基本信息

熊霞 女 中国科学院亚热带农业生态研究所
电子邮件: xx@isa.ac.cn
通信地址: 湖南省长沙市芙蓉区远大二路644号
邮政编码:
电子邮件: xx@isa.ac.cn
通信地址: 湖南省长沙市芙蓉区远大二路644号
邮政编码:
研究领域
主要研究围绕仔猪肠道健康及其模型构建、母子营养一体化研究展开。主要研究结果如下:1)阐明了断奶仔猪肠道隐窝-绒毛轴结构发育和分化特性及其适应性变化规律;2)阐明了氨基酸或溶菌酶和聚糖等替抗产品对猪生长和肠道健康的调控机制;3)建立肠道类器官研究平台;4)基于仔猪模型进行婴幼儿营养配方奶粉的营养评价;4)基于母子一体化研究了母猪营养及其对仔猪健康的影响。
招生信息
招生专业
090502-动物营养与饲料科学
招生方向
仔猪,营养调控
教育背景
2002-09--2010-01 湖南师范大学 博士
1998-09--2002-05 湖南师范大学 学士
1998-09--2002-05 湖南师范大学 学士
学历
工作经历
工作简历
2022-01~2024-05,中国科学院亚热带农业生态研究所, 研究员
2016-06~2017-06,加州大学-戴维斯分校, 访问学者
2015-01~2021-12,中国科学院亚热带农业生态研究所, 副研究员
2010-10~2014-12,中国科学院亚热带农业生态研究所, 助理研究员
2016-06~2017-06,加州大学-戴维斯分校, 访问学者
2015-01~2021-12,中国科学院亚热带农业生态研究所, 副研究员
2010-10~2014-12,中国科学院亚热带农业生态研究所, 助理研究员
专利与奖励
奖励信息
(1) 颐和青年创新奖, 其他, 2022
(2) 神农中华农业科技奖优秀创新团队奖, 一等奖, 国家级, 2020
(2) 神农中华农业科技奖优秀创新团队奖, 一等奖, 国家级, 2020
专利成果
( 1 ) 一种提高产蛋后期蛋鸡生产性能的中药组合物及制备方法和应用, 发明专利, 2022, 第 6 作者, 专利号: CN115192636A
( 2 ) 一种用于猪胎盘滋养层类器官培养的分子培养基, 发明专利, 2021, 第 3 作者, 专利号: CN113862219A
( 3 ) 一种猪胃底腺干细胞分离及三维类器官培养方法, 发明专利, 2021, 第 2 作者, 专利号: CN112608885A
( 4 ) 一种猪肝脾脏导管干细胞分离及三维类器官培养方法, 发明专利, 2021, 第 2 作者, 专利号: CN112538457A
( 5 ) 一种用于猪小肠类器官培养的分子培养基, 发明专利, 2021, 第 1 作者, 专利号: CN112501111A
( 6 ) 一种绿色无抗低重金属排放的仔猪预混料饲料添加剂及制备方法, 发明专利, 2020, 第 4 作者, 专利号: CN111838415A
( 7 ) 一种改善肠功能的添加剂及其制备的预混料, 发明专利, 2019, 第 3 作者, 专利号: CN110179001A
( 8 ) 一种调节肠道上皮细胞和肠道发育的仔猪教槽料, 发明专利, 2019, 第 4 作者, 专利号: CN110200162A
( 9 ) 一种低重金属排放的无抗全价仔猪配合饲料及制备方法和应用, 发明专利, 2019, 第 3 作者, 专利号: CN109997976A
( 10 ) 一种断奶仔猪无抗生素全价配合饲料及制备方法和应用, 发明专利, 2019, 第 1 作者, 专利号: CN110150500A
( 11 ) 新生哺乳动物饲养系统, 实用新型, 2016, 第 6 作者, 专利号: CN205124663U
( 12 ) 一种袋装厌氧发酵方法, 发明专利, 2015, 第 9 作者, 专利号: CN104855687A
( 13 ) 一种饲料添加剂一乙醇胺的制备方法及应用, 发明专利, 2013, 第 2 作者, 专利号: CN103271238A
( 14 ) 一种分离乳酸杆菌的方法, 发明专利, 2013, 第 4 作者, 专利号: CN103045523A
( 2 ) 一种用于猪胎盘滋养层类器官培养的分子培养基, 发明专利, 2021, 第 3 作者, 专利号: CN113862219A
( 3 ) 一种猪胃底腺干细胞分离及三维类器官培养方法, 发明专利, 2021, 第 2 作者, 专利号: CN112608885A
( 4 ) 一种猪肝脾脏导管干细胞分离及三维类器官培养方法, 发明专利, 2021, 第 2 作者, 专利号: CN112538457A
( 5 ) 一种用于猪小肠类器官培养的分子培养基, 发明专利, 2021, 第 1 作者, 专利号: CN112501111A
( 6 ) 一种绿色无抗低重金属排放的仔猪预混料饲料添加剂及制备方法, 发明专利, 2020, 第 4 作者, 专利号: CN111838415A
( 7 ) 一种改善肠功能的添加剂及其制备的预混料, 发明专利, 2019, 第 3 作者, 专利号: CN110179001A
( 8 ) 一种调节肠道上皮细胞和肠道发育的仔猪教槽料, 发明专利, 2019, 第 4 作者, 专利号: CN110200162A
( 9 ) 一种低重金属排放的无抗全价仔猪配合饲料及制备方法和应用, 发明专利, 2019, 第 3 作者, 专利号: CN109997976A
( 10 ) 一种断奶仔猪无抗生素全价配合饲料及制备方法和应用, 发明专利, 2019, 第 1 作者, 专利号: CN110150500A
( 11 ) 新生哺乳动物饲养系统, 实用新型, 2016, 第 6 作者, 专利号: CN205124663U
( 12 ) 一种袋装厌氧发酵方法, 发明专利, 2015, 第 9 作者, 专利号: CN104855687A
( 13 ) 一种饲料添加剂一乙醇胺的制备方法及应用, 发明专利, 2013, 第 2 作者, 专利号: CN103271238A
( 14 ) 一种分离乳酸杆菌的方法, 发明专利, 2013, 第 4 作者, 专利号: CN103045523A
出版信息
发表论文
(1) Effect of riboflavin on intestinal development and intestinal epithelial cell function of weaned piglets, JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION, 2023, 第 3 作者
(2) Peppermint extract improves egg production and quality, increases antioxidant capacity, and alters cecal microbiota in late-phase laying hens, FRONTIERS IN MICROBIOLOGY, 2023, 第 6 作者
(3) Effect of riboflavin on intestinal development and intestinal epithelial cell function of weaned piglets, JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION, 2022, 第 3 作者
(4) Early weaning leads to the remodeling of lipid profile in piglet jejunal crypt cells during post-weaning days, Early weaning leads to the remodeling of lipid profile in piglet jejunal crypt cells during post-weaning days, 动物营养:英文版, 2022, 第 2 作者 通讯作者
