基本信息
吴逵  男  硕导  其他
电子邮件: wukui@genomics.cn
通信地址: 广东省深圳市盐田区华大时空大楼8楼
邮政编码:

招生信息

   
招生专业
0710Z1-基因组学
0710J3-生物信息学
招生方向
癌症基因组学,癌症系统生物学
肿瘤免疫,单细胞组学,癌症演化
大数据技术与应用,人工智能分析算法开发

教育背景

2015-03--2019-03   丹麦哥本哈根大学   博士
2007-07--2009-06   中山大学   硕士
2003-09--2007-06   中山大学   学士

工作经历

   
工作简历
2016-08~现在, 深圳华大生命科学研究院, 癌症研究主任科学家
2013-01~2016-08,深圳华大生命科学研究院, 肿瘤研究中心科研主管
2009-07~2013-01,深圳华大生命科学研究院, 科技体系研发项目组长
社会兼职
2023-01-14-今,广东省临床医学学会精准医疗专业委员会常务委员,
2021-11-12-今,中国医药生物技术协会精准医疗分会委员,
2017-10-26-今,广东省精准医学应用学会结直肠癌分会副主任委员,

教授课程

癌症多组学研究与精准医学探索
肿瘤基因检测和指导用药
基因组学研究进展与大科学设计

专利与奖励

   
奖励信息
(1) 脊椎动物天然免疫多样性的起源, 一等奖, 省级, 2019
专利成果
( 1 ) 一种共提取total DNA、total RNA和总蛋白的方法, 发明专利, 2023, 第 3 作者, 专利号: CN116949035A

