基本信息
蔡祥海 男 博导 中国科学院昆明植物研究所
电子邮件: xhcai@mail.kib.ac.cn
通信地址: 云南省昆明市蓝黑路132号
邮政编码: 650201
电子邮件: xhcai@mail.kib.ac.cn
通信地址: 云南省昆明市蓝黑路132号
邮政编码: 650201
研究领域
植物化学、天然药物化学
教育背景
2001-09--2006-06 中国科学院昆明植物研究所 博士1995-09--1999-06 安徽中医学院药学系 学士
工作经历
工作简历
2014-01~现在, 中国科学院昆明植物研究所, 研究员/课题组长2008-01~2013-12,中国科学院昆明植物研究所, 职工/副研究员2006-07~2007-12,中国科学院昆明植物研究所, 职工/助理研究员1999-07~2001-08,合肥医工医药研究所, 员工
社会兼职
2021-11-01-2025-11-21,云南省抗癌协会肿瘤药物委员会, 副主任委员
教授课程
天然药化有机结构分析
专利与奖励
奖励信息
(1) Bualuang ASEAN Chair Professor Research Grant, , 专项, 2022(2) 江苏省创新创业大赛, 三等奖, 省级, 2013(3) 云南省自然科学奖, 二等奖, 省级, 2010(4) 卢家锡青年人才奖, , 院级, 2009(5) "谈家桢生命科学九源奖学金”, 二等奖, 其他, 2006
专利成果
[1] 蔡祥海, 张冰洁, 保梅芬. 白坚木碱二聚体与其药物组合物及其制备方法和应用. 中国: CN107011352A, 2017.08.04.[2] 蔡祥海, 倪玲, 钟秀虹, 保梅芬. 三尖杉降二萜类化合物及其药物组合物和其在制药中的应用. 中国: CN106674241A, 2017-05-17.[3] 蔡祥海, 罗晓东, 保梅芬. 双吲哚化合物及其药物组合物与其制备方法和用途. 中国: CN103145741A, 2013-06-12.[4] 罗晓东, 张洪彬, 李艳, 李晓宁, 蔡祥海. 吲哚生物碱类化合物及其类似物和其药物组合物与用途. 中国: CN102617609A, 2012-08-01.[5] 罗晓东, 蔡祥海, 刘亚平, 李艳, 夏成峰, 石洪凯. 水甘草碱(tabersonine)衍生物及其药物组合物和制备方法与用途. 中国: CN102558178A, 2012-07-11.[6] 蔡祥海, 张冰洁, 罗晓东, 刘亚平. 海兔烷dolabellane二萜类化合物、其药物组合物及其制备方法和用途. 中国: CN102503773A, 2012-06-20.[7] 罗晓东, 冯涛, 李艳, 王媛媛, 蔡祥海, 刘亚平. 山橙素类双吲哚化合物,其药物组合物及其制备方法和用途. 中国: CN102050832A, 2011.05.11.[8] 罗晓东, 彭涛, 朱钦昌, 刘亚平, 蔡祥海. 抗EV71的黄酮类化合物,及其在制药中的应用. 中国: CN102180853A, 2011-09-14.[9] 张仲凯, 罗晓东, 蔡祥海, 董家红, 桑鹏, 李顺林, 张廷金. 6-O-咖啡酰基飞蓬苷在制备抗烟草花叶病毒药物中的应用. 中国: CN101946770A, 2011-01-19.[10] 张仲凯, 罗晓东, 董家红, 蔡祥海, 李顺林, 桑鹏, 张廷金. 柴胡皂苷A在制备抗烟草花叶病毒药物中的应用. 中国: CN101946771A, 2011-01-19.[11] 张仲凯, 罗晓东, 董家红, 蔡祥海, 李顺林, 张廷金, 桑鹏. 磺胺在制备抗烟草花叶病毒药物中的应用. 中国: CN101946769A, 2011-01-19.[12] 张仲凯, 罗晓东, 蔡祥海, 董家红, 张廷金, 桑鹏, 李顺林. 银杏内酯B在制备抗烟草花叶病毒药物中的应用. 中国: CN101946784A, 2011-01-19.[13] 罗晓东, 蔡祥海, 李艳. 双吲哚生物碱类化合物,其药物组合物及其制备方法和用途. 中国: CN101928293A, 2010-12-29.[14] 罗晓东, 冯涛, 李艳, 蔡祥海, 王媛媛. 薄叶山橙素甲,其药物组合物及其制备方法和用途. 中国: CN101775019A, 2010-07-14.[15] 罗晓东, 冯涛, 李艳, 王媛媛, 蔡祥海, 刘亚平. 山橙素类双吲哚化合物,其药物组合物及其制备方法和用途. 中国: CN101704828, 2010-05-12.