(5) A water-soluble β-glucan improve growth performance by altering gut microbiome and health in weaned pigs, Animal Nutrition, 2021, 第 2 作者 通讯作者
(6) Dietary L-glutamine supplementation modulates microbial community and activates innate immunity in the mouse intestine (vol 46, pg 2403, 2014), AMINO ACIDS, 2021, 第 6 作者 通讯作者
(7) 酵母多糖对断奶仔猪生长性能、肠道形态和肠道免疫状态的影响, Effects of Yeast Polysaccharide on Growth Performance,Intestinal Morphology and Intestinal Immune Status of Weaned Piglets, 动物营养学报, 2021, 第 4 作者
(8) Effects of stocking density on growth performance, blood parameters and immunity of growing pigs, Effects of stocking density on growth performance, blood parameters and immunity of growing pigs, 动物营养:英文版, 2020, 第 2 作者 通讯作者
(9) Organic selenium supplement partially alleviated diquat-induced oxidative insults and hepatic metabolic stress in nursery pigs, BRITISH JOURNAL OF NUTRITION, 2020, 第 3 作者
(10) Effect of glucose, soya oil and glutamine on protein expression and mammalian target of rapamycin complex 1 pathway of jejunal crypt enterocytes in weaned piglets, BRITISH JOURNAL OF NUTRITION, 2020, 第 1 作者
(11) Nutritional Intervention for the Intestinal Development and Health of Weaned Pigs, FRONTIERS IN VETERINARY SCIENCE, 2019, 第 1 作者
(12) Identification of microRNA transcriptome reveals that miR-100 is involved in the renewal of porcine intestinal epithelial cells, SCIENCE CHINA. LIFE SCIENCES, 2019, 第 2 作者 通讯作者
(13) Effects of dietary lysozyme levels on growth performance, intestinal morphology, immunity response and microbiota community of growing pigs, JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2019, 第 2 作者 通讯作者
(14) Dietary Lysozyme Alters Sow's Gut Microbiota, Serum Immunity and Milk Metabolite Profile, FRONTIERS IN MICROBIOLOGY, 2019, 第 2 作者 通讯作者
(15) Effects of dietary supplementation with epidermal growth factor on nutrient digestibility, intestinal development and expression of nutrient transporters in early-weaned piglets, JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION, 2019, 第 7 作者
(16) Effects of dietary glucan on intestinal morphology, immunity response, barrier function and antioxidant capacity in weaning pigs, JOURNAL OF ANIMAL SCIENCE, 2019, 第 1 作者
(17) Identification of microRNA transcriptome reveals that miR-100 is involved in the renewal of porcine intestinal epithelial cells, Identification of microRNA transcriptome reveals that miR-100 is involved in the renewal of porcine intestinal epithelial cells, 中国科学:生命科学英文版, 2019, 第 2 作者
(18) Dietary lysozyme supplementation contributes to enhanced intestinal functions and gut microflora of piglets, FOOD & FUNCTION, 2019, 第 1 作者
(19) Rapid Communication: The relationship of enterocyte proliferation with intestinal morphology and nutrient digestibility in weaning piglets, JOURNAL OF ANIMAL SCIENCE, 2019, 第 7 作者
(20) Effect of dietary soy oil, glucose, and glutamine on growth performance, amino acid profile, blood profile, immunity, and antioxidant capacity in weaned piglets, SCIENCE CHINA-LIFE SCIENCES, 2018, 第 2 作者 通讯作者
(21) The effects of dietary sulfur amino acids on growth performance, intestinal morphology, enzyme activity, and nutrient transporters in weaning piglets, JOURNAL OF ANIMAL SCIENCE, 2018, 第 7 作者
