Shenghan, Mu, Yiming, Chen, Lulu, Zhao, Jiajun, Xu, Guowang, Ning, Guang, Bi, Yufang, Wang, Weiqing, 4C Study Grp. Association of Serum Bile Acids Profile and Pathway Dysregulation With the Risk of Developing Diabetes Among Normoglycemic Chinese Adults: Findings From the 4C Study. DIABETES CARE[J]. 2021, 第 6 作者44(2): 499-510, http://dx.doi.org/10.2337/dc20-0884.
[13] Ouyang Yang, Chi Lei, Xu Chao, Zhao Xinjie, Cui Zhenze. Liquid chromatography. mass spectrometry-based metabolomics study of the efficacy of Chinese medicine asthma-relieving decoction on respiratory syncytial virus infection. CHINESE JOURNAL OF CHROMATOGRAPHY[J]. 2021, 第 4 作者  通讯作者  39(3): 281-290, http://dx.doi.org/10.3724/SP.J.1123.2020.06013.
[14] Analytical Chemistry. 2021,   通讯作者  
[15] Hu, Chunxiu, Hoene, Miriam, Plomgaard, Peter, Hansen, Jakob S, Zhao, Xinjie, Li, Jia, Wang, Xiaolin, Clemmesen, Jens O, Secher, Niels H, Haering, Hans U, Lehmann, Rainer, Xu, Guowang, Weigert, Cora. Muscle-Liver Substrate Fluxes in Exercising Humans and Potential Effects on Hepatic Metabolism. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM[J]. 2020, 第 5 作者105(4): https://www.webofscience.com/wos/woscc/full-record/WOS:000525950100100.
[16] Xuan, Qiuhui, Zheng, Fujian, Yu, Di, Ouyang, Yang, Zhao, Xinjie, Hu, Chunxiu, Xu, Guowang. Rapid lipidomic profiling based on ultra-high performance liquid chromatography-mass spectrometry and its application in diabetic retinopathy. ANALYTICAL AND BIOANALYTICAL CHEMISTRY[J]. 2020, 第 5 作者412(15): 3585-3594, http://dx.doi.org/10.1007/s00216-020-02632-6.
[17] Sobhi, Hany F, Zhao, Xinjie, Plomgaard, Peter, Hoene, Miriam, Hansen, Jakob S, Karus, Benedikt, Niess, Andreas M, Haering, Hans U, Lehmann, Rainer, Adams, Sean H, Xu, Guowang, Weigert, Cora. Identification and regulation of the xenometabolite derivatives cis- and trans-3,4-methylene-heptanoylcarnitine in plasma and skeletal muscle of exercising humans. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM[J]. 2020, 第 2 作者318(5): E701-E709, https://www.webofscience.com/wos/woscc/full-record/WOS:000533521000013.
[18] Lv, Wangjie, Wang, Lichao, Xuan, Qiuhui, Zhao, Xinjie, Liu, Xinyu, Shi, Xianzhe, Xu, Guowang. Pseudotargeted Method Based on Parallel Column Two- Dimensional Liquid Chromatography-Mass Spectrometry for Broad Coverage of Metabolome and Lipidome. ANALYTICAL CHEMISTRY[J]. 2020, 第 4 作者92(8): 6043-6050, https://www.webofscience.com/wos/woscc/full-record/WOS:000527779200054.
[19] Zheng, Fujian, Zhao, Xinjie, Zeng, Zhongda, Wang, Lichao, Lv, Wangjie, Wang, Qingqing, Xu, Guowang. Development of a plasma pseudotargeted metabolomics method based on ultra-high-performance liquid chromatography-mass spectrometry. NATURE PROTOCOLS[J]. 2020, 第 2 作者15(8): 2519-2537, https://www.webofscience.com/wos/woscc/full-record/WOS:000543028200001.
[20] Chen, Di, Zhao, Xinjie, Sui, Zhigang, Niu, Huan, Chen, Luonan, Hu, Cheng, Xuan, Qiuhui, Hou, Xuhong, Zhang, Rong, Zhou, Lina, Li, Yanli, Yuan, Huiming, Zhang, Yukui, Wu, Jiarui, Zhang, Lihua, Wu, Renan, Piao, HaiLong, Xu, Guowang, Jia, Weiping. A multi-omics investigation of the molecular characteristics and classification of six metabolic syndrome relevant diseases. THERANOSTICS[J]. 2020, 第 2 作者10(5): 2029-2046, https://www.webofscience.com/wos/woscc/full-record/WOS:000508008300004.
[21] Yifei Zhang, Yanyun Gu, Huahui Ren, Shujie Wang, Huanzi Zhong, Xinjie Zhao, Jing Ma, Xuejiang Gu, Yaoming Xue, Shan Huang, Jialin Yang, Li Chen, Gang Chen, Shen Qu, Jun Liang, Li Qin, Qin Huang, Yongde Peng, Qi Li, Xiaolin Wang, Ping Kong, Guixue Hou, Mengyu Gao, Zhun Shi, Xuelin Li, Yixuan Qiu, Yuanqiang Zou, Huanming Yang, Jian Wang, Guowang Xu, Shenghan Lai, Junhua Li, Guang Ning, Weiqing Wang. Gut microbiome-related effects of berberine and probiotics on type 2 diabetes (the PREMOTE study). NATURE COMMUNICATIONS[J]. 2020, 第 6 作者11(1): http://dx.doi.org/10.1038/s41467-020-18414-8.
[22] Ju, Ran, Liu, Xinyu, Zheng, Fujian, Zhao, Xinjie, Lu, Xin, Lin, Xiaohui, Zeng, Zhongda, Xu, Guowang. A graph density-based strategy for features fusion from different peak extract software to achieve more metabolites in metabolic profiling from high-resolution mass spectrometry. ANALYTICA CHIMICA ACTA[J]. 2020, 第 4 作者1139: 8-14, http://dx.doi.org/10.1016/j.aca.2020.09.029.
[23] Franko, Andras, Shao, Yaping, Heni, Martin, Hennenlotter, Joerg, Hoene, Miriam, Hu, Chunxiu, Liu, Xinyu, Zhao, Xinjie, Wang, Qingqing, Birkenfeld, Andreas L, Todenhoefer, Tilman, Stenzl, Arnulf, Peter, Andreas, Haering, HansUlrich, Lehmann, Rainer, Xu, Guowang, Lutz, Stefan Z. Human Prostate Cancer Is Characterized by an Increase in Urea Cycle Metabolites. CANCERS[J]. 2020, 第 8 作者12(7): https://doaj.org/article/2d93dba4fbff48f88360a756cf2b7726.
[24] Yu, Di, Xuan, Qiuhui, Zhang, Chaoqi, Hu, Chunxiu, Li, Yanli, Zhao, Xinjie, Liu, Shasha, Ren, Feifei, Zhang, Yi, Zhou, Lina, Xu, Guowang. Metabolic Alterations Related to Glioma Grading Based on Metabolomics and Lipidomics Analyses. METABOLITES[J]. 2020, 第 6 作者10(12): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760389/.
