基本信息

吴垠  博士、研究员、博士生导师

国家自然科学基金重大研究计划重点项目负责人

广东省特支计划青年拔尖人才、深圳市杰出青年

邮箱:yin.wu@siat.ac.cn

地址:深圳市南山区学苑大道1068号

电话:0755-86392464

研究领域

磁共振成像

医学图像与信号处理

人工智能与医学成像

招生信息

招收博士后、联合培养博士/硕士生(长期有效)

以上申请者请将简历发送至 yin.wu@siat.ac.cn

招生专业
081104-模式识别与智能系统
083100-生物医学工程
085400-电子信息
招生方向
磁共振成像
智能成像与信号处理
分子功能成像

教育背景

2004-09--2008-11   香港大学   博士
2002-09--2004-07   哈尔滨工业大学   硕士
1998-09--2002-07   哈尔滨工业大学   学士

工作经历

2017-12~今,中国科学院深圳先进技术研究院, 研究员
2014-08~2015-08,哈佛医学院/麻省总医院, 国家公派访问学者
2010-02~2017-11,中国科学院深圳先进技术研究院, 副研究员
2009-02~2010-01,中国科学院深圳先进技术研究院, 助理研究员


专利与奖励

   
奖励信息
(1) 超高场人体全身磁共振成像关键技术与应用, 一等奖, 省级, 2022
(2) Summa cum Laude Award, 其他, 2020
(3) Magna cum Laude Award, 其他, 2020
(4) 超导磁共振快速成像关键技术、系统与应用, 一等奖, 省级, 2019
(5) 广东省科技创新青年拔尖人才, 省级, 2017
专利成果
( 1 ) 成像方法、成像装置、电子设备及存储介质, 发明专利, 2022, 第 1 作者, 专利号: CN115054226A

( 2 ) 化学交换特征定量方法及设备, 发明专利, 2021, 第 1 作者, 专利号: CN110824398B

( 3 ) Method for measuring pH, 发明专利, 2021, 第 1 作者, 专利号: US11125843(B2)