(22) Dietary sulfur amino acids affect jejunal cell proliferation and functions by affecting antioxidant capacity, Wnt/beta-catenin, and the mechanistic target of rapamycin signaling pathways in weaning piglets, JOURNAL OF ANIMAL SCIENCE, 2018, 第 8 作者
(23) Ethanolamine enhances intestinal functions by altering gut microbiome and mucosal anti-stress capacity in weaned rats, BRITISH JOURNAL OF NUTRITION, 2018, 第 2 作者 通讯作者
(24) miRNAs对动物肠道健康的调控作用, The Role of miRNAs in Regulation of Animal Intestinal Health, 生命科学研究, 2018, 第 3 作者
(25) Suckling Piglet Intestinal Enterocyte Nutrient Metabolism Changes, CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018, 第 2 作者
(26) Energy metabolism in the intestinal crypt epithelial cells of piglets during the suckling period, SCIENTIFIC REPORTS, 2018, 第 2 作者
(27) Expression of proteins in intestinal middle villus epithelial cells of weaning piglets, FRONTIERS IN BIOSCIENCE-LANDMARK, 2017, 第 2 作者
(28) Molecular cloning, characterization and expression analysis of Frizzled 6 in the small intestine of pigs ( Sus scrofa ), PLOS ONE, 2017, 第 5 作者 通讯作者
(29) 肠道隐窝-绒毛轴上皮细胞更新及调控机制研究进展, Current advances in renewal mechanisms of intestinal epithelial cells along the crypt-villus axis, 中国科学(生命科学), 2017, 第 2 作者
(30) Effects of Lysine deficiency and Lys-Lys dipeptide on cellular apoptosis and amino acids metabolism, MOLECULAR NUTRITION & FOOD RESEARCH, 2017, 第 13 作者
(31) Improving agricultural straw preparation logistics stream in bio-methane production: experimental studies and application analysis, 3 BIOTECH, 2017, 第 6 作者
(32) Toxicity assessment of hydrogen peroxide on Toll-like receptor system, apoptosis, and mitochondrial respiration in piglets and IPEC-J2 cells, ONCOTARGET, 2017, 第 10 作者
(33) Effects of weaning on intestinal crypt epithelial cells in piglets, SCIENTIFIC REPORTS, 2016, 第 2 作者
(34) Ethanolamine enhances the proliferation of intestinal epithelial cells via the mTOR signaling pathway and mitochondrial function, IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 2016, 第 2 作者
(35) Effects of yeast products on the intestinal morphology, barrier function, cytokine expression, and antioxidant system of weaned piglets *, JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B, 2016, 第 5 作者 通讯作者
(36) Differential proteome analysis along jejunal crypt-villus axis in piglets, FRONTIERS IN BIOSCIENCE-LANDMARK, 2016, 第 1 作者
(37) Metabolomic analysis of intestinal epithelial cell maturation along the crypt-villus axis, RSC ADVANCES, 2016, 第 2 作者
(38) 应激和某些疾病状态下猪肠道差异蛋白质表达的研究进展, Research Advances on Intestinal Differential Protein Expression of Pigs under Stress and Some Diseases, 动物营养学报, 2016, 第 2 作者
(39) 含硫氨基酸对猪生长性能及肠道功能的影响机制, The Effects and Mechanisms of Sulfur Amino Acids on Growth Performance and Intestinal Function in Pigs, 生命科学研究, 2016, 第 2 作者
(40) 谷氨酰胺对断奶仔猪肠黏膜更新的影响及其机制, Mechanism and Effects of Glutamine on Intestinal Mucosa Regeneration of Weaned Piglets, 动物营养学报, 2016, 第 3 作者
(41) Energy metabolism in intestinal epithelial cells during maturation along the crypt-villus axis, SCIENTIFIC REPORTS, 2016, 第 3 作者 通讯作者
(42) Developmental changes in intercellular junctions and Kv channels in the intestine of piglets during the suckling and post-weaning periods, Developmental changes in intercellular junctions and Kv channels in the intestine of piglets during the suckling and post-weaning periods, 畜牧与生物技术杂志:英文版, 2016, 第 6 作者