[25] Xuan, Qiuhui, Ouyang, Yang, Wang, Yanfeng, Wu, Liang, Li, Huating, Luo, Yuanyuan, Zhao, Xinjie, Feng, Disheng, Qin, Wangshu, Hu, Chunxiu, Zhou, Lina, Liu, Xinyu, Zou, Haidong, Cai, Chun, Wu, Jiarui, Jia, Weiping, Xu, Guowang. Multiplatform Metabolomics Reveals Novel Serum Metabolite Biomarkers in Diabetic Retinopathy Subjects. ADVANCED SCIENCE[J]. 2020, 第 7 作者7(22): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675050/.
[26] Ju, Ran, Liu, Xinyu, Zheng, Fujian, Zhao, Xinjie, Lu, Xin, Zeng, Zhongda, Lin, Xiaohui, Xu, Guowang. Removal of false positive features to generate authentic peak table for high-resolution mass spectrometry-based metabolomics study. ANALYTICA CHIMICA ACTA[J]. 2019, 第 4 作者1067: 79-87, http://cas-ir.dicp.ac.cn/handle/321008/165512.
[27] Yan, Min, Qi, Huan, Xia, Tian, Zhao, Xinjie, Wang, Wen, Wang, Zhichao, Lu, Chang, Ning, Zhen, Chen, Huan, Li, Tongming, Tekcham, Dinesh Singh, Liu, Xiumei, Liu, Jing, Chen, Di, Liu, Xiaolong, Xu, Guowang, Piao, Hailong. Metabolomics profiling of metformin-mediated metabolic reprogramming bypassing AMPK alpha. METABOLISM-CLINICAL AND EXPERIMENTAL[J]. 2019, 第 4 作者91: 18-29, https://www.webofscience.com/wos/woscc/full-record/WOS:000470301900003.
[28] Shao, Yaping, Ye, Guozhu, Ren, Shancheng, Piao, HaiLong, Zhao, Xinjie, Lu, Xin, Wang, Fubo, Ma, Wang, Li, Jia, Yin, Peiyuan, Xia, Tian, Xu, Chuanliang, Yu, Jane J, Sun, Yinghao, Xu, Guowang. Metabolomics and transcriptomics profiles reveal the dysregulation of the tricarboxylic acid cycle and related mechanisms in prostate cancer. INTERNATIONAL JOURNAL OF CANCER[J]. 2018, 第 5 作者143(2): 396-407, http://dx.doi.org/10.1002/ijc.31313.
[29] Wang, Shujie, Deng, Yuying, Xie, Xiaoyan, Ma, Jing, Xu, Min, Zhao, Xinjie, Gu, Weiqiong, Hong, Jie, Wang, Weiqing, Xu, Guowang, Ning, Guang, Gu, Yanyun, Zhang, Yifei. Plasma bile acid changes in type 2 diabetes correlated with insulin secretion in two-step hyperglycemic clamp. JOURNAL OF DIABETES[J]. 2018, 第 6 作者10(11): 874-885, http://cas-ir.dicp.ac.cn/handle/321008/166938.
[30] Zhou, Yang, Hu, Cheng, Zhao, Xinjie, Luo, Ping, Lu, Jingyi, Li, Qing, Chen, Miao, Yan, Dandan, Lu, Xin, Kong, Hongwei, Jia, Weiping, Xu, Guowang. Serum Metabolomics Study of Gliclazide-Modified-Release-Treated Type 2 Diabetes Mellitus Patients Using a Gas Chromatography-Mass Spectrometry Method. JOURNAL OF PROTEOME RESEARCH[J]. 2018, 第 3 作者17(4): 1575-1585, http://cas-ir.dicp.ac.cn/handle/321008/169160.
[31] Fu, Lihong, Qiu, Yixuan, Shen, Linyan, Cui, Canqi, Wang, Shuang, Wang, Shujie, Xie, Yun, Zhao, Xinjie, Gao, Xianfu, Ning, Guang, Nie, Aifang, Gu, Yanyun. The delayed effects of antibiotics in type 2 diabetes, friend or foe?. JOURNAL OF ENDOCRINOLOGY[J]. 2018, 第 8 作者238(2): 137-149, https://www.webofscience.com/wos/woscc/full-record/WOS:000438707700008.
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[37] Zheng SiJia, Wang QingQing, Wang XiaoLin, Zhao XinJie, Xu GuoWang. Hydrophilic Interaction Liquid Chromatography Coupled with Mass Spectrometry for Serum Metabolomics Analysis of Bladder Cancer. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY[J]. 2017, 第 4 作者  通讯作者  45(12): 1921-1929, http://cas-ir.dicp.ac.cn/handle/321008/168482.
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[75] Chen, Shili, Hoene, Miriam, Li, Jia, Li, Yanjie, Zhao, Xinjie, Haering, HansUlrich, Schleicher, Erwin D, Weigert, Cora, Xu, Guowang, Lehmann, Rainer. Simultaneous extraction of metabolome and lipidome with methyl tert-butyl ether from a single small tissue sample for ultra-high performance liquid chromatography/mass spectrometry. JOURNAL OF CHROMATOGRAPHY A[J]. 2013, 第 5 作者1298: 9-16, http://dx.doi.org/10.1016/j.chroma.2013.05.019.
[76] Wolf, Magnus, Chen, Shili, Zhao, Xinjie, Scheler, Mika, Irmler, Martin, Staiger, Harald, Beckers, Johannes, de Angelis, Martin Hrabe, Fritsche, Andreas, Haring, HansUlrich, Schleicher, Erwin D, Xu, Guowang, Lehmann, Rainer, Weigert, Cora. Production and Release of Acylcarnitines by Primary Myotubes Reflect the Differences in Fasting Fat Oxidation of the Donors. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM[J]. 2013, 第 3 作者98(6): E1137-E1142, http://www.irgrid.ac.cn/handle/1471x/858644.
[77] Li, Jia, Hoene, Miriam, Zhao, Xinjie, Chen, Shili, Wei, Hai, Haering, HansUlrich, Lin, Xiaohui, Zeng, Zhongda, Weigert, Cora, Lehmann, Rainer, Xu, Guowang. Stable lsotope-Assisted Lipidomics Combined with Nontargeted lsotopomer Filtering, a Tool to Unravel the Complex Dynamics of Lipid Metabolism. ANALYTICAL CHEMISTRY[J]. 2013, 第 3 作者85(9): 4651-4657, http://dx.doi.org/10.1021/ac400293y.
[78] 许国旺, 赵欣捷, 尹沛源, 胡春秀, 孔宏伟, 路鑫. LC-MS Based Metabolomics and Its Applications in Health Related Studies. THE FOURTEENTH INTERNATIONAL SYMPOSIUM ON ELECTROANALYTICAL CHEMISTRY. 2013, 第 2 作者60, http://159.226.238.44/handle/321008/116893.
[79] Li, Xiang, Hansen, Jakob, Zhao, Xinjie, Lu, Xin, Weigert, Cora, Haering, HansUlrich, Pedersen, Bente K, Plomgaard, Peter, Lehmann, Rainer, Xu, Guowang. Independent component analysis in non-hypothesis driven metabolomics: Improvement of pattern discovery and simplification of biological data interpretation demonstrated with plasma samples of exercising humans. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES[J]. 2012, 第 3 作者910: 156-162, http://dx.doi.org/10.1016/j.jchromb.2012.06.030.