( 4 ) 用于磁共振的化学交换饱和转移定量方法、装置及介质, 发明专利, 2021, 第 1 作者, 专利号: CN112748381A

( 5 ) 一种磁共振化学交换饱和转移成像方法以及相关设备, 发明专利, 2021, 第 1 作者, 专利号: CN112731235A

( 6 ) 一种灌注成像方法及装置, 发明专利, 2020, 第 1 作者, 专利号: CN110680325A

( 7 ) 医学图像分割方法、装置、设备及存储介质, 发明专利, 2019, 第 3 作者, 专利号: CN110570394A

( 8 ) pH测定方法, 专利授权, 2018, 第 1 作者, 专利号: CN108195867A

( 9 ) 化学交换饱和转移效应定量方法、装置及电子设备, 专利授权, 2018, 第 1 作者, 专利号: CN108051765A

( 10 ) 一种磁共振心脏血流速度的测量方法及装置, 专利授权, 2017, 第 3 作者, 专利号: CN106923813A

( 11 ) 氨基质子转移效应的确定方法及装置, 专利授权, 2017, 第 1 作者, 专利号: CN106772165A

( 12 ) 心脏电影成像量化方法、呼气末期图像确定方法及装置, 发明专利, 2017, 第 1 作者, 专利号: CN106780467A

( 13 ) 一种医学图像参数的拟合方法和装置, 专利授权, 2017, 第 1 作者, 专利号: CN106682419A

( 14 ) 磁共振成像方法, 发明专利, 2016, 第 6 作者, 专利号: CN105615882A

( 15 ) 磁共振化学交换饱和转移成像方法和系统, 专利授权, 2016, 第 2 作者, 专利号: CN105572613A

( 16 ) 大脑纵向弛豫值测量方法和装置, 专利授权, 2016, 第 2 作者, 专利号: CN105496410A

( 17 ) 用于磁共振化学交换饱和转移成像的CESTR测量方法和系统, 发明专利, 2015, 第 2 作者, 专利号: CN104997511A

( 18 ) 磁共振系统的自适应有源自动匀场方法和系统, 发明专利, 2015, 第 3 作者, 专利号: CN104635187A

( 19 ) 心脏实时电影成像图像处理方法和系统, 发明专利, 2013, 第 1 作者, 专利号: CN103340628A

( 20 ) 平面回波成像方法及系统, 发明专利, 2013, 第 1 作者, 专利号: CN103163496A

( 21 ) 磁共振参数成像方法和系统, 发明专利, 2013, 第 3 作者, 专利号: CN103035017A

( 22 ) 一种心脏磁共振实时电影成像方法、系统, 发明专利, 2013, 第 1 作者, 专利号: CN103006217A

( 23 ) 心脏磁共振实时电影成像的数据处理方法及系统, 发明专利, 2013, 第 1 作者, 专利号: CN103006218A

( 24 ) 磁共振成像采集系统和磁共振成像采集方法, 发明专利, 2013, 第 1 作者, 专利号: CN102920456A

( 25 ) 基于机器学习的并行磁共振成像GRAPPA方法, 发明专利, 2012, 第 3 作者, 专利号: CN102798829A

( 26 ) 磁共振成像方法, 发明专利, 2012, 专利号: CN102129056B

( 27 ) 一种磁共振参数重建方法及系统, 发明专利, 2012, 第 3 作者, 专利号: CN102663701A

( 28 ) 针对小目标的磁共振成像方法和系统, 发明专利, 2012, 第 5 作者, 专利号: CN102525469A

( 29 ) 弥散张量成像方法及系统, 发明专利, 2012, 第 1 作者, 专利号: CN102488519A

( 30 ) 弥散张量成像方法及系统, 发明专利, 2012, 第 1 作者, 专利号: CN102334992A

( 31 ) 弥散张量成像方法及系统, 发明专利, 2012, 第 1 作者, 专利号: CN102309328A

( 32 ) 横向弛豫时间测量方法及系统, 发明专利, 2011, 第 5 作者, 专利号: CN102116856A

( 33 ) 弥散加权成像方法及系统, 发明专利, 2011, 第 5 作者, 专利号: CN102054281A

( 34 ) 磁共振弥散张量成像方法及系统, 发明专利, 2011, 第 2 作者, 专利号: CN102018514A

( 35 ) 磁共振动态成像方法, 发明专利, 2011, 第 6 作者, 专利号: CN102018513A

( 36 ) 磁共振弥散张量成像方法和系统, 发明专利, 2011, 第 1 作者, 专利号: CN102008307A

( 37 ) 多b值弥散张量成像采样方法, 发明专利, 2011, 第 2 作者, 专利号: CN102008308A

( 38 ) 测量肿瘤组织吸入卡波金气体后氧浓度的方法及系统, 发明专利, 2011, 第 5 作者, 专利号: CN102008311A

( 39 ) 磁共振动态成像方法, 发明专利, 2011, 第 6 作者, 专利号: CN102008305A

( 40 ) 磁共振冷却系统及成像装置, 发明专利, 2011, 第 7 作者, 专利号: CN101950007A

( 41 ) 磁共振成像定量参数计算方法及系统, 发明专利, 2010, 第 6 作者, 专利号: CN101912262A

出版信息

   
发表论文
[1] Qiting Wu, Yulong Qi, Pengcheng Gong, Bingsheng Huang, Guanxun Cheng, Dong Liang, Hairong Zheng, Phillip Zhe Sun, Yin Wu. Fast and robust pulsed chemical exchange saturation transfer (CEST) MRI using a quasi-steady-state (QUASS) algorithm at 3T. MAGNETIC RESONANCE IMAGING. 2024, 105: 29-36, http://dx.doi.org/10.1016/j.mri.2023.10.009.
[2] Wu, Yin, Liu, Zhou, Yang, Qian, Zou, Liyan, Zhang, Fan, Qian, Long, Liu, Xin, Zheng, Hairong, Luo, Dehong, Sun, Phillip Zhe. Fast and equilibrium CEST imaging of brain tumor patients at 3T. NEUROIMAGE-CLINICAL[J]. 2022, 33: http://dx.doi.org/10.1016/j.nicl.2021.102890.
[3] Liu, Jie, Xie, ChuanMiao, Liu, Qi, Xu, Jian, Zheng, LiYun, Liu, Xin, Zheng, Hairong, Wu, Yin. Dynamic alteration in myocardium creatine during acute infarction using MR CEST imaging. NMR IN BIOMEDICINE[J]. 2022, 35(7): http://dx.doi.org/10.1002/nbm.4704.
[4] Liu, Zhou, Zou, Liyan, Yang, Qian, Qian, Long, Li, Tianran, Luo, Honghong, Che, Canwen, Lei, Yuanyuan, Chen, Peng, Qiu, Chunyan, Liu, Xin, Wu, Yin, Luo, Dehong. Baseline Amide Proton Transfer Imaging at 3T Fails to Predict Early Response to Induction Chemotherapy in Nasopharyngeal Carcinoma. FRONTIERS IN ONCOLOGY[J]. 2022, 12: http://dx.doi.org/10.3389/fonc.2022.822756.
