基本信息
易宇 男 硕导 国家纳米科学中心
电子邮件： yiyu@nanoctr.cn
通信地址： 北京市海淀区中关村北一条11号国家纳米科学中心
邮政编码： 100190
电子邮件： yiyu@nanoctr.cn
通信地址： 北京市海淀区中关村北一条11号国家纳米科学中心
邮政编码： 100190
研究领域
生物医用纳米材料，硒肽的自组装与生物效应，超分子化学
招生信息
招生专业
0805J1-纳米科学与技术
070305-高分子化学与物理
083100-生物医学工程
070305-高分子化学与物理
083100-生物医学工程
招生方向
超分子自组装
生物医用纳米材料
单原子催化材料
生物医用纳米材料
单原子催化材料
教育背景
2013-10--2016-09 东京大学 博士
2010-09--2013-07 清华大学 硕士
2006-08--2010-07 清华大学 学士
2010-09--2013-07 清华大学 硕士
2006-08--2010-07 清华大学 学士
工作经历
工作简历
2018-01~现在, 国家纳米科学中心, 副研究员
2016-11~2017-12,东京大学, 博士后
2016-11~2017-12,东京大学, 博士后
专利与奖励
专利成果
[1] 王浩, 易宇. 一种靶向血管细胞黏附分子-1的自组装硒肽、硒肽纳米药物及其制备方法和应用. CN: CN115353550A, 2022-11-18.
[2] 戎宏盼, 刘山歌, 张加涛, 易宇. 空心氮掺杂碳球负载单原子钆造影剂的制备方法及应用. CN: CN113694219A, 2021-11-26.
[3] 王浩, 易宇, 魏子钰. 一种硒肽及其制备方法和应用. CN: CN112472815A, 2021-03-12.
[4] 许华平, 曾令武, 曹玮, 易宇. 含硒化合物及其制备方法、药物组合物. CN: CN103113277A, 2013-05-22.
[2] 戎宏盼, 刘山歌, 张加涛, 易宇. 空心氮掺杂碳球负载单原子钆造影剂的制备方法及应用. CN: CN113694219A, 2021-11-26.
[3] 王浩, 易宇, 魏子钰. 一种硒肽及其制备方法和应用. CN: CN112472815A, 2021-03-12.
[4] 许华平, 曾令武, 曹玮, 易宇. 含硒化合物及其制备方法、药物组合物. CN: CN103113277A, 2013-05-22.
出版信息
发表论文
[1] Liu, Shange, Jiang, Yuxing, Liu, Pengcheng, Yi, Yu, Hou, Dayong, Li, You, Liang, Xiao, Wang, Yifan, Li, Zhi, He, Jia, Rong, Hongpan, Wang, Dingsheng, Zhang, Jiatao. Single-Atom Gadolinium Nano-Contrast Agents with High Stability for Tumor T1 Magnetic Resonance Imaging. ACS NANO[J]. 2023, 第 4 作者 通讯作者 17(9): 8053-8063, http://dx.doi.org/10.1021/acsnano.2c09664.
[2] Yang, PeiPei, Ye, XinWei, Liu, MeiQin, Yang, JinXuan, Feng, XiaoLi, Li, YiJing, Zhang, Kuo, Liang, HongWen, Yi, Yu, Wang, Lei, Liu, YiXuan, Yang, XingLou, Shi, ZhengLi, Feng, LiQiang, Chen, Ling, Xue, Yintong, PanHammarstrom, Qiang, Wang, Hao, Zhao, Yuliang. Entangling of Peptide Nanofibers Reduces the Invasiveness of SARS-CoV-2. ADVANCED HEALTHCARE MATERIALS[J]. 2023, 第 9 作者12(24): http://dx.doi.org/10.1002/adhm.202300673.
[3] Jiang, Yuxing, Rong, Hongtao, Wang, Yifan, Liu, Shange, Xu, Peng, Luo, Zhen, Guo, Lamei, Zhu, Tao, Rong, Hongpan, Wang, Dingsheng, Zhang, Jiatao, Yi, Yu, Wang, Hao. Single-atom cobalt nanozymes promote spinal cord injury recovery by anti-oxidation and neuroprotection. NANO RESEARCH[J]. 2023, 第 12 作者 通讯作者 16(7): 9752-9759, http://lib.cqvip.com/Qikan/Article/Detail?id=7110124920.