(43) Mammalian Target of Rapamycin Signaling Pathway Changes with Intestinal Epithelial Cells Renewal Along Crypt-Villus Axis, CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2016, 第 2 作者
(44) The application of antimicrobial peptides as growth and health promoters for swine, The application of antimicrobial peptides as growth and health promoters for swine, 畜牧与生物技术杂志:英文版, 2016, 第 5 作者
(45) Effects of Weaning on Intestinal Upper Villus Epithelial Cells of Piglets, PLOS ONE, 2016, 第 2 作者
(46) Dietary Chitosan Supplementation Increases Microbial Diversity and Attenuates the Severity of Citrobacter rodentium Infection in Mice, MEDIATORS OF INFLAMMATION, 2016, 第 5 作者
(47) 乳源生物活性肽对动物肠道功能的影响及作用机制, Mechanisms and Effects of Milk-Derived Bioactive Peptides on Intestinal Functions of Animals, 动物营养学报, 2016, 第 2 作者
(48) Developmental changes in intercellular junctions and Kv channels in the intestine of piglets during the suckling and post-weaning periods, JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY, 2016, 第 6 作者
(49) Effect of low dosage of chito-oligosaccharide supplementation on intestinal morphology, immune response, antioxidant capacity, and barrier function in weaned piglets, JOURNAL OF ANIMAL SCIENCE, 2015,
(50) Effects of dietary protein/energy ratio on growth performance, carcass trait, meat quality, and plasma metabolites in pigs of different genotypes, JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY, 2015, 第 8 作者
(51) Differential expression of proteins involved in energy production along the crypt-villus axis in early-weaning pig small intestine, AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2015, 第 1 作者
(52) L-Arginine improves DNA synthesis in LPS-challenged enterocytes, FRONTIERS IN BIOSCIENCE-LANDMARK, 2015, 第 3 作者
(53) Effects of dietary protein, JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY, 2015, 第 8 作者
(54) Protective effect of dietary L-arginine against enterotoxigenic Escherichia coli infection in mice, AMINO ACIDS, 2015, 第 4 作者
(55) The application of antimicrobial peptides as growth and health promoters for swine, JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY, 2015, 第 5 作者
(56) Methionine deficiency reduces autophagy and accelerates death in intestinal epithelial cells infected with enterotoxigenic Escherichia coli, AMINO ACIDS, 2015, 第 3 作者 通讯作者
(57) Alanyl-glutamine but not glycyl-glutamine improved the proliferation of enterocytes as glutamine substitution in vitro, AMINO ACIDS, 2015, 第 4 作者
(58) 腐胺和脯氨酸对哺乳期仔猪空肠绒毛-隐窝轴上皮细胞的多胺代谢及Wnt信号通路的影响, Impact of Putrescine and Proline on Suckling Piglet Jejunum Villus - crypt Axis Epithelial Polyamine Metabolism and Wnt Signal Pathway, 中国农业科学, 2015, 第 2 作者
(59) Therapeutic Effects of Glutamic Acid in Piglets Challenged with Deoxynivalenol, PLOS ONE, 2014, 第 9 作者 通讯作者
(60) 外源多胺对断奶仔猪肠道结构和功能的作用及机制, Exogenous Polyamine: Effects on Intestinal Structure and Function in Piglet and Its Mechanism, 动物营养学报, 2014, 第 2 作者
(61) Therapeutic Effects of Glutamic Acid in Piglets Challenged with Deoxynivalenol, PLOS ONE, 2014, 第 9 作者 通讯作者