( 2 ) 膀胱癌尿液微生物标志物及其应用, 发明专利, 2024, 第 3 作者, 专利号: CN117402962A

( 3 ) 固定平衡文库、其制备方法及提高基于亚硫酸盐处理文库测序质量的方法, 发明专利, 2023, 第 4 作者, 专利号: CN117230535A

( 4 ) 空间组学数据的处理方法、电子设备及介质, 发明专利, 2023, 第 4 作者, 专利号: CN116959586A

( 5 ) 测序文库的构建方法及试剂盒, 发明专利, 2023, 第 7 作者, 专利号: CN116042767A

( 6 ) 棒状杆菌作为尿液微生物标志物在制备用于检测膀胱癌的相关检测产品中的应用, 发明专利, 2022, 第 3 作者, 专利号: CN114686607A

( 7 ) 棒状杆菌作为尿液微生物标志物在制备用于检测膀胱癌的相关检测产品中的应用, 发明授权, 2023, 第 3 作者, 专利号: CN114686607B

( 8 ) 基于DNA甲基化水平确定样本类型的系统、可读介质及其应用, 发明专利, 2022, 第 3 作者, 专利号: CN114566220A

( 9 ) 检测膀胱癌的标志物及检测该标志物的引物对及其应用, 发明专利, 2022, 第 3 作者, 专利号: CN113957160A

( 10 ) 一种可以改善全基因组甲基化测序偏向性的建库方法, 发明专利, 2021, 第 5 作者, 专利号: CN112553298A

( 11 ) 结直肠癌标志物及其应用, 发明专利, 2019, 第 3 作者, 专利号: CN109762900A

( 12 ) 咽颊炎链球菌的特异基因序列、其检测引物及其应用, 发明专利, 2020, 第 4 作者, 专利号: CN110872632A

( 13 ) 结直肠癌标志物及其应用, 发明专利, 2020, 第 4 作者, 专利号: CN110857450A

( 14 ) 构建DNA甲基化文库的方法及其应用, 发明专利, 2020, 第 6 作者, 专利号: CN110760936A

( 15 ) 一种结直肠癌肿瘤标志物及其检测方法与装置, 发明专利, 2018, 第 4 作者, 专利号: CN108753974A

( 16 ) 结直肠癌肿瘤标志物及其检测方法与装置, 发明专利, 2022, 第 4 作者, 专利号: CN114438214A

( 17 ) 结直肠癌肿瘤标志物及其检测方法与装置, 发明专利, 2022, 第 4 作者, 专利号: CN114438214A

( 18 ) 确定待测样本类型的方法及系统, 发明专利, 2021, 第 3 作者, 专利号: CN112739828A

( 19 ) 一种用于肝癌检测的基因集及其panel检测设计方法, 发明专利, 2018, 第 12 作者, 专利号: CN108753967A

( 20 ) 恶性淋巴瘤标志物及其应用, 发明专利, 2020, 第 6 作者, 专利号: CN111655868A

( 21 ) 一种small RNA的文库构建及测序方法, 发明专利, 2018, 第 3 作者, 专利号: CN108060460A

( 22 ) 基于DNA测序数据的样本来源检测方法、装置和存储介质, 发明授权, 2023, 第 3 作者, 专利号: CN110462056B

( 23 ) 基于DNA测序数据的样本来源检测方法、装置和存储介质, 发明专利, 2019, 第 3 作者, 专利号: CN110462056A

( 24 ) 肺腺癌生物标记物及其应用, 专利授权, 2018, 第 1 作者, 专利号: CN107849569A

( 25 ) 测序数据处理装置和方法, 专利授权, 2017, 第 7 作者, 专利号: CN107077533A

( 26 ) 测序数据处理装置和方法, 专利授权, 2017, 第 7 作者, 专利号: CN107077538A

出版信息

   
发表论文
[1] Yunfan Sun, Pin Wu, Zefan Zhang, Zejian Wang, Kaiqian Zhou, Minfang Song, Yuan Ji, Fenglin Zang, Limu Lou, Keqiang Rao, Pengxiang Wang, Yutong Gu, Jie Gu, Binbin Lu, Limeng Chen, Xiuqi Pan, Xiaojing Zhao, Lihua Peng, Dongbing Liu, Xiaofang Chen, Kui Wu, Penghui Lin, Liang Wu, Yulin Su, Min Du, Yingyong Hou, Xinrong Yang, Shuangjian Qiu, Yinghong Shi, Huichuan Sun, Jian Zhou, Xingxu Huang, David H Peng, Liye Zhang, Jia Fan. Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma. CANCER CELL. 2024, 第 21 作者42(1): 135-156.e17, http://dx.doi.org/10.1016/j.ccell.2023.11.010.
[2] Pecori, Riccardo, Ren, Weicheng, Pirmoradian, Mohammad, Binder, Marco, Papavasiliou, Nina, Wang, Xianhuo, Liu, Dongbing, Berglund, Mattias, Li, Wei, Tasakis, Rafail Nikolaos, Di Giorgio, Salvatore, Ye, Xiaofei, Li, Xiaobo, Wu, Kui, Helm, Dominic, Arnold, Annette, Wust, Sandra, Schneider, Martin, Selvasaravanan, KarthikDevi, Fuell, Yvonne, Stafforst, Thorsten, Amini, RoseMarie, Sonnevi, Kristina, Enblad, Gunilla, Sander, Birgitta, Wahlin, Bjorn Engelbrekt, Zhang, Huilai, Papavasiliou, F Nina, PanHammarstrom, Qiang. ADAR1-mediated RNA editing promotes B cell lymphomagenesis. ISCIENCE[J]. 2023, 第 14 作者26(6): http://dx.doi.org/10.1016/j.isci.2023.106864.