[4] Yi, Yu, An, HongWei, Wang, Hao. Intelligent Biomaterialomics: Molecular Design, Manufacturing, and Biomedical Applications. ADVANCED MATERIALS. 2023, 第 1 作者http://dx.doi.org/10.1002/adma.202305099.
[5] Wei, Ziyu, Yi, Yu, Luo, Zhen, Gong, Xiaoyun, Jiang, Yuxing, Hou, Dayong, Zhang, Li, Liu, Zimo, Wang, Mandi, Wang, Jie, Guo, Ruochen, Yang, Jinjun, Wang, Lei, Wang, Hao, Zhao, Yuliang. Selenopeptide Nanomedicine Activates Natural Killer Cells for Enhanced Tumor Chemoimmunotherapy. ADVANCED MATERIALS[J]. 2022, 第 2 作者 通讯作者 34(17): 2108167,
[6] Liang, HongWen, Jia, Tian, Yong, Xue, Yu, JingKun, Yi, Yu, Lu, Siyu, Wang, Lei, Wang, Hao. Photoinduced Single-Crystal to Single-Crystal Transformation via Conformational Change with Turn-On Fluorescence. CRYSTAL GROWTH & DESIGN[J]. 2022, 第 5 作者22(4): 2082-2086, http://dx.doi.org/10.1021/acs.cgd.2c00179.
[7] Fan, Yu, Liu, Shange, Yi, Yu, Rong, Hongpan, Zhang, Jiatao. Catalytic Nanomaterials toward Atomic Levels for Biomedical Applications: From Metal Clusters to Single-Atom Catalysts. ACS NANO[J]. 2021, 第 3 作者 通讯作者 15(2): 2005-2037, https://www.webofscience.com/wos/woscc/full-record/WOS:000623061800007.
[8] Hua Wang, Han Wu, Yu Yi, Ke-Fei Xue, Hao Wang, Yuliang Zhao, Xi Zhang. Self-Motivated Supramolecular Combination Chemotherapy for Overcoming Drug Resistance Based on Acid-Activated Competition of Host-Guest Interactions. CCSCHEMISTRY[J]. 2021, 第 3 作者 通讯作者 3: 1413-1425,
[9] Zhen Luo, Yujuan Gao, Zhongyu Duan, Yu Yi, Hao Wang. Mitochondria-Targeted Self-Assembly of Peptide-Based Nanomaterials. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY[J]. 2021, 第 4 作者 通讯作者 9: 782234,
[10] Kim, Beob Soo, Naito, Mitsuru, Chaya, Hiroyuki, Hori, Mao, Hayashi, Kotaro, Min, Hyun Su, Yi, Yu, Kim, Hyun Jin, Nagata, Tetsuya, Anraku, Yasutaka, Kishimura, Akihiro, Kataoka, Kazunori, Miyata, Kanjiro. Noncovalent Stabilization of Vesicular Polyion Complexes with Chemically Modified/Single-Stranded Oligonucleotides and PEG-b-guanidinylated Polypeptides for Intracavity Encapsulation of Effector Enzymes Aimed at Cooperative Gene Knockdown. BIOMACROMOLECULES[J]. 2020, 第 7 作者21(10): 4365-4376, https://www.webofscience.com/wos/woscc/full-record/WOS:000580890000039.
[11] Hua Wang, Ya-Qiong Yan, Yu Yi, Zi-Yu Wei, Hao Chen, Jiang-Fei Xu, Hao Wang, Yuliang Zhao, Xi Zhang. Supramolecular Peptide Therapeutics: Host–Guest Interaction-Assisted Systemic Delivery of Anticancer Peptides. CCS Chemistry[J]. 2020, 第 3 作者 通讯作者 2: 739-748,
[12] Yang, PeiPei, Zhang, Kuo, He, PingPing, Fan, Yu, Gao, Xuejiao J, Gao, Xingfa, Chen, ZiMing, Hou, DaYong, Li, Yuan, Yi, Yu, Cheng, DongBing, Zhang, JingPing, Shi, Linqi, Zhang, XianZheng, Wang, Lei, Wang, Hao. A biomimetic platelet based on assembling peptides initiates artificial coagulation. SCIENCE ADVANCES[J]. 2020, 第 10 作者6(22): https://www.webofscience.com/wos/woscc/full-record/WOS:000537238200014.
