基本信息
徐富强  男  博导  中国科学院深圳先进技术研究院
电子邮件: fq.xu@siat.ac.cn
通信地址: 广东省深圳市南山区西丽深圳大学城学苑大道1068号
邮政编码: 518055

招生信息

   
招生专业
071006-神经生物学
070302-分析化学
招生方向
神经生物学
微生物学
分析化学

教育背景

1998-08--2001-06   Yale Medical School   博士后
1998-06--1998-07   U of Kentucky   博士后
1994-09--1998-05   U of Kentucky   Ph. D, Physiology
1991-09--1994-05   U of Kentucky    Ph. D, Chemistry
1983-09--1986-07   兰州大学   硕士
1979-09--1983-07   兰州大学   学士
学历
-- 研究生
学位
-- 博士

工作经历

   
工作简历
2019-06~现在, 中国科学院深圳先进技术研究院, 研究员
2007-03~2022-04,中科院武汉物理与数学研所, 研究员
2001-07~2007-03,Yale MRRC, 副研究员
1988-08~1990-07,Indiana University, 学习
1986-08~1988-07,兰州大学, 讲师

专利与奖励

   
专利成果
[1] 吴阳, 徐富强、, 王杰, 韩增鹏, 王起恬, 金鼎瑜, 骆能松. 一种rAAV载体核心质粒及其应用. 202111297198.0, 2021-11-04.

[2] 苏鹏, 王华东, 徐富强. 一种神经环路标记系统. CN: CN112501137A, 2021-03-16.

[3] 王杰, 郑丹昊, 蔡奥灵, 刘惠丽, 李爽, 徐富强. 一种适用于磁共振成像仪的小动物生物安全微循环装置. CN: CN112426145A, 2021-03-02.

[4] 贾凡, 徐富强. 一种新型G基因及其在高效逆向跨单突触中的应用. CN: CN112210565A, 2021-01-12.

[5] 贾凡, 徐富强. 一种重组腺相关病毒及其制备方法和在抗体检测的应用. CN: CN112143712A, 2020-12-29.

[6] 林坤章, 徐富强. 减毒型水泡性口炎病毒突变体的全长感染性克隆及其应用. CN: CN111979252A, 2020-11-24.

[7] 林坤章, 徐富强. 具有变异衣壳蛋白的腺相关病毒及其应用. CN: CN111825772A, 2020-10-27.

[8] 林坤章, 徐富强, 文鹏杰, 何晓斌. 一种GABA能神经元特异性启动子及其应用. CN: CN111808862A, 2020-10-23.

[9] WU, Yang, XU, Fuqiang, MEI, Ting, JIANG, Liangyu, HAN, Zengpeng. METHOD, SYSTEM AND RECOMBINANT BACMID FOR PREPARATION OF RECOMBINANT ADENO-ASSOCIATED VIRUS. CN: US20200208175(A1), 2020-07-02.

[10] 郑宁, 张志建, 何晓斌, 苏鹏, 林坤章, 蔡奥灵, 卢晨, 王杰, 徐富强. 一种基于磁共振成像的活体示踪大脑神经连接的方法及其应用. CN: CN110452925A, 2019-11-15.

[11] 林坤章, 徐富强, 钟鑫, 何晓斌. CRE和FLP双重组酶级联控制的逆行跨单突触的辅助载体及其应用. CN: CN110331166A, 2019-10-15.

[12] 王华东, 徐富强, 苏鹏, 夏金金, 胡亮, 李颖利, 钟鑫. 低毒单纯疱疹病毒系统及其构建方法和应用. CN: CN110117577A, 2019-08-13.

[13] 王华东, 徐富强, 夏金金, 苏鹏, 李颖利, 林坤章. 一种携带荧光Timer基因可变色的重组单纯疱疹病毒及制备方法和应用. CN: CN110029127A, 2019-07-19.

[14] 靳森, 孙佩, 徐富强, 张玉慧, 陶斯珏. 用于辅助重组狂犬病毒在神经细胞高效逆向跨单级突触的rAAV病毒的包装方法及其应用. CN: CN110004118A, 2019-07-12.

[15] 贾凡, 徐富强, 李莉, 缪欢, 吕培, 施祥玮. 一种高亮表达红色荧光蛋白的逆向神经环路示踪的重组伪狂犬病毒的制备方法和应用. CN: CN109943539A, 2019-06-28.

[16] 靳森, 孙佩, 徐富强, 张玉慧, 陶斯珏. 神经细胞稀疏高亮度标记重组腺相关病毒的包装方法及其应用. CN: CN109880807A, 2019-06-14.

[17] 蔡奥灵, 王杰, 徐富强. 一种简易的小动物核磁共振成像仪适用的机械痛刺激装置. CN: CN109602419A, 2019-04-12.

