0402Z2-认知神经科学
071006-神经生物学

灵长类运动控制及运动学习的脑机制研究
多感觉信息的整合对运动计时的影响
神经环路在运动计时中的作用

2002-09--2007-07   中国科学院生物物理研究所   理学博士
1998-09--2002-07   云南大学理学院物理系   理学学士

   

2012-06~2015-12,美国杜克大学医学院, Research Associate
2007-11~2012-05,美国加州大学旧金山分校, 博士后

2018-01-01-2022-12-31,Science Bulletin, 副主编

神经生物学
系统神经科学
科研实践I-科研训练（2021夏）
高级神经科学
分子神经生物学
本科生毕业设计（生物科学）
科研实践II
高级分子及系统神经生物学

   

（1） The Best Conference Presentation at Gordon Research Conference on Cerebellum, 特等奖, 其他, 2011
（2） Fellowship at the Gordon Research Conference, Eye Movements, 其他, 2011
（3） 张香桐神经科学研究生论文一等奖, 一等奖, 国家级, 2009

   

[1] 陈怡冰, 王欢, 杨艳. Optical-neural Stimulation in Non-human Primates: Modulating Brain Function and Behavior. 生物化学与生物物理进展[J]. 2024, 第 3 作者  通讯作者  null(null): 
[2] Lasse Knudsen, Bo Jespersen, Mia B. Heintzelmann, Peng Zhang, 杨艳, Torben E. Lund, Jakob U. Blicher,. Laminar fMRI in the locked-in stage of amyotrophic lateral sclerosis shows preserved activity in layer Vb of primary motor cortex. Aperture Neuro[J]. 2024, 第 5 作者null(null): 
[3] Suhao Chen, Shuli Zhang, Yang Li, Huan Wang, Xun Chen, Yan Yang. Dual-channel neural network for instance segmentation of synapse. Computers in Biology and Medicine[J]. 2024, 第 6 作者  通讯作者  172(null): 
[4] Hu, Yongxiang, Wang, Huan, Joshua, Mati, Yang, Yan. Sensorimotor-linked reward modulates smooth pursuit eye movements in monkeys. FRONTIERS IN NEUROSCIENCE[J]. 2024, 第 4 作者  通讯作者  17: http://dx.doi.org/10.3389/fnins.2023.1297914.
[5] 曹丹丹, 刘祖祥, 赖昭宇, 吕钊, 舒伟, 王欢, 杨艳. 老化对视觉注意调控网络的影响. 生物化学与生物物理进展[J]. 2023, 第 7 作者50(11): 2721-2728, http://www.pibb.ac.cn/pibbcn/article/abstract/20220539?st=article_issue.
[6] Xiao, Tong, Wu, Kaijie, Wang, Peiliang, Ding, Yali, Yang, Xiao, Chang, Chao, Yang, Yan. Sensory input-dependent gain modulation of the optokinetic nystagmus by mid-infrared stimulation in pigeons. ELIFE[J]. 2023, 第 7 作者  通讯作者  12: http://dx.doi.org/10.7554/eLife.78729.
[7] Huan Wang, Xiaoxiao Wang, Yanming Wang, Du Zhang, Yan Yang, Yifeng Zhou, Bensheng Qiu, Peng Zhang. White matter BOLD signals at 7 Tesla reveal visual field maps in optic radiation and vertical occipital fasciculus. NEUROIMAGE[J]. 2023, 第 5 作者269: 119916, http://dx.doi.org/10.1016/j.neuroimage.2023.119916.
[8] Wang, Xiaolu, Liu, Zhiqiang, Angelov, Milen, Feng, Zhao, Li, Xiangning, Li, Anan, Yang, Yan, Gong, Hui, Gao, Zhenyu. Excitatory nucleo-olivary pathway shapes cerebellar outputs for motor control. NATURE NEUROSCIENCE. 2023, 第 7 作者26(8): 1394-1406, http://dx.doi.org/10.1038/s41593-023-01387-4.
[9] Lasse Knudsen, Christopher J Bailey, Jakob U Blicher, Yan Yang, Peng Zhang, Torben E Lund. Improved sensitivity and microvascular weighting of 3T laminar fMRI with GE-BOLD using NORDIC and phase regression. NEUROIMAGE. 2023, 第 4 作者271: http://dx.doi.org/10.1016/j.neuroimage.2023.120011.
[10] Dou, Huixi, Wang, Huan, Liu, Sainan, Huang, Jun, Liu, Zuxiang, Zhou, Tiangang, Yang, Yan. Form Properties of Moving Targets Bias Smooth Pursuit Target Selection in Monkeys. NEUROSCIENCE BULLETIN[J]. 2023, 第 7 作者  通讯作者  39(8): 1246-1262, http://dx.doi.org/10.1007/s12264-023-01022-z.
[11] Wang, Xiaohui, Cui, Xiaoli, Li, Yang, Li, Fei, Dai, Jinye, Li, Yue, Hu, Han, Wang, Xuefeng, Sun, Jianyuan, Yang, Yan, Zhang, Shuli. MC4R Deficiency Causes Dysregulation of Postsynaptic Excitatory Synaptic Transmission as a Crucial Culprit for Obesity. DIABETES[J]. 2022, 第 10 作者  通讯作者  71: 2331-2343, https://diabetesjournals.org/diabetes/article-abstract/71/11/2331/147382/MC4R-Deficiency-Causes-Dysregulation-of?redirectedFrom=fulltext.