[13] Yi, Yu, Kim, Hyun Jin, Zheng, Meng, Mi, Peng, Naito, Mitsuru, Kim, Beob Soo, Min, Hyun Su, Hayashi, Kotaro, Perche, Federico, Toh, Kazuko, Liu, Xueying, Mochida, Yuki, Kinoh, Hiroaki, Cabral, Horacio, Miyata, Kanjiro, Kataoka, Kazunori. Glucose-linked sub-50-nm unimer polyion complex-assembled gold nanoparticles for targeted siRNA delivery to glucose transporter 1-overexpressing breast cancer stem-like cells. JOURNAL OF CONTROLLED RELEASE[J]. 2019, 第 1 作者295: 268-277, http://dx.doi.org/10.1016/j.jconrel.2019.01.006.
[14] Kim, Beob Soo, Kim, Hyun Jin, Osawa, Shigehito, Hayashi, Kotaro, Toh, Kazuko, Naito, Mitsuru, Min, Hyun Su, Yi, Yu, Kwon, Ick Chan, Kataoka, Kazunori, Miyata, Kanjiro. Dually Stabilized Triblock Copolymer Micelles with Hydrophilic Shell and Hydrophobic Interlayer for Systemic Antisense Oligonucleotide Delivery to Solid Tumor. ACS BIOMATERIALS SCIENCE & ENGINEERING[J]. 2019, 第 8 作者5(11): 5770-5780,
[15] Kim, Hyun Jin, Yi, Yu, Kim, Ahram, Miyata, Kanjiro. Small Delivery Vehicles of siRNA for Enhanced Cancer Targeting. BIOMACROMOLECULES. 2018, 第 2 作者19(7): 2377-2390, https://www.webofscience.com/wos/woscc/full-record/WOS:000438470800003.
[16] Yi, Yu, Lin, Gan, Chen, Shaoyi, Liu, Jing, Zhang, Huaping, Mi, Peng. Polyester micelles for drug delivery and cancer theranostics: Current achievements, progresses and future perspectives. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS. 2018, 第 1 作者83: 218-232, http://dx.doi.org/10.1016/j.msec.2017.10.004.
[17] Zheng, Meng, Kim, Hyun Jin, Oosawa, Shigehito, Yi, Yu, Miyata, Kanjiro, Kataoka, Kazunori. Unimer polyion complex self-assembled nanomicelle for systemic delivery of siRNA into solid tumor. JOURNAL OF CONTROLLED RELEASE. 2017, 第 4 作者259: E91-E92, http://dx.doi.org/10.1016/j.jconrel.2017.03.197.
[18] Perche, F, Yi, Y, Hespel, L, Mi, P, Dirisala, A, Cabral, H, Miyata, K, Kataoka, K. Hydroxychloroquine-conjugated gold nanoparticles for improved siRNA activity. BIOMATERIALS[J]. 2016, 90: 62-71, http://dx.doi.org/10.1016/j.biomaterials.2016.02.027.
[19] Ishii, Takehiko, Miyata, Kanjiro, Anraku, Yasutaka, Naito, Mitsuru, Yi, Yu, Jinbo, Takao, Takae, Seiji, Fukusato, Yu, Hori, Mao, Osada, Kensuke, Kataoka, Kazunori. Enhanced target recognition of nanoparticles by cocktail PEGylation with chains of varying lengths. CHEMICAL COMMUNICATIONS[J]. 2016, 第 5 作者52(7): 1517-1519, https://www.webofscience.com/wos/woscc/full-record/WOS:000368352900049.
[20] Yi, Yu, Kim, Hyun Jin, Mi, Peng, Zheng, Meng, Takemoto, Hiroyasu, Toh, Kazuko, Kim, Beob Soo, Hayashi, Kotaro, Naito, Mitsuru, Matsumoto, Yu, Miyata, Kanjiro, Kataoka, Kazunori. Targeted systemic delivery of siRNA to cervical cancer model using cyclic RGD-installed unimer polyion complex-assembled gold nanoparticles. JOURNAL OF CONTROLLED RELEASE[J]. 2016, 第 1 作者244: 247-256, http://dx.doi.org/10.1016/j.jconrel.2016.08.041.
