基本信息

徐梦佳 女 中国科学院宁波材料技术与工程研究所
电子邮件: xumengjia@nimte.ac.cn
通信地址: 浙江省宁波市慈溪市学林路99号
邮政编码: 315300
电子邮件: xumengjia@nimte.ac.cn
通信地址: 浙江省宁波市慈溪市学林路99号
邮政编码: 315300
教育背景
2017-09--2020-09 中国科学院大学 博士2014-09--2015-11 伦敦国王学院 硕士2010-09--2014-06 南京农业大学 学士
工作经历
工作简历
2020-12~2023-04,南京农业大学, 博士后2016-05~2017-08,中国科学院宁波材料技术与工程研究所, 科研助理
专利与奖励
专利成果
( 1 ) 一种比率型银纳米簇荧光探针及其制备方法与应用, 发明专利, 2022, 第 1 作者, 专利号: CN114456802A( 2 ) 一种microRNAs检测试剂盒及检测方法和应用, 发明专利, 2020, 第 3 作者, 专利号: CN111718985A( 3 ) 一种巯基功能化肽核酸增强银纳米簇荧光信号检测单核酸多态性的方法及其应用, 发明专利, 2019, 第 5 作者, 专利号: CN110331190A( 4 ) 基因缺失突变的荧光检测试剂盒和荧光检测方法, 发明专利, 2021, 第 5 作者, 专利号: CN108949924B( 5 ) 一种单核苷酸多态性的比色检测方法及试剂盒, 发明专利, 2018, 第 4 作者, 专利号: CN108753925A( 6 ) 一种凝血酶检测方法及其试剂盒, 发明专利, 2018, 第 1 作者, 专利号: CN108760657A( 7 ) 一种凝血酶检测方法及其试剂盒, 2021, 第 1 作者, 专利号: CN108760657B( 8 ) 一种检测单核苷酸多态性的方法, 发明专利, 2019, 第 1 作者, 专利号: CN110205359A
出版信息
发表论文
[1] Xiaowen Hua, Mengjia Xu, Ming Yang, Yingying Zhang, Jianke Ma, Li Cheng, Chu Chu, Zimiao Wu, Mingquan Guo. Hypoglycemic and hypolipidemic bioactive compounds from edible traditional Chinese medicines and their action of mechanisms explored by multitarget affinity ultrafiltration with liquid chromatography–mass spectrometry. FOOD FRONTIERS[J]. 2025, 第 2 作者6(1): 65-85, http://dx.doi.org/10.1002/fft2.488.[2] Xiaomeng Yu, Shuyu Ding, Yang Zhao, Mengjia Xu, Zimiao Wu, Chao Zhao. A highly sensitive and robust electrochemical biosensor for microRNA detection based on PNA-DNA hetero-three-way junction formation and target-recycling catalytic hairpin assembly amplification. TALANTA[J]. 2024, 第 4 作者266(null): http://dx.doi.org/10.1016/j.talanta.2023.125020.[3] Chen, ChongHao, Xu, MengJia, Zheng, Qi, Li, DongDong, Cheng, Li, Sun, Juan, Wu, ZiMiao. Biological evaluation of carbazoyl hydrazine derivatives as potential Pim-1 kinase inhibitors for the treatment of human liver cancer. JOURNAL OF MOLECULAR STRUCTURE[J]. 2024, 第 2 作者1295: http://dx.doi.org/10.1016/j.molstruc.2023.136742.[4] Fuqiang Song, Anqi Ye, Linyuan Jiang, Yang Lu, Yanzhen Feng, Rong Huang, Siting Du, Xiaoyu Dong, Ting Huang, Ping Li, Liangliang Yang, Jinjing Zhang, Mengjia Xu, Li Cheng, Jian Xiao. Photothermal-enhanced silver nanocluster bioactive glass hydrogels for synergistic antimicrobial and promote wound healing. MATERIALS TODAY BIO. 2024, 第 13 作者30: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11785576/.[5] Wei, Hua, Yu, Shengkai, Zhang, Yansheng, Zhang, Hua, Ma, Yuxi, Xu, Mengjia, An, Peng, Zhou, Yang, Halila, Sami, Wei, Yen, Chen, Jing. Injectable chitosan/xyloglucan composite hydrogel with mechanical adaptivity and endogenous bioactivity for skin repair. CARBOHYDRATE POLYMERS[J]. 2023, 第 6 作者313: http://dx.doi.org/10.1016/j.carbpol.2023.120904.