基本信息

张扬 男 南海海洋研究所
电子邮件:yzhang@scsio.ac.cn
通信地址:广州市新港西路164号
邮政编码:510301
电子邮件:yzhang@scsio.ac.cn
通信地址:广州市新港西路164号
邮政编码:510301
研究领域
1. 贝类分子免疫学
2.贝类功能基因组学
2.贝类功能基因组学
招生信息
招生专业
070703-海洋生物学
招生方向
贝类分子免疫学
贝类功能基因组学
贝类功能基因组学
教育背景
2003-09--2009-06 中山大学 博士
1999-09--2003-06 河南师范大学 学士
1999-09--2003-06 河南师范大学 学士
工作经历
工作简历
2011-12--2014-01 中国科学院南海海洋研究所 副研究员
2009-07--2011-12 中国科学院南海海洋研究所 助理研究员
2009-07--2011-12 中国科学院南海海洋研究所 助理研究员
专利与奖励
奖励信息
(1) 中科院青年促进会,院级级,2013
(2) 广州市珠江科技新星,市地级,2012
(2) 广州市珠江科技新星,市地级,2012
出版信息
发表论文
[1] 赵泽慧, 张爱娇, 杨雨澄, 毛帆, 肖述, 李军, 张扬, 向志明, 喻子牛. 香港牡蛎(Crassostrea hongkongensis)新型凝集素ChPerlucin的基因克隆与功能研究. 热带海洋学报[J]. 2022, 第 7 作者41(1): 42-51, https://www.jto.ac.cn/CN/10.11978/2021029.
[2] Genomics Proteomics Bioinformatics. 2022, 第 1 作者
[3] 刘坤娜, 毛帆, 张翔宇, 林玥, 张扬, 喻子牛. Thraustochytrium caudivorum--一种香港牡蛎新型原生生物寄生虫. 海洋通报[J]. 2021, 第 5 作者40(1): 53-61, http://lib.cqvip.com/Qikan/Article/Detail?id=7104547072.
[4] Ma, Haitao, Zhang, Yuehuan, Xiang, Zhiming, Zhang, Yang, Qin, Yanping, Yu, Ziniu. Development of tri-nucleotide microsatellite markers from Crassostrea hongkongensis using enriched genomic libraries and cross-species amplification in two closely related species. AQUACULTURE REPORTS[J]. 2021, 第 4 作者19: http://dx.doi.org/10.1016/j.aqrep.2021.100592.
[5] Wang, Sufang, Huang, Yiyi, Liu, Si, Lin, Zhihua, Zhang, Yang, Bao, Yongbo. Hemoglobins from Scapharca subcrenata (Bivalvia: Arcidae) likely play an bactericidal role through their peroxidase activity. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY[J]. 2021, 第 5 作者 通讯作者 253: http://dx.doi.org/10.1016/j.cbpb.2020.110545.
[6] nature ecology and evolution. 2021, 第 1 作者
[7] molecular biology evolution. 2021, 第 4 作者
[8] Sun, Bo, Zhang, Yang, Zhou, Qiming, Gao, Duo. Street-Scale Analysis of Population Exposure to Light Pollution Based on Remote Sensing and Mobile Big Data-Shenzhen City as a Case. SENSORS[J]. 2020, 第 2 作者20(9): https://doaj.org/article/7ead8f5c43c34b7ca1f5b1b0ec956257.
[9] Mao, Fan, Wong, NaiKei, Lin, Yue, Zhang, Xiangyu, Liu, Kunna, Huang, Minwei, Xu, Duo, Xiang, Zhiming, Li, Jun, Zhang, Yang, Yu, Ziniu. Transcriptomic Evidence Reveals the Molecular Basis for Functional Differentiation of Hemocytes in a Marine Invertebrate,Crassostrea gigas. FRONTIERS IN IMMUNOLOGY[J]. 2020, 第 10 作者 通讯作者 11: https://doaj.org/article/0b45f68104244f189bfc391556f0725c.
[10] Zhang, XiaoFan, Chen, Ting, Yan, Aifen, Xiao, Jia, Xie, YongLi, Yuan, Jing, Chen, Pin, Wong, Anderson OnLam, Zhang, Yang, Wong, NaiKei. Poly(I:C) Challenge Alters Brain Expression of Oligodendroglia-Related Genes of Adult Progeny in a Mouse Model of Maternal Immune Activation. FRONTIERS IN MOLECULAR NEUROSCIENCE[J]. 2020, 第 9 作者 通讯作者 13: https://doaj.org/article/068eeace01334a3fac62d519ede05e66.
[11] Zhou, Yinyin, Liu, Kunna, Li, Xingyou, Qin, Yanpin, Zhang, Yuehuan, Zhang, Yang, Xiang, Zhiming, Ma, Haitao, Li, Jun, Yu, Ziniu. Molluscan Beclin-1 is involved in the innate immune response by regulating the autophagosomes formation in Crassostrea hongkongensis. AQUACULTURE REPORTS[J]. 2020, 第 6 作者18: http://dx.doi.org/10.1016/j.aqrep.2020.100541.
[12] Lin, Yue, Mao, Fan, Wong, NaiKei, Zhang, Xiangyu, Liu, Kunna, Huang, Minwei, Ma, Haitao, Xiang, Zhiming, Li, Jun, Xiao, Shu, Zhang, Yang, Yu, Ziniu. Phagocyte Transcriptomic Analysis Reveals Focal Adhesion Kinase (FAK) and Heparan Sulfate Proteoglycans (HSPGs) as Major Regulators in Anti-bacterial Defense of Crassostrea hongkongensis. FRONTIERS IN IMMUNOLOGY[J]. 2020, 第 11 作者 通讯作者 11: https://doaj.org/article/77ef30a08ceb45d89ff6c99d67fcb4fd.
[13] Wang, Bing, Zhang, Yang. An immune-relevant signature of nine genes as a prognostic biomarker in patients with gastric carcinoma. OPEN MEDICINE[J]. 2020, 第 2 作者 通讯作者 15(1): 850-859, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718618/.