[80] 许国旺, 赵欣捷, 尹沛源, 陈静, 吴泽明, 路鑫. Metabolomics opens a window to investigate the biological function of small molecules. 29TH INTERNATIONAL SYMPOSIUM ON CHROMATOGRAPHY. 2012, 第 2 作者8, http://159.226.238.44/handle/321008/117060.
[81] Chen, Jihong, Wen, Hao, Liu, Jian, Yu, Che, Zhao, Xinjie, Shi, Xianzhe, Xu, Guowang. Metabonomics study of the acute graft rejection in rat renal transplantation using reversed-phase liquid chromatography and hydrophilic interaction chromatography coupled with mass spectrometry. MOLECULAR BIOSYSTEMS[J]. 2012, 第 5 作者  通讯作者  8(3): 871-878, http://dx.doi.org/10.1039/c2mb05454j.
[82] 胡春秀, 陈世礼, 李佳, 赵欣捷, 赵素敏, 路鑫, 许国旺. Lipidomics in disease biomarker discovery: methods and applications. 36TH INTERNATIONAL SYMPOSIUM ON CAPILLARY CHROMATOGRAPHY AND THE 9TH GCXGC SYMPOSIUM. 2012, 第 4 作者18, http://159.226.238.44/handle/321008/116994.
[83] 戴伟东, 黄强, 赵欣捷, 孔宏伟, 尹沛源, 路鑫, 许国旺. Microfluidic Systems for Biomarker Analysis Integrating Solid-Phase Extraction, Labeling and Separation. THE 38TH INTERNATIONAL SYMPOSIUM ON HIGH PERFORMANCE LIQUID PHASE SEPARATIONS AND RELATED TECHNIQUES. 2012, 第 3 作者32, http://159.226.238.44/handle/321008/117052.
[84] Tan, Yexiong, Yin, Peiyuan, Tang, Liang, Xing, Wenbin, Huang, Qiang, Cao, Dan, Zhao, Xinjie, Wang, Wenzhao, Lu, Xin, Xu, Zhiliang, Wang, Hongyang, Xu, Guowang. Metabolomics Study of Stepwise Hepatocarcinogenesis From the Model Rats to Patients: Potential Biomarkers Effective for Small Hepatocellular Carcinoma Diagnosis. MOLECULAR & CELLULAR PROTEOMICS[J]. 2012, 第 7 作者11(2): http://dx.doi.org/10.1074/mcp.M111.010694.
[85] 许国旺, 林晓惠, 赵欣捷, 胡春秀, 陈世礼, 李佳, 吴泽明, 路鑫. Functional metabolomics:platform development and its new applications. THE 6TH SHANGHAI INTERNATIONAL SYMPOSIUM ON ANALYTICAL CHEMISTRY. 2012, 第 3 作者86, http://159.226.238.44/handle/321008/117058.
[86] 陈世礼, 戴伟东, 李勇, 赵欣捷, 尹沛源, 李佳, 路鑫, 许国旺. Discovery of potential biomarkers by using chromatography-mass spectrometry based metabolomics:how to conquer the effect of high concentrations of coexisting metabolites. 27TH INTERNATIONAL SYMPOSIUM ON MICROSCALE BIOSEPARATIONS AND ANALYSES. 2012, 第 4 作者24, http://159.226.238.44/handle/321008/117049.
[87] 林晓惠, 阮强, KangYan, 陈世礼, 赵欣捷. A Modified SVM Method for Analyzing Metabonomics Data from HPLC-MS. 36TH INTERNATIONAL SYMPOSIUM ON HIGH PERFORMANCE LIQUID PHASE SEPARATIONS AND RELATED TECHNIQUES. 2011, 第 5 作者287, http://159.226.238.44/handle/321008/117358.
[88] 许国旺, 陈静, 赵欣捷, 尹沛源, 王文昭, 路鑫. Metabolic biomarker discovery of complicated diseases by using LC-MS based metabonomics. 第五届上海国际分析化学研讨会文集. 2011, 第 3 作者1-1, http://159.226.238.44/handle/321008/115888.
[89] 许国旺, 赵欣捷, 胡春秀, 王晓琳, 陈世礼, 李佳. A functional metabolomics platform based on non-target and target chromatography-mass spectrometry. 2011 ANNUAL MEETING OF KSMS & 2ND AOMSC. 2011, 第 2 作者58-0, http://159.226.238.44/handle/321008/116059.
[90] 许国旺, 赵欣捷, 尹沛源, 胡春秀, 路鑫. DISEASE BIOMARKER DISCOVERY AND IDENTIFICATION BY USING MASS SPECTROMETRY BASED METABOLOMICS. 14TH BEIJING CONFERENCE AND EXHIBITION ON INSTRUMENTAL ANALYSIS. 2011, 第 2 作者425, http://159.226.238.44/handle/321008/117367.
[91] 王文昭, YexiongTan, YiHong, 尹沛源, LiangTang, 高鹏, MinWang, 黄强, 陈静, 李响, LiweiDong, 赵欣捷, ZhenzhenYao, 路鑫, 许国旺, HongyangWang. Bile acids as Novel Indicator of Hepatocellular Carcinoma: Small-Molecule Markers Screening from Bile Fluid to Serum. PROCEEDING OF HPLC 2011. 2011, 第 12 作者487-0, http://159.226.238.44/handle/321008/116070.
[92] 许国旺, 赵欣捷, 尹沛源, 黄强, 周丽娜, 路鑫. LC-MS based metabolomics for disease biomarker discovery and confirmation. 36TH INTERNATIONAL SYMPOSIUM ON HIGH PERFORMANCE LIQUID PHASE SEPARATIONS AND RELATED TECHNIQUES. 2011, 第 2 作者1, http://159.226.238.44/handle/321008/117361.
[93] 尹沛源, 赵欣捷, 路鑫, 许国旺. Methodology and applications of HPLC MS based metabolomics in the exploration of biomarkers. SINO-GERMAN FRONTIERS OF SCIENCE SYMPOSIUM 2011. 2011, 第 2 作者5, http://159.226.238.44/handle/321008/117368.
[94] 陈世礼, 尹沛源, 赵欣捷, WenbinXing, 胡春秀, 周丽娜, 许国旺. Serum lipid profiling of patients with chronic hepatitis B, cirrhosis and hepatocellular carcinoma by ultra fast liquid chromatography/ion trap-time of flight mass spectrometry. 37TH INTERNATIONAL SYMPOSIUM ON HIGH PERFORMANCE LIQUID PHASE SEPARATIONS AND RELATED TECHNIQUES. 2011, 第 3 作者721, http://159.226.238.44/handle/321008/117333.
[95] 李佳, 赵欣捷, 胡春秀, 陈世礼, 周丽娜, 许国旺. Qualitative and quantitative analysis of ceramide species in biological samples in an untargeted lipidomic profiling platform by high resolution LC-MS. PROCEEDING OF HPLC 2011. 2011, 第 2 作者498-0, http://159.226.238.44/handle/321008/116078.