[5] Zhou, Jinyuan, Zaiss, Moritz, Knutsson, Linda, Sun, Phillip Zhe, Ahn, Sung Soo, Aime, Silvio, Bachert, Peter, Blakeley, Jaishri O, Cai, Kejia, Chappell, Michael A, Chen, Min, Gochberg, Daniel F, Goerke, Steffen, Heo, HyeYoung, Jiang, Shanshan, Jin, Tao, Kim, SeongGi, Laterra, John, Paech, Daniel, Pagel, Mark D, Park, Ji Eun, Reddy, Ravinder, Sakata, Akihiko, SartorettiSchefer, Sabine, Sherry, A Dean, Smith, Seth A, Stanisz, Greg J, Sundgren, Pia C, Togao, Osamu, Vandsburger, Moriel, Wen, Zhibo, Wu, Yin, Zhang, Yi, Zhu, Wenzhen, Zu, Zhongliang, van Zijl, Peter C M. Review and consensus recommendations on clinical APT-weighted imaging approaches at 3T: Application to brain tumors. MAGNETIC RESONANCE IN MEDICINEnull. 2022, 88(2): 546-574, https://www.doi.org/10.1002/mrm.29241.
[6] Liu, Jie, Liu, Hui, Liu, Qi, Xu, Jian, Liu, Xin, Zheng, Hairong, Wu, Yin. Encoding capability prediction of acquisition schedules in CEST MR fingerprinting for pH quantification. MAGNETIC RESONANCE IN MEDICINE[J]. 2022, 87(4): 2044-2052, http://dx.doi.org/10.1002/mrm.29074.
[7] Liu, Zhou, Yang, Qian, Luo, Honghong, Luo, Dehong, Qian, Long, Liu, Xin, Zheng, Hairong, Sun, Phillip Zhe, Wu, Yin. Demonstration of fast and equilibrium human muscle creatine CEST imaging at 3 T. MAGNETIC RESONANCE IN MEDICINE[J]. 2022, 88(1): 322-331, https://www.doi.org/10.1002/mrm.29223.
[8] Xu, Zongwei, Ke, Chao, Liu, Jie, Xu, Shijie, Han, Lujun, Yang, Yadi, Qian, Long, Liu, Xin, Zheng, Hairong, Lv, Xiaofei, Wu, Yin. Diagnostic performance between MR amide proton transfer (APT) and diffusion kurtosis imaging (DKI) in glioma grading and IDH mutation status prediction at 3 T. EUROPEAN JOURNAL OF RADIOLOGY[J]. 2021, 134: http://dx.doi.org/10.1016/j.ejrad.2020.109466.
[9] Zhang, XiaoYong, Zhai, Yuting, Jin, Ziyi, Li, Cong, Sun, Phillip Zhe, Wu, Yin. Preliminary demonstration of in vivo quasi-steady-state CEST postprocessing-Correction of saturation time and relaxation delay for robust quantification of tumor MT and APT effects. MAGNETIC RESONANCE IN MEDICINE[J]. 2021, 86(2): 943-953, http://dx.doi.org/10.1002/mrm.28764.
[10] He, Yangsu, Qin, Wenjian, Wu, Yin, Zhang, Mengxi, Yang, Yongfeng, Liu, Xin, Zheng, Hairong, Liang, Dong, Hu, Zhanli. Automatic left ventricle segmentation from cardiac magnetic resonance images using a capsule network. JOURNAL OF X-RAY SCIENCE AND TECHNOLOGY[J]. 2020, 28(3): 541-553, https://www.webofscience.com/wos/woscc/full-record/WOS:000541717200012.
[11] Liu, Jie, Li, Cong, Chen, Yinsheng, Lv, Xiaofei, Lv, Yanchun, Zhou, Jian, Xi, Shaoyan, Dou, Weiqiang, Qian, Long, Zheng, Hairong, Wu, Yin, Chen, Zhongping. Diagnostic performance of multiparametric MRI in the evaluation of treatment response in glioma patients at 3T. JOURNAL OF MAGNETIC RESONANCE IMAGING[J]. 2020, 51(4): 1154-1161, https://www.webofscience.com/wos/woscc/full-record/WOS:000482288000001.
[12] Qin, Wenjian, Wu, Yin, Li, Siyue, Chen, Yucheng, Yang, Yongfeng, Liu, Xin, Zheng, Hairong, Liang, Dong, Hu, Zhanli. Automated segmentation of the left ventricle from MR cine imaging based on deep learning architecture. BIOMEDICAL PHYSICS & ENGINEERING EXPRESS[J]. 2020, 6(2): [13] Wang, Enfeng, Wu, Yin, Cheung, Jerry S, Igarashi, Takahiro, Wu, Limin, Zhang, Xiaoan, Sun, Phillip Zhe. Mapping tissue pH in an experimental model of acute stroke - Determination of graded regional tissue pH changes with non-invasive quantitative amide proton transfer MRI. NEUROIMAGE[J]. 2019, 191: 610-617, http://dx.doi.org/10.1016/j.neuroimage.2019.02.022.