出版信息
主要研究论文
[1] Tang, YuTing, Si, ZhuoRan, Bao, MeiFen, Cai, XiangHai. Dimeric alkaloids from the barks of Erythrina variegata as well as their occurrence. FITOTERAPIA[J]. 2023, 166: http://dx.doi.org/10.1016/j.fitote.2022.105408.[2] BaoBao Shi, Sumet Kongkiatpaiboon, Gao Chen, Johann Schinnerl, XiangHai Cai. Nematocidal alkaloids from the roots of Stemona mairei (H.Lév.)K.Krause and identification of their pharmacophoric moiety. BIOORGANIC CHEMISTRY. 2023, 130: http://dx.doi.org/10.1016/j.bioorg.2022.106239.[3] Tang, YuTing, Wu, Jing, Bao, MeiFen, Tan, QinGang, Cai, XiangHai. Dimeric Erythrina alkaloids as well as their key units from Erythrina variegata. PHYTOCHEMISTRY[J]. 2022, 198: http://dx.doi.org/10.1016/j.phytochem.2022.113160.[4] Cai, XiangHai, Shi, BaoBao, Niu, Yang, Ge, Jia, Chomicki, Guillaume, Chen, Gao. Mystery revisited: Is nocturnal colored nectar a nonadaptive floral trait?. ECOLOGY[J]. 2022, 103(5): http://dx.doi.org/10.1002/ecy.3663.[5] Yang, Jing, Niu, Yang, Sun, WeiBang, Cai, XiangHai, Chen, Gao. Intersexual mimicry and imperfect deceit of a threatened aquatic herbOttelia acuminata. JOURNAL OF SYSTEMATICS AND EVOLUTION[J]. 2022, 60(2): 377-385, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000559462000001.[6] Yu Guangxing, Wu Jing, Shi Baobao, Bao Meifen, Cai Xianghai. Enantiomeric Cephalotaxus alkaloids from seeds of Cephalotaxus oliveri. NATURAL PRODUCTS AND BIOPROSPECTING[J]. 2022, 12(4): 1-7, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=7284155&detailType=1.[7] Yu, GuangXing, Yu, Yang, JingWu, Zeng, LingHui, Schinnerl, Johann, Cai, XiangHai. Cephalotaxine homologous alkaloids from seeds of Cephalotaxus oliveri Mast. PHYTOCHEMISTRY[J]. 2022, 200: http://dx.doi.org/10.1016/j.phytochem.2022.113220.[8] XiangHai Cai. Symmetric Cytotoxicity trimeric and dimeric indole alkaloids from Bousigonia angustifolia.. Org. Chem. Front. 2021, [9] Chen, Jing, Yu, Yang, Wu, Jing, Bao, MeiFen, Kongkiatpaiboon, Sumet, Schinnerl, Johann, Cai, XiangHai. Trimeric and dimeric Aspidosperma-type alkaloids from leaves of Tabernaemontana divaricata 'Dwaft'. BIOORGANIC CHEMISTRY[J]. 2021, 116: http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000701921100004.[10] Chen, YongSheng, Zeng, ChunXia, MuellnerRiehl, Alexandra N, Wang, ZhiHeng, Sun, Lu, Schinnerl, Johann, Kongkiatpaiboon, Sumet, Kadota, Yuichi, Cai, XiangHai, Chen, Gao. Invertebrate-mediated dispersal plays an important role in shaping the current distribution of a herbaceous monocot. JOURNAL OF BIOGEOGRAPHY[J]. 