(62) An NMR-Based Metabolomic Approach to Investigate the Effects of Supplementation with Glutamic Acid in Piglets Challenged with Deoxynivalenol, PLOS ONE, 2014, 第 9 作者 通讯作者
(63) 脱氧雪腐镰刀菌烯醇对肠道屏障的影响及其作用机制, Effects of Deoxynivalenol on Intestinal Barrier and Its Mechanisms, 动物营养学报, 2013, 第 1 作者
(64) 肠道与微生物相互作用体外研究模型进展与应用, Advances and Applications of in Vitro Models for Host-Microbe Interactions Research, 动物营养学报, 2013, 第 3 作者
(65) Soy isoflavones modulate adipokines and myokines to regulate lipid metabolism in adipose tissue, skeletal muscle and liver of male Huanjiang mini-pigs, MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2013, 第 3 作者
(66) L-Arginine stimulates DNA synthesis and reduces LPS-induced DNA damage in porcine intestine epithelial cells, AMINO ACIDS, 2013, 第 2 作者
(67) Molecular cloning, distribution, and ontogenetic expression of the amino acid transreceptor SNAT2 mRNA in the small intestine of piglets, AMINO ACIDS, 2013, 第 4 作者
(68) 质谱技术在氨基酸分析方法中的应用, Application of Mass Spectrometry in Amino Acids Analysis, 食品与生物技术学报, 2012, 第 1 作者
(69) 肠道氨基酸及氨基酸转运载体研究进展, 生理科学进展, 2012, 第 1 作者
(70) Integrative application of sequential digestion and elution to the membrane proteome analysis of rat hippocampal cells, AMINO ACIDS, 2011, 第 1 作者
(2) Peppermint extract improves egg production and quality, increases antioxidant capacity, and alters cecal microbiota in late-phase laying hens, FRONTIERS IN MICROBIOLOGY, 2023, 第 6 作者
(3) Effect of riboflavin on intestinal development and intestinal epithelial cell function of weaned piglets, JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION, 2022, 第 3 作者
(4) Early weaning leads to the remodeling of lipid profile in piglet jejunal crypt cells during post-weaning days, Early weaning leads to the remodeling of lipid profile in piglet jejunal crypt cells during post-weaning days, 动物营养:英文版, 2022, 第 2 作者 通讯作者
(5) A water-soluble β-glucan improve growth performance by altering gut microbiome and health in weaned pigs, Animal Nutrition, 2021, 第 2 作者 通讯作者
(6) Dietary L-glutamine supplementation modulates microbial community and activates innate immunity in the mouse intestine (vol 46, pg 2403, 2014), AMINO ACIDS, 2021, 第 6 作者 通讯作者
(7) 酵母多糖对断奶仔猪生长性能、肠道形态和肠道免疫状态的影响, Effects of Yeast Polysaccharide on Growth Performance,Intestinal Morphology and Intestinal Immune Status of Weaned Piglets, 动物营养学报, 2021, 第 4 作者
(8) Effects of stocking density on growth performance, blood parameters and immunity of growing pigs, Effects of stocking density on growth performance, blood parameters and immunity of growing pigs, 动物营养:英文版, 2020, 第 2 作者 通讯作者
(9) Organic selenium supplement partially alleviated diquat-induced oxidative insults and hepatic metabolic stress in nursery pigs, BRITISH JOURNAL OF NUTRITION, 2020, 第 3 作者
(10) Effect of glucose, soya oil and glutamine on protein expression and mammalian target of rapamycin complex 1 pathway of jejunal crypt enterocytes in weaned piglets, BRITISH JOURNAL OF NUTRITION, 2020, 第 1 作者
(11) Nutritional Intervention for the Intestinal Development and Health of Weaned Pigs, FRONTIERS IN VETERINARY SCIENCE, 2019, 第 1 作者
(12) Identification of microRNA transcriptome reveals that miR-100 is involved in the renewal of porcine intestinal epithelial cells, SCIENCE CHINA. LIFE SCIENCES, 2019, 第 2 作者 通讯作者