[14] Wu, Yin, Chen, Yinsheng, Zhao, Yiying, Yang, Shasha, Zhao, Jing, Zhou, Jian, Chen, Zhongping, Sun, Phillip Zhe, Zheng, Hairong. Direct radiofrequency saturation corrected amide proton transfer tumor MRI at 3T. MAGNETIC RESONANCE IN MEDICINE[J]. 2019, 81(4): 2710-2719, [15] 吴垠. Direct saturation corrected amide proton transfer tumor MRI at 3 Tesla. Magnetic Resonance in Medicine. 2019, [16] 郑海荣, 吴垠, 贺强, 李烨, 邹超, 王海峰, 谢强, 余兴恩, 王海宁, 李国斌, 梁栋, 刘新. 基于高场磁共振的快速高分辨成像. 生命科学仪器[J]. 2018, 29-44, http://lib.cqvip.com/Qikan/Article/Detail?id=83667589504849569049484853.
[17] Wu, Yin, Zhou, Iris Yuwen, Lu, Dongshuang, Manderville, Emiri, Lo, Eng H, Zheng, Hairong, Sun, Phillip Zhe. pH-sensitive amide proton transfer effect dominates the magnetization transfer asymmetry contrast during acute ischemiaquantification of multipool contribution to in vivo CEST MRI. MAGNETIC RESONANCE IN MEDICINE[J]. 2018, 79(3): 1602-1608, http://ir.siat.ac.cn:8080/handle/172644/14316.
[18] Wu, Yin, Zhou, Iris Y, Igarashi, Takahiro, Longo, Dario L, Aime, Silvio, Sun, Phillip Zhe. A generalized ratiometric chemical exchange saturation transfer (CEST) MRI approach for mapping renal pH using iopamidol. MAGNETIC RESONANCE IN MEDICINE[J]. 2018, 79(3): 1553-1558, http://ir.siat.ac.cn:8080/handle/172644/14312.
[19] Jiang Ke, Zhu Yanjie, Jia Sen, Wu Yin, Liu Xin, Chung YiuCho. Fast T1 mapping of the brain at high field using Look-Locker and fast imaging. MAGNETIC RESONANCE IMAGING[J]. 2017, 36: 49-55, http://dx.doi.org/10.1016/j.mri.2016.10.022.
[20] Wu, Yin, Wan, Qian, Zhao, Jing, Liu, Xin, Zheng, Hairong, Chung, YiuCho, Chen, Yucheng. Improved Workflow for Quantifying Left Ventricular Function via Cardiorespiratory-Resolved Analysis of Free-Breathing MR Real-Time Cines. JOURNAL OF MAGNETIC RESONANCE IMAGING[J]. 2017, 46(3): 905-914, http://dx.doi.org/10.1002/jmri.25618.
[21] Zhao, Jing, Chen, Yinsheng, Zhao, Yiying, Yang, Shasha, Chen, Zhongping, Wu, Yin, IEEE. Assessment of Chemoradiotherapy Response in Glioma with Magnetic Resonance Amide Proton Transfer Imaging in a Rodent Model. 2017 39TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)null. 2017, 541-543, [22] Yin Wu, Iris Yuwen Zhou, Dongshuang Lu, Emiri Manderville, Eng H Lo, Hairong Zheng, Phillip Zhe Sun. pH-sensitive amide proton transfer (APT) effect dominates the magnetization transfer asymmetry contrast during acute ischemia — Quantification of multi-pool contribution to in vivo CEST MRI. MAGNETIC RESONANCE IN MEDICINE. 2017, 79(3): 1602-1608, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775916/.
[23] Wang, Enfeng, Wu, Yin, Cheung, Jerry S, Zhou, Iris Yuwen, Igarashi, Takahiro, Zhang, XiaoAn, Sun, Phillip Zhe. pH imaging reveals worsened tissue acidification in diffusion kurtosis lesion than the kurtosis/diffusion lesion mismatch in an animal model of acute stroke. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM[J]. 2017, 37(10): 3325-3333, http://www.chinair.org.cn/handle/1471x/1747540.
[24] Zhu, Yanjie, Peng, Xi, Wu, Yin, Wu, Ed X, Ying, Leslie, Liu, Xin, Zheng, Hairong, Liang, Dong. Direct diffusion tensor estimation using a model-based method with spatial and parametric constraints. Medical Physics[J]. 2017, 44(2): 570-580, https://www.webofscience.com/wos/woscc/full-record/WOS:000397401800023.
[25] Jiang, Ke, Zhu, Yanjie, Jia, Sen, Wu, Yin, Liu, Xin, Chung, YiuCho. Fast T1 mapping of the brain at high field using Look-Locker and. MAGNETIC RESONANCE IMAGING[J]. 2017, 36: 49-55, https://www.webofscience.com/wos/woscc/full-record/WOS:000393536100008.
[26] 江克, 钟耀祖, 吴垠, 朱燕杰. 大脑快速T1图谱成像研究. 集成技术[J]. 2016, 22-26, http://lib.cqvip.com/Qikan/Article/Detail?id=669659752.