[3] Tao Tan, Dmitri Mouradov, Margaret Lee, Grace Gard, Yumiko Hirokawa, Shan Li, Cong Lin, Fuqiang Li, Huijuan Luo, Kui Wu, Michelle Palmieri, Evelyn Leong, Jordan Clarke, Anuratha Sakthianandeswaren, Helen Brasier, Jeanne Tie, Niall C Tebbutt, Azim Jalali, Rachel Wong, Antony W Burgess, Peter Gibbs, Oliver M Sieber. Unified framework for patient-derived, tumor-organoid-based predictive testing of standard-of-care therapies in metastatic colorectal cancer. CELL REPORTS MEDICINE. 2023, 第 10 作者4(12): http://dx.doi.org/10.1016/j.xcrm.2023.101335.
[4] Qing Zhou, Jingnan Yuan, Kui Wu, Jun Yin, Lijie Tan. Neoadjuvant immunotherapy for resectable esophagal squamous cell carcinoma: An ace up the sleeve. CLINICAL AND TRANSLATIONAL MEDICINE[J]. 2023, 第 3 作者13(9): n/a-n/a, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514370/.
[5] Yin, Jun, Yuan, Jingnan, Li, Yunjin, Fang, Yong, Wang, Ruoxi, Jiao, Heng, Tang, Han, Zhang, Shaoyuan, Lin, Siyun, Su, Feng, Gu, Jianmin, Jiang, Tian, Lin, Dong, Huang, Zhiliang, Du, Chaoxiang, Wu, Kui, Tan, Lijie, Zhou, Qing. Neoadjuvant adebrelimab in locally advanced resectable esophageal squamous cell carcinoma: a phase 1b trial. NATURE MEDICINE. 2023, 第 16 作者  通讯作者  29(8): 2068-2078, http://dx.doi.org/10.1038/s41591-023-02469-3.
[6] Fanfan Xie, Ding Ding, Cong Lin, Dea Cunningham, Michael Wright, Ammar A Javed, Nilo Azad, Valerie Lee, Ross Donehower, Ana De JesusAcosta, Dung T Le, Michael Pishvaian, Eun Ji Shin, Anne Marie Lennon, Mouen Khashab, Vikesh Singh, Alison P Klein, Nicholas J Roberts, Amy HackerPrietz, Thomas McPhaul, Richard A Burkhart, William R Burns, Amol Narang, Atif Zaheer, Elliot K Fishman, Elizabeth D Thompson, Robert Anders, Jun Yu, Jin He, Christopher L Wolfgang, Lei Zheng, Dongbing Liu, Kui Wu, Daniel A Laheru. RAD51B Harbors Germline Mutations Associated With Pancreatic Ductal Adenocarcinoma. JCO PRECISION ONCOLOGY. 2022, 第 33 作者6: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848593/.
[7] Ye, Xiaofei, Maglione, Paul J, Wehr, Claudia, Li, Xiaobo, Wang, Yating, Abolhassani, Hassan, Deripapa, Elena, Liu, Dongbing, Borte, Stephan, Du, Likun, Wan, Hui, Ploetner, Andreas, Giannoula, Yvonne, Ko, HuaiBin, Hou, Yong, Zhu, Shida, Grossman, Jennifer K, Sander, Birgitta, Grimbacher, Bodo, Hammarstrom, Lennart, Fedorova, Alina, Rosenzweig, Sergio D, Shcherbina, Anna, Wu, Kui, Warnatz, Klaus, CunninghamRundles, Charlotte, PanHammarstrom, Qiang. Genomic characterization of lymphomas in patients with inborn errors of immunity. BLOOD ADVANCES[J]. 2022, 第 24 作者6(18): 5403-5414, http://dx.doi.org/10.1182/bloodadvances.2021006654.
