General
I worked as Researcher in Key Laboratory of Soybean Molecular Design Breeding, Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, China.


Research Areas

Proteomics, nuclear proteomics, phosphoproteomics, molecular biology.


Education

2013.10-2016. 09 Doctoral Program in Life Sciences and Bioengineering. Graduate School of Life and Environmental Sciences, University of Tsukuba. Japan. PhD degree 

2010.09-2013.07 Master. Study of Plant proteomics in CAS Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture, Wuhan Botanical Garden, Chinese Academy of Science.

2006.09-2010.07 B.A. Biological Sciences College of life science, Anhui normal university.


Experience

   
Work Experience

2023. 05- Till now, Professor, Doctorial Tutor, Principle Investigator in Lab of Soybean Secondary Metabolites and Nutrition, Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences 

2020.07-2023. 05, Associate Researcher, Doctorial Tutor, in State Key Laboratory of Natural Medicines, Department of Pharmacognosy, Institute of Pharmaceutical Science, China Pharmaceutical University.


2016.11-2020. 07, Associate Researcher, Master Tutor, in State Key Laboratory of Natural Medicines, Department of Pharmacognosy, Institute of Pharmaceutical Science, China Pharmaceutical University.


Publications

   
Papers

(1) Xiaojian Yin#,*, Hui Fan#, Yan Chen, Lan-Zhu Li, Wei Song, Yuanming Fan, Wei Zhou, Gaoxiang Ma, Raphael N Alolga, Weiqiang Li, Baolong Zhang, Ping Li, Lam-Son P Tran*, Xu Lu*, Lian-Wen Qi*. Integrative omic and transgenic analyses reveal the positive effect of ultraviolet-B irradiation on salvianolic acid biosynthesis through upregulation of SmNAC1. The Plant Journal, 2020, 104(3):781-799.

(2) Raphael N Alolga#, Yaw Opoku-Damoah#, David A Alagpulinsa#, Feng-Qing Huang, Gaoxiang Ma, Maria A S C Chavez Leon, Chifodya Kudzai, Xiaojian Yin*, Yang Ding*. Metabolomic and transcriptomic analyses of the anti-rheumatoid arthritis potential of xylopic acid in a bioinspired lipoprotein nanoformulation. Biomaterials. 2020, 268:120482.

(3) Lujing Jiang# , Xiaojian Yin# , Ya-Hui Chen, Yan Chen, Wei Jiang, Hao Zheng, Feng-Qing Huang, Baolin Liu, Wei Zhou, Lian-Wen Qi* and Jia Li*. Proteomic analysis reveals ginsenoside Rb1 attenuates myocardial ischemia/reperfusion injury through inhibiting ROS production from mitochondrial complex I. Theranostics, 2021, 11(4): 1703-1720.

(4) Raphael N Alolga, Gloria F Nuer-Allornuvor, Eugene D Kuugbee, Xiaojian Yin*, Gaoxiang Ma*. Ginsenoside Rg1 and the control of inflammation implications for the therapy of type 2 diabetes: A review of scientific findings and call for further research. Pharmacological Research, 2020, 152:104630

(5) Yunxie Wei, Yujing Bai, Xiao Cheng, Russel J Reiter, Xiaojian Yin*, Haitao Shi*. Lighting the way: advances in transcriptional regulation and integrative crosstalk of melatonin biosynthetic enzymes in cassava. Journal of Experimental Botany, 2020, 72(2):161-166

(6) Xiaojian Yin#, Shi-Lei Wang#, Raphael N. Alolga, Enos Mais, Ping Li, Pingfang Yang, Setsuko Komatsu, Lian-Wen Qi*, Label-free proteomic analysis to characterize ginger from China and Ghana. Food Chemistry, 2018, 249: 1-7.

(7) Jia Li#, Ya-Hui Chen#, Lan-Zhu Li#, Feizuo Wang, Wei Song, Raphael N Alolga, Wei Zhou, Heming Yu, Feng-Qing Huang, Xiaojian Yin*. Omics and transgenic analyses reveal that salvianolic acid B exhibits its anti-Inflammatory effects through inhibiting the Mincle-Syk-related pathway in macrophages. Journal of Proteome Research, 2021, 20(7):3734-3748.

(8) Yaping Xiang#, Xiaoxiao Wang#, Wei Song#, Jinfa Du, Xiaojian Yin*. Integrative Omics Analyses Reveal the Effects of Copper Ions on Salvianolic Acid Biosynthesis. Frontiers in Plant Science, 2021, 12:746117.

