不对称合成，有机小分子催化，金属催化，动力学拆分

招收福州大学以及福建师范大学联培硕士生

070303-有机化学

不对称合成，小分子催化，动力学拆分

2009-09--2014-06   南开大学   博士
2005-09--2009-06   南开大学   学士

博士

博士

2017-01~现在, 中国科学院福建物质结构研究所, 副研究员
2014-07~2017-01,中国科学院福建物质结构研究所, 助理研究员

2017-01~现在, 中国科学院福建物质结构研究所, 副研究员
2014-07~2017-01,中国科学院福建物质结构研究所, 助理研究员

   

[1] 陈丽, 杨爽, 房新强, 黄煌江. Catalytic synthesis of seven-membered carbocycles via ring expansion of cyclic b-ketoesters. New Journal of Chemistry[J]. 2023, 
[2] Shuang Yang, Xinqiang Fang. Asymmetric hydrogenation and transfer hydrogenation of diketones. TETRAHEDRON[J]. 2023, 145: http://dx.doi.org/10.1016/j.tet.2023.133609.
[3] 杨爽, 房新强. 氮杂环卡宾催化 实现 的动力学拆分 -近期研究进展. Chinese Journal of Organic Chemistry[J]. 2023, 
[4] 陈丽, 杨爽, 房新强. Organocatalyzed trifunctionalization of alkynyl 1,2-diones for the concise synthesis of acyloxy allylidene malonates and γ-alkylidenebutenolides. Green Chemistry[J]. 2022, 
[5] 兰首昂, 刘锐, 杨爽, 房新强. Ti(OiPr)4-Facilitated Formal Deoxygenative Annulation of Alkynyl 1,2-Diketones for the Synthesis of Highly Functionalized Furans. Organic Letters[J]. 2021, 
[6] Chen, Zhizhou, Kong, Xiangwen, Niu, Shengtong, Yang, Shuang, Liu, Jinggong, Chen, Bolai, Luo, Benlong, Zhou, Changyu, Ding, Chenglin, Fang, Xinqiang. N-Heterocyclic Carbene-Catalyzed Asymmetric Synthesis of Cyclopentenones. ORGANIC LETTERS[J]. 2021, 23(9): 3403-3408, http://dx.doi.org/10.1021/acs.orglett.1c00870.
[7] Liu, Jian, Vasamsetty, Laxmaiah, Anwar, Muhammad, Yang, Shuang, Xu, Weici, Liu, Jinggong, Nagaraju, Sakkani, Fang, Xinqiang. Organocatalyzed Kinetic Resolution of alpha-Functionalized Ketones: The Malonate Unit Leads the Way. ACS CATALYSIS[J]. 2020, 10(5): 2882-2893, https://www.webofscience.com/wos/woscc/full-record/WOS:000518876300001.
[8] 孙德谦, 杨爽, 房新强. Asymmetric Catalytic Construction of Fully-Substituted Carbon Stereocenters Using Acyclic α-Branched β-Ketocarbonyls: The "Methyl Rule" Widely Exists. Organic Chemistry Frontiers[J]. 2020, 
[9] Li, Xinglong, Kong, Xiangwen, Yang, Shuang, Meng, Miao, Zhan, Xinyue, Zeng, Min, Fang, Xinqiang. Bifunctional Thiourea-Catalyzed Asymmetric Inverse-Electron-Demand Diels-Alder Reaction of Allyl Ketones and Vinyl 1,2-Diketones via Dienolate Intermediate. ORGANIC LETTERS[J]. 2019, 21(7): 1979-1983, https://www.webofscience.com/wos/woscc/full-record/WOS:000464247500009.
[10] Yang, Shuang, Fang, Xinqiang. Kinetic Resolutions Enabled by N-Heterocyclic Carbene Catalysis. CURRENT ORGANIC SYNTHESIS. 2017, 14(5): 654-664, https://www.webofscience.com/wos/woscc/full-record/WOS:000408271800002.
[11] Yang, Shuang, Che, Wen, Wu, HuiLing, Zhu, ShouFei, Zhou, QiLin. Neutral iridium catalysts with chiral phosphine-carboxy ligands for asymmetric hydrogenation of unsaturated carboxylic acids. CHEMICAL SCIENCE[J]. 2017, 8(3): 1977-1980, http://dx.doi.org/10.1039/c6sc03764j.
[12] Li, MaoLin, Yang, Shuang, Su, XunCheng, Wu, HuiLing, Yang, LiangLiang, Zhu, ShouFei, Zhou, QiLin. Mechanism Studies of Ir-Catalyzed Asymmetric Hydrogenation of Unsaturated Carboxylic Acids. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2017, 139(1): 541-547, https://www.webofscience.com/wos/woscc/full-record/WOS:000392036900072.
[13] Lin, Qiqiao, Li, Yuanzhen, Das, Deb Kumar, Zhang, Guoxiang, Zhao, Zhifei, Yang, Shuang, Fang, Xinqiang. N-Heterocyclic carbene-catalyzed desymmetrization of functionalized 1,4-dienes via Stetter Reaction. CHEMICAL COMMUNICATIONS[J]. 2016, 52(38): 6459-6462, https://www.webofscience.com/wos/woscc/full-record/WOS:000375624100026.
[14] 杨爽. Carboxy-directed asymmetric hydrogenation of a-alkyl-a-aryl terminal olefins: Highly enantioselective and chemoselective access to chiral benzylmethyl center. Organic & Biomolecular Chemistry. 2014, 
[15] 杨爽. Enantioselective iridium-catalyzed hydrogenation of a-arylcinnamic acids and synthesis of (S)-equol. Tetrahedron. 2012, 

   

（ 1 ） 氮杂环卡宾催化的不对称去对称化反应构筑季碳手性中心, 主持, 国家级, 2016-01--2018-12
（ 2 ） 基于新型手性2-氨基-1-羟基茚的催化剂和配体的设计合成及应用, 主持, 省级, 2018-04--2021-04
（ 3 ） 动态动力学拆分反应合成 三立体中心苯并二氢吡喃类天然产物, 主持, 研究所（学校）, 2019-01--2020-12