[8] Zhang, Xiuying, Ren, Huahui, Zhao, Cuiling, Shi, Zhun, Qiu, Li, Yang, Fangming, Zhou, Xianghai, Han, Xueyao, Wu, Kui, Zhong, Huanzi, Li, Yufeng, Li, Junhua, Ji, Linong. Metagenomic analysis reveals crosstalk between gut microbiota and glucose-lowering drugs targeting the gastrointestinal tract in Chinese patients with type 2 diabetes: a 6 month, two-arm randomised trial. DIABETOLOGIA[J]. 2022, 第 9 作者65(10): 1613-1626, http://dx.doi.org/10.1007/s00125-022-05768-5.
[9] Li, Nannan, Wang, Lei, Liang, Han, Lin, Cong, Yi, Ji, Yang, Qin, Luo, Huijuan, Luo, Tian, Zhang, Liwei, Li, Xiaojian, Wu, Kui, Li, Fuqiang, Li, Ningchen. Detecting and monitoring bladder cancer with exfoliated cells in urine. FRONTIERS IN ONCOLOGY[J]. 2022, 第 11 作者  通讯作者  12: http://dx.doi.org/10.3389/fonc.2022.986692.
[10] Liu, Jun, Li, Jingpei, Lin, Wanli, Shao, Di, Depypere, Lieven, Zhang, Zhifeng, Li, Zhuoyi, Cui, Fei, Du, Zesen, Zeng, Yuan, Jiang, Shunjun, He, Ping, Gu, Xia, Chen, Huai, Zhang, Hai, Lin, Xiaowei, Huang, Haoda, Lv, Wenqiang, Cai, Weiming, Liang, Wenhua, Liang, Hengrui, Jiang, Wenxi, Wang, Wei, Xu, Ke, Cai, Weipeng, Wu, Kui, Lerut, Toni, Fu, Junhui, He, Jianxing. Neoadjuvant camrelizumab plus chemotherapy for resectable, locally advanced esophageal squamous cell carcinoma (NIC-ESCC2019): A multicenter, phase 2 study. INTERNATIONAL JOURNAL OF CANCER[J]. 2022, 第 26 作者151(1): 128-137, https://www.doi.org/10.1002/ijc.33976.
[11] Nie, Man, Ren, Weicheng, Ye, Xiaofei, Berglund, Mattias, Wang, Xianhuo, Fjorden, Karin, Du, Likun, Giannoula, Yvonne, Lei, Dexin, Su, Wenjia, Li, Wei, Liu, Dongbing, Linderoth, Johan, Jiang, Chengyi, Bao, Huijing, Jiang, Wenqi, Huang, Huiqiang, Hou, Yong, Zhu, Shida, Enblad, Gunilla, Jerkeman, Mats, Wu, Kui, Zhang, Huilai, Amini, RoseMarie, Li, ZhiMing, PanHammarstrom, Qiang. The dual role of CD70 in B-cell lymphomagenesis. CLINICAL AND TRANSLATIONAL MEDICINE[J]. 2022, 第 22 作者12(12): https://www.doi.org/10.1002/ctm2.1118.
[12] Zhang, Bin, Liang, Han, Liu, Weiran, Zhou, Xinlan, Qiao, Sitan, Li, Fuqiang, Tian, Pengfei, Li, Chenguang, Ma, Yuchen, Zhang, Hua, Zhang, Zhenfa, Nanjo, Shigeki, Russo, Alessandro, PuigButille, Joan Anton, Wu, Kui, Wang, Changli, Zhao, Xin, Yue, Dongsheng. A novel approach for the non-invasive diagnosis of pulmonary nodules using low-depth whole-genome sequencing of cell-free DNA. TRANSLATIONAL LUNG CANCER RESEARCH[J]. 2022, 第 15 作者  通讯作者  11(10): 2094-+, http://dx.doi.org/10.21037/tlcr-22-647.
[13] Ren, Weicheng, Wang, Xianhuo, Yang, Mingyu, Wan, Hui, Li, Xiaobo, Ye, Xiaofei, Meng, Bing, Li, Wei, Yu, Jingwei, Lei, Mengyue, Xie, Fanfan, Jiang, Wenqi, Kimby, Eva, Huang, Huiqiang, Liu, Dongbing, Li, ZhiMing, Wu, Kui, Zhang, Huilai, PanHammarstrom, Qiang. Distinct clinical and genetic features of hepatitis B virus-associated follicular lymphoma in Chinese patients. BLOOD ADVANCES[J]. 2022, 第 17 作者  通讯作者  6(9): 2731-2744, http://dx.doi.org/10.1182/bloodadvances.2021006410.