[96] 李佳, 赵欣捷, 胡春秀, 陈世礼, 周丽娜, 许国旺. Qualitative and quantitative analysis of ceramide species in biological samples in an untargeted lipidomic profiling platform by high resolution LC-MS. 37TH INTERNATIONAL SYMPOSIUM ON HIGH PERFORMANCE LIQUID PHASE SEPARATIONS AND RELATED TECHNIQUES. 2011, 第 2 作者498, http://159.226.238.44/handle/321008/117336.
[97] 陈世礼, 尹沛源, 赵欣捷, WenbinXing, 胡春秀, 周丽娜, 许国旺. Serum lipid profiling of patients with chronic hepatitis B, cirrhosis and hepatocellular carcinoma by ultra fast liquid chromatography/ion trap-time of flight mass spectrometry. PROCEEDINGOFHPLC2011. 2011, 第 3 作者721-0, http://159.226.238.44/handle/321008/116081.
[98] 许国旺, 赵欣捷, 尹沛源, 胡春秀, 路鑫. DISEASE BIOMARKER DISCOVERY AND IDENTIFICATION BY USING MASS SPECTROMETRY BASED METABOLOMICS. PROCEEDING OF BCEIA 2011. 2011, 第 2 作者425-1, http://159.226.238.44/handle/321008/116047.
[99] 许国旺, 陈静, 赵欣捷, 尹沛源, 路鑫, 孔宏伟. Metabolic biomarker discovery and confirmation by using metabonomics. METABOLOMICS 2011. 2011, 第 3 作者1-0, http://159.226.238.44/handle/321008/116052.
[100] 许国旺, 陈静, 赵欣捷, 尹沛源, 路鑫, 孔宏伟. Metabolic biomarker discovery and confirmation by using metabonomics. 7TH INTERNATIONAL CONFERENCE OF THE METABOLOMICS SOCIETY. 2011, 第 3 作者1, http://159.226.238.44/handle/321008/117362.
[101] 王文昭, YexiongTan, YiHong, 尹沛源, LiangTang, 高鹏, MinWang, 黄强, 陈静, 李响, LiweiDong, 赵欣捷, ZhenzhenYao, 路鑫, 许国旺, HongyangWang. Bile acids as Novel Indicator of Hepatocellular Carcinoma: Small-Molecule Markers Screening from Bile Fluid to Serum. 37TH INTERNATIONAL SYMPOSIUM ON HIGH PERFORMANCE LIQUID PHASE SEPARATIONS AND RELATED TECHNIQUES. 2011, 第 12 作者487, http://159.226.238.44/handle/321008/117344.
[102] 赵欣捷, 陈继红, 石先哲, 许国旺. Metabolomic identification of potential biomarkers for acute graft rejection of renal transplantation by using RPLC and HILIC coupled with mass spectrometry. 37TH INTERNATIONAL SYMPOSIUM ON HIGH PERFORMANCE LIQUID PHASE SEPARATIONS AND RELATED TECHNIQUES. 2011, 第 1 作者485, http://159.226.238.44/handle/321008/117346.
[103] 赵欣捷, 陈继红, 石先哲, 许国旺. Metabolomic identification of potential biomarkers for acute graft rejection of renal transplantation by using RPLC and HILIC coupled with mass spectrometry. PROCEEDING OF HPLC 2011. 2011, 第 1 作者485-0, http://159.226.238.44/handle/321008/116068.
[104] 陈世礼, YanChu, 赵欣捷, 高鹏, LiZhang, LibinZhan, 许国旺. HPLC-MS-Based Metabonomics Reveals Disordered Lipid Metabolism in Patients with Metabolic Syndrome. PROGRAM AND ABSTRACTS OF 2011 INTERNATIONAL SYMPOSIUM ON ANALYTICAL SCIENCE & TECHNOLOGY. 2011, 第 3 作者169-4, http://159.226.238.44/handle/321008/116058.
[105] 陈世礼, YanChu, 赵欣捷, 高鹏, LiZhang, LibinZhan, 许国旺. HPLC-MS-Based Metabonomics Reveals Disordered Lipid Metabolism in Patients with Metabolic Syndrome. 2011 INTERNATIONAL SYMPOSIUM ON ANALYTICAL SCIENCE & TECHNOLOGY. 2011, 第 3 作者169, http://159.226.238.44/handle/321008/117356.
[106] 许国旺, 赵欣捷, 胡春秀, 王晓琳, 陈世礼, 李佳. A functional metabolomics platform based on non-target and target chromatography-mass spectrometry. THE 2ND ASIAN AND OCEANIC MASS SPECTROMETRY CONFERENCE. 2011, 第 2 作者58, http://159.226.238.44/handle/321008/117355.
[107] 许国旺, 赵欣捷, 尹沛源, 陈静, 路鑫. Comprehensive identification of metabolic biomarkers in HPLC MSbased. 58th annual conference on mass spectrometry,japan & 1st asian and oceanic mass spectrometry conference. 2010, 第 2 作者145/2, http://159.226.238.44/handle/321008/114440.
[108] 许国旺, 赵欣捷, 陈静, 尹沛源, 杨芹, 路鑫. Metabonomics method development based on a new online two-dimensional. Eleventh international symposium on hyphenated techniques in chromatography and hyphenated chromatographic analyzers. 2010, 第 2 作者kn16/2, http://159.226.238.44/handle/321008/114414.
[109] Wang, Wenzhao, Feng, Bo, Li, Xiang, Yin, Peiyuan, Gao, Peng, Zhao, Xinjie, Lu, Xin, Zheng, Minhua, Xu, Guowang. Urinary metabolic profiling of colorectal carcinoma based on online affinity solid phase extraction-high performance liquid chromatography and ultra performance liquid chromatography-mass spectrometry. MOLECULAR BIOSYSTEMS[J]. 2010, 第 6 作者6(10): 1947-1955, http://159.226.238.44/handle/321008/141631.
[110] Lehmann, Rainer, Zhao, Xinjie, Weigert, Cora, Simon, Perikles, Fehrenbach, Elvira, Fritsche, Jens, Machann, Juergen, Schick, Fritz, Wang, Jiangshan, Hoene, Miriam, Schleicher, Erwin D, Haering, HansUlrich, Xu, Guowang, Niess, Andreas M. Medium Chain Acylcarnitines Dominate the Metabolite Pattern in Humans under Moderate Intensity Exercise and Support Lipid Oxidation. PLOS ONE[J]. 2010, 第 2 作者5(7): http://159.226.238.44/handle/321008/142257.
[111] Hu, Chunxiu, Hoene, Miriam, Zhao, Xinjie, Haering, Hans U, Schleicher, Erwin, Lehmann, Rainer, Han, Xianlin, Xu, Guowang, Weigert, Cora. Lipidomics Analysis Reveals Efficient Storage of Hepatic Triacylglycerides Enriched in Unsaturated Fatty Acids after One Bout of Exercise in Mice. PLOS ONE[J]. 2010, 第 3 作者5(10): http://dx.doi.org/10.1371/journal.pone.0013318.