[14] Cheng, Zhao, Luo, Yunya, Zhang, Yang, Wang, Yewei, Chen, Yi, Xu, Yunxiao, Peng, Honling, Zhang, Guangsen. A novel NAP1L4/NUTM1 fusion arising from translocation t(11;15)(p15;q12) in a myeloid neoplasm with eosinophilia and rearrangement of PDGFRA highlights an unusual clinical feature and therapeutic reaction. ANNALS OF HEMATOLOGY[J]. 2020, 第 3 作者99(7): 1561-1564, http://dx.doi.org/10.1007/s00277-020-04000-x.
[15] Lin, Yue, Mao, Fan, Zhang, Xiangyu, Xu, Duo, He, Zhiying, Li, Jun, Xiang, Zhiming, Zhang, Yang, Yu, Ziniu. TRAF6 suppresses the apoptosis of hemocytes by activating pellino in Crassostrea hongkongensis. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY[J]. 2020, 第 8 作者 通讯作者 103: 103501, http://dx.doi.org/10.1016/j.dci.2019.103501.
[16] Mu, Huawei, Ke, Shengwei, Zhang, Duo, Zhang, Yanjie, Song, Xiaoyuan, Yu, Ziniu, Zhang, Yang, Qiu, JianWen. The Sperm Proteome of the OysterCrassostrea hongkongensis. PROTEOMICS. 2020, 第 7 作者20(19-20): https://www.webofscience.com/wos/woscc/full-record/WOS:000574839100001.
[17] Li, Jun, Zhou, Yinyin, Zhou, Zihua, Lin, Chuanxu, Wei, Jinkuan, Qin, Yanpin, Xiang, Zhiming, Ma, Haitao, Zhang, Yang, Zhang, Yuehuan, Yu, Ziniu. Comparative transcriptome analysis of three gonadal development stages reveals potential genes involved in gametogenesis of the fluted giant clam (Tridacna squamosa). BMC GENOMICS[J]. 2020, 第 9 作者21(1): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720611/.
[18] Mao, Fan, Liu, Kunna, Bao, Yongbo, Lin, Yue, Zhang, Xiangyu, Xu, Duo, Xiang, Zhiming, Li, Jun, Zhang, Yang, Yu, Ziniu. Opsonic character of the plasma proteins in phagocytosis-dependent host response to bacterial infection in a marine invertebrate, Crassostrea gigas. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY[J]. 2020, 第 9 作者 通讯作者 106: http://dx.doi.org/10.1016/j.dci.2019.103596.
[19] Duo Xu, Zehui Zhao, Zihua Zhou, Yue Lin, Xiangyu Zhang, Yang Zhang, Yuehuan Zhang, Jun Li, Fan Mao, Shu Xiao, Haitao Ma, Xiang Zhiming, Ziniu Yu. Mechanistic molecular responses of the giant clam Tridacna crocea to Vibrio coralliilyticus challenge. PLOSONE[J]. 2020, 第 6 作者15(4): https://doaj.org/article/23b0d646b1564862ba6bc79ac5a7d973.
[20] Ma, Haitao, Xiang, Zhiming, Zhang, Yang, Li, Jun, Qin, Yanping, Zhang, Yuehuan, Yu, Ziniu. First report of the mitochondrial DNA sequences of the giant clam, Tridacna gigas (Tridacnidae Tridacna). MITOCHONDRIAL DNA PART B-RESOURCES[J]. 2020, 第 3 作者5(3): 3614-3615, http://dx.doi.org/10.1080/23802359.2020.1830729.
[21] Mao, Fan, Mu, Huawei, Wong, NaiKei, Liu, Kunna, Song, Jingchen, Qiu, Jianwen, Lin, Yue, Zhang, Xiangyu, Xu, Duo, Xiang, Zhiming, Li, Jun, Zhang, Yang, Yu, Ziniu. Hemocyte phagosomal proteome is dynamically shaped by cytoskeleton remodeling and interorganellar communication with endoplasmic reticulum during phagocytosis in a marine invertebrate, Crassostrea gigas. SCIENTIFIC REPORTS[J]. 2020, 第 12 作者 通讯作者 10(1): http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000537155000007.
[22] Qin, Yanping, Zhang, Yuehuan, Mo, Riguan, Zhang, Yang, Li, Jun, Zhou, Yingli, Ma, Haitao, Xiao, Shu, Yu, Ziniu. Influence of ploidy and environment on grow-out traits of diploid and triploid Hong Kong oysters Crassostrea hongkongensis in southern China. AQUACULTURE[J]. 2019, 第 4 作者507: 108-118, http://dx.doi.org/10.1016/j.aquaculture.2019.04.017.
[23] Zhang, Yang, Yu, Ziniu. The transcriptome reveals the molecular mechanisms underlying hemocytes differentiation in the oyster. FISH & SHELLFISH IMMUNOLOGY[J]. 2019, 第 1 作者91: 439-439, http://dx.doi.org/10.1016/j.fsi.2019.04.202.
[24] Yu, Mingjia, Zheng, Lin, Wang, Xiaobo, Wu, Minfu, Qi, Ming, Fu, Wandong, Zhang, Yang. Comparative transcriptomic analysis of surf clams (Paphia undulate) infected with two strains of Vibrio spp. reveals the identity of key immune genes involved in host defense. BMC GENOMICS[J]. 2019, 第 7 作者 通讯作者 20(1): http://dx.doi.org/10.1186/s12864-019-6351-4.
[25] Guo, Ya, Zhang, Yang, Zhang, Shu Juan, Ma, Yi Nan, He, Yun. Comprehensive analysis of key genes and microRNAs in radioresistant nasopharyngeal carcinoma. BMC MEDICAL GENOMICS[J]. 2019, 第 2 作者12(1): http://dx.doi.org/10.1186/s12920-019-0507-6.