[21] Nishida, Haruka, Matsumoto, Yoko, Kawana, Kei, Christie, R James, Naito, Mitsuru, Kim, Beob Soo, Toh, Kazuko, Min, Hyun Su, Yi, Yu, Matsumoto, Yu, Kim, Hyun Jin, Miyata, Kanjiro, Taguchi, Ayumi, Tomio, Kensuke, Yamashita, Aki, Inoue, Tomoko, Nakamura, Hiroe, Fujimoto, Asaha, Sato, Masakazu, Yoshida, Mitsuyo, Adachi, Katsuyuki, Arimoto, Takahide, WadaHiraike, Osamu, Oda, Katsutoshi, Nagamatsu, Takeshi, Nishiyama, Nobuhiro, Kataoka, Kazunori, Osuga, Yutaka, Fujii, Tomoyuki. Systemic delivery of siRNA by actively targeted polyion complex micelles for silencing the E6 and E7 human papillomavirus oncogenes. JOURNAL OF CONTROLLED RELEASE[J]. 2016, 第 9 作者231: 29-37, http://dx.doi.org/10.1016/j.jconrel.2016.03.016.
[22] Li, Tianyu, Li, Feng, Xiang, Wentian, Yi, Yu, Chen, Yuyan, Cheng, Liang, Liu, Zhuang, Xu, Huaping. Selenium-Containing Amphiphiles Reduced and Stabilized Gold Nanoparticles: Kill Cancer Cells via Reactive Oxygen Species. ACS APPLIED MATERIALS & INTERFACES[J]. 2016, 第 4 作者8(34): 22106-22112, https://www.webofscience.com/wos/woscc/full-record/WOS:000382514100031.
[23] Wang, Lu, Cao, Wei, Yi, Yu, Xu, Huaping. Dual Redox Responsive Coassemblies of Diselenide-Containing Block Copolymers and Polymer Lipids. LANGMUIR[J]. 2014, 第 3 作者30(19): 5628-5636, https://www.webofscience.com/wos/woscc/full-record/WOS:000336414500035.
[24] Kim, Hyun Jin, Takemoto, Hiroyasu, Yi, Yu, Zheng, Meng, Maeda, Yoshinori, Chaya, Hiroyuki, Hayashi, Kotaro, Mi, Peng, Pittella, Frederico, Christie, R James, Toh, Kazuko, Matsumoto, Yu, Nishiyama, Nobuhiro, Miyata, Kanjiro, Kataoka, Kazunori. Precise Engineering of siRNA Delivery Vehicles to Tumors Using Polyion Complexes and Gold Nanoparticles. ACS NANO[J]. 2014, 第 3 作者8(9): 8979-8991, https://www.webofscience.com/wos/woscc/full-record/WOS:000342184400026.
[25] Zeng, Lingwu, Li, Yang, Li, Tianyu, Cao, Wei, Yi, Yu, Geng, Weijia, Sun, Zhiwei, Xu, Huaping. Selenium-Platinum Coordination Compounds as Novel Anticancer Drugs: Selectively Killing Cancer Cells via a Reactive Oxygen Species (ROS)-Mediated Apoptosis Route. CHEMISTRY-AN ASIAN JOURNAL[J]. 2014, 第 5 作者9(8): 2295-2302, https://www.webofscience.com/wos/woscc/full-record/WOS:000342675900043.
[26] Li Tianyu, Yi Yu, Xu Huaping. Selenium-containing Coordinating Assemblies with Selective Anti-cancer Activity: the Control of Reactive Oxygen Species. ACTA CHIMICA SINICA[J]. 2014, 第 2 作者72(10): 1079-1084, https://www.webofscience.com/wos/woscc/full-record/WOS:000345818800004.
[27] Ding, Yan, Yi, Yu, Xu, Huaping, Wang, Zhiqiang, Zhang, Xi. Redox-responsive thermal sensitivity based on a selenium-containing small molecule. CHEMICAL COMMUNICATIONS[J]. 2014, 第 2 作者50(20): 2585-2588, https://www.webofscience.com/wos/woscc/full-record/WOS:000331175100008.
[28] Li Tianyu, Yi Yu, Xu Huaping. Selenium-containing Coordinating Assemblies with Selective Anti-cancer Activity: the Control of Reactive Oxygen Species. ACTA CHIMICA SINICA[J]. 2014, 第 2 作者72(10): 1079-1084, https://www.webofscience.com/wos/woscc/full-record/WOS:000345818800004.
[29] Yi, Yu, Xu, Huaping, Wang, Lu, Cao, Wei, Zhang, Xi. A New Dynamic Covalent Bond of SeN: Towards Controlled Self-Assembly and Disassembly. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2013, 第 1 作者19(29): 9506-9510, https://www.webofscience.com/wos/woscc/full-record/WOS:000321431600020.