2021, 48(5): 1101-1111, http://dx.doi.org/10.1111/jbi.14062.[11] Yu, Yang, Bao, MeiFen, Cai, XiangHai. Discovery of Natural Co-occurring Enantiomers of Monoterpenoid Indole Alkaloids. CHINESE JOURNAL OF CHEMISTRY[J]. 2021, 39(4): 866-872, http://dx.doi.org/10.1002/cjoc.202000574.[12] Shi, BaoBao, Wang, Fang, Chen, Gao, Schinnerl, Johann, Zeng, Ying, Cai, XiangHai. Dimeric and monomeric dihydrostilbenes from the roots of Stemona mairei together with their hypoglycemic activities. TETRAHEDRON[J]. 2021, 79: http://dx.doi.org/10.1016/j.tet.2020.131783.[13] Shi, BaoBao, Lu, JingSong, Wu, Jing, Bao, MeiFen, Cai, XiangHai. Symmetric cytotoxic trimeric and dimeric indole alkaloids isolated from Bousigonia angustifolia dagger. ORGANIC CHEMISTRY FRONTIERS[J]. 2021, 8(11): 2601-2607, http://dx.doi.org/10.1039/d0qo01565b.[14] Deng, Yan, Yu, Yang, Shi, BaoBao, Bao, MeiFen, Zhao, SiMeng, Cai, XiangHai. Monoterpenoid Indole Alkaloids with Promoting Neurite Growth from Tabernaemontana divaricata. CHINESE JOURNAL OF CHEMISTRY[J]. 2021, 39(5): 1085-1092, http://dx.doi.org/10.1002/cjoc.20220000656.[15] Yu, Yang, Bao, MeiFen, Huang, ShengZhuo, Wu, Jing, Cai, XiangHai. Vincan- and eburnan-type alkaloids from Tabernaemontana bovina and their hypoglycemic activity. PHYTOCHEMISTRY[J]. 2021, 190: http://dx.doi.org/10.1016/j.phytochem.2021.112859.[16] Tang, YuTing, Wu, Jing, Yu, Yang, Bao, MeiFen, Tan, QinGang, Schinnerl, Johann, Cai, XiangHai. Colored Dimeric Alkaloids from the Barks of Erythrina variegata and Their Neuroprotective Effects. JOURNAL OF ORGANIC CHEMISTRY[J]. 2021, 86(19): 13381-13387, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000704707200016.[17] Wu, Jing, Zhao, SiMeng, Shi, BaoBao, Bao, MeiFen, Schinnerl, Johann, Cai, XiangHai. Cage-Monoterpenoid Quinoline Alkaloids with Neurite Growth Promoting Effects from the Fruits of Melodinus yunnanensis. ORGANIC LETTERS[J]. 2020, 22(19): 7676-7680, https://www.webofscience.com/wos/woscc/full-record/WOS:000577160700053.[18] XiangHai Cai. age-monoterpenoid quinoline alkaloids with neurite growth promoting effects from the fruits of Melodinus yunnanensis. Org. Lett.. 2020, [19] Yu, Yang, Zhao, SiMeng, Bao, MeiFen, Cai, XiangHai. An Aspidosperma-type alkaloid dimer from Tabernaemontana bovina as a candidate for the inhibition of microglial activation. ORGANIC CHEMISTRY FRONTIERS[J]. 