[27] Wu, Yin, Kim, Jinsuh, Chan, SukTak, Zhou, Iris Yuwen, Guo, Yingkun, Igarashi, Takahiro, Zheng, Hairong, Guo, Gang, Sun, Phillip Zhe. Comparison of image sensitivity between conventional tensor-based and fast diffusion kurtosis imaging protocols in a rodent model of acute ischemic stroke. NMR IN BIOMEDICINE[J]. 2016, 29(5): 625-630, https://www.webofscience.com/wos/woscc/full-record/WOS:000374495900010.
[28] Yang Shasha, Wu Yin, IEEE. Investigation of the performance of variable-density Z-spectrum acquisition scheme in MR chemical exchange saturation transfer effect quantification. 2015 37TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)null. 2015, 7929-7932, [29] Kim, Jinsuh, Wu, Yin, Guo, Yingkun, Zheng, Hairong, Sun, Phillip Zhe. A review of optimization and quantification techniques for chemical exchange saturation transfer MRI toward sensitive in vivo imaging. CONTRAST MEDIA & MOLECULAR IMAGING[J]. 2015, 10(3): 163-178, https://www.webofscience.com/wos/woscc/full-record/WOS:000356361800001.
[30] Wu, Yin, Jiang, Ke, Zhang, Na, Gao, Yinzhu, Chen, Yucheng, Zheng, Hairong, Liu, Xin, Chung, YiuCho. Efficient Method for Analyzing MR Real-Time Cines: Toward Accurate Quantification of Left Ventricular Function. JOURNAL OF MAGNETIC RESONANCE IMAGING[J]. 2015, 42(4): 972-980, https://www.webofscience.com/wos/woscc/full-record/WOS:000363281500012.
[31] 吴垠. Importance of saturation power optimization in improving the estimation accuracy of chemical exchange rates with the omega plot: a simulation study. 2015PROCEEDINGSOFINTERNATIONALSOCIETYOFMAGNETICRESONANCEINMEDICINE. 2015, [32] 杨帆, 何艳, 张洁, 吴垠. 实时心脏磁共振成像左心室功能分析研究. 生物医学工程学杂志[J]. 2015, 32(6): 1279-1283, https://d.wanfangdata.com.cn/periodical/swyxgcx201506021.
[33] 吴垠. An efficient algorithm for volumetric measurement of left ventricle using real time cines. 2014 Proceedings of International Society of Magnetic Resonance in Medicine. 2014, [34] 吴垠. Importance of high temporal resolution in peak flow velocity quantification by phase-contrast imaging. 2014 Proceedings of International Society of Magnetic Resonance in Medicine. 2014, [35] 吴垠. A robust and fast SSFP cine for the evaluation of LV function at 3T. 2014 Proceedings of International Society of Magnetic Resonance in Medicine. 2014, [36] Wu, Yin, Zhu, YanJie, Tang, QiuYang, Zou, Chao, Liu, Wei, Dai, RuiBin, Liu, Xin, Wu, Ed X, Ying, Leslie, Liang, Dong. Accelerated MR Diffusion Tensor Imaging Using Distributed Compressed Sensing. MAGNETIC RESONANCE IN MEDICINE[J]. 2014, 71(2): 763-772, http://dx.doi.org/10.1002/mrm.24721.
[37] 吴垠. An efficient approach for analysis of real-time cine for LV function quantification. 2013 Proceedings of International Society of Magnetic Resonance in Medicine. 2013, [38] Sun, Phillip Zhe, Lu, Jie, Wu, Yin, Xiao, Gang, Wu, Renhua. Evaluation of the dependence of CEST-EPI measurement on repetition time, RF irradiation duty cycle and imaging flip angle for enhanced pH sensitivity. PHYSICS IN MEDICINE AND BIOLOGY[J]. 2013, 58(17): N229-N240, https://www.webofscience.com/wos/woscc/full-record/WOS:000323517700001.
[39] Wu, Yin, Zou, Chao, Liu, Wei, Liao, Weiqi, Yang, Wei, Porter, David A, Liu, Xin, Wu, Ed X. Effect of B-value in revealing postinfarct myocardial microstructural remodeling using MR diffusion tensor imaging. MAGNETIC RESONANCE IMAGING[J]. 2013, 31(6): 847-856, http://dx.doi.org/10.1016/j.mri.2013.02.010.