[30] Yi, Yu, Fa, Shixin, Cao, Wei, Zeng, Lingwu, Wang, Meixiang, Xu, Huaping, Zhang, Xi. Fabrication of well-defined crystalline azacalixarene nanosheets assisted by Se center dot center dot center dot N non-covalent interactions. CHEMICAL COMMUNICATIONS[J]. 2012, 第 1 作者48(60): 7495-7497, https://www.webofscience.com/wos/woscc/full-record/WOS:000305883400021.
[31] Cao, Wei, Li, Yang, Yi, Yu, Ji, Shaobo, Zeng, Lingwu, Sun, Zhiwei, Xu, Huaping. Coordination-responsive selenium-containing polymer micelles for controlled drug release. CHEMICAL SCIENCE[J]. 2012, 第 3 作者3(12): 3403-3408, https://www.webofscience.com/wos/woscc/full-record/WOS:000311920500009.
[32] Liu, Zhihua, Yi, Yu, Gauczinski, Jan, Xu, Huaping, Schoenhoff, Monika, Zhang, Xi. Surface Molecular Imprinted Layer-by-Layer Film Attached to a Porous Membrane for Selective Filtration. LANGMUIR[J]. 2011, 第 2 作者27(19): 11806-11812, https://www.webofscience.com/wos/woscc/full-record/WOS:000295187300013.
[33] Liu, Zhihua, Yi, Yu, Xu, Huaping, Zhang, Xi, Ngo, Thien Huynh, Smet, Mario. Cation-Selective Microcontact Printing Based on Surface-Molecular-Imprinted Layer-by-Layer Films. ADVANCED MATERIALS[J]. 2010, 第 2 作者22(24): 2689-+, http://www.corc.org.cn/handle/1471x/2414738.
[2] Yang, PeiPei, Ye, XinWei, Liu, MeiQin, Yang, JinXuan, Feng, XiaoLi, Li, YiJing, Zhang, Kuo, Liang, HongWen, Yi, Yu, Wang, Lei, Liu, YiXuan, Yang, XingLou, Shi, ZhengLi, Feng, LiQiang, Chen, Ling, Xue, Yintong, PanHammarstrom, Qiang, Wang, Hao, Zhao, Yuliang. Entangling of Peptide Nanofibers Reduces the Invasiveness of SARS-CoV-2. ADVANCED HEALTHCARE MATERIALS[J]. 2023, 第 9 作者12(24): http://dx.doi.org/10.1002/adhm.202300673.
[3] Jiang, Yuxing, Rong, Hongtao, Wang, Yifan, Liu, Shange, Xu, Peng, Luo, Zhen, Guo, Lamei, Zhu, Tao, Rong, Hongpan, Wang, Dingsheng, Zhang, Jiatao, Yi, Yu, Wang, Hao. Single-atom cobalt nanozymes promote spinal cord injury recovery by anti-oxidation and neuroprotection. NANO RESEARCH[J]. 2023, 第 12 作者 通讯作者 16(7): 9752-9759, http://lib.cqvip.com/Qikan/Article/Detail?id=7110124920.
[4] Yi, Yu, An, HongWei, Wang, Hao. Intelligent Biomaterialomics: Molecular Design, Manufacturing, and Biomedical Applications. ADVANCED MATERIALS. 2023, 第 1 作者http://dx.doi.org/10.1002/adma.202305099.
[5] Wei, Ziyu, Yi, Yu, Luo, Zhen, Gong, Xiaoyun, Jiang, Yuxing, Hou, Dayong, Zhang, Li, Liu, Zimo, Wang, Mandi, Wang, Jie, Guo, Ruochen, Yang, Jinjun, Wang, Lei, Wang, Hao, Zhao, Yuliang. Selenopeptide Nanomedicine Activates Natural Killer Cells for Enhanced Tumor Chemoimmunotherapy. ADVANCED MATERIALS[J]. 2022, 第 2 作者 通讯作者 34(17): 2108167,
[6] Liang, HongWen, Jia, Tian, Yong, Xue, Yu, JingKun, Yi, Yu, Lu, Siyu, Wang, Lei, Wang, Hao. Photoinduced Single-Crystal to Single-Crystal Transformation via Conformational Change with Turn-On Fluorescence. CRYSTAL GROWTH & DESIGN[J]. 2022, 第 5 作者22(4): 2082-2086, http://dx.doi.org/10.1021/acs.cgd.2c00179.
[7] Fan, Yu, Liu, Shange, Yi, Yu, Rong, Hongpan, Zhang, Jiatao. Catalytic Nanomaterials toward Atomic Levels for Biomedical Applications: From Metal Clusters to Single-Atom Catalysts. ACS NANO[J]. 2021, 第 3 作者 通讯作者 15(2): 2005-2037, https://www.webofscience.com/wos/woscc/full-record/WOS:000623061800007.