[112] Lucio, Marianna, Fekete, Agnes, Weigert, Cora, Waegele, Brigitte, Zhao, Xinjie, Chen, Jing, Fritsche, Andreas, Haering, HansUlrich, Schleicher, Erwin D, Xu, Guowang, SchmittKopplin, Philippe, Lehmann, Rainer. Insulin Sensitivity Is Reflected by Characteristic Metabolic Fingerprints - A Fourier Transform Mass Spectrometric Non-Targeted Metabolomics Approach. PLOS ONE[J]. 2010, 第 5 作者5(10): https://doaj.org/article/7c7a9502758244dba8547eb94b311ac0.
[113] LehmannR, 赵欣捷, WeigertC, SimonP, FehrenbachE, HoeneM, SchleicherED, HaringHU, 许国旺, NiessAM. Functional metabolomics-Identification and characterization of biomarkers detected under moderate intensity exercise conditions. the metabolomics conference 2010. 2010, 第 2 作者116/2, http://159.226.238.44/handle/321008/114444.
[114] 许国旺, 赵欣捷, 陈静, 尹沛源, 杨芹, 路鑫. 基于一种新的在线二维HILIC /反相高效液相色谱法分离系统的代谢组学方. eleventh international symposium on hyphenated techniques in chromatography and hyphenated chromatographic analyzers. 2010, 第 2 作者kn16/2, http://159.226.238.44/handle/321008/114414.
[115] 许国旺, 陈静, 赵欣捷, 尹沛源, 王文昭, 路鑫. Metabolic biomarker discovery of complicated diseases by using LC-MS based metabonomics. ANALYTICA CHINA CONFERENCE 2010. 2010, 第 3 作者1, http://159.226.238.44/handle/321008/117519.
[116] Zhao, Xinjie, Fritsche, Jens, Wang, Jiangshan, Chen, Jing, Rittig, Kilian, SchmittKopplin, Philippe, Fritsche, Andreas, Haering, HansUlrich, Schleicher, Erwin D, Xu, Guowang, Lehmann, Rainer. Metabonomic fingerprints of fasting plasma and spot urine reveal human pre-diabetic metabolic traits. METABOLOMICS[J]. 2010, 第 1 作者6(3): 362-374, http://dx.doi.org/10.1007/s11306-010-0203-1.
[117] 许国旺, 尹沛源, 赵欣捷, 陈世礼, 路鑫, EDSchleicher, RLehmann. LC-MS based Metabonomics: Effect of Preanalytical Procedures. 35th international symposium on high performance liquid phase separations & related techniques. 2010, 第 3 作者23/2, http://159.226.238.44/handle/321008/114420.
[118] 许国旺, 赵欣捷, 尹沛源, 陈静, 路鑫. 基于液质联用的代谢组学中代谢标志物的全面鉴定. 58th annual conference on mass spectrometry,japan & 1st asian and oceanic mass spectrometry conference. 2010, 第 2 作者145/2, http://159.226.238.44/handle/321008/114440.
[119] 许国旺, 石先哲, 杨芹, 赵素敏, 单圆鸿, 赵欣捷. LC-MS based metabonomics: separation window extending from either hydrophilic or hydrophobic metabolites to global metabolites. 2010 international chemical congress of pacific basin societies. 2010, 第 6 作者62/2, http://159.226.238.44/handle/321008/114416.
[120] 许国旺, 石先哲, 杨芹, 赵素敏, 单圆鸿, 赵欣捷. 基于液质联用的代谢组学:从分离亲水或疏水性代谢物扩展到整体代谢物的分离. 2010 international chemical congress of pacific basin societies. 2010, 第 6 作者62/2, http://159.226.238.44/handle/321008/114416.
[121] 许国旺, 尹沛源, 赵欣捷, 王文昭, 陈静, 路鑫. Applications of Metabonomics in Diagnosing Disease and Predicting the Disease. the 34th international symposium on high performance. 2009, 第 3 作者54/1, http://159.226.238.44/handle/321008/113722.
[122] 许国旺, 陈静, 赵欣捷, 尹沛源, 杨芹, 路鑫. Comparison of one-dimensional and two-dimensional LC-MS methods for metabonomics. the 13th beijing conference and exhibition on instrumental analysis. 2009, 第 3 作者398/2, http://159.226.238.44/handle/321008/113724.
[123] 陈静, 单圆鸿, 严沁, 赵素敏, 尹沛源, 赵欣捷, 路鑫, 席晓薇, 万小平, 许国旺. 一种基于液相色谱-质谱技术进行血清代谢组学研究的方法:从代谢指纹到潜在标志物. 中国科学:B辑[J]. 2009, 第 6 作者1268-1276, http://lib.cqvip.com/Qikan/Article/Detail?id=31933307.
[124] 许国旺, 赵欣捷, 陈静, 杨芹, 尹沛源, 高鹏, 孔宏伟, 路鑫. Development of LC-MS based method for metabonomics. 24th international symposium on microscale bioseparations. 2009, 第 2 作者91/1, http://159.226.238.44/handle/321008/113714.
[125] Yin, Peiyuan, Wan, Dafang, Zhao, Chunxia, Chen, Jing, Zhao, Xinjie, Wang, Wenzhao, Lu, Xin, Yang, Shengli, Gu, Jianren, Xu, Guowang. A metabonomic study of hepatitis B-induced liver cirrhosis and hepatocellular carcinoma by using RP-LC and HILIC coupled with mass spectrometry. MOLECULAR BIOSYSTEMS[J]. 2009, 第 5 作者5(8): 868-876, http://159.226.238.44/handle/321008/102163.
[126] 汪江山, 孔宏伟, 路鑫, 赵欣捷, 许国旺. 代谢组学中的分离分析科学. 化学进展[J]. 2009, 第 4 作者21(11): 2388-2396, http://lib.cqvip.com/Qikan/Article/Detail?id=32154718.
[127] Chen, Jing, Wang, Wenzhao, Lv, Shen, Yin, Peiyuan, Zhao, Xinjie, Lu, Xin, Zhang, Fengxia, Xu, Guowang. Metabonomics study of liver cancer based on ultra performance liquid chromatography coupled to mass spectrometry with HILIC and RPLC separations. ANALYTICA CHIMICA ACTA[J]. 2009, 第 5 作者650(1): 3-9, http://dx.doi.org/10.1016/j.aca.2009.03.039.
[128] Wang Jiangshan, Kong Hongwei, Lu Xin, Zhao Xinjie, Xu Guowang. Separation Science in the Context of Metabonomics: Current Platforms and Future Trends. PROGRESS IN CHEMISTRY[J]. 2009, 第 4 作者21(11): 2388-2396, http://159.226.238.44/handle/321008/141610.
[129] 赵素敏, 尹沛源, 赵欣捷, 路鑫, 席晓薇, 万小平, 许国旺, 陈静, 单圆鸿, 严沁. 一种基于液相色谱-质谱技术进行血清代谢组学研究的方法:从代谢指纹到潜在标志物. 中国科学:B辑[J]. 2009, 第 3 作者1268-1276, http://lib.cqvip.com/Qikan/Article/Detail?id=31933307.
