Associate Professor

Centre for Translational Medicine R&D, Institute of Biomedical and Health Engineering

Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences

Address: 1068 Xueyuan Avenue, Shenzhen University Town, Shenzhen, China
Zipcode: 518055

Research Areas

Nanomaterials for Biomedical Applications

Nanomedicine (Cancer and Orthopaedic Diseases)

3D Printing Technology for Biomaterials


2009/Sep-2015/Jun, Department of Chemistry, Sun Yat-Sen University, Ph.D in Bioinorganic Chemistry, Advisor: Prof. Zong-Wan Mao

2005/Sep-2009/Jun, Department of Chemistry, Sun Yat-Sen University, Bachelor in Applied Chemistry


Work Experience

2019/May-Now, Associate Professor, Institute of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences

2017/Jun-2019/May, Research Fellow, Department of Chemical and Biomolecular Engineering, National University of Singapore, Advisor: Prof. Kyle Phua

2015/Jun- 2017/May, Postdoctoral Fellow, National Center for Nanoscience and Technology of ChinaAdvisor: Prof. Xing-Jie Liang



Representative Publications (* Corresponding,#Co-first author)

  1. Yuanchi Zhang, Cairong Li, Wei Zhang*, Junjie Deng, Yangyi Nie, Xiangfu Du, Ling Qin, Yuxiao Lai*,       3D-printed NIR-responsive shape memory polyurethane/magnesium scaffolds with tight-contact for robust bone regeneration. Bioactive Materials 2022, (IF=14.593)

  2.  Wei Zhang, Xiang-Fu Du, Ben Liu, Cairong Li, Jing Long, Mei-Xia Zhao*, Zhenyu Yao, Xing-Jie Liang*, Yuxiao Lai*, Engineering Supramolecular Nanomedicine for Targeted Near Infrared-triggered Mitochondrial Dysfunction to Potentiate Cisplatin for Efficient Chemophototherapy. ACS Nano 2022, 16, 1, 1421-1435. (IF=15.881)

  3. Ben Liu, Jing Long, Meng Zhang, Kaiming Cheng, Xin Gao, Yibo Zhou, Yi Li*, Zilong Tang*, Wei Zhang*, Mitochondria-targeted phosphorescent cyclometalated iridium (III) complex for bioimaging of H2S. Journal of Inorganic Biochemistry 2022, 226, 111626. (IF=4.155)

  4. Jing Long#, Wei Zhang#, Yingqi Chen, Bin Teng, Ben Liu, Huilin Li, Zhenyu Yao, Dou Wang, Long Li, Xue-Feng Yu, Ling Qin, Yuxiao Lai*, Multifunctional Magnesium Incorporated Scaffolds by 3D-Printing for Comprehensive Postsurgical Management of Osteosarcoma. Biomaterials 2021, 275, 120950. (Co-first author, IF=12.479)

  5. ​Xiang-Fu Du, Yi Li, Jing Long, Wei Zhang*, Dou Wang, Cai-Rong Li, Mei-Xia Zhao*, Yuxiao Lai*, Fabrication of cisplatin-loaded polydopamine nanoparticles via supramolecular self-assembly for photoacoustic imaging guided chemo-photothermal cancer therapy. Applied Materials Today 2021, 23, 101019. (IF=10.041)

  6. Wei Zhang, Yi Liu, Jas Min Chin, Kyle KL Phua*, Sustained release of PKR inhibitor C16 from mesoporous silica nanoparticles significantly enhances mRNA translation and anti-tumor vaccination. European Journal of Pharmaceutics and Biopharmaceutics 2021, 163, 179-187. (IF=5.571)

  7. Wei Zhang, Yi Li, Lanju Xu, Dou Wang, Jing Long, Meng Zhang, Yufei Wang, Yuxiao Lai*, Xing-Jie Liang*, Near-Infrared-Absorbing Conjugated Polymer Nanoparticles Loaded with Doxorubicin for Combinatorial Photothermal-Chemotherapy of Cancer. ACS Applied Polymer Materials 2020, 2, 4180-4187. (IF=4.089)

  8. Wei Zhang, Yan Wen, Dong-Xuan He, Yi-Feng Wang, Xiao-Li Liu, Chan Li, Xing-JieLiang*, Near-infrared AIEgens as transformers to enhance tumor treatment efficacy with controllable self-assembled redox-responsive carrier-free nanodrugs. Biomaterials 2019, 193, 12-21. (IF=12.479)

  9. Jianliang Shen#, Wei Zhang#, Ruogu Qi, Zong-Wan Mao*, Haifa Shen*, Engineering functional inorganic–organic hybrid systems: advances in siRNA therapeutics. Chemical Society Reviews 2018, 47, 1969-1995. (Co-first author, Front Cover, IF=54.564)

  10. Jing-Hua Sun#, Wei Zhang*, Dong-Yang Zhang, Jianliang Shen, Cai-Ping Tan, Liang-Nian Ji, Zong-Wan Mao*, Multifunctional mesoporous silica nanoparticles as efficient transporters of doxorubicin and chlorine e6 for chemo-photodynamic combinatorial cancer therapy. Journal of Biomaterials Applications 2018, 32, 1253-1264. (IF=2.442)

  11. Yan Wen, Wei Zhang*, Ningqiang Gong, Yi-Feng Wang, Hong-Bo Guo, Weisheng Guo, Paul C Wang, Xing-Jie Liang*, Carrier-free, self-assembled pure drug nanorods composed of 10-hydroxycamptothecin and chlorin e6 for combinatorial chemo-photodynamic antitumor therapy in vivo. Nanoscale, 2017, 9, 14347-14356. (IF=7.79)

  12. Wei Zhang, Jianliang Shen, Hua Su, Ge Mu, Jing-Hua Sun, Cai-Ping Tan, Xing-Jie Liang*, Liang-Nian Ji, Zong-Wan Mao*, Co-Delivery of Cisplatin Prodrug and Chlorin e6 by Mesoporous Silica Nanoparticles for Chemo-Photodynamic Combination Therapy to Combat Drug Resistance. ACS Applied Materials & Interfaces 2016, 8, 13332-13340. (IF=9.229)

  13. Dongxuan He#, Wei Zhang#, Hongzhang Deng, Shuaidong Huo, Yi-Feng Wang, Ningqiang Gong, Liangdong Deng, Xing-Jie Liang*, Anjie Dong*, Self-assembling Nanowires of an Amphiphilic Camptothecin Prodrug Derived from Homologous Derivative Conjugation. Chemical Communications 2016, 52, 14145-14148. (Co-first author, IF=6.222)

  14. Wei Zhang, Yi Li, Jing-Hua Sun, Cai-Ping Tan, Liang-Nian Ji, Zong-Wan Mao*, Supramolecular Self-assembled Nanoparticles for Chemo-Photodynamic Dual Therapy against Cisplatin Resistant Cancer Cells. Chemical Communications 2015, 51, 1807-1810. (Back Cover, IF=6.222)