[18] 吴阳, 徐富强, 梅婷, 蒋良玉, 韩增鹏. 重组腺相关病毒的制备方法、系统及重组杆粒. CN: CN109609552A, 2019-04-12.

[19] 苏鹏, 郑宁, 林坤章, 徐富强. 携带绿色荧光蛋白以及转铁蛋白的水疱性口炎病毒感染性克隆及制备方法和应用. CN: CN108277208A, 2018-07-13.

[20] WU, Yang, XU, Fuqiang, HE, Xiaobin, LIN, Kunzhang. METHOD FOR PREPARING RECOMBINANT ADENO-ASSOCIATED VIRUS. US: US20180163228(A1), 2018-06-14.

[21] WU, Yang, XU, Fuqiang, HE, Xiaobin. RECOMBINANT BACULOVIRUS AND METHOD OF USING THE SAME FOR PREPARING RECOMBINANT ADENO-ASSOCIATED VIRUS VECTOR. US: US20180155740(A1), 2018-06-07.

[22] WU, Yang, XU, Fuqiang, HE, Xiaobin. METHOD OF PREPARING RECOMBINANT ADENO-ASSOCIATED VIRUS AND RECOMBINANT BACULOVIRUS. US: US20180155697(A1), 2018-06-07.

[23] 吴阳, 徐富强, 何晓斌, 蔡泽蕲, 蒋良玉, 梅婷, 尚敏. 一种昆虫细胞的光控表达载体及应用. CN: CN107937437A, 2018-04-20.

[24] 贾凡, 徐富强, 徐小琴, 缪欢, 吕培. 一种Cre和Flp依赖的逆向示踪重组伪狂犬病毒的制备方法和应用. CN: CN107699589A, 2018-02-16.

[25] 王华东, 徐富强, 何晓斌, 靳森, 郑宁. 一种减毒增亮、复制可控的HSV重组病毒及制备方法和应用. CN: CN107630009A, 2018-01-26.

[26] 贾凡, 徐富强, 徐小琴, 缪欢. 一种高灵敏表达绿色荧光蛋白的逆向神经环路示踪的重组伪狂犬病毒的制备方法和应用. CN: CN106995824A, 2017-08-01.

[27] 吴阳, 徐富强, 何晓斌, 林坤章. 一种重组腺相关病毒的制备方法. CN: CN106987603A, 2017-07-28.

[28] 吴阳, 徐富强, 何晓斌. 一种重组腺相关病毒的制备方法及重组杆状病毒. CN: CN106916793A, 2017-07-04.

[29] 贾凡, 徐富强, 胡新天, 吴诗昊, 朱续涛. 一种用于非人灵长类神经细胞快速标记的西门利克森林病毒复制子及应用. CN: CN106754756A, 2017-05-31.

[30] 贾凡, 徐富强, 朱续涛, 靳森, 曾绍群, 刚亚栋. 一种西门利克森林病毒复制子及其在稀疏或精细神经元标记中的应用. CN: CN106754755A, 2017-05-31.

[31] 吴阳, 徐富强, 何晓斌. 一种重组杆状病毒及其应用. CN: CN106544325A, 2017-03-29.

[32] 贾凡, 徐富强. 复制耐受型的西门利克森林病毒的亚克隆及制备方法和应用. CN: CN105176936A, 2015-12-23.

[33] 贾凡, 徐富强, 朱续涛. 稳定携带绿色荧光蛋白基因的乙型脑炎病毒全长感染性克隆及制备方法和应用. CN: CN104946669A, 2015-09-30.

[34] 王杰, 程吉, 徐富强. 一种核磁共振波谱谱峰对齐及谱峰提取方法. CN: CN104458785A, 2015-03-25.

[35] 贾凡, 朱续涛, 徐富强. 携带绿色荧光蛋白基因的乙型脑炎病毒全长感染性克隆及制备方法和应用. CN: CN104357459A, 2015-02-18.

[36] 王杰, 刘泽源, 徐富强. 一种简易新型实验用麻醉机. CN: CN104248476A, 2014-12-31.