[130] 汪江山, 赵欣捷, 尹沛源, 孔宏伟, 许国旺, 吕爱平. 类风湿性关节炎疾病分型的血浆代谢组学研究. 世界科学技术一中医药现代化[J]. 2009, 第 2 作者11(1): 201-205, http://159.226.238.44/handle/321008/102203.
[131] 汪江山, 赵欣捷, 尹沛源, 孔宏伟, 许国旺, 吕爱平. 类风湿性关节炎疾病分型的血浆代谢组学研究. 世界科学技术:中医药现代化[J]. 2009, 第 2 作者201-205, http://lib.cqvip.com/Qikan/Article/Detail?id=30068241.
[132] Zhao, Xinjie, Peter, Andreas, Fritsche, Jens, Elcnerova, Michaela, Fritsche, Andreas, Haering, HansUlrich, Schleicher, Erwin D, Xu, Guowang, Lehmann, Rainer. Changes of the plasma metabolome during an oral glucose tolerance test: is there more than glucose to look at?. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM[J]. 2009, 第 1 作者296(2): E384-E393, http://dx.doi.org/10.1152/ajpendo.90748.2008.
[133] 陈静, 单圆鸿, 严沁, 赵素敏, 尹沛源, 赵欣捷, 路鑫, 席晓薇, 万小平, 许国旺. 一种基于液相色谱-质谱技术进行血清代谢组学研究的方法: 从代谢指纹到潜在标志物. 中国科学 B[J]. 2009, 第 6 作者39(10): 1268-1276, http://159.226.238.44/handle/321008/102739.
[134] 许国旺, 王媛, 赵欣捷, 路鑫, 杨芹, 汪江山. TOWARD THE ''COMPREHENSIVE'' ANALYSIS OF SMALL MOLECULES IN BIOFLUIDS AND NATURAL PRODUCTS BASED ON LC-MSN. 32nd international symposium & exhibit on high performance liquid phase separations and related techniques. 2008, 第 3 作者21/1, http://159.226.238.44/handle/321008/112956.
[135] Lu, Xin, Zhao, Xinjie, Bai, Changmin, Zhao, Chunxia, Lu, Guo, Xu, Guomang. LC-MS-based metabonomics analysis. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES[J]. 2008, 第 2 作者866(1-2): 64-76, http://dx.doi.org/10.1016/j.jchromb.2007.10.022.
[136] Yin, Peiyuan, Mohemaiti, Patamu, Chen, Jing, Zhao, Xinjie, Lu, Xin, Yimiti, Adilijiang, Upur, Halmurat, Xu, Guowang. Serum metabolic profiling of abnormal savda by liquid chromatography/mass spectrometry. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES[J]. 2008, 第 4 作者871(2): 322-327, http://dx.doi.org/10.1016/j.jchromb.2008.05.043.
[137] Chen, Jing, Zhao, Xinjie, Fritsche, Jens, Yin, Peiyuan, SchmittKopplin, Philippe, Wang, Wenzhao, Lu, Xin, Haring, Hans Ulrich, Schleicher, Erwin D, Lehmann, Rainer, Xu, Guowang. Practical approach for the identification and isomer elucidation of biomarkers detected in a metabonomic study for the discovery of individuals at risk for diabetes by integrating the chromatographic and mass spectrometric information. ANALYTICAL CHEMISTRY[J]. 2008, 第 2 作者80(4): 1280-1289, http://159.226.238.44/handle/321008/100423.
[138] Xu, Guowang, Wang, Yuan, Zhao, Xinjie, Chen, Jing, Yin, Peiyuan, Lu, Xin. A new two-dimensional LC-MS/MS-based metabonomics method and its applications in the traditional Chinese medicines and diseases. JOURNAL OF BIOTECHNOLOGY[J]. 2008, 第 3 作者136: S26-S26, http://dx.doi.org/10.1016/j.jbiotec.2008.07.046.
[139] 王媛, 汪江山, Ming Yao, 赵欣捷, Jens Fritsche, Philippe SchmittKopplin, Zongwei Cai, 万大方, 路鑫, 杨胜利, 顾健人, Hans Ulrich Hauml, ring, Erwin D Schleicher, Rainer Lehmann, 许国旺. Metabonomics Study on the Effects of the Ginsenoside Rg3 in a β-Cyclodextrin-Based Formulation on Tumor-Bearing Rats by a Fully Automatic Hydrophilic Interaction/Reversed-Phase Column-Switching HPLC−ESI-MS Approach. ANALYTICAL CHEMISTRY[J]. 2008, 第 4 作者80: 4680-4688, http://159.226.238.44/handle/321008/100445.
[140] Lu, Xin, Zhao, Xinjie, Bai, Changmin, Zhao, Chunxia, Lu, Guo, Xu, Guowang. LC-MS-based metabonomics analysis (vol 866, pg 64, 2008). JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2008, 第 2 作者874(1-2): 125-125, http://159.226.238.44/handle/321008/141154.
[141] 许国旺, 赵欣捷, 王媛, 尹沛源, 陈静, JensFritsche, 路鑫, HansUlrichHauml, ring, ErwinDSchleicher, PhilippeSchmittKopplin, RainerLehmann. What LC-MS methods do we need for metabonomics analysis?. 33th international symposium on high performance liquid separations and related techniques. 2008, 第 2 作者136/1, http://159.226.238.44/handle/321008/113090.
[142] Xu, Guowang, Wang, Yuan, Zhao, Xinjie, Chen, Jing, Yin, Peiyuan, Lu, Xin. A new two-dimensional LC-MS/MS-based metabonomics method and its applications in the traditional Chinese medicines and diseases. JOURNAL OF BIOTECHNOLOGY[J]. 2008, 第 3 作者136: S26-S26, http://dx.doi.org/10.1016/j.jbiotec.2008.07.046.
[143] Wang, Yuan, Lehmann, Rainer, Lu, Xin, Zhao, Xinjie, Xu, Guowang. Novel, fully automatic hydrophilic interaction/reversed-phase column-switching high-performance liquid chromatographic system for the complementary analysis of polar and apolar compounds in complex samples. JOURNAL OF CHROMATOGRAPHY A[J]. 2008, 第 4 作者1204(1): 28-34, http://dx.doi.org/10.1016/j.chroma.2008.07.010.
[144] 许国旺, 王媛, RaierLehmann, 赵欣捷, 陈静, 尹沛源, PhilippeSchmittKopplin, 路鑫, HansUlrichHauml, ring, ErwinDSchleicher. LC-MS/MS Metabonomics Method Development Based on a Novel Two-Dimensional Liquid Chromatographic System and an Integrated Identification Strategy of Potential Biomarkers. the 22nd international symposium on microscale bioseparations and methods for systems biology. 2008, 第 4 作者30/1, http://159.226.238.44/handle/321008/112954.