(13) Effects of dietary lysozyme levels on growth performance, intestinal morphology, immunity response and microbiota community of growing pigs, JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2019, 第 2 作者 通讯作者
(14) Dietary Lysozyme Alters Sow's Gut Microbiota, Serum Immunity and Milk Metabolite Profile, FRONTIERS IN MICROBIOLOGY, 2019, 第 2 作者 通讯作者
(15) Effects of dietary supplementation with epidermal growth factor on nutrient digestibility, intestinal development and expression of nutrient transporters in early-weaned piglets, JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION, 2019, 第 7 作者
(16) Effects of dietary glucan on intestinal morphology, immunity response, barrier function and antioxidant capacity in weaning pigs, JOURNAL OF ANIMAL SCIENCE, 2019, 第 1 作者
(17) Identification of microRNA transcriptome reveals that miR-100 is involved in the renewal of porcine intestinal epithelial cells, Identification of microRNA transcriptome reveals that miR-100 is involved in the renewal of porcine intestinal epithelial cells, 中国科学:生命科学英文版, 2019, 第 2 作者
(18) Dietary lysozyme supplementation contributes to enhanced intestinal functions and gut microflora of piglets, FOOD & FUNCTION, 2019, 第 1 作者
(19) Rapid Communication: The relationship of enterocyte proliferation with intestinal morphology and nutrient digestibility in weaning piglets, JOURNAL OF ANIMAL SCIENCE, 2019, 第 7 作者
(20) Effect of dietary soy oil, glucose, and glutamine on growth performance, amino acid profile, blood profile, immunity, and antioxidant capacity in weaned piglets, SCIENCE CHINA-LIFE SCIENCES, 2018, 第 2 作者 通讯作者
(21) The effects of dietary sulfur amino acids on growth performance, intestinal morphology, enzyme activity, and nutrient transporters in weaning piglets, JOURNAL OF ANIMAL SCIENCE, 2018, 第 7 作者
(22) Dietary sulfur amino acids affect jejunal cell proliferation and functions by affecting antioxidant capacity, Wnt/beta-catenin, and the mechanistic target of rapamycin signaling pathways in weaning piglets, JOURNAL OF ANIMAL SCIENCE, 2018, 第 8 作者
(23) Ethanolamine enhances intestinal functions by altering gut microbiome and mucosal anti-stress capacity in weaned rats, BRITISH JOURNAL OF NUTRITION, 2018, 第 2 作者 通讯作者
(24) miRNAs对动物肠道健康的调控作用, The Role of miRNAs in Regulation of Animal Intestinal Health, 生命科学研究, 2018, 第 3 作者
(25) Suckling Piglet Intestinal Enterocyte Nutrient Metabolism Changes, CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018, 第 2 作者
(26) Energy metabolism in the intestinal crypt epithelial cells of piglets during the suckling period, SCIENTIFIC REPORTS, 2018, 第 2 作者
(27) Expression of proteins in intestinal middle villus epithelial cells of weaning piglets, FRONTIERS IN BIOSCIENCE-LANDMARK, 2017, 第 2 作者
(28) Molecular cloning, characterization and expression analysis of Frizzled 6 in the small intestine of pigs ( Sus scrofa ), PLOS ONE, 2017, 第 5 作者 通讯作者
(29) 肠道隐窝-绒毛轴上皮细胞更新及调控机制研究进展, Current advances in renewal mechanisms of intestinal epithelial cells along the crypt-villus axis, 中国科学(生命科学), 2017, 第 2 作者
(30) Effects of Lysine deficiency and Lys-Lys dipeptide on cellular apoptosis and amino acids metabolism, MOLECULAR NUTRITION & FOOD RESEARCH, 2017, 第 13 作者
(31) Improving agricultural straw preparation logistics stream in bio-methane production: experimental studies and application analysis, 3 BIOTECH, 2017, 第 6 作者