[40] 吴垠. Preliminary MR DTI study of age-related regeneration process of skeletal muscle with ischemia injury. 2013 Proceedings of International Society of Magnetic Resonance in Medicine. 2013, [41] 周维林, 江克, 钟耀祖, 吴垠. 心脏实时电影成像数据处理方法研究. 集成技术[J]. 2013, 30-33, http://lib.cqvip.com/Qikan/Article/Detail?id=74677473504849514853484854.
[42] Wu Yin, Yang Fan, Chung YiuCho. Robust and fast SSFP for the evaluation of LV function at 3T. JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE[J]. 2013, 15(Suppl 1): http://dx.doi.org/10.1186/1532-429X-15-S1-O52.
[43] 吴垠. Feasibility study of fast diffusion tensor imaging based on distributed compressed sensing.. 19th ISMRM Annual Meeting Exhibition. 2012, [44] 吴垠. Effect of b-value on DTI sensitivity in revealing myocardial structure degradation in rabbit models with acute myocardium infarction. 19th ISMRM Annual Meeting Exhibition. 2012, [45] 吴垠. Biexponential diffusion tensor analysis of myocardial structural alteration in rabbit models with myocardium infarction. 19th ISMRM Annual Meeting Exhibition. 2012, [46] Wu, Yin, Zhang, LiJuan, Zou, Chao, Tse, HungFat, Wu, Ed X. Transmural Heterogeneity of Left Ventricular Myocardium Remodeling in Postinfarct Porcine Model Revealed by MR Diffusion Tensor Imaging. JOURNAL OF MAGNETIC RESONANCE IMAGING[J]. 2011, 34(1): 43-49, https://www.webofscience.com/wos/woscc/full-record/WOS:000292421800005.
[47] 吴垠. MR diffusion tensor investigation of transmural heterogeneity of myocardium structural remodeling in postinfarct porcine model. 2011 Proceedings of International Society of Magnetic Resonance in Medicine. 2011, [48] Cheung, Jerry S, Au, WingYan, Ha, ShauYin, Kim, Daniel, Jensen, Jens H, Zhou, Iris Y, Cheung, Matthew M, Wu, Yin, Guo, Hua, Khong, PekLan, Brown, Truman R, Brittenham, Gary M, Wu, Ed X. Reduced Transverse Relaxation Rate (RR2) for Improved Sensitivity in Monitoring Myocardial Iron in Thalassemia. JOURNAL OF MAGNETIC RESONANCE IMAGING[J]. 2011, 33(6): 1510-1516, https://www.webofscience.com/wos/woscc/full-record/WOS:000291267700028.
[49] 吴垠. Impact of b-value on DTI indices of left ventricular porcine myocardium: a preliminary study. 2011 Proceedings of International Society of Magnetic Resonance in Medicine. 2011, [50] Zhang, Rongxin, Zhang, Yuan Yuan, Huang, Xiao R, Wu, Yin, Chung, Arthur C K, Wu, Ed Xuekui, Szalai, Alexander J, Wong, Benjamin C Y, Lau, ChuPak, Lan, Hui Y. C-Reactive Protein Promotes Cardiac Fibrosis and Inflammation in Angiotensin II-Induced Hypertensive Cardiac Disease. HYPERTENSION[J]. 2010, 55(4): 953-U265, https://www.webofscience.com/wos/woscc/full-record/WOS:000275701600025.
[51] Liao, SongYan, Siu, ChungWah, Liu, Yuan, Zhang, Yuelin, Chan, WingSze, Wu, Ed X, Wu, Yin, Nicholls, John M, Li, Ronald A, Benser, Michael E. Attenuation of Left Ventricular Adverse Remodeling With Epicardial Patching After Myocardial Infarction. JOURNAL OF CARDIAC FAILURE[J]. 2010, 16(7): 590-598, http://dx.doi.org/10.1016/j.cardfail.2010.02.007.
[52] Wu, Yin, Wu, Ed X. MR Study of Postnatal Development of Myocardial Structure and Left Ventricular Function. JOURNAL OF MAGNETIC RESONANCE IMAGING[J]. 2009, 30(1): 47-53, https://www.webofscience.com/wos/woscc/full-record/WOS:000267452600007.
[53] Wu, Yin, Chan, Carmen W, Nicholls, John M, Liao, Songyan, Tse, HungFat, Wu, Ed X. MR Study of the Effect of Infarct Size and Location on Left Ventricular Functional and Microstructural Alterations in Porcine Models. JOURNAL OF MAGNETIC RESONANCE IMAGING[J]. 2009, 29(2): 305-312, https://www.webofscience.com/wos/woscc/full-record/WOS:000262819300008.