出版信息

   
发表论文
(1) Influence of Cerebral Glucose Metabolism by Chronic Pain-Mediated Cognitive Impairment in Adolescent Rats, MOLECULAR NEUROBIOLOGY, 2022, 第 8 作者
(2) A visual circuit related to the periaqueductal gray area for the antinociceptive effects of bright light treatment, Neuron, 2022, 其他(合作组作者)
(3) Restoration of FMRP expression in adult V1 neurons rescues visual deficits in a mouse model of fragile X syndrome, PROTEIN & CELL, 2022, 第 18 作者
(4) Brain-wide TVA compensation allows rabies virus to retrograde target cell-type-specific projection neurons, Molecular Brain, 2022, 通讯作者
(5) Anatomical Evidence for the Neural Connection from the Emotional Brain to Autonomic Innervation in the Anterior Chamber Structures of the Eye, CURRENT MEDICAL SCIENCE, 2022, 通讯作者
(6) A new anterograde trans-synaptic tracer based on Sindbis virus, Neural Regeneration Research, 2022, 通讯作者
(7) In vivo imaging of astrocytes in the whole brain with engineered AAVs and diffusion-weighted magnetic resonance imaging, Molecular Psychiatry, 2022, 通讯作者
(8) Mapping brain-wide excitatory projectome of primate prefrontal cortex at submicron resolution and comparison with diffusion tractography, eLife, 2022, 第 18 作者
(9) Construction of a mouse model of Posner-Schlossman syndrome by anterior chamber infection with cytomegalovirus, Experimental Eye Research, 2022, 第11作者
(10) Dopamine modulates visual threat processing in the superior colliculus via D2 receptors, iScience, 2022, 第 13 作者
(11) Social touch-like tactile stimulation activates a tachykinin 1-oxytocin pathway to promote social interactions, NEURON, 2022, 第 9 作者
(12) Long-term follow-up of dynamic brain changes in patients recovered from COVID-19 without neurological manifestations, JCI Insight, 2022, 第 13 作者
(13) Hierarchy in sensory processing reflected by innervation balance on cortical interneurons, SCIENCE ADVANCES, 2021, 第 14 作者
(14) Identification of metabolic kinetic patterns in different brain regions using metabolomics methods coupled with various discriminant approaches, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 第 8 作者
(15) A Visual Circuit Related to the Nucleus Reuniens for the Spatial-Memory-Promoting Effects of Light Treatment, NEURON, 2021, 第 13 作者
(16) Anatomical evidence for the efferent pathway from the hypothalamus to autonomic innervation in the anterior chamber structures of eyes, EXPERIMENTAL EYE RESEARCH, 2021, 通讯作者
(17) Mutation in epsilon-Sarcoglycan Induces a Myoclonus-Dystonia Syndrome-Like Movement Disorder in Mice, NEUROSCIENCE BULLETIN, 2021, 第11作者
(18) Long-term microstructure and cerebral blood flow changes in patients recovered from COVID-19 without neurological manifestations, JOURNAL OF CLINICAL INVESTIGATION, 2021, 其他(合作组作者)
(19) Popularizing Recombinant Baculovirus-derived OneBac System for Laboratory Production of all Recombinant Adeno-associated Virus Vector Serotypes, CURRENT GENE THERAPY, 2021, 通讯作者
(20) Frontal-posterior functional imbalance and aberrant function developmental patterns in schizophrenia, TRANSLATIONAL PSYCHIATRY, 2021, 通讯作者
(21) Abnormal neocortex arealization and Sotos-like syndrome-associated behavior in Setd2 mutant mice, SCIENCE ADVANCES, 2021, 第 10 作者
(22) Chemical sectioning fluorescence tomography: high-throughput, high-contrast, multicolor, whole-brain imaging at subcellular resolution, CELL REPORTS, 2021, 第 18 作者
(23) High-throughput mapping of a whole rhesus monkey brain at micrometer resolution, NATURE BIOTECHNOLOGY, 2021, 第 17 作者
(24) Developing of focal ischemia in the hippocampus or the amygdala reveals a regional compensation rule for fear memory acquisition, eNeuro, 2021, 第 1 作者
(25) A mathematical method for calibrating the signal drift in liquid chromatography - mass spectrometry analysis, TALANTA, 2021, 第11作者
(26) A new GABAergic somatostatin projection from the BNST onto accumbal parvalbumin neurons controls anxiety, MOLECULAR PSYCHIATRY, 2021, 第 8 作者