[26] Yang Zhang, Ziniu Yu. The transcriptome reveals the molecular mechanisms underlying hemocytes differentiation in the oyster. FISHANDSHELLFISHIMMUNOLOGY. 2019, 第 1 作者91: 439-439, http://dx.doi.org/10.1016/j.fsi.2019.04.202.
[27] Wenzhe Yan, Ji Li, Yang Zhang, Yafei Yin, Zhao Cheng, Jiayi Wang, Guoyu Hu, Sufang Liu, Yewei Wang, Yunxiao Xu, Hongling Peng, Guangsen Zhang. RNF8 is responsible for ATRA resistance in variant acute promyelocytic leukemia with GTF2I/RARA fusion, and inhibition of the ubiquitin–proteasome pathway contributes to the reversion of ATRA resistance. CANCER CELL INTERNATIONAL[J]. 2019, 第 3 作者19(1): 1-13, https://doaj.org/article/aae3d337e416402da1cb6a4febe231ec.
[28] Zhiying He, Fan Mao, Yue Lin, Jun Li, Xiangyu Zhang, Yuehuan Zhang, Zhiming Xiang, Zohaib Noor, Yang Zhang, Ziniu Yu. Molecular characteristics of AMPK and its role in regulating the phagocytosis of oyster hemocytes. FISH AND SHELLFISH IMMUNOLOGY. 2019, 第 9 作者93: 416-427, http://dx.doi.org/10.1016/j.fsi.2019.07.075.
[29] Fan Mao, Yue Lin, Zhiying He, Jun Li, Zhiming Xiang, Yang Zhang, Ziniu Yu. Dual roles of cystatin A in the immune defense of the pacific oyster, Crassostrea gigas. FISH AND SHELLFISH IMMUNOLOGY. 2018, 第 6 作者190-197, http://dx.doi.org/10.1016/j.fsi.2018.01.041.
[30] Zhou, Yingli, Mao, Fan, He, Zhiying, Li, Jun, Zhang, Yuehuan, Xiang, Zhiming, Xiao, Shu, Ma, Haitao, Zhang, Yang, Yu, Ziniu. The Molecular Mechanism Underlying Pro-apoptotic Role of Hemocytes Specific Transcriptional Factor Lhx9 in Crassostrea hongkongensis. FRONTIERS IN PHYSIOLOGY[J]. 2018, 第 9 作者 通讯作者 9: https://doaj.org/article/2c9d60a2d34f478e87ba6c3cbddfff8e.
[31] Feng, Chenzhe, Ma, Fang, Hu, Chunhong, Ma, Jinan, Wang, Jingjing, Zhang, Yang, Wu, Fang, Hou, Tao, Jiang, Shun, Wang, Yapeng, Feng, Yeqian. SOX9/miR-130a/CTR1 axis modulates DDP-resistance of cervical cancer cell. CELL CYCLE[J]. 2018, 第 6 作者17(4): 448-458, https://www.webofscience.com/wos/woscc/full-record/WOS:000430498900016.
[32] Mao, Fan, Lin, Yue, He, Zhiying, Li, Jun, Xiang, Zhiming, Zhang, Yang, Yu, Ziniu. Dual roles of cystatin A in the immune defense of the pacific oyster, Crassostrea gigas. FISH & SHELLFISH IMMUNOLOGY[J]. 2018, 第 6 作者 通讯作者 75: 190-197, http://dx.doi.org/10.1016/j.fsi.2018.01.041.
[33] Jun Li, Yuehuan Zhang, Fan Mao, Yue Lin, Shu Xiao, Zhiming Xiang, Haitao Ma, Yang Zhang, Ziniu Yu. The first morphologic and functional characterization of hemocytes in Hong Kong oyster, Crassostrea hongkongensis. FISH AND SHELLFISH IMMUNOLOGY. 2018, 第 8 作者81: 423-429, http://dx.doi.org/10.1016/j.fsi.2018.05.062.
[34] Xiao, Shu, Wong, NaiKei, Li, Jun, Lin, Yue, Zhang, Yuehuan, Ma, Haitao, Mo, Riguan, Zhang, Yang, Yu, Ziniu. Analysis of in situ Transcriptomes Reveals Divergent Adaptive Response to Hyper- and Hypo-Salinity in the Hong Kong Oyster, Crassostrea hongkongensis. FRONTIERS IN PHYSIOLOGY[J]. 2018, 第 8 作者 通讯作者 9: https://doaj.org/article/dcc445d3be8747bc894b763cdecb2b0a.
[35] Zhao, Danyi, Zhang, Yang, Song, Lei. MiR-16-1 Targeted Silences Far Upstream Element Binding Protein 1 to Advance the Chemosensitivity to Adriamycin in Gastric Cancer. PATHOLOGY & ONCOLOGY RESEARCH[J]. 2018, 第 2 作者24(3): 483-488, https://www.webofscience.com/wos/woscc/full-record/WOS:000433372000006.
[36] Dong, Dujuan, Zhang, Yang, Smykal, Vlastimil, Ling, Lin, Raikhel, Alexander S. HR38, an ortholog of NR4A family nuclear receptors, mediates 20-hydroxyecdysone regulation of carbohydrate metabolism during mosquito reproduction. INSECTBIOCHEMISTRYANDMOLECULARBIOLOGY[J]. 2018, 第 2 作者96: 19-26, http://dx.doi.org/10.1016/j.ibmb.2018.02.003.
[37] Fan Mao, Jun Li, Yuehuan Zhang, Zhiming Xiang, Yang Zhang, Ziniu Yu. Molecular cloning and functional analysis of tumor necrosis factor receptor-associated factor 6 (TRAF6) in Crossastrea gigas. FISH AND SHELLFISH IMMUNOLOGY. 2017, 第 5 作者37-45, http://dx.doi.org/10.1016/j.fsi.2017.06.049.
[38] Wang, JiaLin, Saha, Tusar T, Zhang, Yang, Zhang, Changyu, Raikhel, Alexander S. Juvenile hormone and its receptor methoprene-tolerant promote ribosomal biogenesis and vitellogenesis in the Aedes aegypti mosquito. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2017, 第 3 作者292(24): 10306-10315, http://dx.doi.org/10.1074/jbc.M116.761387.