[6] Wang, Xiaomeng, Tian, Juanjuan, Tang, Nanyu, Zhang, Xueliang, Xiao, Luyao, Xu, Mengjia, Dong, Mingsheng, Li, Wei. In vitro simulated digestion and fecal fermentation of exopolysaccharides from Lacticaseibacillus paracasei GL1. FOOD & FUNCTION[J]. 2023, 第 6 作者14(11): 5120-5137, http://dx.doi.org/10.1039/d3fo00676j.[7] Cao, Juan, Xu, Zihao, Xu, Mengjia, Ma, Yuhui, Zhao, Yitian. A two-stage framework for optical coherence tomography angiography image quality improvement. FRONTIERS IN MEDICINE[J]. 2023, 第 3 作者 通讯作者 10: http://dx.doi.org/10.3389/fmed.2023.1061357.[8] 徐梦佳, 冯慧霞, 郭明全. Potential hypoglycemic and hypolipidemic bioactive constituents in Cyclocarya paliurus leaves explored by affinity ultrafiltration with α‐glucosidase and pancreatic lipase. eFood[J]. 2023, 第 1 作者null(null): [9] Xu, Mengjia, Li, Zhi, Zhao, Xiaogan, Li, Wei. Prebiotic Properties of Exopolysaccharides from Lactobacillus helveticus LZ-R-5 and L. pentosus LZ-R-17 Evaluated by In Vitro Simulated Digestion and Fermentation. FOODS[J]. 2022, 第 1 作者11(16): [10] Xiaomeng Wang, Mengjia Xu, Danling Xu, Kai Ma, Changliang Zhang, Guangxian Wang, Mingsheng Dong, Wei Li. Structural and prebiotic activity analysis of the polysaccharide produced by Lactobacillus helveticus SNA12. CARBOHYDRATE POLYMERS. 2022, 第 2 作者296: http://dx.doi.org/10.1016/j.carbpol.2022.119971.[11] Guo, ShuaiJun, Chang, HaoYun, Xu, MengJia, Wang, ChenXu, Wei, Hua, Li, DongDong, Chen, Jing, Zhou, Yang, Liu, Yi. Co2+-Mediated Hydrogels with Enhanced Mechanical Properties for Flexible Sensing. ACS APPLIED POLYMER MATERIALS[J]. 2022, 第 3 作者4(9): 6403-6413, http://dx.doi.org/10.1021/acsapm.2c00812.[12] Mengjia Xu, Xiaomeng Wang, Juanjuan Tian, Jing Chen, Xiaojie Wei, Wei Li. A clamp-improved universal amplified system for ratiometric fluorescent detection of single-nucleotide polymorphisms coupled with a novel dual-emissive silver nanocluster. Sensors and Actuators B: Chemical[J]. 2022, 第 1 作者367: 132151, [13] Fu, Pan, Xu, Mengjia, Xing, Shu, Zhao, Yang, Zhao, Chao. Dual cascade isothermal amplification reaction based glucometer sensors for point-of-care diagnostics of cancer-related microRNAs. ANALYST[J]. 2021, 第 2 作者146(10): 3242-3250, http://dx.doi.org/10.1039/d1an00037c.[14] Mengjia Xu, Shu Xing, Yang Zhao, Chao Zhao. Peptide nucleic acid-assisted colorimetric detection of single-nucleotide polymorphisms based on the intrinsic peroxidase-like activity of hemin-carbon nanotube nanocomposites. TALANTA. 2021, 第 1 作者232: http://dx.doi.org/10.1016/j.talanta.2021.122420.[15] Xiaomeng Wang, Wenpei Li, Mengjia Xu, Juanjuan Tian, Wei Li. The Microbial Diversity and Biofilm-Forming Characteristic of Two Traditional Tibetan Kefir Grains. FOODS[J]. 2021, 第 3 作者11(1): https://doaj.org/article/a5c57ff0e49340929f037e75f90ea007.[16] 徐梦佳. 基于功能肽核酸探针的生物传感器构建及其在疾病标志物快速检测中的应用研究. 中国科学院大学(中国科学院宁波材料技术与工程研究所). 