基本信息
杨玉荣  男  博导  中国科学院昆明植物研究所
办公电话: 0871-65223126
电子邮件: yangyurong@mail.kib.ac.cn
通信地址: 昆明市蓝黑路132号中国科学院昆明植物研究所

邮政编码: 650201

招生信息

   
招生专业
100701-药物化学
招生方向
天然产物全合成

教育背景

2005-11--2007-12   Harvard University    博士后
2000-09--2005-08   兰州大学   博士
1996-09--2000-08   兰州大学   学士

工作经历

   
工作简历
2008-01~现在, 昆明植物研究所, 研究员

教授课程

有机化学

专利与奖励

   
奖励信息
(1) 中国科学院优秀导师奖, 院级, 2019
(2) 领雁银奖(振翅奖), 院级, 2019
(3) 中国科学院优秀导师奖, , 院级, 2018
专利成果
[1] 杨玉荣, 梁箫, 李磊, 韦堃. 秋水仙碱和别秋水仙碱的不对称合成方法. CN: CN110963937A, 2020-04-07.

出版信息

   
发表论文
[1] 杨玉荣. Catalytic, Asymmetric Total Synthesis of (+)-α , (+)-β , (+)-γ , and (−)-δ-Lycorane. Organic Letters[J]. 2022, 24: 2905-2909, [2] Liang, Xiao, Li, Lei, Wei, Kun, Yang, YuRong. Gram-Scale, Seven-Step Total Synthesis of (-)-Colchicine. ORGANIC LETTERS[J]. 2021, 23(7): 2731-2735, [3] Deng, Yi, Liang, Xiao, Wei, Kun, Yang, YuRong. Ir-Catalyzed Asymmetric Total Syntheses of Bisdehydrotuberostemonine D, Putative Bisdehydrotuberostemonine E and Structural Revision of the Latter. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2021, 143(49): 20622-20627, [4] Zhang, TianYuan, Deng, Yi, Wei, Kun, Yang, YuRong. Enantioselective Iridium-Catalyzed Allylic Alkylation of Racemic Branched Alkyl-Substituted Allylic Acetates with Malonates. ORGANIC LETTERS[J]. 2021, 23(3): 1086-1089, http://dx.doi.org/10.1021/acs.orglett.0c04309.
[5] Li, Lei, Shi, Li, Wei, Kun, Yang, YuRong. Asymmetric Total Synthesis of (+)-Quinocarcinamide. ORGANIC LETTERS[J]. 2021, 23(20): 7972-7975, [6] Zheng, Yu, Yang, HongDou, Wei, Kun, Yang, YuRong. Synthetic Studies toward Parvistemoline Using Asymmetric Ir/Amine-Catalyzed Allylation. JOURNAL OF ORGANIC CHEMISTRY[J]. 2021, 86(8): 6025-6029, http://dx.doi.org/10.1021/acs.joc.1c00390.
[7] Zheng, Yu, Li, XueDan, Sheng, PengZhen, Yang, HongDou, Wei, Kun, Yang, YuRong. Asymmetric Total Syntheses of (-)-Fennebricin A, (-)-Renieramycin J, (-)-Renieramycin G, (-)-Renieramycin M, and (-)- Jorunnamycin A via C-H Activation. ORGANIC LETTERS[J]. 2020, 22(11): 4489-4493, http://ir.kib.ac.cn/handle/151853/72118, http://www.irgrid.ac.cn/handle/1471x/6927931, http://ir.kib.ac.cn/handle/151853/72119, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000538848600084&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=3a85505900f77cc629623c3f2907beab.
[8] Meng, ChunYan, Liang, Xiao, Wei, Kun, Yang, YuRong. Enantioselective Ir-Catalyzed Allylic Alkylation of Racemic Allylic Alcohols with Malonates. ORGANIC LETTERS[J]. 2019, 21(3): 840-843, http://ir.kib.ac.cn/handle/151853/64241.