[39] 张跃环, 武祥伟, 秦艳平, 肖述, 马海涛, 李军, 张扬, 喻子牛. 熊本牡蛎多嵴和无嵴品系F3生长性状的连续选择效应. 中国水产科学[J]. 2017, 第 7 作者24(6): 1161-1167, http://lib.cqvip.com/Qikan/Article/Detail?id=7000364771.
[40] Zhang, Yuehuan, Su, Jiaqi, Li, Jun, Zhang, Yang, Xiao, Shu, Yu, Ziniu. Survival and growth of reciprocal crosses between two stocks of the Hong Kong oyster Crassostrea hongkongensis (Lam & Morton, 2003) in southern China. AQUACULTURE RESEARCH[J]. 2017, 第 4 作者48(5): 2344-2354, http://ir.scsio.ac.cn/handle/344004/16269.
[41] Zhang, Yuehuan, Zhang, Yang, Li, Jun, Yu, Ziniu. Morphological and molecular evidence of hybridization events between two congeneric oysters, Crassostrea hongkongensis and C. ariakensis, in southern China. JOURNAL OF MOLLUSCAN STUDIES[J]. 2017, 第 2 作者83: 129-131, http://ir.scsio.ac.cn/handle/344004/16235.
[42] Sun, Jin, Zhang, Yu, Xu, Ting, Zhang, Yang, Mu, Huawei, Zhang, Yanjie, Lan, Yi, Fields, Christopher J, Hui, Jerome Ho Lam, Zhang, Weipeng, Li, Runsheng, Nong, Wenyan, Cheung, Fiona Ka Man, Qiu, JianWen, Qian, PeiYuan. Adaptation to deep-sea chemosynthetic environments as revealed by mussel genomes. NATURE ECOLOGY & EVOLUTION[J]. 2017, 第 4 作者1(5): http://ir.idsse.ac.cn/handle/183446/5917.
[43] Li, Jun, Zhang, Yuehuan, Mao, Fan, Tong, Ying, Liu, Ying, Zhang, Yang, Yu, Ziniu. Characterization and Identification of Differentially Expressed Genes Involved in Thermal Adaptation of the Hong Kong Oyster Crassostrea hongkongensis by Digital Gene Expression Profiling. FRONTIERS IN MARINE SCIENCE[J]. 2017, 第 6 作者 通讯作者 4: https://doaj.org/article/4d0cdba757e84f6c8f7d478e81447949.
[44] JiaLin Wang, Tusar T Saha, Yang Zhang, Changyu Zhang, Alexander S Raikhel. Juvenile hormone and its receptor methoprene-tolerant promote ribosomal biogenesis and vitellogenesis in the Aedes aegypti mosquito. THE JOURNAL OF BIOLOGICAL CHEMISTRY. 2017, 第 3 作者292(24): 10306-10315, http://dx.doi.org/10.1074/jbc.M116.761387.
[45] Zhang, Yuehuan, Li, Jun, Zhang, Yang, Ma, Haitao, Xiao, Shu, Xiang, Zhiming, Yu, Ziniu. Performance evaluation of reciprocal hybrids derived from the two brackish oysters, Crassostrea hongkongensis and Crassostrea sikamea in southern China. AQUACULTURE[J]. 2017, 第 3 作者473: 310-316, http://dx.doi.org/10.1016/j.aquaculture.2017.02.031.
[46] 刘映, 李军, 张跃环, 张扬, 喻子牛. 香港牡蛎新型LRR受体克隆与功能分析. 水产学报[J]. 2017, 第 4 作者41(3): 347-357,
[47] 张跃环, 武祥伟, 秦艳平, 肖述, 马海涛, 李军, 张扬, 喻子牛. 美国熊本牡蛎基础群体构建及生产性能评估. 中国水产科学[J]. 2017, 第 7 作者24(5): 1020-1026, http://lib.cqvip.com/Qikan/Article/Detail?id=673155528.
[48] Qu, Fufa, Xiang, Zhiming, Xiao, Shu, Wang, Fuxuan, Li, Jun, Zhang, Yang, Zhang, Yuehuan, Qin, Yanping, Yu, Ziniu. c-Jun N-terminal kinase (JNK) is involved in immune defense against bacterial infection in Crassostrea hongkongensis. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY[J]. 2017, 第 6 作者67: 77-85, http://dx.doi.org/10.1016/j.dci.2016.11.011.
[49] Li, Jun, Zhang, Yang, Zhang, Yuehuan, Mao, Fan, Xiang, Zhiming, Xiao, Shu, Ma, Haitao, Yu, Ziniu. The first invertebrate NFIL3 transcription factor with role in immune defense identified from the Hong Kong oyster, Crassostrea hongkongensis. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY[J]. 2017, 第 2 作者76: 1-8, http://dx.doi.org/10.1016/j.dci.2017.05.011.
[50] 张跃环, 肖述, 李军, 马海涛, 张扬, 向志明, 喻子牛. 砗蚝(Hippopus hippopus)的人工繁育. 海洋与湖沼[J]. 2017, 第 5 作者48(5): 1030-1035, https://d.wanfangdata.com.cn/periodical/hyyhz201705015.
[51] Mao, Fan, Li, Jun, Zhang, Yuehuan, Xiang, Zhiming, Zhang, Yang, Yu, Ziniu. Molecular cloning and functional analysis of tumor necrosis factor receptor-associated factor 6 (TRAF6) in Crossastrea gigas. FISH & SHELLFISH IMMUNOLOGY[J]. 2017, 第 5 作者 通讯作者 68: 37-45, http://dx.doi.org/10.1016/j.fsi.2017.06.049.
[52] 张跃环, 肖述, 李军, 马海涛, 向志明, 张扬, 喻子牛. 鳞砗磲的人工繁育和早期发生. 水产学报[J]. 2016, 第 6 作者40(11): 1713-1723, https://d.wanfangdata.com.cn/periodical/scxb201611007.