[8] Hua Wang, Han Wu, Yu Yi, Ke-Fei Xue, Hao Wang, Yuliang Zhao, Xi Zhang. Self-Motivated Supramolecular Combination Chemotherapy for Overcoming Drug Resistance Based on Acid-Activated Competition of Host-Guest Interactions. CCSCHEMISTRY[J]. 2021, 第 3 作者 通讯作者 3: 1413-1425,
[9] Zhen Luo, Yujuan Gao, Zhongyu Duan, Yu Yi, Hao Wang. Mitochondria-Targeted Self-Assembly of Peptide-Based Nanomaterials. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY[J]. 2021, 第 4 作者 通讯作者 9: 782234,
[10] Kim, Beob Soo, Naito, Mitsuru, Chaya, Hiroyuki, Hori, Mao, Hayashi, Kotaro, Min, Hyun Su, Yi, Yu, Kim, Hyun Jin, Nagata, Tetsuya, Anraku, Yasutaka, Kishimura, Akihiro, Kataoka, Kazunori, Miyata, Kanjiro. Noncovalent Stabilization of Vesicular Polyion Complexes with Chemically Modified/Single-Stranded Oligonucleotides and PEG-b-guanidinylated Polypeptides for Intracavity Encapsulation of Effector Enzymes Aimed at Cooperative Gene Knockdown. BIOMACROMOLECULES[J]. 2020, 第 7 作者21(10): 4365-4376, https://www.webofscience.com/wos/woscc/full-record/WOS:000580890000039.
[11] Hua Wang, Ya-Qiong Yan, Yu Yi, Zi-Yu Wei, Hao Chen, Jiang-Fei Xu, Hao Wang, Yuliang Zhao, Xi Zhang. Supramolecular Peptide Therapeutics: Host–Guest Interaction-Assisted Systemic Delivery of Anticancer Peptides. CCS Chemistry[J]. 2020, 第 3 作者 通讯作者 2: 739-748,
[12] Yang, PeiPei, Zhang, Kuo, He, PingPing, Fan, Yu, Gao, Xuejiao J, Gao, Xingfa, Chen, ZiMing, Hou, DaYong, Li, Yuan, Yi, Yu, Cheng, DongBing, Zhang, JingPing, Shi, Linqi, Zhang, XianZheng, Wang, Lei, Wang, Hao. A biomimetic platelet based on assembling peptides initiates artificial coagulation. SCIENCE ADVANCES[J]. 2020, 第 10 作者6(22): https://www.webofscience.com/wos/woscc/full-record/WOS:000537238200014.
[13] Yi, Yu, Kim, Hyun Jin, Zheng, Meng, Mi, Peng, Naito, Mitsuru, Kim, Beob Soo, Min, Hyun Su, Hayashi, Kotaro, Perche, Federico, Toh, Kazuko, Liu, Xueying, Mochida, Yuki, Kinoh, Hiroaki, Cabral, Horacio, Miyata, Kanjiro, Kataoka, Kazunori. Glucose-linked sub-50-nm unimer polyion complex-assembled gold nanoparticles for targeted siRNA delivery to glucose transporter 1-overexpressing breast cancer stem-like cells. JOURNAL OF CONTROLLED RELEASE[J]. 2019, 第 1 作者295: 268-277, http://dx.doi.org/10.1016/j.jconrel.2019.01.006.
[14] Kim, Beob Soo, Kim, Hyun Jin, Osawa, Shigehito, Hayashi, Kotaro, Toh, Kazuko, Naito, Mitsuru, Min, Hyun Su, Yi, Yu, Kwon, Ick Chan, Kataoka, Kazunori, Miyata, Kanjiro. Dually Stabilized Triblock Copolymer Micelles with Hydrophilic Shell and Hydrophobic Interlayer for Systemic Antisense Oligonucleotide Delivery to Solid Tumor. ACS BIOMATERIALS SCIENCE & ENGINEERING[J]. 2019, 第 8 作者5(11): 5770-5780,
[15] Kim, Hyun Jin, Yi, Yu, Kim, Ahram, Miyata, Kanjiro. Small Delivery Vehicles of siRNA for Enhanced Cancer Targeting. BIOMACROMOLECULES. 2018, 第 2 作者19(7): 2377-2390, https://www.webofscience.com/wos/woscc/full-record/WOS:000438470800003.