(27) Development of a rabies virus-based retrograde tracer with high trans-monosynaptic efficiency by reshuffling glycoprotein, MOLECULAR BRAIN, 2021, 第 8 作者
(28) Neuropeptide S Attenuates the Alarm Pheromone-Evoked Defensive and Risk Assessment Behaviors Through Activation of Cognate Receptor-Expressing Neurons in the Posterior Medial Amygdala, Frontiers in Molecular Neuroscience, 2021, 第 10 作者
(29) Whole-Brain Mapping the Direct Inputs of Dorsal and Ventral CA1 Projection Neurons, FRONTIERS IN NEURAL CIRCUITS, 2021, 通讯作者
(30) Investigation of metabolic kinetics in different brain regions of awake rats using the 1H-13C-NMR technique, Journal of Pharmaceutical and Biomedical Analysis, 2021, 第11作者
(31) Variations of Brain Functional Connectivity in Alcohol-Preferring and Non-Preferring Rats with Consecutive Alcohol Training or Acute Alcohol Administration, BRAIN SCIENCES, 2021, 通讯作者
(32) A neural circuit for excessive feeding driven by environmental context in mice, NATURE NEUROSCIENCE, 2021, 第 10 作者
(33) Longitudinal neural connection detection using a ferritin-encoding adeno-associated virus vector and in vivo MRI method, HUMAN BRAIN MAPPING, 2021, 通讯作者
(34) Whole Brain Mapping of Neurons Innervating Extraorbital Lacrimal Glands in Mice and Rats of Both Genders, FRONTIERS IN NEURAL CIRCUITS, 2021, 通讯作者
(35) Correction to:Regional Metabolic Patterns of Abnormal Postoperative Behavioral Performance in Aged Mice Assessed by^1H-NMR Dynamic Mapping Method, Correction to: Regional Metabolic Patterns of Abnormal Postoperative Behavioral Performance in Aged Mice Assessed by 1 H-NMR Dynamic Mapping Method, 神经科学通报:英文版, 2020, 第11作者
(36) Reversal of Social Recognition Deficit in Adult Mice with MECP2 Duplication via Normalization of MeCP2 in the Medial Prefrontal Cortex, Reversal of Social Recognition Deficit in Adult Mice with MECP2 Duplication via Normalization of MeCP2 in the Medial Prefrontal Cortex, NEUROSCIENCE BULLETIN, 2020, 第 10 作者
(37) Cell-Type-Specific Whole-Brain Direct Inputs to the Anterior and Posterior Piriform Cortex, FRONTIERS IN NEURAL CIRCUITS, 2020, 通讯作者
(38) Divergent Projection Patterns Revealed by Reconstruction of Individual Neurons in Orbitofrontal Cortex, Neuroscience Bulletin, 2020, 通讯作者
(39) Qualitative and Quantitative Analysis of Regional Cerebral Free Fatty Acids in Rats Using the Stable Isotope Labeling Liquid Chromatography-Mass Spectrometry Method, MOLECULES, 2020, 通讯作者
(40) Brain control of humoral immune responses amenable to behavioural modulation, NATURE, 2020, 第 10 作者
(41) Regional cerebral metabolic levels and turnover in awake rats after acute or chronic spinal cord injury, FASEB JOURNAL, 2020, 第 10 作者
(42) A mutant vesicular stomatitis virus with reduced cytotoxicity and enhanced anterograde trans-synaptic efficiency, MOLECULAR BRAIN, 2020, 通讯作者
(43) Visuoauditory Associative Memory Established with Cholecystokinin Under Anesthesia Is Retrieved in Behavioral Contexts, JOURNAL OF NEUROSCIENCE, 2020, 第 14 作者
(44) High-brightness anterograde transneuronal HSV1 H129 tracer modified using a Trojan horse-like strategy, MOLECULAR BRAIN, 2020, 通讯作者
(45) In vivo imaging of Zika virus reveals dynamics of viral invasion in immune-sheltered tissues and vertical propagation during pregnancy, THERANOSTICS, 2020, 第11作者
(46) Functions of lactate in the brain of rat with intracerebral hemorrhage evaluated with MRI/MRS and in vitro approaches, CNS NEUROSCIENCE & THERAPEUTICS, 2020, 第 7 作者
(47) Sex-Related Differential Whole-Brain Input Atlas of Locus Coeruleus Noradrenaline Neurons, FRONTIERS IN NEURAL CIRCUITS, 2020, 第 6 作者
(48) Investigation of robust visual reaction and functional connectivity in the rat brain induced by rocuronium bromide with functional MRI, AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2020, 第 9 作者
(49) Rabies Virus Pseudotyped with CVS-N2C Glycoprotein as a Powerful Tool for Retrograde Neuronal Network Tracing, NEUROSCIENCE BULLETIN, 2020, 通讯作者
(50) AAV9-Retro mediates efficient transduction with axon terminal absorption and blood–brain barrier transportation, MOLECULAR BRAIN, 2020, 通讯作者