[53] Jun Li, Ying Liu, Yuehuan Zhang, Yang Zhang, Fan Mao, Ziniu Yu. The first NFIL3/E4BP4 transcription factor with immune defense identified in the Hong Kong oyster, Crassostrea hongkongensis. FISH AND SHELLFISH IMMUNOLOGY. 2016, 第 4 作者53: 121-121, http://dx.doi.org/10.1016/j.fsi.2016.04.113.
[54] Zhang, Yang, Zhao, Bo, Roy, Sourav, Saha, Tusar T, Kokoza, Vladimir A, Li, Ming, Raikhel, Alexander S. microRNA-309 targets the Homeobox gene SIX4 and controls ovarian development in the mosquito Aedes aegypti. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2016, 第 1 作者113(33): E4828-E4836, http://ir.scsio.ac.cn/handle/344004/15305.
[55] Zhang, Yuehuan, Zhang, Yang, Jun, Li, Wang, Zhaoping, Yan, Xiwu, Yu, Ziniu. Phenotypic trait of Crassostrea hongkongensis female x C. angulata male hybrids in southern China. AQUACULTURE RESEARCH[J]. 2016, 第 2 作者47(11): 3399-3409, http://ir.scsio.ac.cn/handle/344004/15267.
[56] Li, Jun, Zhang, Yuehuan, Liu, Ying, Zhang, Yang, Xiao, Shu, Yu, Ziniu. Co-expression of heat shock protein (HSP) 40 and HSP70 in Pinctada martensii response to thermal, low salinity and bacterial challenges. FISH & SHELLFISH IMMUNOLOGY[J]. 2016, 第 4 作者48: 239-243, http://dx.doi.org/10.1016/j.fsi.2015.11.038.
[57] Qu, Fufa, Xiang, Zhiming, Zhang, Yang, Li, Jun, Xiao, Shu, Zhang, Yuehuan, Mao, Fan, Ma, Haitao, Yu, Ziniu. A novel p38 MAPK indentified from Crassostrea hongkongensis and its involvement in host response to immune challenges. MOLECULAR IMMUNOLOGY[J]. 2016, 第 3 作者79: 113-124, http://dx.doi.org/10.1016/j.molimm.2016.10.001.
[58] 张跃环, 秦艳平, 武祥伟, 周颖力, 肖述, 李军, 张扬, 马海涛, 向志明. 熊本牡蛎无嵴和多嵴品系生产性状比较. 水产学报[J]. 2016, 第 7 作者40(12): 1883-1888, https://d.wanfangdata.com.cn/periodical/scxb201612009.
[59] 张跃环, 秦艳平, 张扬, 李军, 肖述, 向志明, 马海涛, 喻子牛. 熊本牡蛎(Crassostrea sikamea)多嵴和无嵴品系子二代生长性状的选择效应. 海洋与湖沼[J]. 2016, 第 3 作者47(3): 581-586, https://d.wanfangdata.com.cn/periodical/hyyhz201603012.
[60] Li, Jun, Zhang, Yuehuan, Liu, Ying, Zhang, Yang, Xiang, Zhiming, Qu, Fufa, Yu, Ziniu. A thymosin beta-4 is involved in production of hemocytes and immune defense of Hong Kong oyster, Crassostrea hongkongensis. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY[J]. 2016, 第 4 作者 通讯作者 57: 1-9, http://dx.doi.org/10.1016/j.dci.2015.12.007.
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[69] Xu, Fengjiao, Li, Jun, Zhang, Yuehuan, Li, Xiaomei, Zhang, Yang, Xiang, Zhiming, Yu, Ziniu. CgI kappa B3, the third novel inhibitor of NF-kappa B (I kappa B) protein, is involved in the immune defense of the Pacific oyster, Crassostrea gigas. FISH & SHELLFISH IMMUNOLOGY[J]. 2015, 第 5 作者 通讯作者 46(2): 648-655,
[70] 向志明. Xu F, Zhang Y, Li J, Xiang ZM, Yu ZN*. Expression and Function analysis of two Naturally Truncated MyD88 variants in the Pacific oyster Crassostrea gigas. Fish Shellfish Immunol. 2015 45(2):510-6.. Fish Shellfish Immunol. 2015,
[71] Xu, Fengjiao, Zhang, Yang, Li, Jun, Zhang, Yuehuan, Xiang, Zhiming, Yu, Ziniu. Expression and function analysis of two naturally truncated MyD88 variants in the Pacific oyster Crassostrea gigas. FISH & SHELLFISH IMMUNOLOGY[J]. 2015, 第 2 作者 通讯作者 45(2): 510-516, http://dx.doi.org/10.1016/j.fsi.2015.04.034.
[72] Zhang, Yang, Sun, Jin, Mu, Huawei, Li, Jun, Zhang, Yuehuan, Xu, Fengjiao, Xiang, Zhiming, Qian, PeiYuan, Qiu, JianWen, Yu, Ziniu. Proteomic Basis of Stress Responses in the Gills of the Pacific Oyster Crassostrea gigas. JOURNAL OF PROTEOME RESEARCH[J]. 2015, 第 1 作者14(1): 304-317, http://dx.doi.org/10.1021/pr500940s.
[73] Mingjia Yu, Yuehuan Zhang, Xu Tang, Jun Ren, Yang Zhang. The first mollusk spätzle homolog gene in the clam, Paphia undulate. FISH AND SHELLFISH IMMUNOLOGY. 2015, 第 5 作者47(2): 712-716, http://dx.doi.org/10.1016/j.fsi.2015.10.017.
[74] Fengjiao Xu, Jun Li, Yuehuan Zhang, Xiaomei Li, Yang Zhang, Zhiming Xiang, Ziniu Yu. CgIκB3, the third novel inhibitor of NF-kappa B (IκB) protein, is involved in the immune defense of the Pacific oyster, Crassostrea gigas. FISH AND SHELLFISH IMMUNOLOGY. 2015, 第 5 作者46(2): 648-655, http://dx.doi.org/10.1016/j.fsi.2015.08.002.