[12] Cui, Xiaoli, Zhang, Ruijin, Yang, Ye, Wu, Erzhong, Tang, Yiheng, Zhao, Zhihua, Li, Chao, Yang, Lei, Teng, Xueyi, Ye, Yanzhen, Cui, Ya, Xu, Feng, Su, Zewen, Wang, Dongpeng, Zhang, Dongdong, Yang, Yan, Sun, Jianyuan, Luo, Jianjun, Zhang, Shuli, Chen, Runsheng, Xi, Jianzhong Jeff. Identification and characterization of long non-coding RNA Carip in modulating spatial learning and memory. CELL REPORTS[J]. 2022, 第 16 作者38(8): 
[13] Hall, Nathan J, Yang, Yan, Lisberger, Stephen G. Multiple components in direction learning in smooth pursuit eye movements of monkeys. JOURNAL OF NEUROPHYSIOLOGY[J]. 2018, 第 2 作者120(4): 2020-2035, https://www.webofscience.com/wos/woscc/full-record/WOS:000451350100049.
[14] Yang, Yan, Lisberger, Stephen G. Modulation of Complex-Spike Duration and Probability during Cerebellar Motor Learning in Visually Guided Smooth-Pursuit Eye Movements of Monkeys. ENEURO[J]. 2017, 第 1 作者  通讯作者  4(3): http://dx.doi.org/10.1523/ENEURO.0115-17.2017.
[15] Yang, Yan, Wang, Qian, Wang, ShuRong, Wang, Yi, Xiao, Qian. Representation of time interval entrained by periodic stimuli in the visual thalamus of pigeons. ELIFE[J]. 2017, 第 1 作者6: https://doaj.org/article/ba613b6498e846d7af0b51b2db414874.
[16] Huang, Jun, Yang, Yan, Zhou, Ke, Zhao, Xudong, Zhou, Quan, Zhu, Hong, Yang, Yingshan, Zhang, Chunming, Zhou, Yifeng, Zhou, Wu. Rapid Processing of a Global Feature in the ON Visual Pathways of Behaving Monkeys. FRONTIERS IN NEUROSCIENCE[J]. 2017, 第 2 作者11: https://doaj.org/article/5e57d9388ba64dad96f69db429ef1538.
[17] Yang Yan, Lisberger Stephen G.. Role of Plasticity at Different Sites across the Time Course of Cerebellar Motor Learning. THE JOURNAL OF NEUROSCIENCE[J]. 2014, 第 1 作者  通讯作者  34(21): 7077-7090, https://www.webofscience.com/wos/woscc/full-record/WOS:000336895200006.
[18] Yang, Yan, Lisberger, Stephen G. Purkinje-cell plasticity and cerebellar motor learning are graded by complex-spike duration. NATURE[J]. 2014, 第 1 作者  通讯作者  510(7506): 529-+, https://www.webofscience.com/wos/woscc/full-record/WOS:000337806300045.
[19] Yang, Yan, Lisberger, Stephen G. Interaction of plasticity and circuit organization during the acquisition of cerebellum-dependent motor learning. ELIFE[J]. 2013, 第 1 作者2: https://doaj.org/article/4621da89575b4560acc30b634f6c3df1.
[20] Yang, Yan, Lisberger, Stephen G. Learning on Multiple Timescales in Smooth Pursuit Eye Movements. JOURNAL OF NEUROPHYSIOLOGY[J]. 2010, 第 1 作者104(5): 2850-2862, https://www.webofscience.com/wos/woscc/full-record/WOS:000285392000047.
[21] 杨艳, 曹鹏, 杨杨, 王书荣. 家鸽视觉系统扫视抑制的伴随放电神经回路. 中国基础科学[J]. 2009, 第 1 作者11(1): 19-20, http://lib.cqvip.com/Qikan/Article/Detail?id=29635924.
[22] Yang, Yang, Yang, Yan, Wang, ShuRong. Neuronal Circuitry and Discharge Patterns Controlling Eye Movements in the Pigeon. JOURNAL OF NEUROSCIENCE[J]. 2008, 第 2 作者28(42): 10772-10780, http://www.irgrid.ac.cn/handle/1471x/757606.
[23] Yang, Yan, Cao, Peng, Yang, Yang, Wang, ShuRong. Corollary discharge circuits for saccadic modulation of the pigeon visual system. NATURE NEUROSCIENCE[J]. 2008, 第 1 作者11(5): 595-602, http://www.irgrid.ac.cn/handle/1471x/757647.
[24] Cao, P, Yang, Y, Yang, Y, Wang, SR. Differential modulation of thalamic neurons by optokinetic nuclei in the pigeon. BRAIN RESEARCH[J]. 2006, 1069(1): 159-165, http://dx.doi.org/10.1016/j.brainres.2005.11.063.
[25] Zheng, JW, Yang, Y, Tian, SH, Chen, J, Wilson, FAW, Ma, YY. The dynamics of hippocampal sensory gating during the development of morphine dependence and withdrawal in rats. NEUROSCIENCE LETTERS[J]. 2005, 382(1-2): 164-168, http://dx.doi.org/10.1016/j.neulet.2005.03.010.

