Asymmetric Catalysis

1. Asymmetric Hydrogenation of Heteroaromatic Compounds;

2. Pd-catalyzed Asymmetric Hydrogenation;

3. Asymmetrichydrogenolysis.

1996-1999 Ph.D. Degree from Shanghai Institute of Organic Chemistry

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1999-2002  Post-doc fellow at Pennsylvania State University

2002-          Full professor, Dalian Institute of Chemical Physics

2013-          Director, Laboratory of  Fine Chemistry

​2012-         Chinese Chemical Science Award  for Young Chemist;

2012-         National Science Foundation for Distinguished Young Scholars;
2013-         The State Council Special Allowance.

已指导学生

汪游清  博士研究生  070303-有机化学  

曾伟  博士研究生  070303-有机化学  

杨鹏宇  硕士研究生  070303-有机化学  

刘启宾  博士研究生  070303-有机化学  

赵玉军  硕士研究生  070303-有机化学  

陈国英  硕士研究生  070303-有机化学  

王小兵  博士研究生  070303-有机化学  

王大伟  博士研究生  070303-有机化学  

王躲生  博士研究生  070303-有机化学  

余长斌  博士研究生  070303-有机化学  

陈庆安  博士研究生  070303-有机化学  

高凯  博士研究生  070303-有机化学  

叶智识  博士研究生  070303-有机化学  

段英  博士研究生  070303-有机化学  

蔡先锋  博士研究生  070303-有机化学  

郭冉柠  博士研究生  070303-有机化学  

任慧芳  博士研究生  070303-有机化学  

黄文学  博士研究生  070303-有机化学  

陈章培  博士研究生  070303-有机化学  

吴波  博士研究生  070303-有机化学  

高翔  博士研究生  070303-有机化学  

宋波  博士研究生  070303-有机化学  

姬悦  博士研究生  070303-有机化学  

冯广收  博士研究生  070303-有机化学  

胡书博  博士研究生  070303-有机化学  

严忠  博士研究生  070303-有机化学  

王杰  博士研究生  070303-有机化学  

谢焕平  博士研究生  070303-有机化学  

沈宏强  博士研究生  070303-有机化学  

翟小勇  博士研究生  070303-有机化学  

现指导学生

王新维  博士研究生  070303-有机化学  

朱周豪  博士研究生  070303-有机化学  

赵洋  博士研究生  070303-有机化学  

牛童  硕士研究生  070303-有机化学  

王晓清  博士研究生  070303-有机化学  

丁艺璇  博士研究生  070303-有机化学  

刘正  硕士研究生  070303-有机化学  

谢庆贤  硕士研究生  070303-有机化学  

白雨晴  博士研究生  070303-有机化学  

刘丽霞  博士研究生  070303-有机化学  

1. Zhou-Hao Zhu, Yi-Xuan Ding, Bo Wu and Yong-Gui Zhou.* Design and Synthesis of Chiral and Regenerable [2.2]Paracyclophane-Based NAD(P)H Models and Application in Biomi- metic Reduction of Flavonoids. Chem. Sci. 2020, 11, 10220-10224.

2. Jie Wang, Zi-Biao Zhao, Yanan Zhao, Gen Luo, Zhou-Hao Zhu, Yi Luo* and Yong-Gui Zhou.* Chiral and Regenerable NAD(P)H Models Enabled Biomimetic Asymmetric Reduction: Design, Synthesis, Scope, and Mechanistic Studies. J. Org. Chem. 2020, 85, 2355-2368.

3. Yuan He, Jiang Lou, Ping Wu, Yong-Gui Zhou* and Zhengkun Yu.* Copper-Catalyzed Annulative Coupling of S,S-Disubstituted Enones with Diazo Compounds to Access Highly Functionalized Thiophene Derivatives. J. Org. Chem. 2020, 85, 1044-1053.

4. Ping Wu, Yuan He, Hongmei Wang,* Yong-Gui Zhou* and Zhengkun Yu.* Copper(II)-Catalyzed C−H Nitrogenation/Annulation Cascade of Ketene N,S-Acetals with Aryldiazonium Salts: A Direct Access to N2-Substituted Triazole and Triazine Derivatives. Org. Lett. 2020, 22, 310-315.