[14] Lin, Youpei, Peng, Lihua, Dong, Liangqing, Liu, Dongbing, Ma, Jiaqiang, Lin, Jian, Chen, Xiaofang, Lin, Penghui, Song, Guohe, Zhang, Mao, Liu, Yuming, Rao, Junhua, Wei, Chen, Lu, Ye, Zhang, Shu, Ding, Guangyu, Peng, Zhenyu, Lu, Haorong, Wang, Xiaoying, Zhou, Jian, Fan, Jia, Wu, Kui, Gao, Qiang. Geospatial Immune Heterogeneity Reflects the Diverse Tumor-Immune Interactions in Intrahepatic Cholangiocarcinoma. CANCER DISCOVERY[J]. 2022, 第 22 作者  通讯作者  12(10): 2350-2371, 
[15] Ye, Xiaofei, Wang, Lei, Nie, Man, Wang, Yuyao, Dong, Shichen, Ren, Weicheng, Li, Guibo, Li, ZhiMing, Wu, Kui, PanHammarstrom, Qiang. A single-cell atlas of diffuse large B cell lymphoma. CELL REPORTS[J]. 2022, 第 9 作者  通讯作者  39(3): http://dx.doi.org/10.1016/j.celrep.2022.110713.
[16] Zhao, Shen, Zhang, Zhonghan, Zhan, Jianhua, Zhao, Xin, Chen, Xinru, Xiao, Liyun, Wu, Kui, Ma, Yuxiang, Li, Mengzhen, Yang, Yunpeng, Fang, Wenfeng, Zhao, Hongyun, Zhang, Li. Utility of comprehensive genomic profiling in directing treatment and improving patient outcomes in advanced non-small cell lung cancer. BMC MEDICINE[J]. 2021, 第 7 作者19(1): http://dx.doi.org/10.1186/s12916-021-02089-z.
[17] Man Nie, Likun Du, Weicheng Ren, Julia Joung, Xiaofei Ye, Xi Shi, Sibel Ciftci, Dongbing Liu, Kui Wu, Feng Zhang, Qiang PanHammarstrm. Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma. CELL DEATH AND DISEASE[J]. 2021, 第 9 作者12(5): 1-11, https://doaj.org/article/b9069402ae794d37b6e1f0f69aa5692f.
[18] Ye, Xiaofei, Ren, Weicheng, Liu, Dongbing, Li, Xiaobo, Li, Wei, Wang, Xianhuo, Meng, FeiLong, Yeap, LengSiew, Hou, Yong, Zhu, Shida, Casehs, Rafael, Zhang, Huilai, Wu, Kui, PanHammarstrom, Qiang. Genome-wide mutational signatures revealed distinct developmental paths for human B cell lymphomas. JOURNAL OF EXPERIMENTAL MEDICINE[J]. 2021, 第 13 作者  通讯作者  218(2): http://dx.doi.org/10.1084/jem.20200573.
[19] Zhou, Hanlin, Li, Guibo, Yin, Jianhua, Wang, Ting, Hu, Hong, Li, Tong, Zhou, Qing, Hu, Jintao, Wang, Lei, Dong, Shichen, Wei, Chen, Zhang, Cuijuan, Lu, Ye, Zhou, Wenbin, Huang, Chen, Yang, Huanming, Zhou, Dongxian, Wang, Ling, Wu, Kui. Neoadjuvant chemotherapy alters peripheral and tumour-infiltrating immune cells in breast cancer revealed by single-cell RNA sequencing. CLINICAL AND TRANSLATIONAL MEDICINE. 2021, 第 19 作者  通讯作者  11(12): http://dx.doi.org/10.1002/ctm2.621.
[20] Liang, Han, Li, Fuqiang, Qiao, Sitan, Zhou, Xinlan, Xie, Guoyun, Zhao, Xin, Zhang, Yongwei, Wu, Kui. Whole-genome sequencing of cell-free DNA yields genome-wide read distribution patterns to track tissue of origin in cancer patients. CLINICAL AND TRANSLATIONAL MEDICINE[J]. 2020, 第 8 作者  通讯作者  10(6): https://doaj.org/article/7eafbea7f7da410785fd94ddfe1aa042.