[9] Yao, JianNeng, Liang, Xiao, Wei, Kun, Yang, YuRong. Catalytic, Enantioselective Formal Synthesis of Monoterpene Indole Alkaloid (-)-Alstoscholarine. ORGANIC LETTERS[J]. 2019, 21(20): 8485-8487, [10] Meng, ChunYan, Liang, Xiao, Zhang, Hongbin, Wei, Kun, Yang, YuRong. Stereocontrolled concise synthesis of (+/-)-halosaline through intramolecular C-H amination. TETRAHEDRON LETTERS[J]. 2019, 60(27): 1781-1783, [11] Yue, BeiBei, Deng, Yi, Zheng, Yu, Wei, Kun, Yang, YuRong. Iridium-Catalyzed Enantioselective Allylation of Aryl Enamides and Enecarbamates. ORGANIC LETTERS[J]. 2019, 21(7): 2449-2452, https://www.webofscience.com/wos/woscc/full-record/WOS:000464247500110.
[12] Yue, BeiBei, Deng, Yi, Zheng, Yu, Wei, Kun, Yang, YuRong. Iridium-Catalyzed Enantioselective Allylation of Aryl Enamides and Enecarbamates. ORGANIC LETTERS[J]. 2019, 21(7): 2449-2452, https://www.webofscience.com/wos/woscc/full-record/WOS:000464247500110.
[13] Yu, Yang, Bao, MeiFen, Wu, Jing, Yang, YuRong, Chen, Jing, Schinnerl, Johann, Cai, XiangHai. Tabernabovines A-C: Three Monoterpenoid Indole Alkaloids from the Leaves of Tabernaemontana bovina. ORGANIC LETTERS[J]. 2019, 21(15): 5938-5942, [14] Zheng, Yu, Yue, BeiBei, Wei, Kun, Yang, YuRong. Short Synthesis of the Monoterpene Indole Alkaloid (+/-)-Arbornamine. JOURNAL OF ORGANIC CHEMISTRY[J]. 2018, 83(8): 4867-4870, https://www.webofscience.com/wos/woscc/full-record/WOS:000430898500056.
[15] Zheng, Yu, Yue, BeiBei, Wei, Kun, Yang, YuRong. Iridium-Catalyzed Enantioselective Allyl-Allyl Cross-Coupling of Racemic Allylic Alcohols with Allylboronates. ORGANIC LETTERS[J]. 2018, 20(24): 8035-8038, http://ir.kib.ac.cn/handle/151853/64370.
[16] Liang, Xiao, Zhang, TianYuan, Meng, ChunYan, Li, XueDan, Wei, Kun, Yang, YuRong. Total Synthesis of (-)-Actinophyllic Acid Enabled by a Key Dual Ir/Amine-Catalyzed Allylation. ORGANIC LETTERS[J]. 2018, 20(15): 4575-4578, https://www.webofscience.com/wos/woscc/full-record/WOS:000441112700042.
[17] Liang, Xiao, Zhang, TianYuan, Zeng, XueYi, Zheng, Yu, Wei, Kun, Yang, YuRong. Ir-Catalyzed Asymmetric Total Synthesis of (-)-Communesin F. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2017, 139(9): 3364-3367, http://ir.kib.ac.cn/handle/151853/50996.
[18] Zheng, Yu, Wei, Kun, Yang, YuRong. Total Synthesis of (-)-Geissoschizol through Ir-Catalyzed Allylic Amidation as the Key Step. ORGANIC LETTERS[J]. 2017, 19(23): 6460-6462, https://www.webofscience.com/wos/woscc/full-record/WOS:000417229000050.
[19] Jiang, ShiZhi, Zeng, XueYi, Liang, Xiao, Lei, Ting, Wei, Kun, Yang, YuRong. Iridium-Catalyzed Enantioselective Indole Cyclization: Application to the Total Synthesis and Absolute Stereochemical Assignment of (-)-AspidophyllineA. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2016, 55(12): 4044-4048, http://ir.kib.ac.cn/handle/151853/26181.