(51) Biphasic exocytosis of herpesvirus from hippocampal neurons and mechanistic implication to membrane fusion, CELL DISCOVERY, 2020, 第 6 作者
(52) Neuronal mechanisms of adenosine A2A receptors in the loss of consciousness induced by propofol general anesthesia with functional magnetic resonance imaging, J Neurochem, 2020, 第 1 作者
(53) Co-localization of two-color rAAV2-retro confirms the dispersion characteristics of efferent projections of mitral cells in mouse accessory olfactory bulb, Co-localization of two-color rAAV2-retro confirms the dispersion characteristics of efferent projections of mitral cells in mouse accessory olfactory bulb, ZOOLOGICAL RESEARCH, 2020, 通讯作者
(54) ARMBIS: accurate and robust matching of brain image sequences from multiple modal imaging techniques, BIOINFORMATICS, 2019, 第 10 作者
(55) Scalable volumetric imaging for ultrahigh-speed brain mapping at synaptic resolution, National Science Review, 2019, 第 20 作者
(56) Optimization of the Fluorescent Protein Expression Level Based on Pseudorabies Virus Bartha Strain for Neural Circuit Tracing, FRONTIERS IN NEUROANATOMY, 2019, 通讯作者
(57) Glutamatergic Neurons in the Piriform Cortex Influence the Activity of D1- and D2-Type Receptor-Expressing Olfactory Tubercle Neurons, JOURNAL OF NEUROSCIENCE, 2019, 第11作者
(58) A novel cortico-intrathalamic circuit for flight behavior, NATURE NEUROSCIENCE, 2019, 第11作者
(59) Rabies Virus Pseudotyped with CVS-N2C Glycoprotein as a Powerful Tool for Retrograde Neuronal Network Tracing., Neuroscience Bulletin, 2019, 通讯作者
(60) NMR Based Metabolomics Comparison of Different Blood Sampling Techniques in Awake and Anesthetized Rats, MOLECULES, 2019, 第 8 作者
(61) Imaging and Spectral Characteristics of Amyloid Plaque Autofluorescence in Brain Slices from the APP/PS1 Mouse Model of Alzheimer's Disease, Imaging and Spectral Characteristics of Amyloid Plaque Autofluorescence in Brain Slices from the APP/PS1 Mouse Model of Alzheimer's Disease, NEUROSCIENCE BULLETIN, 2019, 通讯作者
(62) Detection of neural connections with ex vivo MRI using a ferritin-encoding trans-synaptic virus, NEUROIMAGE, 2019, 通讯作者
(63) 神经环路示踪工具病毒的研究进展, 分析化学, 2019, 通讯作者
(64) A Visual Circuit Related to Habenula Underlies the Antidepressive Effects of Light Therapy, NEURON, 2019, 第 13 作者
(65) Proteomics Analysis Identifies IRSp53 and Fascin as Critical for PRV Egress and Direct Cell-Cell Transmission, PROTEOMICS, 2019, 通讯作者
(66) Cortical Organization of Centrifugal Afferents to the Olfactory Bulb: Mono- and Trans-synaptic Tracing with Recombinant Neurotropic Viral Tracers, NEUROSCIENCE BULLETIN, 2019, 通讯作者
(67) A VTA GABAergic Neural Circuit Mediates Visually Evoked Innate Defensive Responses, NEURON, 2019, 通讯作者
(68) Regional Metabolic Patterns of Abnormal Postoperative Behavioral Performance in Aged Mice Assessed by 1 H-NMR Dynamic Mapping Method, Neuroscience Bulletin, 2019, 通讯作者
(69) Magneto is ineffective in controlling electrical properties of cerebellar Purkinje cells, IBRO Reports, 2019, 
(70) Evaluation of retrograde labeling profiles of HSV1 H129 anterograde tracer, JOURNAL OF CHEMICAL NEUROANATOMY, 2019, 通讯作者
(71) Development of Versatile and Flexible Sf9 Packaging Cell Line-Dependent OneBac System for Large-Scale Recombinant Adeno-Associated Virus Production, HUMAN GENE THERAPY METHODS, 2019, 
(72) Cholecystokinin release triggered by NMDA receptors produces LTP and sound–sound associative memory, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 第 35 作者
(73) Rostral and Caudal Ventral Tegmental Area GABAergic Inputs to Different Dorsal Raphe Neurons Participate in Opioid Dependence, NEURON, 2019, 第 9 作者
(74) Rapid and Sparse Labeling of Neurons Based on the Mutant Virus-Like Particle of Semliki Forest Virus, NEUROSCIENCE BULLETIN, 2019, 通讯作者
(75) Elevated glutamate, glutamine and GABA levels and reduced taurine level in a schizophrenia model using an in vitro proton nuclear magnetic resonance method, AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2019, 第 6 作者