[16] Yi, Yu, Lin, Gan, Chen, Shaoyi, Liu, Jing, Zhang, Huaping, Mi, Peng. Polyester micelles for drug delivery and cancer theranostics: Current achievements, progresses and future perspectives. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS. 2018, 第 1 作者83: 218-232, http://dx.doi.org/10.1016/j.msec.2017.10.004.
[17] Zheng, Meng, Kim, Hyun Jin, Oosawa, Shigehito, Yi, Yu, Miyata, Kanjiro, Kataoka, Kazunori. Unimer polyion complex self-assembled nanomicelle for systemic delivery of siRNA into solid tumor. JOURNAL OF CONTROLLED RELEASE. 2017, 第 4 作者259: E91-E92, http://dx.doi.org/10.1016/j.jconrel.2017.03.197.
[18] Perche, F, Yi, Y, Hespel, L, Mi, P, Dirisala, A, Cabral, H, Miyata, K, Kataoka, K. Hydroxychloroquine-conjugated gold nanoparticles for improved siRNA activity. BIOMATERIALS[J]. 2016, 90: 62-71, http://dx.doi.org/10.1016/j.biomaterials.2016.02.027.
[19] Ishii, Takehiko, Miyata, Kanjiro, Anraku, Yasutaka, Naito, Mitsuru, Yi, Yu, Jinbo, Takao, Takae, Seiji, Fukusato, Yu, Hori, Mao, Osada, Kensuke, Kataoka, Kazunori. Enhanced target recognition of nanoparticles by cocktail PEGylation with chains of varying lengths. CHEMICAL COMMUNICATIONS[J]. 2016, 第 5 作者52(7): 1517-1519, https://www.webofscience.com/wos/woscc/full-record/WOS:000368352900049.
[20] Yi, Yu, Kim, Hyun Jin, Mi, Peng, Zheng, Meng, Takemoto, Hiroyasu, Toh, Kazuko, Kim, Beob Soo, Hayashi, Kotaro, Naito, Mitsuru, Matsumoto, Yu, Miyata, Kanjiro, Kataoka, Kazunori. Targeted systemic delivery of siRNA to cervical cancer model using cyclic RGD-installed unimer polyion complex-assembled gold nanoparticles. JOURNAL OF CONTROLLED RELEASE[J]. 2016, 第 1 作者244: 247-256, http://dx.doi.org/10.1016/j.jconrel.2016.08.041.
[21] Nishida, Haruka, Matsumoto, Yoko, Kawana, Kei, Christie, R James, Naito, Mitsuru, Kim, Beob Soo, Toh, Kazuko, Min, Hyun Su, Yi, Yu, Matsumoto, Yu, Kim, Hyun Jin, Miyata, Kanjiro, Taguchi, Ayumi, Tomio, Kensuke, Yamashita, Aki, Inoue, Tomoko, Nakamura, Hiroe, Fujimoto, Asaha, Sato, Masakazu, Yoshida, Mitsuyo, Adachi, Katsuyuki, Arimoto, Takahide, WadaHiraike, Osamu, Oda, Katsutoshi, Nagamatsu, Takeshi, Nishiyama, Nobuhiro, Kataoka, Kazunori, Osuga, Yutaka, Fujii, Tomoyuki. Systemic delivery of siRNA by actively targeted polyion complex micelles for silencing the E6 and E7 human papillomavirus oncogenes. JOURNAL OF CONTROLLED RELEASE[J]. 2016, 第 9 作者231: 29-37, http://dx.doi.org/10.1016/j.jconrel.2016.03.016.
[22] Li, Tianyu, Li, Feng, Xiang, Wentian, Yi, Yu, Chen, Yuyan, Cheng, Liang, Liu, Zhuang, Xu, Huaping. Selenium-Containing Amphiphiles Reduced and Stabilized Gold Nanoparticles: Kill Cancer Cells via Reactive Oxygen Species. ACS APPLIED MATERIALS & INTERFACES[J]. 2016, 第 4 作者8(34): 22106-22112, https://www.webofscience.com/wos/woscc/full-record/WOS:000382514100031.
[23] Wang, Lu, Cao, Wei, Yi, Yu, Xu, Huaping. Dual Redox Responsive Coassemblies of Diselenide-Containing Block Copolymers and Polymer Lipids. LANGMUIR[J]. 2014, 第 3 作者30(19): 5628-5636, https://www.webofscience.com/wos/woscc/full-record/WOS:000336414500035.