[21] Hong, Xiafei, Qiao, Sitan, Li, Fuqiang, Wang, Wenze, Jiang, Rui, Wu, Huanwen, Chen, Hao, Liu, Lulu, Peng, Junya, Wang, Jing, Jia, Congwei, Liang, Xiaolong, Dai, Hongmei, Jiang, Jialin, Zhang, Taiping, Liao, Quan, Dai, Menghua, Cong, Lin, Han, Xianlin, Guo, Dan, Liang, Zhiyong, Li, Dongjing, Zheng, Zetian, Ye, Chen, Li, Siliang, Zhao, Yupei, Wu, Kui, Wu, Wenming. Whole-genome sequencing reveals distinct genetic bases for insulinomas and non-functional pancreatic neuroendocrine tumours: leading to a new classification system. GUT[J]. 2020, 第 27 作者  通讯作者  69(5): 877-887, http://dx.doi.org/10.1136/gutjnl-2018-317233.
[22] Calabrese, Claudia, Davidson, Natalie R, Demircioglu, Deniz, Fonseca, Nuno A, He, Yao, Kahles, Andre, KjongVan Lehmann, Liu, Fenglin, Shiraishi, Yuichi, Soulette, Cameron M, Urban, Lara, Greger, Liliana, Li, Siliang, Liu, Dongbing, Perry, Marc D, Xiang, Qian, Zhang, Fan, Zhang, Junjun, Bailey, Peter, Erkek, Serap, Hoadley, Katherine A, Hou, Yong, Huska, Matthew R, Kilpinen, Helena, Korbel, Jan O, Marin, Maximillian G, Markowski, Julia, Nandi, Tannistha, PanHammarstrom, Qiang, Pedamallu, Chandra Sekhar, Siebert, Reiner, Stark, Stefan G, Su, Hong, Tan, Patrick, Waszak, Sebastian M, Yung, Christina, Zhu, Shida, Awadalla, Philip, Creighton, Chad J, Meyerson, Matthew, Ouellette, B F Francis, Wu, Kui, Yang, Huanming, Brazma, Alvis, Brooks, Angela N, Goke, Jonathan, Raetsch, Gunnar, Schwarz, Roland F, Stegle, Oliver, Zhang, Zemin, PCAWG Transcriptome Core Grp, PCAWG Transcriptome Working Grp, PCAWG Consortium. Genomic basis for RNA alterations in cancer. NATURE[J]. 2020, 第 42 作者578(7793): 129-+, http://dx.doi.org/10.1038/s41586-020-1970-0.
[23] Campbell, Peter J, Getz, Gad, Korbel, Jan O, Stuart, Joshua M, Jennings, Jennifer L, Stein, Lincoln D, Perry, Marc D, NahalBose, Hardeep K, Ouellette, B F Francis, Li, Constance H, Rheinbay, Esther, Nielsen, G Petur, Sgroi, Dennis C, Wu, ChinLee, Faquin, William C, Deshpande, Vikram, Boutros, Paul C, Lazar, Alexander J, Hoadley, Katherine A, Louis, David N, Dursi, L Jonathan, Yung, Christina K, Bailey, Matthew H, Saksena, Gordon, Raine, Keiran M, Buchhalter, Ivo, Kleinheinz, Kortine, Schlesner, Matthias, Zhang, Junjun, Wang, Wenyi, Wheeler, David A, Ding, Li, Simpson, Jared T, OConnor, Brian D, Yakneen, Sergei, Ellrott, Kyle, Miyoshi, Naoki, Butler, Adam P, Royo, Romina, Shorser, Solomon, I, Vazquez, Miguel, Rausch, Tobias, Tiao, Grace, Waszak, Sebastian M, RodriguezMartin, Bernardo, Shringarpure, Suyash, Wu, DaiYing, Demidov, German M, Delaneau, Olivier, Hayashi, Shuto, Imoto, Seiya, Habermann, Nina, Segre, Ayellet, V, Garrison, Erik, Cafferkey, Andy, Alvarez, Eva G, Maria 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科研活动