   

（ 1 ） 系统神经生物学, 负责人, 国家任务, 2018-01--2020-12
（ 2 ） 灵长类运动学习和控制神经机制的研究, 负责人, 中国科学院计划, 2016-01--2020-12
（ 3 ） 基本情绪和视觉基本单元的相互作用及“ 大范围首先”的皮层下通路神经表达, 参与, 国家任务, 2018-01--2022-12
（ 4 ） 奖赏调控运动学习的神经机制研究, 负责人, 国家任务, 2021-01--2024-12
（ 5 ） 面向运动功能的穿戴式脑磁图原理研究及应用探索, 负责人, 地方任务, 2021-08--2025-08

（1）Reward modulated cerebellar motor learning in monkeys   2022北京脑科学国际学术大会   2022-08-14
（2）Form properties of moving targets bias smooth pursuit target selection in monkeys   自动化大会   2022-08-13
（3）Cerebellar climbing fibers convey reward signals during motor learning in monkeys   美国神经科学大会   Huyue Liu, Yongxiang Hu   2019-10-19

已指导学生

汪旭  硕士研究生  0771Z2-认知神经科学  

窦汇溪  硕士研究生  0771Z2-认知神经科学  

现指导学生

刘虎跃  博士研究生  0402Z2-认知神经科学  

徐茜  博士研究生  071006-神经生物学  

李清文  博士研究生  071006-神经生物学  

杨荣芳  硕士研究生  086000-生物与医药  

廖加凤  博士研究生  071006-神经生物学  

肖彤  博士研究生  0402Z2-认知神经科学  

黄捷频  博士研究生  0402Z2-认知神经科学  

赖昭宇  硕士研究生  086000-生物与医药  

田雨  硕士研究生  0771Z2-认知神经科学