(76) Quantitative proteomics study of host response to virulent and attenuated pseudorabies virus infection in mouse brain, BBA - Proteins and Proteomics, 2018, 通讯作者
(77) 一种简易的脑片图像的半自动区域划分及细胞计数方法, 波谱学杂志, 2018, 第 7 作者
(78) RTF: a rapid and versatile tissue optical clearing method, SCIENTIFIC REPORTS, 2018, 其他(合作组作者)
(79) Anatomic Evidence for Information Exchange between Primary Afferent Sensory Neurons Innervating the Anterior Eye Chamber and the Dura Mater in Rat, INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2018, 第 8 作者
(80) 利用vsv标记具有特定投射的特异类型神经元的精细结构, 波谱学杂志, 2018, 第 10 作者
(81) A corticopontine circuit for initiation of urination, NATURE NEUROSCIENCE, 2018, 第 17 作者
(82) Activation of parvalbumin interneurons in anterior cingulate cortex impairs observational fear, SCIENCE BULLETIN, 2018, 第 8 作者
(83) A Recombinant Baculovirus Efficiently Generates Recombinant Adeno-Associated Virus Vectors in Cultured Insect Cells and Larvae, MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2018, 通讯作者
(84) Comprehensive Profiling of Fecal Metabolome of Mice by Integrated Chemical Isotope Labeling-Mass Spectrometry Analysis, ANALYTICAL CHEMISTRY, 2018, 其他(合作组作者)
(85) Evaluation of metabolites extraction strategies for identifying different brain regions and their relationship with alcohol preference and gender difference using NMR metabolomics, TALANTA, 2018, 通讯作者
(86) A Mirror-Symmetric Excitatory Link Coordinates Odor Maps across Olfactory Bulbs and Enables Odor Perceptual Unity, NEURON, 2018, 第 6 作者
(87) Schizophrenia-like olfactory dysfunction induced by acute and postnatal phencyclidine exposure in rats, SCHIZOPHRENIA RESEARCH, 2018, 第 8 作者
(88) Stress Accelerates Defensive Responses to Looming in Mice and Involves a Locus Coeruleus-Superior Colliculus Projection, CURRENT BIOLOGY, 2018, 第 16 作者
(89) Different Subgroups of Cholinergic Neurons in the Basal Forebrain Are Distinctly Innervated by the Olfactory Regions and Activated Differentially in Olfactory Memory Retrieval, FRONTIERS IN NEURAL CIRCUITS, 2018, 通讯作者
(90) Zika Virus Attenuation by Codon Pair Deoptimization Induces Sterilizing Immunity in Mouse Models, JOURNAL OF VIROLOGY, 2018, 第11作者
(91) Corticosterone Signaling and a Lateral Habenula–Ventral Tegmental Area Circuit Modulate Compulsive Self-Injurious Behavior in a Rat Model, JOURNAL OF NEUROSCIENCE, 2018, 第11作者
(92) Activity Patterns Elicited by Airflow in the Olfactory Bulb and Their Possible Functions, JOURNAL OF NEUROSCIENCE, 2017, 通讯作者
(93) Activation of the dopaminergic pathway from VTA to the medial olfactory tubercle generates odor-preference and reward, ELIFE, 2017, 通讯作者
(94) A retinoraphe projection regulates serotonergic activity and looming-evoked defensive behavior, Nature Communications, 2017, 第 1 作者
(95) Specific patterns of spinal metabolites underlying α-Me-5-HT-evoked pruritus compared with histamine and capsaicin assessed by proton nuclear magnetic resonance spectroscopy, BBA - Molecular Basis of Disease, 2017, 第 8 作者
(96) Pseudo-typed Semliki Forest virus delivers EGFP into neurons, JOURNAL OF NEUROVIROLOGY, 2017, 第 4 作者
(97) The interhemispheric CA1 circuit governs rapid generalisation but not fear memory, NATURE COMMUNICATIONS, 2017, 第 8 作者
(98) Correcting miR92a-vGAT-Mediated GABAergic Dysfunctions Rescues Human Tau-Induced Anxiety in Mice, MOLECULAR THERAPY, 2017, 第 16 作者
(99) Ablation of TFR1 in Purkinje Cells Inhibits mGlu1 Trafficking and Impairs Motor Coordination, But Not Autistic-Like Behaviors, JOURNAL OF NEUROSCIENCE, 2017, 第 9 作者
(100) NMRSpec: An integrated software package for processing and analyzing one dimensional nuclear magnetic resonance spectra, CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, 2017, 通讯作者
(101) FGF13 Selectively Regulates Heat Nociception by Interacting with Nav1.7, NEURON, 2017, 第11作者
(102) Whole-Brain Mapping of the Inputs and Outputs of the Medial Part of the Olfactory Tubercle, FRONTIERS IN NEURAL CIRCUITS, 2017, 通讯作者
