071007-遗传学

鱼类免疫育种

2013-08--2019-05   美国伊利诺伊大学厄巴纳-香槟分校   博士
2010-08--2013-05   中国科学院水生生物研究所   硕士
2006-08--2010-05   武汉理工大学   理学学士

   

2026-06~现在, 中国科学院水生生物研究所, 研究员
2019-09~2026-05,美国贝勒医学院, 博士后

   

（1） Inflammation-and resolution-programmed myeloid circuits govern therapeutic resistance in epithelial and mesenchymal triple-negative breast cancer, The Journal of Clinical Investigation, 2026, 第 1 作者
（2） Unbiased niche labeling maps immune-excluded niche in bone metastasis, Cell, 2026, 
（3） Engineering Tregs-mediated immune tolerance via foxp3a overexpression to evade allograft transplantation barriers in zebrafish, Journal of Genetics and Genomics, 2026, 
（4） Heterotypic tumor microenvironments mirror dynamic wound-healing process, Trends in Cancer, 2026, 第 1 作者  通讯作者
（5） Tumor-derived arachidonic acid reprograms neutrophils to promote immune suppression and therapy resistance in triple-negative breast cancer, Immunity, 2025, 第 1 作者
（6） Single-cell profiling of bone metastasis ecosystems from multiple cancer types reveals convergent and divergent mechanisms of bone colonization, Cell Genomics, 2025, 
（7） Solid tumour-induced systemic immunosuppression involves dichotomous myeloid–B cell interactions, Nature cell biology, 2024, 
（8） Siglec-15/sialic acid axis as a central glyco-immune checkpoint in breast cancer bone metastasis, Proceedings of the National Academy of Sciences, 2024, 
（9） Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal, Cell Stem Cell, 2023, 
（10） Bone Metastasis Initiation Is Coupled with Bone Remodeling through Osteogenic Differentiation of NG2+ Cells, Cancer discovery, 2023, 
（11） The bone microenvironment invigorates metastatic seeds for further dissemination, Cell, 2021, 

   

（ 1 ） 鱼类借腹生殖育种生物学, 负责人, 中国科学院计划, 2026-06--2029-06
（ 2 ） Modulation of Epigenetic Target in the Bone to Treat Breast Cancer Metastasis, 参与, 其他, 2023-07--2028-06