[145] 尹沛源, Patamu Mohemaiti, 陈静, 赵欣捷, 路鑫, Adilijiang Yimiti, Halmurat Upur, 许国旺. Serum metabolic profiling of abnormal savda by liquid chromatography / mass spectrometry. JOURNAL OF CHROMATOGRAPHY B[J]. 2008, 第 4 作者871(2): 322-327, http://dx.doi.org/10.1016/j.jchromb.2008.05.043.
[146] Wang, Yuan, Wang, Jiangshan, Yao, Ming, Zhao, Xinjie, Fritsche, Jens, SchmittKopplin, Philippe, Cai, Zongwei, Wan, Dafang, Lu, Xin, Yang, Shengli, Gu, Jianren, Haering, Hans Ulrich, Schleicher, Erwin D, Lehmann, Rainer, Xu, Guowang. Metabonomics study on the effects of the ginsenoside Rg3 in a beta-cyclodextrin-based formulation on tumor-bearing rats by a fully automatic hydrophilic interaction/reversed-phase column-switching HPLC-ESI-MS approach. ANALYTICAL CHEMISTRY[J]. 2008, 第 4 作者80(12): 4680-4688, https://www.webofscience.com/wos/woscc/full-record/WOS:000256763400031.
[147] 许国旺, 赵欣捷, 尹沛源, 王媛, 陈静, 路鑫. Biomarker discovery and identification in chromatography-MSn-based Metabonomics. dalian international symposia and exhibition on chromatography. 2007, 第 2 作者44/1, http://159.226.238.44/handle/321008/112538.
[148] 赵欣捷, RainerLehmann, 汪江山, ErwinDSchleicher, PhSchmittKopplin, 许国旺. Metabonomics study on identifying insulin resistant individuals by UPLC-Q TOF MS. dalian international symposia and exhibition on chromatography. 2007, 第 1 作者223/2, http://159.226.238.44/handle/321008/112544.
[149] 王文昭, 赵欣捷, 李响, 陈静, 李方楼, 许国旺. 尿中修饰核苷代谢轮廓分析在肺癌诊断中的作用. 中国医学科学院学报[J]. 2007, 第 2 作者29(6): 738-741, http://lib.cqvip.com/Qikan/Article/Detail?id=26557267.
[150] 许国旺, 赵欣捷, 尹沛源, LehmannRainer, 王媛, 陈静, 路鑫, Hauml, ringHansUlrich, SchleicherErwinD. Biomarker discovery and identification in LC/MSn for Metabonomics. 31st international symposium on high performance liquid phase separations and related techniques. 2007, 第 2 作者74/1, http://159.226.238.44/handle/321008/112590.
[151] 田晶, 李丹, 赵欣捷, 徐龙权, 许国旺. separation and identification of soybean soponins by UPLC/TOF-MS. dalian international symposia and exhibition on chromatography. 2007, 第 3 作者87/1, http://159.226.238.44/handle/321008/112548.
[152] 李方楼, 赵欣捷, 许国旺. 硅胶基硝化苯硼酸亲和色谱材料的合成及应用. 分析化学[J]. 2006, 第 2 作者34(10): 1366-1370, http://www.irgrid.ac.cn/handle/1471x/235995.
[153] 卢果, 许国旺, 路鑫, 赵欣捷, 汪江山, 杨军, 王畅, 孔宏伟. DETERMINATION OF GENDER DIFFERENCE BASED ON METABOLITES IN URINE BY USING UPLC/TOF-MS. 30th international symposium on high performance liquid phase separations and related techniques. 2006, 第 4 作者65/1, http://159.226.238.44/handle/321008/112172.
[154] 赵欣捷, 汪江山, 郑育芳, 孔宏伟, 蔡宗苇, 许国旺. Metabolite Fingerprint and Biomarkers Identification of Rat Urine after Dosed with Ginsenoside Rg3 Based on UPLC/TOF-MSn. the 29th international symposium on capillary chromatography and the 3rd gc×gc symposium. 2006, 第 1 作者o.17/2, http://159.226.238.44/handle/321008/112218.
[155] 许国旺, 杨军, 王畅, 孔宏伟, 赵欣捷, 袁凯龙, 汪江山, 路鑫. METABONOMICS APPLICATIONS IN DISEASE BIOMARKER DISCOVERY AND SAFETY AND EFFICACY ASSESSMENTS OF TRADITIONAL CHINESE MEDICINES BASED ON GC×GC-TOF MS AND UPLC-Q-TOF MSn. ninth international symposium on hyphenated techniques in chromatography and hyphenated chromatographic analyzers. 2006, 第 5 作者41.2-1/2, http://159.226.238.44/handle/321008/112168.
[156] 卢果, 汪江山, 赵欣捷, 孔宏伟, 许国旺. study on gender difference based on metabolites in urine by Ultra High Performance Liquid Chromatography/Time of Flight Mass Spectrometry. 色谱[J]. 2006, 第 3 作者24(2): 109-113, http://159.226.238.44/handle/321008/97589.
[157] 许国旺, 杨军, 尹沛源, 赵欣捷, 路鑫. Data analysis and biomarker identification method development in LC/MSn for Metabonomics. dicp symposium (xi) on analytical biochemistry and traditional chinese medicine metabonomics. 2006, 第 4 作者4/2, http://159.226.238.44/handle/321008/112252.
[158] 许国旺, 路鑫, 赵欣捷, 汪江山, 杨军, 王畅, 孔宏伟, 袁凯龙, 石先哲, 赵素敏. HIGH RESOLUTION ANALYSIS OF SMALL BIOMOLECULES BY CHROMATOGRAPHY HYPHENATED WITH MASS SPECTROMETRY. 30th international symposium on high performance liquid phase separations and related techniques. 2006, 第 3 作者12/1, http://159.226.238.44/handle/321008/112170.
[159] 许国旺, 路鑫, 赵欣捷, 王媛, 尹沛源, 杨军, 石先哲, 赵素敏, 王文昭, 马晨菲, 袁凯龙, 李方楼. Chromatography-MS spectrometry Technique for Metabonomics: Challenge and Strategy. the 4th international symposium on worldwide chinese scholars on analytical chemistry. 2006, 第 3 作者57/1, http://159.226.238.44/handle/321008/112228.
[160] Zhao, Xinjie, Wang, Wenzhao, Wang, Jiangshan, Yang, Jun, Xu, Guowang. Urinary profiling investigation of metabollites with cis-diol structure from cancer patients based on UPLC-MS and HPLC-MS as well as multivariate statistical analysis. JOURNAL OF SEPARATION SCIENCE[J]. 2006, 第 1 作者29(16): 2444-2451, http://159.226.238.44/handle/321008/140304.
[161] 汪江山, 赵欣捷, 郑育芳, 孔宏伟, 卢果, 蔡宗苇, 许国旺. 超高效液相色谱/飞行时间质谱用于人参皂甙Rg3作用后大鼠尿液代谢物指纹图谱分析及标记物的鉴定. 色谱[J]. 2006, 第 2 作者24(1): 5-9, http://lib.cqvip.com/Qikan/Article/Detail?id=21079109.