(32) Toxicity assessment of hydrogen peroxide on Toll-like receptor system, apoptosis, and mitochondrial respiration in piglets and IPEC-J2 cells, ONCOTARGET, 2017, 第 10 作者
(33) Effects of weaning on intestinal crypt epithelial cells in piglets, SCIENTIFIC REPORTS, 2016, 第 2 作者
(34) Ethanolamine enhances the proliferation of intestinal epithelial cells via the mTOR signaling pathway and mitochondrial function, IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 2016, 第 2 作者
(35) Effects of yeast products on the intestinal morphology, barrier function, cytokine expression, and antioxidant system of weaned piglets *, JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B, 2016, 第 5 作者 通讯作者
(36) Differential proteome analysis along jejunal crypt-villus axis in piglets, FRONTIERS IN BIOSCIENCE-LANDMARK, 2016, 第 1 作者
(37) Metabolomic analysis of intestinal epithelial cell maturation along the crypt-villus axis, RSC ADVANCES, 2016, 第 2 作者
(38) 应激和某些疾病状态下猪肠道差异蛋白质表达的研究进展, Research Advances on Intestinal Differential Protein Expression of Pigs under Stress and Some Diseases, 动物营养学报, 2016, 第 2 作者
(39) 含硫氨基酸对猪生长性能及肠道功能的影响机制, The Effects and Mechanisms of Sulfur Amino Acids on Growth Performance and Intestinal Function in Pigs, 生命科学研究, 2016, 第 2 作者
(40) 谷氨酰胺对断奶仔猪肠黏膜更新的影响及其机制, Mechanism and Effects of Glutamine on Intestinal Mucosa Regeneration of Weaned Piglets, 动物营养学报, 2016, 第 3 作者
(41) Energy metabolism in intestinal epithelial cells during maturation along the crypt-villus axis, SCIENTIFIC REPORTS, 2016, 第 3 作者 通讯作者
(42) Developmental changes in intercellular junctions and Kv channels in the intestine of piglets during the suckling and post-weaning periods, Developmental changes in intercellular junctions and Kv channels in the intestine of piglets during the suckling and post-weaning periods, 畜牧与生物技术杂志:英文版, 2016, 第 6 作者
(43) Mammalian Target of Rapamycin Signaling Pathway Changes with Intestinal Epithelial Cells Renewal Along Crypt-Villus Axis, CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2016, 第 2 作者
(44) The application of antimicrobial peptides as growth and health promoters for swine, The application of antimicrobial peptides as growth and health promoters for swine, 畜牧与生物技术杂志:英文版, 2016, 第 5 作者
(45) Effects of Weaning on Intestinal Upper Villus Epithelial Cells of Piglets, PLOS ONE, 2016, 第 2 作者
(46) Dietary Chitosan Supplementation Increases Microbial Diversity and Attenuates the Severity of Citrobacter rodentium Infection in Mice, MEDIATORS OF INFLAMMATION, 2016, 第 5 作者
(47) 乳源生物活性肽对动物肠道功能的影响及作用机制, Mechanisms and Effects of Milk-Derived Bioactive Peptides on Intestinal Functions of Animals, 动物营养学报, 2016, 第 2 作者
(48) Developmental changes in intercellular junctions and Kv channels in the intestine of piglets during the suckling and post-weaning periods, JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY, 2016, 第 6 作者
(49) Effect of low dosage of chito-oligosaccharide supplementation on intestinal morphology, immune response, antioxidant capacity, and barrier function in weaned piglets, JOURNAL OF ANIMAL SCIENCE, 2015,
(50) Effects of dietary protein/energy ratio on growth performance, carcass trait, meat quality, and plasma metabolites in pigs of different genotypes, JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY, 2015, 第 8 作者