2020, 7(11): 1365-1373, http://ir.kib.ac.cn/handle/151853/72055, http://www.irgrid.ac.cn/handle/1471x/6927917, http://ir.kib.ac.cn/handle/151853/72056, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000538168500007&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=3a85505900f77cc629623c3f2907beab.[20] Yu, Yang, Bao, Fen, Wang, Yi, Zeng, Ying, Cai, XiangHai. Tacamine-type alkaloids from Tabernaemontana bovina together with their configuration determination. TETRAHEDRON[J]. 2019, 75(40): http://dx.doi.org/10.1016/j.tet.2019.130562.[21] Shi BaoBao, Chen Jing, Bao MeiFen, Zeng Ying, Cai XiangHai. Alkaloids isolated from Tabernaemontana bufalina display xanthine oxidase inhibitory activity.. PHYTOCHEMISTRY. 2019, 112060-, http://dx.doi.org/10.1016/j.phytochem.2019.112060.[22] Chen, Gao, Sun, Weibang, Wang, Xiaoxun, Kongkiatpaiboon, Sumet, Cai, Xianghai. Conserving threatened widespread species: a case study using a traditional medicinal plant in Asia. BIODIVERSITY AND CONSERVATION[J]. 2019, 28(1): 213-227, http://ir.kib.ac.cn/handle/151853/64280.[23] Shi, BaoBao, Chen, Jing, Bao, MeiFen, Zeng, Ying, Cai, XiangHai. Alkaloids isolated from Tabemaemontana bufalina display xanthine oxidase inhibitory activity. PHYTOCHEMISTRY[J]. 2019, 166: https://www.webofscience.com/wos/woscc/full-record/WOS:000484650500010.[24] Wu, Jing, Yu, Yang, Wang, Yi, Bao, MeiFen, Shi, BaoBao, Schinnerl, Johann, Cai, XiangHai. Four Yellow Monoterpenoid Quinoline Alkaloids from the Stem of Tabernaemontana bovina. ORGANIC LETTERS[J]. 2019, 21(12): 4554-4558, https://www.webofscience.com/wos/woscc/full-record/WOS:000473116000033.[25] Zhang, BingJie, Xiao, WenNa, Chen, Jing, Bao, MeiFen, Schinnerl, Johann, Wang, Qi, Cai, XiangHai. Erythrina alkaloids from leaves of Erythrina arborescens. TETRAHEDRON[J]. 2019, 75(38): http://dx.doi.org/10.1016/j.tet.2019.130515.[26] Intersexual mimicry and imperfect deceit of a threatened aquatic herb Ottelia acuminata. Journal of Systematics and Evolution[J]. 2019, [27] XiangHai Cai. Tabernabovines A–C, three monoterpenoid indole alkaloids from the leaves of Tabernaemontana bovin. Org. Lett.. 2019, [28] Yu, Yang, Bao, MeiFen, Wu, Jing, Yang, YuRong, Chen, Jing, Schinnerl, Johann, Cai, XiangHai. Tabernabovines A-C: Three Monoterpenoid Indole Alkaloids from the Leaves of Tabernaemontana bovina. ORGANIC LETTERS[J]. 2019, 21(15): 5938-5942, [29] Chen, Wei, Wang, Hui, Cheng, Mei, Ni, Ling, Zou, Li, Yang, Qin, Cai, Xianghai, Jiao, Baowei. Isoharringtonine inhibits breast cancer stem-like properties and STAT3 signaling. BIOMEDICINE & PHARMACOTHERAPY[J]. 2018, 103: 435-442, http://dx.doi.org/10.1016/j.biopha.2018.04.076.