[75] Jun Li, Yang Zhang, Yuehuan Zhang, Ying Liu, Zhiming Xiang, Fufa Qu, Ziniu Yu. Cloning and characterization of three suppressors of cytokine signaling (SOCS) genes from the Pacific oyster, Crassostrea gigas. FISH AND SHELLFISH IMMUNOLOGY. 2015, 第 2 作者44(2): 525-532, http://dx.doi.org/10.1016/j.fsi.2015.03.022.
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[81] Ying Tong, Yang Zhang, Jiaomei Huang, Shu Xiao, Yuehuan Zhang, Jun Li, Jinhui Chen, Ziniu Yu. Transcriptomics Analysis of Crassostrea hongkongensis for the Discovery of Reproduction-Related Genes.. PLOS ONE[J]. 2015, 第 2 作者 通讯作者 10(8): https://doaj.org/article/61f7d521fba74ce3bb3a48aeb8c9f2d6.
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[86] Wang, Jingjing, Zhang, Yang, Liu, Xianling, Ma, Jinan, Liu, Ping, Hu, Chunhong, Zhang, Guangsen. Annexin A5 inhibits diffuse large B-cell lymphoma cell invasion and chemoresistance through phosphatidylinositol 3-kinase signaling. ONCOLOGY REPORTS[J]. 2014, 第 2 作者32(6): 2557-2563, https://www.webofscience.com/wos/woscc/full-record/WOS:000344904900034.
[87] Jun Li, Yang Zhang, Yuehuan Zhang, Zhiming Xiang, Ying Tong, Fufa Qu, Ziniu Yu. Genomic characterization and expression analysis of five novel IL-17 genes in the Pacific oyster, Crassostrea gigas. FISH AND SHELLFISH IMMUNOLOGY. 2014, 第 2 作者40(2): 455-465, http://dx.doi.org/10.1016/j.fsi.2014.07.026.
[88] Zhang, Shen, Zhang, Yang, Chen, Wanping, Wu, Yangsheng, Ge, Wei, Zhang, Lihong, Zhang, Weimin. Aromatase (Cyp19a1b) in the Pituitary Is Dynamically Involved in the Upregulation of lhb But Not fshb in the Vitellogenic Female Ricefield Eel Monopterus albus. ENDOCRINOLOGY[J]. 2014, 第 2 作者155(11): 4531-4541, https://www.webofscience.com/wos/woscc/full-record/WOS:000343422800040.
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[91] Zhang, Yang, Li, Jun, Yu, Feng, Tong, Ying, Zhang, Yuehuan, Xiang, Zhiming, Yu, Ziniu. Identification and functional characterization of SIMPL in Crassostrea gigas reveals its ancient origin and involvement in the regulation of Rel/NF-kappa B transcription activity. FISH & SHELLFISH IMMUNOLOGY[J]. 2014, 第 1 作者40(1): 239-244, https://www.webofscience.com/wos/woscc/full-record/WOS:000341468500028.
[92] Xiang, Zhiming, Qu, Fufa, Qi, Lin, Zhang, Yang, Xiao, Shu, Yu, Ziniu. A novel ortholog of serum response factor (SRF) with immune defense function identified in Crassostrea hongkongensis. FISH & SHELLFISH IMMUNOLOGY[J]. 2014, 第 4 作者36(1): 75-82, http://dx.doi.org/10.1016/j.fsi.2013.10.006.
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[94] Zhiming Xiang, Fufa Qu, Lin Qi, Yang Zhang, Shu Xiao, Ziniu Yu. A novel ortholog of serum response factor (SRF) with immune defense function identified in Crassostrea hongkongensis. FISH AND SHELLFISH IMMUNOLOGY. 2014, 第 4 作者36(1): 75-82, http://dx.doi.org/10.1016/j.fsi.2013.10.006.
[95] Xiang, Zhiming, Qu, Fufa, Li, Jun, Qi, Lin, Yang, Zhang, Kong, Xiaoyu, Yu, Ziniu. Activator protein-1 (AP-1) and response to pathogen infection in the Hong Kong oyster (Crassostrea hongkongensis). FISH & SHELLFISH IMMUNOLOGY[J]. 2014, 第 5 作者36(1): 83-89, http://dx.doi.org/10.1016/j.fsi.2013.10.005.
[96] Yuehuan Zhang, Yang Zhang, Zhaoping Wang, Xiwu Yan, Ziniu Yu. Phenotypic trait analysis of diploid and triploid hybrids from female Crassostrea hongkongensis × male C. gigas. AQUACULTURE. 2014, 第 2 作者434: 307-314, http://dx.doi.org/10.1016/j.aquaculture.2014.08.039.
[97] Zhiming Xiang, Fufa Qu, Jun Li, Lin Qi, Zhang Yang, Xiaoyu Kong, Ziniu Yu. Activator protein-1 (AP-1) and response to pathogen infection in the Hong Kong oyster (Crassostrea hongkongensis). FISH AND SHELLFISH IMMUNOLOGY. 2014, 第 5 作者36(1): 83-89, http://dx.doi.org/10.1016/j.fsi.2013.10.005.
[98] Huang, Jiaomei, Zhang, Yang, Li, Jun, Yu, Ziniu. Development of SNP markers in Crassostrea hongkongensis based on the next-generation sequencing and high resolution melting analysis. CONSERVATION GENETICS RESOURCES[J]. 2014, 第 2 作者6(3): 559-562, https://www.webofscience.com/wos/woscc/full-record/WOS:000340404900016.
[99] Zhang, Yuehuan, Zhang, Yang, Wang, Zhaoping, Yan, Xiwu, Yu, Ziniu. Phenotypic trait analysis of diploid and triploid hybrids from female Crassostrea hongkongensis x male C. gigas. AQUACULTURE[J]. 2014, 第 2 作者434: 307-314, https://www.webofscience.com/wos/woscc/full-record/WOS:000345058700044.