(103) A Central Amygdala-Substantia Innominata Neural Circuitry Encodes Aversive Reinforcement Signals, CELL REPORTS, 2017, 第 8 作者
(104) Chemical reactivation of resin-embedded pHuji adds red for simultaneous two-color imaging with EGFP, BIOMEDICAL OPTICS EXPRESS, 2017, 第 14 作者
(105) Anterograde monosynaptic transneuronal tracers derived from herpes simplex virus 1 strain H129, MOLECULAR NEURODEGENERATION, 2017, 通讯作者
(106) 哺乳动物嗅球的神经网络, The neural circuits of olfactory bulb in mammals, 生命科学, 2017, 第 4 作者
(107) Proteomics and metabolomics analysis of hepatic mitochondrial metabolism in alcohol-preferring and non-preferring rats, ONCOTARGET, 2017, 通讯作者
(108) Reduced GABAergic transmission in the ventrobasal thalamus contributes to thermal hyperalgesia in chronic inflammatory pain (vol 7, 41439, 2017), SCIENTIFIC REPORTS, 2017, 第 8 作者
(109) A single adaptive point mutation in Japanese encephalitis virus capsid is sufficient to render the virus as a stable vector for gene delivery, VIROLOGY, 2016, 通讯作者
(110) Opposite monosynaptic scaling of BLP-vCA1 inputs governs hopefulness- and helplessness-modulated spatial learning and memory, Nature Communications, 2016, 第 21 作者
(111) 小鼠海马下托腹侧向全脑的顺向投射研究, 2016, 
(112) Laterodorsal tegmentum interneuron subtypes oppositely regulate olfactory cue-induced innate fear, NATURE NEUROSCIENCE, 2016, 第 10 作者
(113) Processing of visually evoked innate fear by a non-canonical thalamic pathway, NATURE COMMUNICATIONS, 2015, 第 17 作者
(114) Quantitative proteomics reveals olfactory input-dependent alterations in the mouse olfactory bulb proteome, JOURNAL OF PROTEOMICS, 2014, 通讯作者
(115) Complex relationship between BOLD-fMRI and electrophysiological signals in different olfactory bulb layers, NEUROIMAGE, 2014, 第 5 作者
(116) Deficits of peripheral olfactory inputs reduce cell proliferation in the adult subventricular and subgranular zones, NEUROSCIENCE LETTERS, 2013, 通讯作者
(117) Development- and activity-dependent expression of clusterin in the mouse olfactory bulb, INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE, 2013, 通讯作者
(118) Roles of GSK3 beta in Odor Habituation and Spontaneous Neural Activity of the Mouse Olfactory Bulb, PLOS ONE, 2013, 通讯作者
(119) Numerical Simulation of Airway Dimension Effects on Airflow Patterns and Odorant Deposition Patterns in the Rat Nasal Cavity, PLOS ONE, 2013, 通讯作者
(120) Lateral Entorhinal Modulation of Piriform Cortical Activity and Fine Odor Discrimination, The Journal of Neuroscience, 2013, 第 6 作者
(121) Amyloid-beta Deposition and Olfactory Dysfunction in an Alzheimer's Disease Model, JOURNAL OF ALZHEIMERS DISEASE, 2013, 第 5 作者
(122) Brain-state-independent neural representation of peripheral stimulation in rat olfactory bulb, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 通讯作者
(123) Guanylyl Cyclase-C Modulates Midbrain Dopamine Neurons and its Loss Produces ADHD-like Behavior in Mice, 2011, 通讯作者
(124) State-dependent coherences between the olfactory bulbs for delta and theta oscillations, NEUROSCIENCE LETTERS, 2010, 通讯作者
(125) Application of MRi in the olfactory system of small animals, Advances in Biochemistry and Biophysics, 2009, 通讯作者
(126) Database analyzing and comparing rodent fMRI odor maps, Neuroinformatics, 2007, 第 1 作者
(127) Reproducibility of odor maps by fMRI in rodents, NEUROIMAGE, 2006, 通讯作者
(128) Odor maps of aldehydes and esters revealed by fMRI in the glomerular layer of the mouse olfactory bulb, PNAS, 2003, 第 1 作者
(129) That's your left foot and …, TRENDS IN NEUROSCIENCES, 2001, 
(130) Assessment and discrimination of odor stimuli in rat olfactory bulb by dynamic functional MRI, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 
(131) A Lobster Phospholipase C-β That Associates with G-Proteins in Response to Odorants, The Journal of Neuroscience, 1999, 第 1 作者
(132) A unique urinary constituent, 6-hydroxy-6-methyl-3-heptanone, is a pheromone that accelerates puberty in female mice, CHEMISTRY & BIOLOGY, 1999, 