[30] Ni, Ling, Zhong, XiuHong, Chen, XiaoJiao, Zhang, BingJie, Bao, MeiFen, Cai, XiangHai. Bioactive norditerpenoids from Cephalotaxus fortunei var. alpina and C. lanceolata. PHYTOCHEMISTRY[J]. 2018, 151: 50-60, http://ir.kib.ac.cn/handle/151853/64725.[31] Zhang, BingJie, Lu, JingSong, Bao, MeiFen, Zhong, XiuHong, Ni, Ling, Wu, Jing, Cai, XiangHai. Bisindole alkaloids from Tabernaemontana corymbosa. PHYTOCHEMISTRY[J]. 2018, 152: 125-133, http://ir.kib.ac.cn/handle/151853/64705.[32] Zhang, BingJie, Liu, Cheng, Bao, MeiFen, Zhong, XiuHong, Ni, Ling, Wu, Jing, Cai, XiangHai. Novel monoterpenoid indole alkaloids from Melodinus yunnanensis. TETRAHEDRON[J]. 2017, 73(40): 5821-5826, http://dx.doi.org/10.1016/j.tet.2017.08.008.[33] Chen, XiaoJiao, Ni, Ling, Bao, MeiFen, Wang, Li, Cai, XiangHai. Abietane diterpenoids from Cephalotaxus lanceolata. NATURAL PRODUCT RESEARCH[J]. 2017, 31(21): 2473-2478, https://www.webofscience.com/wos/woscc/full-record/WOS:000412458800003.[34] Bao MeiFen, Zeng ChunXia, Liu YaPing, Zhang BingJie, Ni Ling, Luo XiaoDong, Cai XiangHai. Indole Alkaloids from Hunteria zeylanica. JOURNAL OF NATURAL PRODUCTS[J]. 2017, [35] Zhong XiuHong, Bao MeiFen, Zeng ChunXia, Zhang BingJie, Wu Jing, Zhang Yu, Cai XiangHai. Polycyclic monoterpenoid indole alkaloids from Alstonia rostrata and their reticulate derivation. PHYTOCHEMISTRY LETTERS[J]. 2017, [36] Zhang BingJie, Liu Cheng, Bao MeiFen, Zhong XiuHong, Ni Ling, Wu Jing, Cai XiangHai. Novel monoterpenoid indole alkaloids from Melodinus yunnanensis. TETRAHEDRON[J]. 2017, [37] Wu, Jing, Zhang, BingJie, Xiao, WenNa, Bao, MeiFen, Cai, XiangHai. Alkaloids from the flower of Erythrina arborescens. RSC ADVANCES[J]. 2017, 7(81): 51245-51251, https://www.webofscience.com/wos/woscc/full-record/WOS:000414780700019.[38] Ni, Ling, Schinnerl, Johann, Bao, Meifen, Zhang, Bingjie, Wu, Jing, Cai, Xianghai. Two key biogenetic intermediates of Cephalotaxus alkaloids from Cephalotaxus oliveri and C. lanceolata. TETRAHEDRON LETTERS[J]. 2016, 57(47): 5201-5204, http://dx.doi.org/10.1016/j.tetlet.2016.10.026.[39] XiangHai Cai. wo New Lignans from Twigs of Aglaia Odorata. J.Asian Nat. Prod. Res.. 2016, [40] Zhang, BingJie, Wu, Bin, Bao, MeiFen, Nia, Ling, Cai, XiangHai. New dimeric and trimeric Erythrina alkaloids from Erythrina variegata. RSC ADVANCES[J]. 2016, 6(91): 87863-87868, http://www.irgrid.ac.cn/handle/1471x/1175700.[41] Zhang, BingJie, Teng, XiFeng, Bao, MeiFen, Zhong, XiuHong, Ni, Ling, Cai, XiangHai. Cytotoxic indole alkaloids from Tabemaemontana officinalis. PHYTOCHEMISTRY[J]. 