5. Chang-Bin Yu, Heng-Ding Wang, Bo Song, Hong-Qiang Shen, Hong-Jun Fan* and Yong-Gui Zhou.* Reversal of Diastereoselectivity in Palladium-Arene Interaction Directed Hydrogenative Desymmetrization of 1,3-Diketones. Sci. China Chem. 2020, 63, 215-221.

6. Jie Wang, Zhou-Hao Zhu, Mu-Wang Chen, Qing-An Chen and Yong-Gui Zhou.* Catalytic Biomimetic Asymmetric Reduction of Alkenes and Imines Enabled by Chiral and Regenerable NAD(P)H Models. Angew. Chem. Int. Ed. 2019, 58, 1813-1817.

7. Guang-Shou Feng, Mu-Wang Chen, Lei Shi* and Yong-Gui Zhou.* Facile Synthesis of Chiral Cyclic Ureas through Hydrogenation of 2-Hydroxypyrimidine/Pyrimidin-2(1H)-one Tautomers. Angew. Chem. Int. Ed. 2018, 57, 5853-5857.

8. Bo Wu, Zhaoyuan Yu, Xiang Gao, Yu Lan* and Yong-Gui Zhou.* Regioselective α-Addition of Deconjugated Butenolides: Enantioselective Synthesis of Dihydrocoumarins. Angew. Chem. Int. Ed. 2017, 56, 4006-4010.

9. Jie Wang, Mu-Wang Chen, Yue Ji, Shu-Bo Hu and Yong-Gui Zhou.* Kinetic Resolution of Axially Chiral 5- or 8-Substituted Quinolines via Asymmetric Transfer Hydrogenation. J. Am. Chem. Soc. 2016, 138, 10413-10416.

10. Xiang Gao, Bo Wu, Wen-Xue Huang, Mu-Wang Chen, and Yong-Gui Zhou.* Enantioselective Palladium-Catalyzed C-H Functionalization of Indoles Using an Axially Chiral 2,2’-Bipyridine Ligand. Angew. Chem. Int. Ed. 2015, 54, 11956-11960.

11. Yue Ji, Lei Shi,* Mu-Wang Chen, Guang-Shou Feng, and Yong-Gui Zhou.* Concise Redox Deracemization of Secondary and Tertiary Amines with a Tetrahydroisoquinoline Core via a Nonenzymatic Process. J. Am. Chem. Soc. 2015, 137, 10496-10499.

12.  Chang-Bin Yu, Yong-Gui Zhou.* Palladium-Catalyzed Asymmetric Hydrogenolysis of N-Sulfonyl Aminoalcohols via Achiral EnesulfonamideIntermediates. Angew. Chem. Int. Ed. 2013, 52, 13365-13368.

13. Zhi-Shi Ye, Ran-Ning Guo, Xian-Feng Cai, Mu-Wang Chen, Lei Shi, Yong-Gui Zhou.* EnantioselectiveIridium-Catalyzed Hydrogenation of 1- and 3-Substituted Isoquinolinium Salts. Angew. Chem. Int. Ed. 2013, 52, 3685-3689.

14. Zhi-Shi Ye, Mu-Wang Chen, Qing-An Chen, Lei Shi, Ying Duan, Yong-Gui Zhou.* Ir-Catalyzed Asymmetric Hydrogenation of Pyridinium Salts. Angew. Chem. Int. Ed. 2012, 51, 10181-10184.

15. Lei Shi, Zhi-Shi Ye, Liang-Liang Cao, Ran-Ning Guo, Yue Hu, Yong-Gui Zhou.* EnantioselectiveIridium-Catalyzed Hydrogenation of 3,4-Disubstituted Isoquinolines. Angew. Chem. Int. Ed. 2012, 51, 8286-8289.

16. Qing-An Chen, Kai Gao, Ying Duan, Zhi-Shi Ye, Lei Shi, Yan Yang, Yong-Gui Zhou.* Dihydrophenanthridine: A New and Easily Regenerable NAD(P)H Model for BiomimeticAsymmetric Hydrogenation. J. Am. Chem. Soc. 2012, 134, 2442-2448.