[24] Kim, Hyun Jin, Takemoto, Hiroyasu, Yi, Yu, Zheng, Meng, Maeda, Yoshinori, Chaya, Hiroyuki, Hayashi, Kotaro, Mi, Peng, Pittella, Frederico, Christie, R James, Toh, Kazuko, Matsumoto, Yu, Nishiyama, Nobuhiro, Miyata, Kanjiro, Kataoka, Kazunori. Precise Engineering of siRNA Delivery Vehicles to Tumors Using Polyion Complexes and Gold Nanoparticles. ACS NANO[J]. 2014, 第 3 作者8(9): 8979-8991, https://www.webofscience.com/wos/woscc/full-record/WOS:000342184400026.
[25] Zeng, Lingwu, Li, Yang, Li, Tianyu, Cao, Wei, Yi, Yu, Geng, Weijia, Sun, Zhiwei, Xu, Huaping. Selenium-Platinum Coordination Compounds as Novel Anticancer Drugs: Selectively Killing Cancer Cells via a Reactive Oxygen Species (ROS)-Mediated Apoptosis Route. CHEMISTRY-AN ASIAN JOURNAL[J]. 2014, 第 5 作者9(8): 2295-2302, https://www.webofscience.com/wos/woscc/full-record/WOS:000342675900043.
[26] Li Tianyu, Yi Yu, Xu Huaping. Selenium-containing Coordinating Assemblies with Selective Anti-cancer Activity: the Control of Reactive Oxygen Species. ACTA CHIMICA SINICA[J]. 2014, 第 2 作者72(10): 1079-1084, https://www.webofscience.com/wos/woscc/full-record/WOS:000345818800004.
[27] Ding, Yan, Yi, Yu, Xu, Huaping, Wang, Zhiqiang, Zhang, Xi. Redox-responsive thermal sensitivity based on a selenium-containing small molecule. CHEMICAL COMMUNICATIONS[J]. 2014, 第 2 作者50(20): 2585-2588, https://www.webofscience.com/wos/woscc/full-record/WOS:000331175100008.
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[29] Yi, Yu, Xu, Huaping, Wang, Lu, Cao, Wei, Zhang, Xi. A New Dynamic Covalent Bond of SeN: Towards Controlled Self-Assembly and Disassembly. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2013, 第 1 作者19(29): 9506-9510, https://www.webofscience.com/wos/woscc/full-record/WOS:000321431600020.
[30] Yi, Yu, Fa, Shixin, Cao, Wei, Zeng, Lingwu, Wang, Meixiang, Xu, Huaping, Zhang, Xi. Fabrication of well-defined crystalline azacalixarene nanosheets assisted by Se center dot center dot center dot N non-covalent interactions. CHEMICAL COMMUNICATIONS[J]. 2012, 第 1 作者48(60): 7495-7497, https://www.webofscience.com/wos/woscc/full-record/WOS:000305883400021.
[31] Cao, Wei, Li, Yang, Yi, Yu, Ji, Shaobo, Zeng, Lingwu, Sun, Zhiwei, Xu, Huaping. Coordination-responsive selenium-containing polymer micelles for controlled drug release. CHEMICAL SCIENCE[J]. 2012, 第 3 作者3(12): 3403-3408, https://www.webofscience.com/wos/woscc/full-record/WOS:000311920500009.
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[33] Liu, Zhihua, Yi, Yu, Xu, Huaping, Zhang, Xi, Ngo, Thien Huynh, Smet, Mario. Cation-Selective Microcontact Printing Based on Surface-Molecular-Imprinted Layer-by-Layer Films. ADVANCED MATERIALS[J]. 2010, 第 2 作者22(24): 2689-+, http://www.corc.org.cn/handle/1471x/2414738.
科研活动
科研项目
（ 1 ） 新型含硒多肽聚合物的精准合成及其抗癌应用研究, 主持, 国家级, 2019-01--2021-12
（ 2 ） 自组装纳米材料安全性评价, 主持, 国家级, 2019-08--2022-07
（ 3 ） 超分子多肽递送体系在肿瘤治疗与新冠疫苗中的研究, 主持, 国家级, 2022-01--2025-12
（ 2 ） 自组装纳米材料安全性评价, 主持, 国家级, 2019-08--2022-07
（ 3 ） 超分子多肽递送体系在肿瘤治疗与新冠疫苗中的研究, 主持, 国家级, 2022-01--2025-12