科研活动

   
科研项目
( 1 ) 嗅觉神经生物学, 负责人, 中国科学院计划, 2008-01--2011-12
( 2 ) 嗅觉系统编码机制, 负责人, 国家任务, 2008-07--2012-06
( 3 ) 标记和研究记忆相关神经环路的新技术新方法, 负责人, 国家任务, 2012-01--2015-12
( 4 ) 嗅觉与饮食状态的关系, 负责人, 国家任务, 2012-01--2015-12
( 5 ) 神经回路示踪及其在感知觉等联结图谱研究中的应用, 负责人, 中国科学院计划, 2012-07--2017-06
( 6 ) 基于荧光层析/CT双模成像的分子影像关键技术研究, 参与, 国家任务, 2012-01--2014-12
( 7 ) 伪狂犬病毒跨突触传输机制的研究, 参与, 国家任务, 2014-01--2017-12
( 8 ) 灵长类神经回路精细结构成像的新方法和新工具, 负责人, 国家任务, 2015-01--2019-08
( 9 ) 神经环路示踪技术平台, 参与, 国家任务, 2014-01--2015-12
( 10 ) 面向情感和记忆神经环路图谱的荧光标记策略研究, 参与, 国家任务, 2015-01--2017-12
( 11 ) “窝/安全空间”记忆形成及其调控恐惧反应的环路机制, 负责人, 国家任务, 2017-01--2019-12
( 12 ) 气味相关的两个大脑半球之间的联系, 负责人, 国家任务, 2016-10--2019-09
( 13 ) 腹侧被盖区-嗅结节多巴胺能通路在气味偏好形成中的作用, 负责人, 国家任务, 2018-01--2021-12
( 14 ) 全脑尺度神经环路快速三维显微成像与数据处理新技术, 参与, 国家任务, 2018-01--2019-12
( 15 ) 介观层次脑功能连接组学研究的新技术和新方法, 负责人, 国家任务, 2019-01--2023-12
( 16 ) 脑联接图谱绘制新技术, 负责人, 中国科学院计划, 2018-06--2023-05
( 17 ) 生命波谱与成像, 参与, 国家任务, 2020-01--2024-12
( 18 ) 跨物种、特定类型神经元及环路研究的工具开发及应用, 负责人, 国家任务, 2022-01--2025-12
( 19 ) 脑功能环路研究的新技术方法和工具的研发与转化, 参与, 地方任务, 2019-01--2021-12
( 20 ) rAAV病毒载体制剂质量评估技术研究, 负责人, 地方任务, 2022-01--2023-12
( 21 ) 全脑介观神经联接图谱绘制技术平台(子课题3:神经环路标记技术分平台), 负责人, 国家任务, 2021-12--2026-11
( 22 ) 生物医药病毒载体的研发、评价、转化、产业化与商业化, 负责人, 国家任务, 2021-01--2022-12
( 23 ) 深圳市生物医药病毒载体重点实验室, 负责人, 地方任务, 2021-03--2023-03
( 24 ) 中国科学院脑联结解析与调控重点实验室, 参与, 中国科学院计划, 2019-11--2024-11
( 25 ) 感觉系统神经生物学, 负责人, 国家任务, 2008-01--2011-12
( 26 ) 生物核磁共振波谱学, 参与, 国家任务, 2010-01--2015-12

指导学生

已指导学生

李安安  博士研究生  070208-无线电物理  

何晓斌  博士研究生  070208-无线电物理  

饶小平  博士研究生  070208-无线电物理  

李湘  硕士研究生  070208-无线电物理  

刘飞  硕士研究生  070302-分析化学  

李博  博士研究生  070208-无线电物理  

刘青  博士研究生  070208-无线电物理  

高运苓  博士研究生  070302-分析化学  

许智祥  博士研究生  070302-分析化学  

龚玲  博士研究生  070208-无线电物理  

吴瑞琪  博士研究生  070208-无线电物理  

王莉  硕士研究生  070302-分析化学  

陈荣祥  博士研究生  070302-分析化学  

郑英伟  博士研究生  070302-分析化学  

靳森  博士研究生  070302-分析化学  

朱续涛  博士研究生  070302-分析化学  

郑宁  博士研究生  070302-分析化学  

文鹏杰  硕士研究生  085238-生物工程  

钟鑫  硕士研究生  070304-物理化学  

胡婷  博士研究生  070302-分析化学  

韩增鹏  硕士研究生  085238-生物工程  

现指导学生

文鹏杰  博士研究生  070302-分析化学  

施祥玮  博士研究生  070302-分析化学  

应敏  博士研究生  070302-分析化学  

刘晶晶  博士研究生  071006-神经生物学  

邱宇翔  硕士研究生  071000-生物学  

朱珍香  博士研究生  070300-化学  

韩增鹏  博士研究生  070302-分析化学