[20] Liang, Xiao, Jiang, ShiZhi, Wei, Kun, Yang, YuRong. Enantioselective Total Synthesis of (-)-Alstoscholarisine A. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2016, 138(8): 2560-2562, http://ir.kib.ac.cn/handle/151853/26005.
[21] Liang, Xiao, Wei, Kun, Yang, YuRong. Iridium-catalyzed enantioselective allylation of silyl enol ethers derived from ketones and alpha,beta-unsaturated ketone. CHEMICAL COMMUNICATIONS[J]. 2015, 51(98): 17471-17474, http://www.irgrid.ac.cn/handle/1471x/1029002.
[22] Lei, Ting, Zhang, Hongbin, Yang, YuRong. Iridium-catalyzed enantioselective synthesis of (-)- and (+)-aurantioclavine. TETRAHEDRON LETTERS[J]. 2015, 56(43): 5933-5936, http://dx.doi.org/10.1016/j.tetlet.2015.09.039.
[23] Dong, LiaoBin, Wu, YaNan, Jiang, ShiZhi, Wu, XingDe, He, Juan, Yang, YuRong, Zhao, QinShi. Isolation and Complete Structural Assignment of Lycopodium Alkaloid Cernupalhine A: Theoretical Prediction and Total Synthesis Validation. ORGANIC LETTERS[J]. 2014, 16(10): 2700-2703, http://www.irgrid.ac.cn/handle/1471x/845924.
[24] Jiang, ShiZhi, Lei, Ting, Wei, Kun, Yang, YuRong. Collective Total Synthesis of Tetracyclic Diquinane Lycopodium Alkaloids (+)-Paniculatine, (-)-Magellanine, (+)-Magellaninone and Analogues Thereof. ORGANIC LETTERS[J]. 2014, 16(21): 5612-5615, http://www.irgrid.ac.cn/handle/1471x/929643.
[25] Xu, Tao, Luo, XiuLi, Yang, YuRong. Asymmetric total synthesis of Lycopodium alkaloid (+)-lycopladine A. TETRAHEDRON LETTERS[J]. 2013, 54(22): 2858-2860, http://dx.doi.org/10.1016/j.tetlet.2013.03.097.
[26] 杨玉荣. Synthetic Studies on the Paniculatine-type Lycopodium Alkaloids. 天然产物全合成—青年学术研讨会论文摘要[J]. 2012, 2-, http://www.irgrid.ac.cn/handle/1471x/637544.
[27] Yang, YuRong, Shen, Liang, Huang, JiuZhong, Xu, Tao, Wei, Kun. Application of the Helquist Annulation in Lycopodium Alkaloid Synthesis: Unified Total Syntheses of (-)-8-Deoxyserratinine, (-)-Fawcettimine, and (+)-Lycoflexine. JOURNAL OF ORGANIC CHEMISTRY[J]. 2011, 76(10): 3684-3690, http://www.irgrid.ac.cn/handle/1471x/392924.
[28] Yang, YuRong, Lai, ZengWei, Shen, Liang, Huang, JiuZhong, Wu, XingDe, Yin, JunLin, Wei, Kun. Total Synthesis of (-)-8-Deoxyserratinine via an Efficient Helquist Annulation and Double N-Alkylation Reaction. ORGANIC LETTERS[J]. 2010, 12(15): 3430-3433, https://www.webofscience.com/wos/woscc/full-record/WOS:000280398900038.
[29] Li, WDZ, Yang, YR. Unusual cyclopropanation of 9-bromocamphor derivatives: A novel formal C(1)-C(7) bond cleavage of camphor. ORGANIC LETTERS[J]. 2005, 7(14): 3107-3110, https://www.webofscience.com/wos/woscc/full-record/WOS:000230213100077.
[30] Yang, YR, Li, WDZ. A short synthesis of 10-hydroxy 7-spirocyclopropanated camphor. JOURNAL OF ORGANIC CHEMISTRY[J]. 2005, 70(20): 8224-8227, https://www.webofscience.com/wos/woscc/full-record/WOS:000232166800057.