[100] Li, Jun, Zhang, Yang, Zhang, Yuehuan, Xiang, Zhiming, Tong, Ying, Qu, Fufa, Yu, Ziniu. Genomic characterization and expression analysis of five novel IL-17 genes in the Pacific oyster, Crassostrea gigas. FISH & SHELLFISH IMMUNOLOGY[J]. 2014, 第 2 作者40(2): 455-465, http://dx.doi.org/10.1016/j.fsi.2014.07.026.
[101] Zhang, Yang, Zhang, Shen, Lu, Huijie, Zhang, Lihong, Zhang, Weimin. Genes encoding aromatases in teleosts: Evolution and expression regulation. GENERAL AND COMPARATIVE ENDOCRINOLOGY[J]. 2014, 第 1 作者205: 151-158, http://dx.doi.org/10.1016/j.ygcen.2014.05.008.
[102] Yang Zhang, Jun Li, Feng Yu, Ying Tong, Yuehuan Zhang, Zhiming Xiang, Ziniu Yu. Identification and functional characterization of SIMPL in Crassostrea gigas reveals its ancient origin and involvement in the regulation of Rel/NF-κB transcription activity. FISH AND SHELLFISH IMMUNOLOGY. 2014, 第 1 作者239-244, http://dx.doi.org/10.1016/j.fsi.2014.07.014.
[103] Deng, Mingyang, Zhang, Guangsen, Zhang, Yang, Xiao, Han, Dai, Chongwen, Xu, Yunxiao, Zheng, Wenli, Peng, Hongling, Shen, Jiankai. Analysis of clinical and laboratory characteristics in 42 patients with thrombotic thrombocytopenic purpura from a single center in China. TRANSFUSION AND APHERESIS SCIENCE[J]. 2013, 第 3 作者49(3): 447-452, http://dx.doi.org/10.1016/j.transci.2013.07.026.
[104] Zhang, Yang, Zhang, Shen, Liu, Zhixin, Zhang, Lihong, Zhang, Weimin. Epigenetic Modifications During Sex Change Repress Gonadotropin Stimulation of Cyp19a1a in a Teleost Ricefield Eel (Monopterus albus). ENDOCRINOLOGY[J]. 2013, 第 1 作者154(8): 2881-2890, https://www.webofscience.com/wos/woscc/full-record/WOS:000322063900032.
[105] Xiang, Zhiming, Qu, Fufa, Qi, Lin, Zhang, Yang, Tong, Ying, Yu, Ziniu. Cloning, characterization and expression analysis of a caspase-8 like gene from the Hong Kong oyster, Crassostrea hongkongensis. FISH & SHELLFISH IMMUNOLOGY[J]. 2013, 第 4 作者35(6): 1797-1803, http://dx.doi.org/10.1016/j.fsi.2013.08.026.
[106] Yang Zhang, Ziniu Yu. The first evidence of positive selection in peptidoglycan recognition protein (PGRP) genes of Crassostrea gigas. FISHANDSHELLFISHIMMUNOLOGY. 2013, 第 1 作者1352-1355, http://dx.doi.org/10.1016/j.fsi.2013.01.018.
[107] Deng, Ting, Xu, Nong, Xiong, JianPing, Yan, Zhao, Zhuang, ZhiXiang, Yu, Zhuang, Wan, HuiPing, Zhang, Yang, Huang, DingZhi, Zheng, RongSheng, Guo, ZengQing, Hu, ChunHong, Wang, MeiLing, Yu, ZhongHe, Yao, Yang, Meng, JiChang, Ba, Yi. Safety analysis of weekly paclitaxel plus S-1 versus paclitaxel plus 5-fluorouracil/calcium folinate as first-line therapy in advanced gastric cancer: a multicenter open random phase II trial. JOURNAL OF CHEMOTHERAPY[J]. 2013, 第 8 作者25(1): 56-59, https://www.webofscience.com/wos/woscc/full-record/WOS:000314773400008.
[108] Li, Jun, Zhang, Yang, Xiang, Zhiming, Xiao, Shu, Yu, Feng, Yu, Ziniu. High mobility group box 1 can enhance NF-kappa B activation and act as a pro-inflammatory molecule in the Pacific oyster, Crassostrea gigas. FISH & SHELLFISH IMMUNOLOGY[J]. 2013, 第 2 作者35(1): 63-70, http://dx.doi.org/10.1016/j.fsi.2013.04.001.
[109] Yang Zhang, Jun Li, Feng Yu, Xiaocui He, Ziniu Yu. Allograft inflammatory factor-1 stimulates hemocyte immune activation by enhancing phagocytosis and expression of inflammatory cytokines in Crassostrea gigas. FISH AND SHELLFISH IMMUNOLOGY. 2013, 第 1 作者1071-1077, http://dx.doi.org/10.1016/j.fsi.2013.01.014.
[110] Zhang, Yang, Li, Jun, Yu, Feng, He, Xiaocui, Yu, Ziniu. Allograft inflammatory factor-1 stimulates hemocyte immune activation by enhancing phagocytosis and expression of inflammatory cytokines in Crassostrea gigas. FISH & SHELLFISH IMMUNOLOGY[J]. 2013, 第 1 作者34(5): 1071-1077, http://dx.doi.org/10.1016/j.fsi.2013.01.014.
[111] Zhang, Yang, He, Xiaocui, Yu, Feng, Xiang, Zhiming, Li, Jun, Thorpe, Karen L, Yu, Ziniu. Characteristic and Functional Analysis of Toll-like Receptors (TLRs) in the lophotrocozoan, Crassostrea gigas, Reveals Ancient Origin of TLR-Mediated Innate Immunity. PLOS ONE[J]. 2013, 第 1 作者8(10): https://doaj.org/article/0244fd54c1e44eb2b90db0d1d4c5715a.
[112] Jun Li, Yang Zhang, Zhiming Xiang, Shu Xiao, Feng Yu, Ziniu Yu. High mobility group box 1 can enhance NF-κB activation and act as a pro-inflammatory molecule in the Pacific oyster, Crassostrea gigas. FISH AND SHELLFISH IMMUNOLOGY. 2013, 第 2 作者35(1): 63-70, http://dx.doi.org/10.1016/j.fsi.2013.04.001.