[162] 卢果, 汪江山, 赵欣捷, 孔宏伟, 许国旺. 超高效液相色谱/飞行时间质谱法分析尿液中的代谢物用于区分人类性别的研究. 色谱[J]. 2006, 第 3 作者24(2): 109-113, http://lib.cqvip.com/Qikan/Article/Detail?id=21460355.
[163] 许国旺, 赵欣捷, 王媛, 尹沛源, 杨军, 孔宏伟, 汪江山, 石先哲, 赵素敏, 王文昭. LC/MS and LCxLC/MS-Based Metabonomics: Method Development and Applications. 23rd lc/ms montreux symposium. 2006, 第 2 作者16/1, http://159.226.238.44/handle/321008/112194.
[164] Li Fanglou, Zhao Xinjie, Xu Guowang. Synthesis and application of a nitroboronic acid-substituated silica for affinity chromatography. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY[J]. 2006, 第 2 作者34(10): 1366-1370, http://159.226.238.44/handle/321008/140211.
[165] Li, Fanglou, Zhao, Xinjie, Wang, Wenzhao, Xu, Guowang. Synthesis of silica-based benzeneboronic acid affinity materials and application as pre-column in coupled-column high-performance liquid chromatography. ANALYTICA CHIMICA ACTA[J]. 2006, 第 2 作者580(2): 181-187, http://dx.doi.org/10.1016/j.aca.2006.07.058.
[166] 许国旺, 赵欣捷, 袁凯龙, 汪江山, 杨军, 王畅, 孔宏伟, 路鑫. Metabonomics: Challenge to Analytical Techniques and Its Applications in Disease Biomarker Discovery and Drug Investigation. 3rd shanghai international symposium on analytical chemistry. 2006, 第 2 作者56/1, http://159.226.238.44/handle/321008/112230.
[167] 赵欣捷, 王文昭, 汪江山, 杨军, 许国旺. Urinary profiling investigation of metabolites with cis-diol structure from cancer patients based on UPLC-MS and HPLC-MS as well as multivariate statistical analysis. JOURNAL OF SEPARATION SCIENCE[J]. 2006, 第 1 作者29: 2444-2451, http://159.226.238.44/handle/321008/97597.
[168] ErwinDSchleicher, RainerLehmann, HansUlrichHauml, ring, 赵欣捷, 汪江山, 许国旺. Identification of insulin resistant individuals by metabonomic analysis of spot urine – A new approach for a present analytical problem. DICP Symposium (XI) on Analytical Biochemistry and Traditional Chinese Medicine Metabonomics. 2006, 第 5 作者10/2, http://159.226.238.44/handle/321008/112254.
[169] 许国旺, 汪江山, 杨军, 王畅, 赵欣捷, 袁凯龙. 第33章代谢组学及其方法. 《生命分析化学》 ISBN 7-03-016789-9[J]. 2006, 第 5 作者868-903, http://159.226.238.44/handle/321008/98123.
[170] 田晶, 路鑫, 杨军, 孔宏伟, 王媛, 赵欣捷, 唐平, 苑广志, 许国旺. 生物制药研究中的多维色谱. 色谱[J]. 2005, 第 6 作者23(1): 32-36, http://lib.cqvip.com/Qikan/Article/Detail?id=11699524.
[171] 许国旺, 路鑫, 孔宏伟, 石先哲, 赵欣捷, 田晶, 卢果. 色谱专家系统的应用和发展. 色谱[J]. 2005, 第 5 作者23(5): 449-455, http://lib.cqvip.com/Qikan/Article/Detail?id=20220639.
[172] 赵欣捷, 郑育芳, 张普敦, 孔宏伟, 许国旺. 整体柱高效液相色谱法测定尿中核苷的方法研究. 色谱[J]. 2005, 第 1 作者23(1): 73-75, http://lib.cqvip.com/Qikan/Article/Detail?id=11699533.
[173] Zheng, YuFang, Yang, Jun, Zhao, XinJie, Feng, Bo, Kong, HongWei, Chen, YingJie, Lv, Shen, Zheng, MinHua, Xu, GuoWang. Urinary nucleosides as biological markers for patients with colorectal cancer. WORLD JOURNAL OF GASTROENTEROLOGY[J]. 2005, 第 3 作者11(25): 3871-3876, http://lib.cqvip.com/Qikan/Article/Detail?id=16078123.
[174] 许国旺, 杨军, 郑育芳, 孔宏伟, 赵欣捷, 杨青. 基于色谱技术的代谢组学技术平台的建立. international symposium advances and applications of chromatography in industry. 2004, 第 5 作者1/4, http://159.226.238.44/handle/321008/111620.
[175] 许国旺, 杨军, 郑育芳, 孔宏伟, 赵欣捷, 杨青. Establishment of A Technique Platform of Chromatography-based Metabonomics. International symposium advances and applications of chromatography in industry. 2004, 第 5 作者1/4, http://159.226.238.44/handle/321008/111620.
[176] 赵春霞, 明平文, 杨凌, 刘中民, 张卓然, 马磊, 许磊, 齐越, 孙承林, 韩秀文, 陈严, 曲振平, 缪少军, 郑丛龙, 赵欣捷, 杜逊甫, 刘波, 孔宏伟, 王畅, 叶芬, 刘守新, 胡刚, 刘页, 张涛, 黄向阳, 包信和, 许国旺. 催化材料对病毒吸附及灭活作用特性的研究. 色谱[J]. 2003, 第 15 作者21(3): 222-225, http://lib.cqvip.com/Qikan/Article/Detail?id=7902613.
[177] 路鑫, 吴浩, 许国旺, 管爱民, 赵欣捷, 宋怡静, 张桐凤, 刘斌. 在线分析己烷中痕量四氢呋喃的气相色谱柱系统研究. 色谱[J]. 2001, 第 5 作者19(3): 196-199, http://lib.cqvip.com/Qikan/Article/Detail?id=5343453.
[178] 许国旺, 叶芬, 孔宏伟, 路鑫, 赵欣捷. 全二维气相色谱技术及其进展. 色谱[J]. 2001, 第 5 作者19(2): 132-136, http://lib.cqvip.com/Qikan/Article/Detail?id=5073308.
[179] 许国旺, 赵欣捷, 叶芬, 路鑫. 固相微萃取/气相色谱/质谱联用测定水中的2,4—二硝基苯酚. 色谱[J]. 1999, 第 2 作者17(2): 131, http://lib.cqvip.com/Qikan/Article/Detail?id=3487376.

科研活动

   
科研项目
( 1 ) 中德合作发展全脂及代谢组学平台用新代谢生物标志物的鉴定及其功能表征, 参与, 国家任务, 2012-01--2015-12
( 2 ) 代谢小分子标志物筛选鉴定和应用, 参与, 国家任务, 2012-01--2015-12
( 3 ) 大规模非靶向LC-MS代谢组学分析新策略研究, 负责人, 国家任务, 2020-01--2023-12
( 4 ) 基于LC-MSn的代谢物定性策略研究, 负责人, 国家任务, 2016-01--2019-12
( 5 ) 基于微尺度多维LC-MS大数据和人工智能的临床代谢组学新技术研究, 负责人, 国家任务, 2023-01--2026-12