(51) Differential expression of proteins involved in energy production along the crypt-villus axis in early-weaning pig small intestine, AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2015, 第 1 作者
(52) L-Arginine improves DNA synthesis in LPS-challenged enterocytes, FRONTIERS IN BIOSCIENCE-LANDMARK, 2015, 第 3 作者
(53) Effects of dietary protein, JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY, 2015, 第 8 作者
(54) Protective effect of dietary L-arginine against enterotoxigenic Escherichia coli infection in mice, AMINO ACIDS, 2015, 第 4 作者
(55) The application of antimicrobial peptides as growth and health promoters for swine, JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY, 2015, 第 5 作者
(56) Methionine deficiency reduces autophagy and accelerates death in intestinal epithelial cells infected with enterotoxigenic Escherichia coli, AMINO ACIDS, 2015, 第 3 作者 通讯作者
(57) Alanyl-glutamine but not glycyl-glutamine improved the proliferation of enterocytes as glutamine substitution in vitro, AMINO ACIDS, 2015, 第 4 作者
(58) 腐胺和脯氨酸对哺乳期仔猪空肠绒毛-隐窝轴上皮细胞的多胺代谢及Wnt信号通路的影响, Impact of Putrescine and Proline on Suckling Piglet Jejunum Villus - crypt Axis Epithelial Polyamine Metabolism and Wnt Signal Pathway, 中国农业科学, 2015, 第 2 作者
(59) Therapeutic Effects of Glutamic Acid in Piglets Challenged with Deoxynivalenol, PLOS ONE, 2014, 第 9 作者 通讯作者
(60) 外源多胺对断奶仔猪肠道结构和功能的作用及机制, Exogenous Polyamine: Effects on Intestinal Structure and Function in Piglet and Its Mechanism, 动物营养学报, 2014, 第 2 作者
(61) Therapeutic Effects of Glutamic Acid in Piglets Challenged with Deoxynivalenol, PLOS ONE, 2014, 第 9 作者 通讯作者
(62) An NMR-Based Metabolomic Approach to Investigate the Effects of Supplementation with Glutamic Acid in Piglets Challenged with Deoxynivalenol, PLOS ONE, 2014, 第 9 作者 通讯作者
(63) 脱氧雪腐镰刀菌烯醇对肠道屏障的影响及其作用机制, Effects of Deoxynivalenol on Intestinal Barrier and Its Mechanisms, 动物营养学报, 2013, 第 1 作者
(64) 肠道与微生物相互作用体外研究模型进展与应用, Advances and Applications of in Vitro Models for Host-Microbe Interactions Research, 动物营养学报, 2013, 第 3 作者
(65) Soy isoflavones modulate adipokines and myokines to regulate lipid metabolism in adipose tissue, skeletal muscle and liver of male Huanjiang mini-pigs, MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2013, 第 3 作者
(66) L-Arginine stimulates DNA synthesis and reduces LPS-induced DNA damage in porcine intestine epithelial cells, AMINO ACIDS, 2013, 第 2 作者
(67) Molecular cloning, distribution, and ontogenetic expression of the amino acid transreceptor SNAT2 mRNA in the small intestine of piglets, AMINO ACIDS, 2013, 第 4 作者
(68) 质谱技术在氨基酸分析方法中的应用, Application of Mass Spectrometry in Amino Acids Analysis, 食品与生物技术学报, 2012, 第 1 作者
(69) 肠道氨基酸及氨基酸转运载体研究进展, 生理科学进展, 2012, 第 1 作者
(70) Integrative application of sequential digestion and elution to the membrane proteome analysis of rat hippocampal cells, AMINO ACIDS, 2011, 第 1 作者
科研活动
科研项目
( 1 ) L-β-半乳葡聚糖在断奶仔猪上的应用研究, 负责人, 境内委托项目, 2024-10--2024-10
( 2 ) 猪饲粮养分高效协同利用的营养代谢基础, 负责人, 国家任务, 2024-05--2028-12
( 3 ) 饲用活性蛋白和小分子物质创制, 负责人, 国家任务, 2022-12--2027-11
( 4 ) 猪禽动态营养需求与营养精准供给技术研究, 负责人, 国家任务, 2021-12--2026-11
( 2 ) 猪饲粮养分高效协同利用的营养代谢基础, 负责人, 国家任务, 2024-05--2028-12
( 3 ) 饲用活性蛋白和小分子物质创制, 负责人, 国家任务, 2022-12--2027-11
( 4 ) 猪禽动态营养需求与营养精准供给技术研究, 负责人, 国家任务, 2021-12--2026-11
参与会议
(1)婴幼儿营养研究模型概述与应用 第十四届亚洲营养大会 2023-09-15