[54] 吴垠. MR study of the effect of infarct size and location on left ventricular functional and structural remodeling in porcine models. Journal of Magnetic Resonance Imaging. 2009, [55] Liao, SongYan, Siu, ChungWah, Lai, WingHon, Au, KaWing, Liu, Yuan, Wu, Ed, Wu, Yin, Yip, Pandora M, Li, Ronald, Lau, ChuPak, Tse, HungFat. Pro-arrhythmic Risk of Embryonic Stem Cell-Derived Cardiomyocyte Transplantation in Infarcted Myocardium. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY[J]. 2009, 53(10): A310-A310, https://www.webofscience.com/wos/woscc/full-record/WOS:000263864201285.
[56] Zhang, Rongxin, Zhang, Yuanyuan, Huang, Xiao R, Wu, Yin, Szalai, Alexander J, Wong, B C, Lau, C P, Wu, Ed X, Lan, Hui Y. C-Reactive Protein Promotes Cardiac Inflammation and Fibrosis in Angiotensin II-Induced Hypertensive Cardiovascular Diseases. CIRCULATION RESEARCHnull. 2009, 105(7): E17-E17, https://www.webofscience.com/wos/woscc/full-record/WOS:000270150800050.
[57] Chow, Tracy Y, Cheung, Jerry S, Wu, Yin, Guo, Hua, Chan, Kevin C, Hui, Edward S, Wu, Ed X. Measurement of Common Carotid Artery Lumen Dynamics during the Cardiac Cycle Using Magnetic Resonance TrueFISP Cine Imaging. JOURNAL OF MAGNETIC RESONANCE IMAGING[J]. 2008, 28(6): 1527-1532, https://www.webofscience.com/wos/woscc/full-record/WOS:000261270500028.
[58] 吴垠. Measurement of common carotid artery lumen dynamics during cardiac cycle using MR TrueFISP cine imaging. Journal of Magnetic Resonance Imaging. 2008, [59] Wu, Ed X, Wu, Yin, Tang, Halying, Wang, Jie, Yang, Jian, Ng, Man C, Yang, Edward S, Chan, Cannen W, Zhu, Shuguang, Lau, ChuPak, Tse, HungFat. Study of myocardial fiber pathway using magnetic resonance diffusion tensor imaging. MAGNETIC RESONANCE IMAGING[J]. 2007, 25(7): 1048-1057, http://dx.doi.org/10.1016/j.mri.2006.12.008.
[60] Wu Yin, Wu Ed X, IEEE. In vivo MR coronary artery imaging in mice. 2007ANNUALINTERNATIONALCONFERENCEOFTHEIEEEENGINEERINGINMEDICINEANDBIOLOGYSOCIETYVOLS116null. 2007, 4520-4523, [61] Wu, Ed X, Wu, Yin, Nicholls, John M, Wang, Jie, Liao, Songyan, Zhu, Shuguang, Lau, ChuPak, Tse, HungFat. MR diffusion tensor imaging study of postinfarct myocardium structural remodeling in a porcine model. MAGNETIC RESONANCE IN MEDICINE[J]. 2007, 58(4): 687-695, https://www.webofscience.com/wos/woscc/full-record/WOS:000249849200006.
[62] Wu Yin, Tse HungFat, Wu Ed X, IEEE. Diffusion tensor MRI study of myocardium structural remodeling after infarction in porcine model. 2006 28TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOLS 1-15null. 2006, 3166-+, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000247284703161.
[63] 吴垠. Myocardial fiber length mapping with MR diffusion tensor imaging. Conf Proc IEEE Eng Med Biol Soc.. 2005, [64] Zongwei Xu, Chao Ke, Jie Liu, Shijie Xu, Lujun Han, Yadi Yang, Long Qian, Xin Liu, Hairong Zheng, Xiaofei Lv, Yin Wu. Diagnostic performance between MR amide proton transfer (APT) and diffusion kurtosis imaging (DKI) in glioma grading and IDH mutation status prediction at 3 Tesla. EUROPEAN JOURNAL OF RADIOLOGY. http://dx.doi.org/10.1016/j.ejrad.2020.109466.
[65] Investigation of muscle degeneration process in young rats with ischemia injury using MR diffusion tensor imaging. http://ir.siat.ac.cn:8080/handle/172644/4926.
[66] MR investigation of the coupling between myocardial fiber architecture and cardiac contraction. http://ir.siat.ac.cn:8080/handle/172644/2583.
[67] Statistical evaluation of fitting models of diffusion tensor imaging in characterizing normal porcine myocardium. http://ir.siat.ac.cn:8080/handle/172644/3517.
发表著作
(1) 磁共振功能成像及临床应用, Functional Magnetic Resonance Imaging and Clinical Applications, 人民军医出版社, 2012-03, 第 1 作者
(2) Preclinical MRI of the kidney, Humana Press, 2021-02, 第 2 作者