[113] Huang, Dingzhi, Ba, Yi, Xiong, Jianping, Xu, Nong, Yan, Zhao, Zhuang, Zhixiang, Yu, Zhuang, Wan, Huiping, Zhang, Yang, Deng, Ting, Zheng, Rongsheng, Guo, Zengqing, Hu, Chunhong, Wang, Meiling, Yu, Zhonghe, Yao, Yang, Meng, Jichang. A multicentre randomised trial comparing weekly paclitaxel + S-1 with weekly paclitaxel+5-fluorouracil for patients with advanced gastric cancer. EUROPEAN JOURNAL OF CANCER[J]. 2013, 第 9 作者49(14): 2995-3002, http://dx.doi.org/10.1016/j.ejca.2013.05.021.
[114] Zhiming Xiang, Fufa Qu, Lin Qi, Yang Zhang, Ying Tong, Ziniu Yu. Cloning, characterization and expression analysis of a caspase-8 like gene from the Hong Kong oyster, Crassostrea hongkongensis. FISH AND SHELLFISH IMMUNOLOGY. 2013, 第 4 作者35(6): 1797-1803, http://dx.doi.org/10.1016/j.fsi.2013.08.026.
[115] Zhang, Yang, Yu, Ziniu. The first evidence of positive selection in peptidoglycan recognition protein (PGRP) genes of Crassostrea gigas. FISH & SHELLFISH IMMUNOLOGY[J]. 2013, 第 1 作者34(5): 1352-1355, http://dx.doi.org/10.1016/j.fsi.2013.01.018.
[116] Wu, Shikai, Zhang, Yang, Xu, Liyan, Dai, Yun, Teng, Yuee, Ma, Shanshan, Ho, SeongHyun, Kim, JongMook, Yu, Seung Shin, Kim, Sunyoung, Song, Santai. Multicenter, randomized study of genetically modified recombinant human interleukin-11 to prevent chemotherapy-induced thrombocytopenia in cancer patients receiving chemotherapy. SUPPORTIVE CARE IN CANCER[J]. 2012, 第 2 作者20(8): 1875-1884, https://www.webofscience.com/wos/woscc/full-record/WOS:000306129600034.
[117] Yang Zhang. Androgen rather than estrogen upregulates brain type cytochrome P450 aromatase gene via tissue specific promoters in the hermaphrodite teleost ricefiele eel, Monopterus albus.. Mol Cell Endocrinol.. 2012, 第 1 作者
[118] Li, YingHua, Gao, HaiFeng, Wang, Yan, Liu, Fang, Tian, XiaoFeng, Zhang, Yang. Overexpression of Gli1 in cancer interstitial tissues predicts early relapse after radical operation of breast cancer. CHINESE JOURNAL OF CANCER RESEARCH[J]. 2012, 第 6 作者 通讯作者 24(4): 263-274, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=4697947&detailType=1.
[119] Yang Zhang, Xiaocui He, Ziniu Yu. Two homologues of inhibitor of NF-kappa B (IκB) are involved in the immune defense of the Pacific oyster, Crassostrea gigas. FISH AND SHELLFISH IMMUNOLOGY. 2011, 第 1 作者30(6): 1354-1361, http://dx.doi.org/10.1016/j.fsi.2011.03.008.
[120] Yang Zhang, Xiaocui He, Xiaomei Li, Dingkun Fu, Jinhui Chen, Ziniu Yu. The second bactericidal permeability increasing protein (BPI) and its revelation of the gene duplication in the Pacific oyster, Crassostrea gigas. FISH AND SHELLFISH IMMUNOLOGY. 2011, 第 1 作者954-963, http://dx.doi.org/10.1016/j.fsi.2011.01.031.
[121] Xiaocui He, Yang Zhang, Ziniu Yu. An Mpeg (macrophage expressed gene) from the Pacific oyster Crassostrea gigas : Molecular characterization and gene expression. FISH AND SHELLFISH IMMUNOLOGY. 2011, 第 2 作者870-876, http://dx.doi.org/10.1016/j.fsi.2011.01.009.
[122] Yang Zhang, Dingkun Fu, Feng Yu, Qiongyou Liu, Ziniu Yu. Two catalase homologs are involved in host protection against bacterial infection and oxidative stress in Crassostrea hongkongensis. FISH AND SHELLFISH IMMUNOLOGY. 2011, 第 1 作者894-903, http://dx.doi.org/10.1016/j.fsi.2011.08.005.
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科研活动
1. 国家自然科学基金青年项目:太平洋牡蛎新型固有免疫模式识别受体NLR的克隆、功能和信号途径的研究 (31001130),2011-2013;
2. 国家高技术研究发展计划(863计划):牡蛎全基因组测序与功能解析(2010AA10A110),2010-2011;
3. 国家高技术研究发展计划(863计划):基于全基因组信息的贝类遗传选育(2012AA10A405) 2012-2015;
4. 南海所青年人才领域前沿项目:基于转录组的贝类抗病和免疫相关基因挖掘及功能研究(SQ200905),2010-2012;
5. 珠江科技新星:近江牡蛎新型抗病毒信号通路的鉴定和功能研究(2013J2200095)2013-2015。
2. 国家高技术研究发展计划(863计划):牡蛎全基因组测序与功能解析(2010AA10A110),2010-2011;
3. 国家高技术研究发展计划(863计划):基于全基因组信息的贝类遗传选育(2012AA10A405) 2012-2015;
4. 南海所青年人才领域前沿项目:基于转录组的贝类抗病和免疫相关基因挖掘及功能研究(SQ200905),2010-2012;
5. 珠江科技新星:近江牡蛎新型抗病毒信号通路的鉴定和功能研究(2013J2200095)2013-2015。
参与会议
(1) The proteomic study of plasma-opsonized activation of hemocyte phagocytosis in the pacific oyster, Crassostrea gigas,2013亚太水产养殖大会(APA13),2013-12,张扬