   
科研项目
( 1 ) 肝癌免疫异质性与免疫逃逸形成的空间转录组研究, 负责人, 国家任务, 2024-01--2027-12
( 2 ) 胶质瘤演进过程中异质性和免疫微环境可视化智慧诊断, 参与, 国家任务, 2023-01--2026-12
( 3 ) 单细胞代谢标志物分析仪与试剂研发, 负责人, 地方任务, 2023-01--2025-12
( 4 ) 癌症早期预测技术研发, 负责人, 研究所自主部署, 2022-01--2026-12
( 5 ) 广东省人类疾病基因组重点实验室, 负责人, 地方任务, 2020-06--2023-05
( 6 ) 基于多组学分析综合研究非小细胞肺癌免疫组学特征及其免疫逃逸机制, 负责人, 研究所自主部署, 2020-03--2022-03
( 7 ) 深圳市单细胞组学重点实验室, 负责人, 地方任务, 2020-01--2022-03
( 8 ) 结直肠癌个体化治疗靶标发现和精准用药临床研究, 参与, 地方任务, 2019-03--2022-03
( 9 ) 癌症多组学大数据, 负责人, 研究所自主部署, 2018-11--2021-12
( 10 ) 肿瘤高通量测序基因检测诊疗的应用示范, 负责人, 地方任务, 2017-07--2019-06
( 11 ) 肺癌的诊疗规范及应用方案的精准化研究, 参与, 国家任务, 2016-01--2019-12
( 12 ) 以生物组学特征与多模态功能影像为基础的多线束精准放疗方案研究, 参与, 国家任务, 2016-01--2018-12
( 13 ) 基于高通量测序的单细胞分析技术的研发及应用, 负责人, 地方任务, 2015-08--2017-08
( 14 ) 深圳市乳腺癌高发人群基因筛查技术应用示范, 参与, 地方任务, 2014-12--2016-12
( 15 ) 与重要疾病相关的基因组学和生物信息学技术, 参与, 国家任务, 2012-01--2015-12
( 16 ) 肺癌和糖尿病全基因遗传变异分析和新遗传标志物的筛选, 参与, 国家任务, 2009-12--2011-12
参与会议
(1)基于单细胞组学的癌症生物学研究    第二届中国肿瘤胃肠病学年会   2022-07-02
(2)基于时空组学的癌症创新研究与精准医学探索   第七届细胞与肿瘤精准医疗高峰论坛   2021-10-27
(3)基于时空组学的癌症创新研究   国际检验医学精准诊疗大会   2021-07-01
(4)Comprehensive Omics Analysis to Explore Applications in Clinical Oncology   2021-04-28
(5)基于组学技术的消化道肿瘤诊疗精准化探索   第三届粤港澳消化系统疾病精准医学及大数据研讨会   2020-11-22
(6)肿瘤多组学研究思路浅析   中国抗癌协会青委会深圳高峰论坛   2020-11-21
(7)妇科肿瘤遗传学基础   2020年中南妇科肿瘤论坛   2020-10-24
(8)Discovery of RNA alterations in Cancer   第二届粤港澳消化系统疾病精准医学及大数据研讨会   2020-05-27
(9)癌症免疫组学进展   第一届粤港澳消化系统疾病精准医学及大数据研讨会   2019-12-07
(10)大数据分析—癌症精准医学新视角   广东省临床医学学会精准医疗专业委员会年会   2019-04-20
(11)Cancer Genomic Study towards Precision Medicine_AUS   2019-02-24
(12)Liquid Biopsy in Precision Oncology   2018-11-18
(13)高通量测序与大数据分析在肿瘤诊断与治疗方面的应用   中华医学会中青年肿瘤学会会议   2018-06-09
(14)肺癌基因多组学研究进展及临床应用探索   广东省医学会第三次胸外科学学术会议   2017-12-09
(15)Decipher inter- and intratumoral heterogeneity to facilitate cancer precision medicine   2017-11-19

指导学生

已指导学生

陆叶  硕士研究生  086000-生物与医药  

李梦婷  硕士研究生  086000-生物与医药  

杨拯滔  硕士研究生  0710J3-生物信息学  

潘智康  硕士研究生  086000-生物与医药  

现指导学生

李雅蕊  硕士研究生  086000-生物与医药  

巩尊运  硕士研究生  0710J3-生物信息学  

徐高洋  硕士研究生  0710J3-生物信息学  

胡智豪  硕士研究生  0710J3-生物信息学  

冯秀杰  硕士研究生  086000-生物与医药