2015, 120: 46-52, http://www.irgrid.ac.cn/handle/1471x/1029020.[42] BingJie Zhang, XiFeng Teng, MeiFen Bao, XiuHong Zhong, Ling Ni, XiangHai Cai. Cytotoxic indole alkaloids from Tabernaemontana officinalis. PHYTOCHEMISTRY. 2015, 46-52, http://dx.doi.org/10.1016/j.phytochem.2014.12.025.[43] Chen, Gao, Ma, XiaoKai, Juergens, Andreas, Lu, Jun, Liu, ErXi, Sun, WeiBang, Cai, XiangHai. Mimicking Livor Mortis: a Well-Known but Unsubstantiated Color Profile in Sapromyiophily. JOURNAL OF CHEMICAL ECOLOGY[J]. 2015, 41(9): 808-815, http://www.irgrid.ac.cn/handle/1471x/1029126.[44] Zhang, BingJie, Bao, MeiFen, Zeng, ChunXia, Zhong, XiuHong, Ni, Ling, Zeng, Ying, Cai, XiangHai. Dimeric Erythrina Alkaloids from the Flower of Erythrina variegata. ORGANIC LETTERS[J]. 2014, 16(24): 6400-6403, http://www.irgrid.ac.cn/handle/1471x/959014.[45] Bao, MeiFen, Yan, JuMing, Cheng, GuiGuang, Li, XingYao, Liu, YaPing, Li, Yan, Cai, XiangHai, Luo, XiaoDong. Cytotoxic Indole Alkaloids from Tabernaemontana divaricata. JOURNAL OF NATURAL PRODUCTS[J]. 2013, 76(8): 1406-1412, https://www.webofscience.com/wos/woscc/full-record/WOS:000323630500003.[46] XiangHai Cai. Cytotoxic Indole Alkaloids from Tabernaemontana divaricate. J. Nat. Prod.. 2013, [47] XiangHai Cai. Melosuavines A-H, Cytotoxic bisindole alkaloids from Melodinus suaceolens. 2013, [48] Liu, YaPing, Zhao, YunLi, Feng, Tao, Cheng, GuiGuang, Zhang, BaoHong, Li, Yan, Cai, XiangHai, Luo, XiaoDong. Melosuavines A-H, Cytotoxic Bisindole Alkaloid Derivatives from Melodinus suaveolens. JOURNAL OF NATURAL PRODUCTS[J]. 2013, 76(12): 2322-2329, http://www.irgrid.ac.cn/handle/1471x/947793.[49] Cai, XiangHai, Li, Yan, Liu, YaPing, Li, XiaoNing, Bao, MeiFen, Luo, XiaoDong. Alkaloids from Melodinus yunnanensis. PHYTOCHEMISTRY[J]. 2012, 83: 116-124, http://dx.doi.org/10.1016/j.phytochem.2012.06.013.[50] Cai, XiangHai, Bao, MeiFen, Zhang, Yu, Zeng, ChunXia, Liu, YaPing, Luo, XiaoDong. A New Type of Monoterpenoid Indole Alkaloid Precursor from Alstonia rostrata. ORGANIC LETTERS[J]. 2011, 13(14): 3568-3571, http://www.irgrid.ac.cn/handle/1471x/392982.[51] Cai, XiangHai, Wang, YuanYuan, Zhao, PeiJi, Li, Yan, Luo, XiaoDong. Dolabellane diterpenoids from Aglaia odorata. PHYTOCHEMISTRY[J]. 2010, 71(8-9): 1020-1024, http://dx.doi.org/10.1016/j.phytochem.2010.03.005.[52] Cai, XiangHai, Tan, QinGang, Liu, YaPing, Feng, Tao, Du, ZhiZhi, Li, WeQi, Luo, XiaoDong. A cage-monoterpene indole alkaloid from Alstonia scholaris. ORGANIC LETTERS[J]. 