基本信息
于永生  男  硕导  中国科学院重庆绿色智能技术研究院
电子邮件: yuyongsheng@cigit.ac.cn
通信地址: 重庆市北碚区方正大道266号
邮政编码:

研究领域

生物大分子的化学生物学、合成生物学,主要从事生物大分子的设计、合成及模块化在肿瘤诊疗、抗菌药物(替抗、减抗)、再生医学等领域研究。




招生信息

   
招生专业
080502-材料学
招生方向
肿瘤诊疗,抗菌药物,再生医学
化学生物学
合成生物学

教育背景

2012-08--2015-08   香港中文大学   博士

工作经历

   
工作简历
2022-03~现在, 中国科学院重庆绿色智能技术研究院, 副研究员
社会兼职
2021-09-03-2022-07-31,客座编辑,

专利与奖励

   

出版信息

   
发表论文
(1) Glutathione-Responsive and Hydrogen Sulfide Self-Generating Nanocages Based on Self-Weaving Technology To Optimize Cancer Immunotherapy, Acs Nano, 2024, 通讯作者
(2) Thiourea‐Cation Chelation Based Hydrogel and its Application as Antibacterial Dressing for the Repair of Diabetic Wound, Advanced Functional Materials, 2024, 通讯作者
(3) Bioresponsive Self-Reinforcing Sericin/Silk Fibroin Hydrogel for Relieving the Immune-Related Adverse Events in Tumor Immunotherapy, Advanced Functional Materials, 2023, 通讯作者
(4) Functionalized human umbilical cord mesenchymal stem cells and injectable HA/Gel hydrogel synergy in endometrial repair and fertility recovery, Acta Biomaterialia, 2023, 通讯作者
(5) A Review of Nanotechnology for Treating Dysfunctional Placenta, Frontiers in Bioengineering and Biotechnology, 2022, 通讯作者
(6) Editorial: Biomedical applications of natural polymers, Frontiers in Bioengineering and Biotechnology, 2022, 通讯作者
(7) Highly Transparent, Self-Healing, and Self-Adhesive Double Network Hydrogel for Wearable Sensors, Frontiers in Bioengineering and Biotechnology, 2022, 通讯作者
(8) Ultra-stretchable, adhesive, and self-healing MXene/polyampholytes hydrogel as flexible and wearable epidermal sensors, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2022, 通讯作者
(9) Controllable Drug Delivery by Na plus /K plus ATPase alpha 1 Targeting Peptide Conjugated DSPE-PEG Nanocarriers for Breast Cancer, Technology in Cancer Research & Treatment, 2021, 通讯作者
(10) Dimer targeting peptide mediated precise and controllable drug delivery by upconversion nanocarriers for breast cancer therapy, Materials & Design, 2021, 通讯作者
(11) Nanobody Conjugates for Targeted Cancer Therapy and Imaging, Technology in Cancer Research & Treatment, 2021, 通讯作者
(12) Proximity-induced Covalent Peptide for Selective Inhibition of MDA-9 in Breast Cancer Cells, BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2020, 通讯作者
(13) MiR-101-3p and Syn-Cal14.1a Synergy in Suppressing EZH2-Induced Progression of Breast Cancer, OncoTargets and Therapy, 2020, 通讯作者
(14) Mimicking the Endometrial Cancer Tumor Microenvironment to Reprogram Tumor-Associated Macrophages in Disintegrable Supramolecular Gelatin Hydrogel, International Journal of Nanomedicine, 2020, 通讯作者
(15) Inhibition of protein FAK enhances 5-FU chemosensitivity to gastric carcinoma via p53 signaling pathways, Computational and Structural Biotechnology Journal, 2020, 通讯作者
(16) Carcinogenic roles and therapeutic effects of EZH2 in gynecological cancers, Bioorganic & Medicinal Chemistry, 2020, 通讯作者
(17) A PDZ Protein MDA-9/Syntenin: As a Target for Cancer Therapy, Computational and Structural Biotechnology Journal, 2019, 第 1 作者
(18) Syntenin-targeted peptide blocker inhibits progression of cancer cells, European Journal of Medicinal Chemistry, 2018, 通讯作者
(19) Targeted Covalent Inhibition of Grb2-Sos1 Interaction through Proximity-Induced Conjugation in Breast Cancer Cells, Molecular Pharmaceutics, 2017, 第 1 作者
(20) Pdz-reactive peptide activates ephrin-b reverse signaling and inhibits neuronal chemotaxis, ACS Chemical Biology, 2016, 第 1 作者
(21) Affinity-guided protein conjugation: the trilogy of covalent protein labeling,assembly and inhibition, Science China-Chemistry, 2016, 第 1 作者
(22) Functional Assembly of Protein Fragments Induced by Spatial Confinement, PLoS ONE, 2015, 第 1 作者
(23) Inhibition of hepatocellular carcinoma growth using immunoliposomes for co-delivery of adriamycin and ribonucleotide reductase M2 siRNA, Biomaterials, 2013, 第 1 作者
(24) EGFR-specific PEGylated immunoliposomes for active siRNA delivery in hepatocellular carcinoma, Biomaterials, 2012, 第 1 作者
发表著作
(1) 生物医用材料(组织再生与肿瘤治疗), Bio-medical Materials(Tissue regeneration and tumor treatment), 上海交通大学出版社, 2024-03, 第 其他 作者

科研活动