科研活动

   
科研项目
( 1 ) 缺血存活心肌定量检测的磁共振化学交换饱和转移成像研究【国家自然科学基金面上项目】, 负责人, 国家任务, 2016-01--2019-12
( 2 ) 48 通道头颈联合血管线圈的研制【科技部重点研发计划】, 负责人, 国家任务, 2016-07--2018-09
( 3 ) 缺血缺氧脑损伤的磁共振pH定量成像研究【国家自然科学基金面上项目】, 负责人, 国家任务, 2019-01--2022-12
( 4 ) 磁共振pH定量成像无创监测胶质瘤乏氧微环境的关键技术研究【国家自然科学基金重大研究计划培育项目】, 负责人, 国家任务, 2019-01--2021-12
( 5 ) 高密度柔性磁共振成像探测阵列的研发【科技部重点研发计划】, 负责人, 国家任务, 2022-11--2025-10
( 6 ) 基于蛋白水平评价胶质瘤异质性的磁共振三维APT定量成像方法研究【国家自然科学基金面上项目】, 负责人, 国家任务, 2023-01--2026-12
( 7 ) 磁共振肿瘤能量代谢分子信息可视化新方法及其用于胶质瘤诊疗研究【国家自然科学基金重大研究计划重点项目】, 负责人, 国家任务, 2023-01--2026-12
( 8 ) 超高场磁共振代谢成像关键技术研究【深圳市优秀科技创新人才培养项目(杰出青年基础研究)】, 负责人, 地方任务, 2023-04--2028-04
参与会议
(1)MR chemical exchange saturation transfer study of myocardium creatine dynamic change in an acute infarct porcine model   2022-05-07
(2)Fast and accurate creatine chemical exchange saturation transfer imaging with quasi-steady-state (QUASS) post-processing algorithm at 3T   2022-05-07
(3)Breast amide proton transfer imaging at 3T: diagnostic performance and correlation with pathologic characteristics   2022-05-07
(4)Quantification of the impact of Gadolinium agent on amide-proton-transfer weighted MRI: an ex vivo and in vivo study   2022-05-07
(5)Quasi-steady-state reconstruction provides fast equilibrium APT imaging of brain tumor patients at 3T   2022-05-07
(6)Feasibility of creatine chemical exchange saturation transfer (CEST) imaging in evaluating cardiac dysfunction in acute infarct heart   2021-05-15
(7)Preliminary demonstration of in vivo quasi-steady-state (QUASS) CEST for robust quantification of tumor MT and APT effects by correction of saturation time and relaxation delay   2021-05-15
(8)Assessment of acquisition strategies of CEST MR fingerprinting pH imaging using Cramer-Rao Bound algorithm   2021-05-15
(9)Prediction of prognostic characteristics in glioma patients using amide proton transfer imaging at 3 Tesla   2020-08-08
(10)Discrimination between lower-grade glioma and glioblastoma with amide proton transfer and diffusion kurtosis imaging at 3 Tesla   2020-08-08
(11)Investigation of the reliability in pH quantification with MR chemical exchange saturation transfer (CEST) power ratiometric imaging at 3 Tesla   2020-08-08
(12)Assessment of postinfarct myocardium metabolic degradation with amide proton transfer magnetic resonance imaging at 3 Tesla   2019-05-11
(13)Improved tumor characterization with direct saturation corrected (DISC) amide proton transfer (APT) MRI in glioma patients   2019-05-11
(14)Differentiation between glioma recurrence and treatment effects using DWI, ASL, proton MRS and amide proton transfer (APT) imaging at 3 Tesla   2019-05-11

合作情况

   
项目协作单位

  • Harvard Medical School and Massachusetts General Hospital

  • Emory University

  • University of Hong Kong

  • 中山大学肿瘤防治中心

  • 四川大学华西医院

  • 上海长征医院

  • 复旦大学附属华山医院

  • 华中科技大学附属同济医院

  • 中国医学科学院肿瘤医院深圳医院

  • 北京大学深圳医院

  • 深圳市儿童医院

指导学生

已指导学生

杨沙沙  硕士研究生  083100-生物医学工程  

申浩  硕士研究生  085404-计算机技术  

李文博  硕士研究生  085404-计算机技术  

现指导学生

朱静珂  硕士研究生  083100-生物医学工程  

联合培养学生

2024 罗琦丹(重庆理工大学)

2024 钟天兆(南方科技大学-深圳理工大学)

2024 崔梓浩(深圳大学)

2024 唐昊(深圳大学)

2023 余海丰(东北大学)

2023 杨欢欢(南方科技大学-深圳理工大学)

2023 殷鹏(东北大学)

2022 谢嘉慧(南方科技大学-深圳理工大学)

2022 吴绮婷(深圳大学)

2022 巩鹏程(重庆理工大学)

2021 赵佳磊(南方科技大学-深圳理工大学)

2021 匡俊峰(南方科技大学-深圳理工大学)

2020 宋凯昕(东北大学)

2019 刘洁(上海交通大学)

2018 韦紫君(中国科学院大学) 

2018 刁凯悦(四川大学) 

2017 容豫(四川大学) 

2015 王小天(东北大学) 

2014 周维林(东北大学) 

2013 安一硕(吉林大学) 

2013 唐秋阳(吉林大学) 

2012 刘伟(哈尔滨工业大学) 

2011 刘畅(哈尔滨工业大学)

博士后培养

2024-           刘付童玲

2023-           李锡涛

2023-           李佳明

2023-           陈娇

2022-           张瑞芬

2022-2024   布阿结尔古丽 麦麦提

2019-2021   刘洁