(9) Xiaojian Yin#, Yunxie Wei#, Wei Song#, He Zhang, Guoyin Liu, Yan Chen, Lan-Zhu Li, Raphael N Alolga, Gaoxiang Ma, Russel J Reiter, Jia Li*, Haitao Shi*. Melatonin as an inducer of arecoline and their coordinated roles in anti-oxidative activity and immune responses. Food & Function, 11(10):8788-8799.

(10) Shijia Liu#, Wei Ji#, Jiawei Lu#, Xiaojun Tang, Yunke Guo, Mingde Ji, Tian Xu, Wanjian Gu, Deshun Kong, Qiuxiang Shen, Dandan Wang, Xiangyu Lv, Jue Wang, Tianyao Zhu, Youjuan Zhu, Ping Liu, Jinfeng Su, Lu Wang, Yuhua Li, Pan Gao, Wei Liu, Lingyun Sun, Xiaojian Yin*, Wei Zhou*. Discovery of Potential Serum Protein Biomarkers in Ankylosing Spondylitis Using Tandem Mass Tag-Based Quantitative Proteomics. Journal of Proteome Research, 2020, 19(2):864-872.

(11) Xu Zhang, Qun Liu, Wei Zhou, Ping Li, Raphael N Alolga, Lian-Wen Qi*, Xiaojian Yin*. A comparative proteomic characterization and nutritional assessment of naturally- and artificially-cultivated Cordyceps sinensis. Journal of Proteomics, 2018, 181:24-35.

(12) Jin Huang, Hui Fan, Xiaojian Yin*, Fang Huang*. Isolation of a Novel Metalloproteinase from Agkistrodon Venom and Its Antithrombotic Activity Analysis. International Journal of Molecular Science, 2019, 20(17):4088.

(13) Xiaojian Yin#, María A S C Chávez León#, Richard Osae, Loveth O Linus, Lian-Wen Qi*, Raphael N Alolga*. Xylopia aethiopica Seeds from Two Countries in West Africa Exhibit Differences in Their Proteomes, Mineral Content and Bioactive Phytochemical Composition. Molecules. 2019, 24(10):1979.

(14) Xiaojian Yin#, Xin Wang#, Setsuko Komatsu*. Phosphoproteomics: Protein Phosphorylation in Regulation of Seed Germination and Plant Growth. Current Protein & Peptide Science. 2018, 19(4):401-412.

(15) Xiaojian Yin#, Setsuko Komatsu* Comprehensive analysis of response and tolerant mechanisms in early-stage soybean at initial-flooding stress. Journal of Proteomics. 2017 169:225-232.

(16) Xiaojian Yin, Susumu Hiraga, Makita Hajika, Minoru Nishimura, Setsuko Komatsu. Transcriptomic analysis reveals the flooding tolerant mechanism in flooding tolerant line and abscisic acid treated soybean. Plant Molecular Biology, 2017, 93(4-5):479-496.

(17) Xiaojian Yin, Setsuko Komatsu*, Nuclear Proteomics Reveals the Role of Protein Synthesis and Chromatin Structure in Root Tip of Soybean during the Initial Stage of Flooding Stress, Journal of Proteome Research, 2016, 15(7):2283–2298.

(18) Xiaojian Yin, Minoru Nishimura, Makita Hajika, Setsuko Komatsu*, Quantitative proteomics reveals the flooding-tolerance mechanism in mutant and abscisic acid-treated soybean, Journal of Proteome Research, 2016, 15(6):2008–2025.

(19) Xiaojian Yin, Setsuko Komatsu*, Quantitative proteomics of nuclear phosphoproteins in the root tip of soybean during the initial stages of flooding stress, Journal of Proteomics, 2015, 119:183-195.

(20) Ming Li#, Xiaojian Yin#, Katsumi Sakata, Pingfang Yang, Setsuko Komatsu*, Proteomic analysis of phosphoproteins in the rice nucleus during early stage of seed germination, Journal of Proteome Research, 2015, 14(7):2884-2896.

(21) Xiaojian Yin, DongLi He, Ravi Gupta, Pingfang Yang*, Physiological and proteomic analyses on artificially aged Brassica napus seed, Frontiers in plant science, 2015, 6:112.

(22) Xiaojian Yin, Katsumi Sakata, Yohei Nanjo, Setsuko Komatsu*, Analysis of initial changes in the proteins of soybean root tip under flooding stress using gel-free and gel-based proteomic techniques, Journal of Proteomics, 2014, 106:1-16.

(23) Xiaojian Yin, Katsumi Sakata, Setsuko Komatsu*, Phosphoproteomics reveals the effect of ethylene in soybean root under flooding stress, Journal of Proteome Research, 2014, 13(12):5618-5634.