2020, 第 1 作者https://t.cnki.net/kcms/detail?v=3uoqIhG8C447WN1SO36whFuPQ0yKi4pXSQlJ_W8wBD9JRPlAs_d8B6yLEBs9cAjtjImLCilViE7Wij5r0U_g5YMryzRrxiPm.[17] Fu, Pan, Xing, Shu, Xu, Mengjia, Zhao, Yang, Zhao, Chao. Peptide nucleic acid-based electrochemical biosensor for simultaneous detection of multiple microRNAs from cancer cells with catalytic hairpin assembly amplification. SENSORS AND ACTUATORS B-CHEMICAL[J]. 2020, 第 3 作者305: http://dx.doi.org/10.1016/j.snb.2019.127545.[18] Xu, Mengjia, Fu, Pan, Xing, Shu, Zhao, Yang, Zhao, Chao. A PNA-DNA(2) Triple-Helix Molecular Switch-Based Colorimetric Sensor for Sensitive and Specific Detection of microRNAs from Cancer Cells. CHEMBIOCHEM[J]. 2020, 第 1 作者21(18): 2667-2675, http://dx.doi.org/10.1002/cbic.202000155.[19] Gao, Tingting, Xing, Shu, Xu, Mengjia, Fu, Pan, Yao, Jiechen, Zhang, Xiaokang, Zhao, Yang, Zhao, Chao. A peptide nucleic acid-regulated fluorescence resonance energy transfer DNA assay based on the use of carbon dots and gold nanoparticles. MICROCHIMICA ACTA[J]. 2020, 第 3 作者187(7): https://www.webofscience.com/wos/woscc/full-record/WOS:000541857300001.[20] Xing, Shu, Xu, Xiaojun, Fu, Pan, Xu, Mengjia, Gao, Tingting, Zhang, Xiaokang, Zhao, Chao. Colorimetric detection of single base-pair mismatches based on the interactions of PNA and PNA/DNA complexes with unmodified gold nanoparticles. COLLOIDS AND SURFACES B-BIOINTERFACES[J]. 2019, 第 4 作者181: 333-340, http://dx.doi.org/10.1016/j.colsurfb.2019.05.069.[21] Xu, Xiaojun, Xing, Shu, Xu, Mengjia, Fu, Pan, Gao, Tingting, Zhang, Xiaokang, Zhao, Yang, Zhao, Chao. Highly sensitive and specific screening of EGFR mutation using a PNA microarray-based fluorometric assay based on rolling circle amplification and graphene oxide. RSC ADVANCES[J]. 2019, 第 3 作者9(66): 38298-38308, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000509401700001.[22] Xu, Wanxing, Xing, Shu, Xu, Xiaojun, Xu, Mengjia, Fu, Pan, Gao, Tingting, Zhao, Chao. Peptide Nucleic Acid-Assisted Label-free Detection of Single-Nucleotide Polymorphisms Based on Light Scattering of Carbon Nanotubes. ACS OMEGA[J]. 2018, 第 4 作者3(12): 17835-17841, https://www.webofscience.com/wos/woscc/full-record/WOS:000454244600158.[23] Xu, Mengjia, Xing, Shu, Xu, Xiaojun, Fu, Pan, Xu, Wanxing, Zhao, Chao. Label-free colorimetric aptasensor for highly sensitive and selective detection of proteins by using PNA/DNA hybrids and a cyanine dye. ANALYTICAL METHODS[J]. 2018, 第 1 作者10(31): 3824-3829, http://ir.nimte.ac.cn/handle/174433/17254.[24] Yip, Yan Y, Pernigo, Stefano, Sanger, Anneri, Xu, Mengjia, Parsons, Maddy, Steiner, Roberto A, Dodding, Mark P. The light chains of kinesin-1 are autoinhibited. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2016, 第 4 作者113(9): 2418-2423, https://www.webofscience.com/wos/woscc/full-record/WOS:000371204500046.