科研活动

   
科研项目
( 1 ) 三环二萜Vinigrol不对称全合成研究, 主持, 国家级, 2009-01--2011-12
( 2 ) 石松生物碱Lycopaniculatine全合成研究, 主持, 国家级, 2011-01--2013-12
( 3 ) ****择优支持, 主持, 部委级, 2011-05--2014-05
( 4 ) 若干灯台碱不对称催化全合成研究, 主持, 国家级, 2015-01--2018-12
( 5 ) 天然产物与类天然产物的合成, 参与, 国家级, 2009-01--2013-12
( 6 ) 若干重要吲哚生物碱不对称全合成研究, 主持, 国家级, 2017-01--2020-12
( 7 ) 吲哚生物碱不对称合成 新策略研究, 主持, 部委级, 2016-01--2020-12
( 8 ) 重要单萜吲哚生物碱全合成研究, 主持, 省级, 2017-06--2020-05
( 9 ) 抗生素Teicoplanin Aglycon全合成研究, 主持, 国家级, 2020-01--2023-12
参与会议
(1)Ir-Catalyzed Asymmetric Total Synthesis of Two Alkaloids   第9届中韩有机化学研讨会   2019-11-30
(2)Ir-catalyzed total syntheses of indole alkaloids   第十三届亚洲有机化学前沿国际会议   2018-11-01
(3)Ir-Catalyzed Asymmetric Total Synthesis of ()-Actinophyllic Acid   2018 年中国化学会年会   2018-05-07
(4)Asymmetric Cyclization Strategies for the Total Syntheses of Three Indole Alkaloids   第10届全国有机化学会   2017-12-18
(5)Ir-catalyzed total syntheses of indole alkaloids   首届美国化学学会(ACS)亚太地区国际分会会议   2017-11-06
(6)Asymmetric indole cyclization strategy for the total synthesis of monoterpenoid indole alkaloids   第六届中泰双边天然产物与药物发现研讨会   2016-10-17
(7)Asymmetric indole cyclization strategies for the total syntheses of monoterpene indole alkaloids   第三届天然产物合成和药物先进制造方法国际研讨会   2016-10-15
(8)Asymmetric indole cyclization strategies for the total syntheses of monoterpene indole alkaloids   第十一届天然有机化学会议   2016-09-26
(9)Asymmetric indole cyclization strategies for the total syntheses of monoterpene indole alkaloids   第五届天然产物全合成青年学术研讨会   2016-07-21
(10)Total Synthesis and Assignment of Absolute Stereochemistry of Akuammiline Alkaloid (-)-Aspidophylline A   第8届中韩双边有机化学研讨会   杨玉荣   2016-02-01
(11)若干石松生物碱全合成研究   中国化学会第九届全国有机化学学术会议   杨玉荣   2015-08-20
(12)石松生物碱 (+)-Paniculatine, ()-Magellanine and (+)-Magellaninone的全合成研究   第四届中国化学会天然产物全合成青年学者论坛   杨玉荣   2015-07-10

指导学生

已指导学生

沈亮  硕士研究生  077901-药物化学  

徐弢  硕士研究生  077901-药物化学  

罗秀丽  硕士研究生  077901-药物化学  

吴雅男  硕士研究生  077901-药物化学  

雷婷  博士研究生  100701-药物化学  

江世智  博士研究生  100701-药物化学  

曾雪怡  硕士研究生  078001-药物化学  

董廖斌  博士研究生  100701-药物化学  

章天元  硕士研究生  078001-药物化学  

梁箫  博士研究生  100701-药物化学  

岳蓓蓓  硕士研究生  078001-药物化学  

李雪丹  硕士研究生  078001-药物化学  

郑瑜  博士研究生  100701-药物化学  

石鑫  博士研究生  100701-药物化学  

现指导学生

章天元  博士研究生  100701-药物化学  

姚建能  博士研究生  100701-药物化学  

盛彭真  博士研究生  100701-药物化学  

李磊  博士研究生  100701-药物化学  

李朋华  博士研究生  100701-药物化学  

张泸月  硕士研究生  078001-药物化学  

张园园  博士研究生  100701-药物化学  

丁倩辉  硕士研究生  078001-药物化学  

邓屹  博士研究生  100701-药物化学  

首坤秀  博士研究生  100701-药物化学