2008, 10(4): 577-580, http://www.irgrid.ac.cn/handle/1471x/501456.[53] Cai, XiangHai, Luo, XiaoDong. A new tetranortriterpenoid from Munronia delavayi. CHINESE JOURNAL OF CHEMISTRY[J]. 2007, 25(7): 986-988, http://lib.cqvip.com/Qikan/Article/Detail?id=24859975.[54] Cai, XiangHai, Du, ZhiZhi, Luo, XiaoDong. Unique monoterpenoid indole alkaloids from Alstonia scholaris. ORGANIC LETTERS[J]. 2007, 9(9): 1817-1820, https://www.webofscience.com/wos/woscc/full-record/WOS:000245799200051.[55] Cai, XiangHai, Luo, XiaoDong. Alkaloids from Stemona mairei. PLANTA MEDICA[J]. 2007, 73(2): 170-173, https://www.webofscience.com/wos/woscc/full-record/WOS:000244859600011.[56] Cai, XiangHai, Luo, XiaoDong, Zhou, Jun, Hao, XiaoJiang. A new pregnane from Munronia delavayi Franch (Meliaceae). JOURNAL OF INTEGRATIVE PLANT BIOLOGY[J]. 2006, 48(9): 1126-1128, https://www.webofscience.com/wos/woscc/full-record/WOS:000240201900016.[57] Xiang-Hai Cai, Xiao-Dong Luo, Jun Zhou, Xiao-Jiang Hao. A New Pregnane from Munronia delavayi Franc (Meliaceae). 植物学报:英文版[J]. 2006, 48(9): 1126-1128, http://lib.cqvip.com/Qikan/Article/Detail?id=22989139.[58] Cai, XH, Luo, XD, Zhou, J, Hao, XJ. Compound representatives of a new type of triterpenoid from Aglaia odorata. ORGANICLETTERS[J]. 2005, 7(14): 2877-2879, https://www.webofscience.com/wos/woscc/full-record/WOS:000230213100019.[59] Cai, XH, Luo, XD, Zhou, J, Hao, XJ. Quinones from Chirita eburnea. JOURNAL OF NATURAL PRODUCTS[J]. 2005, 68(5): 797-799,
科研活动
主要科研项目
( 1 ) 国产萝芙木亚科植物中新生物碱发现及其抗肿瘤活性研究, 主持, 国家级, 2012-01--2015-12( 2 ) 水甘草碱及柯南因-依波加聚合体生物碱结构优化与抗肿瘤作用机制研究, 主持, 国家级, 2014-06--2017-12( 3 ) 生物碱/色素成分应用研究, 主持, 院级, 2013-01--2017-12( 4 ) 抗肿瘤生物碱作用机制与代谢动力学研究, 主持, 省级, 2016-01--2019-08( 5 ) 基于三尖杉生物碱构效规律的新颖抗肿瘤酯碱的挖掘与构建, 主持, 国家级, 2019-01--2022-12( 6 ) 植物活性成分的提取与纯化研究, 主持, 院级, 2019-07--2021-06( 7 ) 灯台叶天然药物5类新药临床前研究, 主持, 国家级, 2013-01--2015-12( 8 ) 植物甙(黄芩金银花活性成分)抑菌抗炎机制研究, 主持, 院级, 2020-09--2021-10( 9 ) 双吲哚长春碱类抗肿瘤药物结构简化的研究及其天然类似物挖掘, 主持, 省级, 2022-01--2024-12
参与会议
(1)抗肿瘤生物碱成分再研究 中国化学会第十二届全国天然有机化学学术会议 2018-07-28
指导学生
已指导学生
钟秀虹 硕士研究生 105500-药学
倪玲 硕士研究生 105500-药学
吴静 硕士研究生 105500-药学
邓妍 硕士研究生 078001-药物化学
张冰洁 博士研究生 100701-药物化学
黄煊益 硕士研究生 105500-药学
杨梦悦 硕士研究生 105500-药学
吴慰 硕士研究生 105500-药学
石宝宝 硕士研究生 105500-药学
吴静 博士研究生 100701-药物化学
郁阳 博士研究生 100701-药物化学
石宝宝 博士研究生 100701-药物化学
现指导学生
陈静 博士研究生 100701-药物化学
保梅芬 博士研究生 100701-药物化学
余光兴 硕士研究生 078001-药物化学
谭成勇 硕士研究生 078001-药物化学
林婧 博士研究生 100701-药物化学
何智承 博士研究生 100706-药理学
叶丽丽 硕士研究生 105500-药学
汪永悦 博士研究生 100701-药物化学